Frances Gibb, Legal Affairs Correspondent, H. P. Rowe, Chris Petit, Robert D. Williams, Catherine Bennett, Patricia Davies, Gordon Allan, Harvey Elliott, B. L. áB. Robinson, Cliff Feltham, Ivo Tennant, Hilary Finch, John Pinnock, John Douglas, Michael Binyon, Jeremy Kingston, John M. Goldman, , Carol Leonard, Richard Streeton, Stuart Jones Football Correspondent, J. K., Michael McCarthy, Joe Joseph, Ruth Gledhill, David Housham, Pearce Wright Science Editor, Rodney Cowton, Transport Correspondent, Mick Cleary, Michael Evans, Defence Correspondent, Christopher Price, Ray Kennedy, Martin Cropper, Robin Young, Wesley Gryk, Edward Bach, C. H. Lawrence, Thomson Prentice, Science Correspondent, Michael Clark, Graham Corneck, Charles Elliott, Peter Miller, Richard Thomson, Banking Correspondent, John Hennessy, David Galton, , Gavin Bell, Daniel Catovsky, Ronald Fletcher, Harry Debelius, Sydney Friskin, David Miller, Philip Webster, Chief Political Correspondent, Geoffrey Wheeler, (Michael Phillips), Josephine Fairley, Alan Toogood, Horticulture Correspondent, Dominic Vlasto, A. D. C. Turner (Director), Barry Wood Los Angeles, Rodney Cowton Transport Correspondent, Peter Dear and Jane Rackham, John A. Hill, Alexandra Jackson, Peter Bryan, Stewart Tendler Crime Reporter, Robert Matthews, PHS, Martin Searby, Barry Pickthall, Roger Boyes, Russell Hoban's, David Sapsted, Derek Harris, Industrial Editor, Kenneth Fleet, Christopher Warman Property Correspondent, Christopher Thomas, Thomas Land, Ian Smith, Jill Hows, , Helen Franks, Jill Sherman Social Services Correspondent, Carol Ferguson, Edward Townsend, Industrial Correspondent, Clive White, Robert Grieves, Alan Lee, Stephen Pettitt, Lucio Luzzatto, , Howard Jacobson, Michael Horsnell, John Spicer Employment Affairs Correspondent, Sarah Thompson, Alan McGregor, John Woodcock, Cricket Correspondent, Robert Fisk, Paul Fox, Richard Morrison, Jack Bailey, Keith Macklin, Susan MacDonald, Colin Campbell, Mac Margolis, Nick Higham, Philip Jacobson, Michael Coleman, Colin McQuillan, Rodney Lord Economics Editor, Ray Heath,
Britain orders minesweepers into the Gulf Change of heart 'to ensure safety of innocent neutral shipping' France to reinforce task fleet PO chairman Exam ...
1987 - Gale Group | TDA
Rui Luzzatto, Gustavo Sisson, Lucio Luzzatto, Marta Recktenvald, Newton Brücker,
... author on: This Site PubMed Google Scholar Lucio Luzzatto; Lucio Luzzatto From the Instituto de Patologia de Porto ... Permissions Cite Icon Cite Search Site Citation Rui Luzzatto, Gustavo Sisson, Lucio Luzzatto, Marta Recktenvald, Newton Brucker; Psammoma Bodies and Cells ...
Tópico(s): Endometrial and Cervical Cancer Treatments
1996 - Karger Publishers | Acta Cytologica
M. Graziella Persico, Giuseppe Viglietto, G. Martini, Daniela Toniolo, Giacomo Paonessa, Claudio Moscatelli, Rosanna Dono, T. Vulliamy, Lucio Luzzatto, Michele D’Urso,
... author on: Oxford Academic PubMed Google Scholar Lucio Luzzatto, Lucio Luzzatto §Department of HaematologyHammersmith Hospital, London W12 OHS, UK ...
Tópico(s): Metabolism and Genetic Disorders
1986 - Oxford University Press | Nucleic Acids Research
Ana Rovlra, Thomas J. Vulliamy, Assumpció Pujades, Lucio Luzzatto, Joan-Luis Vives Corrons,
... author on: Oxford Academic PubMed Google Scholar Lucio Luzzatto, Lucio Luzzatto 1Department of Haematotogy, Royal Postgraduate Medical School, Hammersmith ...
Tópico(s): Neonatal Health and Biochemistry
1994 - Oxford University Press | Human Molecular Genetics
Khédoudja Nafa, Abderrezak Reghis, Naima Osmani, Lamia Baghli, M. Benabadji, Jean‐Claude Kaplan, Thomas J. Vulliamy, Lucio Luzzatto,
... author on: Oxford Academic PubMed Google Scholar Lucio Luzzatto Lucio Luzzatto 2Department of Haematology, Royal Postgraduate Medical School, Hammersmith ...
Tópico(s): Neonatal Health and Biochemistry
1993 - Oxford University Press | Human Molecular Genetics
... medicine: Gene transfer and gene therapy Professor Lucio Luzzatto, Professor Lucio Luzzatto Haematology Department Royal Postgraduate Medical School Hammersmith ... for more papers by this author Professor Lucio Luzzatto, Professor Lucio Luzzatto Haematology Department Royal Postgraduate Medical School Hammersmith Hospital ...
Tópico(s): Genomics and Rare Diseases
1992 - Wiley | Journal of Internal Medicine
Matilda Mkombachepa, Benjamin Khamis, Gration Rwegasira, Florence Urio, Julie Makani, Lucio Luzzatto,
... Sciences, TanzaniaSearch for more papers by this authorLucio Luzzatto, Lucio Luzzatto lluzzatto@blood.ac.tz orcid.org/0000- ... Sciences, TanzaniaSearch for more papers by this authorLucio Luzzatto, Lucio Luzzatto lluzzatto@blood.ac.tz orcid.org/0000-0003- ...
Tópico(s): Malaria Research and Control
2022 - Wiley | American Journal of Hematology
Lucio Luzzatto, Hanna I. Hyry, Arrigo Schieppati, Enrico Costa, Steven Simoens, Franz Schaefer, Jonathan C. P. Roos, Giampaolo Merlini, Helena Kääriäinen, Silvio Garattini, Carla E. M. Hollak, Giuseppe Remuzzi, Tiziano Barbui, Ariela Benigni, Enrico Costa, Erica Daina, Silvio Garattini, Donatella Gramaglia, Carla E. M. Hollak, Hanna I. Hyry, Helena Kaarinen, Christoph Licht, Lucio Luzzatto, Giampaolo Merlini, Rosario Notaro, Giuseppe Remuzzi, Franz Schaefer, Arrigo Schieppati, Steven Simoens,
Few instances of a single act of legislation have shifted industrial policy in the pharmaceutical industry like the Orphan Drugs Act did when it was signed in the USA in 1983. The Act was written to facilitate the development of drugs for rare diseases and health conditions, 1 US Food and Drug AdministrationOrphan Drug Act, Pub L. No. 97-414, 96 Stat. 2049. http://www.fda.gov/ForIndustry/DevelopingProductsforRareDiseasesConditions/HowtoapplyforOrphanProductDesignation/ucm364750.htmDate accessed: ...
Tópico(s): Pharmaceutical Economics and Policy
2018 - Elsevier BV | The Lancet
S. Galiano, Gian Franco Gaetani, A. Barabino, F Cottafava, H Zeitlin, M Town, Lucio Luzzatto,
Susceptibility to haemolytic anaemia after ingestion of fava beans has been investigated extensively in the Mediterranean, but favism has also been observed in other countries' including England,2 where variants of glucose-6-phosphate dehydrogenase other than the Mediterranean variant have been responsible. In general, all patients have very low glucose-6-phosphate dehydrogenase activity in red cells (<5% of normal activity). Favism is widely believed not to occur in subjects with the glucose-6-phosphate ...
Tópico(s): Erythrocyte Function and Pathophysiology
1990 - BMJ | BMJ
MartinF. Fey, JimS. Wainscoat, E.C. Mukwala, Adeyinka G. Falusi, TomJ. Vulliamy, Lucio Luzzatto,
Tópico(s): Folate and B Vitamins Research
1990 - Springer Science+Business Media | Human Genetics
David R. Greaves, Peter Fraser, Miguel Vidal, M. Hedges, David Ropers, Lucio Luzzatto, Frank Grosveld,
A SINGLE base-pair mutation (βs) in codon 6 of the human β-globin gene, causing a single amino-acid substitution, is the cause of sickle cell anaemia1. The mutant haemoglobin molecule, HbS, polymerizes when deoxygenated and causes deformation of the erythrocytes to a characteristic 'sickled' shape. Sickling of cells in small vessels causes painful crises and other life-threatening complications2,3. Although the molecular basis for sickle cell anaemia has been known for 30 years, no definitive treatment ...
Tópico(s): Iron Metabolism and Disorders
1990 - Nature Portfolio | Nature
David Walliker, G Beale, Lucio Luzzatto,
Tópico(s): Evolution and Genetic Dynamics
1990 - Nature Portfolio | Nature
Buran Kurdi-Haidar, Lucio Luzzatto,
Tópico(s): Hemoglobinopathies and Related Disorders
1990 - Elsevier BV | Molecular and Biochemical Parasitology
Letizia Foroni, J. Földi, E Matutes, D Catovsky, Nathan O’Connor, Richard Baer, A. Förster, Terence H. Rabbitts, Lucio Luzzatto,
Summary We have studied the arrangement of the α, β and γT cell receptor (TCR) genes in 27 patients with T cell lymphoproliferative disorders. Nine patients had acute lymphoblastic leukaemia (T‐ALL), nine patients had prolympho‐cytic leukaemia (PLL), six patients presented with a T‐CLL/T‐lymphocytosis syndrome, two patients had Sezary syndrome (SS) and one patient had HTLV‐I positive T‐cell leukaemia/ lymphoma (ATLL). α TCR gene rearrangement could be demonstrated by the use of three available probes ...
Tópico(s): Galectins and Cancer Biology
1987 - Wiley | British Journal of Haematology
Letizia Foroni, J. Földi, E Matutes, D Catovsky, Nathan O’Connor, Richard Baer, A. Förster, Terence H. Rabbitts, Lucio Luzzatto,
We have studied the arrangement of the alpha, beta and gamma T cell receptor (TCR) genes in 27 patients with T cell lymphoproliferative disorders. Nine patients had acute lymphoblastic leukaemia (T-ALL), nine patients had prolymphocytic leukaemia (PLL), six patients presented with a T-CLL/T-lymphocytosis syndrome, two patients had Sezary syndrome (SS) and one patient had HTLV-I positive T-cell leukaemia/lymphoma (ATLL). alpha TCR gene rearrangement could be demonstrated by the use of three available ...
Tópico(s): Galectins and Cancer Biology
1987 - Wiley | British Journal of Haematology
K. H. Th'ng, Gurjivan Garewal, Robert E. Kearney, F. Rassool, J V Melo, Hillary D. White, D Catovsky, Letizia Foroni, Lucio Luzzatto, J M Goldman,
We have established 3 new EBV-negative cell lines, designated Sc-1, Ri-1 and Ci-1, from patients with B-cell lymphoma/leukemia. We characterized them by cytogenetics and by study of surface membrane antigens with a panel of monoclonal antibodies (MAbs), surface and cytoplasmic immunoglobulin (Ig) expression and Ig heavy- and light-chain genes. All 3 lines had a 14q+ abnormality. Ri-1 also had translocations involving chromosomes 2, 8 and 18. Ci-1 also had abnormalities involving chromosomes 2, 8 and ...
Tópico(s): Chronic Lymphocytic Leukemia Research
1987 - Wiley | International Journal of Cancer
Tullio Meloni, S Cutillo, Ugo Testa, Lucio Luzzatto,
Tópico(s): Hyperglycemia and glycemic control in critically ill and hospitalized patients
1987 - Elsevier BV | Early Human Development
Junia V. Melo, Vasantha Brito‐Babapulle, Letizia Foroni, D S Robinson, Lucio Luzzatto, Daniel Catovsky,
Abstract Leukaemic cells from 2 patients with B‐prolymphocytic leukaemia were immortalized in vitro by means of Epstein‐Barr virus and phorbol‐ester TPA. The resulting cell lines, named JVM‐2 and JVM‐3, have been growing continuously in liquid culture for more than one year. JVM‐2 is characterized cytogenetically by t(11;14)(q13;q32), and JVM‐3 by trisomy 12. The immunoglobulin (Ig) heavy‐and light‐chain genes showed the same pattern of rearrangement in both lines as in the original prolymphocytes ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
1986 - Wiley | International Journal of Cancer
G. Martini, Daniela Toniolo, Tom Vulliamy, Lucio Luzzatto, Rosanna Dono, Giuseppe Viglietto, Giacomo Paonessa, Michele D’Urso, M. Graziella Persico,
Tópico(s): Biochemical and Molecular Research
1986 - Springer Nature | The EMBO Journal
Lucio Luzzatto, Peter N. Goodfellow,
Tópico(s): Dermatological and Skeletal Disorders
1989 - Nature Portfolio | Nature
Shiro Miwa, Lucio Luzzatto, R Rosa, D.E. Paglia, W. Schröter, Antonio De Flora, H Fujii, PG Board, Ernest Beutler,
In 1977 the Red Cell Enzyme Expert Panel of the International Committee for Standardization in Haematology (ICSH) issued recommended methods for red cell enzyme analysis (Beutler et al. 1977).These methods have made it possible to measure red cell enzyme activity with reliable and convenient techniques, and to compare results obtained in different laboratories.After the publication of the ICSH recommended methods, pyrimidine 5'-nucleotidase (P5N) deficiency came to our attention.This enzyme was first ...
Tópico(s): Acute Lymphoblastic Leukemia research
1989 - Wiley | Clinical & Laboratory Haematology
Tópico(s): Blood groups and transfusion
1989 - Elsevier BV | Baillière s Clinical Haematology
Letizia Foroni, Michael Laffan, Thomas Boehm, Terence H. Rabbitts, D Catovsky, Lucio Luzzatto,
Abstract Two distinct types of T-cell receptors (TCR), designated alpha beta and gamma delta, have been identified on the surface of T cells. In the adult, T cells bearing the gamma delta TCR are a minority and they have the phenotype CD3+, CD4-, CD8-/+. By using appropriate probes, rearrangements of the TCR alpha, beta, and gamma genes have been extensively investigated in a variety of lymphoproliferative disorders. Because the TCR delta gene has been cloned only recently, no comparable information ...
Tópico(s): CAR-T cell therapy research
1989 - Elsevier BV | Blood
Tom Vulliamy, Wanchai Wanachiwanawin, P.J. Mason, Lucio Luzzatto,
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
1989 - Oxford University Press | Nucleic Acids Research
O Hanscombe, Miguel Vidal, Jaspal Kaeda, Lucio Luzzatto, David R. Greaves, Frank Grosveld,
Using the dominant control region (DCR) sequences that flank the beta-globin gene locus, we have been able to achieve high-level expression of the human alpha-globin gene in transgenic mice. Expression in fetal liver and blood is copy number dependent and at levels comparable to that of the endogenous mouse alpha-globin genes. Transgenic fetuses with high-copy numbers of the transgene suffer severe anemia and die before birth. Using a construct with both the human alpha- and beta-globin genes and ...
Tópico(s): Virus-based gene therapy research
1989 - Cold Spring Harbor Laboratory Press | Genes & Development
L. Terrenato, Shikshya Shrestha, Kunda Dixit, Lucio Luzzatto, G. Modiano, G. Morpurgo, Paolo Arese,
The Terai region of Nepal has been known to be heavily malarious since remote times, and it has, therefore, been regarded as uninhabitable by most Nepalese people. The Tharu people, who have been living in the Terai for centuries, were reputed to have an innate resistance to malaria. Following successful control of malaria by the Nepal Malaria Eradication Organization (NMEO), a large and heterogeneous non-Tharu population now inhabits the Terai along with Tharus. By analysing NMEO records, we have ...
Tópico(s): Mosquito-borne diseases and control
1988 - Maney Publishing | Annals of Tropical Medicine and Parasitology
Sean Whittaker, Letizia Foroni, Lucio Luzzatto, I. A. Lampert, PETER AMLOTT, ALISTAIR MUNRO, Robin Russell Jones,
Lymphomatoid granulomatosis and lethal midline granuloma are both characterized histologically by atypical pleomorphic angiocentric infiltrates. Whether these conditions are malignant lymphoproliferative disorders remains controversial. Here we report the results of studies carried out in a patient with coeliac disease, who developed recurrent self-healing subcutaneous nodules with the histological changes of lymphomatoid granulomatosis and an invasive nasal tumour with the histological features ...
Tópico(s): Lymphoma Diagnosis and Treatment
1988 - Oxford University Press | QJM
Mordechai E. Kislev, Ofer Bar‐Yosef,
... 1016/j.quaint.2017.09.040Dan L. Longo, Lucio Luzzatto, Paolo Arese Favism and Glucose-6-Phosphate Dehydrogenase ...
Tópico(s): Cassava research and cyanide
1988 - University of Chicago Press | Current Anthropology
Produção Nacional
Revisado por pares
Antonio Piga, Lucio Luzzatto, P. Capalbo, Silvia Gambotto, Fernando Tricta, V. Gabutti Pediatric,
European Journal of HaematologyVolume 40, Issue 4 p. 380-381 HIGH-DOSE DESFERRIOXAMINE AS A CAUSE OF GROWTH FAILURE IN THALASSEMIC PATIENTS A. Piga, Corresponding Author A. PigaDepartment and Auxology Center University of Turin ItalySearch for more papers by this authorL. Luzzatto, Corresponding Author L. LuzzattoDepartment and Auxology Center University of Turin ItalySearch for more papers by this authorP. Capalbo, Corresponding Author P. CapalboDepartment and Auxology Center University of Turin ...
Tópico(s): Erythrocyte Function and Pathophysiology
1988 - Wiley | European Journal Of Haematology
Nicholas S. Foulkes, P.P.Pandolfi de Rinaldis, J. Macdonnell, Nicholas C.P. Cross, Lucio Luzzatto,
Tópico(s): Molecular Biology Techniques and Applications
1988 - Oxford University Press | Nucleic Acids Research