Ilaria Gandolfini, Carlo Buzio, Paola Zanelli, Alessandra Palmisano, Elena Cremaschi, Augusto Vaglio, Giovanni Piotti, Luigi Melfa, Gaetano La Manna, G. Feliciangeli, Maria Cappuccilli, Maria Scolari, Irene Capelli, Laura Panicali, Olga Baraldi, S. Stefoni, Andrea Buscaroli, Lorenza Ridolfi, Antonietta D’Errico, Gianni Cappelli, Decenzio Bonucchi, E. Rubbiani, A Albertazzi, Anita Mehrotra, Paolo Cravedi, Umberto Maggiore,
Pretransplant donor biopsy (PTDB)-based marginal donor allocation systems to single or dual renal transplantation could increase the use of organs with Kidney Donor Profile Index (KDPI) in the highest range (e.g. >80 or >90), whose discard rate approximates 50% in the United States. To test this hypothesis, we retrospectively calculated the KDPI and analyzed the outcomes of 442 marginal kidney transplants (340 single transplants: 278 with a PTDB Remuzzi score <4 [median KDPI: 87; interquartile range (IQR): ...
Tópico(s): Renal and Vascular Pathologies
2014 - Elsevier BV | American Journal of Transplantation
Michele Carbognani, Andrea Piotti, Stefano Leonardi, Luigi Pasini, Ilaria Spanu, Giovanni G. Vendramin, Marcello Tomaselli, Alessandro Petraglia,
Abstract Background and Aims At the rear edge of the distribution of species, extreme isolation and small population size influence the genetic diversity and differentiation of plant populations. This may be particularly true for Arctic-alpine species in mid-latitude mountains, but exactly how peripherality has shaped their genetic and reproductive characteristics is poorly investigated. The present study, focused on Salix herbacea, aims at providing new insights into the causes behind ongoing demographic ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2019 - Oxford University Press | Annals of Botany
Chiara Lestuzzi, Gian Luigi Nicolosi, Salvatore Biasi, Patrizia Piotti, D Zanuttini,
We evaluated the correlations between electrocardiographic ST-T changes (negative T waves, ST segment elevation) and echocardiographic diagnosis of neoplastic infiltration of the myocardium in 95 patients with neoplastic masses in contact with the heart. We compared echocardiographic results to computed tomography, nuclear magnetic resonance, surgery or autopsy data in 49 patients: the concordance was 86 percent. Significant ST-T changes were present in 77.7 percent of the patients with myocardial ...
Tópico(s): Cardiovascular Function and Risk Factors
1989 - Elsevier BV | CHEST Journal
Luisa Diomede, Sara Baroni, Ada De Luigi, Arianna Piotti, Jacopo Lucchetti, Claudia Fracasso, Luca Russo, Valerio Bonaldo, Nicolò Panini, Federica Filippini, Fabio Fiordaliso, Alessandro Corbelli, Marten Beeg, Massimo Pizzato, Francesca Caccuri, Marco Gobbi, Emiliano Biasini, Arnaldo Caruso, Mario Salmona,
The rapid spread of the pandemic caused by the SARS-CoV-2 virus has created an unusual situation, with rapid searches for compounds to interfere with the biological processes exploited by the virus. Doxycycline, with its pleiotropic effects, including anti-viral activity, has been proposed as a therapeutic candidate for COVID-19 and about twenty clinical trials have started since the beginning of the pandemic. To gain information on the activity of doxycycline against SARS-CoV-2 infection and clarify ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Multidisciplinary Digital Publishing Institute | Viruses
Luigi Caputi, Maria Rita Carriero, Chiara Falcone, Eugenio Parati, Patrizia Piotti, Carlo Materazzo, Gian Paolo Anzola,
Background Patent foramen ovale (PFO) has been investigated in several conditions apart from cryptogenic ischemic stroke. Contrast transesophageal echocardiography (cTEE) is the gold standard for the diagnosis, although it has some known limitations. Contrast transcranial Doppler (cTCD) allows a semiquantitative estimation of right-to-left shunt (RLS) volume. The aims of our study were to confirm the diagnostic accuracy of cTCD in PFO diagnosis and to compare the abilities of cTCD and cTEE to detect ...
Tópico(s): Congenital Heart Disease Studies
2009 - Elsevier BV | Journal of Stroke and Cerebrovascular Diseases
Marten Beeg, Sara Baroni, Arianna Piotti, Alessia Porta, Ada De Luigi, Alfredo Cagnotto, Marco Gobbi, Luisa Diomede, Mario Salmona,
We developed and validated a technology platform for designing and testing peptides inhibiting the infectivity of SARS-CoV-2 spike protein-based pseudoviruses. This platform integrates target evaluation, in silico inhibitor design, peptide synthesis, and efficacy screening. We generated a cyclic peptide library derived from the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein and the angiotensin-converting enzyme 2 (ACE2) receptor. The cell-free validation process by ELISA competition ...
Tópico(s): vaccines and immunoinformatics approaches
2023 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Martina Barchitta, Andrea Maugeri, Giuliana Favara, Roberta Magnano San Lio, M C La Rosa, Fortunato D’Ancona, Antonella Agodi, Paola Murgia, María Dolores Masiá, I Mura, Silvio Brusaferro, Luca Arnoldo, Carla Di Stefano, Fernando Lucchese, Marı́a Cristina Lugano, Stefano Tardivo, Francesca Moretti, Mara Bernasconi, Francesco Pappalardo, Cesira Pasquarella, Ennio Sicoli, Maria Teresa Montagna, Giuseppina Caggiano, O. De Giglio, Salesia Fenaroli, Raffaele Squeri, Giuseppe Cannavò, Alfredo Pulvirenti, Samantha Catalano, Anna Rita Mattaliano, Giacomo Castiglione, Marinella Astuto, Giuseppa La Camera, E Panascia, Anna Maria Longhitano, Giorgio Scrofani, M.R. Gallea, Pietro Civello, Michele Milazzo, Giuseppe Calamusa, Antonino Giarratano, A. Di Benedetto, G. Rizzo, Giuseppe Manta, C. Angelone, Roberta Mancuso, Romano Tetamo, L. Mella, Ignazio Dei, Irene Pandiani, Antonino Cannistrà, Patrizia Piotti, Massimo Girardis, Alberto Barbieri, Savino Borracino, Roberto Palermo, D. Di Stefano, Riccardo Colombo, Anthony A. Romeo, Mariachiara Minerva, Leila Fabiani, Franco Marinangeli, Marcello Mario D’Errico, Abele Donati, Roberta Domizi, Sebastiana Saglimbene, Aida Bianco, Cesare Vittori, Giovanni Battista Orsi, M. Scibilia, Olivier Cala, Ida Di Giacinto, M.R. Amatucci, Tania Principi, Giovanni Di Fabio, V. Gobbini, Maria Patrizia Olori, Massimo Antonelli, Patrizia Laurenti, Luigi Condorelli, F. Ingala, Salvatore Russo, Elı́sio Costa, L. Canonico, Patrizia Farruggia, Míriam Cristina, Marina Sartini, Cristina Arrigoni, I. Galassi, Viviana Vinci,
Although healthcare-associated infections (HAIs) pose an extraordinary burden on public health, the impact of coronavirus disease 2019 (COVID-19) is still a matter of debate.To describe trends of HAIs in Italian intensive care units (ICUs) from 2006 to 2021, and to compare characteristics and outcomes of patients with or without COVID-19.We evaluated patients participating in the 'Italian Nosocomial Infections Surveillance in Intensive Care Units' (SPIN-UTI) project, who were admitted to ICUs for more ...
Tópico(s): Patient Satisfaction in Healthcare
2023 - Elsevier BV | Journal of Hospital Infection