Pedro Pimentel‐Nunes, Luís Pedro Afonso, Paula Lopes, Roberto Roncon‐Albuquerque, Nádia Gonçalves, Rui Henrique, Luís Moreira‐Dias, Adelino Leite‐Moreira, Mário Dinis‐Ribeiro,
TLRs are important innate immunity receptors. Even though TLR2, 4 and 5 appear to be important for Helicobacter pylori (HP) recognition, their role in the evolution of gastritis to more advanced lesions is still unknown. To compare the expression of TLR2, 4 and 5 in normal gastric mucosa, HP+ gastritis, intestinal metaplasia, dysplasia and adenocarcinoma. Immunohistochemistry for TLR2, 4 and 5 was performed with anti-TLR2-TLR4-TLR5 antibodies in 117 histological samples of normal gastric mucosa (n = ...
Tópico(s): Immune Response and Inflammation
2011 - Springer Science+Business Media | Pathology & Oncology Research
Pedro Pimentel‐Nunes, Mário Dinis‐Ribeiro, João–Bruno Soares, Ricardo Marcos‐Pinto, Cristina Santos, Carla Rolanda, Ronaldo Rocha Bastos, Miguel Areia, LP Afonso, Jacques Bergman, Prateek Sharma, Takuji Gotoda, Rui Henrique, Luís Moreira‐Dias,
Background and study aim: The reliability and external validity of narrow band imaging (NBI) in the stomach have not been described consistently. The aim of the current study was to describe and estimate the accuracy and reliability of a simplified classification system for NBI in the diagnosis of gastric lesions. Methods: Consecutive patients undergoing NBI endoscopy at two reference centers (n = 85, 33 % with dysplasia) were included in two studies. In total, 224 different areas were biopsied and recorded onto ...
Tópico(s): Gastroesophageal reflux and treatments
2012 - Thieme Medical Publishers (Germany) | Endoscopy
Pedro Pimentel‐Nunes, Nádia Gonçalves, Inês Boal‐Carvalho, Luís Pedro Afonso, Paula Lopes, Roberto Roncon‐Albuquerque, Rui Henrique, Luís Moreira‐Dias, Adelino Leite‐Moreira, Mário Dinis‐Ribeiro,
Abstract Background Toll‐like receptors ( TLR ) are essential for H elicobacter pylori ( HP ) recognition. Their role in the progression of gastric lesions leading to cancer is not established. Aim To evaluate for the first time in humans the expression of TLR 2, TLR 4, and TLR 5, as well as the expression of other related molecules in the entire sequence of gastric lesions. Methods Biopsy samples (n = 80, 48% HP +) from normal mucosa, HP gastritis, metaplasia, dysplasia or adenocarcinoma were obtained from 44 ...
Tópico(s): Immune Response and Inflammation
2012 - Wiley | Helicobacter
Pedro Pimentel‐Nunes, Nádia Gonçalves, Inês Boal‐Carvalho, Luís Pedro Afonso, Paula Lopes, Roberto Roncon‐Albuquerque, João–Bruno Soares, Elisabete Cardoso, Rui Henrique, Luís Moreira‐Dias, Mário Dinis‐Ribeiro, Adelino Leite‐Moreira,
Background Animal data suggest that Toll-like receptors (TLR) may play an important role in colon carcinogenesis. Studies in humans to support that hypothesis are scarce. Aim To evaluate the expression of TLR2, TLR4 and TLR5, and the expression of several other related molecules, in different human colonic lesions. Methods Colon biopsy samples from normal mucosa, normal mucosa adjacent to lesion, adenoma or sporadic carcinoma were obtained from 35 consecutive patients undergoing colonoscopy. Quantification ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2012 - BMJ | Journal of Clinical Pathology
João–Bruno Soares, Pedro Pimentel‐Nunes, Luís Pedro Afonso, Carla Rolanda, Paula Lopes, Roberto Roncon‐Albuquerque, Nádia Gonçalves, Inês Boal‐Carvalho, Fernando Pardal, Susana Lopes, Guilherme Macedo, Lúcio Lara Santos, Rui Henrique, Luís Moreira‐Dias, Raquel Gonçalves, Mário Dinis‐Ribeiro, Adelino Leite‐Moreira,
We evaluated expression of TLR2, TLR4 and proinflammatory genes [NF-κB, TNF-α, cyclooxygenase-2 (COX-2)] in liver samples of patients in different stages of liver disease. Fifteen patients with unexplained transaminases elevation (reference group), 22 with viral chronic hepatitis (hepatitis group), 14 with virus-induced severe fibrosis/cirrhosis (cirrhosis group) and 10 with hepatocarcinoma (hepatocarcinoma group) were consecutively included in the study. Quantification of TLR2, TLR4, NF-κB, TNF-α and ...
Tópico(s): Hepatitis B Virus Studies
2012 - SAGE Publishing | Innate Immunity
Produção Nacional
Revisado por pares
Destaca-se o período de 1830 a 1858/62 para o estudo das relações entre o comércio proibido de escravos no Brasil e a expansão do capitalismo mundial. Sem desprezar as particularidades brasileiras - como a condição escravagista e a baixa tecnologia -, ressaltam-se os aspectos do capitalismo dos países europeus e dos Estados Unidos, além da situação complexa do comércio de escravos para o Caribe. Conclui-se que o tráfico negreiro se manteve no Brasil depois de proibido porque ofereceu respostas ao capitalismo ...
Tópico(s): History of Colonial Brazil
1988 - Universidade de São Paulo. Instituto de Estudos Brasileiros | Revista do Instituto de Estudos Brasileiros
Produção Nacional
Revisado por pares
Bruno Henriques Dias, André Luís Marques Marcato, Reinaldo Castro Souza, Murilo Pereira Soares, Ivo Chaves da Silva, Edimar J. de Oliveira, Rafael Bruno S. Brandi, Tales Pulinho Ramos,
This paper presents a new approach for the expected cost‐to‐go functions modeling used in the stochastic dynamic programming (SDP) algorithm. The SDP technique is applied to the long‐term operation planning of electrical power systems. Using state space discretization, the Convex Hull algorithm is used for constructing a series of hyperplanes that composes a convex set. These planes represent a piecewise linear approximation for the expected cost‐to‐go functions. The mean operational costs for using ...
Tópico(s): Electric Power System Optimization
2010 - Hindawi Publishing Corporation | Mathematical Problems in Engineering
Produção Nacional
Revisado por pares
Isabela Miranda de Mendonça, Ivo Chaves da Silva, Bruno Henriques Dias, André Luís Marques Marcato,
This study presents a new strategy aimed at the search space reduction and initialization of the multimodal optimization process to solve the problem of static expansion planning of electric power transmission systems. To this end, the proposed methodology first uses a constructive heuristic algorithm based on a portfolio of indices, in which the expansion decisions are relaxed and represented through the hyperbolic tangent function. By considering different slopes of the hyperbolic tangent function, ...
Tópico(s): Smart Grid Energy Management
2016 - Elsevier BV | Electric Power Systems Research
Produção Nacional
Revisado por pares
Ana Márcia Viana Wanzeler, Francisco Montagner, Henrique Timm Vieira, Heraldo Luís Dias da Silveira, Nádia Assein Arús, Mariana Boessio Vizzotto,
This study evaluated the influence of cone-beam computed tomography (CBCT) on endodondists' level of confidence in their diagnosis of endodontic cases and their treatment plans.Twenty clinical cases with periapical radiographs and small-volume CBCT scans were classified according to the American Association of Endodontists guidelines. Information was provided on patient clinical history, and both extraoral and intraoral examinations were simulated. Fifteen endodontists filled out 2 questionnaires. ...
Tópico(s): Medical Malpractice and Liability Issues
2019 - Elsevier BV | Journal of Endodontics
Produção Nacional
Revisado por pares
Rafael Bruno S. Brandi, Tales Pulinho Ramos, Bruno Henriques Dias, André Luís Marques Marcato, Ivo Chaves da Silva,
This paper proposes an iterative process to select the cuts that model the cost-to-go functions of stochastic dynamic programming (SDP) and stochastic dual dynamic programming (SDDP) algorithms. This approach is applied to the medium/long-term operation planning of hydrothermal systems. The main idea of the proposed algorithm is to improve the performance of the SDP and SDDP methods applied to the problem by iteratively adding cuts to the linear programming instances. Also, some case studies considering ...
Tópico(s): Water Systems and Optimization
2015 - Elsevier BV | Electric Power Systems Research
This work examines the imprionement of slaves because of the 1798 revolutionary movement in the city of Salvador (Bahia). All of them were included in the investigation healded by the judge Francisco Alvares da Costa Pinto. Eleven slaves, one of whom died in prision. Among the condemned, three were exiled to the West Coast of Africa: José Félix, Luís de França Pires and Cosme Damião: two were banished from Bahia: Manuel José de Vera Cruz and Inácio Pires. Only one among those slaves was African-born: ...
Tópico(s): Colonialism, slavery, and trade
1992 - Universidade de São Paulo. Instituto de Estudos Brasileiros | Revista do Instituto de Estudos Brasileiros
Maria Gouveia, Carla Henriques, Luís C. Dias,
This paper assesses the relative eco-efficiency changes in the electricity and gas sector (E&G)' production and consumption chains in 28 European countries. We propose a novel robustness assessment for the productivity index, specifically adjusted to value-based data envelopment analysis. Overall, results indicate that total factor productivity gains have been mainly driven by the catch-up effect across all chains of the E&G sector. When a more demanding perspective concerning negative environmental ...
Tópico(s): Environmental Impact and Sustainability
2023 - Elsevier BV | Socio-Economic Planning Sciences
Produção Nacional
Maria Cícera dos Santos de Albuquerque, Dilma Ferreira Silva de Souza, Willams Henrique da Costa Maynart, Luís Filipe Dias Bezerra, Adnez Regina Tertuliano da Silva Cassimiro, Jairo Calado Cavalcante,
ABSTRACT Objective: to analyze the empathy of nursing professionals who work in an urgency and emergency hospital service. Method: a cross-sectional study with 230 nursing professionals working in a public hospital in Maceió (Alagoas/Brazil). Data collected by sociodemographic questionnaire and Empathy Inventory between 2014 and 2015. Descriptive statistics of the data, analysis of variance and Cronbach's alpha of significance 0.05. Results: out of the 230 professionals, 59 were nurses and 171 mid- ...
Tópico(s): Healthcare professionals’ stress and burnout
2019 - Universidade Federal de Santa Catarina, Programa de Pós Graduação em Enfermagem | Texto & Contexto - Enfermagem
Produção Nacional
Revisado por pares
Francisco Antunes Dias, Luís Henrique de Castro-Afonso, Maria Clara Zanon Zotin, Frederico Fernandes Alessio-Alves, Rui Martins, Millene Rodrigues Camilo, Guilherme Seizem Nakiri, Daniel Giansante Abud, Octávio Marques Pontes‐Neto,
<b><i>Background:</i></b> Basilar artery occlusion (BAO) is a rare stroke subtype with high mortality rates. Best BAO reperfusion strategy is still controversial. <b><i>Objective:</i></b> We aim to describe outcomes of BAO patients submitted to mechanical thrombectomy (MT) in a comprehensive stroke center in Brazil and analyze which previous published computed tomography angiography (CTA) collateral score better predict functional outcomes. <b><i> ...
Tópico(s): Peripheral Artery Disease Management
2019 - Karger Publishers | Cerebrovascular Diseases
Produção Nacional
Revisado por pares
José Raphael Olegário França, Gabriel K.P. Barrios, Henrique Dias Gatti Turrer, Luís Marcelo Tavares,
Tópico(s): Metal Extraction and Bioleaching
2020 - Elsevier BV | Minerals Engineering
Produção Nacional
Daniel Souza Dias, Luís Henrique M. K. Costa, Marcelo Dias de Amorim,
All means will be welcome to help data flow across smart cities. As a matter of fact, smart cities widely rely in sensing the environment, an action that is prone to generating huge amounts of data. A major challenge is how to collect such data in an efficient way without the need to deploy, whenever necessary, extra (costly) cellular infrastructure. In this paper, we examine the possibility of creating a delay-tolerant vehicular network in the city of Rio de Janeiro, Brazil, using the public transportation ...
Tópico(s): Opportunistic and Delay-Tolerant Networks
2018 - Elsevier BV | Vehicular Communications
Produção Nacional
Revisado por pares
Diego Henrique Mirandola Dias Vieira, Luís F. Rangel, Vinícius Panciera Tagliavini, Vanessa Doro Abdallah, Maria J. Santos, Rodney Kozlowiski de Azevedo,
Tópico(s): Parasite Biology and Host Interactions
2020 - Springer Science+Business Media | Parasitology Research
Produção Nacional
Revisado por pares
Fábio Luís Forti, Matheus Henrique Dias, Hugo A. Armelin,
Tópico(s): Regulation of Appetite and Obesity
2006 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Produção Nacional
Revisado por pares
Leandro Rodrigues de Lemos, Igor José Boggione Santos, Guilherme Dias Rodrigues, Gabriel Max Dias Ferreira, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva, Raquel Moreira Maduro de Carvalho,
The phase compositions in liquid−liquid equilibria of aqueous two-phase systems (ATPS) composed of the poly(ethylene oxide)− poly(propylene oxide)−poly(ethylene oxide) (PEO−PPO−PEO) triblock copolymer L35 and various salt solutions (sodium carbonate, sodium succinate, sodium acetate, ammonium citrate, and ammonium sulfate) at several temperatures, (283.15, 298.15, and 313.15) K, are presented. The influence of temperature in the binodal position was pronounced for almost all of the ATPS's, with the ...
Tópico(s): Process Optimization and Integration
2009 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
Guilherme Dias Rodrigues, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva,
The restricted availability of water sources suitable for consumption and high costs for obtaining potable water has caused an increase of the conscience concerning the use.Thus, there is a high demand for "environmentally safe methods" which are according to the principles of Green Chemistry.Moreover, these methods should be able to provide reliable results for the analysis of water quality for various pollutants, such as phenol.In this work, greener alternatives for sample preparation for phenol ...
Tópico(s): Analytical chemistry methods development
2010 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Leandro Rodrigues de Lemos, RAQUEL A. CAMPOS, Guilherme Dias Rodrigues, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva,
The separation of copper and zinc was studied using aqueous two-phase systems (ATPSs) formed by triblock copolymers (L64), electrolyte (MgSO4, Li2SO4 or Na2C4H4O6) and water in the presence of 1-(2-pyridylazo)-2-naphthol (PAN) as an extractor. The separation behavior of the metals is affected by the quantity of extractor added, the pH of the system, the nature of the ATPS electrolyte and the system composition. The maximum separation (SCu,Zn = 204) of Cu and Zn was obtained with the L64 + Na2C4H4O6 ATPS ...
Tópico(s): Ionic liquids properties and applications
2013 - Elsevier BV | Separation and Purification Technology
Produção Nacional
Revisado por pares
Carini Aparecida Lelis, Eliara Acipreste Hudson, Guilherme Max Dias Ferreira, Gabriel Max Dias Ferreira, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva, Maximiliano Soares Pinto, Ana Clarissa dos Santos Pires,
The interaction between Allura Red and bovine serum albumin (BSA) was studied in vitro at pH 7.4. The fluorescence quenching was classified as static quenching due to the formation of AR–BSA complex, with binding constant (K) ranging from 3.26 ± 0.09 to 8.08 ± 0.06 104 L.mol−1, at the warfarin binding site of BSA. This complex formation was driven by increasing entropy. Isothermal titration calorimetric measurements also showed an enthalpic contribution. The Allura Red diffusion coefficient determined ...
Tópico(s): Analytical Chemistry and Chromatography
2016 - Elsevier BV | Food Chemistry
Produção Nacional
Revisado por pares
Filipe Simões Teodoro, Stela Nhandeyara do Carmo Ramos, Megg Madonyk Cota Elias, Aparecida Barbosa Mageste, Gabriel Max Dias Ferreira, Luís Henrique Mendes da Silva, Laurent Frédéric Gil, Leandro Vinícius Alves Gurgel,
A new carboxylated cellulose derivative (CTA) was prepared from the esterification of cellulose with 1,2,4-Benzenetricarboxylic anhydride. CTA was characterized by percent weight gain (pwg), amount of carboxylic acid groups (nCOOH), elemental analysis, FTIR, TGA, solid-state (13)C NMR, X-ray diffraction (DRX), specific surface area, pore size distribution, SEM and EDX. The best CTA synthesis condition yielded a pwg and nCOOH of 94.5% and 6.81mmolg(-1), respectively. CTA was used as an adsorbent material ...
Tópico(s): Nanomaterials for catalytic reactions
2016 - Elsevier BV | Journal of Colloid and Interface Science
Produção Nacional
Jaqueline de Paula Rezende, Guilherme Max Dias Ferreira, Gabriel Max Dias Ferreira, Luís Henrique Mendes da Silva, Maria do Carmo Hepanhol da Silva, Maximiliano Soares Pinto, Ana Clarissa dos Santos Pires,
Bovine serum albumin (BSA) has been recognized as a marker of the cow's health, milk quality, an allergenic protein and as a carrier. Its detection is important in the food, pharmaceutical and medical industries. However, traditional techniques used to detect BSA are often time-consuming, expensive, and show limited sensitivity. This paper describes properties of polydiacetylene-triblock copolymer (L64) nanosensors, synthesized to easily detect BSA. Sensor efficiency was studied as a function of nanosensor ...
Tópico(s): Lipid Membrane Structure and Behavior
2016 - Elsevier BV | Materials Science and Engineering C
Produção Nacional
Revisado por pares
Amália Luísa Pedrosa Xavier, Oscar Fernando Herrera Adarme, Laís Milagres Furtado, Gabriel Max Dias Ferreira, Luís Henrique Mendes da Silva, Laurent Frédéric Gil, Leandro Vinícius Alves Gurgel,
In the second part of this series of studies, the monocomponent adsorption of Cu2+, Co2+ and Ni2+ onto STA adsorbent in a fixed-bed column was investigated and optimized using a 22 central composite design. The process variables studied were: initial metal ion concentration and spatial time, and the optimized responses were: adsorption capacity of the bed (Qmax), efficiency of the adsorption process (EAP), and effective use of the bed (H). The higher Qmax for Cu2+, Co2+ and Ni2+ were 1.060, 0.800 and ...
Tópico(s): Adsorption and biosorption for pollutant removal
2018 - Elsevier BV | Journal of Colloid and Interface Science
Produção Nacional
Revisado por pares
Leandro Rodrigues de Lemos, Igor José Boggione Santos, Guilherme Dias Rodrigues, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva,
We investigated the extraction behavior of Cu(II) in the aqueous two-phase system (ATPS) formed by (L35+MgSO(4)+H(2)O) or (L35+(NH(4))(2)SO(4)+H(2)O) in the presence of the extracting agent 1-(2-pyridylazo)-2-naphthol (PAN). At pH=3 and a PAN concentration of 0.285 mmol kg(-1), both ATPS lead to the effective separation of Cu(II) from other metallic ions (Zn(II), Co(II), Ni(II) and Fe(III)). High separation factors range between 1000 and 10,000 were obtained for the extraction of Cu(II) and concomitant ...
Tópico(s): Crystallization and Solubility Studies
2012 - Elsevier BV | Journal of Hazardous Materials
Produção Nacional
Revisado por pares
Silvia J. R. Vargas, Juan C. Quintão, Guilherme Max Dias Ferreira, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva,
In this work, an organic solvent-free extraction approach was developed to selectively separate La from Ce using an ionic liquid-based aqueous two-phase system (ILATPS). ILATPSs composed of 1-ethyl-3-methylimidazolium chloride, C2MIMCl, K2CO3 (or K2HPO4), and water at 283, 298, and 313 K were obtained. The biphasic region decreased slightly with increasing temperature. These ILATPSs were applied for the separation of lanthanum from cerium. Some parameters that affect the separation of La and Ce, such ...
Tópico(s): Ionic liquids properties and applications
2019 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
Rafael Bruno S. Brandi, André Luís Marques Marcato, Bruno Henriques Dias, Tales Pulinho Ramos, Ivo Chaves da Silva,
The long-term operation planning problem is generally solved by a chain of computational models based on Stochastic Dual Dynamic Programming (SDDP) considering a period of 5–10 years ahead. A recent issue that has arisen concerning this problem is to define a convergence criterion when using conditional value-at-risk (CVaR) with SDDP due to the lack of good upper bound estimators. The main contribution of this paper is to propose a convergence criterion in which including CVaR does not hinder convergence ...
Tópico(s): Electric Power System Optimization
2017 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Power Systems
Produção Nacional
Revisado por pares
Bruno Henriques Dias, Marcelo A. Tomim, André Luís Marques Marcato, Tales Pulinho Ramos, Rafael Bruno S. Brandi, Ivo Chaves da Silva, João Alberto Passos Filho,
In this paper, parallel processing techniques are employed to improve the performance of the stochastic dynamic programming applied to the long term operation planning of electrical power system. The hydroelectric plants are grouped into energy equivalent reservoirs and the expected cost functions are modeled by a piecewise linear approximation, by means of the Convex Hull algorithm. In order to validate the proposed methodology, data from the Brazilian electrical power system is utilized.
Tópico(s): Water Systems and Optimization
2013 - Elsevier BV | European Journal of Operational Research
Produção Nacional
Revisado por pares
Dayvid Rodrigues Couto, Talitha Mayumi Francisco, Mário Luís Garbin, Henrique Machado Dias, Miriam Cristina Alvarez Pereira, Luiz Menini Neto, José Eduardo Macedo Pezzopane,
Tópico(s): Plant Diversity and Evolution
2019 - Springer Science+Business Media | Plant Ecology