Alicia Wytlie, Jamie Shea, Jonathan Northcroft, P B, Waldemar Januszczak, John Dugdale, Michael Prescott, Robin Cook, Philip Marsden, T G, Matthew Wall, Barbara Hall, Norman Waterson, Christopher Morgan Religious Affairs Correspondent, W Anthony Pike, Simon Tranter, Philip Norman, Thomas Jones, Dan Pearson, John Peter, J K, Emma Moore, Amanda Ursell, Mary Nightingale, Derek Hodgson, Danillo Milic, Colm Murphy, John Jay, Christopher Somerville, Duncan Grove, V D, Frank Whitford, Ravi Shastri, Ivo Tennant, Neil Marinson, Alex Todorovic, Ferdinand Mount, Sally Payne, David Smith, John Harlow Social Affairs Editor, Lucy Irvine, Melanie Phillips, Nick Pitt, Frederic Raphael, Mrs P Vimber, Neil Wormald, Andrew Sullivan, Clive Davis, Stephen Grey, Simon Munnery, Dr Roger Henderson, Paul Nuki Nuki, Gavin Ames, Jan Battles, Diana Horsley, Simon Wilde, Tony Allen-Mills, Robert Sandall, Martin James, Eleanor Mills, Anthony Sattin, Robert Winnett, Irwin Stelzer, Terry Birch, Tom English, Robert Hewison, Roger Anderson, David Dougill, Martin Bradley, Pat Rowley, John Evans, Jane Bird, Thrasy Petropoulos, William Empson, Marian Martin, David Hewson, Susan Heathcote, David Puttnam, Tania Alexander, Margaret Coles, Jonathon Carr-Brown, Hugh Canning, Nigel Williams, Graham Duffill, Jeremy Clarkson, Edward Porter, Stewart Lee, Louise Taylor, Michael Portillo, Bob Walker, Jenny Shields, Denni Baden Howard, N A A, George Perry, John Cassidy, Robin Marlar, Graham Otway, Hugh McManners Defence Correspondent, Eliza Carthy, Tony Blair, Nick Gardner, Shelley von Strunckel, Peter Parker, Phillip Oppenheim, S Labovitch, Josephine Smit, Paul Donovan, Rev Peter Boulton-Lea, Richard Evan, Lynn Eaton, Steve Waugh, Lady Thatcher, Sue Lawrence, Quentien Wilson, William La Chenal, Sameer Abedi, Smita Talati, Paul Driver, Derek Clements, Michael Woodhead, M C, Garth Pearce, Zoë Smith, Nicholas Hellen, Richard Brooks, Maeve Sheehan, John Follain, Peter Windsor, Ian Hawkey, Nigel Williamson, Christopher Morgan, David Leppard, C Penny, Alicia Wyllie, Richard Girling, Mark Edwards, Steve Farrar Science Correspondent, Kirstie Hamilton, Tom Shone, Angus Mewse, Susan Clark, Phillip Kingsley The leading trichologist, Eben Black Chief Political Correspondent, Norman Sherry, Dr Death, Laurence Warner, Celia Brayfield, James Fox, Amy Kramer, Adam Hart-Davis, Adrienne Burgess, Christina Lamb, Victoria O'Brien, Jennifer Asiama, Thomas Harris, Sue Reid, Gillian Anderson, Raymond Keene, Douglas Alexander, Marie Colvin, Diana Wright, Jim Smith, N B, Margaret Forster, Vincent Cartwright, Helen Hawkins, Chris Partridge, Stephen Jones, Alfred Hitchcock, Richard Evans, Uzi Mahnaimi, M Diddams, Michael Wright, Andrew Neil, Zoé Linkson, Claire Oldfield, Miranda Seymour, David Walsh, John Hogley, Lance Klusener, John Stern, Ray Monk, Bryan Appleyard, Lois Rogers Medical Correspondent, Stephen Armstrong, Paul Cooper, Paul Bray, Christopher Goodwin, Sir Richard Evans, Josh Salzmann, Mark Prigg, R W Johnson, John Wright, Richard Woods, Kenneth Ellison Davis, Garth Alexander, Roger, H S R, Maurice Chittenden, Alex Fortune, Kevin Pratt, Jeremy Shuttleworth, Richard Brooks Arts Editor, James Dear, Colin Price, Andrew Lorenz Business Editor, Judith O'Reilly, Mark Franchetti, Jonathan Powell, Ray Hutton, Jon Ungoed-Thomas, Colin Browne, Andrew Rogers, Edward Parter, Neeraj Mishra, Ricky Dalton, Tara Palmer-Tomkinson, M E, Clifford D Jakes, Michael Sheridan, Mrs A J C, Sean Hargrave, Meeve Sheehan, Peter Neville-Hadley, Anna Ryder-Richardson, Brian Smyth, Matthew Lynn, Godfrey Smith, Paul Wallace, Rose Aidin, John Waples, Hunter Davies, A A Gill, Juliet Terzieff, David Hewsan, Matthew Campbell, Brian Glanville, Andrew Balley, David Sumner Smith, Chrissy Iley, Robert Johnston, Stephen Pettitt, John Inverdale, Kevin Goldstein-Jackson, Graham Porter, Sally Kinnes, Andrew Lorenz, Naomi Caine, Adrian Levy, David Wickers, Tom Rhodes, Christine Ross, Mata Hari, Nick Gardner Deputy Money Editor, David Gleeson, Mark Hodson, Nicholas Hellen Media Correspondent, Jonathan Futrell, J Newsome, Rupert Steiner, David Duckovny, Hugh Pearman, Dan Cairns, Jane Howard, Michael Evans, Sumit Das Gupta, David Parsley, Stephen Gray, R K, Marian Philips, David Smith Economics Editor, Richard Whiteley, Angie Newson, Anthony Howard, Sharon Krum, Roy Penrose Director General, Carey Scott, Jonathan Aitken, Floella Benjamin, India Knight, Walter Ellis, Joanna Simon, Kingston Smith, Simon Howard, Sarah Wynter, Juliet Butler, Dominic Midgley, Boris Schapiro, Karen Robinson,
... Women's World Cup, David Walsh talks to Kristine Lilly of the United States, the host nation ... white on the night. We take sun-shy Liv Tyler, Madonna and Drew Barrymore and see how ...
1999 - Gale Group | Sunday Times HA GDA
Tone Katla, Trond Møretrø, I. Sveen, Inga Marie Aasen, Lars Axelsson, Liv Marit Rørvik, Kristine Naterstad,
Journal Article Inhibition of Listeria monocytogenes in chicken cold cuts by addition of sakacin P and sakacin P‐producing Lactobacillus sakei Get access T. Katla, T. Katla Matforsk, Norwegian Food Research Institute, Ås, NorwayThe Norwegian School of Veterinary Science, Oslo, Norway Search for other works by this author on: Oxford Academic Google Scholar T. Møretrø, T. Møretrø Matforsk, Norwegian Food Research Institute, Ås, Norway Search for other works by this author on: Oxford Academic Google ...
Tópico(s): Microbial Metabolism and Applications
2002 - Oxford University Press | Journal of Applied Microbiology
Kristin Kaasen Jørgensen, Inge Christoffer Olsen, Guro Løvik Goll, M Lorentzen, Nils Bolstad, Espen A. Haavardsholm, Knut E.A. Lundin, Cato Mørk, Jørgen Jahnsen, Tore K Kvien, Ingrid Prytz Berset, Bjørg TS Fevang, Jon Florholmen, S. Kalstad, N.J. Mørk, K Ryggen, Kåre Steinar Tveit, Sigrun K Sæther, Bjørn Gulbrandsen, Jon Hagfors, Kenneth Waksvik, David J. Warren, Karoline J. Henanger, Øivind Asak, Somyeh Baigh, Ingrid Marianne Blomgren, Trude Jannecke Bruun, Katrine Dvergsnes, Svein Oskar Frigstad, Clara Gram Gjesdal, Berit Grandaunet, Inger Marie Jensen Hansen, Ingvild S H Hatten, Gert Huppertz‐Hauss, Magne Henriksen, Sunniva S Hoie, Jan Krogh, Julia R Kruse, Maud-Kristine Aga Ljoså, Irina Petrovna Midtgard, Paweł Mielnik, Bjørn Moum, Geir Noraberg, Armin Poyan, Ulf Prestegård, Haroon Rashid, Jan Henrik Rydning, Liv Sagatun, Kathrine Aglen Seeberg, Kristine Skjetne, Eldri Kveine Strand, Hilde Stray, Njaal Stray, Roald Torp, Cecilia Vold, Carl Magnus Ystrøm, Camilla Zettel,
Background TNF inhibitors have improved treatment of Crohn's disease, ulcerative colitis, spondyloarthritis, rheumatoid arthritis, psoriatic arthritis, and chronic plaque psoriasis, but are expensive therapies. The aim of NOR-SWITCH was to examine switching from originator infliximab to the less expensive biosimilar CT-P13 regarding efficacy, safety, and immunogenicity. Methods The study is a randomised, non-inferiority, double-blind, phase 4 trial with 52 weeks of follow-up. Adult patients on stable ...
Tópico(s): Health and Medical Research Impacts
2017 - Elsevier BV | The Lancet
Ida-Kristin Orjasaeter Elvsaas, Liv Giske, Brynjar Fure, Lene Kristine Juvet,
Background . Treatment of childhood obesity is important in preventing development of obesity-related diseases later in life. This systematic review evaluates the effect of multicomponent lifestyle interventions for children and adolescents from 2 to 18 years. Methods and Results . We performed systematic searches in nine databases. Thirty-nine studies met the criteria for meta-analyses. We found a significant difference in body mass index (BMI) after 6 months (MD −0.99 (95% CI −1.36 to −0.61)), 12 months ( ...
Tópico(s): Child Nutrition and Feeding Issues
2017 - Hindawi Publishing Corporation | Journal of Obesity
Åslaug Helland, Hege G. Russnes, Gro Live Fagereng, Khalid Al‐Shibli, Yvonne Andersson, Thomas Berg, Line Bjørge, Egil Støre Blix, Bodil Bjerkehagen, Sigmund Brabrand, Marte Grønlie Cameron, Astrid Dalhaug, Dalia Dietzel, Tom Dønnem, Espen Enerly, Åsmund Flobak, Sverre Fluge, Bjørnar Gilje, Bjørn Tore Gjertsen, Bjørn Henning Grønberg, Kari Grønås, Tormod K. Guren, Hanne Hamre, Åse Haug, Daniel Heinrich, Geir Olav Hjortland, Eivind Hovig, Randi Hovland, Ann‐Charlotte Iversen, Emiel A. M. Janssen, Jon Amund Kyte, Hedda von der Lippe Gythfeldt, Ragnhild A. Lothe, Jo‐Åsmund Lund, Leonardo A. Meza‐Zepeda, Monica Cheng Munthe‐Kaas, Olav Toai Duc Nguyen, Pitt Niehusmann, Hilde Nilsen, Katarina Puco, Anne Hansen Ree, Tonje Bøyum Riste, Karin Semb, Eli Sihn Samdal Steinskog, Andreas Stensvold, Pål Suhrke, Øyvind Tennøe, Geir E. Tjønnfjord, Liv Jorunn Vassbotn, Eline Aas, Kristine Aasebø, Kjetil Taskén, Sigbjørn Smeland,
Abstract Background Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed attention has arisen due to recent advancements in cancer diagnostics including access to high-throughput sequencing of tumour tissue. Targeted therapies interfering with cancer specific pathways have been developed and approved for subgroups of patients. These drugs might ...
Tópico(s): Colorectal Cancer Treatments and Studies
2022 - BioMed Central | Journal of Translational Medicine
Tonje S. Steigedal, Torunn Bruland, Kristine Misund, Liv Thommesen, Astrid Lægreid,
The gastric hormone gastrin and its precursors promote proliferation in several gastrointestinal cell types. Here we show that gastrin induces transcription of cell cycle gene cyclin D1 and protooncogene c-fos in the neuroendocrine pancreatic cell line AR42J and that this gastrin response is inhibited by endogenous inducible cAMP early repressor (ICER). The transcriptional repressor ICER is known to downregulate both its own expression and the expression of other genes containing cAMP-responsive ...
Tópico(s): Digestive system and related health
2006 - American Physiological Society | AJP Gastrointestinal and Liver Physiology
Kristin Lie Romm, Liv Nilsen, Kristine Gjermundsen, Marit Holter, A. Fjell, Ingrid Melle, Arne Repål, Fiona Lobban,
Background A reduced availability of resources has hampered the implementation of family work in psychosis. Web-based support programs have the potential to increase access to high-quality, standardized resources. This pilot study tested the Norwegian version of the Relatives Education and Coping Toolkit (REACT), a web-based United Kingdom National Health Service program in combination with phone-based support by trained family therapists. Objective We investigated how the program was perceived by ...
Tópico(s): Mental Health Treatment and Access
2020 - JMIR Publications | JMIR Mental Health
Heidi A. Zangi, Petter Mowinckel, Arnstein Finset, Liv Rognerud Eriksson, Turid Ø. Høystad, Anne Kristine Lunde, Kåre Birger Hagen,
Objective To evaluate the effects of a mindfulness-based group intervention, the Vitality Training Programme (VTP), in adults with inflammatory rheumatic joint diseases. Methods In a randomised controlled trial, the VTP—a 10-session mindfulness-based group intervention including a booster session after 6 months—was compared with a control group that received routine care plus a CD for voluntary use with mindfulness-based home exercises. The primary outcome was psychological distress measured by the General ...
Tópico(s): Psychosomatic Disorders and Their Treatments
2011 - BMJ | Annals of the Rheumatic Diseases
Marit Ulvik, Helene Marie Kjærgård Eide, Liv Eide, Ingrid Helleve, Vigdis Stokker Jensen, Kristine Ludvigsen, Dag Roness, Lars Petter Storm Torjussen,
The current study is a collective self-study on how we as 15 teacher educators at a university in Norway tried to improve our teaching through working with cases with the aim of better supporting student teachers in making links between theory and practice. We wanted to address the common criticism in teacher education concerning a perceived gap between practice and theory. Our presupposition was that one way to prepare student teachers for work and bring together theoretical and practical knowledge ...
Tópico(s): Educator Training and Historical Pedagogy
2020 - Taylor & Francis | Professional Development in Education
Lærke Stewart, Inger Greve Alsos, Christian Bay, Amy Breen, Christian Brochmann, Noémie Boulanger‐Lapointe, Olivier Broennimann, Helga Bültmann, Peder Klith Bøcher, Christian Damgaard, Fred J.A. Daniëls, Dorothée Ehrich, Pernille Bronken Eidesen, Antoine Guisan, Ingibjörg S. Jónsdóttir, Jonathan Lenoir, Peter C. le Roux, Esther Lévesque, Miska Luoto, Jacob Nabe‐Nielsen, Peter Schönswetter, Andreas Tribsch, Liv Unn Tveraabak, Risto Virtanen, Donald A. Walker, Kristine Bakke Westergaard, Nigel G. Yoccoz, Jens‐Christian Svenning, Mary S. Wisz, Niels Martin Schmidt, Loïc Pellissier,
Abstract Aim The A rctic has experienced marked climatic differences between glacial and interglacial periods and is now subject to a rapidly warming climate. Knowledge of the effects of historical processes on current patterns of diversity may aid predictions of the responses of vegetation to future climate change. We aim to test whether plant species and genetic diversity patterns are correlated with time since deglaciation at regional and local scales. We also investigate whether species richness ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2016 - Wiley | Global Ecology and Biogeography
Kristine Gismervik, Torkjel Bruheim, Liv Marit Rørvik, Solveig Haukeland, Ida Skaar,
Norwegian meadows, including those for silage production, are recently found heavily invaded by the slug Arion vulgaris in exposed areas. As a consequence, large numbers of slugs might contaminate grass silage and cause a possible threat to animal feed quality and safety. It is well known that silage contaminated by mammalian or avian carcasses can lead to severe outbreaks of botulism among livestock. Invertebrates, especially fly-larvae (Diptera), are considered important in the transfer of Clostridium ...
Tópico(s): Plant and fungal interactions
2014 - BioMed Central | Acta veterinaria Scandinavica
Kristine Gismervik, Marina Aspholm, Liv Marit Rørvik, Torkjel Bruheim, Anders Andersen, Ida Skaar,
Listeriosis is a frequent silage-associated disease in ruminants. The slugs Arion vulgaris are invaders in gardens, vegetable crops and meadows for silage production. Field and laboratory studies were conducted to clarify whether slugs could host Listeria monocytogenes and thereby constitute a threat to animal feed safety.Selective culture of L. monocytogenes from 79 pooled slug samples (710 slugs) resulted in 43% positive, 16% with mean L. monocytogenes values of 405 CFU g(-1) slug tissues. Of 62 ...
Tópico(s): Animal Ecology and Behavior Studies
2015 - Oxford University Press | Journal of Applied Microbiology
Xiaozi Liu, Endre Tvinnereim, Kristine Grimsrud, Henrik Lindhjem, Liv Guri Velle, Heidi Iren Saure, Hanna Lee,
We conducted a national survey on a high-quality internet panel to study landscape preferences in Norway, using photos as stimuli. We examined preference heterogeneity with respect to socio-demographic characteristics and latent topics brought up by the respondents, using ordinal logistic regression and structural topic modelling (STM), a machine learning-based analysis. We found that pasture landscapes are the most favoured (55%), while densely planted spruce forests are the least favoured (8%). The ...
Tópico(s): Economic and Environmental Valuation
2021 - Taylor & Francis | Landscape Research
Randi Larsen Indrevær, Kristine Lillebø Holm, Pål Aukrust, Liv Osnes, Elin Hallan Naderi, Børre Fevang, Heidi Kiil Blomhoff,
Abstract Common variable immunodeficiency (CVID) is a disease that is characterized primarily by low levels of serum Igs, resulting in a high incidence of infections. It also has been associated with impaired B cell signaling via TLR9 and reduced serum levels of vitamin A. Given the established link between vitamin A deficiency and increased susceptibility to infections, we investigated the ability of the vitamin A metabolite all-trans retinoic acid (RA) to restore the defective immune responses in ...
Tópico(s): Immune Cell Function and Interaction
2013 - American Association of Immunologists | The Journal of Immunology
Melissa R. Balthasar, Mathieu Roelants, Bente Brannsether‐Ellingsen, Ragnar Bjarnason, Ingunn Holden Bergh, Liv Grimstvedt Kvalvik, Kristine Marie Stangenes, Astanand Jugessur, Mette Christophersen Tollånes, Finn Markussen, Pétur Benedikt Júlíusson,
Trends in childhood overweight, obesity and severe obesity have been lacking in Norway. This study assessed pre-pandemic trends from 2010 to 2019 and evaluated differences in prevalence during the 2020-2022 pandemic years.
Tópico(s): Global Public Health Policies and Epidemiology
2024 - Wiley | Acta Paediatrica
Kristine Misund, Tonje S. Steigedal, Astrid Lægreid, Liv Thommesen,
Abstract Inducible cAMP early repressor (ICER) splice variants are generated upon activation of an alternative, intronic promoter within the CREM gene. ICER is proposed to downregulate both its own expression, and the expression of other genes, containing cAMP‐responsive promoter elements. To examine the biological function of the two ICER splice variants, I and IIγ, in comparable cellular systems, we generated HEK 293 cell variants with controllable overexpression of either ICER I or IIγ. These ...
Tópico(s): RNA regulation and disease
2007 - Wiley | Journal of Cellular Biochemistry
Linn-Karina Myrland Selvik, Shalini V. Rao, Tonje S. Steigedal, Ildri Haltbakk, Kristine Misund, Torunn Bruland, Wenche S. Prestvik, Astrid Lægreid, Liv Thommesen,
Salt-inducible kinase 1 (SIK1/Snf1lk) belongs to the AMP-activated protein kinase (AMPK) family of kinases, all of which play major roles in regulating metabolism and cell growth. Recent studies have shown that reduced levels of SIK1 are associated with poor outcome in cancers, and that this involves an invasive cellular phenotype with increased metastatic potential. However, the molecular mechanism(s) regulated by SIK1 in cancer cells is not well explored. The peptide hormone gastrin regulates cellular ...
Tópico(s): Pancreatic function and diabetes
2014 - Public Library of Science | PLoS ONE
Kristine Gismervik, Å.T. Randby, Liv Marit Rørvik, Torkjel Bruheim, Arild Andersen, Marta Hernández, Ida Skaar,
Abstract This study aimed to explore how invasive slug populations of Arion vulgaris influenced the microbiological quality and animal feed safety of grass silage, and the efficiency of silage additives and wilting to control the microbiology of slug contaminated crops. The effect of four slug contamination levels, including control, of a grass crop harvested for silage production, was evaluated in laboratory scale. The crop was wilted to two dry matter (DM) levels: low (253 g DM/kg) and high (372 ...
Tópico(s): Forensic Entomology and Diptera Studies
2014 - Elsevier BV | Animal Feed Science and Technology
Phoi Phoi Diep, Corina S. Rueegg, Marta Maria Burman, Lorentz Brinch, Kristine Bø, Kristian Fosså, Linn Landrø, Jon Håvard Loge, May Brit Lund, Richard J. Massey, Ole Henrik Myrdal, Meeta Pathak, Liv Rimstad, Kristine Eidal Tanem, Geir E. Tjønnfjord, Trond Mogens Aaløkken, Ellen Ruud,
Purpose: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an established treatment predominantly for malignancies. Chronic graft-versus-host disease (cGVHD) is the leading long-term complication after allo-HSCT, but knowledge on cGVHD and health-related quality of life (HRQOL) in long-term survivors of allo-HSCT performed in childhood, adolescence, and young adulthood (CAYA) is scarce. Therefore, we aimed to (1) assess prevalence and risk factors of active cGVHD using the 2014 National ...
Tópico(s): Acute Lymphoblastic Leukemia research
2022 - Mary Ann Liebert, Inc. | Journal of Adolescent and Young Adult Oncology
Madalene A. Earp, Jonathan P. Tyrer, Stacey J. Winham, Hui‐Yi Lin, Ganna Chornokur, Joe Dennis, Katja K.H. Aben, Hoda Anton‐Culver, Natalia Antonenkova, Elisa V. Bandera, Yukie T. Bean, Matthias W. Beckmann, Line Bjørge, Natalia Bogdanova, Louise A. Brinton, Angela Brooks‐Wilson, Fiona Bruinsma, Clareann H. Bunker, Ralf Bützow, Ian Campbell, Karen Carty, Jenny Chang‐Claude, Linda S. Cook, Daniel W. Cramer, Julie M. Cunningham, Cezary Cybulski, Agnieszka Dansonka‐Mieszkowska, Evelyn Despierre, Jennifer A. Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Douglas F. Easton, Diana Eccles, Robert P. Edwards, Arif B. Ekici, Peter A. Fasching, Brooke L. Fridley, Aleksandra Gentry‐Maharaj, Graham G. Giles, Rosalind Glasspool, Marc T. Goodman, Jacek Gronwald, Philipp Harter, Alexander Hein, Florian Heitz, Michelle A.T. Hildebrandt, Peter Hillemanns, Claus Høgdall, Estrid Høgdall, Satoyo Hosono, Edwin S. Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Audrey Jung, Beth Y. Karlan, Melissa Kellar, Lambertus A. Kiemeney, Boon Kiong Lim, Susanne K. Kjær, Camilla Krakstad, Jolanta Kupryjańczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Shashi Lele, Jenny Lester, Douglas A. Levine, Zheng Li, Dong Liang, Jolanta Lissowska, Karen H. Lu, Jan Lubiński, Lene Lundvall, Leon F.A.G. Massuger, Keitaro Matsuo, Valerie McGuire, Esther M. John, Iain A. McNeish, Usha Menon, Roger L. Milne, Francesmary Modugno, Kirsten B. Moysich, Roberta B. Ness, Heli Nevanlinna, Kunle Odunsi, Sara H. Olson, Irene Orlow, Sandra Oršulić, James Paul, Tanja Pejović, Liisa M. Pelttari, Jenny B. Permuth, Malcolm C. Pike, Elizabeth M. Poole, Barry P. Rosen, Mary Anne Rossing, Joseph H. Rothstein, Ingo B. Runnebaum, Iwona K. Rzepecka, Eva Schernhammer, Ira Schwaab, Xiao‐Ou Shu, Yurii B. Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C. Southey, Beata Śpiewankiewicz, Lara Sucheston‐Campbell, Ingvild L. Tangen, Soo‐Hwang Teo, Kathryn L. Terry, Pamela J. Thompson, Lotte Thomsen, Shelley S. Tworoger, Anne M. van Altena, Ignace Vergote, Liv Cecilie Vestrheim Thomsen, Robert A. Vierkant, Christine Walsh, Shan Wang‐Gohrke, Nicolas Wentzensen, Alice S. Whittemore, Kristine G. Wicklund, Lynne R. Wilkens, Yin Ling Woo, Anna H. Wu, Xifeng Wu, Yong-Bing Xiang, Hannah Yang, Wei Zheng, Argyrios Ziogas, Alice W. Lee, Celeste Leigh Pearce, Andrew Berchuck, Joellen M. Schildkraut, Susan J. Ramus, Álvaro N.A. Monteiro, Steven A. Narod, Thomas A. Sellers, Simon A. Gayther, Linda E. Kelemen, Georgia Chenevix‐Trench, Harvey A. Risch, Paul D.P. Pharoah, Ellen L. Goode, Catherine M. Phelan,
Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer mortality in American women. Normal ovarian physiology is intricately connected to small GTP binding proteins of the Ras superfamily (Ras, Rho, Rab, Arf, and Ran) which govern processes such as signal transduction, cell proliferation, cell motility, and vesicle transport. We hypothesized that common germline variation in genes encoding small GTPases is associated with EOC risk. We investigated 322 variants in 88 small GTPase genes ...
Tópico(s): Ovarian cancer diagnosis and treatment
2018 - Public Library of Science | PLoS ONE
M.R. Mirza, Luka Tandarić, J R Henriksen, Juhani Mäenpää, René dePont Christensen, Marianne Waldstrøm, K Lindemann, Henrik Roed, Annika Auranen, L A Akslen, Liv Cecilie Vestrheim Thomsen, soeren Lindberg, Kristine S. Madsen, Line Bjørge,
In patients with epithelial ovarian cancer (EOC), the clinical efficacy of monotherapy with immune checkpoint inhibitors (ICIs) against PD-1/PD-L1 is modest. To enhance response rates to these immunotherapeutic agents and broaden the indications for their use, new approaches involving combinational therapy are needed. The immune regulator CD73 is a potential target, as it promotes tumor escape by producing immunosuppressive extracellular adenosine in the tumor microenvironment. Here, we present the ...
Tópico(s): Immune cells in cancer
2024 - Elsevier BV | Gynecologic Oncology
Elling Kvamme, Kristine Bach Korsholm Knudsen, Liv Sund,
Tópico(s): Cancer, Hypoxia, and Metabolism
1962 - Taylor & Francis | Scandinavian Journal of Clinical and Laboratory Investigation
Line Barington, Liv von Voss Christensen, Kristian Kåber Pedersen, Kristine Niss Arfelt, Martin Roumain, Kristian H. R. Jensen, Viktoria M. S. Kjær, Viktorija Daugvilaite, John F. Kearney, Jan Pravsgaard Christensen, Gertrud M. Hjortø, Giulio G. Muccioli, Peter Johannes Holst, Mette M. Rosenkilde,
B1 cells constitute a specialized subset of B cells, best characterized in mice, which is abundant in body cavities, including the peritoneal cavity. Through natural and antigen-induced antibody production, B1 cells participate in the early defense against bacteria. The G protein-coupled receptor 183 (GPR183), also known as Epstein-Barr virus-induced gene 2 (EBI2), is an oxysterol-activated chemotactic receptor that regulates migration of B cells. We investigated the role of GPR183 in B1 cells in ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2022 - Multidisciplinary Digital Publishing Institute | Cells
Linn-Karina Myrland Selvik, Christina S. Fjeldbo, Arnar Flatberg, Tonje S. Steigedal, Kristine Misund, Endre Anderssen, Berit Doseth, Mette Langaas, Sushil Tripathi, Vidar Beisvåg, Astrid Lægreid, Liv Thommesen, Torunn Bruland,
Abstract Background How cells decipher the duration of an external signal into different transcriptional outcomes is poorly understood. The hormone gastrin can promote a variety of cellular responses including proliferation, differentiation, migration and anti-apoptosis. While gastrin in normal concentrations has important physiological functions in the gastrointestine, prolonged high levels of gastrin (hypergastrinemia) is related to pathophysiological processes. Results We have used genome-wide ...
Tópico(s): Pancreatic function and diabetes
2013 - BioMed Central | BMC Genomics
Christina S. Fjeldbo, Kristine Misund, Clara‐Cecilie Günther, Mette Langaas, Tonje S. Steigedal, Liv Thommesen, Astrid Lægreid, Torunn Bruland,
Transfected cell microarray is a promising method for accelerating the functional exploration of the genome, giving information about protein function in the living cell.The microarrays consist of clusters of cells (spots) overexpressing or silencing a particular gene product.The subsequent analysis of the phenotypic consequences of such perturbations can then be detected using cell-based assays.The focus in the present study was to establish an experimental design and a robust analysis approach ...
Tópico(s): Advanced Biosensing Techniques and Applications
2008 - Oxford University Press | Nucleic Acids Research
Crystal Lee, Mark Woodward, G. David Batty, Alexa S. Beiser, Steven Bell, Claudine Berr, Espen Bjertness, John Chalmers, Robert Clarke, Jean‐François Dartigues, Kendra Davis‐Plourde, Stéphanie Debette, Emanuele Di Angelantonio, Catherine Féart, Ruth Frikke‐Schmidt, John Gregson, Mary N. Haan, Linda B. Hassing, Kathleen M. Hayden, Marieke P. Hoevenaar‐Blom, Jaakko Kaprio, Mika Kivimäki, Georgios Lappas, Eric B. Larson, Erin S. LeBlanc, Anne Lee, Li‐Yung Lui, Eric P. Moll van Charante, Toshiharu Ninomiya, Liv Tybjærg Nordestgaard, Tomoyuki Ohara, Toshiaki Ohkuma, Teemu Palviainen, Karine Pérès, Ruth Peters, Nawab Qizilbash, Edo Richard, Annika Rosengren, Sudha Seshadri, M. Shipley, Archana Singh‐Manoux, Bjørn Heine Strand, Willem A. van Gool, Eero Vuoksimaa, Kristine Yaffe, Rachel Huxley,
Summary Uncertainty exists regarding the relation of body size and weight change with dementia risk. As populations continue to age and the global obesity epidemic shows no sign of waning, reliable quantification of such associations is important. We examined the relationship of body mass index, waist circumference, and annual percent weight change with risk of dementia and its subtypes by pooling data from 19 prospective cohort studies and four clinical trials using meta‐analysis. Compared with ...
Tópico(s): Dementia and Cognitive Impairment Research
2020 - Wiley | Obesity Reviews
Per Magnus, Charlotte Birke, Kristine Vejrup, A. Haugan, Elin R. Alsaker, Anne Kjersti Daltveit, Marte Handal, Margaretha Haugen, Gudrun Høiseth, Gun Peggy Knudsen, Liv Paltiel, Patricia Schreuder, Kristian Tambs, Line Vold, Camilla Stoltenberg,
This is an update of the Norwegian Mother and Child Cohort Study (MoBa) cohort profile which was published in 2006. Pregnant women attending a routine ultrasound examination were initially invited. The first child was born in October 1999 and the last in July 2009. The participation rate was 41%. The cohort includes more than 114 000 children, 95 000 mothers and 75 000 fathers. About 1900 pairs of twins have been born. There are approximately 16 400 women who participate with more than one pregnancy. ...
Tópico(s): Health disparities and outcomes
2016 - Oxford University Press | International Journal of Epidemiology
Urs B. Hagemann, Else-Marie Hagelin, Katrine Wickstroem, Kristine Sponheim, Roger Smeets, Jenny Karlsson, Roger M. Bjerke, Mari I. Suominen, Yvonne Konkol, Jenni Bernoulli, Jukka P. Rissanen, Jussi M. Halleen, Liv-Ingrid Oedegaardstuen, Alan Cuthbertson,
... Urs B. Hagemann, Else-Marie Hagelin, Katrine Wickstroem, Kristine Sponheim, Roger Smeets, Jenny Karlsson, Roger M. Bjerke, Mari I. Suominen, Yvonne Konkol, Jenni Bernoulli, Jukka Rissanen, Jussi Halleen, Liv-Ingrid Oedegaardstuen, Alan Cuthbertson. A novel high energy ...
Tópico(s): Occupational and environmental lung diseases
2016 - American Association for Cancer Research | Cancer Research
Kristine Birkeli, Ragnhild Gya, Siri Vatsø Haugum, Liv Guri Velle, Vigdis Vandvik,
The coastal heathlands of Northwest Europe are highly valued cultural landscapes, that are critically endangered due to land use and climatic changes, such as increased frequency and severity of drought events. Our study is the first to assess how the germination and early seedling growth of Calluna vulgaris respond to drought. In a factorial design field experiment, we exposed maternal plants to three in-situ drought treatments (control, 60%, 90% roof coverage), across three successional stages ...
Tópico(s): Seed Germination and Physiology
2023 - Wiley | Ecology and Evolution
Jyothi Tirumalasetty, Liv Sullivan, Kristine Martinez, William Collins, Marleni Albarran, Pooja Gajare, Laurie Kost, R. Sharon Chinthrajah, Sayantani Sindher, Shu Cao,
The safety and efficacy of food oral immunotherapy (OIT) has been extensively studied, however long-term maintenance OIT studies are limited. To better understand the durability of OIT long-term, larger studies on compliance, quality of life (QOL), and burden of treatment (BOT) are needed. Participants and caregivers who participated in food OIT clinical trials at Stanford University completed three IRB approved surveys: food allergy long-term follow up questionnaire (FALTFU), food allergy quality of ...
Tópico(s): Education and Learning Interventions
2023 - Elsevier BV | Journal of Allergy and Clinical Immunology