Limpar
29 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ana Paula Tavares Magalhães,

... sua hostilidade concorreu para a queda do imperador Luís da Baviera. Pretende-se, nesse trabalho, avaliar as relações do ...

Tópico(s): Historical Education and Society

2008 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | História (São Paulo)

Artigo Brasil Produção Nacional Revisado por pares

Rafael Masot, Miguel Alcañíz, Ana Fuentes, Franciny Campos Schmidt, José Manuel Barat Baviera, Luís Gil, Diana Baigts, Ramón Martínez‐Máñez, Juán Soto,

The measurement of salt content in processed products still remains a problem to solve in the food industry due to the destructive nature of the conventional measurement methods. In this paper a method to assess salt content in food products such as cured ham or pork loin using impedance spectroscopy is presented. A low-cost system to carry out a punctual measurement of the impedance inside the food sample based on a non-destructive sensor was developed. The system includes an electronic equipment ...

Tópico(s): Meat and Animal Product Quality

2010 - Elsevier BV | Sensors and Actuators A Physical

Artigo Revisado por pares

Roberto H. Labrador, Rafael Masot, Miguel Alcañíz, Diana Baigts, Juán Soto, Ramón Martínez‐Máñez, Eduardo Garcı́a-Breijo, Luís Gil, José Manuel Barat Baviera,

A method for predicting levels of sodium chloride, sodium nitrite and potassium nitrate in minced meat by using a combination of two different electrochemical methods; namely an electronic tongue (ET) based on pulse voltammetry and electrochemical impedance spectroscopy measurements is proposed here. The measurements with the voltammetric ET were carried out on both saline solutions (brines) and minced meat, whereas the impedimetric sensor was used only in minced meat. The addition of the salts was ...

Tópico(s): Spectroscopy and Chemometric Analyses

2010 - Elsevier BV | Food Chemistry

Artigo Acesso aberto Revisado por pares

Eduardo Garcı́a-Breijo, José Manuel Barat Baviera, Olga L. Torres, Raúl Grau, Luís Gil, Javier Ibáñez, Miguel Alcañíz, Rafael Masot, Rubén Fraile,

Conductivity measurements of food systems are of high interest because they are related with food characteristics such as free water and salt content. Nevertheless, as far as now no devices have been developed for punctual conductivity measurements inside solid foods. The aim of this work was to develop a conductimeter which allows obtaining punctual measurements in different locations of solid foods. The sensor consists of a coaxial needle while an electrical sign controlled by microcontroller ...

Tópico(s): Meat and Animal Product Quality

2008 - Elsevier BV | Sensors and Actuators A Physical

Artigo Acesso aberto Revisado por pares

Luis Carlos Blesa Baviera, Ester Donat, Luís Ortigosa, Néstor Litwin, Luis Peña Quintana, Virginia Méndez, Ma Victoria González, J. Manzanares López-Manzanares, Enrique Méndez, Carmen Ribes‐Koninckx,

ABSTRACT Objective: To assay the efficiency for celiac disease (CD) screening of 2 immunochromatographic visual stick assays based on human recombinant tissue transglutaminase (tTG). One was the antitissue transglutaminase antibodies (AtTGA) stick for IgA/G antibodies to tTG detection, the other was the AtTGA/antigliadin antibodies (AGA) stick for IgA antibodies for tTG and/or gliadins. Patients and Methods: In a prospective multicenter study, 4 pediatric gastroenterology units from Spain and 2 from ...

Tópico(s): Microscopic Colitis

2007 - Lippincott Williams & Wilkins | Journal of Pediatric Gastroenterology and Nutrition

Artigo Acesso aberto

Gabriel Ferreira de Almeida Paizani,

... Marsílio produz o Defensor Pacis para o imperador Luís da Baviera e ambos defendem a independência do poder temporal ...

Tópico(s): Classical Studies and Legal History

2007 - UNIVERSIDADE FEDERAL DO PARANÁ | Revista Vernáculo

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

José Antônio de C. R. de ́Souza,

... Ockham viveram seus últimos anos na corte de Luís da Baviera. Ambos opuseram-se aos papas da época. Entretanto, ...

Tópico(s): Libraries, Manuscripts, and Books

1995 - Editora da Pontifícia Universidade Católica do Rio Grande do Sul (EDIPUCRS) | Veritas (Porto Alegre)

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ana Paula Tavares Magalhães,

... particular precede o universal. Exilado na corte de Luís da Baviera em Munique a partir de 1328, deu início ...

Tópico(s): Seventeenth-Century Political and Philosophical Thought

2022 - UNIVERSIDADE DE SÃO PAULO | Intelligere

Artigo Acesso aberto Brasil Produção Nacional

Fabiano Arndt Araújo,

... Império e Papado reacendeu-se nas figuras de Luís IV da Baviera e João XXII. Nesse contexto, Marsílio Mainardini, professor da Universidade de Paris, optou por colocar-se ao lado de Luís IV em oposição ao pontífice, produzindo tratados cujo ...

Tópico(s): Historical Education and Society

2017 - UNIVERSIDADE FEDERAL DO PARANÁ | Revista Vernáculo

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maiara Destro Inácio, Mariana Campos Costa, Tayra Ferreira Oliveira Lima, Ingrid Delbone Figueiredo, Bruno Pereira Motta, Luís Carlos Spolidório, Renata Pires Assis, Iguatemy Lourenço Brunetti, Amanda Martins Baviera,

The pharmacological properties of pentoxifylline have been re-evaluated, particularly in chronic kidney disease in diabetes, favored by its anti-inflammatory action. Definitive evidences of renal outcomes are lacking, which indicates the need for investigation of novel mechanisms of action of pentoxifylline. We postulated that components associated with the metabolism of advanced glycation end products (AGEs) may be modulated by pentoxifylline, which consequently decreases the detrimental effects ...

Tópico(s): Adipokines, Inflammation, and Metabolic Diseases

2020 - Elsevier BV | Life Sciences

Artigo Revisado por pares

Inmaculada Campos, Rafael Masot, Miguel Alcañíz, Luís Gil, Juán Soto, José‐Luis Vivancos, Eduardo Garcı́a-Breijo, Roberto H. Labrador, José Manuel Barat Baviera, Ramón Martínez‐Máñez,

A method for predicting levels of chloride, nitrite and nitrate in minced meat by using an electronic tongue based on pulse voltammetry is proposed here. The electronic tongue consists of a set of noble (Au, Pt, Rh, Ir, Ag) and non-noble (Ni, Co, Cu) electrodes that were housed inside a stainless steel cylinder used at the same time as both the body of the electronic tongue system and the counter/reference electrode. An electrochemical study of the response of the anions Cl−, NO3− and NO2− using the ...

Tópico(s): Biochemical Analysis and Sensing Techniques

2010 - Elsevier BV | Sensors and Actuators B Chemical

Artigo Revisado por pares

Luís Gil, José Manuel Barat Baviera, Eduardo Garcı́a-Breijo, Javier Ibáñez, Ramón Martínez‐Máñez, Juán Soto, Eduard Llobet, J. Brezmes, M‐Concepción Aristoy, Fidel Toldrá,

One of the fields where the idea of developing artificial electronic mammalian sense devices might be widely applied is in food analysis. In this field, one very complex attribute yet of great importance is that of freshness. For instance, freshness is one of the most significant parameters of fish quality in most markets. The state of fish freshness can be assessed by various indicators but most of them are costly, time-consuming and lack of aptness for in situ or on site monitoring. This makes ...

Tópico(s): Advanced Chemical Sensor Technologies

2007 - Elsevier BV | Sensors and Actuators B Chemical

Artigo Acesso aberto Revisado por pares

Marina Campins‐Romeu, Raquel Baviera‐Muñoz, Isabel Sastre‐Bataller, Luís Bataller, Teresa Jaijo, Irene Martínez‐Torres,

Hereditary spastic paraplegias (HSP) are neurodegenerative disorders with significant clinical and genetic heterogeneity. To date, more than 80 causative loci of HSP have been identified, comprising autosomal dominant, autosomal recessive, X-linked and mitochondrial inheritance patterns.1 Spastic paraplegia type 7 (SPG7) is one of the most common autosomal recessive forms. SPG7 gene encodes paraplegin a mitochondrial metalloprotease involved in mitochondrial membrane trafficking, regulation of cell ...

Tópico(s): Neurological diseases and metabolism

2021 - Wiley | Movement Disorders Clinical Practice

Revisão Revisado por pares

Joel Girón‐Hernández, Luís Gil-Sánchez, Eduardo Garcı́a-Breijo, M. Jesús Pagán, José Manuel Barat Baviera, Raúl Grau,

Microbiological contamination in dry-cured ham can occur in the early stages of the process, a large number of microorganisms involved in spoilage can produce alterations in the product. These include non-common odours, which are detected at the end of the process by a procedure called "cala", consisting of a sharp instrument punctured in every ham; this is smelled by an expert taster, who classifies hams as good and altered hams. An electronic device would be suitable for this process given the ...

Tópico(s): Spectroscopy and Chemometric Analyses

2015 - Elsevier BV | Meat Science

Artigo Acesso aberto Revisado por pares

Raquel Baviera‐Muñoz, Lidón Carretero‐Vilarroig, Juan F. Vázquez‐Costa, Carlos Morata‐Martínez, Marina Campins‐Romeu, Nuria Muelas, Isabel Sastre‐Bataller, Irene Martínez‐Torres, Julia Pérez-García, Rafael Sivera, Teresa Sevilla, Juan J. Vílchez, Teresa Jaijo, Carmen Espinós, José M. Millán, Luís Bataller, Elena Aller,

To determine the diagnostic efficacy of clinical exome-targeted sequencing (CES) and spinocerebellar ataxia 36 (SCA36) screening in a real-life cohort of patients with cerebellar ataxia (CA) from Eastern Spain.A total of 130 unrelated patients with CA, negative for common trinucleotide repeat expansions (SCA1, SCA2, SCA3, SCA6, SCA7, SCA8, SCA12, SCA17, dentatorubral pallidoluysian atrophy [DRPLA], and Friedreich ataxia), were studied with CES. Bioinformatic and genotype-phenotype analyses were performed ...

Tópico(s): Neurological diseases and metabolism

2022 - Wolters Kluwer | Neurology Genetics

Artigo Revisado por pares

Raquel Baviera‐Muñoz, Marina Campins‐Romeu, Lidón Carretero‐Vilarroig, Isabel Sastre‐Bataller, Irene Martínez‐Torres, Juan F. Vázquez‐Costa, Nuria Muelas, Teresa Sevilla, Juan J. Vílchez, Elena Aller, Teresa Jaijo, Luís Bataller, Carmen Espinós,

Spastic paraplegia type 7 (SPG7) is one of the most common hereditary spastic paraplegias. SPG7 mutations most often lead to spastic paraparesis (HSP) and/or hereditary cerebellar ataxia (HCA), frequently with mixed phenotypes. We sought to clinically and genetically characterize a Spanish cohort of SPG7 patients. Patients were recruited from our HCA and HSP cohorts. We identified twenty-one patients with biallelic pathogenic SPG7 mutations. Mean age at onset was 37.4 years (SD ± 14.3). The most frequent ...

Tópico(s): Genetic Neurodegenerative Diseases

2021 - Elsevier BV | Journal of the Neurological Sciences

Artigo

Patricia Marrero Álvarez, Jesús Ruiz Ramos, Juan Eduardo Megías‐Vericat, María Tordera-Baviera, Jose Luís Poveda-Andrés,

Evaluar la calidad del contenido de la hoja de información al paciente (HIP) y del consentimiento informado (CI) en los ensayos clínicos. Estudio observacional retrospectivo. Se evaluaron 50 HIP de ensayos clínicos iniciados entre 2010 y 2011. La calidad de las hojas de información fue evaluada a través de las Guías de Buena Práctica Clínica presentes en la CPMP/ICH/135/95 de la Agencia Europea de Medicamentos. Se aplicaron índices de legibilidad a las HIP y al CI. El 10% de las HIP presentaban correctos ...

Tópico(s): Ethics and bioethics in healthcare

2012 - Elsevier BV | Revista de Calidad Asistencial

Artigo

Jesús Ruiz Ramos, Margarita Cueto-Sola, Ana García Robles, Pablo Pérez Huertas, María Tordera Baviera, José Luís Poveda Andrés,

Background and objective: Pharmacogenetic studies have become in recent years a common practice in the development of new drugs, with the need to evaluate the information and readability of Informed Consent Forms (ICFs) to ensure compliance with the recommendations set by current legislation and expert groups. Materials and methods: Retrospective observational study that analyzes the content of ICFs received by participants of pharmacogenetic studies approved in a tertiary hospital. To evaluate the ...

Tópico(s): Ethics in Clinical Research

2015 - Q106286904 | Cuadernos de bioética/Cuadernos de bioética

Artigo Revisado por pares

Baviera-Muñoz, D. Tarruella-Hernández, Luís Bataller,

La ataxia cerebelosa es un síndrome caracterizado por inestabilidad de la marcha, pérdida de coordinación y alteraciones oculomotoras y del habla. Son enfermedades muy heterogéneas clínica y genéticamente. Se han descrito más de 200 genes causales y se requieren distintas técnicas para analizar los diferentes tipos de mutaciones: expansiones dinámicas, mutaciones puntuales o variaciones en el número de copias. La aplicación en los últimos años de las nuevas técnicas de secuenciación genética masiva ...

Tópico(s): Genomics and Rare Diseases

2023 - Elsevier BV | Medicine - Programa de Formación Médica Continuada Acreditado

Artigo Acesso aberto Revisado por pares

Raquel Baviera‐Muñoz, Lidón Carretero‐Vilarroig, Nuria Muelas, Rafael Sivera, Pablo Sopena‐Novales, Begoña Martínez‐Sanchis, Isabel Sastre‐Bataller, Marina Campins‐Romeu, Irene Martínez‐Torres, José Manuel García‐Verdugo, José M. Millán, Teresa Jaijo, Elena Aller, Luís Bataller,

Autosomal dominant spinocerebellar ataxia 36 (SCA36) is caused by hexanucleotide repeat expansion in the NOP56 gene.To assess frequency, clinical and genetic features of SCA36 in Eastern Spain.NOP56 expansion was tested in a cohort of undiagnosed cerebellar ataxia families (n = 84). Clinical characterization and haplotype studies were performed.SCA36 was identified in 37 individuals from 16 unrelated families. It represented 5.4% of hereditary ataxia patients. The majority were originally from the same ...

Tópico(s): DNA Repair Mechanisms

2023 - Wiley | Movement Disorders Clinical Practice

Artigo Brasil Produção Nacional Revisado por pares

Rafael Masot, Miguel Alcañíz, Ana Fuentes, Franciny Campos, José Manuel Barat Baviera, Luís Gil, Roberto H. Labrador, Juán Soto, Ramón Martínez‐Máñez, Matteo Pardo, Giorgio Sberveglieri,

The IQMA and the DTA have developed a low‐cost system to determinate the contents of water and salt in food products as cured ham or pork loin using non‐destructive methods. The system includes an electronic equipment that allows the implementation of impedance spectroscopy and an electrode. The electrode is a concentric needle which allows carrying out tests in a non‐destructive way. Preliminary results indicate that there is a correlation between the water and salt contents and the module and ...

Tópico(s): Spectroscopy and Chemometric Analyses

2009 - American Institute of Physics | AIP conference proceedings

Artigo Acesso aberto Revisado por pares

Raquel Baviera‐Muñoz, Lidón Carretero‐Vilarroig, Ana Pedro‐Ibor, Teresa Jaijo, Andrea Del Valle‐Carranza, Irene Martínez‐Torres, José M. Millán, Luís Bataller, Elena Aller,

Abstract Background Spinocerebellar ataxia type 8 (SCA8) is a dominantly inherited expansion disorder with highly variable penetrance. ATXN8OS/ATXN8 expanded alleles have been identified in association with other types of hereditary ataxias, pointing to a possible genetic synergism. Objectives We aimed to further investigate the molecular background of patients with SCA8 diagnosis. Methods Patients were selected from our cohort of 346 families. A total of 14 probands with SCA8 underwent additional ...

Tópico(s): Nuclear Structure and Function

2024 - Wiley | Movement Disorders

Artigo Acesso aberto Revisado por pares

Isabel Font Noguera, José Luís Poveda Andrés, V. Lerma Gaude, Eduardo San Martín Ciges, M. Tordera Baviera, Carmen Planells Herrero,

Evaluar la calidad en la atención farmacéutica al paciente hospitalizado a través de criterios cualitativos establecidos en el programa Valor®. Estudio de evaluación a través de 43 criterios explícitos estructurales, de proceso y de resultado incluidos en el programa Valor® que valoran los propios farmacéuticos de la unidad functional de dosis unitarias, en una escala de cumplimiento del 0 a 100%. Dicha unidad proporciona atención farmacéutica individualizada diariamente a 550 pacientes, pertenecientes ...

Tópico(s): Health Systems, Economic Evaluations, Quality of Life

2006 - Sociedad Española de Farmacia Hospitalaria | Farmacia Hospitalaria

Artigo Acesso aberto Revisado por pares

Marina Campins‐Romeu, Rebeca Conde-Sardón, Isabel Sastre‐Bataller, Carlos Morata‐Martínez, Mireya Losada-López, José Luís León-Guijarro, Luis Raga-Rodríguez, Julia Pérez-García, Antonio Gutiérrez-Martín, Andrés M. Lozano, Raquel Baviera‐Muñoz, Irene Martínez‐Torres,

Idiopathic Parkinson's Disease (PD) is a neurodegenerative disorder characterized by tremor, rigidity, bradykinesia, and postural instability. Magnetic Resonance-guided high-intensity focused ultrasound (MRgFUS) of the subthalamic nucleus (STN) is gaining recognition as a minimally invasive surgical option. This study assesses the safety and efficacy of unilateral MRgFUS subthalamotomy, aiming to create the smallest effective lesion. Between June 2021 and October 2023, twelve PD patients underwent ...

Tópico(s): Botulinum Toxin and Related Neurological Disorders

2024 - Nature Portfolio | npj Parkinson s Disease

Artigo Acesso aberto Revisado por pares

José M. Castellano, Ginés Sanz, José L. Peñalvo, Sameer Bansilal, Antonio Fernández-Ortı́z, Luz María de Guadalupe González Álvarez, Luís Guzmán, Juan Carlos Linares, Fernando Flores García, Fabiana D’Aniello, Joan Albert Arnáiz, Sara Varea, Felipe A. Martínez, Alberto J. Lorenzatti, Iñaki Imaz-Iglesia, Luis María Sánchez-Gómez, Maria Carla Roncaglioni, Marta Baviera, Sidney C. Smith, Kathryn A. Taubert, Stuart J. Pocock, Carlos Brotons, Michael E. Farkouh, Valentı́n Fuster,

Adherence to evidence-based cardiovascular (CV) medications after an acute myocardial infarction (MI) is low after the first 6 months. The use of fixed-dose combinations (FDC) has been shown to improve treatment adherence and risk factor control. However, no previous randomized trial has analyzed the impact of a polypill strategy on adherence in post-MI patients.The cross-sectional FOCUS (Fixed-Dose Combination Drug for Secondary Cardiovascular Prevention) study (Phase 1) aimed to elucidate factors that ...

Tópico(s): Bipolar Disorder and Treatment

2014 - Elsevier BV | Journal of the American College of Cardiology