Xiangchong Wang, Qingzhong Jia, Yulou Yu, Handong Wang, Huicai Guo, Xindi Ma, Chuntong Liu, Xueyan Chen, Qingfeng Miao, Bingcai Guan, Suwen Su, Heming Wei, Chuan Wang,
... investigated the cardiac effects of ACO and mesaconitine (MACO), a structurally related analog of ACO identified in ... We showed that intravenous administration of ACO or MACO (25 μg/kg) to guinea pigs caused various ... AVB), ventricular tachycardia (VT), and ventricular fibrillation (VF). MACO displayed more potent arrhythmogenic effect than ACO. We ... treatment with ACO (0.3, 3 μM) or MACO (0.1, 0.3 μM) depolarized the resting ... in a concentration-dependent manner. The ACO- and MACO-induced AP remodeling was largely abolished by an ...
Tópico(s): Poisoning and overdose treatments
2020 - Springer Nature | Acta Pharmacologica Sinica
Meng Ying-chun, Zhenying Ding, Hai‐Quan Wang, Liping Ning, Chao Wang,
... n = 20 rats): sham operation group (Sham group), MACO group, MACO+microRNA-155 mimic group, and MACO+microRNA-155 inhibitor group. Sham group was given the free graft, while MACO+microRNA-155 mimic group and MACO+microRNA-155 inhibitor group were treated with microRNA- ... symptom of neurologic impairment, while rats in the MACO group had the obvious neurologic impairment. After being ... with microRNA-155 inhibitor, the neural function of MACO rats had been improved, with the decreased area ... that, after being treated with microRNA-155 inhibitor, MACO rats had the increased expression of AT1R and ...
Tópico(s): Neurological Disease Mechanisms and Treatments
2015 - Elsevier BV | Asian Pacific Journal of Tropical Medicine
Antoine Harfouche, Farid Nakhle,
... images, videos, PDF, 3D modelsVoice, text messagesNoFreeMicrosoft Windows, macOS, AndroidHTC Vive, HTC Vive Pro, all OculusDogheadsimulations.com/ ... browser supportHubs.mozilla.comGlueImages, videos, 3D modelsVoiceYesPaidMicrosoft Windows, macOS, Android, iOSHTC Vive, HTC Vive Pro, Valve Index, ... QuestGlue.workImmersedScreen sharing, whiteboardVoiceNoFree version, paid featuresMicrosoft Windows, macOS, Ubuntu LinuxOculus Go, Oculus QuestImmersedvr.commeetingRoomWhiteboard, PDFVoiceNoFree version, paid featuresMicrosoft Windows, macOS, Android, iOSHTC Vive, HTC Vive Focus, all Oculus, ...
Tópico(s): Biomedical and Engineering Education
2020 - Elsevier BV | Trends in biotechnology
Ershad Ali Mistri, Soumen Routh, Dipa Ray, Saswata Sahoo, Manjusri Misra,
Castor oil was converted to maleated castor oil (MACO) without any catalyst. MACO was characterized with FTIR, NMR, molecular weight and ... measurement. Tung oil (20 wt%) was added to MACO as reactive diluent. Non-woven jute felts were used as reinforcing material. The MACO was polymerized and crosslinked in situ during composite fabrication. The curing behavior of MACO with free radical catalyst was investigated by differential scanning calorimetry (DSC). The MACO/jute composites were tested for their flexural properties, ...
Tópico(s): Mechanical Behavior of Composites
2011 - Elsevier BV | Industrial Crops and Products
Balasubramanian Esakki, E. Elangovan, P. Tamilarasan, G. R. Kanagachidambaresan, Dibyajyoti Chutia,
... combining well known modified ant colony optimization algorithm (MACO) and a variant of A*, namely the memory- ... an improved version of the pheromone strategy in MACO, the local trap and premature convergence are minimized, ... edges of the grids. Combining the competencies of MACO and MEA*, a hybrid algorithm is proposed to ... significant finding of this study is that, the MACO-MEA* algorithm achieved 21% less energy consumption and 55% shorter execution time than the MACO-A*. moreover, the path traversed in both simulation ...
Tópico(s): Robotics and Sensor-Based Localization
2022 - Springer Science+Business Media | Journal of Ambient Intelligence and Humanized Computing
Haoran Wang, Cheng Zhang, Ying Zhou, Qixin Zhou,
Two cardanol (CO) derivatives, methacrylated cardanol (MACO) and triethoxysilane functionalized cardanol (TSCO) were investigated as the reactive diluents for a zinc phosphate pigmented alkyd coating. It was found that 5 wt% of MACO or TSCO can reduce the dosage of xylene ... alkyd coating; however, the addition of 15 wt% MACO decreased the drying time from 12 h to ... MPa, comparing with the neat alkyd coating (without MACO and TSCO). As evidenced by the salt spray ... coating; however, the alkyd coating containing 15 wt% MACO (labelled as M-15) presented superior corrosion resistance ...
Tópico(s): Lignin and Wood Chemistry
2020 - Elsevier BV | Materials Today Communications
Jiunn‐Jye Sheu, Li‐Teh Chang, Chiang-Hua Chiang, Ali A. Youssef, Chiung‐Jen Wu, Fan-Yen Lee, Hon‐Kan Yip,
... closely related to combined major adverse clinical outcomes (MACO) [defined as advanced Killip score (≥ 3), overt congestive ... lower in patients (n = 18) with occurrence of MACO than in patients (n = 25) without occurrence of MACO (all P < 0.05). Furthermore, the level of ... LPS)-stimulated LTR-4 was significantly increased in MACO patients than in those without MACO (P < 0.0001). Moreover, LPS-stimulated TLR-4 was the most independent predictor of 30-day MACO (P < 0.01). In patients with ST-se ... TLR-4 is independently predictive of 30-day MACO.
Tópico(s): Sepsis Diagnosis and Treatment
2008 - Japanese Heart Journal Assoc | International Heart Journal
Rebecca J. Bartlett Ellis, Joan E. Haase, Todd Ruppar,
... to describe the Medication Adherence Context and Outcomes (MACO) framework, which includes contexts (ie, clinics, pharmacies, and ... persistence). The Medication and Adherence Contexts and Outcomes (MACO) framework was iteratively developed between 2015 and 2018 ... three distinct yet interrelated contexts described in the MACO framework are 1) clinical encounters, 2) pharmacy encounters, ... related outcomes (initiation, implementation, and discontinuation/persistence). The MACO framework distinguishes context-specific processes and outcomes. The ...
Tópico(s): Pharmaceutical Practices and Patient Outcomes
2023 - Dove Medical Press | Patient Preference and Adherence
Glen Stecher, Koichiro Tamura, Sudhir Kumar,
... phylogenetics and evolutionary medicine. Here, we introduce the macOS version of the MEGA software. This new version ... to use MEGA on Apple computers. MEGA for macOS utilizes memory and computing resources efficiently for conducting evolutionary analyses on macOS. It has a native Cocoa graphical user interface ... programmed to provide a consistent user experience across macOS, Windows, and Linux. MEGA for macOS is available from www.megasoftware.net free of ...
Tópico(s): Evolutionary Algorithms and Applications
2019 - Oxford University Press | Molecular Biology and Evolution
Tomohiro Kitazono, Sayuri Hara‐Kuge, Osamu Matsuda, Akitoshi Inoue, Manabi Fujiwara, Takeshi Ishihara,
... screening showed that three proteins—a membrane protein, MACO-1; a receptor tyrosine kinase, SCD-2; and ... 1/JNK-1 pathway. We further demonstrated that MACO-1 and SCD-2/HEN-1 functioned in parallel genetic pathways, and only MACO-1 regulated forgetting of olfactory adaptation to isoamyl ... revealed that this attenuation is sustained longer in maco-1 and scd-2 mutant animals than in ... regulated by three conserved proteins: a membrane protein, MACO-1; a receptor tyrosine kinase, SCD-2: and its ligand, HEN-1. MACO-1 and SCD-2/HEN-1, working in ...
Tópico(s): Circadian rhythm and melatonin
2017 - Society for Neuroscience | Journal of Neuroscience
Xamxikamar Mamat, Yong-Lei Wang, Wumanjiang Eli,
The maleic acid‐castor oil monoester (MACO) was synthesized and was used as monomer to synthesize a new potentially environmentally friendly copolymer of styrene and MACO (poly‐St/MACO) by suspension polymerization. Under the appropriate conditions, the poly‐St/MACO with yield of 81%, number average molecular weight ... could be obtained. The chemical structures of the MACO and resulting copolymer were confirmed by Mass Spectrometry ... analysis and biodegradation test showed the poly‐St/MACO can be used as a new potentially environmentally ...
Tópico(s): Polymer composites and self-healing
2011 - Wiley | Polymers for Advanced Technologies
Fausto Arellano‐Carbajal, Luis Briseño-Roa, Africa Couto, Benny H. H. Cheung, Michel Labouesse, Mario de Bono,
... organisms. Mutants for the single Caenorhabditis elegans macoilin, maco-1, exhibit a constellation of behavioral phenotypes, including defects in aggregation, O2 responses, and swimming. MACO-1 protein is expressed broadly and specifically in ... defects, nervous system development appears wild-type in maco-1 mutants. However, maco-1 animals are resistant to the cholinesterase inhibitor ... Ca2+ transients, at least in some neurons: in maco-1 mutants the O2-sensing neuron PQR is ... recapitulate the Ca2+ response defect we see in maco-1 mutants, although we do not see defects ...
Tópico(s): Photosynthetic Processes and Mechanisms
2011 - Public Library of Science | PLoS Genetics
Akiko Miyara, Akane Ohta, Yoshifumi Okochi, Yuki Tsukada, Atsushi Kuhara, Ikue Mori,
... that a novel and highly conserved protein, macoilin (MACO-1), plays an essential role in diverse neural functions in Caenorhabditis elegans. maco-1 mutants showed abnormal behaviors, including defective locomotion, ... weakly rescued the abnormal thermotactic phenotype of the maco-1 mutants, suggesting that macoilin is functionally conserved ... may have been caused by impaired locomotion of maco-1 mutants. However, calcium imaging of AFD thermosensory neurons and AIY postsynaptic interneurons of maco-1 mutants suggest that macoilin is required for ...
Tópico(s): Neurobiology and Insect Physiology Research
2011 - Public Library of Science | PLoS Genetics
Hon‐Kan Yip, Chiung‐Jen Wu, Hsueh‐Wen Chang, Cheng‐Hsu Yang, Teng‐Hung Yu, Yen‐Hsun Chen, Chi‐Ling Hang,
... the 30-day composite major adverse clinical outcomes (MACO) [advanced Killip score ≥ 3], severe congestive heart failure ( ... 0.0001) were independent predictors of 30-day MACO. Additionally, high ET-1 level (p = 0.0021) ... is a strong independent predictor of 30-day MACO after ST-segment elevated AMI treated with primary ... the 30-day composite major adverse clinical outcomes (MACO) [advanced Killip score ≥ 3], severe congestive heart failure ( ... 0.0001) were independent predictors of 30-day MACO. Additionally, high ET-1 level (p = 0.0021) ...
Tópico(s): Cardiovascular Function and Risk Factors
2005 - Elsevier BV | CHEST Journal
... about a primary school level social studies course, MACOS, which occurred in Queensland in 1977. The course ... order to show that the Queensland campaign against MACOS was similar to those which occurred in the ... years. A content analysis of fundamentalist writings and MACOS materials is described. The results show that fundamentalist writings and MACOS materials are diametrically opposed at the level of ... versions of social reality. The decision to ban MACOS (and SEMP later) can be understood then as ...
Tópico(s): Religious Education and Schools
1978 - SAGE Publishing | Australian Journal of Education
... colony-optimization based QoS-aware cross-layer routing (MACO-QCR) protocol has been proposed for inter-cluster ... objective functions. To obtain Pareto optimal solutions, the MACO-ACO uses an external archive method based on ... fitness values to the non-dominated solutions. Moreover, MACO-QCR adopts a cross layer approach that enables ... relay node selection. The simulation analysis shows that MACO-QCR has up to 10.5% and 6. ...
Tópico(s): Mobile Ad Hoc Networks
2020 - IEEE Sensors Council | IEEE Sensors Journal
Ihda Novia Indrajati, Indiah Ratna Dewi,
... to evaluate the performance of maleated castor oil (MACO) as plasticizer on natural rubber (NR), ethylene propylene ... were involving rheological, curing and swelling properties. The MACOs were prepared by an esterification reaction between castor ... has been made to evaluate the performance of MACO and conventional plasticizer (paraffinic oil for NR and ... showed that rubber (NR/EPDM/NBR) plasticized with MACO had given similar flow characteristic to conventional plasticizers. MACO exhibited slow curing, confirmed by higher t90, but ...
Tópico(s): Polymer crystallization and properties
2017 - IOP Publishing | IOP Conference Series Materials Science and Engineering
Vanessa Carmean, Marc Yonkers, Marco Tellez, Jason R. Willer, Gregory B. Willer, Ronald G. Gregg, Robert Geisler, Stephan C. F. Neuhauss, Angeles B. Ribera,
... We investigate a touch-insensitive zebrafish mutant, macho (maco), previously shown to have reduced sodium current amplitude ... by the mutation, knock-down of PigK phenocopies maco touch insensitivity and leads to reduced sodium current ( ... whether the genetic defect in pigk underlies the maco phenotype by overexpressing wild-type pigk in mutant ... wild-type pigk rescues the touch response in maco mutants. In addition, for maco mutants, expression of wild-type pigk restricted to ...
Tópico(s): Neurobiology and Insect Physiology Research
2015 - American Physiological Society | Journal of Neurophysiology
Subhankar Ghorui, Nil Ratan Bandyopadhyay, Dipa Ray, Suparna Sengupta, Tanusree Kar,
Maleated castor oil (MACO) was prepared and was used as biomodifier in unsaturated polyester resin (UPE)/fly ash composites. The prepared MACO was characterized for its molecular weight and viscosity. MACO was blended with UPE in three different ratios ... and curing was done by free radical polymerization. MACO was polymerized and crosslinked with UPE in situ ... in properties was significant. Incorporation of 5 wt% MACO was most effective compared to 10 and 15 ...
Tópico(s): Polymer Nanocomposites and Properties
2011 - Elsevier BV | Industrial Crops and Products
Paul G. Fitchett, William B. Russell,
... projects developed was Man: A Course of Study (MACOS) which sought to restructure social studies instruction by ... that contributed to the eventual demise of the MACOS project. The author proposes that federally funded MACOS challenged the "history‐as‐national‐progress" paradigm of ... purpose of social studies education. The study of MACOS's demise provides an insightful lesson on how ...
Tópico(s): Historical Geopolitical and Social Dynamics
2011 - Taylor & Francis | Paedagogica Historica
Nan Zhao, Zhilu Wu, Yaqin Zhao, Taifan Quan,
Mutated ant colony optimization (MACO) algorithm is proposed by introducing the mutation mechanism to the ACO algorithm, and is applied to the traveling salesman problem ( ... resulting in a bad steady state. The presented MACO algorithm can enlarge searching range and avoid local ... operation is simple to implement, the performance of MACO is superior with almost the same computational complexity. MACO is applied to TSP and multiuser detection, and via computer simulations it is shown that MACO has much better performance in solving these two ...
Tópico(s): Metaheuristic Optimization Algorithms Research
2009 - Elsevier BV | Expert Systems with Applications
Greg Shaffer, Florian Zettelmeyer,
... technology site, reviews the newest upgrade of the MacOS and writes that the new user interface is ... that they both express good news about the MacOS and thus they both can be expected to ... will lose because the good news about the MacOS will induce some consumers to choose Macs over ... consumers). We show that good news about the MacOS that is more relevant to Apple's core ... but harms CompUSA, while good news about the MacOS that is more relevant to Apple's noncore ...
Tópico(s): Digital Platforms and Economics
2002 - Institute for Operations Research and the Management Sciences | Marketing Science
Igor G. Morgunov, Paul A. Srere,
... 179Crossref PubMed Scopus (37) Google Scholar), mitochondrial aconitase (mACO) with CS (13Srere P.A. Sherry A.D. ... 201-217Google Scholar), NAD-dependent isocitrate dehydrogenase with mACO (14Tyiska R.L. Williams J.S. Brent L. ... The same enzyme modeling strategy was extended with mACO, and recent computer graphic modeling studies provide a putative complex of porcine mACO·CS·mMDH complex (20Vélot C. Mixon M.B. ... shows an electrostatically favorable channel between CS and mACO as well as the already reported mMDH-CS ...
Tópico(s): Amino Acid Enzymes and Metabolism
1998 - Elsevier BV | Journal of Biological Chemistry
Jun-Dong Lu, Mei-Lin Sun, Peili, Xiaopeng Wang,
... 80 mg/kg b.w) were administrated in MACO rats. Results showed NBP improves infarct volume, attenuates ... SOD) and the ratio of GSH/GSSG in MACO rats increased. MACO caused non-heme iron accumulation in the brain ... Perl’s staining confirmed NBP attenuates ferroptosis in MACO rats. The protein expressions of SCL7A11 and glutathione ...
Tópico(s): Cancer-related molecular mechanisms research
2023 - SAGE Publishing | Journal of Investigative Medicine
Lin Shi, Zhi‐Hui Zhan, Di Liang, Jun Zhang,
... DEVD model, a memory-based ant colony optimization (MACO) approach is developed. MACO maintains a memory archive to store the historically ... procedure is designed to enhance the performance. The MACO algorithm is applied to a set of dynamic ... request and EV sizes. Experimental results show that MACO generally outperforms the first-come-first-served approach ...
Tópico(s): Electric and Hybrid Vehicle Technologies
2022 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Intelligent Transportation Systems
Xiao Wei, Junqi Ge, Fei Gao, Fengbiao Chen, Wen‐Xiong Zhang, Jiang Zhong, Cong Lin, Liang Shen,
... alamine and bio-based modified acetoacetylated castor oil (MACO) containing acetoacetate moieties as well as acid groups. The MACO was synthesized using a transesterification reaction and thiol- ... on the different ratios of acid groups of MACO, three coating materials were prepared from an amine- ... with higher ratio of acid groups from the MACO. Hence, the ratio of acid groups in the ...
Tópico(s): Carbon dioxide utilization in catalysis
2021 - Elsevier BV | European Polymer Journal
J. A. Molina‐Bolívar, F. Galisteo‐González, C. Carnero Ruiz, Marta Medina‐O’Donnell, Antonio Martı́nez, Andrés Parra,
... It was found that the coumarin-maslinic derivative (MaCo) forms an excellent fluorescence resonance energy transfer (FRET) ... measuring the distance between donor (Trp) and acceptor (MaCo) through Förster energy transfer mechanism. Displacement experiments confirmed that MaCo binds to subdomain IIA of HSA with independence ... 45 °C, the fluorescence emission maximum of HSA-MaCo complex decreased, whereas in the range 45 °C- ...
Tópico(s): Lanthanide and Transition Metal Complexes
2019 - Elsevier BV | Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
Sankaramoorthy Muthubalaji, Veluchamy Malathi,
... networks. The combination of multiobjective ant colony optimization (MACO) and the bacterial foraging optimization algorithm (BFOA) is ... to overcome this problem, the combination of hybrid MACO and BFOA algorithms is applied in this analysis ... a 5-bus network show that the proposed MACO with BFOA method can efficiently ensure the power ...
Tópico(s): Electric Power System Optimization
2017 - Scientific and Technological Research Council of Turkey (TUBITAK) | TURKISH JOURNAL OF ELECTRICAL ENGINEERING & COMPUTER SCIENCES
Produção Nacional
Mairton Gomes da Silva, Tales Miler Soares, I. de S. Oliveira, Jean Cleber da Silva Santos,
... nutritiva (2,75 e 5,50 L por maço de 24 plantas) e quatro níveis de salinidade ... matéria fresca e seca da parte aérea do maço de plantas, das folhas e do caule foram ... massa de matéria fresca da parte aérea do maço de plantas. Assim, a combinação de água doce ... massa de matéria fresca da parte aérea do maço de plantas em 30,0% em relação à ...
Tópico(s): Growth and nutrition in plants
2015 - | Revista Brasileira de Agricultura Irrigada
Xiaoping Liu, Xia Li, Xun Shi, Kangning Huang, Yilun Liu,
... type ant colony optimization optimal multiple land allocation (MACO-MLA) model was successfully applied to a case ... overall suitability, compactness, and cost. Comparison indicates that MACO-MLA can yield better performances than the simulated ... genetic algorithm (GA) methods. It is found that MACO-MLA has an improvement of the total utility ...
Tópico(s): Smart Parking Systems Research
2012 - Taylor & Francis | International Journal of Geographical Information Science