Produção Nacional
Revisado por pares
Pedro Vianna Gatts, Marcos Alberto Lima Franco, Luciano Neves dos Santos, Diogo Fonseca da Rocha, Ilana Rosental Zalmon,
To investigate how variations in the volume of artificial reefs affect the structure and composition of the transient ichthyofauna, reefball-type concrete modules were arranged at 9 m of depth along the northern coast of the state of Rio de Janeiro. The modules were arranged in three configurations, each in triplicate: (1) solitary modules (1 m3), (2) side-by-side modules (2 m3) and (3) modules forming a triangle (3 m3). The surrounding ichthyofauna were sampled in two periods of the year (dry: September ...
Tópico(s): Coral and Marine Ecosystems Studies
2014 - Elsevier BV | Ocean & Coastal Management
Thiago Nunes Pereira, Fabiano Duarte Carvalho, Silvana F. de Mendonça, Marcele Neves Rocha, Luciano Andrade Moreira,
Newly emerging or re-emerging arthropod-borne viruses (arboviruses) are important causes of human morbidity and mortality worldwide. Arboviruses such as Dengue (DENV), Zika (ZIKV), Chikungunya (CHIKV), and West Nile virus (WNV) have undergone extensive geographic expansion in the tropical and sub-tropical regions of the world. In the Americas the main vectors of DENV, ZIKV, and CHIKV are mosquito species adapted to urban environments, namely Aedes aegypti and Aedes albopictus, whereas the main vector ...
Tópico(s): Insect symbiosis and bacterial influences
2020 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Lívia Baldon, Silvana F. de Mendonça, Flávia V. Ferreira, Fernanda Oliveira Rezende, Siad C. G. Amadou, Thiago H. J. F. Leite, Marcele Neves Rocha, João T. Marques, Luciano Andrade Moreira, Álvaro Ferreira,
Arboviruses (an acronym for “arthropod-borne virus”), such as dengue, yellow fever, Zika, and Chikungunya, are important human pathogens transmitted by mosquitoes. These viruses impose a growing burden on public health. Despite laboratory mice having been used for decades for understanding the basic biological phenomena of these viruses, it was only recently that researchers started to develop immunocompromised animals to study the pathogenesis of arboviruses and their transmission in a way that parallels ...
Tópico(s): Malaria Research and Control
2022 - Multidisciplinary Digital Publishing Institute | Pathogens
Produção Nacional
Revisado por pares
Pedro Vianna Gatts, Marcos Alberto Lima Franco, Luciano Neves dos Santos, Diogo Fonseca da Rocha, Fabrício de Sá, Eurico Netto, Phillipe Mota Machado, Bruno Pereira Masi, Ilana Rosental Zalmon,
Tópico(s): Fish biology, ecology, and behavior
2015 - Springer Science+Business Media | Aquatic Ecology
Produção Nacional
Revisado por pares
Daniela da Silva Gonçalves, Iñaki Iturbe‐Ormaetxe, Andrea Martins-da-Silva, Erich Loza Telleria, Marcele Neves Rocha, Yara Maria Traub-Csekö, Scott L. O’Neill, Maurício Roberto Viana Sant’Anna, Luciano Andrade Moreira,
The leishmaniases are important neglected diseases caused by Leishmania spp. which are transmitted by sand flies, Lutzomyia longipalpis being the main vector of visceral leishmaniasis in the Americas. The methodologies for leishmaniasis control are not efficient, causing 1.5 million reported cases annually worldwide, therefore showing the need for development of novel strategies and interventions to control transmission of the disease. The bacterium Wolbachia pipientis is being used to control viruses ...
Tópico(s): Research on Leishmaniasis Studies
2019 - BioMed Central | Parasites & Vectors
Produção Nacional
Revisado por pares
Rafael Lacerda Macêdo, Philip Russo, Raphael Ferreira Corrêa, Odete Rocha, Luciano Neves dos Santos, Christina Wyss Castelo Branco,
Tópico(s): Marine and coastal ecosystems
2021 - Springer Science+Business Media | Hydrobiologia
Produção Nacional
Revisado por pares
Thiago Nunes Pereira, Marcele Neves Rocha, Pedro Henrique Ferreira Sucupira, Fabiano Duarte Carvalho, Luciano Andrade Moreira,
Wolbachia, an intracellular endosymbiont present in up to 70% of all insect species, has been suggested as a sustainable strategy for the control of arboviruses such as Dengue, Zika and Chikungunya. As Mayaro virus outbreaks have also been reported in Latin American countries, the objective of this study was to evaluate the vector competence of Brazilian field-collected Ae. aegypti and the impact of Wolbachia (wMel strain) upon this virus. Our in vitro studies with Aag2 cells showed that Mayaro virus ...
Tópico(s): Mosquito-borne diseases and control
2018 - Nature Portfolio | Scientific Reports
Guilherme Garcia Pinheiro, Marcele Neves Rocha, Maria Angélica de Oliveira, Luciano Andrade Moreira, José Dilermando Andrade Filho,
Brazil has experienced several arbovirus outbreaks in recent years, among which yellow fever stands out. The state of Minas Gerais faced outbreaks of sylvatic yellow fever in 2017 and 2018, with 1002 confirmed cases and 340 deaths. This work presents the results of survey efforts to detect the yellow fever virus in mosquitoes from two conservation areas in the metropolitan region of Belo Horizonte, Brazil. A total of 867 mosquitoes of 20 species were collected between September 2017 and May 2018, ...
Tópico(s): Insect and Pesticide Research
2019 - Multidisciplinary Digital Publishing Institute | Insects
Eric P. Caragata, Marcele Neves Rocha, Thiago Nunes Pereira, Simone Brutman Mansur, Heverton Leandro Carneiro Dutra, Luciano Andrade Moreira,
Background Wolbachia's ability to restrict arbovirus transmission makes it a promising tool to combat mosquito-transmitted diseases. Wolbachia-infected Aedes aegypti are currently being released in locations such as Brazil, which regularly experience concurrent outbreaks of different arboviruses. A. aegypti can become co-infected with, and transmit multiple arboviruses with one bite, which can complicate patient diagnosis and treatment. Methodology/principle findings Using experimental oral infection ...
Tópico(s): Insect and Pesticide Research
2019 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Heverton Leandro Carneiro Dutra, Marcele Neves Rocha, Fernando Braga Stehling Dias, Simone Brutman Mansur, Eric P. Caragata, Luciano Andrade Moreira,
The recent association of Zika virus with cases of microcephaly has sparked a global health crisis and highlighted the need for mechanisms to combat the Zika vector, Aedes aegypti mosquitoes. Wolbachia pipientis, a bacterial endosymbiont of insect, has recently garnered attention as a mechanism for arbovirus control. Here we report that Aedes aegypti harboring Wolbachia are highly resistant to infection with two currently circulating Zika virus isolates from the recent Brazilian epidemic. Wolbachia- ...
Tópico(s): Insect and Pesticide Research
2016 - Cell Press | Cell Host & Microbe
Produção Nacional
Revisado por pares
Rafael Luciano Dalcin, Alexandre da Silva Rocha, Victor Velho de Castro, Julio Cesar Klein das Neves, Carlos Henrique da Silva, Ricardo Torres, Rafael Menezes Nunes, Célia de Fraga Malfatti,
For the first time, the influence of gas mixture on first damage resistance of a plasma nitrided DIN 18MnCrSiMo6-4 bainitic steel was investigated. Samples were nitrided at 500 °C with three different N2-H2 gas mixtures, containing 5, 24, and 76 vol.% N2. Samples were characterized concerning the resulting roughness, microstructure, compound layer's phase composition, residual stresses in the diffusion zone, and surface hardness. Tribological ball-on-flat tests were carried out in reciprocal mode ...
Tópico(s): Diamond and Carbon-based Materials Research
2021 - Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímer | Materials Research
Produção Nacional
Revisado por pares
Gaspar Henrique Korndörfer, Hamilton Seron Pereira, Ivaniele Nahas Duarte, Laerte Rocha Neves Pinto, Luciano Ferreira da Fonseca,
Thermopotash is a fertilizer with low solubility but has a release level compatible with plant demands. This study aimed to compare the effect of Thermopotash to that of KCl in sugarcane. Field work was conducted during two crop seasons, in a randomised block design. Treatments were applied to the bases of the furrows before planting the sugarcane, arranged in a 2 x 5 factorial design to evaluate two K sources (TK47 - Thermopotash, KCl - potassium chloride) at five levels of K (0, 50, 100, 150, and 200 ...
Tópico(s): Soil Management and Crop Yield
2018 - Editora da Universidade Estadual de Maringá (Eduem) | Acta Scientiarum Agronomy
Produção Nacional
Revisado por pares
João Silveira Moledo Gesto, Gabriel Sylvestre Ribeiro, Marcele Neves Rocha, Fernando Braga Stehling Dias, Julia Peixoto, Fabiano Duarte Carvalho, Thiago Nunes Pereira, Luciano Andrade Moreira,
Abstract Field release of Wolbachia -infected Aedes aegypti has emerged as a promising solution to manage the transmission of dengue, Zika and chikungunya in endemic areas across the globe. Through an efficient self-dispersing mechanism, and the ability to induce virus-blocking properties, Wolbachia offers an unmatched potential to gradually modify wild Ae. aegypti populations turning them unsuitable disease vectors. Here we describe a proof-of-concept field trial carried out in a small community ...
Tópico(s): Insect and Pesticide Research
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Antônia Leila Rocha Neves, Claudivan Feitosa de Lacerda, Carlos Henrique Carvalho de Sousa, Francisco Leandro Barbosa da Silva, Hans Raj Gheyi, F.J. Ferreira, Francisco Luciano Andrade Filho,
This study aimed to evaluate the effect of management strategies of irrigation with saline water on growth and yield of cowpea and sunflower in a crop rotation. The experiment was conducted in randomized blocks with thirteen treatments and five replications. The treatments consisted of: T1 (control), T2, T3 and T4 using water of 0.5 (A1), 2.2 (A2), 3.6 (A3) and 5.0 (A4) dS m-1, respectively, during the entire crop cycle; T5, T6 and T7, use of A2, A3 and A4 water, respectively, only in the flowering and ...
Tópico(s): Plant Micronutrient Interactions and Effects
2015 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
Produção Nacional
Revisado por pares
Itamar Luís Gonçalves, Liliana Rockenbach, Gustavo Machado das Neves, Gabriela Göethel, Fabiana Nascimento, Luciano Porto Kagami, Fabrício Figueiró, Gabriel Oliveira de Azambuja, Amanda de Fraga Dias, A Benitez Amaro, Lauro Mera de Souza, Ivan da Rocha Pitta, Daiana Silva Ávila, Daniel Fábio Kawano, Solange Cristina García, Ana Maria Oliveira Battastini, Vera Lucia Eifler‐Lima,
An original and focused library of two sets of dihydropyrimidin-2-thiones (DHPMs) substituted with N-1 aryl groups derived from monastrol was designed and synthesized in order to discover a more effective Eg5 ligand than the template. Based on molecular docking studies, four ligands were selected to perform pharmacological investigations against two glioma cell lines. The results led to the discovery of two original compounds, called
Tópico(s): Advanced Fluorescence Microscopy Techniques
2018 - Royal Society of Chemistry | MedChemComm
Produção Nacional
Revisado por pares
Silvana F. de Mendonça, Marcele Neves Rocha, Flávia V. Ferreira, Thiago H. J. F. Leite, Siad C. G. Amadou, Pedro Henrique Ferreira Sucupira, João T. Marques, Álvaro Ferreira, Luciano Andrade Moreira,
The emergence of new human viral pathogens and re-emergence of several diseases are of particular concern in the last decades. Oropouche orthobunyavirus (OROV) is an arbovirus endemic to South and Central America tropical regions, responsible to several epidemic events in the last decades. There is little information regarding the ability of OROV to be transmitted by urban/peri-urban mosquitoes, which has limited the predictability of the emergence of permanent urban transmission cycles. Here, we ...
Tópico(s): Vector-Borne Animal Diseases
2021 - Multidisciplinary Digital Publishing Institute | Viruses
Produção Nacional
Revisado por pares
Rafael Luciano Dalcin, Valcir Marques de Menezes, Leonardo Fonseca Oliveira, Carlos Henrique da Silva, Julio Cesar Klein das Neves, Carla Adriana Theis Soares Diehl, Alexandre da Silva Rocha,
In the present investigation, the use of a bainitic steel for forged gears applications and the suitability of different plasma nitriding treatments is discussed. The gears were forged, machined, ground, polished, and nitrided at 500 °C with three sets of N2–H2 gas mixtures, containing 5, 24, and 76 vol.% N2, to develop a nitrided case of approximately 300 μm depth. Gears were characterized before and after the nitriding concerning the phase composition, microstructure, microhardness, fracture toughness, ...
Tópico(s): Diamond and Carbon-based Materials Research
2022 - Elsevier BV | Journal of Materials Research and Technology
Produção Nacional
Revisado por pares
Rafael Luciano Dalcin, Alexandre da Silva Rocha, Victor Velho de Castro, Leonardo Fonseca Oliveira, Julio Cesar Klein das Neves, Carlos Henrique da Silva, Célia de Fraga Malfatti,
In this study, the sliding wear of a DIN 18MnCrSiMo6-4 continuous cooling bainitic steel plasma nitrided with a nitrogen rich gas composition was investigated. To evaluate the influence of processing time and temperature on mechanical and microstructural characteristics of nitrided layer, the samples were nitrided at 400, 450, 500 and 550 °C for 3, 6 and 9 h. The produced nitrided layers were characterized concerning the microstructure, phase composition, microhardness and surface roughness. The ...
Tópico(s): Diamond and Carbon-based Materials Research
2021 - Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímer | Materials Research
Produção Nacional
Revisado por pares
Roenick Proveti Olmo, Álvaro Ferreira, Tatiane C. Izidoro‐Toledo, Eric Roberto Guimarães Rocha Aguiar, Isaque J. S. de Faria, Kátia Paulino Ribeiro de Souza, Kátia P. Osório, Lauriane Kühn, Philippe Hammann, Elisa G. de Andrade, Yaovi Mathias Honore Todjro, Marcele Neves Rocha, Thiago H. J. F. Leite, Siad C. G. Amadou, Juliana N. Armache, Simona Paro, Caroline Dantas de Oliveira, Fabiano Duarte Carvalho, Luciano Andrade Moreira, Eric Marois, Jean‐Luc Imler, João T. Marques,
Dengue virus (DENV) is an arbovirus transmitted to humans by Aedes mosquitoes1. In the insect vector, the small interfering RNA (siRNA) pathway is an important antiviral mechanism against DENV2–5. However, it remains unclear when and where the siRNA pathway acts during the virus cycle. Here, we show that the siRNA pathway fails to efficiently silence DENV in the midgut of Aedes aegypti although it is essential to restrict systemic replication. Accumulation of DENV-derived siRNAs in the midgut reveals ...
Tópico(s): Insect symbiosis and bacterial influences
2018 - Nature Portfolio | Nature Microbiology
Produção Nacional
Revisado por pares
Jacqueline Araújo Domingos Iturra, Leonardo Maia Leony, Fernanda Alvarenga Cardoso Medeiros, Job Alves de Souza Filho, Liliane da Rocha Siriano, Suelene Brito do Nascimento Tavares, Alejandro O. Luquetti, Vinícius Silva Belo, Andréa Silvestre de Sousa, Fred Luciano Neves Santos,
Diagnosis of Trypanosoma cruzi ( T. cruzi ) infection in the chronic phase of Chagas disease (CD) is performed by serologic testing. Conventional tests are currently used with very good results but require time, laboratory infrastructure, and expertise. Rapid diagnostic tests (RDTs) are an alternative as the results are immediate and do not require specialized knowledge, making them suitable for epidemiologic studies and promising as a screening tool. Nevertheless, few studies conducted comparative evaluations ...
Tópico(s): Insect symbiosis and bacterial influences
2023 - Frontiers Media | Frontiers in Medicine
Produção Nacional
Thaliane França Costa, Ana Vitória Verde Oliveira Rocha, Leandro Macêdo Miranda, Larissa Fernanda Soares Lima, Fred Luciano Neves Santos, Ângelo Antônio Oliveira Silva, Fernando Almeida-Souza, Anaiá da Paixão Sevá, Aline Diniz Cabral, Márcia Aparecida Sperança, Francisco Borges Costa, Rita de Maria Seabra Nogueira, Andréa Pereira da Costa,
Trypanosoma cruzi, the etiological agent for Chagas disease, is widely distributed in the Americas. Its hosts are humans and wild and domestic mammals, and its vectors are triatomine insects. Studies have indicated that domestic dogs are sentinel animals in the epidemiology of Chagas disease in endemic regions, including states in the Legal Amazon region of Brazil. In São Luís, the capital of Maranhão, a non-endemic state, the existence of a domestic cycle involving domestic rats has been proven, ...
Tópico(s): Parasitic Infections and Diagnostics
2021 - Elsevier BV | Veterinary Parasitology Regional Studies and Reports
Produção Nacional
Revisado por pares
Juan Carlos Yugar‐Toledo, Heitor Moreno, Miguel Gus, Guido Bernardo Aranha Rosito, Luiz César Nazário Scala, Elizabeth Silaid Muxfeldt, Alexandre Alessi, Andréa Araújo Brandão, Osni Moreira Filho, Audes D. M. Feitosa, O Passarelli Júnior, Dilma do Socorro Moraes de Souza, Celso Amodeo, Weimar Kunz Sebba Barroso, Marco Antônio Mota Gomes, Annelise Machado Gomes de Paiva, Eduardo Costa Duarte Barbosa, Roberto Dischinger Miranda, José Fernando Vilela-Martin, Wilson Nadruz, Cibele Isaac Saad Rodrigues, Luciano F. Drager, Luiz Aparecido Bortolotto, Fernanda Marciano Consolim‐Colombo, Márcio Gonçalves de Sousa, Flávio Borelli, Sérgio Kaiser, Gil F. Salles, Maria de Fátima de Azevedo, Lucélia Batista Neves Cunha Magalhães, Rui Póvoa, Marcus Vinícius Bolívar Malachias, Armando da Rocha Nogueira, Paulo César Brandão Veiga Jardim, Thiago Veiga Jardim,
1. Definicao e Epidemiologia Coordenador: Heitor Moreno Junior. Autores: Juan Carlos Yugar-Toledo, Heitor Moreno Junior, Miguel Gus, Guido Bernardo Aranha Rosito e Luiz Cesar Nazario Scala. […] Posicionamento Brasileiro sobre Hipertensao Arterial Resistente – 2020
Tópico(s): Sodium Intake and Health
2020 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Fernanda de Assis Araújo, M.A. Rocha, Luciano dos Santos Aggum Capettini, Paula Peixoto Campos, Mônica Alves Neves Diniz Ferreira, Virgı́nia S. Lemos, Sílvia Passos Andrade,
Statins, 3‐hydroxy‐3‐methylglutaryl coenzyme A ( HMG ‐ CoA ) reductase inhibitors, have been shown to ameliorate a number of vascular diseases. We evaluated the inflammatory and angiogenic components of the fibrovascular tissue induced by subcutaneous implants in mice and their modulation by fluvastatin. Our results showed that the statin (0.6 and 6 mg/kg/day) inhibited hemoglobin (Hb) content (51%) and vascular endothelial growth factor ( VEGF ) levels (71%) in the treated group compared with the control group. ...
Tópico(s): Inflammatory mediators and NSAID effects
2012 - Wiley | Apmis
Produção Nacional
Revisado por pares
Leôncio Lopes Soares, Luciano Bernardes Leite, Luiz Otávio Guimarães Ervilha, Bruno Rocha de Avila Pelozin, Noemy Pinto Pereira, Bruna Aparecida Fonseca da Silva, Alexandre Martins Oliveira Portes, Filipe Rios Drummond, Leonardo Mateus Teixeira de Rezende, Tiago Fernandes, Edilamar Menezes de Oliveira, Mariana Machado‐Neves, Emily Correna Carlo Reis, Antônio José Natali,
We tested the effects of low- to moderate-intensity resistance exercise training (RT) on the structure and function of pulmonary, right ventricle (RV), and skeletal muscle tissues in rats with stable pulmonary artery hypertension (PAH).After the first monocrotaline (MCT; 20 mg/kg) injection, male rats were submitted to a RT program (Ladder climbing; 55-65 % intensity), 5 times/week. Seven days later rats received the second MCT dose. Physical effort tolerance test and echocardiographic examination were ...
Tópico(s): Cardiovascular Effects of Exercise
2023 - Elsevier BV | Life Sciences
Produção Nacional
Revisado por pares
Amanda Cupertino de Freitas, Fernanda Rezende, Silvana de Mendonça, Lívia Baldon, Emanuel Silva, Flávia V. Ferreira, João Paulo P. de Almeida, Siad C. G. Amadou, Bruno Marçal, Sara Comini, Marcele Neves Rocha, Hegger Fritsch, Ellen Santos, Thiago H. J. F. Leite, Marta Giovanetti, Luíz Carlos Júnior Alcântara, Luciano Andrade Moreira, Álvaro Ferreira,
The incidence of chikungunya has dramatically surged worldwide in recent decades, imposing an expanding burden on public health. In recent years, South America, particularly Brazil, has experienced outbreaks that have ravaged populations following the rapid dissemination of the chikungunya virus (CHIKV), which was first detected in 2014. The primary vector for CHIKV transmission is the urban mosquito species Aedes aegypti, which is highly prevalent throughout Brazil. However, the impact of the locally ...
Tópico(s): Viral Infections and Vectors
2024 - Multidisciplinary Digital Publishing Institute | Viruses
Produção Nacional
Jaqueline Correa das Neves, Marlova Neumann Araujo, Luciano Daudt da Rocha,
As escolas cívico-militares são instituições não militarizadas, mas que contam com uma equipe militar atuando na função de tutores. Em 2019 foram anunciadas algumas escolas adotantes deste formato de ensino, trazendo assim, a necessidade de se buscar compreender os efeitos e as possibilidades que envolvem este modelo. Dentro deste contexto esse material apresentou a seguinte questão norteadora: o que a literatura ressalta em relação ao processo de militarização das escolas públicas brasileiras? ...
Tópico(s): Education during COVID-19 pandemic
2022 - | Revista Científica Multidisciplinar Núcleo do Conhecimento
Produção Nacional
Revisado por pares
Micaele Niobe Martins Cardoso, Fernanda Correia Azevedo, Alan Dias, ANA C.S. ALMEIDA, André R. Senna, Antônio Carlos Marques, Dafinny Rezende, Eduardo Hajdu, Erick Alves Pereira Lopes‐Filho, Fábio Bettini Pitombo, Gabriela Moura de Oliveira, João Gabriel Doria, João Luís Carraro, Joel Campos De‐Paula, Juliana Bahia, Juliana Magalhães de Araújo, Karla Paresque, Leandro M. Vieira, Luanny Martins Fernandes, Luciano Neves dos Santos, Lucília S. Miranda, Maria Lúcia Lorini, Michelle Klautau, Paulo Roberto Pagliosa, Pedro Henrique Braga Clerier, Rafael Bendayan de Moura, Rafael Fortes, Raquel A. F. Neves, Rosana Moreira da Rocha, Sérgio N. Stampar, Sula Salaní, Thaís Pires Miranda, Ulisses dos Santos Pinheiro, Virág Venekey, Ubirajara Oliveira,
Abstract Aim Knowledge gaps and sampling bias can lead to underestimations of species richness and distortions in the known distribution of species. The goal of this study is to identify potential gaps and biases in marine organisms sampling at the Western Atlantic Ocean, determine their causes and assess its effect on biodiversity metrics. We tested the potential interference of this bias with the representation of environmental conditions, potentially affecting biodiversity model predictions. ...
Tópico(s): Wildlife Ecology and Conservation
2024 - Wiley | Diversity and Distributions
Lucas Resende Dutra Sousa, Maria L. S. Azevedo, Dayana Rocha, Ângela Leão Andrade, Tatiane Roquete Amparo, Orlando David Henrique dos Santos, Janaína Brandão Seibert, Luciano Pereira, Paula Melo de Abreu Vieira, Cláudia Martins Carneiro, Ana Paula M. Barboza, Bernardo R. A. Neves, Policarpo Ademar Sales, Silvane Maria Fonseca Murta, Kátia Monteiro Novack, Viviane Martins Rebello dos Santos,
Selecting a polymer depends on its characteristics, the properties of the drug and of the remaining ingredients in the formulation. The drug, when incorporated into a polymeric matrix, can show several advantages when compared with its conventional form. In this context, this work describes the preparation and characterization of polyethylene glycol (PEG 4000) and its derivative particles loaded with benznidazole, as well as evaluates their trypanocidal activity. In this work, reactions to modify ...
Tópico(s): Viral Infections and Immunology Research
2021 - Brazilian Chemical Society | Journal of the Brazilian Chemical Society
Produção Nacional
Revisado por pares
Laryssa Santos Metzker, Luyanne Azevedo Cabral Ferreira, Julia Caroliny Nogueira Borges, Mariana Furieri Guzzo, Rodrigo Neves Ferreira, Lucas Luciano Rocha Silva, Rodrigo Monico Cavedo, Antônio Chambô Filho,
Ovarian hyperthecosis or ovarian stromal hyperplasia is a non-neoplastic functional disorder resulting from the presence of luteinized thecal cells within a hyperplastic ovarian stroma. The condition is more common in postmenopausal women than in those of reproductive age and leads to substantial clinical and laboratory alterations, principally androgenetic alopecia, progressive hirsutism, and elevated testosterone levels. Investigation should include clinical evaluation, laboratory tests, and imaging ...
Tópico(s): Endometriosis Research and Treatment
2023 - Hindawi Publishing Corporation | Case Reports in Obstetrics and Gynecology
Produção Nacional
Revisado por pares
Ubirajara Oliveira, Fernanda Correia Azevedo, Alan Dias, ANA C.S. ALMEIDA, André R. Senna, Antônio Carlos Marques, Dafinny Rezende, Eduardo Hajdu, Erick Alves Pereira Lopes‐Filho, Fábio Bettini Pitombo, Gabriela Moura de Oliveira, João Gabriel Doria, João Luís Carraro, Joel Campos De‐Paula, Juliana Bahia, Juliana Magalhães de Araújo, Karla Paresque, Leandro M. Vieira, Luanny Martins Fernandes, Micaele Niobe Martins Cardoso, Luciano Neves dos Santos, Lucília S. Miranda, Michelle Klautau, Paulo Roberto Pagliosa, Pedro Henrique Braga Clerier, Rafael Bendayan de Moura, Rafael Fortes, Raquel A. F. Neves, Rosana Moreira da Rocha, Sérgio N. Stampar, Sula Salaní, Thaís Pires Miranda, Ulisses dos Santos Pinheiro, Virág Venekey,
Abstract Aim Understanding the factors determining marine community variations is important for biogeography and conservation. Beta diversity is a metric for mapping species composition variations between communities and regionalizing biota. Ecoregions are commonly used for regionalization, but their empirical testing has been limited. Our aim is to map marine species composition variations in the Western Atlantic, identify variables related to these variations, and regionalize areas based on community ...
Tópico(s): Coral and Marine Ecosystems Studies
2024 - Wiley | Journal of Biogeography