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Andrew Robson, David Harries, Sam Gustin, Roy Child, Barney Spender, John G. Horton, Raymond Snoddy Media Editor, Roy Albinson, Donald Bird, Andrew Pierce, DJM, Mary Killen, Martin Walter, Mark Henderson and Steve Bird, Adam Sherwin Media Reporter, Sarah Potter, Dalya Alberge Arts Correspondent and Helen Nugent, Buck Rutledge, Robert Thicknesse, Richard Hobson, J. Rookwood, Philip Howard, Hilary Finch, David Chater, Janet Coates Jones, Suna Erdem, Jeremy Kingston, James Bone, Alison Kervin, Alexandra Frean Social Affairs Correspondent, Philip Warner, Elizabeth Judge, Gabrielle Starkey, James Hider, Jeremy Whittle, Kevin Eason, Geoff Brown, Sam Lister, Andrew Norfolk, Geoff Parsons, Antonia Senior, Ben Webster, Lewis Smith and Russell Hotten, Pat Gibson, Jeremy Greenfield, Jennai Cox Fitness Editor, Tom Bawden, Steve Bird, Riccardo Orizio, Rory Watson, Gary Jacob, Jon Ritman, Tim Reid, Toby Moore, Peter Vesterdorf (EU consultant), Dan Sabbagh, John Smart, Phoebe Greenwood, Richard Ford Home Correspondent, Alan Hamilton, Stephen Farrell, Jenny MacArthur, Alan Warren, Nick Wyke, Julian Elliott, Richard Lloyd Parry, Jonathan Richards, Stefanie Marsh, Michael Fishman, Stephen Morse, Barry Johnston, Caroline Merrell Banking Correspondent, Angela Jameson, Julie Critchley, Hugh Murray, Mark Tweedle, Oliver Kay, Eric Moonman, Kerry Hutchinson, Acting Director, John Westerby, Rick Broadbent, Tom Baldwin, Mark Henderson Science Correspondent, John Starling, Simon de Bruxelles, John Hopkins Golf Correspondent, Joan Marston (Advocacy Officer), Rob Wright, Geoffrey Dean, John Lea, Susan Greenfield, Andrew Cockburn, David Powell Athletics Correspondent, Abi Newman, Raymond Keene, Philip Whiteley, Roy Setter, Rosemary Bennett Deputy Political Editor, Beryl Dixon, Caroline Merrell, Neville Scott, Chris Campling, Bronwen Maddox, Russell Hotten, Suzanne Leonard, Richard Owen, Anthony Browne Environment Editor, Christopher Martin-Jenkins Chief Cricket Correspondent, Oliver August, Nick Hasell, David Hands Rugby Correspondent, Nell Harman Tennis Correspondent, Oliver August and Melissa Kite, Matthew Brace, Craig Lord, Mel Webb, Des Dearlove, Anjana Ahuja, Glen Owen Education Correspondent, Ingrid Mansell, Michael Austin, Alan Lee, Peter Riddell, Abigail Rayner and Sam Gustin, Guy Thornton, Tony Dawe, David Charter Chief Political Correspondent, Richard Miles, Catherine Philp, Martin Waller, Michael Horsnell, Chris Ayres, Lisa Verrico, Christopher Irvine, Carl Mortished International Business Editor, Benedict Nightingale, Stephen Dalton, Valerie Elliott and Adam Fresco, David Powell, Bill Edgar, Michael Evans, Alan Lee Racing Correspondent, Sally Patten, Michael Evans, Tom Baldwin and Raymond Snoddy, Patience Wheatcroft, Mike Norris,

... Manager Multiple Display Advertising Items Jubilee High School Malco Stores Ltd Veredus Spencer Stuart CPS The Times ...

2003 - Gale Group | TDA

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Eva‐Juliane Vollstedt, Susen Schaake, Katja Lohmann, Shalini Padmanabhan, Alexis Brice, Suzanne Lesage, Christelle Tesson, Marie Vidailhet, Isabel Wurster, F. Hentati, Anat Mirelman, Nir Giladi, Karen Marder, Cheryl Waters, Stanley Fahn, Meike Kasten, Norbert Brüggemann, Max Borsche, Tatiana Foroud, Eduardo Tolosa, Alícia Garrido, Grazia Annesi, Monica Gagliardi, Maria Bozi, Leonidas Stefanis, Joaquim J. Ferreira, Leonor Correia Guedes, Micol Avenali, Simona Petrucci, Lorraine N. Clark, E. Yu. Fedotova, Natalya Abramycheva, Victoria Álvarez, Manuel Menéndez‐González, S. Jesús Maestre, Pilar Gómez‐Garre, Pablo Mir, Andrea Carmine Belin, Caroline Ran, Chin‐Hsien Lin, Ming‐Che Kuo, David Crosiers, Zbigniew K. Wszołek, Owen A. Ross, Joseph Jankovic, Kenya Nishioka, Manabu Funayama, Jordi Clarimón, Caroline H. Williams‐Gray, Marta Camacho, Mario Cornejo‐Olivas, Luis Torres-Ramírez, Yih‐Ru Wu, Guey‐Jen Lee‐Chen, Ana Morgadinho, Teeratorn Pulkes, Pichet Termsarasab, Daniela Berg, Gregor Kuhlenbäumer, Andrea A. Kühn, Friederike Borngräber, Giuseppe De Michele, Anna De Rosa, Alexander Zimprich, Andreas Puschmann, George D. Mellick, Jolanta Dorszewska, Jonathan Carr, Rosangela Ferese, Stefano Gambardella, Bruce A. Chase, Katerina Markopoulou, Wataru Satake, Tatsushi Toda, Malco Rossi, Marcelo Merello, Timothy Lynch, Diana A. Olszewska, Shen‐Yang Lim, Azlina Ahmad‐Annuar, Ai Huey Tan, Bashayer Al‐Mubarak, Haşmet Hanağası, Dariusz Koziorowski, Sibel Ertan, Gençer Genç, Patrícia de Carvalho Aguiar, Melinda Barkhuizen, Márcia Mattos Gonçalves Pimentel, Rachel Saunders‐Pullman, Bart van de Warrenburg, Susan Bressman, Mathias Toft, Silke Appel‐Cresswell, Anthony E. Lang, Matěj Škorvánek, Agnita J.W. Boon, Rejko Krüger, Esther Sammler, Vítor Tumas, Baorong Zhang, Gaëtan Garraux, Sun Ju Chung, Yun Joong Kim, Juliane Winkelmann, Carolyn M. Sue, Eng‐King Tan, Joana Damásio, Péter Klivényi, Vladimir Kostić, David Arkadir, Mika H. Martikainen, Vanderci Borges, Jens Michael Hertz, Laura Brighina, Mariana Spitz, Oksana Suchowersky, Olaf Rieß, Parimal Das, Brit Mollenhauer, Emilia Gatto, Maria Skaalum Petersen, Nobutaka Hattori, Ruey‐Meei Wu, С. Н. Иллариошкин, Enza Maria Valente, Jan Aasly, Anna Aasly, Roy N. Alcalay, Avner Thaler, Matthew J. Farrer, Kathrin Brockmann, Jean‐Christophe Corvol, Christine Klein,

Abstract Background As gene‐targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial‐ready cohorts is limited. Objective The objectives are to (1) establish an international cohort of affected and unaffected ...

Tópico(s): Nuclear Receptors and Signaling

2023 - Wiley | Movement Disorders

Revisão Acesso aberto Revisado por pares

Lara M. Lange, Paulina Gonzàlez‐Latapi, Rajasumi Rajalingam, Marina A.J. Tijssen, Darius Ebrahimi‐Fakhari, Carolin Gabbert, Christos Ganos, Rhia Ghosh, Kishore R. Kumar, Anthony E. Lang, Malco Rossi, Sterre van der Veen, Bart P.C. van de Warrenburg, Thomas T. Warner, Katja Lohmann, Christine Klein, Connie Marras,

Abstract In 2016, the Movement Disorder Society Task Force for the Nomenclature of Genetic Movement Disorders presented a new system for naming genetically determined movement disorders and provided a criterion‐based list of confirmed monogenic movement disorders. Since then, a substantial number of novel disease‐causing genes have been described, which warrant classification using this system. In addition, with this update, we further refined the system and propose dissolving the imaging‐based ...

Tópico(s): Glycogen Storage Diseases and Myoclonus

2022 - Wiley | Movement Disorders

Artigo Acesso aberto Revisado por pares

David Joseph Sullivan, Tom F. O’Mahony, Malco C. Cruz-Romero, Enda Cummins, Joseph P. Kerry, Michael A. Morris,

The objective of this study was to design, develop, and quantify the effectiveness of a simple method to facilitate the smart delivery of antimicrobial essential oils (EOs) via their absorption into a chemically bound high surface area support material. To this end, Santa Barbara Amorphous 15 (SBA-15) was functionalized by means of a post-synthetic reaction using (3-aminopropyl)triethoxysilane (APTES) to create an amine-terminated SBA-15 (SBA-APTES), and functionalization was confirmed by FTIR, TGA, ...

Tópico(s): Nanocomposite Films for Food Packaging

2021 - American Chemical Society | ACS Omega

Revisão Acesso aberto Revisado por pares

Malco Rossi, Sterre van der Veen, Marcelo Merello, Marina A.J. Tijssen, Bart van de Warrenburg,

A myriad of disorders combine myoclonus and ataxia. Most causes are genetic and an increasing number of genes are being associated with myoclonus-ataxia syndromes (MAS), due to recent advances in genetic techniques. A proper etiologic diagnosis of MAS is clinically relevant, given the consequences for genetic counseling, treatment, and prognosis.To review the causes of MAS and to propose a diagnostic algorithm.A comprehensive and structured literature search following PRISMA criteria was conducted ...

Tópico(s): Neurological disorders and treatments

2020 - Wiley | Movement Disorders Clinical Practice

Artigo Acesso aberto Revisado por pares

Sophia Elisseeva, Caroline Kelly, Malco C. Cruz-Romero, Alexander V. Zhdanov, Joe P. Kerry, Dmitri B. Papkovsky,

Microbial spoilage and foodborne diseases cause significant economic and productivity losses. There is a need for novel approaches and antimicrobial treatments to extend shelf life of products, improve quality and microbial safety, and reduce spoilage and waste, and new assessment methods. Traditional assays for testing the toxicity of antimicrobials are time consuming, labour intensive, give crude estimations of toxicity, and cannot analyse complex samples such as crude food homogenates. Using ...

Tópico(s): Analytical Chemistry and Sensors

2020 - Elsevier BV | Sensors and Actuators B Chemical

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Santiago Perez‐Lloret, Bart van de Warrenburg, Malco Rossi, Carmen Rodríguez–Blázquez, Theresa A. Zesiewicz, Jonas Alex Morales Saute, Alexandra Dürr, Masatoyo Nishizawa, Pablo Martínez‐Martín, Glenn T. Stebbins, Anette Schrag, Matěj Škorvánek,

We assessed the clinimetric properties of ataxia rating scales and functional tests, and made recommendations regarding their use.A systematic literature search was conducted to identify the instruments used to rate ataxia symptoms. The identified rating scales and functional ability tests were reviewed and ranked by the panel as "recommended," "suggested," or "listed" for the assessment of patients with discrete cerebellar disorders, using previously established criteria.We reviewed 14 instruments ( ...

Tópico(s): Mitochondrial Function and Pathology

2020 - Wiley | Movement Disorders

Artigo Acesso aberto Revisado por pares

Caroline Kelly, Elisa Santovito, Malco C. Cruz-Romero, Joe P. Kerry, Dmitri B. Papkovsky,

Two optical oxygen sensor systems we applied to monitor the evolution of meat spoilage in vacuum packaged (VP) samples of raw beef meat, which were produced at a large meat processing factory in Ireland under standard industrial settings on three different vacuum packaging machines. After packaging, the samples were put on storage at +1 °C for 90 days, while analysing their quality parameters. Residual oxygen levels and their time profiles, were measured non-destructively with disposable O2 sensors ...

Tópico(s): Water Quality Monitoring and Analysis

2019 - Elsevier BV | Sensors and Actuators B Chemical

Artigo Revisado por pares

Miguel Wilken, Verónica Bruno, Malco Rossi, Lucía Ameghino, Günther Deuschl, Marcelo Merello,

Hand position for rest tremor evaluation in PD is not standardized. We evaluated the sensitivity and specificity of different hand positions commonly used to evaluate rest tremor.Twenty patients with PD and rest tremor were included as cases and 20 patients with essential tremor without rest tremor as controls. Video and accelerometric recordings were conducted in semiprone, completely prone, and with hands hanging down from armrest positions. Three movement disorder specialists rated tremor in ...

Tópico(s): Glycogen Storage Diseases and Myoclonus

2019 - Wiley | Movement Disorders

Artigo Acesso aberto Revisado por pares

David J. Sullivan, Shafrina Azlin-Hasim, Malco C. Cruz-Romero, Enda Cummins, Joseph P. Kerry, Michael A. Morris,

The objective of this study was to evaluate the antimicrobial effects of benzoic and sorbic acid salt and their nano-solubilisates against planktonic and biofilm cultures of Staphylococcus aureus, Pseudomonas fluorescens and chicken microbiota. The antimicrobial activity was affected by the particle size of the organic acid antimicrobials, the Gram-strain, and the type of culture (planktonic or biofilm) used. The organic acid nano-solubilisates were significantly (P < 0.05) more effective compared to ...

Tópico(s): Nanocomposite Films for Food Packaging

2019 - Elsevier BV | Food Control

Artigo Acesso aberto Revisado por pares

Ciara M. O’Neill, Malco C. Cruz-Romero, Geraldine Duffy, Joseph P. Kerry,

The objective of this study was to determine the efficacy of HPP to accelerate marinade (piri-piri) absorption in pork chops and to study the effects on the physicochemical, sensory and microbiological characteristics during storage. HPP (300 MPa, 400 MPa or 500 MPa) and organic acids Inbac™ (0.3%) were used as hurdles to extend the shelf life. The results showed that HPP ≥ 400 MPa increased (P < 0.05) the marinade absorption which enhanced the flavour acceptability of the marinated pork chops. The piri- ...

Tópico(s): Identification and Quantification in Food

2019 - Elsevier BV | Food Packaging and Shelf Life

Artigo Acesso aberto

Ciara M. O’Neill, Malco C. Cruz-Romero, Geraldine Duffy, Joe P. Kerry,

The objective of this study was to assess the effect of griddle and steam cooking on the physicochemical and sensory characteristics of high pressure processed (HPP) piri-piri marinated pork chops (MPC). Raw MPC that were HPP at 400 MPa had higher (P < 0.05) marinade absorption compared to untreated samples. After cooking, griddled MPC were significantly (P < 0.05) darker, less red, less yellow, tougher and had higher cook loss compared to steam cooked samples. The appearance of the griddled MPC was preferred ...

Tópico(s): Identification and Quantification in Food

2019 - Elsevier BV | Innovative Food Science & Emerging Technologies

Revisão Acesso aberto Revisado por pares

Malco Rossi, Bettina Balint, Patricio Millar Vernetti, Kailash P. Bhatia, Marcelo Merello,

Dystonia and ataxia are manifestations of numerous disorders, and indeed, an ever-expanding spectrum of genes causing diseases that encompass dystonia and ataxia are discovered with the advances of genetic techniques. In recent years, a pathophysiological link between both clinical features and the role of the cerebellum in the genesis of dystonia, in some cases, has been proposed. In clinical practice, the genetic diagnosis of dystonia-ataxia syndromes is a major issue for genetic counseling, prognosis ...

Tópico(s): Mitochondrial Function and Pathology

2018 - Wiley | Movement Disorders Clinical Practice

Artigo Acesso aberto Revisado por pares

Koro de la Caba, Pedro Guerrero, Trang Sĩ Trung, Malco C. Cruz-Romero, Joseph P. Kerry, Joachim W. Fluhr, Marcus Maurer, Froukje Kruijssen, Amaya Albalat, Stuart W. Bunting, Steve Burt, Dave Little, Richard Newton,

Sustainable development is an overarching objective that requires an interdisciplinary approach in order to address the societal challenge concerning climate action, environment, resource efficiency and raw materials. In this context, valorization of abundant and available bio-wastes with high potential to manufacture value-added products is the first step to close the loop between waste and consumption in line with the main goal of the circular economy. In the last years, many research works have ...

Tópico(s): Consumer Packaging Perceptions and Trends

2018 - Elsevier BV | Journal of Cleaner Production

Artigo Revisado por pares

Shafrina Azlin-Hasim, Malco C. Cruz-Romero, Michael A. Morris, Enda Cummins, Joseph P. Kerry,

Antimicrobial coated films were produced by an innovative method that allowed surface modification of commercial low-density polyethylene films so that well-defined antimicrobial surfaces could be prepared. A Pluronic™ surfactant and a polystyrene-polyethylene oxide block copolymer were employed to develop modified materials. The Pluronic™ surfactant provided a more readily functionalised film surface, while block copolymer provided a reactive interface which was important in providing a route to ...

Tópico(s): Microplastics and Plastic Pollution

2018 - SAGE Publishing | Food Science and Technology International

Revisão Acesso aberto Revisado por pares

Malco Rossi, Verónica Bruno, Julieta Arena, Ángel Cammarota, Marcelo Merello,

Abstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or internal globus pallidus (GPi) represents an effective and universally applied therapy for Parkinson's disease (PD) motor complications. However, certain procedure‐related problems and unrealistic patient expectations may detract specialists from indicating DBS more widely despite significant clinical effects. Methods This review provides a pragmatic educational summary of the most conflicting postoperative management ...

Tópico(s): Parkinson's Disease and Spinal Disorders

2018 - Wiley | Movement Disorders Clinical Practice

Revisão Revisado por pares

Malco Rossi, Mathieu Anheim, Alexandra Dürr, Christine Klein, Michel Kœnig, Matthis Synofzik, Connie Marras, Bart P.C. van de Warrenburg,

ABSTRACT The recessive cerebellar ataxias are a large group of degenerative and metabolic disorders, the diagnostic management of which is difficult because of the enormous clinical and genetic heterogeneity. Because of several limitations, the current classification systems provide insufficient guidance for clinicians and researchers. Here, we propose a new nomenclature for the genetically confirmed recessive cerebellar ataxias according to the principles and criteria laid down by the International ...

Tópico(s): Neurological diseases and metabolism

2018 - Wiley | Movement Disorders

Artigo Acesso aberto Revisado por pares

Caroline Kelly, Malco C. Cruz-Romero, Joseph P. Kerry, Dmitri B. Papkovsky,

Five types of new solid-state oxygen sensors, four based on microporous polypropylene fabric materials and one on polyphenylene sulphide films impregnated with phosphorescent platinum(II)-benzoporphyrin dye, were tested for their stability and safety in food packaging applications. All these sensors exhibit useful optical signals (phosphorescence lifetime readout) and working characteristics and are simpler and cheaper to produce and integrate into standard packaging materials than existing commercial ...

Tópico(s): Water Quality Monitoring and Analysis

2018 - Multidisciplinary Digital Publishing Institute | Chemosensors

Artigo Revisado por pares

Joseph Christopher Hannon, Joseph P. Kerry, Malco C. Cruz-Romero, Shafrina Azlin-Hasim, Michael A. Morris, Enda Cummins,

The release of silver (Ag) from an experimental nanosilver spray coating on surface treated polyester (PT) and low density polyethylene (LDPE) packaging into milk was determined. Spherical nanoparticles (NPs) with a high electron density and crystalline face centred cubic structure characteristic of silver nanoparticles (AgNPs) were characterised in milk by cryogenic transmission electron microscopy (TEM). Total Ag migration into milk over time was determined by inductively coupled plasma – atomic emission ...

Tópico(s): Microplastics and Plastic Pollution

2018 - Elsevier BV | Food Packaging and Shelf Life

Artigo Acesso aberto Revisado por pares

Olga Moreno, Lorena Atarés, Amparo Chiralt, Malco C. Cruz-Romero, Joseph P. Kerry,

Antimicrobial starch:gelatin (1:1) films containing N-α-lauroyl-l-arginine ethyl ester monohydrochloride (LAE) (10 % wt.) were used as food contact active layers in chicken breast fillets vacuum-packaged in polyamide/polyethylene pouches. Active layers were thermoprocessed (TP) or cast (OC) on the plastic film. Oxidized starch was used in OC coatings. Packaged chicken breast samples were stored at 4 °C and their physicochemical properties (pH, colour and lipid oxidation) and microbial quality were analysed ...

Tópico(s): Antimicrobial agents and applications

2018 - Elsevier BV | LWT

Artigo Acesso aberto Revisado por pares

David Joseph Sullivan, Malco C. Cruz-Romero, Timothy W. Collins, Enda Cummins, Joseph P. Kerry, Michael A. Morris,

Tópico(s): biodegradable polymer synthesis and properties

2018 - Elsevier BV | Food Hydrocolloids

Artigo Acesso aberto

Ciara M. O’Neill, Malco C. Cruz-Romero, Geraldine Duffy, Joseph P. Kerry,

The objective of this study was to develop sensory accepted low-salt cooked ham by the application of response surface methodology (RSM). A Box-Behnken experimental design was used to assess the effects of the independent factors salt replacer (Artisalt™) (0–100%), high pressure treatment (0.1–600 MPa) and a mix of organic acids (Inbac™) (0.2–0.4%) on hardness, flavour, saltiness and overall sensory acceptability (OSA) of the cooked ham. The main factor that affected all response variables was salt replacement. ...

Tópico(s): Insect Utilization and Effects

2017 - Elsevier BV | Innovative Food Science & Emerging Technologies

Revisão Acesso aberto Revisado por pares

Michael A. Morris, Sibu C. Padmanabhan, Malco C. Cruz-Romero, Enda Cummins, Joseph P. Kerry,

Fresh and processed muscle-based foods are highly perishable food products and packaging plays a crucial role in providing containment so that the full effect of preservation can be achieved through the provision of shelf-life extension. Conventional packaging materials and systems have served the industry well, however, greater demands are being placed upon industrial packaging formats owing to the movement of muscle-based products to increasingly distant markets, as well as increased customer ...

Tópico(s): Microplastics and Plastic Pollution

2017 - Elsevier BV | Meat Science

Artigo Acesso aberto Revisado por pares

Cinthia Terroba‐Chambi, Malco Rossi, Andrea Bril, Patricio Millar Vernetti, Daniel Cerquetti, Ángel Cammarota, Marcelo Merello,

The diagnosis of Parkinson's disease (PD) can be challenging early in the disease course, when motor features are subtle. The objective of this study was to explore the diagnostic value of combining acute levodopa challenge and olfactory testing to predict PD.

Tópico(s): Conducting polymers and applications

2017 - Wiley | Movement Disorders Clinical Practice

Artigo Acesso aberto

Joseph Christopher Hannon, Joseph P. Kerry, Malco C. Cruz-Romero, Shafrina Azlin-Hasim, Michael A. Morris, Enda Cummins,

To predict the kinetic desorption of silver from an experimental nanosilver coated polystyrene food packaging material into food simulants (0, 1, 2 and 3% acetic acid (HAc) in distilled water (dH2O)) at 4 temperatures (10, 20, 40 and 70 °C), 5 sorption models were examined for their performance. A pseudo-second order kinetic sorption model was found to provide the best prediction of an unseen desorption validation dataset with R2 = 0.90 and RMSE = 3.21. Poor predictions were witnessed for desorption at 70 ° ...

Tópico(s): Recycling and Waste Management Techniques

2017 - Elsevier BV | Innovative Food Science & Emerging Technologies

Artigo Revisado por pares

Julieta Arena, Daniel Cerquetti, Malco Rossi, Hernán Chaves, Cecilia Rollán, Daiana Dossi, Marcelo Merello,

To determine whether brain white matter hyperintensities (WMH) influence l-dopa response in Parkinson's disease (PD) patients.We prospectively evaluated 60 PD patients with an acute l-dopa challenge test, and assessed motor performance with the Movement Disorders Society revised Unified Parkinson's Disease Rating Scale (MDS-UPDRS) during "ON" and "OFF" medication states. Magnetic resonance images were examined using a visual semi-quantitative rating scale for quantification and distribution analysis ...

Tópico(s): Advanced Neuroimaging Techniques and Applications

2016 - Elsevier BV | Parkinsonism & Related Disorders

Artigo Revisado por pares

Malco Rossi, Alex Medina Escobar, Andrea Bril, Patricio Millar Vernetti, Juan Ignacio De Palo, Daniel Cerquetti, Marcelo Merello,

Normosmic Parkinson's disease (PD) might be a unique clinical phenotype with a more benign course when compared with hyposmic PD.The objective of this study was to evaluate motor features and the acute levodopa response according to olfactory function.A total of 169 de novo PD patients that underwent olfactory testing and acute levodopa challenge for clinical prediction of sustained long-term dopaminergic response were evaluated.The overall frequency of normosmia was 33%. Normosmic PD patients scored ...

Tópico(s): Parkinson's Disease Mechanisms and Treatments

2016 - Wiley | Movement Disorders

Artigo Acesso aberto Revisado por pares

David J. Clarke, Andrey A. Tyuftin, Malco C. Cruz-Romero, Declan Bolton, Séamus Fanning, S.K. Pankaj, C. Bueno-Ferrer, Patrick J. Cullen, Joe P. Kerry,

Two antimicrobial coatings, namely Sodium octanoate and Auranta FV (a commercial antimicrobial composed of bioflavonoids, citric, malic, lactic, and caprylic acids) were used. These two antimicrobials were surface coated onto the inner polyethylene layer of cold plasma treated polyamide films using beef gelatin as a carrier and coating polymer. This packaging material was then used to vacuum pack beef sub-primal cuts and stored at 4 °C. A control was prepared using the non-coated commercial laminate ...

Tópico(s): Microplastics and Plastic Pollution

2016 - Elsevier BV | Food Microbiology