Itziar de Rojas, Sonia Moreno‐Grau, Niccolò Tesi, Benjamin Grenier‐Boley, Víctor Andrade, Iris E. Jansen, Nancy L. Pedersen, Najada Stringa, Anna Zettergren, Isabel Hernández, Laura Montrreal, Carmen Antúnez, Anna Antonell, Rick M. Tankard, Joshua C. Bis, Rebecca Sims, Céline Bellenguez, Inés Quintela, Antonio González-Pérez, Miguel Calero, Emilio Franco‐Macías, Juan Macı́as, Rafael Blesa, Laura Cervera‐Carles, Manuel Menéndez‐González, Ana Frank, José Luís Royo, Fermín Moreno, Raquel Huerto Vilas, Miquel Baquero, Mónica Díez-Fairén, Carmen Lage, Sebastián García‐Madrona, Pablo García‐González, Emilio Alarcón‐Martín, Sergi Valero, Óscar Sotolongo‐Grau, Abbe Ullgren, Adam C. Naj, Afina W. Lemstra, Alba Benaque, Alba Pérez‐Cordón, Alberto Benussi, Alberto Rábano, Alessandro Padovani, Alessio Squassina, Alexandre de Mendonça, Alfonso Arias Pastor, Almar A. L. Kok, Alun Meggy, Ana Belén Pastor, Ana Espinosa, Anaïs Corma‐Gómez, Ángel Martín Montes, Ángela Sanabria, Anita L. DeStefano, Anja Schneider, Annakaisa Haapasalo, Anne Kinhult Ståhlbom, Anne Tybjærg‐Hansen, Annette M. Hartmann, Annika Spottke, Arturo Corbatón Anchuelo, Arvid Rongve, Barbara Borroni, Beatrice Arosio, Benedetta Nacmias, Børge G. Nordestgaard, Brian W. Kunkle, Camille Charbonnier, Carla Abdelnour, Carlo Masullo, Carmen Martínez Rodríguez, Carmen Muñoz-Fernández, Carole Dufouil, Caroline Graff, Catarina B. Ferreira, Caterina Chillotti, Chandra A. Reynolds, Chiara Fenoglio, Christine Van Broeckhoven, Christopher Clark, Claudia Pisanu, Claudia L. Satizábal, Clive Holmes, Dolores Buiza‐Rueda, Dag Aarsland, Dan Rujescu, Daniel Alcolea, Daniela Galimberti, David Wallon, Davide Seripa, Edna Grünblatt, Efthimios Dardiotis, Emrah Düzel, Elio Scarpini, Elisa Conti, Elisa Rubino, Ellen Gelpí, Eloy Rodríguez‐Rodríguez, Emmanuelle Duron, Eric Boerwinkle, Evelyn Ferri, Fabrizio Tagliavini, Fahri Küçükali, Florence Pasquier, Florentino Sánchez-García, Francesca Mangialasche, Frank Jessen, Gaël Nicolas, Geir Selbæk, Gemma Ortega, Geneviève Chêne, Georgios M. Hadjigeorgiou, Giacomina Rossi, Gianfranco Spalletta, Giorgio Giaccone, Giulia Grande, Giuliano Binetti, Goran Papenberg, Harald Hampel, Henri Bailly, Henrik Zetterberg, Hilkka Soininen, Ida Karlsson, Ignacio Álvarez, Ildebrando Appollonio, Ina Giegling, Ingmar Skoog, Ingvild Saltvedt, Innocenzo Rainero, Irene Rosas Allende, Jakub Hort, Janine Diehl‐Schmid, Jasper Van Dongen, Jean‐Sébastien Vidal, Jenni Lehtisalo, Jens Wiltfang, Jesper Qvist Thomassen, Johannes Kornhuber, Jonathan L. Haines, Jonathan Vogelgsang, Juan A. Pineda, Juan Fortea, Julius Popp, Jürgen Deckert, Katharina Büerger, Kevin Morgan, Klaus Fließbach, Kristel Sleegers, Laura Molina‐Porcel, Lena Kilander, Leonie Weinhold, Lindsay A. Farrer, Li‐San Wang, Luca Kleineidam, Lucia Farotti, Lucilla Parnetti, Lucio Tremolizzo, Lucrezia Hausner, Luisa Benussi, Lutz Froelich, M. Arfan Ikram, M. Candida Deniz-Naranjo, Magda Tsolaki, Maiteé Rosende‐Roca, Malin Löwenmark, Marc Hulsman, Marco Spallazzi, Margaret A. Pericak‐Vance, Margaret M. Esiri, María Bernal Sánchez-Arjona, Carolina Dalmasso, Nicholas G. Martin, Marina Arcaro, Markus M. Nöthen, Marta Fernández‐Fuertes, Martin Dichgans, Martin Ingelsson, Martin J. Herrmann, Martin Scherer, Martin Vyhnálek, Mary H. Kosmidis, Mary Yannakoulia, Matthias Schmid, Michael Ewers, Michael T. Heneka, Michael Wagner, Michela Scamosci, Miia Kivipelto, Mikko Hiltunen, Miren Zulaica, Montserrat Alegret, Myriam Fornage, Natalia Roberto, Natasja M. van Schoor, Nazib M. Seidu, Nerisa Banaj, Nicola J. Armstrong, Nikolaos Scarmeas, Norbert Scherbaum, Oliver Goldhardt, Olivier Hanon, Oliver Peters, Olivia Anna Skrobot, Olivier Quenez, Ondřej Lerch, Paola Bossù, Paolo Caffarra, Paolo Rossi, Paraskevi Sakka, Patrizia Mecocci, Per Hoffmann, Peter Holmans, Peter Fischer, Peter Riederer, Qiong Yang, Iain Marshall, Raj N. Kalaria, Richard Mayeux, Rik Vandenberghe, Roberta Cecchetti, Roberta Ghidoni, Ruth Frikke‐Schmidt, Sandro Sorbi, Sara Hägg, Sebastiaan Engelborghs, Seppo Helisalmi, Sigrid Botne Sando, Silke Kern, Silvana Archetti, Silvia Boschi, Silvia Fostinelli, Silvia Gil, Silvia Mendoza, Simon Mead, Simona Ciccone, Srdjan Djurovic, Stefanie Heilmann-Heimbach, Steffi G. Riedel‐Heller, Teemu Kuulasmaa, Teodoro del Ser, Thibaud Lebouvier, Thomas Polak, Tiia Ngandu, Timo Grimmer, Valentina Bessi, Valentina Escott‐Price, Vilmantas Giedraitis, Vincent Deramecourt, Wolfgang Maier, Xueqiu Jian, Yolande A.L. Pijnenburg, A. David Smith, Aldo Saenz, Alessandra Bizzarro, Alessandra Lauria, Alessandro Vacca, Alina Solomon, Anna Anastasiou, Anna Richardson, Anne Boland, Anne Koivisto, Antonio Daniele, Antonio Greco, Arnaoutoglou Marianthi, Bernadette McGuinness, Bertrand Fin, Camilla Ferrari, Carlo Custodero, Carlo Ferrarese, Carlos Ingino, Carlos Mangone, Carlos Reyes Toso, Carmen Martínez, Carolina Cuesta, Carolina Muchnik, Catharine Joachim, Cecilia Ortiz, Céline Besse, Charlotte Johansson, C Zoia, Christoph Laske, Costas A. Anastasiou, Dana Lis Palacio, Daniel G. Politis, Martijn Huisman, David Craig, David M. Mann, David Neary, Deckert Jürgen, Delphine Daian, Diyana Belezhanska, Eduardo Kohler, Eduardo M. Castaño, Effrosyni Koutsouraki,
Genetic discoveries of Alzheimer's disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer's disease risk (near APP, CHRNE, PRKD3/NDUFAF7, ...
Nature Portfolio
Produção Nacional
Revisado por pares
Kamile Leonardi Dutra, Letícia Fernanda Haas, André Luís Porporatti, Carlos Flores‐Mir, Juliana Nascimento Santos, Luís André Mezzomo, Márcio Corrêa, Graziela De Luca Canto,
Endodontic diagnosis depends on accurate radiographic examination. Assessment of the location and extent of apical periodontitis (AP) can influence treatment planning and subsequent treatment outcomes. Therefore, this systematic review and meta-analysis assessed the diagnostic accuracy of conventional radiography and cone-beam computed tomographic (CBCT) imaging on the discrimination of AP from no lesion.Eight electronic databases with no language or time limitations were searched. Articles in which ...
Tópico(s): Drilling and Well Engineering
2016 - Elsevier BV | Journal of Endodontics
Produção Nacional
Revisado por pares
Fabiana T. Almeida, Camila Pachêco‐Pereira, André Luís Porporatti, Carlos Flores‐Mir, André Ferreira Leite, Graziela De Luca Canto, Eliete Neves Silva Guerra,
The oral manifestations of familial adenomatous polyposis (FAP) have been reported in the recent literature. Therefore, there has been growing interest in the characterization of the dento-osseous anomalies because they may precede colorectal cancer and may be used as a diagnostic marker. This systematic review and meta-analysis was performed to evaluate the published evidence for what are the oral manifestations of FAP and their frequency in affected individuals.The search was performed at Cochrane ...
Tópico(s): Colorectal Cancer Treatments and Studies
2015 - Wiley | Journal of Gastroenterology and Hepatology
Jiao Luo, Jesper Qvist Thomassen, Céline Bellenguez, Benjamin Grenier‐Boley, Itziar de Rojas, Atahualpa Castillo-Morales, Kayenat Parveen, Fahri Küçükali, Aude Nicolas, Oliver Peters, Anja Schneider, Martin Dichgans, Dan Rujescu, Norbert Scherbaum, Jürgen Deckert, Steffi G. Riedel‐Heller, Lucrezia Hausner, Laura Molina‐Porcel, Emrah Düzel, Timo Grimmer, Jens Wiltfang, Stefanie Heilmann‐Heimbach, Susanne Moebus, Thomas Tegos, Nikolaos Scarmeas, Jordi Clarimón, Fermín Moreno, Jordi Pérez‐Tur, María J. Bullido, Pau Pástor, Raquel Sánchez‐Valle, Victoria Álvarez, Merçé Boada, Pablo García‐González, Raquel Puerta, Pablo Mir, Luís Miguel Real, Gerard Piñol‐Ripoll, José María García‐Alberca, José Luís Royo, Eloy Rodríguez‐Rodríguez, Hilkka Soininen, Teemu Kuulasmaa, Alexandre de Mendonça, Shima Mehrabian, Jakub Hort, Martin Vyhnálek, Sven J. van der Lee, Caroline Graff, Goran Papenberg, Vilmantas Giedraitis, Anne Boland, Delphine Bacq‐Daian, Jean‐François Deleuze, Gaël Nicolas, Carole Dufouil, Florence Pasquier, Olivier Hanon, Stéphanie Debette, Edna Grünblatt, Julius Popp, Luisa Benussi, Daniela Galimberti, Beatrice Arosio, Patrizia Mecocci, Vincenzo Solfrizzi, Lucilla Parnetti, Alessio Squassina, Lucio Tremolizzo, Barbara Borroni, Benedetta Nacmias, Sandro Sorbi, Paolo Caffarra, Davide Seripa, Innocenzo Rainero, Antonio Daniele, Carlo Masullo, Gianfranco Spalletta, Julie Williams, Philippe Amouyel, Frank Jessen, Patrick G. Kehoe, Magda Tsolaki, Giacomina Rossi, Pascual Sánchez‐Juan, Kristel Sleegers, Martin Ingelsson, Ole A. Andreassen, Mikko Hiltunen, Cornelia M. van Duijn, Rebecca Sims, Wiesje M. van der Flier, Agustı́n Ruiz, Alfredo Ramı́rez, Jean‐Charles Lambert, Ruth Frikke‐Schmidt,
Importance An estimated 40% of dementia is potentially preventable by modifying 12 risk factors throughout the life course. However, robust evidence for most of these risk factors is lacking. Effective interventions should target risk factors in the causal pathway to dementia. Objective To comprehensively disentangle potentially causal aspects of modifiable risk factors for Alzheimer disease (AD) to inspire new drug targeting and improved prevention. Design, Setting, and Participants This genetic ...
Tópico(s): Folate and B Vitamins Research
2023 - American Medical Association | JAMA Network Open
Produção Nacional
Revisado por pares
Helena Polmann, Gilberto Melo, Jéssica Conti Réus, Fábio Luiz Domingos, Beatriz Dulcinéia Mendes de Souza, Ana Clara Loch Padilha, Thaís Mageste Duque, André Luís Porporatti, Carlos Flores‐Mir, Graziela De Luca Canto,
Abstract Background/Aim Combat sports might result in injuries to the face and teeth. However, it is unclear how often they occur and which sports presents the highest rates. The aim of this study was to investigate the prevalence of dentofacial injuries in combat sports participants. Material and Methods A systematic review was performed. Six main electronic databases and three grey literature databases were searched. Studies were blindly selected by two reviewers based on pre‐defined eligibility ...
Tópico(s): Injury Epidemiology and Prevention
2019 - Wiley | Dental Traumatology
Produção Nacional
Revisado por pares
Fernanda Weber Mello, Andressa Fernanda Paza Miguel, Dayane Machado Ribeiro, Bráulio Pasternak, André Luís Porporatti, Carlos Flores‐Mir, Ana Cristina Andrada, Lucas da Fonseca Roberti Garcia, Kamile Leonardi Dutra,
Tópico(s): Occupational health in dentistry
2019 - Springer Nature | Clinical Oral Investigations
Produção Nacional
Revisado por pares
Maria Carolina Ferreira, Isabela Porto de Toledo, Kamile Leonardi Dutra, Fabiane Miron Stefani, André Luís Porporatti, Carlos Flores‐Mir, Graziela De Luca Canto,
Summary Temporomandibular disorder ( TMD ) is an umbrella condition presenting several signs and symptoms including pain in the temporomandibular joint ( TMJ ) and masticatory muscles, articular noises, earache, headache, irregular or restricted jaw function, chewing difficulty, and limited mouth opening. Such TMD impairment may cause disorders during the chewing process. Therefore, the purpose of this systematic review was to assess chewing dysfunctions measured by sEMG , and their association with TMD . A ...
Tópico(s): Voice and Speech Disorders
2018 - Wiley | Journal of Oral Rehabilitation
Produção Nacional
Revisado por pares
Gilberto Melo, Elis Ângela Batistella, Eduardo Bertazzo-Silveira, Thaís Marques Simek Vega Gonçalves, Beatriz Dulcinéia Mendes de Souza, André Luís Porporatti, Carlos Flores‐Mir, Graziela De Luca Canto,
Statement of problem Ceramic restorations are popular because of their excellent optical properties. However, failures are still a major concern, and dentists are confronted with the following question: is sleep bruxism (SB) associated with an increased frequency of ceramic restoration failures? Purpose The purpose of this systematic review and meta-analysis was to assess whether the presence of SB is associated with increased ceramic restoration failure. Material and methods Observational studies ...
Tópico(s): Dental materials and restorations
2017 - Elsevier BV | Journal of Prosthetic Dentistry
Victòria Reyes-García, José Luís Molina, Laura Calvet-Mir, Laura Aceituno-Mata, Juan José de León Lastra, Ricardo Ontillera, Montse Parada, Manuel Pardo‐de‐Santayana, Montserrat Rigat, Joan Vallès, Teresa Garnatje,
Abstract Background The idea that knowledge flows through social networks is implicit in research on traditional knowledge, but researchers have paid scant attention to the role of social networks in shaping its distribution. We bridge those two bodies of research and investigate a) the structure of network of exchange of plant propagation material (germplasm) and b) the relation between a person’s centrality in such network and his/her agroecological knowledge. Methods We study 10 networks of germplasm ...
Tópico(s): Culinary Culture and Tourism
2013 - BioMed Central | Journal of Ethnobiology and Ethnomedicine
M.I. Martinez-Mir, Luís Estañ, Francisco J. Morales‐Olivas, E. Rubio,
1. The effect of histamine and histamine H1- and H2-receptor agonists on isolated myometrium strips of premenopausal women has been examined. The effect of acetylcholine was also determined. 2. Histamine, 2-pyridylethylamine, 4-methylhistamine and acetylcholine, but not dimaprit, produced a concentration-related contractile response in human isolated myometrial strips. Histamine also produced a further contraction in human isolated myometrial strips precontracted with KCl (55 mM). 3. The contractile ...
Tópico(s): Mast cells and histamine
1992 - Wiley | British Journal of Pharmacology
Inocencia Martínez‐Mir, Luís Estañ, Francisco J. Morales‐Olivas, E. Rubio,
We investigated the spontaneous uterine activity of isolated corpus uteri myometrial strips from 30 patients with nonpathologic myometrium, 26 patients with uterine myoma, 23 patients with uterine adenomyosis, and three patients with uterine malignancy. We also investigated the influence of these conditions on the response of the uterus to histamine. The results show the same qualitative cyclic changes of the spontaneous motility of isolated myometrial strips throughout the menstrual cycle in all ...
Tópico(s): Uterine Myomas and Treatments
1990 - Elsevier BV | American Journal of Obstetrics and Gynecology
María José Aguilar Cordero, Luís Estañ, Inocencia Martínez‐Mir, M Martínez-Abad, E. Rubio, Francisco J. Morales‐Olivas,
The aim of the present work is to investigate the effects of dopamine on isolated rat colon strips, and whether dopamine receptors are involved in these effects. Experiments on spontaneous motility and under potassium contraction were performed with dopamine and isoprenaline, both in the absence and presence of antagonists (distal colon strips, isotonic recording, Tyrode solution, 31 degrees C, 1 g of resting tension). At higher concentration (10(-4) mol/L), dopamine abolished spontaneous motility ...
Tópico(s): Neuropeptides and Animal Physiology
2005 - NRC Research Press | Canadian Journal of Physiology and Pharmacology
Hamidreza Khodadadi, Luís Azcona, Vajiheh Aghamollaii, Mir Davood Omrani, Masoud Garshasbi, Shaghayegh Taghavi, Abbas Tafakhori, Gholam Ali Shahidi, Javad Jamshidi, Hossein Darvish, Coro Paisán‐Ruiz,
Introduction Atypical parkinsonism is a neurodegenerative disease that includes diverse neurological and psychiatric manifestations. Objectives We aimed to identify the disease-cauisng mutations in a consanguineous family featuring intellectual disability and parkinsonism. Methods Full phenotypic characterization, followed by genome-wide single-nucleotide polymorphism genotyping and whole-genome sequencing, was carried out in all available family members. Results The chromosome, 2p23.3, was identified ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2016 - Wiley | Movement Disorders
Sonia Moreno‐Grau, Itziar de Rojas, Isabel Hernández, Inés Quintela, Laura Montrreal, Montserrat Alegret, Begoña Hernández‐Olasagarre, Laura Madrid, Antonio González‐Pérez, Olalla Maroñas, Maiteé Rosende‐Roca, Ana Mauleón, Liliana Vargas, Asunción Lafuente, Carla Abdelnour, Octavio Rodríguez‐Gómez, Silvia Gil, Miguel A. Santos‐Santos, Ana Espinosa, Gemma Ortega, Ángela Sanabria, Alba Pérez‐Cordón, Pilar Cañabate, Mariola Moreno, Sílvia Preckler, Susana Ruiz, Núria Aguilera, Juan A. Pineda, Juan Macı́as, Emilio Alarcón‐Martín, Óscar Sotolongo‐Grau, Carla Abdelnour, N. Aguilera, Emilio Alarcón‐Martín, Montserrat Alegret, Alba Benaque, Merçé Boada, Mar Buendía, Pilar Cañabate, Ãngel Carracedo, Arturo Corbatón Anchuelo, Itziar de Rojas, S. Diego, Ana Espinosa, A. Gailhajenet, Pablo García‐González, Silvia Gil, M. Guitart, Antonio González‐Pérez, Iván Hernández Ramírez, Marta Ibarria, A. Lafuente, Juan Macı́as, Olalla Maroñas, Eden R. Martin, María Teresa González Martínez, Marta Marquié, Ana Mauleón, Gemma C. Monté, Laura Montrreal, Sonia Moreno‐Grau, M. Moreno, Adelina Orellana, Gemma Ortega, A. Pancho, E. Pelejà, Alba Pérez‐Cordón, Juan A. Pineda, Sílvia Preckler, Inés Quintela, Luís Miguel Real, Octavio Rodríguez‐Gómez, Maiteé Rosende‐Roca, Agustı́n Ruiz, Susana Ruiz, María Eugenia Sáez, Ángela Sanabria, Miguel A. Santos‐Santos, Manuel Serrano‐Ríos, Óscar Sotolongo‐Grau, Lluís Tárraga, Sergi Valero, Liliana Vargas, Astrid Adarmes‐Gómez, Emilio Alarcón‐Martín, Ignacio Álvarez, Victoria Álvarez, G. Amer-Ferrer, M. Antequera, Carmen Antúnez, Miquel Baquero, M. Bernal, Rafael Blesa, Merçé Boada, Dolores Buiza‐Rueda, María J. Bullido, J A Burguera, Miguel Calero, F. Carrillo, Mario Carrión‐Claro, M. J. Casajeros, Jordi Clarimón, J. M. Cruz-Gamero, Marian M. de Pancorbo, Itziar de Rojas, Teodoro del Ser, Mónica Díez-Fairén, Juan Fortea, Emilio Franco, Ana Frank, José María García‐Alberca, S. García Madrona, Guillermo García‐Ribas, Pilar Gómez‐Garre, Israel Hernández, S. Hevilla, Silvia Jesús, Labrador Espinosa, Carmen Lage, Agustina Legaz, Alberto Lleó, Adolfo López de Munain, Sergio López‐García, Daniel Macías, Salvadora Manzanares, M. Marín, Juan Marín-Muñoz, Teresa J. Marin, Marta Marquié, Ángel Martín Montes, B. Martínez, Carmen Martı́nez, Verónica S. Martínez, Pablo Martínez-Lage Álvarez, Miguel Medina, Maite Mendióroz, Manuel Menéndez‐González, Pablo Mir, J.L. Molinuevo, Gemma C. Monté, Laura Montrreal, Sonia Moreno‐Grau, Adelina Orellana, Ana Belén Pastor, Pau Pástor, Jordi Pérez‐Tur, María Teresa Periñán, G. Piñol Ripoll, Alberto Rábano, Diego Real de Asúa, S. Rodrigo, Eloy Rodríguez‐Rodríguez, José Luís Royo, Agustı́n Ruiz, R. Sanchez del Valle Díaz, Pascual Sánchez‐Juan, Isabel Sastre, Óscar Sotolongo‐Grau, Luis Tárraga, Sergi Valero, M.P. Vicente, L. Vivancos, Marta Marquié, Gemma C. Monté, Sergi Valero, Alba Benaque, Jordi Clarimón, María J. Bullido, Guillermo García‐Ribas, Pau Pástor, Pascual Sánchez‐Juan, Victoria Álvarez, Gerard Piñol‐Ripoll, José María García‐Alberca, José Luís Royo, Emilio Franco, Pablo Mir, Miguel Calero, Miguel Medina, Alberto Rábano, Jesús Ávila, Carmen Antúnez, Luís Miguel Real, Adelina Orellana, Ãngel Carracedo, María Eugenia Sáez, Lluís Tárraga, Merçé Boada, Agustı́n Ruiz,
Large variability among Alzheimer's disease (AD) cases might impact genetic discoveries and complicate dissection of underlying biological pathways.Genome Research at Fundacio ACE (GR@ACE) is a genome-wide study of dementia and its clinical endophenotypes, defined based on AD's clinical certainty and vascular burden. We assessed the impact of known AD loci across endophenotypes to generate loci categories. We incorporated gene coexpression data and conducted pathway analysis per category. Finally, ...
Tópico(s): Bioinformatics and Genomic Networks
2019 - Wiley | Alzheimer s & Dementia
Produção Nacional
Revisado por pares
Gilberto Melo, E. Casett, Juliana Stuginski‐Barbosa, Eliete Neves Silva Guerra, Daniel Araujo Fernandes, André Luís Porporatti, Carlos Flores‐Mir, Graziela De Luca Canto,
Summary The purpose of this study was to systematically review the literature for studies that assessed the effects of glucosamine supplements ( GS ) on pain and maximum mouth opening ( MMO ) restriction compared to other therapies, placebo or no intervention on painful temporomandibular joint osteoarthritis ( TMJ OA ). Randomised controlled trials were selected in a two‐phase process. Seven electronic databases, in addition to three grey literature databases, were searched. Risk of bias was assessed using the ...
Tópico(s): Pain Mechanisms and Treatments
2018 - Wiley | Journal of Oral Rehabilitation
Sonia Moreno‐Grau, María Victoria Fernández, Itziar de Rojas, Pablo García‐González, Isabel Hernández, Fabiana Farias, John Budde, Inés Quintela, Laura Madrid, Antonio González‐Pérez, Laura Montrreal, Emilio Alarcón‐Martín, Montserrat Alegret, Olalla Maroñas, Juan A. Pineda, Juan Macı́as, Carla Abdelnour, N. Aguilera, Emilio Alarcón‐Martín, Montserrat Alegret, Alba Benaque, Merçé Boada, Mar Buendía, Pilar Cañabate, Ãngel Carracedo, Arturo Corbatón Anchuelo, Itziar de Rojas, S. Diego, Ana Espinosa, A. Gailhajenet, Pablo García‐González, Saulo Gil, M. Guitart, Antonio González‐Pérez, Isabel Hernández, Marta Ibarria, A. Lafuente, Juan Macı́as, Olalla Maroñas, Eden R. Martin, María Teresa González Martínez, Marta Marquié, Ana Mauleón, Gemma C. Monté, Laura Montrreal, Sonia Moreno‐Grau, M. Moreno, Adelina Orellana, Gemma Ortega, A. Pancho, E. Pelejà, Alba Pérez‐Cordón, Juan A. Pineda, Sílvia Preckler, Inés Quintela, Luís Miguel Real, Octavio Rodríguez‐Gómez, Maiteé Rosende‐Roca, Agustı́n Ruiz, Susana Ruiz, María Eugenia Sáez, Ángela Sanabria, Miguel A. Santos‐Santos, Manuel Serrano‐Ríos, Óscar Sotolongo‐Grau, Lluís Tárraga, Sergi Valero, Liliana Vargas, Astrid Adarmes‐Gómez, Emilio Alarcón‐Martín, Ignacio Álvarez, Victoria Álvarez, G. Amer-Ferrer, M. Antequera, Carmen Antúnez, Miquel Baquero, M. Bernal, Rafael Blesa, Merçé Boada, Dolores Buiza‐Rueda, María J. Bullido, J A Burguera, Miguel Calero, F. Carrillo, Mario Carrión‐Claro, M. J. Casajeros, Jordi Clarimón, J. M. Cruz-Gamero, Marian M. de Pancorbo, Itziar de Rojas, Teodoro del Ser, Mónica Díez-Fairén, Juan Fortea, Emilio Franco, Ana Frank, José María García‐Alberca, S. García Madrona, Guillermo García‐Ribas, Pilar Gómez‐Garre, Isabel Hernández, S. Hevilla, Silvia Jesús, M. A. Labrador Espinosa, Carmen Lage, Agustina Legaz, Alberto Lleó, Adolfo López de Munain, Sara López‐García, Diego Macías Saint-Gerons, Salvadora Manzanares, M. Marín, Juan Marín-Muñoz, Teresa J. Marin, Marta Marquié, A. Martín-Montes, B. Martínez, Carmen Martı́nez, Verónica S. Martínez, Pablo Martínez-Lage Álvarez, Miguel Medina, Maite Mendióroz, Manuel Menéndez‐González, Pablo Mir, José Luís Molinuevo, Laura Montrreal, Sonia Moreno‐Grau, Adelina Orellana, Ana Belén Pastor, Pau Pástor, Jordi Pérez‐Tur, María Teresa Periñán, Gerard Piñol‐Ripoll, Alberto Rábano, Diego Real de Asúa, S. Rodrigo, Eloy Rodríguez‐Rodríguez, José Luís Royo, Agustı́n Ruiz, R. Sanchez del Valle Díaz, Pascual Sánchez‐Juan, I. Sastre, Óscar Sotolongo‐Grau, Lluís Tárraga, Sergi Valero, Mário Vicente, L. Vivancos, Marta Marquié, Sergi Valero, Alba Benaque, Jordi Clarimón, María J. Bullido, Guillermo García‐Ribas, Pau Pástor, Pascual Sánchez‐Juan, Victoria Álvarez, Gerard Piñol‐Ripoll, José María García‐Alberca, José Luís Royo, Emilio Franco‐Macías, Pablo Mir, Miguel Calero, Miguel Medina, Alberto Rábano, Jesús Ávila, Carmen Antúnez, Luís Miguel Real, Adelina Orellana, Ãngel Carracedo, María Eugenia Sáez, Lluís Tárraga, Merçé Boada, Carlos Cruchaga, Agustı́n Ruiz,
Abstract Long runs of homozygosity (ROH) are contiguous stretches of homozygous genotypes, which are a footprint of inbreeding and recessive inheritance. The presence of recessive loci is suggested for Alzheimer’s disease (AD); however, their search has been poorly assessed to date. To investigate homozygosity in AD, here we performed a fine-scale ROH analysis using 10 independent cohorts of European ancestry (11,919 AD cases and 9181 controls.) We detected an increase of homozygosity in AD cases compared ...
Tópico(s): Bioinformatics and Genomic Networks
2021 - Springer Nature | Translational Psychiatry
Shaghayegh Taghavi, Rita Chaouni, Abbas Tafakhori, Luís Azcona, Saghar Ghasemi Firouzabadi, Mir Davood Omrani, Javad Jamshidi, Babak Emamalizadeh, Gholam Ali Shahidi, Mona Ahmadi, Seyed Amir Hassan Habibi, Azadeh Ahmadifard, Atena Fazeli, Marzieh Motallebi, Peyman Petramfar, Saeed Askarpour, Shiva Askarpour, Hossein Ali Shahmohammadibeni, Neda Shahmohammadibeni, Hajar Eftekhari, Amir Ehtesham Shafiei Zarneh, Saeed Mohammadihosseinabad, Mehdi Khorrami, Safa Najmi, Ahmad Chitsaz, Parasto Shokraeian, Hossein Ehsanbakhsh, Jalal Rezaeidian, Reza Ebrahimi Rad, Faranak Madadi, Monavvar Andarva, Elham Alehabib, Minoo Atakhorrami, Seyed Erfan Mortazavi, Zahra Azimzadeh, Mahdis Bayat, Amir Mohammad Besharati, Mohammad Ali Harati-Ghavi, Samareh Omidvari, Zahra Dehghani-Tafti, Faraz Mohammadi, Banafsheh Mohammad Hossein Pour, Hamid Noorollahi Moghaddam, Ehsan Esmaili Shandiz, Arman Habibi, Zahra Taherian‐Esfahani, Hossein Darvish, Coro Paisán‐Ruiz,
In this study, the role of known Parkinson’s disease (PD) genes was examined in families with autosomal recessive (AR) parkinsonism to assist with the differential diagnosis of PD. Some families without mutations in known genes were also subject to whole genome sequencing with the objective to identify novel parkinsonism-related genes. Families were selected from 4000 clinical files of patients with PD or parkinsonism. AR inheritance pattern, consanguinity, and a minimum of two affected individuals ...
Tópico(s): Nuclear Receptors and Signaling
2017 - Springer Science+Business Media | Molecular Neurobiology
Laura Calvet-Mir, Maria Calvet-Mir, José Luís Molina, Victòria Reyes-García,
Calvet-Mir, L., M. Calvet-Mir, J. Luis Molina, and V. Reyes-García. 2012. Seed exchange as an agrobiodiversity conservation mechanism. A case study in Vall Fosca, Catalan Pyrenees, Iberian Peninsula. Ecology and Society 17(1): 29. https://doi.org/10.5751/ES-04682-170129
Tópico(s): Agriculture, Land Use, Rural Development
2012 - Resilience Alliance | Ecology and Society
Luís Máiz, Rafael Cantón, Nuria Mir, Fernando Baquero, Héctor Escobar,
Tópico(s): Bacterial biofilms and quorum sensing
1998 - Wiley | Pediatric Pulmonology
Luís Máiz, Rafael Cantón, Nuria Mir, Fernando Baquero, Héctor Escobar,
Tópico(s): Bacterial biofilms and quorum sensing
1998 - Wiley | Pediatric Pulmonology
Eduardo Bertazzo-Silveira, Cristian Maikel Kruger, Isabela Porto de Toledo, André Luís Porporatti, Bruce Dick, Carlos Flores‐Mir, Graziela De Luca Canto,
Abstract Background The aim of this systematic review was to answer the focused question, "In adults, is there any association between sleep bruxism (SB) and alcohol, caffeine, tobacco, or drug abuse?" Types of Studies Reviewed This systematic review included studies in which the investigators assessed SB diagnosis by using questionnaires, clinical assessment, or polysomnography and evaluated its association with alcohol, caffeine, tobacco, or drug abuse. The authors graded SB as possible, probable, or definitive. ...
Tópico(s): Obstructive Sleep Apnea Research
2016 - Elsevier BV | The Journal of the American Dental Association
Produção Nacional
Revisado por pares
Helena Polmann, Fábio Luiz Domingos, Gilberto Melo, Juliana Stuginski‐Barbosa, Eliete Neves Silva Guerra, André Luís Porporatti, Bruce Dick, Carlos Flores‐Mir, Graziela De Luca Canto,
Summary Background The purpose of this systematic review was to evaluate the association between sleep bruxism (SB) and anxiety symptoms in adults. Methods A systematic review was performed and studies assessing SB by means of questionnaires, clinical examination and/or polysomnography (PSG), and validated questionnaires to assess anxiety, were included. Search strategies were developed for seven main electronic databases. Risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal ...
Tópico(s): Voice and Speech Disorders
2019 - Wiley | Journal of Oral Rehabilitation
Produção Nacional
Revisado por pares
Gilberto Melo, Kamile Leonardi Dutra, Rubens Rodrigues Filho, Adriana Ortega, André Luís Porporatti, Bruce Dick, Carlos Flores‐Mir, Graziela De Luca Canto,
The purpose of this study was to systematically review the literature for studies that investigated the association between use of psychotropic medications and presence of sleep bruxism (SB). Observational studies were selected in a two-phase process. Searches were performed on six electronic databases, and a grey literature search was conducted on three databases. SB diagnosis was based on questionnaires or clinical examinations; no polysomnography examinations were performed. Risk of bias was assessed ...
Tópico(s): Sleep and Wakefulness Research
2018 - Wiley | Journal of Oral Rehabilitation
Produção Nacional
Revisado por pares
Eduardo Bertazzo-Silveira, Juliana Stuginski‐Barbosa, André Luís Porporatti, Bruce Dick, Carlos Flores‐Mir, Daniele Manfredini, Graziela De Luca Canto,
Tópico(s): Laser Applications in Dentistry and Medicine
2017 - Springer Nature | Clinical Oral Investigations
Victòria Reyes-García, José Luís Molina, James Broesch, Laura Calvet-Mir, Tomás Huanca, Judith Saus, Susan Tanner, William R. Leonard, Thomas W. McDade,
Tópico(s): Evolutionary Psychology and Human Behavior
2008 - Elsevier BV | Evolution and Human Behavior
Kai Fang, Ivy Ka Man Law, David Padua, Aristea Sideri, Vanessa Huang, Christopher G. Kevil, Dimitrios Iliopoulos, Charalabos Pothoulakis,
... M.M. Tu H.F. Liu C.J. Lui M.T. Lin S.C. Passenger strand miRNA miR-31* regulates the phenotypes of oral cancer cells ...
Tópico(s): Inflammation biomarkers and pathways
2017 - Elsevier BV | American Journal Of Pathology
Luís Estañ, Inocencia Martínez‐Mir, E. Rubio, Francisco J. Morales‐Olivas,
Tópico(s): Neuroendocrine regulation and behavior
1988 - Springer Science+Business Media | Naunyn-Schmiedeberg s Archives of Pharmacology
Produção Nacional
Revisado por pares
Mateus Cardoso Pereira, Fernanda Weber Mello, Dayane Machado Ribeiro, André Luís Porporatti, Sylvio da Costa, Carlos Flores‐Mir, Silvia Gianoni‐Capenakas, Kamile Leonardi Dutra,
To answer the focused question, "What are the prevalence of percutaneous injuries (PIs) on dentists, the location with the highest prevalence, and the dental instrument most responsible for these injuries?" As secondary outcomes, the prevalence by geographic location, type of PI, sex distribution, and dentist's specialty were also considered.Observational descriptive studies investigating the prevalence of percutaneous injuries on dentists were included.Five electronic databases and three partial ...
Tópico(s): Medical Malpractice and Liability Issues
2018 - Elsevier BV | Journal of Dentistry
Fei Chen, Angela M. Lui, Heidi Andrade, Christopher Valle, Hirah Mir,
The purpose of this study was to examine the effect of criteria-referenced formative assessment on achievement in the arts. Seventy-five schools in New York City were assigned to either the treatment or control condition. The treatment involved 3195 elementary, middle, or high school students instructed by 43 music, visual arts, theater, or dance teachers. The teachers were involved in a professional development program focused on formative assessment practices, particularly criteria-referenced ...
Tópico(s): Reflective Practices in Education
2017 - Springer Science+Business Media | Educational Assessment Evaluation and Accountability
Rosa Herrera, Jose De Andrés, Luís Estañ, Francisco J. Olivas, Inocencia Martínez‐Mir, Thorsten Steinfeldt,
The altered hemodynamics, and therefore the arterial hypotension is the most prevalent adverse effect after subarachnoid anesthesia. The objective of the study was to determine the exact role of local anesthetic selection underlying spinal anesthesia-induced hypotension in the elderly patient. We conducted a descriptive, observational pilot study to assess the hemodynamic impact of subarachnoid anesthesia with isobaric levobupivacaine versus hyperbaric bupivacaine for hip fracture surgery. Hundred ...
Tópico(s): Hemodynamic Monitoring and Therapy
2014 - BioMed Central | BMC Anesthesiology