Produção Nacional
Revisado por pares
Kayo Henrique Jardel Feitosa Sousa, Danilo de Paiva Lopes, Gisele Massante Peixoto Tracera, Ângela Maria Mendes Abreu, Luciana Fernandes Portela, Regina Célia Gollner Zeitoune,
Resumo Objetivo: Verificar as associações entre as variáveis sociodemográficas, laborais e condições de saúde e hábitos de vida e os transtornos mentais comuns entre os trabalhadores de enfermagem de um hospital psiquiátrico. Métodos: Estudo transversal, quantitativo, realizado em um hospital psiquiátrico. Participaram 74 trabalhadores de enfermagem. A coleta dos dados ocorreu por meio de questionário para caracterização sociodemográfica, laboral e de condições de saúde e hábitos de vida, da subescala ...
Tópico(s): Health, Nursing, Elderly Care
2019 - UNIVERSIDADE FEDERAL DE SÃO PAULO | Acta Paulista de Enfermagem
Produção Nacional
Revisado por pares
Fernanda S. Correia‐Melo, Gustavo C. Leal, Michelle S. Carvalho, Ana Paula Jesus‐Nunes, Carolina Barbosa Ferreira, Flávia Vieira, Guilherme Magnavita, Lucas A.S. Vale, Rodrigo P. Mello, Carolina Nakahira, Felipe Coelho Argôlo, Tanise L Cardoso, CEZAR DANIEL SNAK DE SOUZA, Ana Teresa Caliman‐Fontes, Marcelo B. Ferreira, Lucas Araújo-de-Freitas, Marco Aurélio Tuena, Mariana V.F. Echegaray, Diogo Esmeraldo Cavalcanti, Ana Cecília Lucchese, Igor D. Bandeira, Manuela Telles, Cassio Santos‐Lima, Aline S. Sampaio, Samantha S. Silva, Roberta Ferrari Marback, José Alberto Del-Porto, José Neander Abreu, Luciana Maria Sarin, Camilla S. Paixão, Lucas P. Carvalho, Paulo Roberto Lima Machado, Gustavo Turecki, Acioly L.T. Lacerda, Lucas C. Quarantini,
Introduction: The use of ketamine as an option in the treatment of depressive disorder is growing rapidly, supported by numerous clinical trials attesting its efficacy and safety. Esketamine, the S (+) enantiomer of ketamine, is the most widely used form in the anesthetic environment in some countries, and new studies have shown that it may also be effective in depression and with better tolerability. However, no study so far has directly compared esketamine with racemic ketamine. Here we propose a ...
Tópico(s): Mental Health Research Topics
2018 - Wolters Kluwer | Medicine
Produção Nacional
Revisado por pares
Raul Hernandes Bortolin, Francisco Paulo Freire Neto, Carlos Alberto Arcaro, João Felipe Bezerra, Flávio Santos da Silva, Marcela Abbott Galvão Ururahy, Karla Simone Costa de Souza, Valéria Morgiana Gualberto Duarte Moreira Lima, André Ducati Luchessi, Francisco Pignataro Lima, Marcus Vinícius Lia Fook, Bartolomeu Jorge da Silva, Maria das Graças Almeida, Bento João Abreu, Luciana Augusto de Rezende, Adriana Augusto de Rezende,
Type 1 diabetes mellitus (T1DM) is associated with several skeletal alterations, particularly in conditions of poor glycaemic control. Insulin therapy is the major conservative treatment for T1DM; however, the effects of this hormone on bone markers of T1DM rats are limited, and the regulatory mechanisms remain elusive. Therefore, the evaluation of molecular and non-molecular parameters in a chronic animal model of T1DM-induced bone loss, treated with and without insulin, may help in elucidating ...
Tópico(s): Bone health and osteoporosis research
2016 - Wiley | Basic & Clinical Pharmacology & Toxicology
Produção Nacional
Revisado por pares
Heitor A. De Abreu, Luciana Guimarães, Hélio A. Duarte,
Fe(III) hydrolysis in aqueous solution has been investigated using density-functional methods (DFT). All possible structures arising from different tautomers and multiplicities have been calculated. The solvation energy has been estimated using the UAHF−PCM method. The hydrolysis free energies have been estimated and compared with the available experimental data. The different hydrolysis species have distinct geometries and electronic structures. We have shown that improvement of theory level in ...
Tópico(s): Iron oxide chemistry and applications
2006 - American Chemical Society | The Journal of Physical Chemistry A
Produção Nacional
Revisado por pares
Rosa Maria Chura‐Chambi, Álvaro Rossan de Brandão Prieto da Silva, Matheus Martins Di Lela, João Ezequiel Oliveira, Patricia Estima Antonia Abreu, Luciana Regina Meireles, Heitor Franco de Andrade, Lígia Morganti,
SARS-CoV-2 Nucleocapsid (N) is the most abundant viral protein expressed in host samples and is an important antigen for diagnosis. N is a 45 kDa protein that does not present disulfide bonds. Intending to avoid non-specific binding of SARS-CoV-2 N to antibodies from patients who previously had different coronaviruses, a 35 kDa fragment of N was expressed without a conserved motif in E. coli as inclusion bodies (N122-419-IB). Culture media and IB washing conditions were chosen to obtain N122-419-IB ...
Tópico(s): Viral gastroenteritis research and epidemiology
2022 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Cécilia Bohns Michalowski, Marcelo Dutra Arbo, Louise Altknecht, Andréia N. Anciuti, Angélica S. G. Abreu, Luciana Magalhães Rebêlo Alencar, Adriana Raffin Pohlmann, Solange Cristina García, Sı́lvia Stanisçuaski Guterres,
Multi-wall lipid-core nanocapsule (MLNC) functionalized with captopril and nanoencapsulating furosemide within the core was developed as a liquid formulation for oral administration. The nanocapsules had mean particle size below 200 nm, showing unimodal and narrow size distributions with moderate dispersity (laser diffraction and dynamic light scattering). Zeta potential was inverted from −14.3 mV [LNC-Fur(0,5)] to +18.3 mV after chitosan coating. Transmission electron microscopy and atomic force microscopy ...
Tópico(s): Advanced Drug Delivery Systems
2020 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Produção Nacional
Revisado por pares
Cláudia Regina Lindgren Alves, Soraya Almeida Belisário, José Maurício Carvalho Lemos, Daisy Maria Xavier de Abreu, Luciana de Souza D'Ávila, Lúcia Maria Horta Figueiredo Goulart,
O estudo tem como objetivo discutir as dificuldades enfrentadas pelas escolas médicas para implementação de mudanças curriculares no contexto do Programa de Incentivo a Mudanças Curriculares nas Escolas de Medicina - PROMED. Foram realizados entrevistas com dirigentes dos cursos de medicina e com gestores locais do SUS, além de grupos focais com alunos e professores. Os principais fatores dificultadores observados dizem respeito aos docentes, estudantes, instituição de ensino, serviços/gestão do SUS ...
Tópico(s): Public Health in Brazil
2013 - Associção Brasileira de Educação Médica | Revista Brasileira de Educação Médica
Produção Nacional
Revisado por pares
Heitor A. De Abreu, Luciana Guimarães, Hélio A. Duarte,
Chemical speciation of Mn(II) in aqueous solution has been investigated by means of density functional methods. Different geometries and electronic states of all species arising from the Mn(II) hydrolysis have been calculated. The Gibbs free energy of the hydrolysis reaction and the respective equilibrium constants have been estimated and compared with the available experimental data. Polarizable continuum model (PCM-UAHF/6-31+G(d)) was used to estimate the solvation energy. The ionization potential ...
Tópico(s): Electrochemical Analysis and Applications
2008 - Wiley | International Journal of Quantum Chemistry
Produção Nacional
Revisado por pares
Marina Luciana Abrêu de Melo, Leonardo Inforsato, Everton Alves Rodrigues Pinheiro, Quirijn de Jong van Lier,
Plant available water (PAW) is an important indicator of soil suitability for crop growth and biomass production. Total available water (TAW) is defined as the difference between the water content at field capacity (FC) and at wilting point (WP). The readily available water (RAW) is a fraction of TAW defined as the water content between FC and the limiting point (LP). The challenge in determining TAW and RAW lies in the correct determination of FC, WP, and LP. We propose a process-based approach to address ...
Tópico(s): Irrigation Practices and Water Management
2022 - Elsevier BV | Geoderma
Produção Nacional
Revisado por pares
Marina Luciana Abrêu de Melo, Quirijn de Jong van Lier,
The widely used Feddes reduction function (FRF) was reviewed in the context of its merits and shortcomings for modeling root water uptake (RWU), crop transpiration, and soil water balance components. The empirical nature of the FRF was contrasted to few calibrations reported in the literature, and the conditions where the correct operation of the FRF was of limited importance were discussed. Some alerts regarding the feasibility of this function in hydrological studies were provided and reinforced ...
Tópico(s): Soil and Unsaturated Flow
2021 - Elsevier BV | Journal of Hydrology
Produção Nacional
Revisado por pares
Isadora D’Ávila Tassinari, Mirella Kielek Galvan Andrade, Luciana Abreu da Rosa, Mariana Leivas Müller Hoff, Ricardo Ribeiro Nunes, Éverton Lopes Vogt, Rafael Bandeira Fabres, Eduardo Farias Sanches, Carlos Alexandre Netto, Ana Helena da Rosa Paz, Luciano Stürmer de Fraga,
Neonatal hypoxic–ischemic encephalopathy is a major cause of mortality and disability in newborns and the only standard approach for treating this condition is therapeutic hypothermia, which shows some limitations. Thus, putative neuroprotective agents have been tested in animal models. The present study evaluated the administration of lactate, a potential energy substrate of the central nervous system (CNS) in an animal model of hypoxia–ischemia (HI), that mimics in neonatal rats the brain damage ...
Tópico(s): Neuroscience of respiration and sleep
2020 - Elsevier BV | Neuroscience
Produção Nacional
Revisado por pares
Rafael Bandeira Fabres, Luciana Abreu da Rosa, Samir Khal de Souza, Ana Lúcia Cecconello, Amanda Stapenhorst Azambuja, Eduardo Farias Sanches, Maria Flávia Marques Ribeiro, Luciano Stürmer de Fraga,
Tópico(s): Immune Response and Inflammation
2018 - Springer Science+Business Media | Metabolic Brain Disease
Produção Nacional
Revisado por pares
Rejane C. Marques, Luciana Abreu, José Vicente Elias Bernardi, José G. Dórea,
Features of traditional living in the Amazon Basin (high fish consumption and long breastfeeding) are likely to expose children to Mercury (Hg).To study neurodevelopment in 690 children in relation to prolonged breastfeeding and mercury exposure.Three groups of breastfeeding children were formed: Group 1 (breastfed for 6 months), Group 2 (7-12 months) and Group 3 (extending up to 24 months). Neurodevelopment was assessed as age of walking, age of talking and the Bayley Scales of Infant Development-BSID. ...
Tópico(s): Child Nutrition and Water Access
2016 - Informa | Annals of Human Biology
Produção Nacional
Revisado por pares
Rejane C. Marques, Luciana Abreu, José Vicente Elias Bernardi, José G. Dórea,
Few studies have addressed co-occurring methylmercury (MeHg) from maternal origin and ethylmercury (EtHg) from Thimerosal-containing vaccines (TCVs) during infant's neurodevelopment. We studied children (n=1139) from the Western Amazon based on combined (low, intermediate, and high) exposure to chronic MeHg from fish consumption and acute TCV- EtHg. Neurodevelopment outcomes were age of walking and age of talking, and the Bayley Scale of Infant Development (BSID). The Mental Developmental Index (MDI) and ...
Tópico(s): Air Quality and Health Impacts
2016 - Elsevier BV | Environmental Research
Produção Nacional
Revisado por pares
Eric M. Garcia, Hosane Aparecida Tarôco, Rosana Zacarias Domingues, Túlio Matencio, Sicele Luciana Abreu Gonçalves,
Tópico(s): Advancements in Battery Materials
2016 - Springer Science+Business Media | Ionics
Produção Nacional
José G. Dórea, Rejane C. Marques, Luciana Abreu,
Neurological outcomes (Gesell development schedules [GDS]), age of walking, and age of talking were studied in 299 toddlers (12 to 24 mo) in relation to environmental (fish consumption and tin mining) exposure. Exposure to fish methylmercury (MeHg) consumption and iatrogenic ethylmercury (EtHg) in Thimerosal-containing vaccines (TCV) was quantified in toddlers from two rural villages (n = 91, Itapuã; n = 218, Bom Futuro) respectively populated by fishers and cassiterite miners. Median total hair Hg (HHg) concentrations ...
Tópico(s): Air Quality and Health Impacts
2014 - Taylor & Francis | Journal of Toxicology and Environmental Health
Produção Nacional
Revisado por pares
Rejane C. Marques, José Vicente Elias Bernardi, Luciana Abreu, José G. Dórea,
Tópico(s): Air Quality and Health Impacts
2014 - Springer Science+Business Media | Archives of Environmental Contamination and Toxicology
Produção Nacional
Revisado por pares
Kênia Maria Soares de Toubes, Maria Ilma de Souza Côrtes, Maria Alice de Abreu Valadares, Luciana Cardoso Fonseca, Eduardo Nunes, Frank Ferreira Silveira,
Introduction The objective of the present in vitro study was to compare 4 diagnostic methods to identify accessory mesial canals (AMCs) in lower first molars. Methods Forty-four lower first molars were selected for assessment with cone-beam computed tomography (CBCT), digital radiography (DR), clinical inspection (CI), and dental operating microscope (DOM). Initially, axial images were obtained by using CBCT, and radiographs were taken in ortho, mesial, and distal angulations. The images were assessed ...
Tópico(s): dental development and anomalies
2012 - Elsevier BV | Journal of Endodontics
Produção Nacional
Revisado por pares
Teresa Cristina Abreu Ferrari, Luciana Costa Faria, Tatiane S. Vilaça, Cristiane Rodrigues Corrêa, Alfredo M. Góes,
Abstract The pathogenesis of neuroschistosomiasis is largely unknown. Available evidence suggests that it depends on the presence of parasite eggs in the nervous tissue and on the host's immune response. We investigated the presence of immune complexes (ICs) in the cerebrospinal fluid (CSF) of four patients with spinal cord schistosomiasis (SCS), and performed their characterization. ICs containing soluble egg antigen of Schistosoma mansoni (SEA) were found in the CSF of all the SCS patients. To our knowledge, ...
Tópico(s): Parasitic infections in humans and animals
2010 - Elsevier BV | Journal of Neuroimmunology
Produção Nacional
Revisado por pares
Magna Cottini Fonseca Passos, Luana Cristina da Costa da Silva, Teresa Cristina Abreu Ferrari, Luciana Costa Faria,
A case of acute toxaemic schistosomiasis is presented. Abdominal ultrasound examination revealed hepatosplenomegaly, lymphadenomegaly, heterogeneous hepatic parenchyma and heterogeneous focal lesions in the pancreas. CT confirmed lymph node enlargement and hepatosplenomegaly, and showed multiple small focal nodular lesions in the liver and focal lesions in the pancreas. To our knowledge, this is the first description of pancreatic lesions associated with acute Schistosoma mansoni infection.
Tópico(s): Parasite Biology and Host Interactions
2009 - Wiley | British Journal of Radiology
Produção Nacional
Revisado por pares
Victor Meriguetti Pinto, André Fróes de Borja Reis, Marina Luciana Abrêu de Melo, Klaus Reichardt, Deivison Santos, Quirijn de Jong van Lier,
Drought events and water use conflicts drive the need for more efficient water management in rice-growing areas of the Brazilian Cerrado. Recent studies have shown the advantages of adopting water-saving irrigation in the region but a comprehensive assessment is needed. This study aims to model the performance of rice cultivation and water productivity in the tropical floodplains of the Cerrado biome of northern Brazil in response to irrigation management under contrasting seasonal rainfall levels. ...
Tópico(s): Plant responses to water stress
2023 - Elsevier BV | Agricultural Water Management
Produção Nacional
Revisado por pares
Marcos Eli Buzanskas, Ricardo Vieira Ventura, T.C.S. Chud, Priscila Arrigucci Bernardes, Daniel Jordan de Abreu Santos, Luciana Correia de Almeida Regitano, M. M. de Alencar, Maurício A. Mudadu, Ricardo Zanella, Marcos Vinícius Gualberto Barbosa da Silva, Changxi Li, Flávio S. Schenkel, Danísio Prado Munari,
The aim of this study was to evaluate the level of introgression of breeds in the Canchim (CA: 62.5% Charolais-37.5% Zebu) and MA genetic group (MA: 65.6% Charolais-34.4% Zebu) cattle using genomic information on Charolais (CH), Nelore (NE), and Indubrasil (IB) breeds. The number of animals used was 395 (CA and MA), 763 (NE), 338 (CH), and 37 (IB). The Bovine50SNP BeadChip from Illumina panel was used to estimate the levels of introgression of breeds considering the Maximum likelihood, Bayesian, and Single ...
Tópico(s): Genetic diversity and population structure
2017 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Jahina Moura Vidal, Angela Mendes Abreu, Luciana Fernandes Portela,
Resumo: Os objetivos foram avaliar a associação entre o estresse psicossocial no trabalho e o padrão de consumo de álcool em trabalhadores offshore. Trata-se de um estudo transversal realizado com 210 prestadores de serviço em instalações petrolíferas situadas no Estado do Rio de Janeiro, Brasil, entre julho e setembro de 2014. O instrumento de coleta consistiu em um questionário multidimensional autopreenchido. A exposição ao estresse foi avaliada segundo o modelo demanda-controle e o padrão de ...
Tópico(s): Employment and Welfare Studies
2017 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Produção Nacional
Revisado por pares
Andrés Maurício Rico Gómez, Quirijn de Jong van Lier, Nélida Elizabet Quiñonez Silvero, Leonardo Inforsato, Marina Luciana Abrêu de Melo, Heidy Soledad Rodríguez Albarracín, Nícolas Augusto Rosin, Jorge Tadeu Fim Rosas, Rodnei Rizzo, José Alexandre Melo Demattê,
Soil available water capacity (AWC) is a key function for human survival and well-being. However, its direct measurement is laborious and spatial interpretation is complex. Digital soil mapping (DSM) techniques emerge as an alternative to spatial modeling of soil properties. DSM techniques commonly apply machine learning (ML) models, with a high level of complexity. In this context, we aimed to perform a digital mapping of soil AWC and interpret the results of the Random Forest (RF) algorithm and, in ...
Tópico(s): Soil and Unsaturated Flow
2023 - Elsevier BV | The Science of The Total Environment
Produção Nacional
Revisado por pares
Luciana de Abreu Silva, Bárbara Júlia Fonseca Verneque, Ana Paula Lucas Mota, Camila Kümmel Duarte,
Chia ( Salvia hispanica L.) is an annual herbaceous plant, originally from southern Mexico and northern Guatemala – nowadays grown all over the world.
Tópico(s): Hibiscus Plant Research Studies
2021 - Royal Society of Chemistry | Food & Function
Produção Nacional
Revisado por pares
Bárbara Júlia Fonseca Verneque, Adriane Moreira Machado, Luciana de Abreu Silva, Aline Cristine Souza Lopes, Camila Kümmel Duarte,
The development of cardiometabolic diseases is related to conditions such as obesity, abdominal fat, insulin resistance, diabetes mellitus, elevated blood pressure and changes in lipid profile. The whole of Trans Fatty Acid (TFA) intake is associated with the increase of cardiometabolic risk factors. There are two main sources of TFA, the ruminant TFA (rTFA) which are produced by biohydrogenation in animal's rumen, and the industrial TFA (iTFA), produced by hydrogenation of vegetable oils, the individual ...
Tópico(s): Obesity, Physical Activity, Diet
2020 - Taylor & Francis | Critical Reviews in Food Science and Nutrition
Produção Nacional
Revisado por pares
Andrew Dauber, Marina Cunha-Silva, Delanie B. Macedo, Vinícius Nahime Brito, Ana Paula Abreu, Stephanie Roberts, Luciana Ribeiro Montenegro, Melissa Andrew, Andrew Kirby, Matthew T. Weirauch, Guillaume Labilloy, Danielle S. Bessa, Rona S. Carroll, Dakota C. Jacobs, Patrick E. Chappell, Berenice B. Mendonça, David Haig, Ursula B. Kaiser, Ana Claudia Latrônico,
Abstract Context: Central precocious puberty (CPP) results from premature activation of the hypothalamic–pituitary–gonadal axis. Few genetic causes of CPP have been identified, with the most common being mutations in the paternally expressed imprinted gene MKRN3. Objective: To identify the genetic etiology of CPP in a large multigenerational family. Design: Linkage analysis followed by whole-genome sequencing was performed in a family with five female members with nonsyndromic CPP. Detailed phenotyping ...
Tópico(s): Genomics and Chromatin Dynamics
2017 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Produção Nacional
Revisado por pares
Giselly Silva Neto de Crignis, Luciana de Abreu, Alice Mota Buçard, Carlos Baptista Barcauí,
Mammary Paget's disease is a rare intraepithelial adenocarcinoma, located on the nipple/areola complex, highly associated with breast cancer. Although the international literature emphasizes the dermatoscopic pattern of mammary Paget's disease pigmented variant, the authors describe the dermoscopic findings of classical Paget's disease and demonstrate the presence of chrysalis-like structures, criteria recently described in the literature and not yet reported in Paget's disease.
Tópico(s): Breast Lesions and Carcinomas
2013 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
Robertha Carvalho de Nakamura, Luciana de Abreu, Bruna Duque‐Estrada, Carla Tamler, Andréia Leverone,
BACKGROUND: Nail psoriasis may affect up to 90% of patients with psoriasis in the course of the disease throughout their lives and it is often a therapeutic challenge to dermatologists. Topical treatments described in the literature have demonstrated variable efficacy, and unsatisfactory results have been associated to inefficient penetration of the active ingredient into the nail plate and proximal nail fold. Recently the use of clobetasol on nail lacquer vehicle has been suggested, with satisfactory ...
Tópico(s): Cutaneous lymphoproliferative disorders research
2012 - Elsevier BV | Anais Brasileiros de Dermatologia
Mónica Válega, S. N. Abreu, Pedro Pato, Luciana S. Rocha, Ana R. Gomes, Eduarda Pereira, Armando C. Duarte,
Tópico(s): Heavy metals in environment
2006 - Springer Science+Business Media | Water Air & Soil Pollution