Produção Nacional
Revisado por pares
Dielle Monteiro Teixeira, Paula Katharine de Pontes Spada, Lena Líllian Canto de Sá Morais, Túlio Machado Fumian, Ian Carlos Gomes de Lima, Darleise de Souza Oliveira, Renato da Silva Bandeira, Tereza Cristina Monteiro Gurjão, Maísa Silva de Sousa, Joana D’Arc Pereira Mascarenhas, Yvone Benchimol Gabbay,
This study investigated the presence of norovirus (NoV) GI and GII in environmental samples from the northern region of Brazil. Water samples were collected monthly (November 2008/October 2010) from different sources and sewage and concentrated by the adsorption-elution method. The NoV investigation used molecular methods followed by sequencing reactions. The general positivity for NoV was 33.9% (57/168). Considering the results obtained only in the semi-nested RT-PCR (reverse transcription polymerase ...
Tópico(s): Parasitic Infections and Diagnostics
2016 - UWA Publishing | Journal of Water and Health
Produção Nacional
Revisado por pares
Joyce Ferreira da Costa Guerra, Poliane Silva Maciel, Isabel Cristina Mallosto Emerich de Abreu, Renata Rebeca Pereira, Maísa Silva, Leandro de Morais Cardoso, Helena Maria Pinheiro-Sant’Ana, Wanderson Geraldo de Lima, Marcelo Estáquio Silva, Maria Lúcia Pedrosa,
Polyphenols, especially anthocyanins, have been considered promising for the prevention of nonalcoholic fatty liver disease (NAFLD). This study investigated whether açai (Euterpe oleracea Mart.), a source of anthocyanins and recognized as one of the new "superfruits", could alleviate high-fat diet (HFD)-induced NAFLD in mice. In HFD mice, aqueous açai extract (AAE) administration (3 g/kg) for six weeks improved insulin resistance index and increased adiponectin mRNA expression in adipose tissue and serum ...
Tópico(s): Adipose Tissue and Metabolism
2015 - Elsevier BV | Journal of Functional Foods
Produção Nacional
Revisado por pares
Ingrid Christiane Silva, Bruna Teles Pinheiro, Akim Felipe Santos Nobre, Jaciana Lima Coelho, Cássia Cristine Costa Pereira, Louise de Souza Canto Ferreira, Camila Pâmela Santos de Almeida, Maria de Nazaré do Socorro de Almeida Viana, Danilo Souza de Almeida, Jairo Ribeiro Falcão, Yago Costa Vasconcelos dos Santos, Marcos William Leão de Araújo, Mariza da Silva Borges, Lisandra Duarte Nascimento, Lorena Saldanha Valentim, Jorge Casseb, Carlos Araújo da Costa, Maísa Silva de Sousa,
The spread of the HTLV infection in families living in the metropolitan area of Belém, Pará, Brazil, and the lack of studies in the general population requires studies to better understand its prevalence in the region.An anti-HTLV-1/HTLV-2 antibodies test was carried out on random adults in public places in Belém between November 2014 and November 2015. A proviral DNA test detected if the person was infected, and then a clinical evaluation and an intrafamilial investigation were carried out.Of the ...
Tópico(s): Rural Development and Agriculture
2018 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
Carolina Rosadas, Marzia Puccioni‐Sohler, Augusto César Penalva de Oliveira, Jorge Casseb, Maísa Silva de Sousa, Graham P. Taylor,
Adult T-cell leukaemia/lymphoma (ATL), caused by human T-cell lymphotropic virus type 1 (HTLV-1) infection has a median survival of 6–8 months. In Japan the incidence of ATL is about 10 times higher than HTLV-1-associated myelopathy (HAM) whilst in other regions the incidence of these consequences is similar. Brazil has a high prevalence of HTLV-1 with HAM cohorts described, but reports of ATL are sparse, leading to the concept that the incidence of ATL is low. Here, the number of ATL cases in Brazil ...
Tópico(s): Animal Disease Management and Epidemiology
2019 - Wiley | British Journal of Haematology
Produção Nacional
Revisado por pares
Leonardo Miranda dos Santos, Maria Renata Mendonça dos Santos Vieira, Jéssica Fernanda Galdino Oliveira, Josinaide Quaresma Trindade, Danielle Murici Brasiliense, Stephen F. Ferrari, Mihoko Yamamoto Tsutsumi, Hellen Thaís Fuzii, Edivaldo Costa Sousa, Edna Aoba Yassui Ishikawa, Ricardo Ishak, Maísa Silva de Sousa,
Background Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection (STI) in the world. Approximately 80% of infected women are asymptomatic, although this infection can lead to serious complications in the female reproductive tract. Few data on Chlamydia infection are available in rural Amazonian communities. Objectives To evaluate the prevalence of sexual C. trachomatis infection in women from Marajó Archipelago communities in the Amazon region of Brazil and to identify ...
Tópico(s): Adolescent Sexual and Reproductive Health
2018 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Daniel Valim Duarte, Rodrigo Covre Vieira, Elza Baía de Brito, Maria da Conceição Nascimento Pinheiro, Jeniffer do Socorro Valente Monteiro, Mário Diego Rocha Valente, Edna Aoba Yassui Ishikawa, Hellen Thaís Fuzii, Maísa Silva de Sousa,
Purpose The aim of this study was to evaluate the overall and type-specific prevalence of human papillomavirus (HPV) infection among females living in riverside communities in the state of Pará, in the Eastern Brazilian Amazon. These communities are inhabited by low-income people, and are accessible only by small boats. Cervical cytology and risk factors for HPV infection were also assessed. Methods Cervical samples from 353 women of selected communities were collected both for Papanicolau (Pap) test ...
Tópico(s): Hepatitis B Virus Studies
2017 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Waleska Dornas, Leonardo Máximo Cardoso, Maísa Silva, Natalia Machado, Deoclécio Alves Chianca, Andréia Carvalho Alzamora, Wanderson Geraldo de Lima, Vincent Lagente, Marcelo E. Silva,
There is evidence that diets rich in salt or simple sugars as fructose are associated with abnormalities in blood pressure regulation. However, the mechanisms underlying pathogenesis of salt- and fructose-induced kidney damage and/or consequent hypertension yet remain largely unexplored. Here, we tested the role of oxidative state as an essential factor along with high salt and fructose treatment in causing hypertension. Fischer male rats were supplemented with a high-fructose diet (20% in water) ...
Tópico(s): Alcohol Consumption and Health Effects
2017 - Nature Portfolio | Scientific Reports
Produção Nacional
Leonardo Miranda dos Santos, Wlyana Lopes Ulian, Josinaide Quaresma Trindade, Francisca Dayse Martins de Sousa, Jéssica Fernanda Galdino Oliveira, Cássia Cristine Costa Pereira, Danielle Murici Brasiliense, Benedito Antônio dos Prazeres, Mihoko Yamamoto Tsutsumi, Edna Aoba Yassui Ishikawa, Maísa Silva de Sousa,
OBJETIVOS: Descrever a prevalência e os fatores associados à infecção endocervical por Chlamydia trachomatis em estudantes de uma universidade da capital e de três de seus campi do interior do estado do Pará, Amazônia, Brasil.
Tópico(s): Health and Wellbeing Research
2017 - | Revista Pan-Amazônica de Saúde
Produção Nacional
Revisado por pares
Letícia Teixeira de Siqueira Valadares, Luíza Siqueira Barreto de Souza, Valdir Alves Salgado Júnior, L Bonomo, Leandro Roberto de Macedo, Maísa Silva,
Abstract Background A cluster of interconnected cardiometabolic risk factors characterizes metabolic Syndrome (MS). The prevalence of MS is increasing worldwide, but there is not a meta-analysis of this prevalence in the Brazilian population. We aimed to determine the prevalence of metabolic syndrome among adult general population in Brazil through a meta‑analysis study. Methods Original research studies were searched at PubMed, Scopus, Web of Science, and SciELO databases, from 2011 to 2021. We ...
Tópico(s): Diabetes Management and Research
2022 - BioMed Central | BMC Public Health
Produção Nacional
Luana Nepomuceno Gondim Costa Lima, Maísa Silva de Sousa, Karla Valéria Batista Lima,
Objetivo: Auxiliar no entendimento da COVID-19 em relação à origem do SARS-CoV-2, suas descobertas genômicas, patogenia, possíveis hospedeiros primários e intermediários, além da comparação com outros coronavírus. Metodos: foram utilizadas as bases de dados Scientific Eletronic Library Online e PubMed, com artigos de revisão e originais, em língua portuguesa e inglesa, pesquisados no período de 05 de março a 10 de abril de 2020, adotando os seguintes descritores: SARS-CoV, COVID-19, coronavirus, ...
Tópico(s): Virus-based gene therapy research
2020 - CENTRO UNIVERSITÁRIO CHRISTUS | Journal of Health & Biological Sciences
Produção Nacional
Revisado por pares
Renata Rebeca Pereira, Isabel Cristina Mallosto Emerich de Abreu, Joyce Ferreira da Costa Guerra, Nara Nunes Lage, Juliana Márcia Macedo Lopes, Maísa Silva, Wanderson Geraldo de Lima, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa,
Açai (Euterpe oleracea Mart.), a fruit from the Amazon region, has emerged as a promising source of polyphenols. Açai consumption has been increasing owing to ascribed health benefits and antioxidant properties; however, its effects on hepatic injury are limited. In this study, we evaluated the antioxidant effect of filtered açai pulp on the expression of paraoxonase (PON) isoforms and PON1 activity in rats with nonalcoholic fatty liver disease (NAFLD). The rats were fed a standard AIN-93M (control) ...
Tópico(s): Apelin-related biomedical research
2016 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity
Produção Nacional
Revisado por pares
Maísa Silva, Joyce Ferreira da Costa Guerra, Ana Flávia Santos Sampaio, Wanderson Geraldo de Lima, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa,
The objective of this study was to investigate the effects of iron dextran on lipid metabolism and to determine the involvement of oxidative stress. Fischer rats were divided into two groups: the standard group (S), which was fed the AIN-93M diet, and the standard plus iron group (SI), which was fed the same diet but also received iron dextran injections. Serum cholesterol and triacylglycerol levels were higher in the SI group than in the S group. Iron dextran was associated with decreased mRNA levels ...
Tópico(s): Cholesterol and Lipid Metabolism
2015 - Hindawi Publishing Corporation | BioMed Research International
Produção Nacional
Revisado por pares
Rodrigo Covre Vieira, Jeniffer do Socorro Valente Monteiro, Estéfane Primo Manso, Maria Renata Mendonça dos Santos, Mihoko Yamamoto Tsutsumi, Edna Aoba Yassui Ishikawa, Stephen F. Ferrari, Karla Valéria Batista Lima, Maísa Silva de Sousa,
Human papillomavirus (HPV) infection is associated with cervical cancer, the most frequent cancer in women from northern Brazil. Assessment of the short-term impact of HPV vaccination depends on the availability of data on the prevalence of type-specific HPV in young women in the pre-immunization period, although these data are currently unavailable for the study region. The aim of this study was to estimate the distribution of all mucosal HPV genotypes, including low- and high-risk HPV types, in ...
Tópico(s): Hepatitis B Virus Studies
2015 - BioMed Central | Infectious Agents and Cancer
Produção Nacional
Revisado por pares
Waleska Dornas, Maísa Silva, Ricardo Luiz de Oliveira Tavares, Wanderson Geraldo de Lima, Rinaldo Cardoso dos Santos, Maria Lúcia Pedrosa, Marcelo E. Silva,
Considering the growing body of evidence that indicates the contribution of superoxide anions (O2) and other reactive oxygen species (ROS) to the development of hypertension, we assessed whether animal models of hypertension have a benefic effect with tempol, a superoxide dismutase mimetic, to help augment the design of future studies.Studies published between July 1998 and December 2012 on blood pressure (BP) in different hypertensive models were obtained after an electronic and manual search of PubMed. ...
Tópico(s): Free Radicals and Antioxidants
2014 - Lippincott Williams & Wilkins | Journal of Hypertension
Produção Nacional
Isabel Cristina Mallosto Emerich de Abreu, Joyce Ferreira da Costa Guerra, Renata Rebeca Pereira, Maísa Silva, Wanderson Geraldo de Lima, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa,
Objective : This study aimed to determine whether a hypercholesterolemic diet induces hepatic steatosis, alterations in mRNA expression of NADPH oxidase subunits, and antioxidant defenses.Materials and methods : Fischer rats were divided into two groups of eight animals according to the treatment, control (C) and hypercholesterolemic diet (H). Those in group C were fed a standard diet (AIN-93M), and those of the group H were fed a hypercholesterolemic diet (25% soybean oil and 1% cholesterol).Results : The ...
Tópico(s): Pancreatic function and diabetes
2014 - Editora da Universidade de São Paulo | Arquivos Brasileiros de Endocrinologia & Metabologia
Produção Nacional
Revisado por pares
Ana Flávia Santos Sampaio, Maísa Silva, Waleska Dornas, Daniela Caldeira Costa, Marcelo E. Silva, Rinaldo Cardoso dos Santos, Wanderson Geraldo de Lima, Maria Lúcia Pedrosa,
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2014 - Springer Science+Business Media | BioMetals
Produção Nacional
Revisado por pares
Carlos Araújo da Costa, Karen Cristini Yumi Ogawa Furtado, Louise de Souza Canto Ferreira, Danilo de Souza Almeida, Alexandre da Costa Linhares, Ricardo Ishak, Antônio Carlos Rosário Vallinoto, José Alexandre Rodrigues de Lemos, Luisa Carício Martins, Edna Aoba Yassui Ishikawa, Rita Catarina Medeiros Sousa, Maísa Silva de Sousa,
Background HTLV-1 is a retrovirus that causes lymphoproliferative disorders and inflammatory and degenerative diseases of the central nervous system in humans. The prevalence of this infection is high in parts of Brazil and there is a general lack of public health care programs. As a consequence, official data on the transmission routes of this virus are scarce. Objective To demonstrate familial aggregation of HTLV infections in the metropolitan region of Belém, Pará, Brazil. Method A cross-sectional ...
Tópico(s): Vector-Borne Animal Diseases
2013 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Danielle de Lima Ávila, Glaucy Rodrigues de Araújo, Maísa Silva, Pedro Henrique de Amorim Miranda, Mirla Fiuza Diniz, Maria Lúcia Pedrosa, Marcelo Eustáquio Silva, Wanderson Geraldo de Lima, Daniela Caldeira Costa,
Background and Aims.It is believed that oxidative stress plays a role in the pathogenesis of diabetes mellitus.Several strategies have been developed with the objective of minimizing diabetic complications.Among these, inhibitors of dipeptidyl peptidase-IV (DPP-IV), which act by blocking degradation of incretin hormones, glucagon-like peptide hormone (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), have been the focus of many studies.It is known that, among the effects of incretins, ...
Tópico(s): Diabetes Treatment and Management
2013 - Elsevier BV | Archives of Medical Research
Produção Nacional
Revisado por pares
Jones Anderson Monteiro Siqueira, Alexandre da Costa Linhares, Thaís Cristina Nascimento de Carvalho, Glicélia Cruz Aragão, Darleise de Souza Oliveira, Mirleide Cordeiro dos Santos, Maísa Silva de Sousa, Maria Cleonice Aguiar Justino, Joana D’Arc Pereira Mascarenhas, Yvone Benchimol Gabbay,
Abstract Noroviruses are the leading cause of epidemic, non‐bacterial outbreaks of acute gastroenteritis, and are also a major cause of sporadic acute gastroenteritis in infants. The aim of the present study was to identify norovirus infections in children not infected by rotavirus admitted to hospital for acute gastroenteritis in Belém. A total of 348 fecal specimens were obtained from children with diarrhea aged less than 5 years, all of whom had tested negative for rotavirus, between May 2008 ...
Tópico(s): Hepatitis Viruses Studies and Epidemiology
2013 - Wiley | Journal of Medical Virology
Produção Nacional
Revisado por pares
Waleska Dornas, Wanderson Geraldo de Lima, Rinaldo Cardoso dos Santos, Joyce Ferreira da Costa Guerra, Melina Oliveira de Souza, Maísa Silva, Lorena Souza e Silva, Mirla Fiuza Diniz, Marcelo Eustáquio Silva,
In this study we investigated the hypothesis that a high-salt diet to hyperinsulinemic rats might impair antioxidant defense owing to its involvement in the activation of sodium reabsorption to lead to higher oxidative stress. Rats were fed a standard (CON), a high-salt (HS), or a high-fructose (HF) diet for 10 weeks after which, 50% of the animals belonging to the HF group were switched to a regimen of high-fructose and high-salt diet (HFS) for 10 more weeks, while the other groups were fed with their ...
Tópico(s): Biochemical effects in animals
2013 - Elsevier BV | The Journal of Nutritional Biochemistry
Produção Nacional
Revisado por pares
Maísa Silva, L Bonomo, Riva de Paula Oliveira, Wanderson Geraldo de Lima, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa,
This study evaluated the effects of the interaction of diabetes and a carbonyl iron supplemented on hepatic and pancreatic tissues, oxidative stress markers and liver peroxisome proliferator-activated receptor-α expressions. Hamsters were divided: Control which received a standard AIN 93 diet; Control Iron, composed of control animals that received a diet with 0.83% carbonyl iron; Diabetic, composed of animals that received a injection of streptozotocin (50 mg/kg, intraperitoneal) on day 35; and ...
Tópico(s): Liver Disease Diagnosis and Treatment
2011 - Society for Free Radical Research Japan | Journal of Clinical Biochemistry and Nutrition
Produção Nacional
Maísa Silva, Wanderson Geraldo de Lima, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa,
OBJETIVO: Este estudo avaliou os efeitos da estreptozotocina nos perfis glicêmico e lipídico e marcadores de estresse oxidativo em hamsteres. MATERIAIS E MÉTODOS: Hamsteres machos Golden Syrian foram divididos em dois grupos: grupo diabético (D), que recebeu uma única injeção de estreptozotocina (STZ - 50 mg/kg), e grupo controle (C), que recebeu injeção de tampão citrato. Os animais foram eutanasiados após 10 dias de experimento e o sangue, o fígado e rins foram coletados. RESULTADOS: O grupo diabético ...
Tópico(s): Biochemical Acid Research Studies
2011 - Editora da Universidade de São Paulo | Arquivos Brasileiros de Endocrinologia & Metabologia
Produção Nacional
Revisado por pares
Jerusa Marilda Arantes, Amanda Fortes Francisco, Paula Melo de Abreu Vieira, Maísa Silva, Márcio Sobreira Silva Araújo, Andréa Teixeira‐Carvalho, Maria Lúcia Pedrosa, Cláudia Martins Carneiro, Washington Luíz Tafuri, Olindo Assis Martins-Filho, Silvana Maria Elói-Santos,
Tópico(s): Parasites and Host Interactions
2011 - Elsevier BV | Experimental Parasitology
Produção Nacional
Revisado por pares
Ana Roberta Fusco da Costa, Maria Luiza Diniz de Sousa Lopes, Ismari Perini Furlaneto, Maísa Silva de Sousa, Karla Valéria Batista Lima,
This study utilized the hsp65 polymerase chain reaction restriction analysis (PRA) method in the identification of nontuberculous mycobacteria (NTMs) isolated in a Brazilian mycobacteria laboratory. NTM isolates from clinical specimens collected from 192 patients were characterized using the hsp65 PRA method and analyzed using both 16S rRNA and hsp65 gene sequencing. Only 30% of the NTM strains were correctly identified through PRA, though the suggested inclusion of an additional restriction enzyme ...
Tópico(s): Genomics and Phylogenetic Studies
2010 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Produção Nacional
Revisado por pares
Melina Oliveira de Souza, Maísa Silva, Marcelo Eustáquio Silva, Riva de Paula Oliveira, Maria Lúcia Pedrosa,
We investigated the antioxidant potential and hypocholesterolemic effects of acai (Euterpe oleracea Mart.) pulp ingestion in rats fed a standard or hypercholesterolemic diet.Female Fischer rats were fed a standard AIN-93 M diet (control) or a hypercholesterolemic diet that contained 25% soy oil and 1% cholesterol. The test diet was supplemented with 2% acai pulp (dry wt/wt) for control (group CA) and hypercholesterolemic rats (group HA) for 6 wk. At the end of the experimental period, rats were sacrificed ...
Tópico(s): Phytochemicals and Antioxidant Activities
2009 - Elsevier BV | Nutrition
Produção Nacional
Revisado por pares
Ana Roberta Fusco da Costa, Maria Luiza Diniz de Sousa Lopes, Sylvia Cardoso Leão, Maria Paula da Cruz Schneider, Maísa Silva de Sousa, Philip Noël Suffys, Tereza Cristina de Oliveira Corvelo, Karla Valéria Batista Lima,
We isolated 44 strains of rapidly growing mycobacteria (RGM) from 19 patients with pulmonary infections assisted at the Instituto Evandro Chagas (Pará, Brazil) from 2004 to 2007. Identification at the species level was performed by PCR restriction fragment length polymorphism analysis (PRA) of a 441 bp hsp65 fragment and partial 16S rRNA, hsp65, and rpoB gene sequencing. Genotyping by PRA yielded 3 digestion patterns: one identical to Mycobacterium abscessus type I (group I); another to M. abscessus ...
Tópico(s): Tuberculosis Research and Epidemiology
2009 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Produção Nacional
Revisado por pares
Amanda Fortes Francisco, Paula Melo de Abreu Vieira, Jerusa Marilda Arantes, Maria Lúcia Pedrosa, Helen Rodrigues Martins, Maísa Silva, Vanja Maria Veloso, Marta de Lana, Maria Terezinha Bahia, Washington Luíz Tafuri, Cláudia Martins Carneiro,
Iron chelators have been employed in various studies aimed at evaluating the relationship between the iron status of the host and the development of infection. In the present study, the effects of benznidazole (BZ) therapy in combination with the iron chelator desferrioxamine (DFO) on the development of infection in mice inoculated with Trypanosoma cruzi Y strain have been investigated. Infected mice treated with DFO presented lower levels of parasitemia compared with infected untreated animals. Therapy ...
Tópico(s): Helminth infection and control
2008 - Elsevier BV | Experimental Parasitology
Produção Nacional
Revisado por pares
Maísa Silva, Marcelo E. Silva, Heberth de Paula, Cláudia Martins Carneiro, Maria Lúcia Pedrosa,
The objective of this study was to investigate the effect of iron overload with a hyperlipidemic diet on the histologic feature of hepatic tissue, the lipid and glycemic serum profiles, and the markers of oxidative damage and stress in a rat model. Twenty-four male Fischer rats, purchased from Experimental Nutrition Laboratory, Federal University of Ouro Preto, were assigned to 4 equal groups, 2 were fed a standard cholesterol-free diet (group C or control and CI or control with iron) containing ...
Tópico(s): Folate and B Vitamins Research
2008 - Elsevier BV | Nutrition Research
Maísa Silva de Oliveira Neves, J. Périès, Ali Saı̈b,
This report describes integration sites of human foamy virus (HFV) in chronically infected BALB/c murine cells that we isolated by inverse PCR and characterized. We show that integration of HFV proviral genome mainly occurs in highly repetitive and/or transcriptionally active regions and leads to the formation of a 4-bp cellular direct repeat sequence at each provirus extremity. As non-random deletions were previously described in the HFV be/1 transactivator gene as well as in the long terminal repeats ( ...
Tópico(s): Viral Infections and Immunology Research
1998 - Elsevier BV | Research in Virology
Produção Nacional
Revisado por pares
Emilyn Costa Conceição, Nalin Rastogi, David Couvin, Maria Luiza Diniz de Sousa Lopes, Ismari Perini Furlaneto, Harrison Magdinier Gomes, Sidra Ezídio Gonçalves Vasconcellos, Philip Noël Suffys, Maria Paula Cruz Schneider, Maísa Silva de Sousa, Christophe Sola, Ricardo José de Paula Souza e Guimarães, Rafael Silva Duarte, Karla Valéria Batista Lima,
There is only scarce information available on genotypic diversity of the Mycobacterium tuberculosis complex (MTBC) clinical isolates circulating in the Northern part of Brazil, a relatively neglected region regarding research on tuberculosis. We therefore characterized 980 MTBC clinical isolates from the state of Pará, by spoligotyping and data was compared with patterns from around the world, besides analyzing drug susceptibility, and collecting sociodemographic data. We also performed 24 loci MIRU- ...
Tópico(s): Infectious Diseases and Tuberculosis
2017 - Elsevier BV | Infection Genetics and Evolution