Ivanka Tsacheva, Maria Radanova, Nadezhda Todorova, Т. Аргирова, Uday Kishore,
Tópico(s): T-cell and B-cell Immunology
2006 - Elsevier BV | Molecular Immunology
Jean‐Pierre Allain, Ivanka Mihaljević, Maria Isabel González-Fraile, Knut Gubbe, Lene Holm‐Harritshøj, José-María García-García, Ewa Brojer, Christian Erikstrup, Mona Saniewski, Lorenz Wernish, Lydia Bianco, Henrik Ullum, Daniel Candotti, Nico Lelie, Wolfram H. Gerlich, Michael Chudy,
Background Occult hepatitis B virus ( HBV ) infection ( OBI ) is identified in 1:1000 to 1:50,000 E uropean blood donations. This study intended to determine the infectivity of blood products from OBI donors. Study Design and Methods Recipients of previous donations from OBI donors were investigated through lookback (systematic retrieval of recipients) or traceback (triggered by clinical cases). Serologic and genomic studies were undertaken on consenting donors and recipients. Multiple variables potentially ...
Tópico(s): Blood donation and transfusion practices
2013 - Wiley | Transfusion
Branimir Ivanov, Ivanka Spassova, Maria Milanova, G. Tyuliev, M. Христова,
The effect of the addition of small amounts of rare earths (Ln=La, Ce, Nd and Gd) to alumina supported copper-cobalt spinel oxide on the catalysts efficiency in CO and CH4 oxidation and in NO decomposition was investigated. Samples of Ln/CuCo/Al catalyst were prepared and characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), atomic absorption spectroscopy (AAS), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS), H2-temperature-programmed reduction (H2-TPR), ...
Tópico(s): Nanomaterials for catalytic reactions
2015 - Elsevier BV | Journal of Rare Earths
Maria Ivanka Milić, Talia Carl, Ronald M. Rapee,
A growing body of evidence points to a strong overlap between selective mutism (SM) and social anxiety disorder in children, specifically with regard to characteristics such as social reticence and anxiety. Yet few studies have directly compared these populations, especially with young children. This study compared 25 children (aged 3–7 years) with a primary diagnosis of SM, 17 children with a primary diagnosis of social anxiety disorder and 15 non-clinical controls using interviews and questionnaires ...
Tópico(s): Stuttering Research and Treatment
2020 - Elsevier BV | Behaviour Research and Therapy
Michiel J. Bakkum, Milan C. Richir, Paraskevi Papaioannidou, Robert Likić, Emílio J. Sanz, Thierry Christiaens, João Costa, Romaldas Mačiulaitis, Lorena Dima, Jamie J. Coleman, Jelle Tichelaar, Michiel A. van Agtmael, Ivanka Atanasova, María Ganeva, Emil Gatchev, I. Kostadinova, Suzana Mimica Matanović, Dinko Vitezić, Greta Wozniak, E. Kmonickova, Karel Urbánek, Per Damkier, Risto Huupponen, Marine Auffret, Théodora Bejan‐Angoulvant, Laurent Chouchana, Jean‐Luc Cracowski, Milou‐Daniel Drici, J.L. Faillie, Hélène Geniaux, Mathiéu Molimard, D. Orlikowski, Karine Palin, Y-M Pers, Nicolas Picard, Nadine Lana Simon, Éric Toussirot, Rainer H. Böger, Ingolf Cascorbi, Shannon Mueller, Ralf Regenthal, Matthias Schwab, Markus Schwaninger, Petra Thuermann, L. Wojnowski, Dimitrios Kouvelas, Pál Riba, David Kerins, David Williams, Mimma Cosentino, Fabrizio De Ponti, Amelia Filippelli, Ryan Leone, Vittorio Locatelli, Baiba Jansone, Romaldas Gulbinovic, Janet Mifsud, Jan J. Braszko, Ivan Kocić, Luiza Breitenfeld, M. Castelo‐branco, Simona Conea, Ioan Magyar, Sebastjan Bevc, Mojca Krzan, M. L. Bernal, Dolors Capellà, Antonio J. Carcas, Francisco J. de Abajo, M. Lopez‐rico, M. Isabel Lucena, Caridad Pontes, Emílio J. Sanz, Ylva Böttiger, Madeleine Le Grevès, Itte de Waard‐Siebinga, Ben Janssen, Wilma Knol, Rahul Pandit, Floor van Rosse, Georgette A. Dent, Albert Ferro, A. W. Hitchings, Vandna Kapil, K. D. Linton, Yoon K. Loke, Michael Okorie, Richard David Plumb, Sarah Pontefract, Sajeev Ranmuthu, Anthony Sampson, H. K. R. Thanacoody, Jonathan P. Whitfield, Kurt Wilson,
Sharing and developing digital educational resources and open educational resources has been proposed as a way to harmonize and improve clinical pharmacology and therapeutics (CPT) education in European medical schools. Previous research, however, has shown that there are barriers to the adoption and implementation of open educational resources. The aim of this study was to determine perceived opportunities and barriers to the use and creation of open educational resources among European CPT teachers ...
Tópico(s): Biosimilars and Bioanalytical Methods
2021 - Springer Science+Business Media | European Journal of Clinical Pharmacology
Ivanka Savic, Balázs Gulyás, Maria Larsson, Per E. Roland,
Tópico(s): Advanced Chemical Sensor Technologies
2000 - Cell Press | Neuron
Krassimira Yoncheva, Borislav Tzankov, Yordan Yordanov, Ivanka Spassova, Daniela Kovacheva, Maria Frosini, Massimo Valoti, Virginia Tzankova,
The present study evaluated the impact of doxorubicin encapsulation in chitosan-alginate nanoparticles on its stability, cytotoxic potential in multidrug resistant lymphoma cells (L5178 MDR1) and toxicity in H9c2 cardioblasts. The results indicated that the encapsulation stabilized the drug against degradation due to its inner location in nanoparticles as suggested by thermogravimetric and X-ray diffraction analyses. Further, the encapsulated doxorubicin was significantly more cytotoxic to L5178 ...
Tópico(s): Chemotherapy-induced organ toxicity mitigation
2020 - Elsevier BV | Journal of Drug Delivery Science and Technology
Christophe Baudouin, David Galarreta, Ewa Mrukwa–Kominek, Daniel Böhringer, Vincenzo Maurino, Michel Guillon, Gemma Caterina Maria Rossi, Ivanka J. van der Meulen, Abayomi Ogundele, Marc Labétoulle,
Purpose To evaluate and compare the efficacy of a lipid-based lubricant eyedrop formulation (hydroxypropyl guar/propylene glycol/phospholipid [HPG/PG/PL]) with preservative-free saline for the treatment of dry eye. Methods This was a prospective, multicenter, randomized, single-masked, parallel-group phase 4 clinical study. Patients ≥18 years diagnosed with dry eye received 1 drop of saline 4 times daily (QID) for 15 days during a run-in phase, followed by randomization. Patients then instilled HPG/ ...
Tópico(s): Advancements in Transdermal Drug Delivery
2016 - SAGE Publishing | European Journal of Ophthalmology
Virginia Tzankova, Denitsa Aluani, Yordan Yordanov, Massimo Valoti, Maria Frosini, Ivanka Spassova, Daniela Kovacheva, Borislav Tzankov,
Lomefloxacin (LF) is interesting as a model molecule from a safety point of view because of its high potential for serious adverse drug effects (i.e. phototoxic reactions). In this study, MCM-41 mesoporous silica nanoparticles (MCM-41) were loaded with lomefloxacin, aiming to overcome the drug's intrinsic cytotoxicity. The good biocompatibility of the empty drug carrier (0.1–1.0 mg/ml) was established by the absence of red blood cell lysis (hemolysis assay). The cytotoxicity of empty MCM-41 and lomefloxacin- ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2019 - Taylor & Francis | Drug and Chemical Toxicology
Matteo Perra, Laura Fancello, Ines Castangia, Mohamad Allaw, Elvira Escribano-Ferrer, José Esteban Peris, Iris Usach, Maria Letizia Manca, Ivanka K. Koycheva, Milen I. Georgiev, Maria Manconi,
Culture of plant cells or tissues is a scalable, sustainable, and environmentally friendly approach to obtain extracts and secondary metabolites of uniform quality that can be continuously supplied in controlled conditions, independent of geographical and seasonal variations, environmental factors, and negative biological influences. In addition, tissues and cells can be extracted/obtained from the by-products of other industrial cultivations such as that of Lavandula angustifolia Miller (L. angustifolia), ...
Tópico(s): Essential Oils and Antimicrobial Activity
2022 - Multidisciplinary Digital Publishing Institute | Molecules
Ivanka Moneva, Maria Gramenova-Angelova, Mariyana Ivanova, Ivan Petrov,
Abstract The results of laboratory examinations of the ecological characteristics of diesel internal-combustion engine are represented in this article. The powerful, economical and ecological parameters of a diesel engine investigated in this article are presented by the speed characteristics of effective torque, injected fuel per cycle, and fuel and air consumption per hour, temperature, and smoke emissions of exhaust gases. On the basis of the experimental dependences a mathematical model is designed. ...
Tópico(s): Technical Engine Diagnostics and Monitoring
2020 - IOP Publishing | IOP Conference Series Materials Science and Engineering
Teodor Sandu, Anita-Laura Chiriac, Boyko Tsyntsarski, Ivanka Stoycheva, Simona Căprărescu, Celina Maria Damian, Tanţa-Verona Iordache, Delia Pătroi, Virgil Marinescu, Andrei Sârbu,
Abstract This paper describes the preparation of a new type of hybrid material suitable to be used for the amendment of wastewaters laden with Ni ions relying on two purification principles, mechanical and adsorption. The membranes were prepared using as first component copolymers of acrylonitrile with vinyl acetate, acrylic acid or methacrylic acid. The second component of the developed membranes consisted of powdered activated carbon (PAC), of natural or synthetic origin, used in a content of either ...
Tópico(s): Adsorption and biosorption for pollutant removal
2021 - Wiley | Polymer International
Ivanka K. Kavrakova, Maria J. Lyapova,
Tópico(s): Synthesis and Reactions of Organic Compounds
1996 - Taylor & Francis | Organic Preparations and Procedures International
Zoran Pavlović, Ivanka Miletić, Milica Zeković, Marina Nikolić, Maria Glibetić,
Research conducted during the 1980s demonstrated Se deficiency in humans. Increased inclusion of selenium in animal feeds started from the year 2000 onwards. The aim of this study was to estimate the effects of selenium inclusion in animal feeds on human selenium status and dietary habits of the Serbian population related to food of animal origin. Plasma selenium concentration in healthy adult volunteers, including residents of one of the regions with the lowest (Eastern Serbia, n = 60) and of one ...
Tópico(s): Heavy Metal Exposure and Toxicity
2018 - Multidisciplinary Digital Publishing Institute | Nutrients
Ivanka Netinger Grubeša, Berislav Marković, Martina Vračević, Maria Tunkiewicz, Imre Szenti, Ákos Kukovecz,
In this paper, the resistance to the freeze/thaw cycles for four groups of mortars (lime-LM, lime based-LBM, cement-CM, and aerated cement-ACM mortars) with different amount of mortar components within each group is quantified via a ratio of flexural/compressive strength after and before exposure to freeze/thaw cycles. Using a pore system obtained by three different methods (mercury intrusion porosimetry, X-ray micro-computed tomography analysis, and SEM (Scanning Electron Microscopy) analysis), an ...
Tópico(s): Innovative concrete reinforcement materials
2019 - Multidisciplinary Digital Publishing Institute | Materials
Ivanka K. Kavrakova, Maria J. Lyapova,
Conversion of the easily available trans -2-oxoimidazolidine-4-carboxylic acid 1 to the corresponding imidazolidines 8 gives after one-step oxidation and ring cleavage the diamino acid 2 in high yield. The difference in the trans -vicinal couplings for the hydrogen-bonded and nonbonded compounds suggests different ring geometry as a result of the balancing effect of the N 1 substituent on the "allylic strain".
Tópico(s): Catalytic C–H Functionalization Methods
2000 - Wiley-VCH | Collection of Czechoslovak Chemical Communications
Dessislava Jereva, Petko Alov, Ivanka Tsakovska, Maria Angelova, Vassia Atanassova, Peter Vassilev, Nikolay Ikonomov, Krassimir Atanassov, Ilza Pajeva, Tania Pencheva,
(1) Background: In silico approaches to rational drug design are among the fastest evolving ones. Depending on the available structural information for the biomacromolecule and the small molecule, the in silico methods are classified as ligand- and structure-based. The latter predict ligand–receptor binding using 3D structures of both molecules, whose computational simulation is referred to as molecular docking. It aims at estimating the binding affinity (approximated by scoring function) and the ...
Tópico(s): Statistical and Computational Modeling
2022 - Multidisciplinary Digital Publishing Institute | Mathematics
Michelle Cespedes, Moupali Das, Jenna Yager, Maria Prins, Ivanka Krznaric, Jan de Jong, Deqing Xiao, Yongwu Shao, Pamela Wong, Alexander Kintu, Christoph C Carter, Elske Hoornenborg, Peter Ruane, John Phoenix, Islam R. Younis, Jason Halperin,
Purpose: Transgender women are disproportionately affected by HIV and are underutilizing preexposure prophylaxis (PrEP). The lower uptake of PrEP by transgender women may be, in part, owing to the perception that taking PrEP may lower the efficacy of gender-affirming hormone therapy (GAHT) or to provider concerns that GAHT may lower the efficacy of PrEP. Methods: DISCOVER was a randomized, double-blind, noninferiority trial comparing emtricitabine (FTC, F) and tenofovir alafenamide (F/TAF) versus emtricitabine ...
Tópico(s): HIV/AIDS drug development and treatment
2022 - Mary Ann Liebert, Inc. | Transgender Health
Jie Xia, Anne M. Noronha, Ivanka Toudjarska, Feng Li, Akin Akinc, Ravi Braich, Maria Frank-Kamenetsky, Kallanthottathil G. Rajeev, Martin Egli, Muthiah Manoharan,
Recently, chemically synthesized short interfering RNA (siRNA) duplexes have been used with success for gene silencing. Chemical modification is desired for therapeutic applications to improve biostability and pharmacokinetic properties; chemical modification may also provide insight into the mechanism of silencing. siRNA duplexes containing the 2,4-difluorotoluyl ribonucleoside (rF) were synthesized to evaluate the effect of noncanonical nucleoside mimetics on RNA interference. 5′-Modification of ...
Tópico(s): DNA and Nucleic Acid Chemistry
2006 - American Chemical Society | ACS Chemical Biology
Boris P. Atanasov, Maria I. Mitovska, Ivanka Mancheva, Ganka P. Kossekova, B. Tchorbanov, Petia Christova, Kirana I. Dancheva,
The preparation, purification and characterization of the three singly, three doubly and one triply substituted derivatives of cytochrome c modified by pyridoxal phosphate (PLP) at lysine residues are reported. The PLP positions in PLP derivatives were determined by the amino acid analysis and sequence of PLP peptides. The results identified the lysine at position 86 in one of the singly substituted, lysine 79 in the other singly substituted and lysines 86 and 79 in the third doubly substituted cytochrome ...
Tópico(s): Mass Spectrometry Techniques and Applications
1984 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Bioenergetics
Martin Tsvetkov, Elzhana Encheva, Stefani Petrova, Ivanka Spassova, Maria Milanova,
The synthesis of orthoferrites of the type La1−xCexFeO3+x/2, x = 0.00, 0.01, 0.03, 0.05, and 0.07, by applying a simple and effective mechanochemical transformation from the constituent oxides is presented. Physicochemical methods such as powder X-ray diffraction (XRD), transmission electron microscopy (TEM), UV–Vis spectroscopy, and Brunauer–Emmett–Teller (BET) adsorption were applied to gain information about the effect of Ce4+ content on the structural, textural, and optical properties of the samples. ...
Tópico(s): Layered Double Hydroxides Synthesis and Applications
2023 - Multidisciplinary Digital Publishing Institute | Crystals
Kate Renshall, Paul Rhodes, Jenny Brown, Michelle K. Donnelly, Holly Donnelly, Megan Gosbee, Melanie Mence, Maria Ivanka Milić, Katie Treanor, Dean Wainer,
Tópico(s): Child Therapy and Development
2013 - Springer Science+Business Media | Contemporary Family Therapy
Soultana-Maria Valamoti, Elena Marinova, Andreas G. Heiss, Ivanka Hristova, Chryssa Petridou, T. I. Popova, Stavroula Michou, Lambrini Papadopoulou, Panagiotis Chrysostomou, Pascal Darcque, Dimitrios Grammenos, Stanislav Iliev, Stavros Kotsos, Chaido Koukouli-Chrysanthaki, Krassimir Leshtakov, Dimitria Malamidou, Nikos Merousis, Vassil Nikolov, Krassimir Nikov, Κrastina Panayotova, Aikaterini Papanthimou, Hristo Popov, Liana Stefani, Zoï Tsirtsoni, Tatjana Kanceva Ruseva,
This paper addresses for the first time a large body of archaeobotanical data from prehistoric Southeastern Europe, mostly published for the first time, that correspond to cereal food preparations. The evidence presented here comes from 20 sites situated in Greece and Bulgaria, spanning the Early Neolithic through to the Iron Age (7th millennium B.C.-1st millennium B.C.). The remains correspond to cereal fragments or agglomerations of fragments that resulted from ancient food preparation steps such ...
Tópico(s): Isotope Analysis in Ecology
2019 - Elsevier BV | Journal of Archaeological Science
Raina Gergova, Virna-Maria Tsitou, Ivanka Gergova, Adile Muhtarova, Ivan Mitov,
Background: Infections due to methicillin resistant Staphylococcus aureus (MRSA) which is the most virulent species among the staphylococci have become a global health challenge. The aim of this study was to assess the correlation of genes encoding virulence and methicillin resistance in invasive and non-invasive isolates from inpatients/outpatients with staphylococcal infections in Sofia, Bulgaria.Materials and methods: Non-duplicate S. aureus isolates were recovered from clinical samples obtained ...
Tópico(s): Microbial Metabolism and Applications
2019 - African Journals OnLine | African Journal of Clinical and Experimental Microbiology
Anamarija Đuras, Valentina Cesar Kocijan, Anamarija Rade, Renata Lipovec, Ivanka Ostroški, Vanja Radišić Biljak, Ana-Maria Šimundić,
Objectives The body of literature varies significantly regarding serum and urine osmolality stability. Therefore, our aim was to investigate the stability of serum and urine osmolality at different temperatures (room temperature (RT) 4–8 °C, −20 °C) and time conditions (8 h, 24 h, 1 month).Methods The stability study was conducted following the CRESS guidelines, including 40 serum and urine samples. Samples were aliquoted into three aliquots and stored as follows: primary tube stored at RT for 8 h; two ...
Tópico(s): Meta-analysis and systematic reviews
2022 - Taylor & Francis | Scandinavian Journal of Clinical and Laboratory Investigation
Iliya Zhelev, Pavel Merdzhanov, Maria Angelova‐Romova, М. Zlatanov, Ginka Antova, Ivanka Dimitrova‐Dyulgerova, Albena Stoyanova,
Zhelev, I., P. MerdZhanov, М. AngelovA-RomovA, m. ZlAtAnov, g. AntovA, I. DImItRovADyulgeRovA and A. StoyAnovA, 2014. lipid composition of Carduus thoermeri Weinm., Onopordum acanthium l. and Silybum marianum l., growing in Bulgaria. Bulg. J. Agric. Sci., 20: 622-627 Seed oil chemical composition of wild growing Carduus thoermeri Weinm., Onopordum acanthium l. and Silybum marianum l. were studied for the first time in Bulgaria, by using gC, HPlC, tlC and spectrophotometrical methods. the major components ...
Tópico(s): Silymarin and Mushroom Poisoning
2014 - Agricultural Academy of Bulgaria | Bulgarian Journal of Agricultural Science
Pedro Cahn, Juan Sierra Madero, José Ramón Arribas, Andrea Antinori, Roberto Ortiz, Amanda E. Clarke, Chien‐Ching Hung, Jürgen K. Rockstroh, Pierre‐Marie Girard, Jörg Sievers, Choy Man, Alexander Currie, Mark Underwood, Allan R. Tenorio, Keith A. Pappa, Brian Wynne, Anna Fettiplace, Martin Gartland, Michael Aboud, Kimberly Y. Smith, Lidia Isabel Cassetti, Daniel David, Laura Figueras, Marcelo H. Losso, Gustavo Lopardo, Sergio Lupo, Norma Porteiro, Marisa Sánchez, Mark Bloch, D. James Cooper, Robert Finlayson, Anthony D. Kelleher, Kenneth Koh, David John Lewis, James McMahon, Richard Moore, Norman Roth, Matt Shields, Stéphane De Wit, Éric Florence, Jean‐Christophe Goffard, Rémy Demeester, Patrick Lacor, Bernard E. Van Beers, Linos Vandekerckhove, Jonathan B. Angel, Jean‐Guy Baril, Brian Conway, Alexandra de Pokomandy, Jason Szabo, Sharon Walmsley, Olivier Bouchaud, Christian Chidiac, Pierre Delobel, Cécile Goujard, Christine Katlama, Jean‐Michel Molina, Gilles Pialoux, Patrick Philibert, Johannes R. Bogner, Stefan Esser, Ivanka Krznaric, Clara Lehmann, Christoph D. Spinner, Hans‐Jürgen Stellbrink, Christoph Stephan, Albrecht Stoehr, Enrico Barchi, Pietro Caramello, Francesco Castelli, Anna Maria Cattelan, Antonella D'Arminio Monforte, Antonio Di Biagio, Giovanni Di Perri, Andrea Gori, Franco Maggiolo, Barbara Menzaghi, Guglielmo Marco Migliorino, Cristina Mussini, Giovanni Penco, Massimo Puoti, Giuliano Rizzardini, Roberto Gulminetti, Adriano Lazzarin, Tiziano Quirino, Laura Sighinolfi, Pierluigi Viale, Gerardo Amaya Tapia, Jaime Andrade‐Villanueva, Enrique R Granados Reyes, Alma Perez Rios, Mario Santoscoy Gomez, Jan Den Hollander, Bart Rijnders, José A. Hidalgo, Luis Hercilla Vásquez, Luis Ricardo Illescas, Anita Olczak, Kamal Mansinho, Patrícia Pacheco, Eugénio Teófilo, José Saraiva da Cunha, Rui Sarmento e Castro, Rosário Serrão, Manuela Arbune, Cristian Jianu, Anca Oprea, Liliana Preoțescu, Liviu-Jany Prisacariu, Elena Belonosova, Olga Borodkina, Oxana Chernova, Natalia Gankina, Svetlana Kizhlo, Valeriy Viktorovich Kulagin, Nadezhda Kurina, Ф. И. Нагимова, Vadim Pokrovsky, E. P. Ryamova, Evgeny Voronin, A. N. Yakovlev, Richard Kaplan, Sun Hee Lee, Shin‐Woo Kim, Sangil Kim, Woo Joo Kim, Antonio Antela Lopez, José L. Casado, Manuel Angel Castano Carracedo, Ignacio de los Santos, Vicente Estrada Pérez, Vicenç Falcó Ferrer, Luís Force, Maria Jose Galinda Puerto, Miguel García Deltoro, Josep M. Gatell, Miguel A Goenaga Sanchez, Ana González-Cordón, Hernando Knobel, Juan Carlos López Bernaldo de Quirós, Juan E Losa Garcia, Mar Masiá, Marta Montero, Antonio Ocampo Hermida, Juan Pasquau Liaño, Joaquin Portilla Sogorb, Federico Pulido, Antonio Rivera Roman, Jose Ramon Santos Fernandez, Rafael Torres Perea, Jesús Troya, Pompeyo Viciana Fernandez, Alexandra Calmy, Christoph Hauser, Jan Fehr, Shu‐Hsing Cheng, Wen‐Chien Ko, Hsi-Hsun Lin, Po‐Liang Lu, Yu‐Ting Tseng, Ning‐Chi Wang, Wing-Wai Wong, Chia‐Jui Yang, Roberto C. Arduino, Paul Benson, Mezgebe Berhe, Fritz Bredeek, Cynthia Brinson, Thomas L. Campbell, Gordon Crofoot, Douglas Cunningham, Edwin DeJesus, Robin Dretler, Joseph J. Eron, Kenneth H. Fife, Carl J. Fichtenbaum, Jason Flamm, Deborah Goldstein, Samir K. Gupta, Debbie Hagins, Margaret Hoffman-Terry, Dushyantha Jayaweera, Clifford Kinder, Daniel B. Klein, Cheryl McDonald, Anthony Mills, Ronald Nahass, Olayemi Osiyemi, Edgar T. Overton, David Parks, David James Prelutsky, Moti Ramgopal, Shannon Schrader, Beverly E. Sha, Gary L. Simon, James J. Sims, Daniel J. Skiest, Jihad Slim, Karen T. Tashima, Blair Thedinger, Brian Gazzard, Julie Fox, Margaret Johnson, Stephen Kegg, Saye Khoo, C Mazhude, Chloe Orkin, Gabriel Schembri, Andrew Ustianowski,
Summary Background Effective two-drug regimens could decrease long-term drug exposure and toxicity with HIV-1 antiretroviral therapy (ART). We therefore aimed to evaluate the efficacy and safety of a two-drug regimen compared with a three-drug regimen for the treatment of HIV-1 infection in ART-naive adults. Methods We conducted two identically designed, multicentre, double-blind, randomised, non-inferiority, phase 3 trials: GEMINI-1 and GEMINI-2. Both studies were done at 192 centres in 21 countries. We ...
Tópico(s): HIV-related health complications and treatments
2018 - Elsevier BV | The Lancet
Irina Lazarkevich, Stephan Engıbarov, Simona Mitova, Emiliya Vacheva, Steliyana Popova, Nikola Stanchev, Rumyana Еneva, Yana Gocheva, Ivanka Boyadzhieva, Maria Gerginova,
Studies on the gut microbiome of free-living reptiles in Europe are generally fragmentary and still missing in Bulgaria. We aimed to identify and compare the fecal microbiota profiles of five syntopic lizard species from three families: the European green lizard (Lacerta viridis), the common wall lizard (Podarcis muralis), the meadow lizard (Darevskia praticola) (Lacertidae), the European snake-eyed skink (Ablepharus kitaibelii) (Scincidae), and the European slow worm (Anguis fragilis) (Anguidae), which ...
Tópico(s): Reproductive tract infections research
2024 - | Applied Microbiology
Ana‐Maria Forsea, Ivanka Kovalyshyn, Stephen W. Dusza, Allan C. Halpern,
BACKGROUND The general public and health professionals are increasingly choosing the Internet to access skin cancer prevention information. OBJECTIVES To identify the optimal mechanism for finding skin cancer educational resources through the Internet and to characterize the resources currently available on-line. METHODS A survey of experts involved in skin cancer prevention, followed by standardized searches through popular general Internet search engines using a list of 10 terms relevant to skin ...
Tópico(s): Cutaneous Melanoma Detection and Management
2010 - Lippincott Williams & Wilkins | Dermatologic Surgery
Martin Tzvetkov, Maria Milanova, Zara Cherkezova‐Zheleva, Ivanka Spassova, E. Valcheva, Joana Zaharieva, Ivan Mitov,
A combination of thermal and mechanical (high energy ball milling) treatment was applied in an attempt to obtain polycrystalline mixed metal binary and ternary oxides of the type Co x Zn 1-x Fe 2 O 4 (x=0; 0.25; 0.5; 0.75; 1). The synthetic procedure used successfully produced single-phased, homogeneous ZnFe 2 O 4 , CoFe 2 O 4 , and Co 0.75 Zn 0.25 Fe 2 O 4 , as well as mixed oxides, whose composition depended both on the duration of the high energy ball milling and the ratio Zn(II)/Co(II). The formation ...
Tópico(s): Copper-based nanomaterials and applications
2017 - Slovenian Chemical Society | Acta chimica slovenica