Richard J. Smith, Gene H. Albrecht, John Damuth, M. Di Bacco, Mikael Fortelius, Philip D. Gingerich, Laurie R. Godfrey, Michael R. Sutherland, William L. Jungers, Steven R. Leigh, Mark D. Leney, Robert Foley, William R. Leonard, Marcia L. Robertson, Walter Leutenegger, Henry M. McHenry, Robert D. Martín, David J. Pilbeam, J. Michael Plavcan, P. E. Wheeler, Barry Wood, M Collard,
... 2014/406507Adrián Pablos, Asier Gómez-Olivencia, Alfonso García-Pérez, Ignacio Martínez, Carlos Lorenzo, Juan Luis Arsuaga From toe to head: Use of robust ...
Tópico(s): Bat Biology and Ecology Studies
1996 - University of Chicago Press | Current Anthropology
Amy T. Austin, Carlos L. Ballaré,
... González-Arzac, Ignacio Cerrudo, Miriam Izaguirre, Melisa Leone, Carlos Mazza, Laura Martínez, Luis Pérez, and Lucía Vivanco) for their unrelenting enthusiasm and ...
Tópico(s): Plant Parasitism and Resistance
2014 - Wiley | New Phytologist
Gundela Meyer, Alfredo Cabrera Socorro, Carlos G. Pérez‐García, Luis Martínez Millán, Nancy M. Walker, Daniel Caput,
To examine the role of the p53 homolog p73 in brain development, we studied p73 -/- , p73 +/- , E2F1 -/- , and reeler mutant mice. p73 in developing brain is expressed in Cajal-Retzius (CR) cells, the cortical hem, and the choroid plexus. p73-expressing CR cells are lost in p73 -/- embryos, although Reelin is faintly expressed in the marginal zone. Ectopic neurons in the p73 -/- preplate and cortical hem at embryonic day 12 implicate p73 in the early developmental program of the cortex; however, preplate partition and early ...
Tópico(s): Epigenetics and DNA Methylation
2004 - Society for Neuroscience | Journal of Neuroscience
Rodolfo Pérez Alamino, Carlos Martínez, Luis R. Espinoza,
Tópico(s): Autoimmune and Inflammatory Disorders
2013 - Springer Science+Business Media | Current Rheumatology Reports
Jose Luis Pérez‐Gracia, Pedro Berraondo, Iván Martínez‐Forero, Carlos Alfaro, Natalia Suárez, Alfonso Gúrpide, Bruno Sangro, Sandra Hervás‐Stubbs, María C. Ochoa, José A. Melero, Ignacio Melero,
Stimulating the innate and adaptive immunity against cancer necessitates the tricking of a system evolved to fight microbial pathogens and directing its activity towards transformed self-tissue. Efficacious interventions to start and sustain the response will probably require a number of agents to tamper simultaneously or sequentially with several immune mechanisms. Although master switches controlling various functions may exist, the goal of a curative immune response will probably demand the combined ...
Tópico(s): T-cell and B-cell Immunology
2009 - Future Medicine | Immunotherapy
Javier Molina‐Infante, Ángel Arias, Javier Alcedo, Ruth García‐Romero, Sergio Casabona, A. Prieto, Inés Modolell, Pedro L. Gonzalez-Cordero, Isabel Pérez‐Martínez, José Luis Martín-Lorente, Carlos Guarner‐Argente, M. Masiques, V Vila-Miravet, Roger García-Puig, Edoardo Savarino, Carlos Teruel, Cecílio Santander, Alfredo J. Lucendo,
BackgroundNumerous dietary restrictions and endoscopies limit the implementation of empiric elimination diets in patients with eosinophilic esophagitis (EoE). Milk and wheat/gluten are the most common food triggers.ObjectiveWe sought to assess the effectiveness of a step-up dietary strategy for EoE.MethodsWe performed a prospective study conducted in 14 centers. Patients underwent a 6-week 2-food-group elimination diet (TFGED; milk and gluten-containing cereals). Remission was defined by symptom improvement ...
Tópico(s): Esophageal and GI Pathology
2017 - Elsevier BV | Journal of Allergy and Clinical Immunology
Jesús Cámara-Almirón, Yurena Navarro, Luis Díaz‐Martínez, María Concepción Magno-Pérez-Bryan, Carlos Molina‐Santiago, J. R. A. Pearson, Antonio de Vicente, Alejandro Pérez‐García, Diego Romero,
Bacteria can form biofilms that consist of multicellular communities embedded in an extracellular matrix (ECM). In Bacillus subtilis, the main protein component of the ECM is the functional amyloid TasA. Here, we study further the roles played by TasA in B. subtilis physiology and biofilm formation on plant leaves and in vitro. We show that ΔtasA cells exhibit a range of cytological symptoms indicative of excessive cellular stress leading to increased cell death. TasA associates to the detergent- ...
Tópico(s): Legume Nitrogen Fixing Symbiosis
2020 - Nature Portfolio | Nature Communications
Produção Nacional
Revisado por pares
Valeria Romanelli, Julián Nevado, Mario F. Fraga, Alejandro Martin Trujillo, M. A. Mori, Luis Carlos Sainz Fernandez, Guiomar Pérez de Nanclares, Victor Martínez‐Glez, Guillermo Pita, H. Meneses, R Gracia, Sixto García‐Miñaúr, Purificación García de Miguel, Beatriz Lecumberri, José Ignacio Rodrı́guez, Anna González‐Neira, David Monk, Pablo Lapunzina,
Molecular studies in a patient with Beckwith–Wiedemann syndrome phenotype who developed two different tumours revealed an unexpected observation of almost complete loss of heterozygosity of all chromosomes. It is shown, by means of numerous molecular methods, that the absence of maternal contribution in somatic cells is due to high-degree (∼85%) genome-wide paternal uniparental disomy (UPD). The observations indicate that the genome-wide UPD results from diploidisation, and have important implications ...
Tópico(s): Epigenetics and DNA Methylation
2010 - BMJ | Journal of Medical Genetics
Yuniel Méndez‐Martínez, Marcelo García‐Guerrero, Guadalupe Fabiola Arcos‐Ortega, Luis Rafael Martínez‐Córdova, Stig Yamasaki-Granados, Juan Carlos Pérez‐Rodríguez, Edilmar Cortés‐Jacinto,
Tópico(s): Aquaculture disease management and microbiota
2017 - Elsevier BV | Aquaculture
Luis Latournerie, José Luis Chávez, Manuel Pérez, Carlos F. Hernández, Rodrigo Martínez, Luis Miguel Delgado Arias, Guillermo Castañón,
The main objective of this work was to know the types diversity and uses of the pepper, selection criteria and to get samples samples of the landraces. The studied system was a multi-cropping system with corn, beans, pepper and pumpkin (milpa), established in two stages: a) a survey on 60 land-owners from the community, in order to gather information of the crop and their croppin systems applied in the ‘milpa’, pach pakal (land useful for gardening) and back-yards. b) An etnobotanical exploration to ...
Tópico(s): Latin American rural development
2006 - University of Costa Rica | Agronomía Mesoamericana
Aldo Joel Villa Silva, Luis Pérez-Domínguez, Erwin Adán Martínez Gómez, Alejandro Alvarado‐Iniesta, Iván Juan Carlos Pérez-Olguín,
The supplier appraisal process is one of the most important decision problems for companies focused on improving supply chain costs. Supplier selection is typically a multi-criteria decision making (MCDM) issue, as there is a lot of uncertain information. In order to overcome this issue, The Pythagorean Fuzzy Set is applied to handle the uncertainties involved in comparing the alternatives, criteria and opinions of decision makers. At the same time, a potential of Dimensional Analysis is a technique ...
Tópico(s): Optimization and Mathematical Programming
2019 - Multidisciplinary Digital Publishing Institute | Symmetry
María José Gosalbes, Carlos David Esteban, José Luis Márquez Galán, Gaspar Pérez‐Martínez,
ABSTRACT The lactose operon from Lactobacillus casei is regulated by very tight glucose repression and substrate induction mechanisms, which made it a tempting candidate system for the expression of foreign genes or metabolic engineering. An integrative vector was constructed, allowing stable gene insertion in the chromosomal lactose operon of L. casei . This vector was based on the nonreplicative plasmid pRV300 and contained two DNA fragments corresponding to the 3′ end of lacG and the complete lacF ...
Tópico(s): Biopolymer Synthesis and Applications
2000 - American Society for Microbiology | Applied and Environmental Microbiology
Felipe Ávila, Guadalupe Echeverría, Druso Pérez, Martinez Carlos, Pablo Strobel, O. Castillo, Luis Villaroel, Diego Mezzano, Jaime Rozowski, Inés Urquiaga, Leighton Federico,
Background and Aims . Hyperferritinemia has been related with a wide spectrum of pathologies, including diabetes, cardiovascular disease, neurodegenerative disorders, and metabolic syndrome. The aim of this study was to investigate the association between hyperferritinemia and iron consumption. Methods and Results . Serum ferritin concentration was evaluated in 66 presumed healthy men, along with other clinical and biochemical markers of chronic diseases. A three-day food questionnaire was applied for ...
Tópico(s): Trace Elements in Health
2015 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity
José Luis Herráiz, Joan Ribé, Héctor Botella, Carlos Martínez‐Pérez, Humberto G. Ferrón,
Nursery areas are fundamental for the success of many marine species, particularly for large, slow-growing taxa with low fecundity and high age of maturity. Here, we examine the population size-class structure of the extinct gigantic shark Otodus megalodon in a newly described middle Miocene locality from Northeastern Spain, as well as in eight previously known formations (Temblor, Calvert, Pisco, Gatún, Chucunaque, Bahía Inglesa, Yorktown and Bone Valley). In all cases, body lengths of all individuals ...
Tópico(s): Fish Biology and Ecology Studies
2020 - Royal Society | Biology Letters
David Bienvenido-Huertas, Carlos Rubio-Bellido, Juan Luis Pérez-Ordóñez, Fernando Martínez‐Abella,
Reducing both the energy consumption and CO2 emissions of buildings is nowadays one of the main objectives of society. The use of heating and cooling equipment is among the main causes of energy consumption. Therefore, reducing their consumption guarantees such a goal. In this context, the use of adaptive setpoint temperatures allows such energy consumption to be significantly decreased. However, having reliable data from an external temperature probe is not always possible due to various factors. ...
Tópico(s): Wind and Air Flow Studies
2019 - Multidisciplinary Digital Publishing Institute | Energies
Salim Barquet-Muñoz, Silvia Patricia Villarreal-Colín, Luis A. Herrera, Ernesto Soto‐Reyes, Carlos Pérez‐Plasencia, Jaime Coronel-Martínez, Delia Pérez‐Montiel, Rafael Vázquez-Romo, David Cantú de León,
Metaplastic carcinoma of the breast (MCB) is a rare histological type of breast cancer. This study aimed to determine whether MCB exhibits shorter overall survival (OS) and disease-free survival (DFS) compared with other histologies that are considered unfavorable.We retrospectively analyzed 157 clinical file records of the Mexico City-based National Institute of Cancerology and compared the clinical characteristics and treatment of 24 patients with MCB, 37 patients with triple-negative invasive lobular ...
Tópico(s): Breast Cancer Treatment Studies
2015 - BioMed Central | BMC Cancer
López Castañeda, Nallely García‐Larragoiti, Alan Cano‐Méndez, Kenia Blancas-Ayala, Guadalupe Damian-Vázquez, Ana Itzel Perez-Medina, Luis David Chora-Hernández, Carlos Arean-Martínez, Martha Eva Viveros‐Sandoval,
Among COVID-19 hospitalized patients, high incidence of alterations in inflammatory and coagulation biomarkers correlates with a poor prognosis. Comorbidities such as chronic degenerative diseases are frequently associated with complications in COVID-19 patients. The aim of this study was to evaluate inflammatory and procoagulant biomarkers in COVID-19 patients from a public hospital in Mexico. Blood was sampled within the first 48 h after admission in 119 confirmed COVID-19 patients that were classified ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - SAGE Publishing | Clinical and Applied Thrombosis/Hemostasis
María José Gosalbes, Isabel Pérez‐Arellano, Carlos David Esteban, José Luis Márquez Galán, Gaspar Pérez‐Martínez,
The lactose operon, lacTEGF, of Lactobacillus casei ssp.casei ATCC393 [pLZ15 -] is encoding an antiterminator protein (LacT), the elements (LacE and LacF) of the lactose-specific phosphotransferase system (PTS) and a phospho-β-galactosidase (LacG).The lac operon is repressed by glucose and fructose and is induced by lactose, through the PTS/CcpA signal transduction system and an antiterminator mechanism, respectively.Furthermore, the antiterminator activity of LacT is also negatively modulated possibly ...
Tópico(s): Bacterial Genetics and Biotechnology
2001 - EDP Sciences | Dairy Science & Technology
María Teresa Hernández‐Huerta, Laura Pérez‐Campos Mayoral, Carlos Romero Díaz, Margarito Martínez Cruz, Gabriel Mayoral Andrade, Luis Manuel Sánchez Navarro, María del Socorro Pina-Canseco, Elí Cruz Parada, Ruth Martínez Cruz, Eduardo Pérez‐Campos Mayoral, Alma Dolores Pérez‐Santiago, Gabriela Vásquez Martínez, Eduardo Pérez‐Campos, Carlos Alberto Matias‐Cervantes,
The genomic sequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide are publicly available and are derived from studies due to the increase in the number of cases. The importance of study of mutations is related to the possible virulence and diagnosis of SARS-CoV-2. To identify circulating mutations present in SARS-CoV-2 genomic sequences in Mexico, Belize, and Guatemala to find out if the same strain spread to the south, and analyze the specificity of the primers used ...
Tópico(s): COVID-19 Clinical Research Studies
2020 - Wiley | Journal of Medical Virology
Víctor Rosenthal, Dennis G. Maki, Yatin Mehta, Hakan Leblebicioğlu, Ziad A. Memish, Haifaa H. Al-Mousa, Hanan H. Balkhy, Bijie Hu, Carlos Álvarez, Eduardo Alexandrino Medeiros, Anucha Apisarnthanarak, Lul Raka, Luis E. Cuéllar, Altaf Ahmed, Josephine Anne Navoa-Ng, Amani El‐Kholy, Souha S. Kanj, Ider Bat-Erdene, Wiesława Duszyńska, Nguyễn Văn Trường, Leonardo N. Pazmino, Lucy Chai See-Lum, Rosalía Fernández-Hidalgo, Gabriela Di-Silvestre, Farid Zand, Soňa Hlinková, Vladislav Belskiy, Hussain Al-Rahma, Marco Tulio Luque-Torres, Nesil Bayraktar, Zan Mitrev, Vaidotas Gurskis, Dale Fisher, Ilham B. Abu-Khader, Kamal Berechid, Arnaldo Rodríguez-Sánchez, Florin George Horhat, Osiel Requejo-Pino, N Hadjieva, Nejla Ben-Jaballah, Elías García-Mayorca, Luis Kushner-Dávalos, Srdjan Pasic, Luis E. Pedrozo-Ortiz, Eleni Apostolopoulou, Nepomuceno Mejía, May Osman Gamar-Elanbya, Kushlani Jayatilleke, Miriam de Lourdes-Dueñas, Guadalupe Aguirre-Ávalos, Diego Maurizi, Adriana Montanini, María Laura Spadaro, Lorenzo Santiago Marcos, Priscila Botta, Florencia Maria Jerez, Maria Chávez, Lucia Ramasco, Maria Isabel Colqui, Maria Silvia Olivieri, Ana Silvia Rearte, Gladys Edith Correa, P. Juárez, Paola Fabiana Gallardo, Miriam Patricia Brito, Gabriel Horacio Mendez, Julia Rosa Valdez, Lorena Paola Cardena, Jose Maria Harystoy, Gustavo Chaparro, Claudia Gabriela Rodriguez, Rodolfo Toomey, Maria de los Ángeles Caridi, Mônica Pereira Campanha Viegas, Marisa L Bernan, Adriana Romaní, Claudia Beatriz Dominguez, Luis Kushner Davalos, Rosana Richtmann, Camila Almeida Silva, Tatiane Rodrigues, Amaury Mielle Filho, Ernandi Dagoberto Seerig Palme, Aline Besen, Caroline Lazzarini, Caroline Batista Cardoso, Francisco Kennedy Scofoni Faleiros de Azevedo, Ana Paula Pinheiro, Aparecida Camacho, Bráulio Matias de Carvalho, Maria Jose Monteiro De Assis, Ana Paula Vasconcelos Carneiro, Maria Lilian Maciel Canuto, Keyla Harten Pinto Coelho, T.T.S.L. Moreira, Agamenon Alves Oliveira, Marcela Maria Sousa Colares, Marcia Maria De Paula Bessa, Tereza de Jesus Pinheiro Gomes Bandeira, Renata Amaral De Moraes, Danilo Amâncio Campos, Tânia Mara Lima De Barros Araújo, Maria Tereza Freitas Tenório, Simone Cristina de Amorim, Manuela Cristina Gouveia do Amaral, Julianne Da Luz Lima, Lindalva Pino Da Silva Neta, Caphiane Batista, Fabio Jorge De Lima Silva, Maria C. Ferreira De Souza, Katia Arruda Guimaraes, Julia Marcia Maluf Lopes, Karina Martins Nogueira Napoles, Lorena Luiza Silva Neto Avelar, Lilian Aguiar Vieira, Luis Gustavo De Oliveira Cardo, Christianne Fernandes Valente Takeda, Glaydson A. Ponte, Fco Eduardo Aguiar Leitão, Ricardo de Souza Kuchenbecker, Rodrigo Pires dos Santos, Erci Maria Onzi Siliprandi, Luiz Fernando Baqueiro Freitas, Ianick Souto Martins, Daiane Casi, Maria Angela Maretti Da Silva, S Blecher, Margarete Villins, Reinaldo Salomão, Solange Regina Oliveira Castro, Daniela Vieira da Silva Escudero, Mariana Andrade Oliveira Reis, Marcelo Mendonça, Valter Furlan, Antônio Cláudio do Amaral Baruzzi, Tarquino Eristidesg Sanchez, Marina Moreira, Wania Vasconcelos de Freitas, Leonardo Passos de Souza, V. Velinova, N Hadjieva, Michael M. Petrov, Dimitar Georgiev Karadimov, Emil D. Kostadinov, Violeta Jivkova Dicheva, Chaohua Wang, Xiuqin Guo, Xihua Geng, Shufang Wang, Jinzhi Zhang, Ling Zhu, Shufang Zhuo, Chunli Guo, Lili Tao, Ruisheng Li, Kun Liu, Xuesong Yang, LI Yi-min, Pu Mao, Changan Li, Yiang Shumei, Wu Kangxiong, Lin Meiyi, Guxiang Ye, Zi-Qin Xu, Yao Suo, Song Li-qiang, Luis Marino Cañas Giraldo, Elsa Margarita Trujillo Ramirez, Paola Andrea Rios, Juan Carlos Torres Millan, Edwin Giovanny Chapeta Parada, Andres Eduardo Mindiola Rochel, Andres H. Corchuelo Martinez, Ana Marãa Perez Fernandez, Nayide Barahona-Guzmán, Alfredo Lagares Guzman, Marena Rodríguez-Ferrer, Yazmin Leon Vega, Heidi Johanna Munoz, Germán Camacho‐Moreno, Sandra Liliana Romero Torres, Herlidia Taboada Hernandez, Ismael A. Valderrama MarquezClaudia Linares, Monica Espinosa Valencia, Lusayda Sanchez Corrales, Sandra Milena Bonilla, Jorge Ivan Marin Uribe, David Yepes Gomez, Javier Martínez, Luz Dary Burgos Florez, Johanna Osorio, Dagoberto Santofimio, L Cortés, Wilmer E. Villamil‐Gómez, Gabriel Gutierrez, Adela Arguello Ruiz, Carlos Gonzalez Fuentes, Antonio Solano Chinchilla, Ivar Calvo Hernandez, Olber Chavarría Ugalde, Humberto Guanche Garcell, Clara Morales Perez, Selin Bardak, Sec inodot l Ozkan, Nepomuceno Mejía, Adrian M. Puello Guerrero Glenny Mirabal, Margarita Delgado, Ramona Severino, Eliesel Lacerda, Gilda Tolari, María Marcela Bovera, Diego Barahona Pinto, P González, Gasdali Santacruz, Nelly Alquinga, Celso Zaruma, Nelson Remache, Diego Morocho, Mario F Arboleda, M. C. Navarro Zapata, María Fernanda Garcia, Fabricio Picoita, Jorge Luis Vélez Páez, M. Valle, Estuardo Salgado Yepez, Diego Morocho Tutillo, Ricardo Mora, Andrea Peña Padilla, Mayra Chango, Karina Cabezas, Shirley Tenorio López, Ana Lucía Bonilla Escudero, Gladys Tatiana Sánchez, Hugo Alberto Gonzalez Flores, María Fernanda Garcia, Islam Abdullorziz Ghazi, Mohamed Hassan, Ghada Ismail, Reham Hamed, Mona Mohiedden Abdel-Halim, May Abd El-Fattah, Doaa M. Abdelaziz, Zeinab Salah Seliem, Rasha Elsherif, Reham Ali Dewdar, Abeer Ahmed Mohmed, Lamiaa Abdel-Fatteh Ahmed, Lilian de Jesús Machuca, Concepcion Bran De Casares, Prokopis Kithreotis, Maria Daganou, Dimitrios Veldekis, Maria Kartsonaki, Achilleas Gikas, Marco Tulio Luque Torres, Denis Padgett, Doris Maribel Rivera, Namita Jaggi, Camilla Rodrigues, Bhagyesh Shah, Keyur Parikh, Jigar Patel, Riya Thakkar, Murali Chakravarthy, B.N. Gokul, R. Sukanya, Leema Pushparaj, Thejas Vini, Sukanya Rangaswamy, Saroj Kumar Patnaik, V Venkateshwar, Biju John, Shamsher Dalal, Suneeta Sahu, Samir Sahu, Banambar Ray, Sudhiranjan Misra, Nisith Mohanty, Biraj Mohan Mishra, Prafulla Sahoo, Naresh Parmar, Sanghamitra Mishra, Basanta Kumar Pati, Santosh Kumar Singh, Bhabani Shankar Pati, Aparajita Panda, Swarna Banergee, Dipankar Padhihari, Soumya Samal, Samir Sahu, Karthikeya Varma, Velu Pandi Suresh Kumar, Ram Gopalakrishnan, Nagarajan Ramakrishnan, Babu K. Abraham,
We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC' ...
Elsevier BV
Juan Carlos Pérez-Razo, Luis Javier Cano-Martínez, Gilberto Vargas‐Alarcón, Samuel Canizales‐Quinteros, Nancy Martínez‐Rodríguez, Patricia Canto, Bladimir Roque‐Ramírez, Carlos Palma‐Flores, Rosa Lilia Esteban-Martínez, Luz Berenice López-Hernández, David Rojano‐Mejía, Ramón Mauricio Coral‐Vázquez,
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) have been associated with diastolic blood pressure, hypertension, and other cardiovascular diseases; however, results of these studies are still controversial. In this study, we sought to determine whether 2 functional variants (rs1801133 and rs13306560) within the MTHFR are associated with hypertension in Mexican-Mestizos.We performed a case-control study with 1214 subjects including adults and children to test for the association of both ...
Tópico(s): Nutritional Studies and Diet
2015 - Lippincott Williams & Wilkins | Circulation Cardiovascular Genetics
Jose Luis de Serdio, A. Villar, José Carlos Martínez Ávila, Marı́a Pérez-Vázquez, José Jesús Martín Martín, Claudio Fuentes, J. Gil-Curbelo, Ruth Marcos Hernández, Marcos Suñer, M. Espiñeira, Juan J. Artazkoz, Juan A. Saavedra,
Using chemotherapy as a part of each treatment fraction remains unexplored. This study integrates the concomitant administration of carboplatin with hyperfractionated irradiation by optimizing chemopotentiation through carboplatin administration with each irradiation fraction.From February 1993 to August 1996, 52 patients with advanced head and neck cancer were treated on a twice-a-day chemoradiotherapy schedule. Each fraction consisted of 115 cGy preceded by 5 mg/m2 of carboplatin. Treatment was ...
Tópico(s): Brain Metastases and Treatment
1998 - Wiley | Head & Neck
Jaime A. Cardona‐Ospina, Kovy Arteaga‐Livias, Wilmer E. Villamil‐Gómez, Carlos E. Pérez‐Díaz, D. Katterine Bonilla‐Aldana, Álvaro Mondragón-Cardona, Marco A. Solarte-Portilla, Ernesto Martínez, José Oñate, Eduardo López‐Medina, Pío López, Juan Carlos Navarro, Luis A. Pérez-García, Euler Mogollon‐Rodriguez, Alfonso J. Rodríguez‐Morales, Alberto Paniz‐Mondolfi,
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread throughout Latin America, a region swept by multiple previous and ongoing epidemics. There are significant concerns that the arrival of COVID-19 is currently overlapping with other viruses, particularly dengue, in various endo-epidemic regions across South America. In this report, we analyzed trends for both viral infections in Colombia during the first 20 epidemiological ...
Tópico(s): COVID-19 Clinical Research Studies
2020 - Wiley | Journal of Medical Virology
Álvaro Sebastián‐Serrano, Tobías Engel, Laura de Diego‐Garcia, Luis Alcides Olivos-Oré, Marina Arribas-Blázquez, Carlos Martínez-Frailes, Carmen Pérez-Díaz, José Luís Millán, Antonio R. Artalejo, Marı́a Teresa Miras-Portugal, David C. Henshall, Miguel Díaz‐Hernández,
Hypomorphic mutations in the gene encoding the tissue-nonspecific alkaline phosphatase (TNAP) enzyme, ALPL in human or Akp2 in mice, cause hypophosphatasia (HPP), an inherited metabolic bone disease also characterized by spontaneous seizures. Initially, these seizures were attributed to the impairment of GABAergic neurotransmission caused by altered vitamin B6 (vit-B6) metabolism. However, clinical cases in human newborns and adults whose convulsions are refractory to pro-GABAergic drugs but controlled ...
Tópico(s): Neurogenetic and Muscular Disorders Research
2016 - Oxford University Press | Human Molecular Genetics
Produção Nacional
Revisado por pares
Roger Iván Rodríguez‐Vivas, Luis Carlos Pérez-Cogollo, J.A. Rosado-Aguilar, Melina Maribel Ojeda-Chí, Iris Trinidad-Martínez, Robert J. Miller, Andrew Yongsheng Li, Adalberto Pérez de León, Felix D. Guerrero, Guilherme Klafke,
Ticks and the diseases they transmit cause great economic losses to livestock in tropical countries. Non-chemical control alternatives include the use of resistant cattle breeds, biological control and vaccines. However, the most widely used method is the application of different chemical classes of acaricides and macrocyclic lactones. Populations of the cattle tick, Rhipicephalus (Boophilus) microplus, resistant to organophosphates (OP), synthetic pyrethroids (SP), amitraz and fipronil have been reported ...
Tópico(s): Insect and Pesticide Research
2014 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology
Carlos Cuadrado‐Collados, J. Farrando-Pérez, Manuel Martínez Escandell, Luis A. Ramírez-Montoya, J.Á. Menéndez, Ana Arenillas, Miguel A. Montes‐Morán, Joaquín Silvestre‐Albero,
A series of xerogels with a properly designed porous structure and surface chemistry have been synthesized and evaluated as a host structure to promote the nucleation and growth of methane hydrates. Organic xerogels (OGs) have been synthesized from resorcinol-formaldehyde mixtures using a sol-gel approach and microwave heating. These xerogels are hydrophilic in nature and possess designed meso/macrocavities in the pore size range 5–55 nm. Carbon xerogels (CGs) have been synthesized from their organic ...
Tópico(s): Atmospheric and Environmental Gas Dynamics
2020 - Elsevier BV | Chemical Engineering Journal
Juan Dubrot, Francisca Milheiro, Carlos Alfaro, Asís Palazón, Iván Martínez‐Forero, Jose Luis Pérez‐Gracia, Aizea Morales‐Kastresana, José Lorenzo Romero-Trevejo, María C. Ochoa, Sandra Hervás‐Stubbs, Jesús Prìeto, Maria Jure-Kunkel, Lieping Chen, Ignacio Melero,
Tópico(s): T-cell and B-cell Immunology
2010 - Springer Science+Business Media | Cancer Immunology Immunotherapy
Carlos Estevez‐Fraga, José Luis López-Sendón, Juan Carlos Martínez‐Castrillo, Jesús Pérez‐Pérez, Michele Matarazzo, Pedro Ruiz, Agustín Querejeta, Ricardo Rigual, Ignacio J. Posada Rodríguez, Mónica Kurtis, María Rodríguez‐Oroz, M. R. Luquín, Mar Carmona‐Abellán, Justo García-Yébenes,
Neuroacanthocytosis (NA) comprises the association of movement disorders (MD) and spiny erythrocytes [1]. Autosomal recessive chorea-acanthocytosis (ChAc) is one of the core NA syndromes [2]. It is caused by mutations in the vascular protein sorting 13 homolog A gene (VPS13 A) [3,4] which encodes for the chorein protein [5]. Its prevalence is estimated to be around 1000 cases worldwide [6]. However, some areas such as the Japanese or the French-Canadian community [7] may have a higher prevalence.
Tópico(s): Genetic Neurodegenerative Diseases
2017 - Elsevier BV | Parkinsonism & Related Disorders
Eduardo López–Urrutia, Jossimar Coronel-Hernández, Verónica García-Castillo, Carlos Contreras-Romero, Antonio Daniel Martínez-Gutiérrez, Diana Estrada-Galicia, Luis I. Terrazas, César López‐Camarillo, Héctor Aquiles Maldonado-Martínez, Nadia Jacobo‐Herrera, Carlos Pérez‐Plasencia,
MicroRNAs are non-coding short RNAs that target the 3′ untranslated region of messenger RNAs (mRNAs) and lead to their degradation or to translational repression. Several microRNAs have been designated as oncomirs, owing to their regulating tumor suppressor genes. Interestingly, a few of them have been found to target multiple genes whose simultaneous suppression contributes to the development of a tumoral phenotype. Here, we have showed that miR-26a is overexpressed in colorectal cancer data obtained ...
Tópico(s): Cancer-related molecular mechanisms research
2017 - SAGE Publishing | Tumor Biology
Carlos Alfaro, Natalia Suárez, Carmen Oñate, Jose Luis Pérez‐Gracia, Iván Martínez‐Forero, Sandra Hervás‐Stubbs, Inmaculada Rodríguez, Guiomar Pérez, Elixabet Bolaños, Asís Palazón, Miguel F. Sanmamed, Aizea Morales‐Kastresana, Álvaro González, Ignacio Melero,
Dendritic cells (DC) are endowed with the ability to cross-present antigens from other cell types to cognate T cells. DC are poised to meet polymorphonuclear leukocytes (PMNs) as a result of being co-attracted by interleukin-8 (IL-8), for instance as produced by tumor cells or infected tissue. Human monocyte-derived and mouse bone marrow-derived DC can readily internalize viable or UV-irradiated PMNs. Such internalization was abrogated at 4°C and partly inhibited by anti-CD18 mAb. In mice, DC which ...
Tópico(s): T-cell and B-cell Immunology
2011 - Public Library of Science | PLoS ONE