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Artigo Revisado por pares

John G. Jones, Cristina Barosa, Filipe Coreta‐Gomes, Ana C. Mendes, Teresa C. Delgado, Luísa Diogo, Paula Garcia, Margarida Bastos, Luísa Barros, Ana Fagulha, Carla Baptista, Manuela Carvalheiro, M. Madalena Caldeira,

Quantification of 2H and 13C enrichment distributions in human urinary glucuronide following ingestion of 2H2O and 13C gluconeogenic tracers was achieved by NMR spectroscopy of the 1,2‐O‐isopropylidene‐α‐D‐glucofuranurono‐6,3‐lactone and 5‐O‐acetyl‐1,2‐O‐isopropylidene‐α‐D‐glucofuranurono‐6,3‐lactone derivatives. The derivatization process is simple and can be applied to any glucuronide species. The derivatives are highly soluble in acetonitrile and generate well‐resolved and narrow 2H and 13C NMR ...

Tópico(s): Analytical Chemistry and Chromatography

2006 - Taylor & Francis | Journal of Carbohydrate Chemistry

Artigo Brasil Produção Nacional Revisado por pares

Aliny Pontes Almeida, Arlei Marcili, Romário Cerqueira Leite, Fernanda A. Nieri-Bastos, Luísa N. Domingues, Ricardo Marcondes Martins, Marcelo B. Labruna,

In the present study, the presence of tick-associated bacteria and protozoa in Ornithodoros rostratus ticks (adults, nymphs, and eggs) from the Pantanal region of Brazil were determined by molecular detection. In these ticks, DNA from protozoa in the genera Babesia and Hepatozoon, and bacteria from the genera Rickettsia, Borrelia, Anaplasma, and Ehrlichia were not detected. Conversely, all tested ticks (100%) yielded PCR products for 3 Coxiella genes (16S rRNA, pyrG, cap). PCR and phylogenetic analysis ...

Tópico(s): Insect symbiosis and bacterial influences

2012 - Elsevier BV | Ticks and Tick-borne Diseases

Artigo Brasil Produção Nacional Revisado por pares

Philipe Costa, Thaise Boeing, Líncon Bordignon Somensi, Benhur Judah Cury, Vanessa Lopes Espíndola, Tauani Caroline Santos França, Marília Oliveira de Almeida, Caroline Arruda, Jairo Kenupp Bastos, Luísa Mota da Silva, Sérgio Faloni de Andrade,

Abstract Baccharis dracunculifolia is a medicinal plant native to southeastern Brazil and is the main botanical source used by bees ( Apis mellifera ) in the manufacture of green propolis and display similar gastroprotective action and chemical profile. This article reports the healing gastric ulcer activity of the hydroethanolic extract of B. dracunculifolia (HEBD) in an acetic acid‐induced ulcer model. In addition to the extract, the isolated compounds ferulic acid, p ‐coumaric acid, caffeic acid, baccharin, ...

Tópico(s): Insect Pest Control Strategies

2019 - Wiley | BioFactors

Artigo Brasil Produção Nacional Revisado por pares

Philipe Costa, Marília Oliveira de Almeida, Marivane Lemos, Caroline Arruda, Rosana Casoti, Líncon Bordignon Somensi, Thaise Boeing, Marihá Mariott, Rita de Cássia Melo Vilhena de Andrade Fonseca da Silva, Bruna De Paoli Stein, Priscila de Souza, Ana Caroline dos Santos, Jairo Kenupp Bastos, Luísa Mota da Silva, Sérgio Faloni de Andrade,

The propolis is extensively used in folk medicine in natura or to prepare pharmaceutical formulations since ancient time to improve health or prevent diseases, among them gastrointestinal disorders. Aiming to contribute in the scientific validation about the popular use of Brazilian Green propolis (BGP) against gastritis and gastric ulcer, this work evaluated the antiulcer potential of isolated compounds from BGP, three prenylated p-coumaric acid derivatives and two flavonoids, respectively named: ...

Tópico(s): Moringa oleifera research and applications

2018 - Elsevier BV | Journal of Ethnopharmacology

Revisão Acesso aberto Revisado por pares

Nelson Soares, Joana Bastos, Luísa Dias Pereira, Ana Soares, Ana Rita Amaral, Ehsan Asadi, Eugénio Rodrigues, Francisco B. Lamas, Helena Monteiro, Marta A. R. Lopes, Adélio Rodrigues Gaspar,

Nowadays, debates addressing climate change, fossil fuels depletion and energy security highlight the need for a more sustainable built environment in order to reduce energy consumption and emission trends in the buildings sector. Meeting these targets is a challenge that calls for innovative research to improve the use of renewable energy sources, new technologies, and holistic tools and methodologies. Such research should integrate the dynamics and main drivers of energy supply and demand in buildings ...

Tópico(s): Sustainable Building Design and Assessment

2017 - Elsevier BV | Renewable and Sustainable Energy Reviews

Artigo Acesso aberto Revisado por pares

Catarina Gonçalves, José Maria Aragüés, Margarida Bastos, Luísa Barros, Nuno Vicente, Davide Carvalho, Manuel C. Lemos,

Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare disorder characterised by lack of pubertal development and infertility, due to deficient production, secretion or action of gonadotropin-releasing hormone (GnRH) and, unlike Kallmann syndrome, is associated with a normal sense of smell. Mutations in the GNRHR gene cause autosomal recessive nCHH. The aim of this study was to determine the prevalence of GNRHR mutations in a group of 40 patients with nCHH.Cross-sectional study of 40 ...

Tópico(s): Sexual Differentiation and Disorders

2017 - Bioscientifica | Endocrine Connections

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Jasmin K. Schuster, Tom Harner, Gilberto Fillmann, Lutz Ahrens, Jorgelina C. Altamirano, Beatriz Helena Aristizábal Zuluaga, Wanderley Rodrigues Bastos, Luisa E. Castillo, J. Elena Cortés, Oscar Fentanes, Alexey Gusev, Maricruz Hernandez, Martı́n Villa Ibarra, Nerina Belén Lana, Sum Chi Lee, A. Martinez, Karina S.B. Miglioranza, Andrea Padilla Puerta, Federico Segovia, May Siu, Maria Yumiko Tominaga,

A passive air sampling network has been established to investigate polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) at Global Atmospheric Passive Sampling (GAPS) sites and six additional sites in the Group of Latin American and Caribbean Countries (GRULAC) region. The air sampling network covers background, agricultural, rural, and urban sites. Samples have been collected over four consecutive periods of 6 months, which started in January 2011 [period 1 (January to June ...

Tópico(s): Air Quality and Health Impacts

2015 - American Chemical Society | Environmental Science & Technology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gisele Alsina Nader Bastos, Luísa Rabeno Fasolo,

To measure the prevalence of overall satisfaction with the previous medical consultation and their associated factors, among adults aged 20 years or more, in a city located in southern Brazil.A cross-sectional population-based study was performed in Porto Alegre, RS, Brazil, from July to December 2009. Systematic sampling was used with a probability proportional to the size of each of the 121 census tracts in the area studied. Overall satisfaction with the previous consultation was evaluated with ...

Tópico(s): Patient-Provider Communication in Healthcare

2013 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia

Artigo Acesso aberto Revisado por pares

Manuel C. Lemos, Ana Fagulha, Eduarda Coutinho, Leonor Gomes, Margarida Bastos, Luísa Barros, Francisco Carrilho, E Geraldes, Fernando Regateiro, Manuela Carvalheiro,

The vitamin D receptor (VDR) gene is a candidate gene for susceptibility to autoimmune disorders. Association studies of VDR polymorphisms and risk of type 1 diabetes often produced conflicting results in different ethnic backgrounds. The aim of this study was to test for association between common VDR polymorphisms and the genetic susceptibility to type 1 diabetes in the Portuguese population. We genotyped 207 patients with type 1 diabetes and 249 controls for the FokI T>C (rs10735810), BsmI A>G ( ...

Tópico(s): Digestive system and related health

2008 - Elsevier BV | Human Immunology

Artigo Acesso aberto Revisado por pares

John G. Jones, Ana Fagulha, Cristina Barosa, Margarida Bastos, Luísa Barros, Carla Baptista, M. Madalena Caldeira, Manuela Carvalheiro,

The contributions of hepatic glycogenolysis to fasting glucose production and direct pathway to hepatic glycogen synthesis were quantified in eight type 1 diabetic patients and nine healthy control subjects by ingestion of (2)H(2)O and acetaminophen before breakfast followed by analysis of urinary water and acetaminophen glucuronide. After overnight fasting, enrichment of glucuronide position 5 relative to body water (G5/body water) was significantly higher in type 1 diabetic patients compared with ...

Tópico(s): Metabolism and Genetic Disorders

2006 - American Diabetes Association | Diabetes

Artigo Acesso aberto Revisado por pares

Ana Basto, Luísa M.P. Valente, Marta Conde‐Sieira, José L. Soengas,

The homeostatic regulation of food intake in fish has been thoroughly studied in the last years with dietary nutrient composition is one of the factors involved. Despite several studies addressed the impact of insect meal-based diets in food intake of fish, there is no knowledge about their impact in mechanisms of food intake regulation. This study aimed to explore underlying mechanisms through evaluation of dietary fishmeal (FM) replacement by defatted (d-) Tenebrio molitor (dTM) larvae meal in European ...

Tópico(s): Neurobiology and Insect Physiology Research

2021 - Elsevier BV | Aquaculture

Artigo Acesso aberto Revisado por pares

Willian Melo, José L. S. Pinho, Isabel Iglesias, Ana Bio, Paulo Avilez‐Valente, José Vieira, Luísa Bastos, Fernando Veloso Gomes,

The understanding and anticipating of climate change impacts is one of the greatest challenges for humanity. It is already known that, until the end of the 21st century, the mean sea level (MSL) will rise at a global scale, but its effects at the local scale need to be further analyzed. In this context, a numerical modelling tool and a methodological approach for the river Minho estuary (NW of the Iberian Peninsula) are presented, to predict possible consequences of local MSL rise, considering the ...

Tópico(s): Oceanographic and Atmospheric Processes

2020 - Multidisciplinary Digital Publishing Institute | Journal of Marine Science and Engineering

Artigo Acesso aberto Revisado por pares

Joana Fernandes da Rocha, Luísa Bastos, Sara C. Domingues, Ana Rita Bento, Uwe Konietzko, Odete A. B. da Cruz e Silva, Sandra I. Vieira,

The amyloid precursor protein (APP) is a transmembrane glycoprotein central to Alzheimer’s disease (AD) with functions in brain development and plasticity, including in neurogenesis and neurite outgrowth. Epidermal growth factor (EGF) and heparin-binding EGF-like growth factor (HB-EGF) are well-described neurotrophic and neuromodulator EGFR ligands, both implicated in neurological disorders, including AD. Pro-HB-EGF arose as a putative novel APP interactor in a human brain cDNA library yeast two-hybrid ...

Tópico(s): Glycosylation and Glycoproteins Research

2020 - Springer Science+Business Media | Molecular Neurobiology

Artigo Acesso aberto Revisado por pares

Walter E.C. Pritzkow, Renato S.M. Almeida, Luisa Bastos Mateus, Kamen Tushtev, Kurosch Rezwan,

Cost reduction without loss of quality is a key factor during the development of engineering materials. This is particularly true for oxide fibers, which can represent up to 70 % of the real cost of all-oxide ceramic matrix composites (OCMC). Therefore, the objective of this work is to produce and evaluate OCMCs based on novel low-cost Nextel™ 610 fiber fabrics with deniers of 3000−20,000. Experiments were divided into fiber and composite characterizations. In general, fiber bundles with higher denier ...

Tópico(s): Additive Manufacturing and 3D Printing Technologies

2020 - Elsevier BV | Journal of the European Ceramic Society

Artigo Acesso aberto Revisado por pares

Wenlin Yan, Luísa Bastos, Américo Magalhães,

We have been focused on the exploitation of the limits of the performance of low cost sensors, used in an integrated way, both for classical and geodetic navigation. In this work, the navigation performance of the Android smartphone's IMU was assessed thoroughly. The raw IMU data from two smartphones, "Xiaomi 8" and "Honor Play" were recorded, using different sampling rates, and compared with the measurements, recorded simultaneously from higher grade IMU's. For assessing the navigation capabilities ...

Tópico(s): Context-Aware Activity Recognition Systems

2019 - Institute of Electrical and Electronics Engineers | IEEE Access

Artigo Acesso aberto Revisado por pares

Isabel Iglesias, Paulo Avilez‐Valente, Ana Bio, Luísa Bastos,

Numerical models are key tools to characterize hydrodynamical patterns of coastal environments and anticipate the potential effects of hazardous and extreme events, anthropogenic intervention or climate change. In this work, the openTELEMAC-MASCARET modelling system was selected to represent the dynamics of the Minho estuary, a very shallow estuary located at the Northwestern Iberian Peninsula coast. Calibration and validation results confirm the accuracy of the numerical tool, with small root mean ...

Tópico(s): Tropical and Extratropical Cyclones Research

2019 - Multidisciplinary Digital Publishing Institute | Water

Artigo Revisado por pares

Carina L. Lopes, Luísa Bastos, Miguel Caetano, Irene Martins, Miguel M. Santos, Isabel Iglesias,

Deep-sea mining has gained international interest to provide materials for the worldwide industry. European oceans and, particularly, the Portuguese Exclusive Economic Zone present a recognized number of areas with polymetallic sulphides rich in metals used in high technology developments. A large part of these resources are in the vicinity of sensitive ecosystems, where the mineral extraction can potentially damage deep-ocean life services. In this context, technological research must be intensified, ...

Tópico(s): Geological formations and processes

2018 - Elsevier BV | The Science of The Total Environment

Artigo Acesso aberto Revisado por pares

Magda Magalhães, Lígia Basto, Ana Luísa Areia, Sofia Franco, Maria Eugénia Malheiro, Maria Eulália Afonso, Paulo Moura,

Purpose To evaluate maternal-fetal surveillance and follow-up of infants at risk for congenital syphilis (CS). Methods Retrospective cohort study in a Portuguese Tertiary Referral Hospital. The main inclusion criterion was a positive syphilis serology. The study included all pregnant women that delivered in our hospital between January 2004 and December 2013. The neonates were classified according to their probability of infection based on the Centers for Disease Control and Prevention guidelines. ...

Tópico(s): Female Genital Mutilation/Cutting Issues

2017 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia

Artigo Revisado por pares

Catarina Basto-Silva, Luísa M.P. Valente, Elisabete Matos, Miguel Brandão, Belmira Neto,

Tópico(s): Marine and fisheries research

2017 - Springer Science+Business Media | The International Journal of Life Cycle Assessment

Artigo Revisado por pares

Isabel Iglesias, M. N. Lorenzo, Clara Lázaro, M. Joana Fernandes, Luísa Bastos,

Sea level anomaly (SLA), provided globally by satellite altimetry, is considered a valuable proxy for detecting long-term changes of the global ocean, as well as short-term and annual variations. In this manuscript, monthly sea level anomaly grids for the period 1993-2013 are used to characterise the North Atlantic Ocean variability at inter-annual timescales and its response to the North Atlantic main patterns of atmospheric circulation variability (North Atlantic Oscillation, Eastern Atlantic, Eastern ...

Tópico(s): Oceanographic and Atmospheric Processes

2017 - Elsevier BV | The Science of The Total Environment

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

João Soares Felício, Alana Ferreira de Oliveira, Amanda Soares Peixoto, Ana Carolina Contente Braga de Souza, João Felício Abrahão Neto, Franciane Trindade Cunha de Melo, Carolina Tavares Carvalho, Manuela Nascimento de Lemos, Sávio Diego Nascimento Cavalcante, Fabrício de Souza Resende, Márcia Costa dos Santos, Ana Regina Bastos Motta, Luísa Corrêa Janaú, Elizabeth Sumi Yamada, Karem Miléo Felício,

Some studies suggest an association between diabetic kidney disease (DKD) and vitamin D (VD), but there is no data about the effect of high dose of VD on DKD in type 1 diabetes mellitus (T1DM). Our pilot study aims to evaluate albuminuria reduction in patients with T1DM supplemented with high dose of VD.22 patients received doses of 4,000 and 10,000 IU/day of cholecalciferol for 12 weeks according to patient's previous VD levels. They were submitted to continuous glucose monitoring system, 24 hours ...

Tópico(s): Electrolyte and hormonal disorders

2017 - Frontiers Media | Frontiers in Endocrinology

Artigo Acesso aberto Revisado por pares

Luísa Bastos, Ana Bio, Isabel Iglesias,

Coastal and Oceanic Observatories are important tools to provide information on ocean state, phenomena and processes. They meet the need for a better understanding of coastal and ocean dynamics, revealing regional characteristics and vulnerabilities. These observatories are extremely useful to guide human actions in response to natural events and potential climate change impacts, anticipating the occurrence of extreme weather and oceanic events and helping to minimize consequent personal and material ...

Tópico(s): Ocean Acidification Effects and Responses

2016 - Frontiers Media | Frontiers in Marine Science

Artigo Revisado por pares

David Becker, J. Emil Nielsen, Diogo Ayres-Sampaio, R. Forsberg, Matthias Becker, Luísa Bastos,

Tópico(s): GNSS positioning and interference

2015 - Springer Science+Business Media | Journal of Geodesy

Artigo Acesso aberto Revisado por pares

Joaquim J. Sousa, Ivana Hlaváčová, Matúš Bakoň, Milan Lazecký, Glória Patrício, Pedro Guimarães, Antonio M. Ruiz‐Armenteros, Luísa Bastos, António Sousa, Ricardo Bento,

The aim of this paper is twofold. Firstly, to present a survey of the actual and most advanced methods for man-made structures monitoring, more specifically dams and bridges. Theoretical and technical aspects of these methodologies are presented and discussed focusing on innovative inspection methods and on the opportunities that could deliver. Secondly, to identify the opportunities that could potentially improve the inspections and maintenance processes, being the satellite-based monitoring, using ...

Tópico(s): Landslides and related hazards

2014 - Elsevier BV | Procedia Technology

Artigo Acesso aberto Revisado por pares

Sérgio Madeira, José Alberto Gonçalves, Luísa Bastos,

Mobile mapping is a multidisciplinary technique which requires several dedicated equipment, calibration procedures that must be as rigorous as possible, time synchronization of all acquired data and software for data processing and extraction of additional information. To decrease the cost and complexity of Mobile Mapping Systems (MMS), the use of less expensive sensors and the simplification of procedures for calibration and data acquisition are mandatory features. This article refers to the use ...

Tópico(s): Inertial Sensor and Navigation

2012 - Multidisciplinary Digital Publishing Institute | Sensors

Artigo Revisado por pares

Yanrui Geng, Richard Deurloo, Luísa Bastos,

Tópico(s): Target Tracking and Data Fusion in Sensor Networks

2010 - Springer Science+Business Media | GPS Solutions

Artigo Revisado por pares

M. Joana Fernandes, Clara Lázaro, Alexandra L. Nunes, Nelson Pires, Luísa Bastos, V. B. Mendes,

This letter presents an innovative method for computing the wet tropospheric correction for altimetry measurements in the coastal regions, where the measurements from the microwave radiometers (MWRs) onboard altimetric missions become invalid. The method, called Global Navigation Satellite System (GNSS)-derived Path Delay, gives an estimation of the correction, along with the associated mapping error, from the combination of independent zenith wet delay (ZWD) values obtained from the tropospheric delays ...

Tópico(s): Ionosphere and magnetosphere dynamics

2010 - Institute of Electrical and Electronics Engineers | IEEE Geoscience and Remote Sensing Letters