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Jornais Acesso aberto

Ernest Rivers, R. G. Rolfe, Clifford E. F. Narl,

... Echoes from the Societies, Notices of Apparatus The "Meda" Camera, Title and Notice Slides, Number Your Hands, ...

1901 - Gale Group | NCCO Photography

Artigo Revisado por pares

Sabine Le Gurun, David Martín, Andrea Formenton, Pierre Maechler, Dorothée Caille, Gérard Waeber, Paolo Meda, Jacques‐Antoine Haefliger,

... barely increase these functions after stimulation (6Bosco D. Meda P. Endocrinology. 1991; 129: 3157-3166Crossref PubMed Scopus ( ... Ullrich S. Charollais A. Philippe J. Orci L. Meda P. J. Cell Biol. 1995; 131: 1561-1572Crossref ... Soria B. Wollheim C.B. Herrera P.L. Meda P. J. Clin. Invest. 2000; 106: 235-243Crossref ... Serre-Beinier V. Amato G. Haefliger J.A. Meda P. Condorelli D.F. Brain Res. 2000; 865: ... Charollais A. Haefliger J.A. Condorelli D.F. Meda P. Diabetes. 2000; 49: 727-734Crossref PubMed Scopus ( ...

Tópico(s): Heat shock proteins research

2003 - Elsevier BV | Journal of Biological Chemistry

Jornais Acesso aberto

Percy Lund, W. M. Dodson, Ernest Marriage, H. E. Sercombe, E. T. Wright,

... The Enquiry Bureau, On the Market The "Tribees Meda" Hand Camera, Busch's "Vademecum" Spectacle Lens Set, ...

1900 - Gale Group | NCCO Photography

Artigo Revisado por pares

Elena Escubedo, Sònia Abad, Imma Torres, Jorge Camarasa, David Pubill,

... effects of MDMA and its metabolite alpha-methyldopamine (MeDA) on several molecular targets, mainly the dopamine and ... metabolite in the neurotoxicity of MDMA in rodents. MeDA had no affinity for the serotonin transporter but ... in contrast to the effect of MDMA. Moreover, MeDA inhibited the uptake of dopamine into the serotonergic terminal and also MAOB activity. MeDA inhibited dopamine uptake with a lower IC50 value than MDMA. After drug washout, the inhibition by MeDA persisted while that of MDMA was significantly reduced. ...

Tópico(s): Psychedelics and Drug Studies

2010 - Elsevier BV | Neurochemistry International

Court testimony Acesso aberto

H. L. Norton Traill,

... Court Reports Letter. From H. L. Norton Traill. Meda District.

0000 - Gale Group | NCCO EuropeAfrica

Artigo Acesso aberto Revisado por pares

Florent Allagnat, Florian Alonso, David Martín, Amar Abderrahmani, Gérard Waeber, Jacques‐Antoine Haefliger,

... Klee P. Peyrou M. Populaire C. Zulianello L. Meda P. Biochim. Biophys. Acta. 2005; 1719: 82-101Crossref ... Formenton A. Maechler P. Caille D. Waeber G. Meda P. Haefliger J.A. J. Biol. Chem. 2003; ... Charollais A. Haefliger J.A. Condorelli D.F. Meda P. Diabetes. 2000; 49: 727-734Crossref PubMed Scopus ( ... Kruger O. Plum A. Nepote V. Herrera P. Meda P. Willecke K. Exp. Cell Res. 2004; 294: ... Formenton A. Maechler P. Caille D. Waeber G. Meda P. Haefliger J.A. J. Biol. Chem. 2003; ... Charollais A. Caille D. Zufferey R. Trono D. Meda P. J. Cell Sci. 2003; 116: 2285-2294Crossref ...

Tópico(s): Heme Oxygenase-1 and Carbon Monoxide

2007 - Elsevier BV | Journal of Biological Chemistry

Jornais Acesso aberto

James Landale, David T. Staples, Alyn Shipton, Anthony Harris, Jon Ashworth, Nick Nuttall, Andrew Pierce, Chris Ward, Grace Bradberry, Simon Barnes, Diana Wildman, Magnus Linklater, Richard Thomson, Robert Miller, Banking Correspondent, Ivo Tennant, Gavin Lumsden, Philip Howard, Hilary Finch, John Simpson, Andrew Lloyd Webber, Jeremy Laurance Health Correspondent, Oliver Lever, George Sivell, Robert Fox, Oliver Holt Football Correspondent, Shirley English and Michael Hornsby, Carl Mortished, I. A. Olson, Morag Preston, T. R. Marshall, John Major, Clare Stewart, Robert Sheehan, Bridge Correspondent, Joe Joseph, Maeve Creber, Rachel Clements, Ruth Gledhill, Religion Correspondent, H. J. Balderson, Russell Jenkins and Arthur Leathley, Patricia Holland, Peter Ball, Debra Craine, Shirley English, Raymond Keene Chess Correspondent, Nicholas Booth, Dareh Gregorian, Michael Evans, Defence Correspondent, Richard Ford Home Correspondent, Alan Hamilton, S. W. Martin Chairman, Rodney Milnes, R. D. Vernon, Marianne Curphey, Insurance Correspondent, Quentin Letts, Audrey Magee, Katherine Bergen, John Kavanagh, Deborah Collcutt, Russell Kempson, Nigel Williamson, Daniel McGrory, Paul Durman, Philip Bassett, Brenda Maddox, Andy Lavender, Belinda Archer, John Hopkins, Jean Mcleod Forbes, John Mendes, Barry Millington, John Hopkins Golf Correspondent, Michael Codron, Adam Jones, Raymond Keene, Polly Newton, Leyla Linton, P. H. S, Chris Partridge, Nigel Hawkes, Bronwen Maddox, Eric Reguly, Sara Mcconnell, Richard Owen, David Powell, Athletics Correspondent, Susan Gray, Sarah Cunningham, Oliver August, Tunku Varadarajan and Dominique Searle, Anne Hudson, Philip Webster, Political Editor, Duncan Weldon, Michael Hornsby, Agriculture Correspondent, Dalya Alberge, David Hands Rugby Correspondent, John Allison, Richard Duce, Geof Wheelwright, Eileen McCabe, Alan Copps, Christopher Walker, Brian MacArthur, Kathryn Knight, Graham Searjeant, Financial Editor, Matthew Parris, Mark Hodkinson, Jane Owen, Peter Riddell, Ben MacIntyre, Ray Hatley, Philip Webster, Simon Jenkins, Fraser Nelson, Tim Jones, Nigel Hawkes Science Editor, Daniel Rosenthal, Nigel Powell, Russell Jenkins and Carol Midgley, Neil Cooper, Adrian Noble, Margaret Jowitt, Editor, Michael Evans, Julia McKenzie, Alasdair Murray, Robert Whymant, Harvey Elliott Air Correspondent, Matthew Bond, Nick Lynam, Anthony Howard, Dr Keyboard, Richard Eyre, Christine Buckley, Industrial Correspondent, Nick Nuttall and Michael Hornsby,

... Picture Gallery Barings offer to be made soon Meda Freeman to rejoin Salomon from EBRD Debonair Sport ...

1997 - Gale Group | TDA

Artigo Revisado por pares

Gladys V. Erives, Serrine S. Lau, Terrence J. Monks,

... metabolite N -methyl-α-methyldopamine ( N -Me-α-MeDA). Thioether (glutathione and N -acetylcysteine) metabolites of N -Me-α-MeDA are neurotoxic and are present in rat brain ... a significant accumulation of the N -Me-α-MeDA thioether metabolites in striatal dialysate. The area under ... for 5-(glutathion- S -yl)- N -Me-α-MeDA increased 33% between the first and fourth injections ... 5-bis-(glutathion- S -yl)- N -Me-α-MeDA. Likewise, accumulation of the mercapturic acid metabolites was ... 5-( N -acetylcystein- S -yl)- N -Me-α-MeDA (35%) and 2,5-bis-( N -acetylcystein- S - ...

Tópico(s): Psychedelics and Drug Studies

2007 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics

Artigo Acesso aberto Revisado por pares

H. Zhang, X. Chen, M.R. Sairam,

... identified a novel mesenteric estrogen-dependent adipose gene (MEDA-4) selectively up-regulated in a depot-specific manner in mesenteric adipose tissue. Meda-4 cloned from both mouse and human adipose ... 34-kDa cytosolic protein with 91% homology. Mouse Meda-4 mRNA is expressed highest in visceral adipose ... and localizes predominantly in the adipocyte fraction. Human MEDA-4 is also more abundant in omental fat ... in obese patients. In 3T3-L1 cells endogenous Meda-4 expression increases early during differentiation, and its ...

Tópico(s): Adipose Tissue and Metabolism

2012 - Oxford University Press | Endocrinology

Jornais Acesso aberto

R. P. Kinsella, Edward Owen, David Southern, David Tytler, DJM, Sheila Gunn, Tim Judah and Dessa Trevisan, Barry Trowbridge, Simon Barnes, David Rhys Jones, Ross Tieman, Industrial Correspondent, Michael Stevenson, Karl Knight, Duncan Graham, F. N. Cogswell, Carol Leonard, Richard Streeton, Stuart Jones Football Correspondent, Jay Andrews, David Watts, Diplomatic Correspondent, Gerald Davies, Ray Clancy, Bernard Levin, Martin Fletcher, Noel Falconer, Bryan Stiles, Julian Desborough, Ruth Gledhill, Religion Correspondent, Peter Davenport, Peter Stothard, US Editor, Peter Ball, John Forrest, Callum Beaton, Caroline Sullivan, Louise Taylor, Rachel Kelly, Robert Seely, Martin Barrow, Libby Purves, Peter Bills, Ray Kennedy, Philip Webster and Kerry Gill, Harvey Elliott and Matthew Bond, Michael McCarthy, Environment Correspondent, John O'Leary, Philip Robinson, John Young, Anatole Kaletsky, Charles Bremner, Joseph Connolly, Roy Denman, Jeremy Laurance Social Services Correspondent, Neil Bennett Banking Correspondent, Mary MacLure, Robert Balchin, Chairman, Andrew Irvin, John Hennessy, Paul Taylor, Oscar Moore, Michael McCarthy Environment Correspondent, John Woodcock, Douglas Broom Local Government Correspondent, George Brock, Brenda Polan, Sydney Friskin, Nicholas Harling, David Miller, Philip Webster, Chief Political Correspondent, Judi Bevan, Matthew D'ancona, Education Reporter, Alison Roberts, Norman Hammond, David Watts, Joseph de Courcy (Editor), Raymond Keene, David Robinson, Alan Lee, Cricket Correspondent, Geoff King, Alix Ramsay, Paul Griffiths, Matthew d'Ancona, Bernard Carnell, Richard Evans, Peter Spencer, David Powell, Athletics Correspondent, Ian Ross, Peter Keeling, Norman Willis, General Secretary, Brian Beel, Keith MacKlin, P. E. Whitlock, David Hands Rugby Correspondent, Irene Kunii, David Young, Edward Gorman, Ireland Correspondent, Philip Webster Chief Political Correspondent, Sara McConnell, Christopher Walker, Iola Smith, P. Allington, Colin Narbrough, Economics Correspondent, Clive White, Matthew Parris, Charlotte Fisher, Catherine Milford (Moderator), Michael Seely, Thomson Prentice, Medical Correspondent, Peter Riddell, Alan Lee Cricket Correspondent, Richard Beeston, Michael Phillips, Philip Pangalos, William Cash, Tim Gardam (Editor), Benedict Nightingale, Derek Harris, John Phillips, Matthew Bond, Peter Robinson, Peter Roebuck, Philip Jacobson, Colin McQuillan, Andrew Longmore, Tennis Correspondent, Mary Dejevsky,

... team concludes the winter Olympic Games without a meda For the Record Today's Fixtures Timing costs ...

1992 - Gale Group | TDA

Artigo Revisado por pares

Yong Wang, Xiang Jian, Zixing Cai,

... model-based multiobjective estimation of distribution algorithm (RM-MEDA) has been proposed for solving continuous multiobjective optimization problems with variable linkages. RM-MEDA is a kind of estimation of distribution algorithms ... therefore, modeling plays a critical role. In RM-MEDA, the population is split into several clusters to ... fixed number of clusters is recommended in RM-MEDA when solving different kinds of problems. However, based ... a significant effect on the performance of RM-MEDA. Motivated by the above observation, in this paper ...

Tópico(s): Evolutionary Algorithms and Applications

2012 - Elsevier BV | Applied Soft Computing

Jornais Acesso aberto

J Cason, Kelth Westhead, John Dugdale, Joe Elder, Nigel Sherwin, Mark Strong, Barbara Hall, Robert Craik, Simon Armitage, Chris Curtis, David Mills, Peter Whittle, Sally Brock, Martyn Powls, Nicholas Rufford, Jason Dawe, Laura Bailey, Pam Barrett, Professor Gideon Garter, Kay Carter, Jonathan Miller, Bruce Millar, Andrew Longmore, Jane Mulkerrins, Susan d'Arcy, Ian Critchiey, Gareth Walsh, Phil Green, Frank Whitford, Timothy Garton Ash, Ivo Tennant, David Landers, Matthew Davis, Barry J Holmes, Caroline Brannigan, Ferdinand Mount, David Gower, Keith Wood, Kate reardon, Vivek Singh, Chris Mackey, Allan Brown, P D, David Smith, Tim Richards, Richard Bond, Steven Poole, David Cracknell Political Editor, Nick Pitt, Neil Wormald, E P, Andrew Sullivan, Robert Fox, Clive Davis, Ian Poulter, Ed Balls, Jemima French, Joseph Dunn, Martin James, Simon Wilde, B M, Robert Winnett, Jeremy Seal, Dipesh Gadher Transport Correspondent, Irwin Stelzer, Adrian Furnham, Robert Hewison, Peter Wilson, Rosie Millard, David Dougill, Daisy de Villeneuve, Paul Durkin, Eva Celer, Alan Rhodes, Isabella Tree, Steve Boyd, David Hewson, David Elstein, D Milburn, David Bond, Frank Dobson, Angus Palmer, Margarette Driscoll, Hugh Canning, Lucy Rouse, Jeremy Clarkson, Ryan Gilbey, Philip Smith, Peter Conradi, Edward Porter, Stewart Lee, Victoria Segal, Michael Portillo, Patricia Nicol, Anthony Peregrine, Henry Schukman, Sarah Dempster, Theresa Villiers, Dave Pollard, Shirely Williams, Richard Need, Richard Fletcher, Chitralekha Mehta, Ziad Al-Najim, Greg Struthers, George Perry, Lydia Slater, Domnici Bates, Adam Nathan, J Atherton, Andrew Porter Deputy Political Editor, Grand Sums, Talib Choudhry, Ian Wright, Johnathan Northcroft, Susan D'Arcy, J A Charial, Stuart Morris, Susan Exshaw, Paul Donovan, Adam Nathan Defence Correspondent, Richard Titchener, Penelope Hobhouse, Vincent Crump, Paul Kimmage, Hugh McIlvanney, Lee Taylor, Frank Walsh, Chris Woodhead, Richard Vernon, Lucinda Kemeny, Jasper Gerard, Alan Broad, Iain Gately, David Turner, Philippa Forrester, Garth Pearce, Nicholas Hellen, John Follain, Vanora Bennett, Paul Driver, Ian Hawkey, Shelley Von Strunckel, Alex Clark, Christopher Morgan, David Leppard, Phill Baker, Ed Gorman, Alicia Wyllie, Dave Hannigan, Richard Girling, Mark Edwards, Rachel Bridge, Trevor Hamley, Stephen Amidon, Bonnie Rakhit, Peter Koening, Susan Clark, Tim Clifford, Natalie Garham, Blower, Nell Wormald, Christina Lamb, Hugh Pearmen, Lois Rogers, Bob Graham, Raymond Keene, Chris Rawlinson, Gareth Huw Davies, Cosmo Landesman, Zoe Brennan, Denis Pallis, Robbie Hudson, Les Baux de Provence, Diana Wright, Catherine Turner, Dr Mark Tilden, Barry Flatman tennis correspondent, Stephen Jones, Dominic O'Connell, Peter Koenig, Barry Flatman, Louise Armitstead, Michael Wright, Robbie Burns, Imogen Edwards-Jones, Adrienne Connors, Lynda Mourad, Caroline Donald, Jeremy Lewis, Rob Ryan, Jessica Brinton, David Walsh, Barry Flatman Tennis Correspondent, John Stern, Trevor Lewis, Sally Klnnes, Gareth Southgate, Bryan Appleyard, Helen Stewart, Sarah Keenlyside, Colin McDowell, Stephen Armstrong, John Elliott, Burlington Bertie, Bethan Cole, Victoria O'brien, Roland White, Dr Leyla Sanai, Shane Watson, Sarah Kate Templeton, Maurice Chittenden, Philip Johnstone, Richard Rae, Mark Franchetti, Ray Hutton, George Lucas, Jon Ungoed-Thomas, Dharmasiri Agalawatta, Jonathan Leake, Brendan Simms, Sophie Kirkham, Dan Box, Mike Smith, Clare Francis, T C, John Harlow, Niall Ferguson, Barry Collins, Hunter Davies, Tony Jacklin, John Waples, A A Gill, Lanie Goodman, Melanie McDonagh, Matthew Campbell, Denis Walsh, John Carey, Mary Braid, Simon Jenkins, Stephen Pettitt, Jonathan Leake Science Editor, Imre Karacs, Justin Sparks, Sally Kinnes, Naomi Caine, Daniel Emery, William Simons, Brian Doogan, Ben Dowell, John Aizlewood, Peter Schmeichel, James Knight, Mark Hodson, Andrew Frankel, D Robinson, Joe Lovejoy, Jonathan Futrell, Graham Norwood, Victor Bryant, David Budworth, William Lewis Business editor, Hugh Pearman, Andrew Davidson, Dan Cairns, Simon Sebag Montefiore, John Green, Stewart Mitchell, John Wapies, David Smith Economics Editor, Matt Roberts, Susannah Price, Paul Cairns, Sarah Baxter, Chris Feetenby, Mat Loup, Matthew Goodman, Nick Austin, India Knight, Kate Spicer, Simon Howard, Peter Clowes, Nina Goswami, Tom Holland, Barry Newcombe, Richard Lewis, Sian Griffiths, Karen Robinson, Trevor Phillips,

... s balancing act Beth Tweddele chases an Olympic meda! next month after defending her national all-round ...

2004 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Qusai Al Abdallah, Se-In Choe, Paolo Campoli, Stefanie D. Baptista, Fabrice N. Gravelat, Mark J. Lee, Donald C. Sheppard,

MedA is a developmental regulator that is conserved in the genome of most filamentous fungi. In the pathogenic fungus Aspergillus fumigatus MedA regulates conidiogenesis, adherence to host cells, and pathogenicity. The mechanism by which MedA governs these phenotypes remains unknown. Although the nuclear import of MedA orthologues has been reported in other fungi, no ... or other conserved motifs have been identified within MedA. In this work, we performed a deletion analysis of MedA and identified a novel domain within the C- ...

Tópico(s): Viral Infectious Diseases and Gene Expression in Insects

2012 - Public Library of Science | PLoS ONE

Jornais Acesso aberto

Andrew Robson, James Landale, Phil Yates, Jon Ashworth, Sally Staples, Cath Urquhart, Raymond Snoddy Media Editor, Andrew Eames, Fred Mawer, Stella Shamoon, David Charter Health Correspondent, Hedwig Wahle, Richard Whitehead, Bud Baldaro, Robert Cole, Andrew Pierce, John Fingleton, Portia Colwell, James Moore, Maggie Alderson, Eleanor Fretten, Gary Duncan, Jane MacQuitty, Stephan Bird, Avril Fox, Jill Hartley, Brian Parker, Clive King, Robert Knibbs, David Gray, Paul Hoggart, Francis McCarthy, Mark Souster, Jane Gardam, David Rhys Jones, Michael Evans Defence Editor, Philip Howard, Isabella McRae, Ian Cobain, Adam Mars-Jones, Hilary Finch, Joyce Armstrong Dunn, Roland Watson and Fraser Nelson, David Chater, Angela Court, James Bone, Andrew Pierce and Michael Evans, Richard Irving, E. Jane Dickson, Anne Robinson, Sharon Linnard, GS, SM, Michael Douglas, Kevin Eason, Gerald Davies, Clare Stewart, James Connell, Giles Coren, Antonia Senior, Martin Fletcher, Carl Evans, Pat Gibson, Valerie Elliott Countryside Editor, Shiraz Randeria, Henry Harris, Melanie Tringham, Stewart Tendler Crime Correspondent, Ruth Gledhill, sally Patten Retail Correspondent, Alix Ramsay Tennis Correspondent, Jill Dupleix, Tim Reid, Peter Mandelson, Grainne Gilmore, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Martin Barrow, Jackie Clune, Candida Crewe, Jo Morris, Robin Young, Stephen Farrell, Rodney Milnes, Andy Stephens, Ronald Moss, Giles Whittell and Ben MacIntyre, Norman Griffiths, Olivia Williams, Valerie Elliott Consumer Editor, Christopher Sharp, David Hands, John Lake, Helen Rumbelow, Jonathan Sacks, Mark Thompson, Director, Peter Barnard, Tim Teeman, Mark Court, Edward Gorman, Derwent May, Nicholas Wapshott, Lewis Wolpert, Angela Jameson, Stephen Hargrave, Malcolm Smith, Alison Johnson, JJ, Russell Kempson, Paula Hawkins, Vanora Bennett, Peter Demetriadi, Mary Gold, Jeremy Bremridge, Oliver Kay, Stephen Anderton, Amber Cowan, Brian Jackman, Anne Wareham, David Lister, Mark Atherton, John Stott, Anthony H. Chapman, Jill Sherman Whitehall Editor, Sam Coates, Mark Henderson Science Correspondent, John Hopkins Golf Correspondent, Geoffrey Dean, Rob Wright, Mark Chadbourn, R. V. Kentsley, Charles Jennings, Helen Vaughan-Jones, David Powell Athletics Correspondent, Yvonne Hunter, Raymond Keene, Lewis Smith, Matthew Pryor, Clive Mathieson, Marina Cantacuzino, Lucy Pinney, Paul Wilkinson, James Allcock, Derek Martin, Steve Ager, Margaret Birkinshaw, Michael Oliver, President, Jeannette Hyde, Peter Viggers, Michael Arditti, Jane Hughes, Oliver Holt, Caroline Donald, Helen Nugent, Damian Whitworth, Fiona Terry, Marcel Berlins, Roger Boyes, John Stern, Nick Hasell, Chloë Bryan-Brown, Caroline Morrow Brown, Russell Jenkins and Adam Sage, David Hands Rugby Correspondent, Adam Fresco, Martin Fletcher European Correspondent, Martin Hislop, Steve Jelbert, Anne Ashworth, Primo Levi, Dominic Kennedy, Giles Whittell, Philip Webster Political Editor, Jane Shilling, Mel Webb, Mike Brewer, Harold Ingham, PB, Matthew Parris, Deborah Warner, Jennai Cox, Mark Hodkinson, Chris McGrath, Robert Carnwath, Tim Wapshott, Glen Owen Education Correspondent, Russell Jenkins, Hugh Fearnley-Whittingstall, Walter Gammie, Mark Court Health Industries Correspondent, Peter Edmond, Chairman, Lea Paterson Economics Editor, Harry Jakeman, DC, Derek Dainton, David James, Richard Beeston Diplomatic Editor, Michael Dynes, Ben Macintyre, Alison Gibson, Judith Sutherland, Richard Miles, Graham Searjeant, Susan Long, Gary Duncan Economics Correspondent, Martin Waller, Danny Baker, Fran Littlewood, Carl Mortished International Business Editor, Dr Stephen Castell, Benedict Nightingale, Stuart Birch, Dr Thomas Stuttaford, Jill Crawshaw, Carl Wilkinson, Richard Morrison, Peter Freeman, David Powell, Maurice L. Slevin, Chairman, Tom Chesshyre, Paul Connolly, Neil Cooper, Jennifer Allerton, Technology Director, Fiona Beckett, John Phillips, Allan Hall, K. J. Johnson, Alan Lee Racing Correspondent, Veronica Lee, Penny Perrick, Roland Watson Chief Political Correspondent, Edward Gorman Sailing Correspondent, H. A. Simpson, Catherine Riley Motoring Editor, Patience Wheatcroft, Andrew Palmer, Christopher Irvine, Anne Whiting,

... work, Now, the director turns her attention to Meda Now booking Japes Nationwide choice: Faithfull The five ...

2001 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Chang‐Yi Cui, Janine A. Smith, David Schlessinger, Chi‐Chao Chan,

... T Griggs B Srivastava AK Schlessinger D Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential ... mice (C57BL/6J-Aw-J-Ta6J) (27 males), mEDA-A1 transgenic Tabby (4 males), transgenic mice in ... indicate age of mice. w, weeks Generation of mEDA-A1 transgenic mice was reported previously.17Cui CY ... T Griggs B Srivastava AK Schlessinger D Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential ... T Griggs B Srivastava AK Schlessinger D Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential ...

Tópico(s): Proteoglycans and glycosaminoglycans research

2005 - Elsevier BV | American Journal Of Pathology

Artigo Revisado por pares

R. Timothy Miller, Serrine S. Lau, Terrence J. Monks,

α-Methyldopamine (α-MeDA) is a metabolite of the serotonergic neurotoxicants 3,4-(±)-(methylenedioxy)amphetamine (MDA) and 3,4-(±)-(methylenedioxy)methamphetamine (MDMA). α-MeDA readily oxidizes, and in the presence of glutathione ( ... yl)-α-methyldopamine [5-(glutathion-S-yl)-α-MeDA]. Since GSH conjugates of many polyphenols are biologically ( ... the role of 5-(glutathion-S-yl)-α-MeDA in the acute and long-term neurochemical changes ... icv) administration of 5-(glutathion-S-yl)-α-MeDA (720 nmol) to male Sprague-Dawley rats produced ...

Tópico(s): Mast cells and histamine

1996 - American Chemical Society | Chemical Research in Toxicology

Jornais Acesso aberto

Thomas Bedding, E. W. Foxlde, Geo. W. Valentine, George Fernau, J. Leisk, P. Everitt, Philip E. B. Jourdain, Alex Snaid, Edward Dunmore, Chapman Jones, Wilfred Emery, S. Herbert Fry, Alfred Watkins, W. Thomas, Major C. Gardner Vatcher, G. F. Ashley, Osborn Thornbery, Theodore Brown, J. H. Wileman, Albert Levy, T. Stokoe, Frederick Henry Varley, Rev. J. Carter Browne, Hector MacLean, J. A. Reid, J. H. Smith, J. Dormer, P. J. Slater, A. Lockett, R. A. Hamblin, W. E. Hellawell, Major C. Gardner Vatcher, Geo. H. Dunmore, F. J. Mortimer, Rev. B. Holland, W. Girling, H. J. Channon, W. T. Wilkinson, Rev. S. Whittell Key, J. A. Reid, William Fleming, George Bankart, J. A. Randall, J. McIntosh, C. T. Sutton, J. Dormer, W. Hampson, Richard Thirsk, Wilford F. Field, S. E. Kelf, C. H. Bothamley, Edmund J. Mills, J. Rees, C. Welborne Piper, Allan Blair, A. L. Henderson, Howard Farmer, Henry O. Klein, G. T. Harris, William Brooks, C. W. Babbage, James Reuel Smith, E. J. Steer, J. Tilfor, Joseph Barker, R. J. Bailey, J. H. Baldock, F. H. Glew, J. A. C. Murray, J. T. Hackett, Henry W. Bennett, Geo. Ewing, Henry W. Bennett, Charles Louis Hett, J. Pike, Henry Cooper, R. Zahr, Matthew Wilson, Edgar Scamell, W. B. Ferguson, Dr. M. Andresen,

... Goerz-Anschutz Folding Camera, Lantern Apparatus Department, 'The Meda', The "Atlas" Enameller, The Barnet Book of Photography, ...

1901 - Gale Group | NCCO Photography

Artigo Revisado por pares

Márcia Carvalho, Fernando Remião, Nuno Milhazes, Fernanda Borges, Eduarda Fernandes, Maria do Céu Monteiro, Maria José Gonçalves, Vítor Seabra, Francisco Amado, Félix Carvalho, Maria de Lourdes Bastos,

... MDA), N-methyl-α-methyldopamine (N-Me-α-MeDA), and α-methyldopamine (α-MeDA) using freshly isolated adult rat cardiomyocytes. The cell ... and 1.6 mM for 4 h. α-MeDA, N-Me-α-MeDA, and their respective aminochromes (oxidation products) were quantified ... In contrast, their catechol metabolites N-Me-α-MeDA and α-MeDA induced significant toxicity in rat cardiomyocytes. The toxic ... to conjugation of GSH with N-Me-α-MeDA and α-MeDA, sustained increase of intracellular Ca2+ levels, ATP depletion, ... enzyme activities. The oxidation of N-Me-α-MeDA and α-MeDA into the toxic compounds N- ...

Tópico(s): Neurotransmitter Receptor Influence on Behavior

2004 - American Chemical Society | Chemical Research in Toxicology

Jornais Acesso aberto

John Dugdale, M, Michael Prescott, Patrick French, Barney Spender, Robin Williams, Barbara Hall, Judith O'Reilly Education Correspondent, Christopher Morgan Religious Affairs Correspondent, France Hachette, Andrew Warshaw, Geoff Maxted, W H, William Josling, Emma Payne, John Peter, Pam Barrett, Emma Moore, Derek Hodgson, Woody Harrelson, Meda Amor, Robert Sandail, John Jay, Susan d'Arcy, Ruud Gullit, Emine Saner, Frank Whitford, Mathew Loup, Ivo Tennant, Brian Porter, Ferdinand Mount, Addison de Witt, Sally Payne, David Smith, Edin Hamzic, Gary Lambert, Chris Dignan, Nick Pitt, Donu Kogbara, William Green, Neil Wormald, Andrew Sullivan, Clive Davis, Stephen Grey, Mary Wilson, Stephen Vines, Edward Platt, Geordie Greig, Tony Allen-Mills, Simon Wilde, Gwilym Gibbons, John McKeown, Anthony Sattin, Susan d'ARCY, Robert Winnett, Peter Wilson, Roger Anderson, Julian Barnes, Maurice Taylor, David Dougill, Philip Flaxton, D R, Philip Kingsley, Elliott Smith, Thrasy Petropoulos, H C, Sarah Toyne, David Hewson, David Maguiree, Marian Martin, Tania Alexander, Chris Hastings, Harvey Porlock, Yvonne Ridley, Jonathon Carr-Brown, Hugh Canning, David Caims, Margarette Driscoll, Jeremy Clarkson, Stewart Lee, Edward Porter, Peter Conradi, G T, Louise Taylor, Christine Griffiths, J T, Professor George Kerya, Michael Jones, Peter Millar, R N P, Rev Nancy Lane, George Perry, David Shaw, Andrew Barr, Kevin Connolly, Robin Marlar, Shelley von Strunckel, Paul Nuki Consumer Affairs Correspondent, Christine Toomey, Le Bossue, Wesley McKeown, Rev Andrew de Berry, Paul Ham, Thierry Oberle, Sue Lawrence, Gerald Kaufman, Kerry Addleton, Paul Driver, Garth Pearce, Sue Fox, Maeve Sheehan, Nicholas Hellen, Sarah Bradford, Richard England, Ian Hawkey, Ian Chadband, Christopher Morgan, Alicia Wyllie, Michael Prescott Chief Political Correspondent, Kirstie Hamilton, Margaret Blakeney, Tom Shone, Sarah Gracie, Mark Edwards, Susan Clark, Stephen Amidon, Mark Austin, David Lawrenson, Nicholas Rufford Home Affairs Editor, Malcolm Gloak, Phil Baker, Michael Riding, John Harlow Arts Correspondent, Don Johnson, Kay Macnicol, Shelley Long, John Updike, Thomas Pakenham, Howard Byrom, Raymond Keene, John Karter, Stanley Stewart, Cosmo Landesman, Zoe Brennan, Andrew Roberts, Marie Colvin, Debbie Hill, Diana Wright, Richard Branson Chairman, N B, Alan Malcomson, Helen Hawkins, Rebecca Tanqueray, Stephen Jones, Bishop Michael Marshall, Laurel Ives, Richard Evans, Pete McCarthy, Natalie Graham, Andrew Smith, Paul Nuki, Ros Belford, Caroline Donald, Martin Searby, Keith Wheatley, Claire Oldfield, David Walsh, La Lisa Brinkworth, Rasselas, Trevor Lewis, Ben Pimlott, Lisa Sykes, Anthony Cheetham's, John Ayres, Ron Clarke, Christopher Goodwin, Paul Kavanagh, Mark Prigg, Mrs K Kelland, Norman Stone, Roland White, Garth Alexander, Anne-Marie, Alex Fortune, Tim Brown, Andrew Lorenz Business Editor, Judith O'Reilly, Mark Franchetti, Ray Hutton, George Greig, James Hampton, Peter Watts, Ricky Dalton, Paul Bacon, Tara Palmer-Tomkinson, Stephen Roach, Michael Sheridan, K Stott, Susan Raven, Margaret Walters, Erica Brown, John Harlow, Matthew Lynn, Godfrey Smith, Peter Warburton, Donald Macgillivray, Michael Hodges, J A, John Waples, Terry Murden, Arthur Malu-Malu, A A Gill, Matthew Campbell, Brian Glanville, John Carey, Elizabeth Finnis, David Hutcheon, Cherry Norton Social Affairs Correspondent, Pleter de Hooch, Norma King, Stephen Pettitt, Robert Johnston, Jonathan Carr-Brown, Trushar Barot, Peter, Sally Kinnes, Andrew Lorenz, Delshad Karanjia, Naomi Caine, Liam Clarke, David Wickers, Roger Dobson, Nicholas Hellen Media Correspondent, Joe Lovejoy, Mark Porter, Ray Perry, Rupert Steiner, Rt Rev Lord Coggan, Chris Lightbown, Jonathan Futrell, Ali Stewart, Bruce Willis, Brian Pendreigh, David Caruso, David Parsley, Zoe Winterson, David Smith Economics Editor, Tom Deveson, Simon Trump, Zoe Linkson, Anthony Howard, Joeb Salzmann, Bob Dwyer, Nicholas Kenyon, Stephen Boyd, Kingston Smith, Dan Pearson, Boris Schapiro, Adam Parsons, Aminul Hoque,

Contents Blunkett lays down bedtime law for children Russia crisis threatens world slump Economists fear risk to euro Labour donors trigger cash-for-favours ...

1998 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Ludovic Wiszniewski, Alain Limat, Jean‐Hilaire Saurat, Paolo Meda, Denis Salomon,

... S. Chanson M. Saurat J.H. Spray D. Meda P. Gap-junction proteins and communication in human ... S. Chanson M. Saurat J.H. Spray D. Meda P. Gap-junction proteins and communication in human ... S. Chanson M. Saurat J.H. Spray D. Meda P. Gap-junction proteins and communication in human ... 1997Masgrau-Peya E. Salomon D. Saurat J.H. Meda P. In Vivo Modulation of Connexins 43 and ... 1998Labarthe M.P. Bosco D. Saurat J.H. Meda P. Salomon D. Upregulation of connexin 26 between ... 1997Masgrau-Peya E. Salomon D. Saurat J.H. Meda P. In Vivo Modulation of Connexins 43 and ...

Tópico(s): Heat shock proteins research

2000 - Elsevier BV | Journal of Investigative Dermatology

Artigo Revisado por pares

Marc Chanson, Patrice Mollard, Paolo Meda, Susanne Suter, Habo J. Jongsma,

... Scopus (52) Google Scholar, 17Chanson M. Orci L. Meda P. Am. J. Physiol. 1991; 261: G28-G36PubMed ... M. Bruzzone R. Spray D.C. Regazzi R. Meda P. Am. J. Physiol. 1988; 255: C699-C704Crossref ... Scopus (52) Google Scholar, 17Chanson M. Orci L. Meda P. Am. J. Physiol. 1991; 261: G28-G36PubMed ... mediates this effect is not known (38Chanson M. Meda P. Hall J.E. Zampighi G.A. Davis ... Scholar), also prevents ACh-induced uncoupling (38Chanson M. Meda P. Hall J.E. Zampighi G.A. Davis ... of pancreatic acinar cells (17Chanson M. Orci L. Meda P. Am. J. Physiol. 1991; 261: G28-G36PubMed ...

Tópico(s): Neuroscience and Neuropharmacology Research

1999 - Elsevier BV | Journal of Biological Chemistry

Artigo Revisado por pares

Fengju Bai, Serrine S. Lau, Terrence J. Monks,

... identity of which remains unclear. alpha-Methyldopamine (alpha-MeDA) is a major metabolite of both MDA and ... methyldopamine [2, 5-bis(glutathion-S-yl)-alpha-MeDA] causes decreases in serotonin concentrations in the striatum, ... yl)-alpha-methyldopamine [5-(glutathion-S-yl)-alpha-MeDA] and 5-(N-acetylcystein-S-yl)-alpha-methyldopamine [5-(N-acetylcystein-S-yl)-alpha-MeDA] produce neurobehavioral changes similar to those seen with ... intracortical administration of 5-(glutathion-S-yl)-alpha-MeDA (4 x 200 or 4 x 400 nmol), ...

Tópico(s): Neurotransmitter Receptor Influence on Behavior

1999 - American Chemical Society | Chemical Research in Toxicology

Artigo Revisado por pares

Márcia Carvalho, Fernando Remião, Nuno Milhazes, Fernanda Borges, Eduarda Fernandes, Félix Carvalho, Maria de Lourdes Bastos,

... metabolites, N-methyl-α-methyldopamine (N-Me-α-MeDA) and (2) to investigate the ability of antioxidants, ... l-cysteine (NAC), to prevent N-Me-α-MeDA-induced toxic injury, using freshly isolated rat hepatocytes. ... were incubated with MDMA or N-Me-α-MeDA in the final concentrations of 0.1, 0. ... treatment with 1.6 mM N-Me-α-MeDA for 3 h (throughout this incubation period the ... GPX, and GST. In contrast, N-Me-α-MeDA was shown to induce not only a concentration- ... and GSH depletion induced by N-Me-α-MeDA. The results provide evidence that MDMA and its ...

Tópico(s): Aldose Reductase and Taurine

2004 - Elsevier BV | Toxicology

Artigo Acesso aberto Revisado por pares

Chris A. Learn, Steven B. Mizel, Charles E. McCall,

... support of this notion, Cassatella (26.Cassatella M. Meda L. Gasperini S. Calzetti F. Bonora S. J. ... pro- and anti-inflammatory genes (26.Cassatella M. Meda L. Gasperini S. Calzetti F. Bonora S. J. ... COX-2 and IL-1 (26.Cassatella M. Meda L. Gasperini S. Calzetti F. Bonora S. J. ... support of this notion, Cassatella (26.Cassatella M. Meda L. Gasperini S. Calzetti F. Bonora S. J. ... pro- and anti-inflammatory genes (26.Cassatella M. Meda L. Gasperini S. Calzetti F. Bonora S. J. ... COX-2 and IL-1 (26.Cassatella M. Meda L. Gasperini S. Calzetti F. Bonora S. J. ...

Tópico(s): S100 Proteins and Annexins

2000 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Marie-Pierre Labarthe, Jean‐Hilaire Saurat, Denis Salomon, Domenico Bosco, Paolo Meda,

... Salomon et al., 1988Salomon D. Saurat J.-H. Meda P. Cell-to-cell communication within intact human ... Chanson M. Saurat J.-H. Spray D.C. Meda P. Gap junction proteins and communication in human ... 1997Masgrau-peya E. Salomon D. Saurat J.-H. Meda P. In vivo modulation of connexins 43 and ... sense probes were synthesized by in vitro transcription (Meda et al., 1993Meda P. Pepper M. Traub O. ... Chanson M. Saurat J.-H. Spray D.C. Meda P. Gap junction proteins and communication in human ... 1997Masgrau-peya E. Salomon D. Saurat J.-H. Meda P. In vivo modulation of connexins 43 and ...

Tópico(s): Bacillus and Francisella bacterial research

1998 - Elsevier BV | Journal of Investigative Dermatology

Carta Acesso aberto Revisado por pares

Nur Zeynep Güngör, Joshua P. Johansen,

In this issue of Neuron, Meda et al., 2019Meda K.S. Patel T. Braz J.M. Malik R. Turner M.L. Seifikar H. Basbaum A.I. Sohal ... promote aversive learning. In this issue of Neuron, Meda et al., 2019Meda K.S. Patel T. Braz ... are altered by chronic pain. The study by Meda and colleagues in this issue of Neuron (Meda et al., 2019Meda K.S. Patel T. Braz ... Scopus (1348) Google Scholar). In the present study, Meda et al., 2019Meda K.S. Patel T. Braz ... role in pain-free animals is less clear. Meda et al., 2019Meda K.S. Patel T. Braz ...

Tópico(s): Memory and Neural Mechanisms

2019 - Cell Press | Neuron

Artigo Revisado por pares

João Paulo Capela, Cristina Alves de Macedo, Paula S. Branco, Luı́sa M. Ferreira, Ana M. Lobo, Eduarda Fernandes, Fernando Remião, Maria de Lourdes Bastos, Ulrich Dirnagl, Andreas Meisel, Félix Carvalho,

... to N-methyl-alpha-methyldopamine (N-Me-alpha-MeDA) and alpha-methyldopamine (alpha-MeDA), respectively, which are both catechols that can undergo ... MDMA metabolites, obtained by synthesis: N-Me-alpha-MeDA, alpha-MeDA and their correspondent GSH and NAC adducts. The ... catechols. On the other hand, N-Me-alpha-MeDA and alpha-MeDA are more neurotoxic than MDMA. GSH and NAC conjugates of N-Me-alpha-MeDA and alpha-MeDA induced a concentration dependent delayed neuronal death, accompanied ...

Tópico(s): Psychedelics and Drug Studies

2007 - Elsevier BV | Neuroscience