
Márcia Noya-Rabelo, Carolina Thé Macêdo, Ticiana Ferreira Larocca, Admilson Machado, Thais Pacheco, Jorge Andion Torreão, Bruno Solano de Freitas Souza, Milena Botelho Pereira Soares, Ricardo Ribeiro‐dos‐Santos, Luís Cláudio Lemos Correia,
Previous data has shown that patients in the indeterminate form of Chagas disease may present myocardial fibrosis as shown on through magnetic resonance imaging (MRI). However, there is little information available regarding the degree of severity of myocardial fibrosis in these individuals. This variable has the potential to predict the evolution of Chagas' disease into its cardiac form.To describe the frequency and extent of myocardial fibrosis evaluated using an MRI in patients in the indeterminate ...
Tópico(s): Viral Infections and Immunology Research
2018 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Vítor Sencadas, Carlos M. Costa, Gabriela Botelho, Cristina Caparrós, Clarisse Ribeiro, José Luís Gómez Ribelles, S. Lanceros‐Méndez,
Poly(lactic acid) (PLA) electrospun membranes were obtained by electrospinning and characterized by scanning electron microscopy (SEM) and thermal analysis. The polymer membranes showed a random fiber distribution with a mean diameter of 1 μm (±300 nm). Differential scanning calorimetry (DSC) experiments showed that the membranes had a glass transition, cold crystallization, and melting temperatures of 54, 90, and 151°C, respectively. The kinetic study of thermal degradation of PLA under a nitrogen atmosphere ...
Tópico(s): Nanocomposite Films for Food Packaging
2011 - Taylor & Francis | Journal of Macromolecular Science Part B
Daniela M. Correia, Renato Gonçalves, Clarisse Ribeiro, Vítor Sencadas, Gabriela Botelho, José Luís Gómez Ribelles, S. Lanceros‐Méndez,
Poly(vinylidene fluoride) microparticles with diameters between 0.80 and 5.50 μm were produced. Cell viability shows their suitability for tissue engineering.
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2014 - Royal Society of Chemistry | RSC Advances
Vítor Sencadas, Daniela M. Correia, Clarisse Ribeiro, Susana Moreira, Gabriela Botelho, José Luís Gómez Ribelles, S. Lanceros‐Méndez,
Chitosan fiber mats were successfully processed by electrospinning. The as-spun fiber mats were neutralized with ethanol and cross-linked with glutaraldehyde. A decrease of the fiber average diameter from 243 ± 43 nm down to 215.53 nm was observed for the neutralized and cross-linking chitosan membrane. It was found that the processing conditions do not alter the initial deacetylation degree of the polymer. Polymer crystallinity index showed a decrease from 61% for the Protasan material down to 17% ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2012 - Elsevier BV | Polymer Testing
J.C. Dias, Clarisse Ribeiro, Vítor Sencadas, Gabriela Botelho, José Luís Gómez Ribelles, S. Lanceros‐Méndez,
Hydrolytic degradation of electrospun mats of poly(l-lactic acid), PLLA, as a function of crystallinity and fiber diameter has been studied. The degradation in a saline phosphate buffer solution (PBS) up to 20 weeks produced a slight decrease in the sample mass but a clear decrease of the polymer average molecular weight in the amorphous fibers. This effect decreases as crystallinity increases. It is important for applications that morphological characteristics of the membranes such as average fiber ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2012 - Elsevier BV | Polymer Testing
Pedro Caldeira Abreu, Mohammadreza Bayat, A. Pascoal, João Botelho, Pedro M. P. Góis, Jorge Ribeiro, Miguel Ribeiro, Manuel Rufino, Luís Sebastião, Henrique Silva,
Abstract: Based on a companion publication that introduces the theoretical foundations, this paper describes the implemented architecture for formation control of the upper segment vehicles of the MORPH project. We highlight the necessary modifications and additional elements, mainly in terms of control and estimation, to allow for the implementation in real vehicles. We illustrate the performance of the system with results from sea trials in Lisbon and in the Azores, with a number of heterogeneous ...
Tópico(s): Opportunistic and Delay-Tolerant Networks
2015 - Elsevier BV | IFAC-PapersOnLine
Ana Rita Ribeiro, Carla Luís, Rúben Fernandes, Mónica C. Botelho,
There is increasing attention on the complex interactions occurring between schistosome parasites and their hosts. However, little is known about the occurrence, epidemiology, and mechanisms of schistosomiasis-associated infertility. In this article, we argue that an in-depth understanding of the interplay between parasites and the host endocrine system may significantly enhance current knowledge of infertility in infected individuals. We discuss the basic hormonal mechanisms that may lead to the ...
Tópico(s): Reproductive System and Pregnancy
2019 - Elsevier BV | Trends in Parasitology
Daniela M. Correia, Clarisse Ribeiro, José Carlos Ferreira, Gabriela Botelho, José Luís Gómez Ribelles, S. Lanceros‐Méndez, Vítor Sencadas,
Poly(hydroxybutyrate) (PHB) obtained from sugar cane waste was dissolved in a blend of chloroform and dimethylformamide (DMF) and electrospun at 40°C. By adding DMF to the solution, the electrospinning process for the PHB polymer becomes more stable, allowing complete polymer crystallization during the jet travelling between the tip and the grounded collector. The influence of processing parameters on fiber size and distribution was systematically studied. It was observed that an increase of tip inner ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2013 - Wiley | Polymer Engineering and Science

Tânia Gaspar, Manuela Faia Correia, Maria do Céu Machado, Miguel Xavier, Fábio Botelho Guedes, José Luís Pais Ribeiro, Margarida Gaspar de Matos,
sexo, idade e escolaridade na avaliação dos ambientes de trabalho.Considera-se o instrumento EATS e as respetivas escalas um instrumento que vem responder a uma necessidade das organizações para avaliar o ambiente de trabalho saudável numa perspetiva ecológica e permite a monitorização de medidas de promoção da saúde e prevenção dos riscos nas organizações com o objetivo central de melhorar o bem-estar e saúde dos trabalhadores, organizações e a sociedade como um todo.
Tópico(s): Healthcare and Environmental Waste Management
2022 - Sociedade Portuguesa de Psicologia da Saúde | Psicologia Saúde & Doenças
Anabela Silva‐Fernandes, Maria do Carmo Costa, Sara Duarte‐Silva, Pedro Oliveira, Cláudia Botelho, Luís Martins, José Mariz, Tiago Ferreira, Filipa Pinto‐Ribeiro, Margarida Correia‐Neves, Cristina Costa, Patrı́cia Maciel,
Machado–Joseph disease (MJD) is a late-onset neurodegenerative disorder caused by a polyglutamine (polyQ) expansion in the ataxin-3 protein. We generated two transgenic mouse lineages expressing the expanded human ataxin-3 under the control of the CMV promoter: CMVMJD83 and CMVMJD94, carrying Q83 and Q94 stretches, respectively. Behavioral analysis revealed that the CMVMJD94 transgenic mice developed motor uncoordination, intergenerational instability of the CAG repeat and a tissue-specific increase ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2010 - Elsevier BV | Neurobiology of Disease

Márcia Noya-Rabelo, Ticiana Ferreira Larocca, Carolina Thé Macêdo, Jorge Andion Torreão, Bruno Solano de Freitas Souza, Juliana Fraga Vasconcelos, Luciana Estrella Souza, Agnaluce Moreira Silva, Ricardo Ribeiro dos Santos, Luís Cláudio Lemos Correia, Milena Botelho Pereira Soares,
<b><i>Objectives:</i></b> Chagas cardiomyopathy has worse long-term outcomes than other cardiomyopathies. A biomarker strategy to refer subjects for noninvasive cardiac imaging may help in the early identification of cardiac damage in subjects with Chagas disease. Galectin-3 (Gal-3) is a mediator of cardiac fibrosis shown to be upregulated in animal models of decompensated heart failure. Here we assessed the correlation of Gal-3 with myocardial fibrosis in patients with Chagas ...
Tópico(s): Cardiomyopathy and Myosin Studies
2016 - Karger Publishers | Cardiology
Daniela M. Correia, Clarisse Ribeiro, Vítor Sencadas, L. Vikingsson, M. Oliver Gasch, José Luís Gómez Ribelles, Gabriela Botelho, S. Lanceros‐Méndez,
Cell supports based on electroactive materials, that generate electrical signal variations as a response to mechanical deformations and vice-versa, are gaining increasing attention for tissue engineering applications. In particular, poly(vinylidene fluoride), PVDF, has been proven to be suitable for these applications in the form of films and two-dimensional membranes. In this work, several strategies have been implemented in order to develop PVDF three-dimensional scaffolds. Three processing methods, ...
Tópico(s): Advanced Materials and Mechanics
2015 - Elsevier BV | Materials & Design
Luís Amaro, Daniela M. Correia, Pedro M. Martins, Gabriela Botelho, Sónia A. C. Carabineiro, Clarisse Ribeiro, S. Lanceros‐Méndez,
Poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) is a piezoelectric biodegradable and biocompatible polymer suitable for tissue engineering applications. The incorporation of magnetostrictive cobalt ferrites (CFO) into PHBV matrix enables the production of magnetically responsive composites, which proved to be effective in the differentiation of a variety of cells and tissues. In this work, PHBV and PHBV with CFO nanoparticles were produced in the form of films, fibers and porous scaffolds and subjected ...
Tópico(s): Additive Manufacturing and 3D Printing Technologies
2020 - Multidisciplinary Digital Publishing Institute | Polymers

Luis Felipe de Paula Santos, Bruno Ribeiro, Luís Rogério de Oliveira Hein, Edson Cocchieri Botelho, Michelle Leali Costa,
In this work, nanostructured composites of polyetherimide (PEI) with addition of functionalized multiwall carbon nanotube (MWCNT) were processed via solution mixing. After processing, these nanocomposites were evaluated by thermogravimetry (TGA), dynamic-mechanical analysis (DMA), scanning electron microscopy (SEM) and atomic force microscopy (AFM). Subsequently, the nanocomposite was processed with carbon fibers by using hot compression molding. In order to evaluate interlaminar fracture strength, the ...
Tópico(s): Natural Fiber Reinforced Composites
2017 - IOP Publishing | Materials Research Express

Elaine Rossi Ribeiro, Ráisa Camilo Ferreira, Fábio Luís Montanari, Micnéias Tatiana de Souza Lacerda Botelho, Marisa Dibbern Lopes Correia, Érika Christiane Marocco Duran,
ABSTRACT Objective: to construct the conceptual and operational definitions of the defining and conceptual characteristics of the related factors of the nursing diagnosis (ND) hypothermia (00006) of NANDA-I, 2015-2017, in adult patients in the perioperative period. Method: an integrative literature review in the Medical Literature Analysis and Retrieval System Online, Cochrane Library, The Cumulative Index to Nursing and Allied Health Literature and in Latin & American Literature in Health Sciences ...
Tópico(s): Health Education and Validation
2021 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Liliana Reis, Luís Paiva, Marco Costa, Joana Silva, Rogério Teixeira, Ana Botelho, Paulo Dinis, Marta Madeira, Joana Maria Ribeiro, José Nascimento, Lino Gonçalves,
O encerramento percutâneo do apêndice auricular esquerdo (AAE) constitui uma terapêutica de interesse clínico nos doentes de alto risco de acidente vascular cerebral (AVC) e contraindicação para anticoagulação oral (ACO). A ecografia intracardíaca (ICE) pode tornar este procedimento exequível em doentes em que o ecocardiograma transesofágico (ETE) está desaconselhado. Os objetivos consistiram na avaliação da eficácia e segurança da técnica de encerramento do AAE e na avaliação da exequibilidade do ICE ...
Tópico(s): Cardiac Arrhythmias and Treatments
2018 - Elsevier BV | Revista Portuguesa de Cardiologia

Luis Felipe de Paula Santos, Bruno Ribeiro, Luís Rogério de Oliveira Hein, René Alderliesten, Dimitrios Zarouchas, Edson Cocchieri Botelho, Michelle Leali Costa,
Abstract This work concerns the fatigue behavior at three different temperature conditions (−40, 20, and 80°C) and the addition of multiwalled carbon nanotube (MWCNT) into a carbon‐fiber reinforced poly(ether‐imide) composite. The incorporation of MWCNT into the composite increased the tensile strength and Young's modulus by up 5 and 2%, respectively. At low temperature, the incorporation of the nanoparticles improved the fatigue strength of the laminates by 15%. The shear strength results obtained ...
Tópico(s): Tribology and Wear Analysis
2020 - Wiley | Journal of Applied Polymer Science
Liliana Reis, Luís Paiva, Marco Costa, Joana Silva, Rogério Teixeira, Ana Botelho, Paulo Dinis, Marta Madeira, Joana Maria Ribeiro, José Nascimento, Lino Gonçalves,
Percutaneous closure of the left atrial appendage (LAA) is a promising therapy in patients with atrial fibrillation with high risk for stroke and contraindication for oral anticoagulation (OAC). Intracardiac echocardiography (ICE) may make this percutaneous procedure feasible in patients in whom transesophageal echocardiography (TEE) is inadvisable. Our aim was to assess the efficacy and safety of LAA closure and the feasibility of ICE compared to TEE to guide the procedure. In this cohort study of ...
Tópico(s): Cardiac tumors and thrombi
2018 - Elsevier BV | Revista Portuguesa de Cardiologia (English Edition)
Luís Amaro, Daniela M. Correia, Teresa Marques‐Almeida, Pedro M. Martins, Leyre Pérez‐Álvarez, José Luis Vilas‐Vilela, Gabriela Botelho, S. Lanceros‐Méndez, Clarisse Ribeiro,
Polymer-based piezoelectric biomaterials have already proven their relevance for tissue engineering applications. Furthermore, the morphology of the scaffolds plays also an important role in cell proliferation and differentiation. The present work reports on poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV), a biocompatible, biodegradable, and piezoelectric biopolymer that has been processed in different morphologies, including films, fibers, microspheres, and 3D scaffolds. The corresponding magnetically ...
Tópico(s): biodegradable polymer synthesis and properties
2018 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Mohamed M. A. Soliman, Maximilian N. Kopylovich, Elisabete C. B. A. Alegria, Ana P. C. Ribeiro, Ana M. Ferraria, A.M. Botelho do Rego, Luís M. Correia, Marta S. Saraiva, Armando J. L. Pombeiro,
Iron-containing particulate catalysts of 0.1–1 µm size were prepared by wet and ball-milling procedures from common salts and characterized by FTIR, TGA, UV-Vis, PXRD, FEG-SEM, and XPS analyses. It was found that when the wet method was used, semi-spherical magnetic nanoparticles were formed, whereas the mechanochemical method resulted in the formation of nonmagnetic microscale needles and rectangles. Catalytic activity of the prepared materials in the oxidation of 1-phenylethanol to acetophenone ...
Tópico(s): Catalysis and Oxidation Reactions
2020 - Multidisciplinary Digital Publishing Institute | Molecules

Taise Vieira Barros, Luís Freitas, José Maria Barbosa‐Filho, Xirley Pereira Nunes, Ana María Giulietti, Glória EP de Souza, Ricardo Ribeiro dos Santos, Milena Botelho Pereira Soares, Cristiane Flora Villarreal,
Abstract Objectives In the present study we investigated the antinociceptive, anti-inflammatory and antipyretic effects of 7-hydroxycoumarin (7-HC) in animal models. Methods The effects of oral 7-HC were tested against acetic acid-induced writhing, formalin test, tail flick test, complete Freund's adjuvant (CFA)-induced hypernociception, carrageenan-induced paw oedema, lipopolysaccharide-induced fever and the rota rod test. Key findings 7-HC (3–60 mg/kg) produced a dose-related antinociception against ...
Tópico(s): Essential Oils and Antimicrobial Activity
2010 - Oxford University Press | Journal of Pharmacy and Pharmacology
José Maria Cardoso, Ana Clara Ribeiro, João Botelho, Luís Proença, Susana Noronha, Ricardo Alves,
The aim of this study was to evaluate the possible relationships between polymorphisms in the interleukin-1 (IL-1) A, IL-1B, and IL-1RN genes and concentrations of the inflammatory mediators IL-1β, tumor necrosis factor-alpha (TNF-α), and prostaglandin E2 (PGE2) in peri-implant crevicular fluid (PICF). A cross-sectional analytical study was conducted on 51 patients with dental implants. Samples from the buccal mucosa were obtained, and genetic analysis was performed using the real-time polymerase chain ...
Tópico(s): Dental Radiography and Imaging
2024 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences

Gabriela da Silva Cruz, Ana Luiza Dias Ângelo, Ticiana Ferreira Larocca, Carolina Thé Macêdo, Márcia Noya-Rabelo, Luís Cláudio Lemos Correia, Jorge Andion Torreão, Bruno Solano de Freitas Souza, Ricardo Ribeiro dos Santos, Milena Botelho Pereira Soares,
Background: Galectin-3, a β-galactoside binding lectin, has been described as a mediator of cardiac fibrosis in experimental studies and as a risk factor associated with cardiovascular events in subjects with heart failure.Previous studies have evaluated the genetic susceptibility to Chagas disease in humans, including the polymorphisms of cytokine genes, demonstrating correlations between the genetic polymorphism and cardiomyopathy development in the chronic phase.However, the relationship between ...
Tópico(s): Protein Tyrosine Phosphatases
2015 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Bruno Ribeiro, Luís Rogério de Oliveira Hein, Michelle Leali Costa, Petra Pötschke, T. Burkhart, Edson Cocchieri Botelho,
The aim of this work is obtain multiwalled carbon nanotube reinforced poly(phenylene sulfide) (PPS) nanostructured composites by melt mixing technique and further characterization of their morphological and thermal properties. Transmission electronic microscopy and scanning electron microscopy analysis were performed to evaluate the quality of multi-walled carbon nanotubes (MWCNT) dispersion throughout the PPS matrix. The incorporation of nanofiller in polymeric matrix was responsible for an increase ...
Tópico(s): Polymer crystallization and properties
2015 - Wiley | Polymer Composites

Sílvio Cunha, José Cláudio Serafim, Lourenço Luís Botelho de Santana, Fabiano Damasceno, José Tiago Menezes Correia, Airam Oliveira Santos, Mona N. Oliveira, Janaína da Silva Ribeiro, Jéssika Alves Oliveira Amparo, Sílvia Lima Costa,
Multifunctionalized 2‐pyrrolinones were synthesized from the formal aza‐[3 + 2] cycloaddition reaction of acyclic enaminones and diphenylcyclopropenone. For primary enaminones, solventless reaction under microwave heating was developed. On the other hand, catalysis by Bi 2 O 3 under conventional heating was the more suitable strategy when secondary enaminones were employed. These conditions allowed the synthesis of a set of 2‐pyrrolinones with two vicinal phenyl substituents, which were evaluated ...
Tópico(s): Catalytic C–H Functionalization Methods
2017 - Wiley | Journal of Heterocyclic Chemistry

Carolina Thé Macêdo, Ticiana Ferreira Larocca, Márcia Noya-Rabelo, Luís Cláudio Lemos Correia, Moisés Imbassahy Guimarães Moreira, Alessandra Carvalho Caldas, Jorge Andion Torreão, Bruno Solano de Freitas Souza, Ricardo Ribeiro dos Santos, Milena Botelho Pereira Soares,
One of the most challenging issues of chronic Chagas disease is to provide earlier detection of heart involvement. Two-dimensional speckle tracking (2-D ST) echocardiography, a new imaging modality with useful applications in several cardiac diseases, has been validated for subjects with myocardial infarction against cardiac magnetic resonance (CMR). Here we hypothesize that the longitudinal global strain (LGS) has an incremental value to ejection fraction for predicting myocardial fibrosis in subjects ...
Tópico(s): Cardiac Imaging and Diagnostics
2015 - Elsevier BV | IJC Heart & Vasculature

Caroline Sousa Ribeiro Adeodato, Gutemberg Gomes Alves, Ana Maria Nunes Botelho, Isleine Portal Caldas, Fabiano Palmeira Gonçalves, Luís Felipe Ribeiro Pinto, Sheila Coelho Soares-Lima, Marina Chianello Nicolau Fagundes, Daniele Masterson, Pantaleo Scelza, Míriam Zaccaro Scelza,
Tópico(s): NF-κB Signaling Pathways
2020 - Elsevier BV | Archives of Oral Biology

Enéas Galdini Ferrazoli, Miriam Marcela Blanco, Simone Bittencourt, André Luís Lacerda Bachi, Luciana Bahia, Milena Botelho Pereira Soares, Ricardo Ribeiro‐dos‐Santos, Luiz E. Mello, Beatriz M. Longo,
Abstract Background Bone marrow is an accessible source of progenitor cells, which have been investigated as treatment for neurological diseases in a number of clinical trials. Here we evaluated the potential benefit of bone marrow cells in protecting against convulsive seizures induced by maximum electroconvulsive shock (MES), a widely used model for screening of anti-epileptic drugs. Behavioral and inflammatory responses were measured after MES induction in order to verify the effects promoted ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2013 - BioMed Central | BMC Neuroscience

Marília Teresa de Oliveira, Raqueli Teresinha França, João Pedro Scussel Feranti, A.S. Coutinho Júnior, André Vasconcelos Soares, Felipe Ribeiro Botelho Santos, Luís Felipe Dutra Corrêa, Hellen Fialho Hartmann, Saulo Tadeu Lemos Pinto Filho, Rafael Oliveira Chaves, V Pohl, Maurício Veloso Brun,
O objetivo deste estudo foi avaliar a eficácia do meloxicam associado ou não ao tramadol, no controle da dor após ovário-histerectomia (OVH) laparoscópica com dois portais. Foram selecionadas 14 cadelas hígidas. Os animais foram separados de forma aleatória, em dois grupos. O grupo M (GM) recebeu meloxicam (0,2mg kg-1, s.i.d.), enquanto os animais do grupo MT (GMT) receberam a associação de meloxicam (0,2mg kg-1, s.i.d.) e tramadol (4mg kg-1, t.i.d.), ambos durante dois dias de pós-operatório. Para avaliação ...
Tópico(s): Veterinary Equine Medical Research
2016 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Arquivo Brasileiro de Medicina Veterinária e Zootecnia

Vivian de Oliveira, André Luís Aroni, Luciana Botelho Ribeiro, Kauan Galvão Morão, Afonso Antônio Machado,
O Instagram é um aplicativo de rede social que possibilita ao usuário editar as fotos realizadas por meio de dispositivos móveis e compartilhá-las com o mundo, sendo hoje a segunda maior rede social em número de usuários. Diante desse fenômeno, o objetivo do estudo foi verificar o conteúdo das fotos postadas no Instagram por atletas olímpicos brasileiros. Foram analisadas por um período de quatro meses as fotos postadas pelos atletas que foram medalhistas nos Jogos Olímpicos de Londres, baseando- ...
Tópico(s): Cultural, Media, and Literary Studies
2018 - Programa de Pós Graduação em Comunicação | Animus Revista Interamericana de Comunicação Midiática