Srikumar Sen, Boxing Correspondent, Andrew Histop, Frances Gibb, Legal Affairs Correspondent, David Thornton, Andrew Billen, Nick Nuttall, P. G., Thomson Prentice and Howard Foster, Michael Hendrie Astronomy Correspondent, Ann Holmes, Stephen Leather, N. Hooper, Cliff Feltham, Harvey Elliott, Ruth Gledhill and Philip Jacobson, Ivo Tennant, Joan Llewelyn Owens, Philip Howard, John Bell, City Editor, Nuala Scarisbrick, Michael Binyon, Clifford Longley Religious Affairs Editor, Dudley Fishburn, Carol Leonard, Richard Streeton, Allan Winn Editor, Commercial Motor, Colin Narbrough, John Spicer, Employment Affairs Correspondent, Christopher Morris, John Maddox, Joe Joseph, Judith R. Oddy, Jim Railton, Roger Lean-Vercoe, Michael Tate, Michael Bryant, Ruth Gledhill, Jill Sherman, Social Services Correspondent, Steven Brull, Michael T. H. Banks, Pearce Wright Science Editor, Louise Taylor, Lawrence Lever, Mick Cleary, Peter Waymark, Hugh Montefiore, Jenny MacArthur, John Young, Marcus Williams, Michael Hamlyn, Caroline Berman, John Percival, Andrew English Commercial Motor, Rex Bellamy, Tennis Correspondent, Martin Fletcher Political Reporter, Malcolm Smith, Edward Fennell, John Woodcock, David Cross, Sydney Friskin, Nicholas Harling, David Smith, Economics Correspondent, David Miller, Robert Matthews Technology Correspondent, Geoffrey Wheeler, (Michael Phillips), Nicolas Soames, D. K. Henderson, John Higgins, Christopher Goulding, Peter Davalle, Nicholas Beeston, Barbara Amiel, John Russell Taylor, Peter Dear and Jane Rackham, Barryfantoni, Craig Brown, Yuri Matischen, Paul Griffiths, Alexandra Jackson, Roland Rudd, Phil McLennan, Richard Evans, F. F. Dajani, Craig Seton, John Blunsden, Richard Owen, Jonathan Shepherd, John Bell, Geof Jarvis, Keith Hartley, Sheila Gunn Political Staff, G. S. P. Freeman-Grenville, Geof Wheelwright, Gordon Peters, John Goodbody, Stewart Rayment, Carol Ferguson, Kevin E. Thomas, Daniel Ward Motor Industry Correspondent, Malcolm McKeag, Paul Newman, Liz Smith, Sarah Jane Checkland Art Market Correspondent, Michael Hornsby, Michael Clark and Geoffrey Foster, Lord Hailsham, Tony Dawe, Illtyd Harrington, Andrew Morgan and Andrew Moger, Tim Jones, Peter Mulligan, Martin Waller, Michael Horsnell, Robert Matthews and Pearce Wright, Noël Goodwin, Robert Fisk, David Tytler, Education Editor, Michael Evans Defence Correspondent, William Goodhart Sld, Rodney Lord, Economics Editor, Jack Bailey, Clive Saffery, David Powell, Pat Butcher Athletics Correspondent, Philip Webster and Roland Rudd, Richard Ford, Political Correspondent, John Martin Sdp, Richard Sarson, David Young Energy Correspondent, Philip Jacobson, David Hands, Rugby Correspondent, Vivien Goldsmith, Family Money Editor, Mary Dejevsky, Christopher Warman and David Walker, Peter Coy,
... Financial Deputy Treasurer Multiple Display Advertising Items Solicitor MPB & CO Hamlin Slowe Solicitors Gabriel Duffy Consultancy Badenoch & ...
1988 - Gale Group | TDA
K Hasløv, Åse Bengård Andersen, Michael Weis Bentzon,
MPB 70 is a protein found in large quantities in the culture filtrate (CF) of the Tokyo ... these strains. We estimated the molecular weight of MPB 70 to 22,000 by sodium dodecyl sulphate- ... SDS-PAGE). SDS-PAGE and immunoblotting showed that MPB 70 was present in high quantities in CF ... CF from M. tuberculosis H37Rv. When the purified MPB 70 preparation used in the present study was ... a polyclonal rabbit or a monoclonal mouse anti-MPB 70 antibody, several bands in addition to the ... band were seen, indicating a tendency of the MPB 70 molecules and/or fragments thereof to form ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
1987 - Wiley | Scandinavian Journal of Immunology
National Bureau of Economic Research (NBER)
Lana S. Weckbach, J L Staneck,
... was compared with a conventional vented monophasic bottle (MPB-A) for use in the routine culture of ... for the BiPB slant. A third unvented bottle (MPB-N) with Columbia broth was included as part ... an exclusively positive anaerobic bottle. Both BiPB and MPB-A were positive in 235 of the remaining ... were recovered in both the BiPB and the MPB-A from the same set; 105 isolates grew in the BIPB but not in MPB-A, 95 isolates grew only in the MPB-A but not in BiPB, and 69 grew exclusively in the MPB-N. The BiPB allowed more rapid recovery of ...
Tópico(s): Mycobacterium research and diagnosis
1986 - American Society for Microbiology | Journal of Clinical Microbiology
National Bureau of Economic Research (NBER)
... stereoselectivity of the metabolism and pharmacokinetics of methylphenobarbital (MPB) was studied in six healthy adult male volunteers ... the drug. The R- and S-enantiomers of MPB were analyzed in plasma by an enantioselective HPLC method, and the enantiomers of the 4-hydroxy-MPB metabolite in urine by a similar procedure. The (R)-MPB was extensively hydroxylated, with an average of 49. ... being recovered in urine as (R)-4-hydroxy-MPB. Only 7.16% of the (S)-MPB was converted to the corresponding hydroxy metabolite. The ...
Tópico(s): Epilepsy research and treatment
1989 - American Society for Pharmacology and Experimental Therapeutics | Drug Metabolism and Disposition
Khalid Sharif, Patrick McKiernan, Jean de Ville de Goyet,
... threatening bleeding, thrombocytopenia, and coagulation disorders. Mesoportal bypass (MPB) restores normal physiologic portal flow to the liver ... is, however, little long-term outcome data after MPB. The aim of our study was to analyze the long-term outcome after MPB in children.Retrospective single-center review of all MPB with more than 5-year follow-up was ... children between 1998 and 2003.Thirty children underwent MPB, which was successful in 29. Long-term follow- ... large colic vein (n = 2). Median time since MPB is 8 years (range, 5.3-8.8 ...
Tópico(s): Abdominal vascular conditions and treatments
2009 - Elsevier BV | Journal of Pediatric Surgery
M. Brown, T. Andrew Black, Zoran Nesic, Vanessa N. Foord, David L. Spittlehouse, Art Fredeen, N.J. Grant, Philip J. Burton, J. A. Trofymow,
... Canada is experiencing a severe mountain pine beetle (MPB) (Dendroctonus ponderosae) epidemic extending over an area of ... dominated stands in the central interior of BC. MPB-06 is an 83-year-old stand that ... 2008 only 21% of the trees remained healthy. MPB-03, a 110-year-old stand, had >95% ... a 2003 beetle attack, and also differed from MPB-06 in that it had a more developed ... measurements were also conducted in two stands near MPB-06 harvested in 2005 and 1997 (CC-05 ... week periods each during the 2007 growing season. MPB-06 had an annual NEP of −82 and − ...
Tópico(s): Forest ecology and management
2009 - Elsevier BV | Agricultural and Forest Meteorology
Produção Nacional
Revisado por pares
Migdalys Salazar, Lorena Moscardelli, William L. Fisher, María Antonieta Lorente,
The Morichito piggyback basin (MPB) is a SW–NE-oriented depocenter in the Eastern Venezuelan Foreland Basin (EVFB). This piggyback basin formed by overlying the ... between the Caribbean and South-American Plates. The MPB covers an area encompassing approximately 1000 km2 between ... confining barrier on the southern boundary of the MPB. Previous studies have tried to address the tectonostratigraphic significance of the MPB, but new biostratigraphic information and recently acquired 3D ... to expand the understanding of this basin. The MPB occupies a relatively small area of the EVFB; ...
Tópico(s): Geological and Geophysical Studies Worldwide
2009 - Elsevier BV | Marine and Petroleum Geology
Springer Link
... Say), often coexists with the mountain pine beetle (MPB), Dendroctonusponderosae Hopk., in lodgepole pine, Pinuscontorta var. latifolia ... The PE colonizes the upper bole, while the MPB infests the lower bole. We investigated the hypothesis that interspecific interactions between the PE and the MPB within trees can adversely affect MPB progeny production or survival. In lodgepole pine bark attacked by both species, PE and MPB emergence holes had a strong negative interrelationship, suggesting ... pine logs resulted in significantly decreased numbers of MPB progeny, particularly when MPBs and PEs were allowed ...
Tópico(s): Plant Pathogens and Fungal Diseases
1991 - NRC Research Press | Canadian Journal of Forest Research
Wiley Online Library
Mijung Kwon, Jennifer F. Caplan, Nolan R. Filipenko, Kyu‐Sil Choi, Sandra L. Fitzpatrick, Libo Zhang, David M. Waisman,
... from Caltag Laboratories, Inc. 3-(N-Maleimidopropionyl)biocytin (MPB) was purchased from Molecular Probes. Reduced glutathione, iodoacetamide, ... the reaction mixture was incubated with 100 μm MPB at room temperature for 30 min. The reaction ... temperature for 10 min to quench the unreacted MPB. The unreacted glutathione and other free thiols in ... p11, or p36 was incubated with 100 μm MPB in a buffer containing 20 mm Tris, pH ... with 5% skim milk. In the case of MPB-reacted protein samples, the membrane was blocked and ...
Tópico(s): Protease and Inhibitor Mechanisms
2002 - Elsevier BV | Journal of Biological Chemistry
... by the selective biotinylation [3- (N-maleimidylpropionyl) biocytin (MPB)] or alkylation [4-acetamido-4′-maleimidylstilbene-2,2′- ... labeling strategy relied on the relative impermeability of MPB to the inner membrane of E.coli (Wada ... membrane impermeability of AMS (Long et al., 1998). MPB presumably readily passes through the pores of the ... with membrane-impermeable AMS prior to addition of MPB. Cysteines protected from reactivity with MPB, from the outside of either whole cells or ... for the sidedness-dependent modification of cysteines by MPB were established using whole cells and IOV containing ...
Tópico(s): RNA and protein synthesis mechanisms
2002 - Springer Nature | The EMBO Journal
Project Gutenberg
Angelina J. Lay, Xing‐Mai Jiang, Elise B. Daly, Lisa Sun, Philip J. Hogg,
... protein inhibit reductase activity. 3-(N-Maleimidylpropionyl)biocytin (MPB) and dibromobimane (bBBr) were from Molecular Probes, Eugene, ... thiols generated in plasmin/angiostatin were labeled with MPB (100 μm) for 30 min at 37 °C followed by quenching of the unreacted MPB with GSH (200 μm) for 10 min at ... plasmin reduction were employed. In one assay, the MPB-labeled plasmin/angiostatin fragments were immobilized on wells ... and then washed two times with HEPES/Tween. MPB-labeled plasmin/angiostatin fragments were diluted 1:8 ...
Tópico(s): Angiogenesis and VEGF in Cancer
2002 - Elsevier BV | Journal of Biological Chemistry
Project Gutenberg
Anne-Lise Prost, Renaud Dérand, Laurent Gros, Frédéric Becq, Michel Vivaudou,
The substituted benzo[c]quinolizinium compounds MPB-07 and MPB-91 are novel activators of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. High homologies between CFTR and ... patch–clamp technique. Channels were practically unaffected by MPB-07 but were fully blocked by MPB-91 with half-inhibition achieved at ∼20 μM MPB-91. These effects were similar on channels formed ... known to interfere with its nucleotide-binding capacity. MPB-91, but not MPB-07, was able to displace binding of glibenclamide ...
Tópico(s): Cardiac Ischemia and Reperfusion
2003 - Elsevier BV | Biochemical Pharmacology
Wei Zhang, Mikhail Bogdanov, Jing Pi, A J Pittard, William Dowhan,
... AMS) and (+)-biotinyl,3-maleimidopropionamidyl-3,6-dioxaoctanediamine (MPB) were purchased from Molecular Probes, Inc. and Pierce ... or without AMS pretreatment) were biotinylated by adding MPB to a final concentration of 100 μm, followed ... described below. Immunoprecipitation and Western Blot Analysis—After MPB labeling, cells were lysed by addition of an ... cysteine residues in these loops to sulfhydryl reagents. MPB is a biotinylated sulfhydryl-specific probe that readily ... of the inner membrane should be derivatized by MPB, whereas cysteines located on cytoplasmic side of the ...
Tópico(s): Photosynthetic Processes and Mechanisms
2003 - Elsevier BV | Journal of Biological Chemistry
Project Gutenberg
Tsuyoshi Nishi, Shoko Kawasaki-Nishi, Michael Forgac,
... the membrane-permeable reagent 3-(N-maleimidylpropionyl)biocytin (MPB) and the -impermeable reagent 4-acetamido-4′-maleimidylstilbene- ... tested, two (S5C and S178C) were labeled by MPB. MPB-labeling of S5C was blocked by AMS in ... the membrane-permeable reagent 3-(N-maleimidylpropionyl)biocytin (MPB) and the -impermeable reagent 4-acetamido-4′-maleimidylstilbene- ... tested, two (S5C and S178C) were labeled by MPB. MPB-labeling of S5C was blocked by AMS in ... morpholino)ethanesulfonic acid; YEPD, yeast extract peptone dextrose; MPB, 3-(N-maleimidylpropionyl) biocytin; AMS, 4-acetamido-4′- ...
Tópico(s): Photosynthetic Processes and Mechanisms
2003 - Elsevier BV | Journal of Biological Chemistry
Caroline Norez, Frédéric Bilan, Alain Kitzis, Yvette Mettey, Frédéric Becq,
... action of several pharmacological chaperones benzo[ c ]quinolizinium (MPB), we analyzed their effects on two CF mutations; ... but, unlike F508del, could not be rescued by MPB. A structure-activity relationship for F508del functional correction revealed the following profile: MPB-104-91-07-80 > 05 > 89 ≫ 9-hydroxyphenanthrene = ... airway epithelial F508del/F508del CF15 cells showed that MPB did not prevent the interaction of F508del-CFTR ... or calnexin. Functional rescue of F508del-CFTR by MPB and miglustat was abolished by brefeldin A (BFA) ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2008 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
National Bureau of Economic Research (NBER)