Jon Ashworth, Edward Gorman, Sailing Correspondent, Robert Cole, Andrew Pierce, Chris Ward, Grace Bradberry, Sarah Potter, George Pendle, Claire McDonald, Mark Souster, Richard Hobson, David Rhys Jones, Clare Neylan, Raymond Snoddy, Media Editor, Jane Bolton, Caroline Merrell, Banking Correspondent, Norman De Mesquita, James Bone, Rachel Campbell-Johnston, Alison Kervin, Alexandra Frean Social Affairs Correspondent, Mary Wilson, Carl Mortished, David Robinson and Perry Cleveland-Peck, Roland Watson, Chief Political Correspondent, Heather Neill, Kevin Eason, Joe Joseph, Judy Jones, Valerie Elliott Countryside Editor, David McVay, John O'leary Education Editor, John Melotte, John Bull, Dominic Walsh, Debra Craine, Alasdair Reid, Gary Jacob, Raymond Keene Chess Correspondent, Tim Reid, Michael Harvey, Libby Purves, Matthew Parris Political Sketch, Anita Chaudhuri, Alan Hamilton, Robin Young, Oliver Wright, Mark Inglefield, John O'Leary, James Landale Political Correspondent, Geoffrey Wheatcroft, Harold Shipman, Charles Bremner, Katherine Bergen, John Kavanagh, Peter Barnard, David Charter, Ros Drinkwater, Patience Wheatcroft Business Editor, Paula Hawkins, Vanora Bennett, Robert Cole City Correspondent, Paul Armstrong, Richard Cork, David Lister, Tom Baldwin, Peter Woodman, Valerier Elliott, Consumer Editor, Karen Homer, Rob Wright, Stephen Wood, John MacCain, Raymond Keene, Clive Mathieson, Alan Clark, Matt Dickinson, Nigel Cliff, Nigel Hawkes, Sally Gray, Melissa Kite, Chris Ayres Media Business Correspondent, David Powell, Athletics Correspondent, Richard Owen, Simon Barnes Sports Feature Writer of the Year, Tony Patrick and Louise Godfrey, Gavin Lumsden, Insurance Correspondent, Roger Boyes, Fenton Bresler, Oliver August, Ian Murray Medical Correspondent, Sally Morris, David Hands Rugby Correspondent, Martin Fletcher European Correspondent, Anne Ashworth, Nick Szczepanik, Giles Whittell, Christopher Walker, Simon De Bruxelles, Janine di Giovannl, Alex O'Connell, Craig Lord, Anjana Ahuja, Chris McGrath, Caitlin Moran, Peter Riddell, Ben MacIntyre, Richard Beeston, Philip Webster, Bruce Chariton, Simon Jenkins, Lea Paterson, Tim Jones, Martin Waller, Michael Horsnell, Perry Cleveland-Peck, Alan Coren, Ian S. Menzies, Benedict Nightingale, Alice Miles, Alex O'connell, Adam Sherwin, Allan Hall, Robert Whymant, John Goodbody, Sports News Correspondent, Anthony Howard, Fraser Nelson Retail Correspondent, Vincent Van Gogh, Lea Paterson, Economics Correspondent, Christopher Irvine, Christine Buckley, Industrial Correspondent,
... Unit Managers LTD Sell Buy Fleming Private Fund MGMT LTD The Times Unit Trust Information Service Fidelity ... Fund Managers LTD Sell Buy Rathbone Unit Trust MGMT LTD Scottish Widows Fund MGMT Sell Buy Tribunal ...
2000 - Gale Group | TDA
... indicate age in California ground squirrels. J. Wildl. Mgmt, 31, 836–839. Banfield, A. W. F. (1955) ... caribou antler pedicels for age determination. J. Wildl. Mgmt, 24, 99–102. Barrier, M. J. & Barkalow, F. ... aging gray squirrels in winter pelage. J. Wildl. Mgmt, 31, 715–719. Beale. D. M. (1962) Growth ... relation to age in fox squirrels. J. Wildl. Mgmt, 26, 208–211. Berry, R. J. & Truslove, G. ... in the black tailed jack rabbit. J. Wildl. Mgmt, 33, 159–164. Connolly, G. E., Dudziński, M. ... black tailed deer and mule deer. J. Wildl. Mgmt, 33, 701–704. Crowcroft, P. (1957) The Life ...
Tópico(s): Bat Biology and Ecology Studies
1972 - Wiley | Mammal Review
Directory of Open Access Journals (DOAJ)
Giles Tremlett, Adrian Lee and Daniel McGrory, Raymond Snoddy Media Editor, Joanna Hunter, Matthew Syed, Grace Bradberry, Richard Beeston and Zahid Hussain, Magnus Linklater, Richard Hobson, Robert Lea, Caroline Merrell, Banking Correspondent, Michael Binyon, Joanna Bale, Melissa Kite Parliamentary Reports, Angela Court, John Godbody, Ian Cundell, Kenneth Morgan, James Landale, Political Correspondent, Tony Patrick, Kevin Eason, Andrew Pierce and David Lister, Joe Joseph, Antonia Senior, Martin Fletcher, Pat Gibson, Mehrdad Khonsari, Seweryn Chomet, Tony Geragthy, Arthur Leathley, Aviation Correspondent, Dominic Walsh, John Monks, Shirley English, Raymond Keene Chess Correspondent, Dr Jane Collins, Ruth Gledhill Religion Correspondent, K. J. Chapman, Libby Purves, Alex Kane, Robin Young, Mark Inglefield, Matt Sims, Make. O'connor Director, John O'Leary, Daniel Lee, Dominic Kennedy and Adam Sage, Mike Bradley, Alix Ramsay, Tennis Correspondent, David Hands, Zahid Hussain and Arthur Leathery, Karyn Woods, David Jones, Peter Barnard, David Charter, Edward Gorman, Derwent May, Russell Kempson, Michael Evans and Stewart Tendler, Daniel McGrory, Edward Fennell, David Lister, John Hopkins, Tom Baldwin and Valrie Elliott, Ann Treneman, Rob Wright, Adrian Zuckerman, Stephen Wood, Richard Duce and Adam Fresco, Adam Jones, Martin Ball, Adam Sage, Clive Mathieson, Helen Johnstone and Olive Wright, Paul Wilkinson, R. L. Pomeroy, Harry Mawdsley, Carl Mortished, International Business Editor, Deborah Brett, Patrick Nairne, Roger Boyes, Oliver August, Ian Murray Medical Correspondent, Roy Swanston, Richard Duce, Paul Wilkinson and Frances Gibb, Nick Szczepanik, Dominic Kennedy, Giles Whittell, Philip Webster Political Editor, A. J. Wilcock, Christopher Walker, Rosalind Cameron-Mowatt, Jane Collins, Matthew Parris, Donald Cross, Alex Swanson, George Caulkin, Lord Russell, Moira Petty, Walter Gammie, Peter Riddell, Ben MacIntyre, Ian Brodie, Martin Waller, Perry Cleveland-Peck, Nigel Hawkes Science Editor, Carl Mortished International Business Editor, Fran Littlewood, Sam Rush and Fellcity Reeve, Benedict Nightingale, Frances Gibb, Legal Editor, Richard Morrison, James Doran, City Correspondent, Frances Gibb, Sam Kiley, David Powell, Adam Sherwin, Tom Baldwin Deputy Political Editor, Allan Hall, Robert Whymant, Peter Hemsworth, Alan Lee Racing Correspondent, David Hands, Rugby Correspondent, Lea Paterson, Economics Correspondent, Christopher Irvine, Christine Buckley, Industrial Correspondent,
... Unit Managers Ltd No Title Fleming Private Fund Mgmt Ltd No Title Hsbc Investment Funds (Uk) Ltd ... Fund Managers Ltd No Title Rathbone Unit Trust Mgmt Ltd Scottish Widows Fund Mgmt Times 3 John ...
2000 - Gale Group | TDA
Russell O. Pieper, Bernard W. Futscher, Qing Dong, Thomas M. Ellis, Leonard C. Erickson,
... accepting suicide enzyme O-6-methylguanine DNA methyltransferase (MGMT). Approximately 25% of cell lines derived from human ... described as Mer-. Recent cloning of the human MGMT cDNA (Tano, K.; Shiota, S.; Collier, J.; Foote, ... Using the polymerase chain reaction (PCR) technique, an MGMT cDNA probe based on the published sequence was ... to analyze the presence and expression of the MGMT gene in two Mer+ and four Mer- lines, ... six cell lines contained a relatively nonamplified, nonrearranged MGMT gene, Mer- lines contained levels of MGMT mRNA ...
Tópico(s): Glioma Diagnosis and Treatment
1990 - Pergamon Press | Cancer Communications
Phil Yates, Giles Tremlett, Edward Gorman, Sailing Correspondent, Raymond Snoddy Media Editor, Adrian Room, Helen Johnstone, Joanna Hunter, Robert Cole, Michael Aylwin, Chris Ward, Sally Brock, Grace Bradberry, Frances Gibb Legal Editor, Ian Brodie and James Bone, Simon Barnes, George Pendle, Claire McDonald, David Rhys Jones, Richard Hobson, Raymond Snoddy, Media Editor, Trevor Openshaw, D. R. Myddelton, Tessa Jowell, Philip Howard, Michael Spicer Chairman, Michael Binyon, James Bone, Elizabeth Judge, Brian Barder, Rosalind Renshaw, Ian Cundell, Oliver Holt Football Correspondent, Carl Mortished, James Landale, Political Correspondent, Michael Evans, Defence Editor, Nick Nuttall, Environment Correspondent, Sir Trevor Lloyd-Hughes, M. B. Simons, Fraser Nelson, Retail Correspondent, Joe Joseph, Louise Godfrey, Ian Murray and Paul Wilkinson, Valerie Elliott Countryside Editor, David McVay, Stewart Tendler Crime Correspondent, Dominic Walsh, Raymond Keene Chess Correspondent, Alix Ramsay Tennis Correspondent, Michael Harvey, Jack Ozanne, Michael Mulvihill, Clare Thompson, Roderick A. Smith, Anita Chaudhuri, Ana Urena, Heather Nicholson, Alan Hamilton, Oliver Wright, Mark Inglefield, Rodney Milnes, Alice Lagnado, Amy Anderson, Charles Bremner, Jill Sherman, Whitehall Editor, Katherine Bergen, John Kavanagh, Helen Rumbelow, Rae McDonald, Peter Barnard, David Charter, Caroline Merrell Banking Correspondent, Paula Hawkins, Russell Kempson, Sue Fox, Nigel Williamson, Paul Armstrong, Richard Cork, Paul Durman, David Lister, Lisa Armstrong, Marit Hargie, Michael Dynes, Africa Correspondent, Barry Millington, Simon de Bruxelles, Stephen Wood, Dalya Alberge, Arts Correspondent, Adam Jones, Ben MacIntyre and Whitworth, Raymond Keene, V. M. E. Hyland, David Robinson, Clive Mathieson, John Russell Taylor, Matt Dickinson, Nigel Cliff, Roger L. Davies, Nigel Hawkes, Caroline Merrell, Carl Mortished, International Business Editor, Melissa Kite, Roy Dean, Damian Whitworth, Russell Jenkins and Shirley English, Ben MacIntyr and Damian Whitworth, Fenton Bresler, Oliver August, Philip Webster, Political Editor, Robert Cole, City Correspondent, Susie Steiner and Roland Watson, David Hands Rugby Correspondent, Glen Owen, Richard Duce, Anne Ashworth, Joanna Pitman, James Doran, Stephen Haseler, James Pringle, Simon De Bruxelles, Gwenda Brophy, Deborah King, Matthew Parris, Anjana Ahuja, George Caulkin, Alan Lee, David Foot, Peter Riddell, Ben MacIntyre, Mark Perryman, Barbara Hamilton, Faith Glasgow, Ian Brodie, John Wilson, Richard Beeston Diplomatic Editor, Michael Dynes, E. ATKIN(Managing Director), Martin Waller, Elizabeth Cowley, Chris Ayres, Barry Wigmore, R. L. T. Burges, Joanna Bale, Fiona Fleck and Giles Tremlett, Trevor Kennea, Richard Morrison, Alice Miles, Tom Baldwin Deputy Political Editor, Alasdair Murray, Allan Hall, Alan Lee Racing Correspondent, Gavin Smithers, Anthony Howard, Jan Raath, Fraser Nelson Retail Correspondent, Avril Munson, Roland Watson and Tom Baldwin, Christine Buckley, Industrial Correspondent, Arthur Leathley Transport Correspondent,
... Title Cis Unit Mahagers Ltd Fleming Private Fund Mgmt Ltd No Title Mercury Fund Mahagers Ltd No ... com No title No Title Rathbone Unit Trust Mgmt Ltd Scottish Widows' Fund Mgmt No Title Italians ...
2000 - Gale Group | TDA
... have a range of O6-methylguanine-DNA methyltransferase (MGMT) activities. PBLs from some individuals may have almost no MGMT activity. Such individuals have most often been subject ... subjects by Epstein-Barr virus (EBV) transformation have MGMT activities which are in general somewhat higher than ... which they derive. Such cultures are therefore generally MGMT-positive. Only in rare cases, and generally from patients with low MGMT activity, are freshly obtained lines with very low ... There is however a 4-fold range of MGMT activity over which multiple lines derived from the ...
Tópico(s): DNA Repair Mechanisms
1990 - Elsevier BV | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Ed Potten, Brendan Murphy, David Madden, Alan McLintock, Raymond Snoddy Media Editor, Martin Fletcher and Gillian Harris, Helen Johnstone, Catherine Philip, Nick Nuttall, Alun Morris, Robert Cole, John White, Sally Brock, Alexandra Frean, James Moore, Carl Mortished and Adam Jones, Paul Armstrong and James Moore, Magnus Linklater, Frank ALLAUN(President Labour Action for Peace), Paul Hoggart, Richard Hobson, Ivo Tennant, Dominic Kennedy and Damian Whitworth, Michael Evans Defence Editor, Philip Howard, Carol Midgley, Jeremy Kingston, James Bone, Ramblin Dave Sinclair, Alisdair Pugh and Way, Clive Davis, Ray Kennedy and Nigel Hawkes, Peter BREAKEY(Senior Lecturer), Barbara Ellen, James Glyn, Kevin Eason, Geoff Brown, Jim Prior, Vice-President, Raymond Snoddy, Joe Joseph, Giles Coren, Andrew Norfolk, John Thicknesse, Christ McGrath, Pat Gibson, Paul Fitzpatrick, John Stevens Leader, David McVay, John Bryant, Philip Webster and Tom Baldwin, Cornelius Lysaght, Thrasy Petropoulos, David Charter Education Correspondent, Shirley English, Michael Harvey, Tim Reid, Mary Ann Siegbart, Nick Nuttall Technology Correspondent, Stephen Farrell, Oliver Wright, Mark Inglefield, Jenny MacArthur, Alice Lagnado, Tom Baldwin and Alexandra Frean, John O'Leary, James Landale Political Correspondent, Helen Rumbelow Medical Reporter, Jason Allardyce Scottish Political Reporter, Mike Bradley, Charles Bremner, Michael Leapman, Helen Rumbelow, Anthea Lawson, David Charter, Tim Teeman, Caroline Merrell Banking Correspondent, James Doran City Correspondent, John CURTISS(President British Berlin Airlift Association), Paul Armstrong, Richard Cork, Paul Sexton, Simon de Bruxelles, Geoffrey Dean, Stephen Wood, Colin BULLEN(Member NEC Campaign for an Indepent Britain), Adam Jones, Paul Peachey, Stuart Nicholson, Richard Owen and Helen Johnstone, Ruth Lea, Peter Davalle, Clive Mathieson, David Robinson, Christine Buckley Industrial Editor, Linda McDougall, Melissa Kite, Geogory Damaine, Christopher Martin-Jenkins Chief Cricket Correspondent, Damian Whitworth, Damian Whitworth and Daminic Kennedy, Oliver August, Nick Hasell, Hettie Judah, David Hands Rugby Correspondent, Lea Paterson and David Lister, Jennifer O'Neill, Adam Fresco, John Allison, Ramsey Zarifeh, Tony Goldman, Michael McMahon, James Doran, Jane Shilling, Brian MacArthur, Alex O'Connell, Mel Webb, Graham Searjeant Financial Editor, A. J. Menzies, Maggie Walker, Russell Jenkins, John Shaw, J. A. D. Ewart, Michael Austin, Caitlin Moran, Corinna Bronitt-Kitchingham, Ben MacIntyre, Richard Beeston, James Bone and Michael Evans, John Julius Norwich, Martin Waller, Chris Ayres, Gillian Harris, Carl Mortished International Business Editor, Laura Peek, Dr Thomas Stuttaford, Dick Scruton, Richard Morrison, Jack Bailey, Adam Sherwin, Tom Baldwin Deputy Political Editor, Allan Hall, Alan Lee Racing Correspondent, Fraser Nelson Retail Correspondent, Jane Shillings,
... Acm Investments Ltd No Title Fleming Private Fund Mgmt Ltd No Title Hill Samuel Unit Tst Mgrs ... Unit Trust MGRS No Title Murray Johnstone UT Mgmt No Title Royal & Sun Alliance UT Mgmt Ltd ...
2000 - Gale Group | TDA
Marija Balić, Martin Pichler, Jasmin Strutz, Ellen Heitzer, Christoph Ausch, Hellmut Samonigg, Richard J. Côté, Nadia Dandachi,
... evaluated HRM assays for O6-methylguanine-DNA methyltransferase (MGMT) and adenomatous polyposis coli (APC) promoter methylation on ... we used these assays for the analysis of MGMT and APC promoter methylation in a subset of ... tumor specimens. All samples with promoter methylation of MGMT or APC and randomly selected samples without promoter ... All results generated by HRM were validated with MGMT and APC MethyLight assays. APC and MGMT promoter methylation data were consistent and reproducible throughout ...
Tópico(s): Epigenetics and DNA Methylation
2009 - Elsevier BV | Journal of Molecular Diagnostics
Jon Ashworth, Raymond Snoddy Media Editor, Stephen Shaw, Helen Johnstone, Nick Nuttall Environment Correspondent, Martin Elliott, Robert Cole, Sally Brock, Graham Kelly, James Moore, Patricia Davies, Sarah Potter, Frances Gibb Legal Editor, Simon Barnes, Paul Hoggart, Richard Hobson, Ivo Tennant, Robert Lea, Salvador Dali, David Horchover, Philip Howard, Boyd Farrow, Angela Devlin, Jeremy Kingston, Nigel Broadbent, Anne Robinson, Barbara Ellen, Adam Boulton, Jeremy Whittle, Kevin Eason, Wendy Holden, Raymond Snoddy, Philip Webster and Christopher Walker, Giles Coren, Joe Joseph, Antonia Senior, Martin Fletcher, Pat Gibson, Valerie Elliott Countryside Editor, David McVay, Rupert Cox, David Charter Education Correspondent, Robert Barlow, Dominic Walsh, Mike Pattenden, Geoffrey M. Beresford Hartwell, Alix Ramsay Tennis Correspondent, Dominic Searle and Daniel McGrory, Tim Reid, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Michael Mulvihill, Richard Ford Home Correspondent, Robin Young, Oliver Wright, Mark Inglefield, Helen Rumbelow Medical Reporter, Robert Walls, Mike Bradley, Charles Bremner, John O'shea (Director), Helen Rumbelow, Peter Barnard, Caroline Merrell Banking Correspondent, Jasper Gerard, Chris Ayres Media Business Editor, Russell Kempson, Philip R. Matthews (Chairman), Paul Armstrong, Paul McCann, Matt Dickinson Football Correspondent, Simon de Bruxelles, John Hopkins Golf Correspondent, Geoffrey Dean, Clive Mathieson and James Doran, Stephen Wood, James Doran and Clive Mathieson, Paul Peachey, Stuart Nicholson, Raymond Keene, David Robinson, Clive Mathieson, Paul Wilkinson, Christine Buckley Industrial Editor, R. Wayne Carney, T. L. P. Watts, Rajnikant J. Mehta, Melissa Kite, Andrew Pierce and Richard Ford, Richard Owen, Michael Harvey and John Goodbody, Damian Whitworth, Clare Sterling, Christopher Martin-Jenkins Chief Cricket Correspondent, Roger Boyes, John Stern, Nick Hasell, cORNELLUS lYSAGHT, Philip August, Kim Willsher, David Hands Rugby Correspondent, Hettie Judah, Martin Fletcher European Correspondent, John Goodbody, Duke Ellington, Mary Ann Sieghart, Philip Webster Political Editor, Jane Shilling, Brian MacArthur, Alex O'Connell, Srikumar Sen Boxing Correspondent, Paul McCann Media Correspondent, Chris McGrath, Melissa Kite Political Reporter, Richard Ford and Roland Watson, Caitlin Moran, Michael Austin, Anthony Loyd, Peter Riddell, Ben MacIntyre, Christopher Ward and Richard Case…, Richard Beeston Diplomatic Editor, Michael Dynes, Chris Irvine, Richard Miles, David Sinclair, Simon Jenkins, Fraser Nelson, Tim Jones, David Ford, Martin Waller, Michael Horsnell, Chris Ayres, Clive Coen, Sophie Petit-Zeman, Benedict Nightingale, Valerie Grove, Tom Baldwin Deputy Political Editor, David Wellings, Patricia Bailey, Lea Paterson Economics Correspondent, Roland Watson Chief Political Correspondent, Patience Wheatcroft, Janine di Giovanni, John S. Porteous, Arthur Leathley Transport Correspondent,
... Times Unit Trust Information Service Fleming Private Fund Mgmt Ltd The Times Unit Trust Information Service Murray Johnstone Ut Mgmt The Times Unit Trust Information Service Hot Share ...
2000 - Gale Group | TDA
Emanuela Taioli, Camille Ragin, Xiaohong Wang, Jiangying Chen, Scott M. Langevin, Ashley R. Brown, Susanne M. Gollin, Seymour Garte, Robert W. Sobol,
... promoter methylation status of the DNA repair gene MGMT and the tumor suppressor genes CDKN2A and RASSF1 ... and correlated with survival and tumor recurrence. Quantitative MGMT methylation was also assessed. Results 29.6% of the tumors presented with MGMT methylation, 11.5% with CDKN2A methylation and 12.1% with RASSF1 methylation. MGMT promoter methylation was significantly associated with poorer overall ... free survival. No differences in methylation status of MGMT and RASSF1 with HPV infection, smoking or drinking ...
Tópico(s): Cancer-related molecular mechanisms research
2009 - BioMed Central | BMC Cancer
Jon Ashworth, Sally Staples, Raymond Snoddy Media Editor, Andrew Eames, David Adams, Helen Johnstone, Nick Nuttall Environment Correspondent, Alasdair Riley, Nick Nuttall, Robert Cole, Portia Colwell, Catherine Riley, Andrew Pierce, J. Johnson, Sally Brock, James Moore, Patricia Davies, Grace Bradberry, Jane MacQuitty, Simon Barnes, David Bowes, John Morgan, Paul Hoggart, Stephen Bragg, Sean Hardy, Richard Hobson, Ivo Tennant, Robert Lea, Douglas Friedli, Raymond Keen, Philip Howard, Richard Beeston Diplomatic Correspondent and Michael Hartnack, Alexandra Frean Social Affairs Correspondent, Elizabeth Judge, Leslie Fraser-Mitchell, Sharon Linnard, Nick Royle, Tony Patrick, Kevin Eason, Amon Cohen, Gerald Davies, Clare Stewart, Thunderer, Andrew Norfolk, John O'Leary Education Editor, Louise Godfrey, Antonia Senior, Conal Urquhart, Valerie Elliott Countryside Editor, Pat Gibson, John Clarke, Tom Baldwin and Dominic Kennedy, D. R., Steve Keenan, Dominic Walsh, Jerome Boyd Maunsell, Shirley English, Ruth Hunsley, Mike Pattenden, Alix Ramsay Tennis Correspondent, James and Monica Tickner, Tim Reid, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Jonathan Gornall, Jo Morris, Nicola Walters, Director, Alan Hamilton and Oliver Wright, T. P., A. P. Beaumont-Markland, Roland Watson, David Hands, P. B., Charles Bremner, Martin Symington, John Amaechi, Peter Barnard, Anthea Lawson, Tim Teeman, Nicholas Wapshott, Derwent May, James Hopkin, Kate Hilpern, Jasper Gerard, Russell Kempson, Paula Hawkins, Mary Gold, Daniel McGrory, David Webb, Paul Armstrong, Liz Jensen, Blake Pinnell, Stephen Anderton, June Osborne, Nicole Swengley, Amber Cowan, D. J. Pound, Sue Beenstock, Michael Theodoulou, Jill Sherman Whitehall Editor, John Hopkins Golf Correspondent, Geoffrey Dean, Rob Wright, Christina Koning, Rachael Jolley, Susie Steiner and Philip Webster, Arthur Leathley Aviation Correspondent, Marcus Binney, Raymond Keene, Adam Sage, David Robinson, Clive Mathieson, Matt Dickinson, Paul Wilkinson, Christine Buckley Industrial Editor, Meera Syal, David soward, Jeannette Hyde, Michael Evans and Michael Dynes, Min Cooper, Clive Petty, W. J. B. Chiltern plc, Roger Protz, Chris Ayres Media Business Correspondent, Jane Hughes, Richard Owen, Shane Warne, W. Wratten, Damian Whitworth, Stephen Pointon, Miranda McAllister, Anne Paterson, Roger Boyes, Emily Davies, Oliver August, John Stern, Dennis L. Bird, Clive Mathieson and Fraser Nelson, Nick Hasell, John Adams, Ashley Mote, John Sherlock, Dalya Alberge, David Hands Rugby Correspondent, Celestria Noel, Glen Owen, Lorne MacKillop, Martin Fletcher European Correspondent, Suzznnah Olivier, Linda Farmer, Karen Bradstock, Alex O'Connell, Tome Dunkley, Poonam Goel, Jennai Cox, Richard Miles Deputy Personal Finance Editor, Chris McGrath, Michael Austin, Alan Lee, Jane Owen, Ben MacIntyre, Helen Pridham, Christopher Reed, Graham Searjeant, David Sinclair, Fraser Nelson, Richard Miles, Tim Jones, Lauris Morgan-Griffiths, Martin Waller, Jason Cowley, Chris Ayres, Fran Littlewood, Mark Baldwin, Laura Peek, Irene Jones, Dr Thomas Stuttaford, Jill Crawshaw, Richard Morrison, David Powell, Tom Chesshyre, Valerie Grove, Tom Baldwin Deputy Political Editor, Lea Paterson Economics Correspondent, Sally Patten, Cath Urquhart Travel Editor, Fraser Nelson Retail Correspondent, Gill Hornby, Janine di Giovanni, Christopher Irvine, Susan Emmett, Arthur Leathley Transport Correspondent,
... Times Unit Turst Information Service Fleming Private Fund Mgmt LTD The Times Unit Turst Information Service Red ... Times Unit Trust Information Service Murray Johnstone Ut Mgmt The Times Unit Trust Information Service Royal & Sun ...
2000 - Gale Group | TDA
Michael Weller, Roger Stupp, Guido Reifenberger, Alba A. Brandes, Martin J. van den Bent, Wolfgang Wick, Monika E. Hegi,
The DNA repair enzymeO6-methylguanine-DNA methyltransferase (MGMT) antagonizes the effects of alkylating agents, and its expression is associated with resistance to cancer therapy based on these compounds. Weller et al. consider the prognostic and predictive value of MGMT gene silencing in gliomas and describe the assays that are commonly used to evaluate MGMT status, focusing particularly on MGMT promoter methylation, which is the key mechanism of ... The DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGMT) antagonizes the genotoxic effects of alkylating agents. MGMT ...
Tópico(s): Histone Deacetylase Inhibitors Research
2009 - Nature Portfolio | Nature Reviews Neurology
Andrew Pierce, Giles Browne, Patricia Davies, Roy Edey, Neil Bennett, Angus Nicol, Matt Wolf, Michael Binyon, Noel Goodwin, Lynne Truss, Carl Mortished, Simon Wilde, Heather Cope, Peter Hilditch, Bernard Levin, Martin Fletcher, Pat Gibson, Melvyn Marckus, City Editor, John Hopkins, Golf Correspondent, Vincent Malone, Raymond Keene Chess Correspondent, Rachel Kelly, David Adams, and Tom Rhodes, Andrew McIntyre, Lord Monson, Libby Purves, W. T. Rowland, Stuart Jones, Tennis Correspondent, Nicholas Watt, John O'Leary, John Young, Charles Bremner, David Guest, Sarah Bagnall, Philip Bassett, Industrial Editor, Brian Bagnall, Philip Bassett, Lindsay Cook, Gillian Bowditch, Geoffrey Wheeler, David Toop, Wolfgang Münchau, Victoria Davis, David Powell Athletics Correspondent, Peter Davalle, John Grigg, Frances Gibb, Legal Correspondent, Paul Wilkinson, Marianne Darch, Colin Narbrough World Trade Correspondent, Marcus Binney Architecture Correspondent, Richard Evans, Roger Boyes, Philip Webster, Political Editor, Rodney Hobson, David Hands Rugby Correspondent, Julian Muscat, Richard Duce, Martin Waller, Deputy City Editor, Christopher Thomas, Joanna Pitman, Ross Tieman Industrial Correspondent, Philip Bassett and Bill Frost, Geoffrey Hinton, Nick Nuttall, Technology Correspondent, Christopher Walker, Nicholas Watt Ireland Correspondent, Rob Hughes, Football Correspondent, Mel Webb, Craig Lord, Peter Atkinson, Alan Lee, Ben MacIntyre, Richard Beeston, Mick Hurrell, David Sinclair, Philip Pangalos, Tony Benn, Stephen Pettitt, Martin Waller, Nigel Hawkes Science Editor, Tom Rhodes, Mark Glover, Trevor Dannatt, Jack Bailey, David Powell, Martin Waller Deputy City Editor, John Phillips, Alan Jackson, Ross Tieman, Colin Campbell,
... Aib Unit Trust Managers Ltd Fleming Private Fund Mgmt Ltd No Title Granville Unit Tst Mgmt Ltd HSBC Unit Trust Mgmt Ltd No Title Mw Investment Managers Ltd 46 ...
1994 - Gale Group | TDA
Brett L. Carlson, Patrick T. Grogan, Ann C. Mladek, Mark A. Schroeder, Gaspar J. Kitange, Paul A. Decker, Caterina Giannini, Wenting Wu, Karla V. Ballman, C. David James, Jann N. Sarkaria,
... was significantly higher for O6-methylguanine-DNA methyltransferase (MGMT) methylated tumors versus unmethylated tumors following treatment with ... p = 0.47). In an analysis of variance, MGMT methylation status and p53 mutation status were significantly ... therapy, only a subset (5 of 11) of MGMT methylated tumors derived substantial additional benefit from combined therapy, while none of the MGMT unmethylated tumors did. Consistent with a true radiosensitizing ... significant survival benefit only in a subset of MGMT methylated tumors and provides superior antitumor activity relative ...
Tópico(s): Cancer Genomics and Diagnostics
2009 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Phil Yates, Raymond Snoddy Media Editor, A. H. MacKenzie, Joanna Hunter, Eve-Ann Prentice and Sean Hillen, Zahid Hussain, John Livitt, Adrian Lee, Richard Ford, Home Correspondent, Richard Hobson, Nicholas Russell, Martin Mears, Christopher Walker, Chief Ireland Correspondent, Michael Evans and Martin Fletcher, Michael Evans Defence Editor, David Pannick, Donald Foreman, Caroline Merrell, Banking Correspondent, Chris Ayres, Media Business Correspondent, Jeremy Kingston, James Bone, Alistair Bonnington, Clive Davis, Ian Cundell, David Robinson and Perry Cleveland-Peck, Tony Patrick, Roland Watson, Chief Political Correspondent, Kevin Eason, Fraser Nelson, Retail Correspondent, Richard Wallis, Joe Joseph, Antonia Senior, Carl Evans, Pat Gibson, Ruth Gledhill, Religion Correspondent, John Spencer, Stewart Tendler Crime Correspondent, Paul Durman and Valerie Elliott, Dominic Walsh, Dr Jane Collins, Tim Reid, Dalya Alberge Arts Correspondent, Libby Purves, Matthew Parris Political Sketch, David J. Gee, Heather Nicholson, Alan Hamilton, Matt Sims, Alix Ramsay, Tennis Correspondent, David Hands, Michael Chambers, Helen Rumbelow, John O'leary, Peter Barnard, Alison Gurden, Lisa Armstrong and Deborah Brett, Bob Lister, Daniel McGrory, Paul Armstrong, Richard Cork, Marit Hargie, John Hopkins, Steuart & Francis, Celia Brayfield, David Powell Athletics Correspondent, Ian Michaels, Raymond Keene, Adam Sage, Christine Buckley, Matt Dickinson, Paul Wilkinson, Nigel Savage, Grace Bradberry and Dalya Alberge, John Maples, J. K. Murphy, Carl Mortished, International Business Editor, Richard Owen, Ashley B. Grossman, Damian Whitworth, Roger Boyes, Nigel Hawkes, Science Editor, Grania Langdon-Down, Philip Webster, Political Editor, Glen Owen, Nick Szczepanik, John Cooper, Tom Winnifrith, James Doran, Giles Whittell, Philip Webster Political Editor, James Buckley, Simon De Bruxelles, M. V. Dover, Michael Dynes and Jan Raath, Philip Roe, Chris McGrath, Russell Jenkins, Martin Fletcher and Nigel Glass, Walter Gammie, Peter Riddell, Ben MacIntyre, John Malpas, John Hill, Martin Newcastle, Lea Paterson, Tim Jones, Michael Fabricant, Chris Ayres, Perry Cleveland-Peck, Fran Littlewood, Barry Wigmore, Benedict Nightingale, Mike Nicholas, Richard Morrison, James Doran, City Correspondent, Frances Gibb, Arthur Leathley, Adam Sherwin, Allan Hall, Roland Watson Chief Political Correspondent, David Hands, Rugby Correspondent, Janine di Giovanni, Christopher Irvine, Alan M. Barker,
... Times Unit Trust Information Service Rathbone Unit Trust Mgmt Ltd Scottish Widows Fund Mgmt Sell Buy +/- Yld % Picture Gallery He's found ...
2000 - Gale Group | TDA
Pei-Fang Wu, Kuan‐Ting Kuo, Lu‐Ting Kuo, Yi‐Ting Lin, Wei-Chung Lee, Yen‐Shen Lu, James Chih‐Hsin Yang, Ruey‐Meei Wu, Yong‐Kwang Tu, Jui-Chang Tasi, Ham-Min Tseng, Sheng-Hong Tseng, Ann‐Lii Cheng, Ching‐Hung Lin,
O(6)-Methylguanine-DNA methyltransferase (MGMT) is critical for repairing pro-mutagenic DNA bases and is correlated with response to alkylating agents in cancers. Since there is ... of brain metastases, this study aimed to evaluate MGMT expression as well as its prognostic value in ... We studied the expression and methylation status of MGMT in 86 brain metastases of lung cancers. Twenty ... primary lung tumor tissues available for direct comparison. MGMT expression was assessed by immunohistochemistry (IHC); the methylation ...
Tópico(s): Glioma Diagnosis and Treatment
2009 - Elsevier BV | Lung Cancer
Giles Tremlett, Maurice Salzedo, Raymond Snoddy Media Editor, Helen Johnstone, Robert Cole, Sally Brock, Carole Klein, James Moore, John Bierman and Colin Smith, Frances Gibb Legal Editor, Tom Griffiths, Magnus Linklater, J. A. Dukes, John Lefley, Richard Hobson, Martin Bell, Robert Lea, Dee O'connell, Philip Howard, Adam Mars-Jones, Joanna Bale, Elizabeth Judge, Melissa Kite and Tom Baldwin, Barbara Ellen, Geoff Brown, Joe Joseph, Bernard Capp, John Woodcock Cricket Commentary, Arnold Freedman, Cranborne, Valerie Elliott Countryside Editor, John Bryant, Stewart Tendler Crime Correspondent, David Charter Education Correspondent, Williams Shawcross, Dominic Walsh, Jim McCue, Alix Ramsay Tennis Correspondent, Michael Portillo, Tim Reid, Ruth Gledhill Religion Correspondent, Michael Mulvihill, Peter Ackroyd, Kate Figes, Alan Hamilton, Oliver Wright, Mike Rosewell Rowing Correspondent, Frank Kermode, Eileen Fursland, Robert Bruce, Anselm Kuhn, Nick Szczepanik Second division, Roland Watson, Max Hastings, John Kavanagh, Helen Rumbelow, Ian McIntyre, Peter Barnard, Anthea Lawson, David Charter, Emily Davies and Richard Duce, Paul Armstrong, Sarah Johnson, Lea Paterson and Philip Webster, David Lister, Ian Scales, Anthony Storr, Peter Riddell On Politics, Peter Shorrock, Matt Dickinson Football Correspondent, Jill Sherman Whitehall Editor, Christopher Martin-Jenkins, Michael Evans, Matthew Bayley and Stewart Tendler, Celia Brayfield, Chris Patten, Adam Jones, David Powell Athletics Correspondent, Anne Barrowclough, Raymond Keene, Adam Sage, David Robinson, Clive Mathieson, Matthew Pryor, Christine Buckley Industrial Editor, Nigel Cliff, Beryl Dixon, Angela M. LeROY, Melissa Kite, Chris Ayres Media Business Correspondent, Oliver Holt, Damian Whitworth, Robert Bruce Audit, Oliver August, Alan Hamilton and Adrian Lee, Michael Dynes and Jon Ashworth, Pugh and way, Colin Baillieu, Maurice Parry-Wingfield, Martin Fletcher European Correspondent, John woodcock Cricket Commentary, Paul Corry, Giles Whittell, Tim Hames, Alex O'Connell, Mel Webb, Des Dearlove, Srikumar Sen Boxing Correspondent, Alexandra Frean Scoail Affairs Correspondent, Graham Searjeant Financial Editor, Roderick Gradidge, George Caulkin, Alan Lee, David Stafford, Iain Finlayson, Anthony Loyd, John Struthers, Ian Brodie, Ross Dunn and Richard Beeston Diplomatic Editor, Michael Dynes, Alsdair, Godfrey Golzen, Tim Jones, Geoff Armstrong, Martin Waller, Piers Brendon, Chris Ayres, Fran Littlewood, Stephen Vince, Carl Mortished International Business Editor, Benedict Nightingale, Alyson Rudd, Susan MacDonald, Tom Baldwin Deputy Political Editor, Alan Lee Racing Correspondent, Roland Watson Chief Political Correspondent, Helen Rumbelow and Ian Brodie, Thomas Stuttaford, Julia Gregson, Jan Raath, Jonathan Aitken, Hilary Brown, Christopher Irvine, Joanna Coles,
... Title CIS Unit Managers Ltd Fleming Private Fund MGMT Ltd Japan Trust In all matters of investment ... Mutual Unit Mgrs Ltd Royal & Sun Alliance Ut Mgmt Ltd Singer & Friedlander Investment Funds Ltd Boxing Lewis ...
2000 - Gale Group | TDA
Van Thang Cao, Tae‐Young Jung, Shin Jung, Shu‐Guang Jin, Kyung‐Sub Moon, In‐Young Kim, Sam-Suk Kang, Chang-Soo Park, Kyung‐Hwa Lee, Hong-Jae Chae,
... to evaluate the correlation and prognostic significance of MGMT promoter methylation and protein expression in patients with ... and June 2008. To investigate the correlation between MGMT methylation and MGMT expression, methylation-specific polymerase chain reaction (MSP) and ... staining was performed. To analyze the correlation between MGMT methylation and MGMT expression according to location, biopsies were obtained from ... Scale status, extent of removal, chemotherapeutic methods, and MGMT promoter methylation and protein expression were analyzed as ...
Tópico(s): MicroRNA in disease regulation
2009 - Lippincott Williams & Wilkins | Neurosurgery
Russell Jenkins and Philip Webster, Phil Yates, Mike Theodoulou, Jon Ashworth, Cath Urquhart, Raymond Snoddy Media Editor, Stella Shamoon, Mark Roberts, Oliver Holt Chief Sports Correspondent, Rupert Mellor, G. W. Fraser, Tom Bishop, Sally Brock, James Moore, Phyllida Gardner, Alice Lagnado and Michael Evans, Jane MacQuitty, A. B. Craven, Gary Neville, Kath Fryer, John Morgan, Pauline Longcroft, Paul Hoggart, Mark Souster, Richard Trussler, Richard Hobson, Robert Lea, Michael Evans Defence Editor, Douglas Friedli, Anthea Lawson and Robin Young, Graham Serjeant Financial Editor, Philip Howard, Ron and Patricia Thomas, James Bone, David Stokes, Clive Davis, Alexandra Frean Social Affairs Correspondent, Frank Rogers (Chairman), Carl Mortished, Sharon Linnard, Mickey Burke, paul young, Tony Patrick, Gerald Davies, Clare Stewart, Thunderer, Antonia Senior, Joyce Parsons, Martin Barrow Deputy Business Editor, Chandos Elletson, D. R., Steve Keenan, Jason Allardyce, Stewart Tendler Crime Correspondent, Melanie Tringham, Ivor Davies, Steve Bird, Dominic Walsh, Jerome Boyd Maunsell, A. Fairlie-Clarke, Alix Ramsay Tennis Correspondent, Grainne Gilmore, Michael Harvey, Ross Dunn, Nick Griffiths, Richard Robinson, Ruth Gledhill Religion Correspondent, Martin Barrow, Candida Crewe, Jo Morris, Stephen Farrell, Oliver Wright, Mark Inglefield, Mike Rosewell Rowing Correspondent, David Nicholas (Chief Executive), David Harker, Peter Millar, Rodney Milnes, simon kinnersley, George Lees, Andrew Cunningham, T. P., James Landale Political Correspondent, Doug Sager, Frances Bissell, David Irving, Caroline Cranbrook, P. B., smart idea to get the look, Antonio Carluccio, Giles Whittell and Alice Lagnado, John O'leary, Peter Barnard, David Charter, Martina Evans, Derwent May, Jackson, Alan Price-Tatbot, Malcolm Smith, Jasper Gerard, John Gay, Paula Hawkins, Maria Harding, Mary Gold, Nigel Williamson, Paul Armstrong, June Osborne, Amber Cowan, David H. Philpott, Stepehn Dalton, George Brock, L. G., Ian Adcock, Rob Wright, Graham Searjeant Personal investor, C. J. Heath, Christina Koning, Meredith Etherington-Smith, Adam Jones, Dean Belcher, Nick Barlay, William Sholto, Raymond Keene, Adam Sage, Christine Buckley, David Robinson, Clive Mathieson, Matthew Pryor, John Goodbody and Jill Sherman, Matt Dickinson, John Russell Taylor, Kate muir, Dominc Walsh, George Szirtes, Lucy Pinney, Paul Wilkinson, Christine Buckley Industrial Editor, James Allcock, Jeannette Hyde, David Davidson, Min Cooper, Clive Petty, Chris Ayres Media Business Correspondent, Cathy Harris, Rob Chapman, Richard Owen, Julie Myerson, Damian Whitworth, Christopher Martin-Jenkins Chief Cricket Correspondent, David Kettle, Sudi Pigott, Roger Boyes, Emily Davies, Adam McIntosh, Nick Hasell, Gillian Harris Scotland correspondent, Chloë Bryan-Brown, Stefan Szymanski and Tim Kuypers, John diamond, Valerie Sleith, Tony Rocca, Richard Duce, Suzanne Glass, Nick Szczepanik, BN, Bryan Easey, Giles Whittell, Jane Shilling, Roger Morsley Smith, Alex O'Connell, Mel Webb, Peter Mottley, Richard Duce and Stewart Tendler, Geoffrey Dence, Michael Dynes and Jan Raath, Kevin McCarra, Deborah King, Imran Khan, Tim Wapshott, Alan Lee, Jane Owen, Daphne Stelton, Helen Pridham, Ian Brodie, Richard Beeston Diplomatic Editor, Emma Raffan, Richard Miles, John Naish, Jason Cowley, Annabelle Thorpe, Tim Jones, JRT, Martin Waller, Charles Hennessy, Chris Ayres, Nigel Hawkes Science Editor, Carl Mortished International Business Editor, David Carlisle, Danny Baker, Fran Littlewood, Benedict Nightingale, Jill Crawshaw, Richard Morrison, Alyson Rudd, Bill Edgar, Tom Chesshyre, Paul Connolly, Elizabeth Buchan, Adam Sherwin, Neill Attewell, Alan Lee Racing Correspondent, Susie Steiner, Sally Patten, Cath Urquhart Travel Editor, Penny Perrick, Angie Spray, Julia Gregson, Fraser Nelson Retail Correspondent, Walter Ellis, Gill Hornby, Christopher Irvine, Russell, Susan Emmett,
... Joint Investors Ltd Wkly Yld Murray Johnstone Ut Mgmt Royal & Sun Alliance Ut Mgmt Ltd Singer & Friedlander Investment Funds Ltd no title ...
2000 - Gale Group | TDA
Nicholas J. Hawkins, James H-F Lee, Justin Wong, Chau‐To Kwok, Robyn L. Ward, Megan P. Hitchins,
O6-methylguanine DNA methyltransferase (MGMT) is a DNA repair protein that restores mutagenic O6-methylguanine to guanine. MGMT methylation is frequently observed in sporadic colorectal cancer ... within the transcriptional enhancer element of the promoter. MGMT methylation has also been associated with KRAS mutations, ... define the molecular and clinicopathological profiles associated with MGMT methylation. Furthermore, we assessed factors contributing to MGMT methylation in the development of colorectal cancer by ...
Tópico(s): Cancer-related molecular mechanisms research
2009 - Elsevier BV | Modern Pathology
Marion McGilvary, Phil Yates, Raymond Snoddy Media Editor, Martin Fletcher and Gillian Harris, Robert S. Serman, Robert Cole, Andrew Pierce, Sally Brock, James Moore, Grace Bradberry, Frances Gibb Legal Editor, Raymond Snoddy and Clive Mathieson, Richard Hobson, Ivo Tennant, Michael Evans Defence Editor, Philip Howard, Carol Midgley, David Prockter, Jeremy Kingston, Elizabeth Judge, Ian Cundell, Richard Eaton, Barbara Ellen, Michael Crick, Christine Buckley Industrial Correspondent, Raymond Snoddy, Joe Joseph, Pat Gibson, Valerie Elliott Countryside Editor, David Charter Education Correspondent, Steve Hare, Dominic Walsh, Ruth Gledhill, Stafford Dean, Alix Ramsay Tennis Correspondent, Michael Harvey, Ross Dunn, Victoria Maln and Richard Beeston, Sophia R. Maddison, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Michael Mulvihill, Alan Hamilton, Oliver Wright, Robin Young, Mark Inglefield, Helen Rumbelow Medical Reporter, Miranda Ingram, Valerie Elliott Consumer Editor, Charles Bremner, Michael Leapman, Charles Wilson, Peter Barnard, Anthea Lawson, David Charter, Michael Gardner, Patience Wheatcroft Business Editor, Michael Heseltine, James Doran City Correspondent, Robert Cole City Correspondent, Nigel Williamson, Daniel McGrory, Paul Armstrong, Michael J. Hendrie Astronomy Correspondent, Windlesham, David Lister, Michael Theodoulou, Tom Baldwin, Matt Dickinson Football Correspondent, Jill Sherman Whitehall Editor, Christopher Martin-Jenkins, Richard Beeston Diplomatic Editor and Jan Raath, Barry Millington, John Hopkins Golf Correspondent, Geoffrey Dean, Stephen Wood, Edward Young, Adam Jones, Ian Michaels, Marcus Binney, Peter Davalle, David Robinson, Clive Mathieson, Christine Buckley Industrial Editor, Stefano Hatfield, peter Barnard, Mary Ann, Nigel Hawkes, Christopher Walker Chief Ireland Correspondent, Chris Ayres Media Business Correspondent, Damian Whitworth, Christopher Martin-Jenkins Chief Cricket Correspondent, Nick Hasell, David J. P. Vale, Hettie Judah, David Hands Rugby Correspondent, Simon Edwards, Jennifer O'Neill, Adam Fresco, John Goodbody, Dominic Kennedy, James Doran, Giles Whittell, Philip Webster Political Editor, Martin Ewans, Jane Shilling, Brian MacArthur, Mel Webb, Srikumar Sen Boxing Correspondent, Paul McCann Media Correspondent, Tom Baldwin, Raymond Snoddy and Lea Paterson, Chris McGrath, Peter Golden, Russell Jenkins, Peter Riddell, Ben MacIntyre, Clive Mathieson and Chris Ayres, Rupert White, Liam Colley, Richard Beeston Diplomatic Editor, Ben MacIntyre and James Bone, Simon Jenkins, Fraser Nelson, David Sinclair, Martin Waller, Mark Henderson, Nigel Hawkes Science Editor, Paul McCann and Chris Ayres, Dr Thomas Stuttaford, John Parfitt, Sam Kiley, Adam Sherwin, Donald Trelford, Tom Baldwin Deputy Political Editor, Ian Lloyd, Allan Hall, Lea Paterson Economics Correspondent, Tom Baldwin and Andrew Pierce, Sally Patten, Joe Van Den Bergh, Jan Raath, Fraser Nelson Retail Correspondent, Rosemary Simon, Patience Wheatcroft, Christopher Irvine, Arthur Leathley Transport Correspondent,
... Unit Managers Ltd No Title Fleming Private Fund MGMT Ltd No Title Nfu Mutual UNIT MGRS Ltd Royal & Sun Alliance UT MGMT Ltd Singer & Friedlander Investment Funds Ltd No Title ...
2000 - Gale Group | TDA
Barbara Ingold, Peter Schraml, Frank L. Heppner, Holger Moch,
The O6-methylguanine-methyltransferase (MGMT) promoter methylation status is a predictive parameter for the response of malignant gliomas to alkylating agents such as temozolomide. First ... This may be due to the fact that MGMT promoter methylation of brain metastases has not yet been explored in depth. Therefore, we assessed MGMT promoter methylation of various brain metastases including those ... methylation-specific polymerase chain reaction (MS-PCR) and MGMT immunoreactivity. Fifty-nine of 199 brain metastases (29. ...
Tópico(s): Epigenetics and DNA Methylation
2009 - Public Library of Science | PLoS ONE
Anna Karenina, Roy Haycock, Roger Singleton, Raymond Snoddy Media Editor, Helen Johnstone, Nick Nuttall Environment Correspondent, Catherine Philip, Robert Cole, Mike Spence, Sally Brock, James Moore, Howard Pollack, Magnus Linklater, Alexandra Frean Local Government Correspondent, Valerie Elliott and Nick Nuttall, David Lister and Charles Bremner, Richard Hobson, David Lister and Lea Paterson, Ivo Tennant, Robert Lea, Robert Harvey, Michael Evans Defence Editor, Philip Howard, Adam Mars-Jones, Norman Blackwell, Gillian Harris and Martin Fletcher, Jeremy Kingston, James Bone, John Kenny, Lynne Truss, Carl Mortished, Michael Ondaatje, Geoff Brown, Joe Joseph, Andrew Norfolk, Giles Coren, John O'Leary Education Editor, John Thicknesse, Martin Fletcher, Mark Griffiths, Conal Urquhart, Valerie Elliott Countryside Editor, Robert Tallon, Paul Fitzpatrick, Pat Gibson, David McVay, Valerie Elliott, Alice Fowler, Thrasy Petropoulos, Stewart Tendler Crime Correspondent, David Charter Education Correspondent, Joss Bundy, Shirley English, P. M. Mitchell, Michael Harvey, Ross Dunn, Dalya Alberge Arts Correspondent, Paul Peachey and Alex O'Connell, Anita Chaudhuri, Richard Ford Home Correspondent, Stephen Farrell, Simon Tebbutt, Alan Millard, Jenny MacArthur, Robert Bruce, Helen Dunmore, Eve-Ann Prentice, Paul Armstrong and Sally Patten, John O'Leary, Anatole Kaletsky, Adam Sage, Adrian Lee and Charles Bremner, Philip Slater Chairman, David Charter, Stuart Crainer, Caroline Merrell Banking Correspondent, James Doran City Correspondent, J. E. Mitchell, Paul Armstrong, Paul Nicolson, Chairman, Michael Theodoulou, Atle Naess, William Dartmouth, Christopher Martin-Jenkins, Barry Millington, Simon de Bruxelles, Geoffrey Dean, Celia Brayfield, Stephen Wood, David Watts, Raymond Keene, Peter Davalle, David Robinson, Clive Mathieson, Philip Whiteley, Mark Seddon, Christine Buckley Industrial Editor, Nigel Cliff, Nigel Hawkes, Kirstie Pelling, Christopher Walker Chief Ireland Correspondent, Melissa Kite, Richard Owen, John Carr, Roger Boyes, Oliver August, Carol Allen, David Hands Rugby Correspondent, J. C. Patrick, Peter Johnson, Nick Szczepanik, Agence France-Presse, Giles Whittell, Philip Webster Political Editor, James Doran, Anne Born, James Pringle, Alex O'Connell, Annie Turner, Graham Searjeant Financial Editor, Antonio Tabucchi, Chris McGrath, Russell Jenkins, Michael Austin, Elizabeth Walston, Catherine O'Brien, Peter Riddell, John Goodbody Sports News Correspondent, David Williams, Nick Hassell, Michael Dynes, Martin Waller, Gillian Harris, Nigel Hawkes Science Editor, Simon Ingram, Carl Mortished International Business Editor, Mark Baldwin, Fran Littlewood, Continued overleaf, Michael Prior, Dr Thomas Stuttaford, Ed. James Grauerholz, Jack Bailey, Bill Edgar, Richard Morrison, Tariq Ali, Valerie Grove, Adam Sherwin, Susan MacDonald, Tom Baldwin Deputy Political Editor, Andy Bowles, Edmund Dell, Bruce Shaxson, Robert Whymant, Alan Lee Racing Correspondent, Lea Paterson Economics Correspondent, Roland Watson Chief Political Correspondent, Jane Chambers, Nunzio Quacquarelli, Patience Wheatcroft, Christopher Irvine, Russell, Philippa Butler, Susan Emmett,
... Unit Managers Ltd No Title Murray Johnstone Ut Mgmt No Title Royal & Sun Alliance Ut Mgmt Ltd No Title Singer & Friedlander Investment Funds Ltd ...
2000 - Gale Group | TDA
Silvia Uccella, Roberta Cerutti, Claudia Placidi, Silvia Marchet, Ileana Carnevali, Barbara Bernasconi, Ilaria Proserpio, G. Pinotti, Maria Grazia Tibiletti, Daniela Furlan, C. Capella,
... the detection of O 6 -methylguanine-DNA methyltransferase (MGMT) gene methylation status (MS) in diffuse large B- ... To determine the immunohistochemical (IHC) expression of the MGMT protein and correlate it with MS. Both IHC ... 71 patients with primary nodal DLBCL were studied. MGMT immunoreactivity was detected using a specific monoclonal antibody. The MS of MGMT gene was analysed in 52/71 DLBCL using ... MS results. Results: 19/71 DLBCLs (27%) were MGMT-negative at IHC; all were analysed, together with 33/52 MGMT-positive DLBCLs. MethyLight showed a better performance than ...
Tópico(s): Cancer Genomics and Diagnostics
2009 - BMJ | Journal of Clinical Pathology
Sarah Potter Women's cricket, Jon Ashworth, Raymond Snoddy Media Editor, Helen Johnstone, Robert Cole, Andrew Pierce, Hilary Sage, Sally Brock, Frances Gibb Legal Editor, Kevin Cullen, Ian Blackshaw, Robert Lefever, Robert Lea, Philip Howard, David Pannick, Michael Binyon, John Curtis, James Bone, David Tipping, Alexandra Frean Social Affairs Correspondent, Elizabeth Judge, Roger Maynard, Jeremy Whittle, Kevin Eason, Geoff Brown, Raymond Snoddy, Joe Joseph, Andrew Norfolk, Carl Evans, Conal Urquhart, Pat Gibson, Chris G. Green, Valerie Elliott, P. Quinton, David Charter Education Correspondent, Dominic Walsh, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Martin Barrow, Libby Purves, Kit Nicholson, John Ennis, Michael Mulvihill, Richard Ford Home Correspondent, Nicholas Blanford, Robin Young, Stephen Farrell, Rodney Milnes, Phil Thomas and Alison Rees, Terry Hart-Jones, Anatole Kaletsky, Helen Rumbelow Medical Reporter, Valerie Elliott Consumer Editor, Mike Bradley, Charles Bremner, Tom Flanagan, Michael Chambers, Helen Rumbelow, Peter Barnard, Anthea Lawson, Robert Cole City Correspondent, Sally Jones, Daniel McGrory, Paul Armstrong, Edward Fennell, Paul Nicolson, Chairman, Mark Findlay, Audrey Ferrle, Audrey Ferrie, Cyril Fox, Matt Dickinson Football Correspondent, Mark Griffiths Horticultural Correspondent, Martin Fletcher, Tom Baldwin and Lea Paterson, Susan Clark, Christopher Martin-Jenkins, John Hopkins Golf Correspondent, Rob Wright, Geoffrey Dean, Stephen Wood, Adam Jones, Marcus Binney, Stuart Nicholson, Raymond Keene, David Robinson, Clive Mathieson, Christopher Walker Chief Ireland Correspondent, Melissa Kite, Chris Ayres Media Business Correspondent, Cathy Harris, Christopher Martin-Jenkins Chief Cricket Correspondent, Clare Sterling, John FitzGERALD, Roger Boyes, R. W. A. Letham, Oliver August, Nick Hasell, David Hands Rugby Correspondent, Julian Muscat, Glen Owen, John Allison, Nick Szczepanik, John Goodbody, Dominic Kennedy, John O'Leary Education Editor and Damian Whitworth, Susie Steiner Property Correspondent, Joanna Pitman, Giles Whittell, Philip Webster Political Editor, Andrew Plerce, James Tooth, Alex O'Connell, Mel Webb, Jane Collins, Jack Straw, George Caulkin, Anthony Loyd, Peter Riddell, Ben MacIntyre, Patience Wbeatcroft, Daniela Nardini, Michael Gove, Richard Beeston, Steven Berkoff, Fraser Nelson, Tim Jones, Martin Waller, Benedict Nightingale, Grania …, Robin Young and Paul McCann, Sam Kiley, Alice Miles, Vince Wright, Michael Evans, Giles Coren Parliamentary Sketch, Alan Lee Racing Correspondent, Lea Paterson Economics Correspondent, Roland Watson Chief Political Correspondent, Sally Patten, Edward Gorman Sailing Correspondent, Fraser Nelson Retail Correspondent, Rosemary Nelson, Patience Wheatcroft, Christopher Irvine,
... Ltd No Title Henderson Investors Murray Johnstone UT Mgmt Hargreaves Landsdown Overseas Growth Funds Royal & Sun Alliance UT MGMT Ltd Singer & Friedlander Investment Funds Ltd No Title ...
2000 - Gale Group | TDA
Sibille Everhard, Jörg Tost, Hafida El abdalaoui, Emmanuelle Crinière, Florence Busato, Yannick Marie, Marta Gut, Marc Sanson, Karima Mokhtari, Florence Laigle–Donadey, Khê Hoang‐Xuan, Jean‐Yves Delattre, Joëlle Thillet,
The O(6)-methylguanine-DNA methyltransferase gene (MGMT) is methylated in several cancers, including gliomas. However, the functional role of cysteine-phosphate-guanine (CpG) island (CGI) methylation in MGMT silencing is still controversial. The aim of this study was to investigate whether MGMT CGI methylation correlates inversely with RNA expression of MGMT in glioblastomas and to determine the CpG region ... quantitative method, and analyzed with respect to their MGMT mRNA expression status. Three groups of patients were ...
Tópico(s): Cancer Genomics and Diagnostics
2009 - Oxford University Press | Neuro-Oncology
James Landale, Anjana Ahuja Science Briefing, Miles Fothergill, Sally Brock, James Moore, Bernard Garston, Patricia Davies, Grace Bradberry, Frances Gibb Legal Editor, Jennifer Bone (Chair), Martin Richards, Richard Hobson, Ivo Tennant, Robert Lea, David Blunkett, Philip Howard, Adam Mars-Jones, Barry Goodchild, Michael Binyon, Alexandra Frean Social Affairs Correspondent, Carl Mortished, Graham Stewart, Jeremy Whittle, Peter Quarrell, Joe Joseph, John O'Leary Education Editor, Mike Clark, Conal Urquhart, Paul Fitzpatrick, David McVay, John Bryant, Thrasy Petropoulos, Melanie Tringham, Lewis Lyons, Steve Bird, Debra Craine, Alasdair Reid, Jeremy Clarkson, Hugh Leggatt, Alix Ramsay Tennis Correspondent, Vicky Tuck, Principal, Ruth Gledhill Religion Correspondent, Richard Ford Home Correspondent, Godfrey Barker, Alan Hamilton, Helen Rumbelow and Tom Baldwin, Oliver Wright, Mark Inglefield, James Landale and Tom Baldwin, Mike Rosewell Rowing Correspondent, Sydney E. Wilkins, Robert Bruce, William Burns, Peter O. Miles, Charles Bremner, Peter Barnard, Stuart Crainer, James Doran City Correspondent, Russell Kempson, Robert Cole City Correspondent, Ted Awty, David Lister, Matt Dickinson Football Correspondent, Jill Sherman Whitehall Editor, Jenny Booth, Christopher Martin-Jenkins, Nigel Willamson, Geoffrey Dean, Tom Baldwin and James Landale, Adam Jones, Raymond Keene, David Robinson, Clive Mathieson, Sean MacAulay, Philip Whiteley, Helen Rumbelow and Roland Watson, Paul Wilkinson, Christine Buckley Industrial Editor, Nigel Cliff, Beryl Dixon, Caroline Merrell, Christopher Walker Chief Ireland Correspondent, Oliver Holt, Richard Owen, Damian Whitworth, Sally Morris, Roger Carpenter, Director, Michael R. Dolbear, Andrew Emmerson, R. W. Johnson, Martin Fletcher European Correspondent, Ruth Hilton, Alan Cottrell, Giles Whittell, David Adams and Christopher Walker, Alex O'Connell, Mel Webb, Annie Turner, Graham Searjeant Financial Editor, Anjana Ahuja, Chris McGrath, George Caulkin, Russell Jenkins, Moira Petty, Michael Austin, Ben MacIntyre, Michael Dynes, Chris Quick, Fraser Nelson, Martin Waller, Anthony Foster, Kenneth MacNab, Nigel Hawkes Science Editor, Carl Mortished International Business Editor, Jeffrey Joy, Mark Baldwin, Benedict Nightingale, Dr Thomas Stuttaford, Jack Bailey, Alyson Rudd, Richard Morrison, James Christopher, Pamela Wright, Valerie Grove, Adam Sherwin, Susan MacDonald, Simon Crompton, Michael Evans, Andrew Finkel, Hugh Sebag-Montefiore, Robert Rhodes, Lea Paterson Economics Correspondent, Roland Watson Chief Political Correspondent, Fraser Nelson Retail Correspondent, Russell,
... Title Cis Unit Managers Ltd Fleming Private Fund Mgmt Ltd No Title Japan Trust Over 50 with ... Far Eastern Gib Equity Royal Sun Alliance Ut Mgmt Ltd Singer & Friedlander Investment Funds Ltd Sport Hollow ...
2000 - Gale Group | TDA
Martin J. van den Bent, Hendrikus J. Dubbink, Marc Sanson, Cathleen R. van der Lee-Haarloo, Monika E. Hegi, Judith W. M. Jeuken, Ahmed Ibdaih, Alba A. Brandes, Martin Taphoorn, Marc Frénay, Denis Lacombe, Thierry Gorlia, Winand N.M. Dinjens, Johan M. Kros,
Purpose O6-methylguanine-methyltransferase (MGMT) promoter methylation has been shown to predict survival of patients with glioblastomas if temozolomide is added to radiotherapy (RT). It is unknown if MGMT promoter methylation is also predictive to outcome to ... fixed, paraffin-embedded tumor tissue was available for MGMT promoter methylation analysis. This was investigated with methylation ... dependent probe amplification. Results In 152 cases, an MGMT result was obtained, in 121 (80%) cases MGMT promoter methylation was observed. Methylation strongly correlated with ...
Tópico(s): Brain Metastases and Treatment
2009 - Lippincott Williams & Wilkins | Journal of Clinical Oncology