Benoît J. Gentil, Gia-Thanh Lai, Marie Ménade, Roxanne Larivière, Sandra Minotti, Kalle Gehring, J. Paul Chapple, Bernard Brais, Heather D. Durham,
... sacsin deficiency.-Gentil, B. J., Lai, G.-T., Menade, M., Larivière, R., Minotti, S., Gehring, K., Chapple, ...
Tópico(s): DNA Repair Mechanisms
2018 - Wiley | The FASEB Journal
Danielle Naville, Claudie Pinteur, Nathalie Véga, Yoan Menade, M. Vigier, Alexandre Le Bourdais, Emmanuel Labaronne, Cyrille Debard, Céline Luquain‐Costaz, Martine Bégeot, Hubert Vidal, Brigitte Le Magueresse‐Battistoni,
... metabolic diseases.—Naville, D., Pinteur, C., Vega, N., Menade, Y., Vigier, M., Le Bourdais, A., Labaronne, E., ...
Tópico(s): Toxic Organic Pollutants Impact
2013 - Wiley | The FASEB Journal
Marie Ménade, Guennadi Kozlov, Jean‐François Trempe, Harshit Pande, Solomon Shenker, Sihara Wickremasinghe, Xinlu Li, Hamed Hojjat, Marie‐Josée Dicaire, Bernard Brais, Peter S. McPherson, Michael Wong, Jason C. Young, Kalle Gehring,
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disease that is caused by mutations in the SACS gene. The product of this gene is a very large 520-kDa cytoplasmic protein, sacsin, with a ubiquitin-like (Ubl) domain at the N terminus followed by three large sacsin internal repeat (SIRPT) supradomains and C-terminal J and HEPN domains. The SIRPTs are predicted to contain Hsp90-like domains, suggesting a potential chaperone activity. In this work, we report the ...
Tópico(s): Mitochondrial Function and Pathology
2018 - Elsevier BV | Journal of Biological Chemistry
... Las antefijas reproducen los bustos de sátiros y ménades. Se trata de un material importado que tiene ...
Tópico(s): Historical and Architectural Studies
2018 - Spanish National Research Council | Archivo Español de Arqueología
Daniel Calles-Garcia, Meng Yang, Naoto Soya, Roberto Melero, Marie Ménade, Yukishige Ito, Javier Vargas, Gergely L. Lukács, Justin M. Kollman, Guennadi Kozlov, Kalle Gehring,
The enzyme UDP-glucose:glycoprotein glucosyltransferase (UGGT) mediates quality control of glycoproteins in the endoplasmic reticulum by attaching glucose to N-linked glycan of misfolded proteins. As a sensor, UGGT ensures that misfolded proteins are recognized by the lectin chaperones and do not leave the secretory pathway. The structure of UGGT and the mechanism of its selectivity for misfolded proteins have been unknown for 25 years. Here, we used negative-stain electron microscopy and small-angle ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2017 - Elsevier BV | Journal of Biological Chemistry
Jean‐François Trempe, Klára Grantz Šašková, Monika Sivá, Colin D.H. Ratcliffe, Václav Veverka, Annabelle Hoegl, Marie Ménade, Xin Feng, Solomon Shenker, Michal Svoboda, Milan Kožíšek, Jan Konvalinka, Kalle Gehring,
Abstract The eukaryotic Ddi1 family is defined by a conserved retroviral aspartyl protease-like (RVP) domain found in association with a ubiquitin-like (UBL) domain. Ddi1 from Saccharomyces cerevisiae additionally contains a ubiquitin-associated (UBA) domain. The substrate specificity and role of the protease domain in the biological functions of the Ddi family remain unclear. Yeast Ddi1 has been implicated in the regulation of cell cycle progression, DNA-damage repair, and exocytosis. Here, we investigated ...
Tópico(s): Enzyme Structure and Function
2016 - Nature Portfolio | Scientific Reports
... Sauvé V, Grenier K, Seirafi M, Tang MY, Ménade M, Al-Abdul-Wahid S, Krett J, Wong ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2014 - Springer Nature | The EMBO Journal
Felix Randow, Richard J. Youle,
... V. Grenier K. Seirafi M. Tang M.Y. Ménade M. Al-Abdul-Wahid S. Krett J. Wong ...
Tópico(s): Calcium signaling and nucleotide metabolism
2014 - Cell Press | Cell Host & Microbe
Jean-François Trempe, Véronique Sauvé, Karl Grenier, Marjan Seirafi, Matthew Y. H. Tang, Marie Ménade, M. Sameer Al‐Abdul‐Wahid, Jonathan D. Krett, Kathy Wong, Guennadi Kozlov, Bhushan Nagar, Edward A. Fon, Kalle Gehring,
Parkin Enhanced? Inactivation of parkin, an E3 ubiquitin ligase, is responsible for a familial form of Parkinson's disease and may be involved in sporadic forms as well. Trempe et al. (p. 1451 , published online 9 May) present the crystal structure of full-length parkin in an autoinhibited configuration. Guided by the structure, mutations were designed that activated parkin both in vitro and in cells. Because parkin is neuroprotective, the structure provides a framework for enhancing parkin function ...
Tópico(s): Click Chemistry and Applications
2013 - American Association for the Advancement of Science | Science
... en mesure de s’approcher du territoire des Ménades sans être remarqué. En particulier, le dieu le ...
Tópico(s): Historical, Religious, and Philosophical Studies
2013 - | L antiquité classique
R. Andrew Byrd, Allan M. Weissman,
... Sauve V, Grenier K, Seirafi M, Tang MY, Menade M, Al-Abdul-Wahid S, Krett J, Wong ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2013 - Springer Nature | The EMBO Journal
Edna Matta‐Camacho, Guennadi Kozlov, Marie Ménade, Kalle Gehring,
UBR5 ubiquitin ligase (also known as EDD, Rat100 or hHYD) is a member of the E3 protein family of HECT (homologous to E6-AP C-terminus) ligases as it contains a C-terminal HECT domain. In ubiquitination cascades involving E3s of the HECT class, ubiquitin is transferred from an associated E2 ubiquitin-conjugating enzyme to the acceptor cysteine of the HECT domain, which consists of structurally distinct N- and C-lobes connected by a flexible linker. Here, the high-resolution crystal structure of the ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2012 - Wiley | Acta Crystallographica Section F Structural Biology and Crystallization Communications
Janine Koepke, Florian Kaffarnik, Carl Haag, Kathi Zarnack, Nicholas M. Luscombe, Julian König, Jernej Ule, Ronny Kellner, Dominik Begerow, Michael Feldbrügge,
... 281Crossref PubMed Scopus (90) Google Scholar, 21Kozlov G. Ménade M. Rosenauer A. Nguyen L. Gehring K. Molecular ...
Tópico(s): Protein Tyrosine Phosphatases
2011 - Elsevier BV | Molecular & Cellular Proteomics
Guennadi Kozlov, Marie Ménade, Angelika Rosenauer, Long V. Nguyen, Kalle Gehring,
Tópico(s): RNA modifications and cancer
2010 - Elsevier BV | Journal of Molecular Biology
Jaclyn M. Jansen, Antony G. Wanless, Christopher Seidel, Eric L. Weiss,
... translation, is critical for cellular differentiation [1Paquin N. Ménade M. Poirier G. Donato D. Drouet E. Chartrand ...
Tópico(s): Fungal and yeast genetics research
2009 - Elsevier BV | Current Biology
Nicolas Paquin, Marie Ménade, Guillaume Poirier, Damiane Donato, Emmanuel Drouet, Pascal Chartrand,
In S. cerevisiae, the ASH1 mRNA is localized at the bud tip of late-anaphase cells, resulting in the exclusive sorting of Ash1p to the daughter cell nucleus. While the mechanism behind the localization of this transcript has been well studied, the regulation of its translation is still poorly understood. We now report that the RNA binding protein Khd1 interacts with the ASH1 mRNA localization element E1 and with the C-terminal domain of eIF4G1 to regulate the translation of this transcript. Khd1p ...
Tópico(s): Fungal and yeast genetics research
2007 - Elsevier BV | Molecular Cell
Victoria Best, Alex Hughes, Kate Ince,
... Batarde/the failure of love, Alex Hughes Sophie Menade - the wrting of Monique Wittig, Jennifer Birkett Helene ...
Tópico(s): French Literature and Critical Theory
1997 - Modern Humanities Research Association | The Modern Language Review
Marie-Christine Villanueva-Puig,
Sont ici réunies les représentations de figures féminines dans l'entourage de Dionysos sur les vases attiques à figures rouges de la fin de l'archaïsme. Huit éléments se dégagent de cet ensemble d'images au nombre d'environ 370 : le cadre minéral, les éléments végétaux, les éléments animaux, la musique , la danse , le vin, la composante érotique et la composante cultuelle. Souvent ces images préfigurent le personnage littéraire et plus tardif des Bacchantes de la tragédie d'Euripide.
Tópico(s): Archaeology and Historical Studies
1992 - Bordeaux Montaigne University | Revue des Études Anciennes
Marie-Christine Villanueva-Puig,
From the representations of Attic vase painting of the sixth and fifth centuries and the comparison of this imagery with literary sources, I study the relations between the maenad and wine. Usually the Greek woman has no contact with wine. But in the cult of Dionysos is she allowed to participate in the ritual wine-drinking ?
1988 - Bordeaux Montaigne University | Revue des Études Anciennes
... folie et la communiquent. Quand il pousse les Ménades au combat ou frappe de panique une armée, ...
Tópico(s): Historical and Literary Analyses
1985 - Association of Greek Studies | Revue des Études Grecques
Marie-Christine Villanueva Puig,
A propos de quelques noms de ménades attiques inscrits (pp. 159-171) Ont été sélectionnés parmi les nombreux noms de ménades inscrits sur les vases attiques, quelques exemples susceptibles ...
Tópico(s): Linguistics and Discourse Analysis
1998 - | Mètis Anthropologie des mondes grecs anciens
Xinlu Li, Marie Ménade, Guennadi Kozlov, Zheping Hu, Zheng Dai, Peter S. McPherson, Bernard Brais, Kalle Gehring,
Sacsin is a large protein implicated in the neurodevelopmental and neurodegenerative disease autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), which features the loss of Purkinje neurons in the cerebellum. Although the domain architecture of sacsin suggests that it is a neuronal chaperone assisting in protein quality control, the precise function of sacsin remains elusive. Using fluorescence polarization (FP) assays, we confirmed that the HEPN domain of sacsin binds to nucleotides ...
Tópico(s): RNA Research and Splicing
2015 - Public Library of Science | PLoS ONE
... alegórica de las cuatro Estaciones y con dos Ménades. El pavimento y las pinturas parietales se datan ...
Tópico(s): Ancient Mediterranean Archaeology and History
2010 - National University of Distance Education | Espacio Tiempo y Forma Serie I Prehistoria y Arqueología
... el caso de Italica aparecen personajes femeninos, quiza menades. Estas esculturas eran estatuas-fuentes y formaban parte ...
Tópico(s): Classical Antiquity Studies
1994 - University of Seville | HABIS
The Greek imaginary uses the name of Menades to refer to one of the mythical paradigms of femininity and is deep-rooted affinity with nature. As can be seen in Euripides’ ... in so far as the savageness of the menades can lead to a murderous violence.
Tópico(s): Archaeology and Historical Studies
1999 - University of Lisbon | Euphrosyne
Marie-Christine Villanueva Puig: Ménades. Recherches sur la genèse iconographique du thiase féminin de Dionysos des origines à la fin de la période archaïque. Paris: ...
Tópico(s): Historical, Religious, and Philosophical Studies
2013 - C.H. Beck | Gnomon
... imaginaire dionysiaque et la figure traditionnelle de la ménade en délire ; les historiens en fustigent, non sans ...
Tópico(s): Historical, Religious, and Philosophical Studies
2007 - | ASDIWAL Revue genevoise d anthropologie et d histoire des religions
Juan Carlos Guerrero-Hernández,
Como contribución al estudio de la producción de videopoesÃa hecha por mujeres, se analiza y discute una de las primeras obras de videopoesÃa producida en el continente americano. En esta obra la artista, Margarita Becerra Cano, apuesta por una decidida y rizomática desterritorialización del poema escrito y propone una creación audiovisual que con irreverencia desgarra la figura de la autoridad del poeta hombre. La autora recurre a diversos tipos de traducciones a fin de trazar videográficamente ...
Tópico(s): Comparative Literary Analysis and Criticism
2022 - University of Chile | Revista chilena de literatura
Le ménadisme est sans doute le phénomène rituel grec qui suscite encore aujourd’hui le plus de fascination et d’interrogations. Bien qu’un grand nombre de sources littéraires et iconographiques se rapportent à ce sujet, la réalité historique du ménadisme reste néanmoins difficile à appréhender. Ce que nous en savons et ce qui nous a été transmis relève avant tout de l’image mythico-poétique, une idée préformée d’un comportement et d’un état d’esprit propres à l’enthousiasme dionysiaque. Réalité ...
Tópico(s): French Historical and Cultural Studies
2019 - | Théologiques
... del ar ekonomisk beroende av sina man. Kvinnorna menade att islam gav dem frid, samt gav mojlighet ...
Tópico(s): Migration, Refugees, and Integration
2016 - University of Nebraska Press | Frontiers A Journal of Women Studies