Haran Burri, Aurelio Quesada, Renato Pietro Ricci, Giuseppe Boriani, Mario Davinelli, Stefano Favale, Antoine Da Costa, Josef Kautzner, Raymond Moser, Xavier Navarro, Massimo Santini,
With the advent of remote monitoring, current models of implantable cardioverter defibrillators (ICDs) have the possibility of sending automatic alert messages that allow early diagnosis of events such as lung fluid overload, atrial fibrillation and device integrity issues. Timely treatment of these events has the potential to improve patient outcome, but this has not as yet been proven. The MORE-CARE study is a multicenter randomized controlled trial evaluating the efficacy of advanced device diagnostics ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2010 - Elsevier BV | American Heart Journal
Elisa Costa, Mario Rodríguez-Domínguez, María Ángeles Clari, Estela Giménez, Juan Carlos Galán, David Navarro,
The performance of the CLART® PneumoVir system with that of the Luminex xTAG RVP Fast v1 assay for detection of most common respiratory viruses in upper and lower tract respiratory specimens (n = 183) from unique patients with influenza-like syndrome or lower tract respiratory infection. Nested PCR coupled to automated sequencing was used for resolution of discrepancies. Fully concordant results were obtained for a total of 122 specimens, whereas 56 specimens gave partially (n = 21) or fully discordant ( ...
Tópico(s): Viral gastroenteritis research and epidemiology
2015 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Produção Nacional
Revisado por pares
Renato Allan Navarro Andrade, Stéfani Iury E. Andrade, Valdomiro Lacerda Martins, Pablo Nogueira Teles Moreira, Daniel Jackson Estevam da Costa, Wellington da Silva Lyra, Mário César Ugulino de Araújo,
The traditional flow chemiluminescence (CL) systems typically use flow cells in spiral shape mounted in front of a photomultiplier tube (PMT). The sample is transported by using carrier fluids, undergoes dispersion, and mixes with reagents and CL reaction occurs before reaching the flow cell. As a consequence, the maximum of the chemiluminescence intensity is not exploited and the sensitivity is significantly diminished. In this work, these drawbacks were overcome by using a flow–batch approach and ...
Tópico(s): Microfluidic and Capillary Electrophoresis Applications
2012 - Elsevier BV | Microchemical Journal
Produção Nacional
Revisado por pares
Paulo Milet‐Pinheiro, Arthur Domingos‐Melo, João B. Olivera, Nayara Silva Lins de Albuquerque, Ana Carolina Galindo da Costa, Sinzinando Albuquerque‐Lima, Marcelo Silva, Daniela Maria do Amaral Ferraz Navarro, Artur Campos Dália Maia, Lise‐Lotte Gundersen, Mario Schubert, Stefan Dötterl, Isabel Cristina Machado,
Perfume flowers (sensu Vogel1) produce intense scents that function both as attractants and as the sole rewards for pollinators. The scent is collected exclusively by male euglossine bees and used during pre-mating behavior.2-5 Perfume flowers have evolved independently in 15 angiosperm families, with over 1,000 reported species across the Neotropical region.6 Members of Cryptanthus (Bromeliaceae) represent a puzzling exception among perfume flowers, as flowers produce nectar and do not emit a noticeable ...
Tópico(s): Plant Diversity and Evolution
2020 - Elsevier BV | Current Biology
Produção Nacional
Revisado por pares
Emili Bortolon dos Santos, Mario Arthur Favretto, Samuel Geremias dos Santos Costa, Mário Antônio Navarro-Silva,
In this study, a total of 4146 culicids collected in an Atlantic Forest area in Paraná state, southern Brazil were examined for the presence of mites. Forty larval Parasitengone mites (Arrenurus spp., Arrenuridae; Durenia spp., Trombellidae; Microtrombidium spp., Microtrombidiidae) parasitized 25 specimens of mosquitoes, with the intensity varying from one to nine mites attached. Most mites were found on Aedes serratus/nubilus, Culex vomerifer, Cx. pedroi and Cx. sacchettae. The overall percentage ...
Tópico(s): Bird parasitology and diseases
2016 - Springer Science+Business Media | Experimental and Applied Acarology
Rafael San Juan, Begoña de Dios, David Navarro, Ana García‐Reyne, Carlos Lumbreras, Dayana Bravo, Elisa Costa, José María Morales, Amado Andrés, Carlos Jiménez‐Romero, Juan F. Delgado, Mario Fernández‐Ruiz, Francisco López‐Medrano, José María Aguado,
Epstein-Barr virus (EBV) DNAemia (EBVd) may be a surrogate marker of the net state of immunosuppression after solid organ transplantation (SOT).A sample of 81 SOT recipients (53 renal, 21 liver, and 7 cardiac) from our institution (2003-2004) surviving more than 180 days was analyzed. EBVd was monitored in whole blood within the first 6 months using a real-time polymerase chain reaction assay. Using a Cox proportional hazards model, duration and magnitude of EBVd were assessed as potential surrogate ...
Tópico(s): Renal Transplantation Outcomes and Treatments
2012 - Wolters Kluwer | Transplantation
Produção Nacional
Revisado por pares
Emmanoel Vilaça Costa, Thanany Brasil da Silva, Leociley Rocha Alencar Menezes, Luis Henrique Gonzaga Ribeiro, Fernanda Ramos Gadelha, João Ernesto de Carvalho, Ligia Souza, Mário Antônio Navarro-Silva, Carlos Alberto Theodoro Siqueira, Marcos José Salvador,
Abstract The essential oil from the leaves of Xylopia laevigata was obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry (GC/MS) and GC/flame ionization detector (GC/FID). Thirty-six compounds representing 97.48% of the crude essential oil were identified. The major compounds identified were -muurolene (17.99%), -cadinene (13.45%), germacrene D (9.09%), bicyclogermacrene (7.00%), -copaene (5.98%), and (E)-caryophyllene (5.43%). The biological activities of the essential oil against ...
Tópico(s): Insect Pest Control Strategies
2012 - Taylor & Francis | Journal of Essential Oil Research
Produção Nacional
Sullamy Dayse Gomes Aciole, Carla Fernanda Piccoli, Jonny E. Duque, Emmanoel Vilaça Costa, Mário Antônio Navarro-Silva, Francisco A. Marques, Beatriz H. L. N. Sales Maia, Maria Lúcia B. Pinheiro, María Teresa Rebelo,
The products of vegetal origin were assessed for bioactive substances to reduce reliance on organophosphate and pyrethroid insecticides, to which insect populations have become resistant. For this reason the aim of this study was to assess whether the essential oils of Guatteria hispida, G. blepharophylla and G. friesiana have insecticidal effect against A. aegypti under laboratory conditions. Essential oils were extracted through hydrodistillation using a modified Clevenger apparatus and analyzed ...
Tópico(s): Mosquito-borne diseases and control
2011 - | Revista Colombiana de Entomología
Manuel D. Gahete, David Rincon Fernandez Pacheco, Mario Durán‐Prado, Marta Hergueta‐Redondo, Alejandro Ibáñez‐Costa, Alejandro Rojo‐Sebastián, Francisco Gracia‐Navarro, Michael D. Culler, Oriol Casanovas, Gema Moreno‐Bueno, Raúl M. Luque, Justo P. Castaño,
The truncated somatostatin receptor sst5TMD4 is associated with poor prognosis in breast cancer and increases breast cancer cell malignancy. Here, we examined the cellular/molecular mechanisms underlying this association, aiming to identify new molecular tools to improve diagnosis, prognosis or therapy. A gene expression array comparing sst5TMD4 stably-transfected MCF-7 cells and their controls (empty-plasmid) revealed the existence of profound alterations in the expression of genes involved in key ...
Tópico(s): Angiogenesis and VEGF in Cancer
2016 - Impact Journals LLC | Oncotarget
Produção Nacional
Magda Clara Vieira da Costa-Ribeiro, Ana Cristina Tissot, Mário Antônio Navarro-Silva,
Seazonal distribution of Culex (Culex) eduardoi Casal & Garcia (Diptera, Culicidae) in artificial receptac1es in disturbed patch offorest degraded in urban area of Curitiba, Paraná, Brazil.The utilization of artificial receptac1es to oviposition by mosquitoes in forest environment may indicate a sinantropic tendency or behaviour.Our data revealed that tires were as the most acceptable breeding for Culex (Culex) eduardoi Casal & Garcia 1968.The population density of tbis species was higher and summer seasons.
Tópico(s): Zoonotic diseases and public health
2002 - Sociedade Brasileira de Zoologia | Revista Brasileira de Zoologia
Simone Agostini, Roberta Mancuso, Andrea Saul Costa, Lorenzo Agostino Citterio, Franca Rosa Guerini, Mario Meloni, Jorge Navarro, Mario Clerici,
The etiology of Parkinson's disease (PD), a progressive nervous system disorder that affects movement, is still unknown; both genetic and environmental factor are believed to be involved in onset of the disease and its development. Herpes simplex virus type 1 (HSV-1), in particular, is suspected to have a role in PD. Paired Immunoglobulin-like type 2 receptor alpha (PILRA) is an inhibitory receptor that down-regulates inflammation and is expressed on innate immune cells. The
Tópico(s): Herpesvirus Infections and Treatments
2021 - Multidisciplinary Digital Publishing Institute | Vaccines
Produção Nacional
Revisado por pares
Mário Luis Ferreira da Silva, Saulo de Freitas Gonçalves, Matheus Carvalho Barbosa Costa, Rudolf Huebner, Túlio Pinho Navarro,
The development of stent-grafts for the total repair of aneurysms in the aortic arch is still a technical challenge due mainly to the anatomical complexity of this region. Research performed here structurally evaluated a modular branched stent-graft for aneurysms encompassing all zones of the aortic arch by means of numerical simulations using fluid–structure interaction. The geometric domain obtained by means of computed tomography was subjected to physiological boundary conditions. The blood was ...
Tópico(s): Elasticity and Material Modeling
2023 - Elsevier BV | Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
Mario Pino, R. Ximena Navarro,
El sitio arqueologico Chan-Chan 18 (39°30'S/73°15'W) corresponde a un asentamiento costero complejo del Arcaico Medio. En el se reconocen dos fases de ocupacion separadas por un hiatus, datadas entre 5.730-6.130 y 6.250-6.420 anos cal. AP, respectivamente. Analisis estratigraficos y granulometricos interpretados mediante analisis multivariados, que incluyen muestras actuales de playas y dunas, han permitido reconocer que la ocupacion mas antigua del sitio se asento al borde de la berma de una paleoplaya. ...
Tópico(s): Geological and Tectonic Studies in Latin America
2005 - National Geology and Mining Service | Revista geológica de Chile
Rui Barata, Bernardo Marques da Costa, David Navarro, Marco Mendes, Cecília Silva, Mário Góis, Helena Viana, Fernando Nolasco,
Kidney disease is frequent in HIV-patients. We present a case of a 44-year-old woman, with known uncontrolled HIV infection and chronic kidney disease due to HIV-associated nephropathy. After starting dolutegravir, the patient developed eosinophilia and worsening kidney function. A kidney biopsy confirmed the diagnosis of acute interstitial nephritis. Given the time relation with dolutegravir introduction, it was deemed the culprit medication. Dolutegravir was stopped, and corticosteroids were initiated, ...
Tópico(s): Renal Diseases and Glomerulopathies
2021 - Elsevier BV | Nefrología
Natalia Egri, Victòria Olivé, José Hernández‐Rodríguez, Pedro Castro, Catherine De Guzman, Libertad Heredia, Ana Castellet Segura, M. Dolores Fernandez, Noemi de Moner, María Torradeflot, Judit Ballús, Robert Martinez, Mario Vazquez, Marta Vidal Costa, Carlota Dobaño, Massimiliano Mazza, L. Mazzotti, Mariona Pascal, Manel Juan, Azucena González-Navarro, Hugo Calderón,
Cellular and humoral immune responses are essential for COVID-19 recovery and protection against SARS-CoV-2 reinfection. To date, the evaluation of SARS-CoV-2 immune protection has mainly focused on antibody detection, generally disregarding the cellular response, or placing it in a secondary position. This phenomenon may be explained by the complex nature of the assays needed to analyze cellular immunity compared with the technically simple and automated detection of antibodies. Nevertheless, a ...
Tópico(s): Long-Term Effects of COVID-19
2022 - Frontiers Media | Frontiers in Immunology
Bernardo Marques da Costa, David Navarro, Mário Góis, Helena Viana, Joaquim Calado, Fernanda Carvalho, Fernarndo Nolasco,
INTRODUCTION AND AIMS: Interstitial nephritis are a protean group of renal diseases with various aetiologies, manifestations, duration and severity, but few therapeutic options.They are typically divided into acute (AIN) and chronic (CIN) interstitial nephritis.The goal of this work was to review our centre's last 10 years' experience on this group of diseases.METHODS: Review of clinical records and pathology reports.RESULTS: We identified 32 patients (33 biopsies) with AIN, with an average age of ...
Tópico(s): Nephrotoxicity and Medicinal Plants
2018 - Oxford University Press | Nephrology Dialysis Transplantation
Produção Nacional
Revisado por pares
Herikson Araújo Costa, Antonio Carlos Silva‐Filho, Carlos José Moraes Dias, Vicenilma Andrade Martins, Thiago Teixeira Mendes, André Scott Rabelo, Francisco Navarro, Emerson Silami‐Garcia, Cristiano Teixeira Mostarda, Mário Sevílio,
We aimed to analyze the acute autonomic response of obese and eutrophic prepubertal boys to an exergame (EXG) session.Nine eutrophic (8.89 ± 2.71 years of age and 16.42% ± 6.30% body fat) and nine obese boys (8.70 ± 1.16 years of age and 40.76% ± 4.2% body fat) participated. Nutritional state was determined using World Health Organization guidelines. Variables were collected at rest, immediately post (IP), and 60 minutes after a 20 minutes EXG session. Autonomic nervous system (ANS) activity was assessed using ...
Tópico(s): Health and Lifestyle Studies
2017 - Mary Ann Liebert, Inc. | Games for Health Journal
Alvaro Manuel Rodriguez-Rodriguez, Marta De la Fuente-Costa, Mario Escalera-de la Riva, Fernando Domínguez‐Navarro, Borja Pérez‐Domínguez, Gustavo Paseiro-Ares, José Casaña, María Blanco‐Díaz,
Background: Prostate and colorectum cancers rank among the most common cancers, and incontinence is a significant postsurgical issue affecting the physical and psychological well-being of cancer survivors. Social media, particularly YouTube, has emerged as a vital source of health information. While YouTube offers valuable content, users must exercise caution due to potential misinformation. Objective: This study aims to assess the quality of publicly available YouTube videos related to incontinence ...
Tópico(s): Patient-Provider Communication in Healthcare
2024 - Multidisciplinary Digital Publishing Institute | Healthcare
Rui Barata, Bernardo Marques da Costa, David Navarro, Marco Mendes, Cecília Silva, Mário Góis, Helena Viana, Fernando Nolasco,
Kidney disease is frequent in HIV-patients. We present a case of a 44-year-old woman, with known uncontrolled HIV infection and chronic kidney disease due to HIV-associated nephropathy. After starting dolutegravir, the patient developed eosinophilia and worsening kidney function. A kidney biopsy confirmed the diagnosis of acute interstitial nephritis. Given the time relation with dolutegravir introduction, it was deemed the culprit medication. Dolutegravir was stopped, and corticosteroids were initiated, ...
Tópico(s): Renal Diseases and Glomerulopathies
2022 - Elsevier BV | Nefrología (English Edition)
Produção Nacional
Revisado por pares
Paula Carolina Mendes Santos, Analia Gabriella Borges Ferraz Facury, Lenita Marangoni Lopes, Mário Alexandre Coelho Sinhoreti, Daniel Navarro da Rocha, Lourenço Correr-Sobrinho, Ana Rosa Costa, José Guilherme Neves,
Tópico(s): Dental Implant Techniques and Outcomes
2025 - Elsevier BV | International Orthodontics
Produção Nacional
Revisado por pares
Reginaldo Luiz do Nascimento, Francisco Navarro, Mário Sevílio, Ricardo Ariel Costa Souza, Sérgio Rodrigues Moreira,
RESUMOO objetivo deste estudo foi verificar a associação entre indicadores antropométricos e aptidão aeróbia com a reatividade vascular de pressão arterial (RV PA ) em homens saudáveis.Quarenta indivíduos do sexo masculino (27.3 ± 6.3 anos; 77.2 ± 11.5 kg; 175.7 ± 6.9 cm) realizaram medidas de índice de massa corporal (IMC), circunferência da cintura (CC), relação cintura/quadril (RCQ), percentual de gordura (%G), consumo máximo de oxigénio (VO 2 max) e um teste de RV PA (Cold Pressor Test -CPT) com imersão da mão ...
Tópico(s): Physical Activity and Health
2014 - Desafio Singular | Motricidade
Produção Nacional
Revisado por pares
Mário Luis Ferreira da Silva, Matheus Carvalho Barbosa Costa, Saulo de Freitas Gonçalves, Rudolf Huebner, Túlio Pinho Navarro,
Tópico(s): Coronary Interventions and Diagnostics
2024 - Springer Science+Business Media | Biomechanics and Modeling in Mechanobiology
R.J. Jiménez-López, José Lorenzo Romero-Trevejo, Lourdes Fernández-Romero, Laura Martín-Chaves, Miguel Romero‐Cuevas, Ana Isabel Molina-Ramos, María J. Sánchez-Quintero, Mora Murri, Francesco Costa, Vicente Bodı́, Mario Gutiérrez‐Bedmar, Jorge Rodríguez‐Capitán, Francisco Javier Pavón, Manuel F. Jiménez‐Navarro,
: Coronary artery disease (CAD) and type-2 diabetes mellitus (T2DM) are characterized by chronic low-grade inflammation. However, measuring cytokines typically involves invasive blood sampling, which can be problematic for CAD patients. This study aimed to assess ophthalmological parameters and tear cytokines in patients with CAD, comparing those with comorbid T2DM to those without to understand their inflammatory profiles.
Tópico(s): Ocular Surface and Contact Lens
2024 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Mario Clemente Zaldívar-Salazar, Julio Sanfort-Navarro,
Se presentan los resultados del calculo de los indices tecnico-explotativos y productividad para una muestra de 55 maquinas cosechadoras de cana KTP-2 y 13 DTP-2M en nueve complejos de las provincias orientales de Cuba cuando a esta muestra de maquinas se les aplica o no el diagnostico tecnico. En el trabajo se aplica el metodo de foto-cronometraje durante las zafras 1993-1994. 1994-1995, 1995-1996. Se analiza el comportamiento de las maquinas con y sin la aplicacion del diagnostico. En los 82 dias ...
Tópico(s): Agricultural and Food Production Studies
2003 - Costa Rica Institute of Technology | Revista Tecnología en Marcha
Rafael San Juan, Begoña de Dios, David Navarro, Ana García‐Reyne, Carlos Lumbreras, D. Bravo, Elisa Costa, Jorge Morales, C. Jiménez, Mario Fernández‐Ruiz, Francisco López‐Medrano, José María Aguado,
Background: EBV DNAemia (EBVd) has been suggested as a surrogate marker of immunosuppression following SOT. Monitoring EBVd might help to identify patients at highest risk for late immunosuppression-related adverse events. Methods: We analyzed a cohort of SOT recipients at our institution (2003-2005) who survived more than 180 days after transplant. Patients were followed until March, 2010. EBVd determined in whole blood by real-time PCR assay Abbott EBV PCR KIT (Abbott Diagnostics, Chicago, Ill, USA) ...
Tópico(s): Polyomavirus and related diseases
2012 - Wolters Kluwer | Transplantation
Rafael San Juan, Begoña de Dios, Diana C. Cicua Navarro, Ana García‐Reyne, Carlos Lumbreras, D. Bravo, Elisa Costa, Jorge Morales, C. Jiménez, Mario Fernández‐Ruiz, Francisco López‐Medrano, J. M. Aguado,
Background: EBV DNAemia (EBVd) has been suggested as a surrogate marker of immunosuppression following SOT. Monitoring EBVd might help to identify patients at highest risk for late immunosuppression-related adverse events. Methods: We analyzed a cohort of SOT recipients at our institution (2003-2005) who survived more than 180 days after transplant. Patients were followed until March, 2010. EBVd determined in whole blood by real-time PCR assay Abbott EBV PCR KIT (Abbott Diagnostics, Chicago, Ill, USA) ...
Tópico(s): Polyomavirus and related diseases
2012 - Wolters Kluwer | Transplantation
Pablo Torres-Salomón, Jorge Rodríguez‐Capitán, Miguel A. Molina‐Cabello, Karl Thurnhofer‐Hemsi, Francesco Costa, Pedro L. Sánchez, Mario Antonio Muñoz-Muñoz, Ada del Mar Carmona-Segovia, Miguel Romero‐Cuevas, Francisco Javier Pavón, Manuel F. Jiménez‐Navarro,
The prognostic impact of non-obstructive coronary artery disease (CAD) remains controversial. Therefore, the objective of this study is to assess the long-term prognostic significance of non-obstructive CAD using machine learning models. We designed a multicenter retrospective, longitudinal, and observational study that included 3265 patients classified into three groups: 1426 patients with lesions < 20%, 643 patients with non-obstructive CAD (lesions 20–50%), and 1196 patients with obstructive CAD ( ...
Tópico(s): Artificial Intelligence in Healthcare
2024 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Herikson Araújo Costa, Ednei Costa Maia, Raphael Furtado Marques, Ayla Flávia Guimarães Frazão, Jurema Gonçalves Lopes de Castro Filha, Francisco Navarro, Mário Norberto Sevílio de Oliveira,
Tópico(s): Sports Performance and Training
2014 - Colégio Brasileiro de Ciências do Esporte | Revista Brasileira de Ciências do Esporte
Produção Nacional
Revisado por pares
Herikson Araújo Costa, Ednei Costa Maia, Raphael Furtado Marques, Ayla Flávia Guimarães Frazão, Jurema Gonçalves Lopes de Castro Filha, Francisco Navarro, Mário Norberto Sevílio de Oliveira,
O objetivo deste estudo foi avaliar o nível de desidratação a partir do balanço hídrico e da Densidade da Urina (Du) em corredores de meia maratona. Participaram do estudo 18 indivíduos do sexo masculino. A ingesta hídrica foi "ad libitum" e realizou-se análise da Du no início e ao final da corrida, bem como medidas de pesagem e estatura. As condições ambientais (33,30 ± 5,30 ºC e 57,50 ± 13,60% de URA) foram registradas por meio de termo-higrômetro digital. Os indivíduos terminaram e começaram a prova ...
Tópico(s): Sports Performance and Training
2014 - Colégio Brasileiro de Ciências do Esporte | Revista Brasileira de Ciências do Esporte
Josu Iraola‐Truchuelo, Gloria Iacoboni, Laura Palomo, Victor Navarro Garcés, Josep Castellví, Alba Mas, Lara Nonell, Luis Antonio Mayor, Victoria Dourdil, Tomas Garcia Cerecedo, Oriana López Godino, Mario Sánchez-Salinas, Cecilia Carpio, Marta Crespo, Ángel Serna, Alba Cabirta Touzón, Marc Bosch, Cristina Seral García, Pere Barba, Francesc Bosch, Pau Abrisqueta Costa,
Introduction: BsAbs and CAR T-cell therapy have revolutionized the treatment landscape of patients with relapsed/refractory (R/R) LBCL. Regrettably, less than 40% of patients will attain durable responses, and determinants of response remain unclear. Our aim was to identify tumoral characteristics that can predict resistance to CAR T-cell therapy and BsAbs in LBCL patients. Methods: We retrospectively collected clinical data and obtained pre-treatment formalin-fixed and paraffin-embedded specimens ...
Tópico(s): Lymphoma Diagnosis and Treatment
2023 - Elsevier BV | Blood