Manuel R. Agosín, María Luisa Dinamarca,
1. The levels of oxidized and reduced pyridine nucleotides have been measured in normal and DDT- and DDE-treated nymphs and adult males of T. infestans. 2. The total content of DPN (DPN plus DPNH) is higher than TPN (TPN plus TPNH) in both nymphs and males. In nymphs, DPN is mainly present in the oxidized form and TPN in the reduced form, while in males TPN is mainly found in the reduced form and DPN in the oxidized form. 3. DDT significantly increases the total TPN content in nymphs, but does not ...
Tópico(s): Diet, Metabolism, and Disease
1963 - Elsevier BV | Experimental Parasitology
G. S. Hodgson, Siegmund Fischer, M Perretta, I. Eskuche, Guillermo Antonio Diaz Araya, María Luisa Dinamarca,
Abstract Methods are described for the separation of nondialyzable material with erythropoietic activity (urinary hemopoietine), from urine of rabbits made anemic (< 5g Hb/100) by phenylhydrazine and of patients with aplastic anemia (< 5g Hb/100). The material obtained was assayed for its effects on Fe59 distribution 3 and 24 hours after tracer injection. The active extracts produced a marked increase in the rate of Fe59 clearance from plasma, and in the fraction of the injected Fe59 appearing in erythrocytes ...
Tópico(s): Blood transfusion and management
1960 - Elsevier BV | Blood
Moisés Agosı́n, N. Scaramelli, María Luisa Dinamarca, Luisa Aravena,
Tópico(s): Liver Disease Diagnosis and Treatment
1963 - Pergamon Press | Comparative Biochemistry and Physiology
Jovita Ilevicky, María Luisa Dinamarca, Manuel R. Agosín,
1. DDT and various compounds icnrease the in vivo concentration of NAD-kinase in T. infestants nymphs. On the other hand, other compounds are inhibitory. The effect of DDt is observed only with internal concentrations of approximately 15 μg, while lower concentrations inhibit the enzyme. NAD-kinase is induced more rapidly with DDD and DDT. The inductive effect is not permanent since, upon removal of DDT, NAD-kinase activity decreases. 2. The activation of NAD-kinase by DDT and some analogs as well ...
Tópico(s): Coenzyme Q10 studies and effects
1964 - Pergamon Press | Comparative Biochemistry and Physiology
María Luisa Dinamarca, Moisés Agosı́n, A Neghme,
(1) Nymph and male T. infestans specimens differ in their rate of absorption, excretion and metabolism of C14-DDT. Nymphs absorb DDT to a lesser extent than males. Furthermore, DDT is excreted at a faster rate in nymphs than males. After 96 hours of intoxication, 27.5% of the absorbed DDT is converted to a mixture of five metabolites in nymphs, while only 4.7% of the absorbed DDT is accounted for by DDT-metabolites in males after the same time of intoxication. (2) DDT is metabolized into five metabolites ...
Tópico(s): Circadian rhythm and melatonin
1962 - Elsevier BV | Experimental Parasitology
Eva Hertrampf, María Luisa Dinamarca, S Llaguno, A Stekel,
Recent evidence suggests that iron in human milk has a high bio-availability and that breast fed term infants are protected from developing iron deficiency during the first 6 months of life. Iron nutrition was determined in healthy term infants of low socioeconomic condition receiving breast milk as the only milk source for 4, 6 and 9 months (60, 70 and 31 subjects respectively) and compared with infants fed non fortified cow's milk. At 4 months, breast fed infants had a better iron nutrition status ...
Tópico(s): Indigenous Health and Education
1981 - Springer Nature | Pediatric Research
F. Dinamarca, M. Grifell, Alexandre Palma, Mijail Epifanio Andia Ventura, I. Fornís, Liliana Galindo, Luisa González, Marta Torrens, Vicente Borja Alvarez Pérez,
Synthetic cannabinoids, recently used as alternatives to Cannabis sativa, are among the most frequently abused drugs. Identified in 2014, the synthetic cannabinoids N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (5F-AB-PINACA) and methyl [1-(5-fluoropentyl)-1H-indazole-3-carbonyl]-valinate (5F-AMB) are carboxamides composed of 1-(5-fluoropentyl)-1H-indazole-3-carboxylic acid and valine amide/methyl ester. Because of their composition, these molecules have pairs of ...
Tópico(s): Psychedelics and Drug Studies
2016 - Elsevier BV | European Neuropsychopharmacology