Nicola Baldini, Katia Scotlandi, Massimo Serra, Katsuyuki Kusuzaki, Toshiharu Shikita, Maria Cristina Manara, Daniela Maurici, Mario Campanacci,
Tópico(s): HER2/EGFR in Cancer Research
1992 - Springer Science+Business Media | Journal of Cancer Research and Clinical Oncology
Katia Scotlandi, Massimo Serra, Maria Cristina Manara, Daniela Maurici, Stefania Benini, Giuseppe Nini, Mario Campanacci, Nicola Baldini,
Background. The availability of Ki-67 monoclonal antibody has opened new possibilities for an extensive analysis of cell kinetics in human neoplasms. Ki-67 antibody reveals a nuclear antigen that is expressed in proliferating but not in quiescent cells. Although the reliability of Ki-67 immunostaining has been evaluated in different tumor types, little information has been reported on bone neoplasms. Methods. Cell proliferation, as determined by Ki-67 expression, was measured by immunofluorescence ...
Tópico(s): Lymphoma Diagnosis and Treatment
1995 - Wiley | Cancer
Massimo Serra, Katia Scotlandi, Maria Cristina Manara, Daniela Maurici, Stefania Benini, Manuela Sarti, Mario Campanacci, Nicola Baldini,
Current treatment of high-grade osteosarcoma combines surgical removal of the lesion with chemotherapy. In this study we evaluated whether the expression of P-glycoprotein, a protein closely associated with multidrug resistance, may be helpful in identifying the patients whose tumours will be further resistant to specific agents. By using multidrug-resistant osteosarcoma cell lines as standards, the expression of P-glycoprotein was evaluated in 105 cases of primary and metastatic osteosarcoma by ...
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
1995 - Elsevier BV | European Journal of Cancer
Nicola Baldini, Katia Scotlandi, Giovanni Barbanti Bròdano, Maria Cristina Manara, Daniela Maurici, Gaetano Bacci, Franco Bertoni, Piero Picci, S. Sottili, Mario Campanacci, Massimo Serra,
Increased levels of P-glycoprotein occur in some osteosarcomas. In this study we determined the relation between P-glycoprotein status and outcome in patients with high-grade osteosarcoma.
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
1995 - Massachusetts Medical Society | New England Journal of Medicine
Maria Cristina Manara, Katia Scotlandi, Massimo Serra, Daniela Maurici, Manuela Sarti, Mario Campanacci, Nicola Baldini,
The Colony-Stimulating Factors (CSFs) are undergoing clinical trials for their ability to stimulate the regeneration of bone marrow in patients receiving anticancer chemotherapy. However, the reported effects on the growth of tumor cell lines of different derivations, including osteosarcoma, raise the possibility that the use of these cytokines may induce proliferative effects also in residual tumor cells. In this study, we have used a panel of 12 human osteosarcoma (2 cell lines and 10 primary cultures) ...
Tópico(s): Proteoglycans and glycosaminoglycans research
1995 - Spandidos Publishing | International Journal of Oncology
Katia Scotlandi, Maria Cristina Manara, Massimo Serra, Stefania Benini, Daniela Maurici, Antonella Caputo, Carla De Giovanni, Pier‐Luigi Lollini, Patrizia Nanni, Piero Picci, Mario Campanacci, Nicola Baldini,
The relationship between P-glycoprotein expression and malignancy is controversial. We have recently found that, in osteosarcoma, multidrug resistance (MDR) is associated with a less aggressive behavior, both in vitro and in clinical settings. In this study, we evaluated whether P-glycoprotein overexpression has a cause-effect relationship with the reduced metastatic potential of MDR cells, or rather reflects a more complex phenotype. MDR1 gene-transfected osteosarcoma cell clones, showing different ...
Tópico(s): Nanoparticle-Based Drug Delivery
1999 - Springer Nature | Oncogene
Maurici Luzia Charnevski Del Monego, Patrícia Ramos, Mário V. Neves,
The main purpose of this study was to examine the applicability of geostatistical modeling to obtain valuable information for assessing the environmental impact of sewage outfall discharges. The data set used was obtained in a monitoring campaign to S. Jacinto outfall, located off the Portuguese west coast near Aveiro region, using an AUV. The Matheron's classical estimator was used the compute the experimental semivariogram, which was fitted to three theoretical models: spherical, exponential and ...
Tópico(s): Remote Sensing and LiDAR Applications
2010 - Springer Nature (Netherlands) | Quantitative geology and geostatistics
Produção Nacional
Maurici Luzia Charnevski Del Monego, Patrícia Ramos, Mário V. Neves,
O principal objetivo deste estudo foi analisar a aplicabilidade da modelagem geoestatística para a avaliação do impacto ambiental de descargas de águas residuais provenientes de
Tópico(s): Geography and Environmental Studies
2010 - Brazilian Association of Water Resources | RBRH
Produção Nacional
Rosemeri Maurici da Silva, Mário Sérgio Soares de Azeredo Coutinho, Márcia Margaret Menezes Pizzichinni,
O uso da broncofibroscopia com realizacao de lavado broncoalveolar, escovado bronquico e biopsia pulmonar transbronquica destaca-se como metodo util no diagnostico das afeccoes pulmonares em pacientes infectados com o virus da imunodeficiencia humana (HIV). Contudo, os dados referentes a acuracia dessas tecnicas sao conflitantes. A fim de estimar a sensibilidade do lavado broncoalveolar, escovado bronquico e biopsia pulmonar transbronquica no diagnostico de afeccoes pulmonares em pacientes infectados ...
Tópico(s): Tuberculosis Research and Epidemiology
1999 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal de Pneumologia
Produção Nacional
Revisado por pares
Forest W. Arnold, Gustavo Lopardo, Timothy L. Wiemken, Robert Kelley, Paula Peyrani, William A. Mattingly, Charles Feldman, Martin Gnoni, Rosemeri Maurici, Julio A. Ramírez, Forest W. Arnold, Paula Peyrani, Julio A. Ramírez, Kwabena Ayesu, Thomas M. File, Steven D. Burdette, Stephen P. Blatt, Marcos I. Restrepo, José Bordón, Peter Groß, Daniel M. Musher, Thomas J. Marrie, Karl Heinz Weiss, Jorge Roig, H. Lode, Tobias Welte, Stefano Aliberti, Francesco Blasi, Roberto Cosentini, Delfino Legnani, Fabio Franzetti, Nicola Montano, Giulia Cervi, Paolo Giorgi Rossi, Antonio Voza, Belinda Ostrowsky, Alberto Pesci, Stefano Nava, Pierluigi Viale, Vanni Galavatti, Aruj Patricia, Carlos Dimas, Roberto Piro, Claudio Viscoli, Antoní Torres, Vincenzo Valenti, Daniel Portela Ojales, María Bodí, José Antonio Porras, Jordi Rello, Rosario Menéndez, Daiana Stolz, Philipp Schüetz, Sebastian Haubitz, James D. Chalmers, Tom Fardon, Guillermo Benchetrit, Eduardo Rodrı́guez, Jorge Corral, José Pablo Miramontes‐González, Lautaro De Vedia, Gustavo Lopardo, Carlos M. Luna, Jorge Martínez, Lucía Marzoratti, Maria Soledad Rodrı́guez González, Alejandro J. Videla, Federico Saavedra, Horacio Pérez López, Martin Gnoni, José Pablo Miramontes‐González, Carlos Victorio, Fernando Riera, Patricio Jiménez, Patricia Fernández, Maria Parada, Alejandro Díaz Fuenzalida, Raúl Riquelme, Manuel Barros, Juan Manuel Rocha Luna, Ivan Toala, Guillermo Arbo Oze de Morvil, Ricardo Fernández, Gonzalo Aiello, Pablo Alvarez, Ana Soca, Federico Arteta, J. Fernández Delgado, Gur Levy, Ludwig Rivero, Benito Rodrı́guez, Mario Perez Mirabal, Marilyn Mateo, Myrna Mendoza, Charles Feldman,
Community-acquired pneumonia (CAP) has a potential complication of bacteremia. The objective of this study was to define the clinical outcomes of patients with CAP and bacteremia treated with and without a macrolide.Secondary analysis of the Community-Acquired Pneumonia Organization database of hospitalized patients with CAP. Patients with a positive blood culture were categorized based on the presence or absence of a macrolide in their initial antimicrobial regimen, and severity of their CAP. Outcomes ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2018 - Elsevier BV | Respiratory Medicine
Elisa Aiassa, Laura Martino, Fulvio Barizzone, Laura Ciccolallo, Ana Caroline Falcão Garcia, Marios Georgiadis, Irene Muñoz Guajardo, Daniela Tomčíková, Jan Alexander, Paolo Calistri, Ursula Gundert‐Remy, Andrew Hart, L.A.P. Hoogenboom, Antoine Messéan, Androniki Naska, María Navajas Navarro, Birgit Noerrung, Colin Ockleford, Robert John Wallace, Maged Younes, Blaize Abuntori, Fernando Álvarez, Monica Aryeetey, Francesca Baldinelli, Federica Barrucci, Andrea Baù, Marco Binaglia, Alessandro Broglia, Anna Federica Castoldi, Eugen H. Christoph, Agnès de Sesmaisons‐Lecarré, Nikolaos Georgiadis, Andrea Gervelmeyer, Frédérique Istace, Gloria López‐Gálvez, Paola Manini, Daniela Maurici, Caroline Merten, Winy Messens, Olaf Mosbach‐Schulz, Claudio Putzu, Luisa Ramos Bordajandi, Camilla Smeraldi, Manuela Tiramani, Silvia Valtueña Martínez, Vos Sybren, Amy Hardy, Marta Hugas, Juliane Kleiner, Guilhem De Seze, Hans Verhagen, Didier Verloo,
In 2014, the European Food Safety Authority (EFSA) started the PROMETHEUS (PROmoting METHods for Evidence Use in Scientific assessments) project to improve further and increase the consistency of the methods it uses in its scientific assessments. The project defined a set of principles for the scientific assessment process and a 4-step approach (plan/carry out/verify/report) for their fulfilment, which was tested in ten case studies, one from each EFSA panel. The present report describes the benefits, ...
Tópico(s): Pesticide Residue Analysis and Safety
2018 - European Food Safety Authority | EFSA Supporting Publications
Claudia Bolognesi, Emanuela Corsini, Riccardo Crebelli, Rex FitzGerald, Claude Lambré, Francesca Romana Mancini, Marcel Mengelers, Gilles Rivière, Emanuela Testai, Detlef Wölfle, Chantra Eskes, Marios Georgiadis, Irene Muñoz Guajardo, Katharina Volk, Laurence Castle,
... E, van Benthem J, Carfì M, Georgiadis N, Maurici D, Parra Morte J and Schlatter J, 2017a. ... Nielsen E, Solecki R, Carfı M, Martino C, Maurici D, Parra Morte J and Schlatter J, 2019b. ... Nielsen E, Vleminckx C, Carfì M, Martino C, Maurici D, Parra Morte J, Rossi A and Benford ...
Tópico(s): Agricultural safety and regulations
2022 - European Food Safety Authority | EFSA Supporting Publications