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Bill Price, Anthony Harris, David Adams, Iain R. Webb, DJM, Robin Butler, Anthony Clare, Simon Barnes, Roger Ely, Sarah Bagnall, Insurance Correspondent, Tim Judah, Neil Bennett, Alexandra Frean, Media Correspondent, Pierre Trudeau, Elizabeth Manners, Philip Howard, Hilary Finch, Alexandra Frean Media Correspondent, Noel Goodwin, Carl Mortished, Gareth Boote, Jenny Knight, Stewart Tendler, Crime Correspondent, Kevin Eason, Philip Russell, Gerald Davies, Joe Joseph, Michael Alison, Jeremy Laurance, Health Services Correspondent, Martin Fletcher, Michael Dynes Whitehall Correspondent, Ruth Gledhill, Religion Correspondent, Jonathan Prynn, Political Reporter, Peter Ball, Reginald Murley President, Raymond Keene Chess Correspondent, Rob Hughes Football Correspondent, Libby Purves, Donald Anderson, Alan Hamilton, John Patten, Harry Wu, Keith Pike, Jonathan Prynn Political Reporter, Charles Bremner, Brian Johnson, Ian McIntyre, Edward Gorman, Sean French, Martin Smith, Sanjay Joshi, Neil Williams, Jenny Shields and Richard Duce, Sydney Friskin, Andy Lavender, Nicholas Wood Chief Political Correspondent, John Hopkins, David Miller, Barry Millington, Arthur Leathley, Political Correspondent, Brentford, Melvyn Marckus City Editor, John Mayo, Raymond Keene, Philip Worcester, Alan Lee, Cricket Correspondent, John Russell Taylor, John Coleman Editor, Simon C. Barnes, Rachel Collins, Richard Evans, Peter Mortimore, Tim Jones Transport Correspondent, Oliver Holt, Marcel Berlins, Brian Beel, David Hands Rugby Correspondent, Julian Muscat, Martin Waller, Deputy City Editor, Christopher Thomas, William Rees-Mogg, Sara McConnell, Mel Webb, Kevin McCarra, Malcolm McKeag, Christopher Walker, Middle East Correspondent, John Shaw, A. H. Amery (Consultant surgeon), Walter Gammie, Anthony Loyd, Peter Riddell, Ben MacIntyre, Ian Brodie, Michael Coleman and Chris Moore, Tom Rhodes and Joel Brand and Michael Evans, Richard Beeston, Martin Flanagan and Philip Pangalos, Simon Jenkins, Stephen Pettitt, Benedict Nightingale, Marianne Curphey, Rob Andrew, David Powell, Sam Kiley, Jenny Braithwaite, Michael Henderson, Dan Elwyn Jones (Head of Campaigns), Michael Evans, Tim Judah on Mount Trebevic, George White, Colin Campbell, Jonathan Mirsky, Christopher Irvine,

Newish Man Serb retreat lifts threat of air strikes Russians warn against bombing as Nato's aircraft stay on full alert On Other Pages Police step up ...

1994 - Gale Group | TDA

Revisão

Mari Niemi, Juha Karjalainen, Rachel G. Liao, Benjamin M. Neale, Mark J. Daly, Andrea Ganna, Gita A. Pathak, Shea J. Andrews, Masahiro Kanai, Kumar Veerapen, Israel Fernández‐Cadenas, Eva C. Schulte, Pasquale Striano, M. Marttila, Camelia C. Minică, Eirini Marouli, Mohd Anisul Karim, Frank R. Wendt, Jeanne E. Savage, Laura Sloofman, Guillaume Butler‐Laporte, Han‐Na Kim, Stavroula Kanoni, Yukinori Okada, Jinyoung Byun, Younghun Han, Mohammed Jashim Uddin, George Davey Smith, Cristen J. Willer, Joseph D. Buxbaum, Juha Mehtonen, Hilary K. Finucane, Mattia Cordioli, Alicia R. Martin, Wei Zhou, Bogdan Paşaniuc, Hanna Julienne, Hugues Aschard, Huwenbo Shi, Loïc Yengo, Renato Polimanti, Maya Ghoussaini, Jeremy Schwartzentruber, Ian Dunham, Karolina Chwiałkowska, Margherita Francescatto, Amy Trankiem, Mary K. Balaconis, Lea K. Davis, Sulggi A. Lee, James R. Priest, Alessandra Renieri, Vijay G. Sankaran, David A. van Heel, Patrick Deelen, J. Brent Richards, Tomoko Nakanishi, Les Biesecker, V. Eric Kerchberger, J. Kenneth Baillie, Francesca Mari, Anna Bernasconi, J. Kenneth Baillie, Arif Canakoglu, Brooke N. Wolford, Annika Faucon, Atanu Kumar Dutta, Claudia Schurmann, Emi N. Harry, Ewan Birney, Huy Nguyen, Jamal Nasir, Mari Kaunisto, Matthew Solomonson, Nicole Dueker, Nirmal Vadgama, Sophie Limou, Souad Rahmouni, Hamdi Mbarek, Dima Darwish, Md Mesbah Uddin, Raquel Albertos, Jordi Pérez‐Tur, Ruolin Li, Lasse Folkersen, Ida Moltke, Nils Koelling, Alexander Teumer, Athanasios Kousathanas, Alicia Utrilla, Ricardo A. Verdugo, Ruth Zárate, Carolina Medina‐Gómez, David Gómez-Cabrero, Elena Carnero‐Montoro, Carmen L. Cadilla, Andrés Moreno‐Estrada, Adriana Garmendia, Leire Moya, Bahareh Sedaghati-khayat, Palwendé Romuald Boua, Marie-Julie Favé, Laurent C. Francioli, Audrey Lemaçon, Isabelle Migeotte, Sanjay Patel, Réka Várnai, József Szentpéteri, Csilla Sipeky, Francesca Colombo, Kathrin von Hohenstaufen, Píetro Lió, Costanza L. Vallerga, Qingbo Wang, Yosuke Tanigawa, Hogune Im, Chulho Han, Han Song, Jiwoo Lim, Y.‐A. Lee, Sugyeong Kim, Sangyoon Im, Biljana Atanasovska, Hajar Fauzan Ahmad, Cindy G. Boer, Philip R. Jansen, Lude Franke, Elżbieta Kaja, Dorota Pasko, Ingrid Kennis-Szilagyi, Sergey A. Kornilov, Vid Prijatelj, Ivana Nedeljković, Ilangkumaran Sivanadhan, Sarala Perumal, Sahar Esmaeeli, Nathaniel M. Pearson, Adam Auton, Janie F. Shelton, Anjali J. Shastri, Teresa Filshtein-Sonmez, Daniella Coker, Antony Symons, Jorge Esparza-Gordillo, Stella Aslibekyan, Jared O’Connell, Chelsea Ye, Catherine H. Weldon, Minoli A. Perera, Kevin J. O’Leary, Matthew Tuck, Travis J. O’Brien, David Meltzer, Peter H. O’Donnell, Edith A. Nutescu, Guang Yang, Cristina Alarcón, Stefanie Herrmann, Sophia Mazurek, Jeff Banagan, Zacharia Hamidi, April Barbour, Noora Raffat, Diana Moreno, Paula N. Friedman, Bart Ferwerda, Diederik van de Beek, Matthijs C. Brouwer, Alexander P. J. Vlaar, W. Joost Wiersinga, Daniëlle Posthuma, Elleke Tissink, Aeliko Zwinderman, Emil Uffelmann, Michiel A. van Agtmael, Anne Geke Algera, Frank van Baarle, Diane Bax, Martijn Beudel, Harm Jan Bogaard, Marije K. Bomers, Peter I. Bonta, Lieuwe D. J. Bos, Michela Botta, Justin de Brabander, Godelieve de Bree, Sanne de Bruin, Marianna Bugiani, Esther Bulle, Osoul Chouchane, Alex Cloherty, Dave A. Dongelmans, Paul Elbers, Lucas M. Fleuren, Suzanne E. Geerlings, Bart F. Geerts, Teunis B. H. Geijtenbeek, Armand R. J. Girbes, Abraham Goorhuis, Martin P. Grobusch, Florianne Hafkamp, Laura A. Hagens, Jörg Hamann, Vanessa Harris, Robert Hemke, Sabine Hermans, Leo Heunks, Markus W. Hollmann, Janneke Horn, Joppe W. Hovius, Menno D. de Jong, Rutger Koning, Niels van Mourik, Jeannine F. Nellen, Esther J. Nossent, Frederique Paulus, Edgar Peters, Tom van der Poll, Bennedikt Preckel, Jan M. Prins, Jorinde Raasveld, Tom D. Y. Reijnders, Michiel Schinkel, Marcus J. Schultz, Alex R. Schuurman, Kim Sigaloff, Marry R. Smit, Cornelis Stijnis, Willemke Stilma, Charlotte E. Teunissen, Patrick Thoral, Anissa M. Tsonas, Marc van der Valk, Denise P. Veelo, Heder de Vries, Michèle van Vugt, Dorien Wouters, René Minnaar, Adrie Kromhout, Kees W. J. van Uffelen, Ruud A. Wolterman, Genevieve Roberts, Daniel J. Park, Catherine A. Ball, Marie V. Coignet, Shannon McCurdy, Spencer C. Knight, Raghavendran Partha, Brooke Rhead, Miao Zhang, Nathan Berkowitz, Michael Gaddis, Keith Noto, Luong Ruiz, Miloš Pavlović, Eurie L. Hong, Kristin A. Rand, Ahna R. Girshick, Harendra Guturu, Asher Haug Baltzell, Souad Rahmouni, Julien Guntz, Y Beguin, Sara Pigazzini, Lindokuhle Nkambule, Youssef Bouysran, Adeline Busson, Xavier Peyrassol, Françoise Wilkin, Bruno Pichon, Guillaume Smits, Isabelle Vandernoot, Jean‐Christophe Goffard, Michel Georges, Michel Moutschen, Benoît Misset, Gilles Darcis, Julien Guiot, Laurent Jadot, Samira Azarzar, Patricia Dellot, Stéphanie Gofflot, Sabine Claassen, Axelle Bertrand, Gilles Parzibut, Mathilde Clarinval, Catherine Moermans, Olivier Malaise, Kamilia El Kandoussi, Raphaël Thonon, Pascale Huynen, Alyssia Mesdagh, Sofia Ferreira Melo, Nicolas Jacques, Emmanuel Di Valentin, François Giroule,

The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed ...

Nature Portfolio

Jornais Acesso aberto

Freda Pitt, C. S. Forester, J. J. R. Trethowan, Kathleen Gibberd Educational Correspondent of The Sunday Times, J. B. Slade-Baker Representative of The Sunday Times, Mr. D. A. B. Watson's Speech, Norman Crump Sunday Times City Editoe, Stephen Coulter Representative of The Sunday Times, Elizabeth Nicholas, (Miss) E. M. Bullock, Ian Peebles, James Margach Political Correspondent of The Sunday Times, J. D. Scott, Henry Thody The Sunday Times Representative, Philip Goodhart, Nicholas Carroll The Sunday Times Diplomatic Correspondent, S. S. van Dine, J. W. Lambert, Andrew Dakers, Ruth T. Clark, Ward Smith, Julian Symons, F.-M. Viscount Montgomery K. G., Myfanwy Piper, Cyril Beaumont, Joyce Emerson, C. F. Beck, John Pearson, Frances Noyes Hart, John Russell, David Barnett The Sunday Times Representative, Barbara Evans, Elizabeth David, R. J. C. Atkinson, Vivian Jenkins, Gordon Bates, Penelope Mortimer, G. R. M. Garratt Deputy Keeper, Theo. A. Stephens, lain Lang, Alan Moorehead, Antony Terry The Sunday Times Representative, Thelda Tranfield, Stella Frank, Cyril Connolly, Baroness Orczy, Aleo Lermon, Henry Brandon The Sunday Times Representative, Richard Hughes Representative of The Sunday Times, Stanley G. Fisher, Raymond Mortimer, Field-Marshal Viscount Montgomery K. G., E. Colston Shepherd Air Correspondent of The Sunday Times, Robert Blake, Agatha Christie, G. K. Chesterlon, Violet Wyndham, Glyn Daniel The Sunday Times Archaeological Correspondent, William Robson-Brown, J. P. Pickering, Mr. M. W. H. Bolus, Maurice Leblanc, A. A. Milne, Philip Wills Chairman of the British Gliding Association, Edger Wallace, J. H. Plumb, Henry Brandon Representative of The Sunday Times, R. M. Jones Deputy Matron, Roger Mortimer, Kathleen M. St. P. Crump Former Chairman, James Wilson, Antony Terry Representative of The Sunday Times, John Raymond, S. W. Roskill, Peter Collins Science Correspondent of The Sunday Times, Desmond Shawe-Taylor, Ernest G. Kleinwort, Arthur Morley The Sunday Times Representative, David Drew, Bernard Hollowood Editor of "Punch", J. H. de W. Waller, Bernard Malone, Hilary Seton, R. L. Hollands, Dilys Powell, Charles Madge, Robert Williamson Press. Officer, Freeman Wills Crofts, Joseph Mostyn The Sunday Times Representative, Richard Hughes The Sunday Times Representative, A. E. W. Mason, Felix Aprahamian, Sidney Rogerson, Maurice Cranston, Jack Fingleton, Stephen Coulter The Sunday Times Representative, H. H. Houghton, Robert Robinson, Henry Longhurst, S. Knox Cunningham, Miss U. S. Parker, John E. Clouting, Stirling Moss, P. D., Joe O'Gorman, R. Austin Freeman, E. C. Bentley, Earl Attlee, S. St. Clair Morrison, C. H. O'd. Alexander, George Schwartz, Maurice Wiggin, Atticus, Felix Aylmer, Sir Thomas Moore, Doris Langley Moore, Ernest Bramah, Robert Harling, Stephen Potter, A. J. Brayshaw General Secretary, Gaston Leroux, G. de la Condamine, Gordon Ross, The Rev. G. W. Butterworth Litt. D., Ella King (Manageress N. A. A. F. L.), M. M. Melinsky, Kenneth Konstam, Siriol Hugh-Jones, W. A. Hewltson, Baroness Wootton,

... Yesterday's Football Results, Scorers, and League Tables Mortimore Off to Join M. C. C The Scoreboard ...

1958 - Gale Group | Sunday Times HA GDA

Artigo

Felicity Liew, Shubha Talwar, Andy Cross, Brian J. Willett, Sam Scott, Nicola Logan, Matthew K. Siggins, Dawid Swieboda, Jasmin Sidhu, Claudia Efstathiou, Shona C. Moore, Christopher Davis, Noura Mohamed, J Nunag, Clara King, A. A. Roger Thompson, Sarah Rowland‐Jones, Annemarie B Docherty, James D. Chalmers, Ling‐Pei Ho, Alex Horsley, Betty Raman, Krisnah Poinasamy, Michael Marks, Onn Min Kon, Luke Howard, Dan Wootton, Susanna Dunachie, Jennifer K Quint, Rachael A. Evans, Louise V. Wain, Sara Fontanella, Thushan I. de Silva, Antonia Ho, Ewen M. Harrison, J. Kenneth Baillie, Malcolm G. Semple, Christopher E. Brightling, Ryan S. Thwaites, Lance Turtle, Peter Openshaw, J. Kenneth Baillie, Peter Openshaw, Malcolm G. Semple, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, Kanta Chechi, G Cooke, Ana da Silva Filipe, Thushan I. de Silva, Annemarie B Docherty, Gonçalo dos Santos Correia, Marc‐Emmanuel Dumas, Jake Dunning, Tom Fletcher, Christopher Green, William Greenhalf, Julian L. Griffin, Rishi K. Gupta, Ewen M. Harrison, Antonia Ho, Karl Holden, Peter Horby, Samreen Ijaz, Say Khoo, Paul Klenerman, Andrew Law, Matthew C. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Shona C. Moore, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L. Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, Caroline Sands, J. T. Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Olivia Swann, Zoltán Takáts, Panteleimon G. Takis, Richard S. Tedder, A. A. Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Lisa Norman, Riinu Pius, Catherine A. Shaw, Marie Connor, Jo Ann Dalton, Carrol Gamble, Michelle Girvan, Sophie Halpin, Ewen M. Harrison, Clare Jackson, James Lee, Laura Marsh, Daniel Plotkin, Stephanie Roberts, Egle Saviciute, Sara Clohisey, Ross Hendry, Susan Knight, Eva Lahnsteiner, Andrew Law, Gary Leeming, Lucy Norris, James Scott-Brown, Sarah Tait, Murray Wham, Richard Clark, Audrey Coutts, Lorna Donelly, Angie Fawkes, Tammy Gilchrist, Katarzyna Hafezi, Louise MacGillivray, Alan Maclean, Sarah McCafferty, Kirstie Morrice, Lee Murphy, Nicola Wrobel, Gail Carson, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Colin Berry, Nicola Best, Pieter Bothma, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Tassos Grammatikopoulos, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Joanne Howard, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Thapas Nagarajan, Megan Nagel, Mark Nelson, Lillian Norris, Matthew K. O’Shea, Marlies Ostermann, Igor Otahal, Mark Pais, Carlo Palmieri, Selva Panchatsharam, Danai Papakonstantinou, Padmasayee Papineni, Hassan Paraiso, Brij Patel, Natalie Pattison, Justin Pepperell, Mark Peters, Mandeep Phull, Stefania Pintus, Tim Planche, Frank A. Post, David Price, Rachel Prout, Nikolas Rae, Henrik Reschreiter, Tim Reynolds, Neil Richardson, Mark Roberts, Devender Roberts, Alistair Rose, Guy Rousseau, Bobby Ruge, Brendan Ryan,

Background Most studies of immunity to SARS-CoV-2 focus on circulating antibody, giving limited insights into mucosal defences that prevent viral replication and onward transmission.We studied nasal and plasma antibody responses one year after hospitalisation for COVID-19, including a period when SARS-CoV-2 vaccination was introduced.Methods In this follow up study, plasma and nasosorption samples were prospectively collected from 446 adults hospitalised for COVID-19 between February 2020 and March ...

Elsevier BV

Jornais Acesso aberto

From Our Racing Correspondent, FROM OUR ATHLETICS CORRESPONDENT, From Our Cricket Correspondent, From a Staff Reporter, FROM OUR ASSOCIATION FOOTBALL CORRESPONDENT, FROM OUR BOXING CORRESPONDENT, FROM OUR CORRESPONDENT, From Our Labour Correspondent, From Our Industrial Correspondent, FROM OUR SPECIAL CORRESPONDENT, From a Medical Correspondent, From Our Scottish Correspondent-GLASGOW, JUNE 3, FROM OUR LABOUR STAFF, From Our Political Correspondent, FROM OUR MIDLAND CORRESPONDENT, FROM OUR POLITICAL CORRESPONDENT, FROM OUR SHIPPING CORRESPONDENT, From Our Special Correspondent-SWINDON, JUNE 3, FROM OUR EQUESTRIAN CORRESPONDENT, From a Special Correspondent-SAIGON, FROM A SPECIAL CORRESPONDENT, FROM OUR UNITED NATIONS CORRESPONDENT, FROM OUR OWN CORRESPONDENT, From Our Own Correspondent-WASHINGTON, JUNE 3, From Our Own Correspondent-BONN, FROM OUR COMMONWEALTH STAFF, From Our Correspondent-ANKARA, From Our Own Correspondent, FROM OUR LATIN AMERICA CORRESPONDENT, From Our Correspondent, From Our Parliamentary Correspondent-WESTMINSTER, WEDS., From Our Commonwealth Staff, From Our Special Correspondent-ABERDEEN, JUNE 3, JOHN LAWRIE., WM. S. MITCHELL, Librarian. The University of Newcastle upon Tyne., DIANA STEPHENS., T. C. HAYWARD, Clerk of the Peace, DAVID NAPLEY., P. C. BULLOCK, General Secretary., RITA HINDEN., From Our Africa Correspondent, who has recently visited Ivory Coast. Mali, Senegal, and Guinea., C. J. C. McOUSTRA., MICHAEL ROBERTS., P. M. BOWEN, FROM OUR PHILATELIC CORRESPONDENT, FROM OUR AERONAUTICAL CORRESPONDENT, FROM OUR SALE ROOM CORRESPONDENT, FROM A CORRESPONDENT, FROM OUR ESTATES CORRESPONDENT, By Oliver Edwards, From Our Dramatic Critic-STRATFORD-ON-AVON, JUNE 3, FROM OUR MUSIC CRITIC, From Our Film Critic, From Our Special Correspondent-WIESBADEN, By Our City Editor, From a Correspondent, FROM LLOYD'S,

... Khrushchev Visit Oslo Fear Of Clashes, Roehampton Croquet, Mortimore Alone Resists Kent Towering Gravesend Sixes, Santa Claus ... Finance: J. & P. Coats, Patons & Baldwins Limited Sir Malcolm McDougall's Review, Mount Charlotte In Holborn Deal, ...

1964 - Gale Group | TDA

Artigo

Benedict Michael, Cordelia Dunai, Edward Needham, Kukatharmini Tharmaratnam, Robyn Williams, Yun Huang, Sarah Boardman, Jordan J. Clark, Parul Sharma, Krishanthi Subramaniam, Greta K. Wood, Ceryce Collie, Richard Digby, Alexander Ren, Emma Norton, Maya Leibowitz, Soraya Ebrahimi, Andrew Fower, Hannah Fox, Esteban Tato, Mark Ellul, Geraint Sunderland, Marie Held, Claire Hetherington, Franklyn Egbe, Alish B. Palmos, Kathy Stirrups, Alexander Grundmann, Anne-Cécile Chiollaz, Jean-Charles Sánchez, James P. Stewart, Michael J. Griffiths, Tom Solomon, Gerome Breen, Alasdair Coles, Nathalie Kingston, John R. Bradley, Patrick F. Chinnery, Jonathan Cavanagh, Sarosh R. Irani, Angela Vincent, J. Kenneth Baillie, Peter Openshaw, Malcolm G. Semple, J. Kenneth Baillie, Peter Openshaw, Malcolm G. Semple, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, Kanta Chechi, G Cooke, Ana da Silva, Thushan I. de Silva, Annemarie B Docherty, Gonçalo dos Santos, Marc‐Emmanuel Dumas, Jake Dunning, Tom Fletcher, Chris Green, William Greenhalf, Julian L. Griffin, Rishi K. Gupta, Ewen M. Harrison, A. Wai, Karl Holden, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Matthew R. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Alexander J. Mentzer, Laura Merson, Alison Meynert, Shona C. Moore, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L. Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, Caroline Sands, J. T. Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Olivia Swann, Zoltán Takáts, Panteleimon G. Takis, Richard S. Tedder, A. A. Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Lisa Norman, Riinu Pius, Catherine A. Shaw, Marie Connor, Jo Ann Dalton, Carrol Gamble, Michelle Girvan, Sophie Halpin, Ewen M. Harrison, Clare Jackson, James Lee, Laura Marsh, Daniel Plotkin, Stephanie Roberts, Egle Saviciute, Sara Clohisey, Ross Hendry, Susan Knight, Eva Lahnsteiner, Gary Leeming, Lucy Norris, James Scott-Brown, Sarah Tait, Murray Wham, Richard E. Clark, Audrey Coutts, Lorna Donnelly, Angie Fawkes, Tammy Gilchrist, Katarzyna Hafezi, Louise MacGillivray, Alan Maclean, Sarah McCafferty, Kirstie Morrice, Lee Murphy, Nicola Wrobel, Gail Carson, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Colin Berry, Nicola Best, Pieter Bothma, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Tassos Grammatikopoulos, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Joanne Howard, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Enock Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig F. Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Thapas Nagarajan, Megan Nagel, Mark Nelson, Lillian Norris, Matthew K. O’Shea, Marlies Ostermann, Igor Otahal, Mark Pais, Selva Panchatsharam, Danai Papakonstantinou, Padmasayee Papineni, Hassan Paraiso, Brij Patel, Natalie Pattison, Justin Pepperell, Mark Peters, Mandeep Phull, Stefania Pintus, Tim Planche, Frank A. Post, Ashley Price, Rachel Prout, Nikolas Rae, Henrik Reschreiter, Tim Reynolds, Neil Richardson, Mark Roberts, Devender Roberts, Alistair Rose, Guy Rousseau, Bobby Ruge, Brendan Ryan, Taranprit Saluja,

To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and autoantibodies in 203 hospitalised participants; 111 with acute sera (1-11 days post-admission) and 92 convalescent sera (56 with COVID-19-associated neurological diagnoses). Here we show that compared to 60 uninfected controls, tTau, GFAP, NfL, and UCH-L1 are increased with COVID-19 infection at acute timepoints and NfL and GFAP are significantly ...

Nature Portfolio

Artigo

Michael Sullivan, Jennifer S. Lees, Thomas M Drake, Annemarie B Docherty, Georgia Oates, Hayley E Hardwick, Clark D Russell, Laura Merson, Jake Dunning, Jonathan S. Nguyen‐Van‐Tam, Peter Openshaw, Ewen M. Harrison, J. Kenneth Baillie, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Chris Green, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, A. A. Roger Thompson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Thomas M Drake, Cameron J. Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sara McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, William Greenhalf, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J Eunice Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Kirstie Morrice, Alan Maclean, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul B. Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Megan Nagel, Thapas Nagarajan, Mark E. Nelson, Matthew K. O’Shea, Igor Otahal, Marlies Ostermann, Mark Pais, Selva Panchatsharam, Danai Papakonstantinou,

Acute kidney injury (AKI) is common in coronavirus disease 2019 (COVID-19). This study investigated adults hospitalized with COVID-19 and hypothesized that risk factors for AKI would include comorbidities and non-White race.

Oxford University Press

Jornais Acesso aberto

From Our Cricket Correspondent, From Our Racing Correspondent, FROM OUR RACING CORRESPONDENT, FROM OUR NEWMARKET CORRESPONDENT, From Our Yachting Correspondent, FROM OUR BURNHAM CORRESPONDENT, FROM OUR SCOTTISH CORRESPONDENT, FROM OUR CORRESPONDENT, BY OUR MEDICAL CORRESPONDENT, FROM OUR MOTORING CORRESPONDENT, FROM OUR SCIENCE CORRESPONDENT, FROM OUR LABOUR CORRESPONDENT, From Our Own Correspondents, FROM OUR SPECIAL CORRESPONDENT, From Our Correspondent, From Our Own Correspondent, Our Diplomatic Correspondent, FROM OUR OWN CORRESPONDENT, FROM OUR MIDDLE EAST CORRESPONDENT, FROM OUR COMMONWEALTH STAFF, FROM OUR CITY EDITOR, From Our Labour Correspondent, From Our Science Correspondent, JOHN H. EVERNDEN., HARRY SAMUELS, C. D. NORTH-LEWIS., R. J. ISAAC., J. D. JONES, MERLIN MINSHALL, H. A. VERNEY., S. C. DESCH., CECIL GILLINGTON., GEOFFREY WILSON, JOHN MAVROGORDATO., ROGER CALVERT., By Tom Little, PHILIP HANCOCK., Mr. Emanuel Shinwell, FROM A CORRESPONDENT, FROM OUR MUSIC CRITIC, From Our Aeronautical Correspondent, FROM OUR FILM CRITIC, By Our City Editor, FROM A PARIS CORRESPONDENT, FROM A CORESPONDENT, FROM OUR INSURANCE CORRESPONDENT, By Dr. C. V. GOCKING, By The Hon. A. N. R. ROBINSON, By Our Special Correspondent, By Sir EDWARD BEETHAM, By L. E. S. BRAITHWAITE, By Sir LEARIE CONSTANTINE, By St. G. C. COOPER, By a Special Correspondent, By CYRIL MERRY, From The Times AERONAUTICAL CORRESPONDENT, By Marshal of the R.A.F. SIR JOHN SLESSOR, By JAMES MARTIN, By W. S. LITTLE, By K. G. DOBSON, By JAMES HAY STEVENS, By A Special Correspondent, By Air Commodore SIR FRANK WHITTLE, By Dr. K. G. BERGIN, By A. V. CLEAVER, By Dr. S. G. HOOKER and A. V. N. REED, By D. M. DESOUTTER, By E. COLSTON SHEPHERD, By R. J. WALDEN, By SIR GRAHAM SUTTON, By CLIVE ADAMS, A. J. BURKART, From Our Radio Correspondent, By J. D. PEARSON, By F. FOX, By A. HOLT, By MALCOLM POWLEY of Ferranti, By Wing Commander NORMAN MACMILLAN, By ROBERT BLACKBURN, By N. G. BENNETT, By JOHN FRICKER, By Dr. A. E. SLATER,

... Pakistan Held To A Draw, Breezy Batting By Mortimore, First Winner For 18 Months, Payne To Captain ...

1962 - Gale Group | TDA

Artigo

Clark D Russell, Cameron J Fairfield, Thomas M Drake, Lance Turtle, R Andrew Seaton, Dan Wootton, Louise Sigfrid, Ewen M. Harrison, Annemarie B Docherty, Thushan I. de Silva, Conor Egan, Riinu Pius, Hayley E Hardwick, Laura Merson, Michelle Girvan, Jake Dunning, Jonathan S. Nguyen‐Van‐Tam, Peter Openshaw, J. Kenneth Baillie, Malcolm G. Semple, Antonia Ho, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Ewen M. Harrison, Julian A. Hiscox, Antonia YW Ho, Peter Horby, Samreen Ijaz, Say Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, AA Roger Thompson, Ryan S. Thwaites, Lance Turtle, Rishi K. Gupta, Carlo Palmieri, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sarah E. McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, William Greenhalf, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah E. McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Jihui Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Kirstie Morrice, Alan Maclean, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla,

Microbiological characterisation of co-infections and secondary infections in patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe microbiologically confirmed co-infections and secondary infections, and antimicrobial use, in patients admitted to hospital with COVID-19.The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) WHO Clinical Characterisation Protocol UK (CCP-UK) study is an ongoing, prospective cohort study recruiting inpatients ...

Elsevier BV

Jornais Acesso aberto

From MICHAEL KNIPE, From PAUL MARTIN, By OUR DIPLOMATIC STAFF, From Our Labour Correspondent, BY OUR POLITICAL STAFF, By ALEX HENDRY, By NORMAN FOWLER, Home Affairs Correspondent, BY A STAFF REPORTER, By Our Broadcasting Correspondent, From JULIAN MOUNTER, From TIM JONES, By a Staff Reporter, Our Local Government Correspondent writes: To preserve the, From Our Own Correspondent, FROM OUR SCOTTISH CORRESPONDENT, By ARTHUR REED, Air Correspondent, FROM A SPECIAL CORRESPONDENT, Pearce Wright, By CHARLES DOUGLAS-HOME, Defence Correspondent, By Our Legal Correspondent, FROM OUR OWN CORRESPONDENT, From Our Correspondent, From Our correspondent, From LOUIS HEREN, From DAVID SPANIER, FROM OUR CORRESPONDENT, From GEOFFREY SUMNER, By Our Foreign Staff, From CHARLES HARGROVE, By Michael Billington, From Joan Chissell, By John Percival, M.B., By Alan Blyth, By Guy Brett Art critic, by Valerie Grosvenor-Myer, By Nature-Times News Service, From a Correspondent, Bethia Lindars, From ERIC WIGHAM, ROY LEWIS, PHS, BERNARD FERGUSSON., A. I. SHENKMAN., EDWARD WALKER., HUGH FRASER., CHARLES LEFEAUX, A. W. SAGMAN., H. W. KITSON, ANDREW BEVERIDGE, STRETTON LICHFIELD, JOHN ARBUTHNOT, MALCOLM MUGGERIDGE., By Cameron Hazlehurst, PAUL B. ROSE, JOSEPH KELLY, BRETT CLOUTMAN., By Our Churches Correspondent, By RONALD FAUX, Yachting Correspondent, H.J.S., By NEIL ALLEN, Athletics Correspondent, From REX BELLAMY, Tennis Correspondent, By JOHN BALLANTINE, By JOHN WOODCOCK, Cricket Correspondent, By RICHARD STREETON, By ALAN GIBSON, By GEOFFREY GREEN, Football Correspondent, By SYDNEY FRISKIN, By BARRY DAVIES, By JIM SNOW, Northern Racing Correspondent, By our Northen Correspondent, By our Newmarket Correspondent, By MICHAEL PHILLIPS, Racing Correspondent, BY STUART MARSHALL, By CLIFFORD WEBB Midland Industrial Correspondent, By DENNIS DWYER, By MICHAEL BAILY, Shipping Correspondent, By GILES SMITH, By HUGH STEPHENSON, Economics Correspondent, By DAVID JONES, PATRICIA TISDALL, DAVID MILLHAM, BY THE FINANCIAL EDITOR, By ANTHONY ROWLEY, ROGER CALVERT, by Pamela Buonaventura, by Maureen S. Hardcastle, by F. J. Paley, by Peter Mytton-Davies, by Bernard Friend, by S. J. Carroll, by J. S. McGregor, by F. H. Happold, by F. N. Leisinger, by W. V. Waldron, W. H. Paul,

... And Exeter, Piggott and Lewis in amusing tussle, Mortimore master, Athletics Holden not included, Offer to Cox ...

1969 - Gale Group | TDA

Artigo

Quentin J. Leclerc, Naomi M. Fuller, Ruth H. Keogh, Karla Díaz-Ordaz, Richard Sekula, Malcolm G. Semple, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, A. A. Roger Thompson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Tom Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, James Lee, Daniel Plotkin, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Claire Petersen, Scott Mullaney, Gary Leeming, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sarah E. McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, Philip Gunning, Catherine Hartley, Antonia Ho, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah E. McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J. Eunice Zhang, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, D. Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Brealey, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary L. Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Megan Nagel, Thapas Nagarajan, Mark Nelson, Igor Otahal, Mark Pais, Selva Panchatsharam, Hassan Paraiso, Brij Patel, Natalie Pattison, Justin Pepperell, Mark Peters, Mandeep Phull, Stefania Pintus, Jagtur Singh Pooni, Frank A. Post, Ashley Price, Rachel Prout, Nikolas Rae, Henrik Reschreiter, Tim Reynolds, Neil Richardson, Mark Roberts, Devender Roberts, Alistair Rose, Guy Rousseau, Brendan Ryan, Taranprit Saluja, Aarti Shah, Prad Shanmuga,

Abstract Background Predicting bed occupancy for hospitalised patients with COVID-19 requires understanding of length of stay (LoS) in particular bed types. LoS can vary depending on the patient’s “bed pathway” - the sequence of transfers of individual patients between bed types during a hospital stay. In this study, we characterise these pathways, and their impact on predicted hospital bed occupancy. Methods We obtained data from University College Hospital (UCH) and the ISARIC4C COVID-19 Clinical Information ...

BioMed Central

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Tara Palmer-Tomkinson's, Margaret Rand, Waldemar Januszczak, John Dugdale, Hilary Mantel, Michael Prescott, Stephen Brook, Iain Morrison, Barbara Hall, Judith O'Reilly Education Correspondent, Katherine Burke, Jonathan Goodall, Donald MacGillivray, Bel Mooney, Ian Gibson, Andrew Warshaw, Philip Norman, Nicholas Rufford, Dan Pearson, Simon Patterson, John Peter, Pam Barrett, Emma Moore, Hugh McLlavanney, Sophie Dahl, L M, Richard Overy, Alma Mahler, Vera Brittain's, Alicia Wyllie Deputy Money Editor, Donna Leon, G W, John Jay, Frank Whitford, Susan d'Arcy Editor, T Gwillym, Charlotte Greig, Ferdinand Mount, Alistair Scott, Addison de Witt, Claus von Bulow, David Smith, Sarah Jane Marshall, Melanie Phillips, Nick Pitt, Frederic Raphael, Neil Wormald, Lord Rotherwick, Andrew Sullivan, Clive Davis, Stephen Grey, Henry Stern, Mary Wilson, Martin Kebbell, S Elias, Edward Henderson, K R, Dylan Jones, Brian Souter, Pierre Bonelli, Mark Lawrence, Justin Williams, Tony Allen-Mills, Martin James, Tom Shone Elizabeth, Anthony Sattin, Eleanor Mills, Robert Winnett, Steve Shirley's, Irwin Stelzer, Peter Wilson, Roger Anderson, Charlotte Wolff, David Dougill, Huw Davies, James Bryce Smith, Philip Kerr, Paul Gittins, Thrasy Petropoulos, Damon Hill, Terry Gilbert (Opera Attic), Marian Martin, David Hewson, Reg Williamson, Tania Alexander, Harvey Porlock, Margaret Coles, Hugh Canning, Margarette Driscoll, David Caims, Rupert Steiner Editor, John Sutherland, Jeremy Clarkson, Stewart Lee, Marina Warner, Edward Porter, Alan Brownjohn, Louise Taylor, John Waples Deputy City Editor, Diana Rigg, Jenny Shields, Robert Harris, Gabrielle Lord, Adam Coffer, Nick Caln, Frank Kermode, Cathy Scott-Clark, Kevin Connolly, Graham Otway, Hugh McManners Defence Correspondent, Nick Gardner, John Inverdale Sports Broadcaster, Terry O'Neill, Tom Reid, Lord Falconer, Paul Ham, Stuart Wavell, Josephine Smit, Malcolm Bradbury's, A McGuire, Paul Donovan, Gustav Klimt, Sue Lawrence, Philip Craigie, Simon Mills, Zoë Heller, Richard Reid, Chris Woodhead, Paul Driver, Boris Schapiro, Michael Woodhead, James Bond, Ann McFerran, Maeve Sheehan, Nicholas Hellen, Peter Windsor, Caroline Scott, O Everett, Colin Dexter, Uzi Mahnalmi, Christopher Morgan, Liz Jensen, Dr Tom Parry, Professor Peter Mortimore Director, Dave Hannigan, Michael Prescott Chief Political Correspondent, Steve Farrar Science Correspondent, Kirstie Hamilton, Alicia Wyllie, Tom Shone, Mark Edwards, Fiona McHugh, David Lawrenson, Nicholas Rufford Home Affairs Editor, Michael White, Brian Beasley, Peter Watts Editor, Robert Ayling, Anne Curtis, Lois Rogers, Nick Peters, Jennifer Asiama, Sue Reid, Raymond Keene, Hywel Thomas, Lindsay Duguid, Andrew Roberts, Marie Colvin, Sir William Purves, Hugh McLlavanay, Diana Wright, Charmian Evans, Greg Hadfield, David Orr, Chris Partridge, Helen Hawkins, Stephen Jones, Paul Nuki Consumer Affairs Editor, Nick Cain, Peta Bee, Natalie Graham, Andrew Smith, Tom Stevenson, Susan Howatch, Martin Searby, Keith Wheatley, Claire Oldfield, Mike Phillips, David Walsh, Hephzibah Anderson, Trevor Lewis, Jack Grimston, Colin McDowell, Susan Redstone, Bryan Appleyard, Hugh Johnson, Shelley Strunckel, Josh Salzmann, Mark Prigg, R W Johnson, Sheryl Garratt, Richard Woods, Garth Alexander, Ruth Rendell, Maurice Chittenden, Alex Fortune, John Foster, Kevin Pratt, Jone Hardy, Andrew Lorenz Business Editor, J Freeman, Judith O'Reilly, Ray Hutton, Jonathan Powell, Jon Ungoed-Thomas, Peter Watts, Judith Cook, Muriel Ingram, Michael Sheridan, Peter Clarke, Matthew Lynn, Donald McRae, Michael Austin, Godfrey Smith, Colin Clark, Michael Hodges, Mandy Payne, John Waples, Helen Pridham, A A Gill, Matthew Campbell, Brian Glanville, Frances Lass, David Hutcheon, Cherry Norton Social Affairs Correspondent, David Sumner Smith, Kevin Lomax, David McAlmont, Robert Johnston, Stephen Pettitt, Jonathan Carr-Brown, Trushar Barot, Cherry Norton, Malcolm Lalor, John Spurling, Sally Kinnes, Sean O'brien, Naomi Caine, Adrian Levy, David Wickers, James Mortimer, Michael Caine, Roger Dobson, Peter Smith, Mark Hodson, Nicholas Hellen Media Correspondent, J Denby, Joe Lovejoy, Christopher Higgins, Rupert Steiner, Geoffrey, Hugh Pearman, David Parsley, John Phillips, Phillip Knightley, Andrew Lorenz editor, John Burns, David Smith Economics Editor, J R, Hugh Bradley, Simon Crerar, Anthony Howard, Philip Kingsley The leading trichologist, Linda McCartney, Thomas Stuttaford, Carey Scott, Peter Sargent, Stephen Boyd, Joanna Simon, Chris Feetenby, Kingston Smith, Simon Howard, Barry Newcombe, Dominic Rushe, Lucy Rollin, Georgina Howell, Adam Parsons,

... optimism Inside the City Contents Marriott Forth Man Malcolm Bradbury's father had a love affair with ...

1998 - Gale Group | Sunday Times HA GDA

Artigo

Ryan S. Thwaites, Ashley Sanchez Sevilla Uruchurtu, Matthew K. Siggins, Felicity Liew, Clark D Russell, Shona C. Moore, Cameron J. Fairfield, Edwin Carter, Simon T. Abrams, Charlotte-Eve Short, Thilipan Thaventhiran, Emma Bergstrom, Zoe Gardener, Stephanie Ascough, Christopher Chiu, Annemarie B Docherty, David Hunt, Yanick J. Crow, Tom Solomon, Graham P. Taylor, Lance Turtle, Ewen M. Harrison, Jake Dunning, Malcolm G. Semple, J. Kenneth Baillie, Peter Openshaw, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Rishi K. Gupta, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, Roger Thompson AA, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Tom Drake, Cameron J. Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sarah McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Nicola Carlucci, Emily Cass, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Alejandra Doce Carracedo, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Lisa Flaherty, Terry Foster, Isabel García-Dorival, Willliam Greenhalf, Philip Gunning, Catherine Hartley, Anthony Holmes, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Alan Maclean, Hannah Massey, Nicole Maziere, Maria Vittoria Mancini, Sarah McCafferty, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, Kirstie Morrice, E. Gordon Murphy, Lee Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Nicola Wrobel, Jihui Zhang, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Brealey, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Sarah Cole, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anita Holme, Anil Hormis, Michael E. Jacobs, Susan Jain, Paul B. Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Enock Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore,

While it is now widely accepted that host inflammatory responses contribute to lung injury, the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from other viral lung diseases remain poorly characterized. We analyzed plasma samples from 471 hospitalized patients recruited through the prospective multicenter ISARIC4C study and 39 outpatients with mild disease, enabling extensive characterization of responses across a full spectrum of COVID-19 severity. Progressive elevation ...

American Association for the Advancement of Science

Jornais Acesso aberto

Alan Owens, St Thomas's, J. J. R. Trethowan, Richard Buckle, James Margach, James Laver, Elizabeth Nicholas, Nicholas Carroll Diplomatic Correspondent, Christopher Kavanagh, Harold Hobson, Michael Manning, Theo Goldrey, P. G. Suarez, Elizabeth Young, C. Douglas Woodward Public Relations Officer, Gordon Young, Antony Terry, Gavin Lyall, G. J. T. Parr, William Political and Economic Editor of the Sunday Times, James Fisher, Moira Keenan, J. G. Bullocke, Julian Symons, Andrew Pennycook, Anthony Lejeune, Elizabeth Good, Rosemary Manning, Henry Brandon, J. B. Priestley, John Russell, Jack Cox, David Divine, Max Marquis, Hugh Wynn, Amabel Williams-Ellis, W. C. Mortimore, F. G. Benson, Vivian Jenkins, Lionel Lumb, Arthur Morley, James Stuart, Peter Willett, M. M. Davys, F. A., Robin Marlar, Cyril Connolly, A. J. Fink, Raymond Mortimer, Marvin Kalb, Ivan Sharpe, Maxwell Boyd, John Piper, G. B. Stern, Olivia Manning, Dan Budnik, Audrey Powell, Alexander Solzhenitsyn, Oscar Turnill, Peter Wilsher, Roger Mortimer, E. A. G. Redl, Ronald Hingley, John Raymond, R. H., Ernestine Carter, Mary Clarke, Rev Cecil Northcott, Desmond Shawe-Taylor, Stephen Coulter, Gerald Osborne, David Drew, R. C. Robertson-Glasgow, Lanning Roper, Dilys Powell, Dick Taverne, Brigid Keenan, Gerald Pawle, David Wiggins, Harold Abrahams, Felix Aprahamian, Robert Carrier, Tom Stacey, Jack Fingleton, Ian Coulter Industrial Correspondent, Henry Longhurst, Colin MacInnes, Brian Glanville, St. Vincent Troubridge, Iain Lang, Richard Cox, Contango, Nicola Jane Williams, C. H. O'd. Alexander, C. R. Pyle, Maurice Wiggin, Atticus, J. M. Beattic, Collin Smith, O. M., H. J. Deverson, Storm Jameson, Frederick Browne, G. Hardy, Kenneth Konstam, Hugh Trevor-Roper,

... Byron the man Lord Byron's Wife. By Malcolm Elwin. (Macdonald. 45s.) A Prince of Holland H. ...

1962 - Gale Group | Sunday Times HA GDA

Artigo

Thomas M Drake, Aya Riad, Cameron J Fairfield, Conor Egan, Stephen R Knight, Riinu Pius, Hayley E Hardwick, Lisa Norman, Catherine A Shaw, Kenneth A McLean, A A Roger Thompson, Antonia Ho, Olivia V Swann, Michael Sullivan, Felipe Soares, Karl Holden, Laura Merson, Daniel Plotkin, Louise Sigfrid, Thushan I de Silva, Michelle Girvan, Clare Jackson, Clark D Russell, Jake Dunning, Tom Solomon, Gail Carson, Piero Olliaro, Jonathan S. Nguyen‐Van‐Tam, Lance Turtle, Annemarie B Docherty, Peter Openshaw, J Kenneth Baillie, Ewen M Harrison, Malcolm G Semple, J Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Ewen M Harrison, Julian A. Hiscox, Antonia YW Ho, Peter W Horby, Samreen Ijaz, Say Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L Robertson, Clark D Russell, Vanessa Sancho-Shimizu, J T Scott, Thushan de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David Stuart, Charlotte Summers, Richard S Tedder, Emma C. Thomson, AA Roger Thompson, Ryan S. Thwaites, Lance Turtle, Rishi K. Gupta, Carlo Palmieri, Olivia V Swann, Maria Zambon, Marc‐Emmanuel Dumas, Julian L. Griffin, Zoltan Takats, Kanta Chechi, Petros Andrikopoulos, Anthonia Osagie, Michael Olanipekun, Sonia Liggi, Matthew R. Lewis, Gonçalo dos Santos Correia, Caroline Sands, Panteleimon G. Takis, Lynn Maslen, Hayley Hardwick, Chloe Donohue, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Daniel Plotkin, James Lee, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sarah E McDonald, Seán Keating, Katie A. Ahmed, Jane A Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan J. Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, William Greenhalf, Philip J. Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, Ellen G Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Jihui Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Kirstie Morrice, Alan MacLean, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John Berridge, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul B. Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha,

BackgroundCOVID-19 is a multisystem disease and patients who survive might have in-hospital complications. These complications are likely to have important short-term and long-term consequences for patients, health-care utilisation, health-care system preparedness, and society amidst the ongoing COVID-19 pandemic. Our aim was to characterise the extent and effect of COVID-19 complications, particularly in those who survive, using the International Severe Acute Respiratory and Emerging Infections ...

Elsevier BV

Jornais Acesso aberto

By HUGH NOYES, By DAVID WOOD, Julian Mounter, By Our Business News Staff, From PETER STRAFFORD, By ARTHUR REED, BY CHRIS DUNKLEY, By Our Political Editor, A Staff Reporter, By Our Political Staff, By CLIVE BORRELL, By A Staff Reporter, By RITA MARSHALL, From JOHN CHARTRES, From Our Correspondent, By PAT HEALY, By Our Churches Correspondent, FROM OUR CORRESPONDENT, BY OUR CHURCHES CORRESPONDENT, By FRANK ROBERTS, By JOHN ROPER, BY A STAFF REPORTER, From ROGER BERTHOUD, From EDWARD MORTIMORE, From Our Own Correspondent, From CHARLES HARGROVE, FROM DAVID BONAVIA, Our Diplomatic Correspondent, Our Washington Correspondent, FROM OUR OWN CORRESPONDENT, From BERNARD GWERTZMAN, From MOSHE BRILLIANT, From IAN McDONALD, From FRED EMERY, From RICHARD WIGG, FROM PETER HAZELHURST, From DESSA TREVISAN, From PAUL HOFMANN, Peter Evans, Peter Jay, From MICHAEL LEAPMAN, By STEPHEN JESSEL, PHS, G. D. S. BLACK, MALCOLM E. COOPER, JAMES GULLIVER, FRANK HAWKINS, JACQUES, HYMAN KREITMAN, JOHN SAINSBURY, WIGG., HUW WHELDON, GEORGE HOWARD, HUGH LEGGATT, CLAUDE ROGERS, C. J. HACKETT, ELIZABETH GORE, J. CAMPBELL, By James Morris, DONALD SWANN, PEREGRINE WORSTHORNE., I. G. COLLINS, A. E. PENNIFOLD, By GERALDINE KEEN, Lord Shawcross, A.C., W.W.S., By Irving Wardle, By Leonard Buckley, By William Mann, By Stanley Sadie, By Alan Blyth, By John Russell Taylor, Joan Chissell, Henry Stanhope, By Nature-Times News Service, by Antony King-Deacon, By MICHAEL PHILLIPS, Racing Correspondent, By our Racing Correspondent, By REX BELLAMY, Tennis Correspondent, By REX BELLAMY, From JOHN HENNESSY, From JOHN WOODCOCK, Cricket Correspondent, By NEIL ALLEN, Boxing Correspondent, BY JOYCE WHITEHEAD, By REX BELLAMY, Squash Rackets Correspondent, By GEOFFREY CHARLES, Motoring Correspondent, By GERALD ELY, By CLIFFORD WEBB, Midland Industrial Correspondent, By IAN MORISON, Banking Correspondent, By MICHAEL BAILY, Shipping Correspondent, By ROBERT JONES, By DAVID JONES, Political Staff, By MARGARET STONE, By MICHAEL THOMAS, Labour Correspondent, By RONALD KERSHAW, Northern Industrial Correspondent, From FRANK VOGL, From COLIN CHAPMAN, From ANTHONY THOMAS US Economics Correspondent, HUGH STEPHENSON, By JOHN CARRINGTON, BY THE FINANCIAL EDITOR, By PETER JAY, Economics Editor, By Clive Callow, By BERRY RITCHIE, Mining Editor, E. C. WILSON, J. MAYBANK, RICHARD WAY, E S I A W, EDITED BY KENNETH OWEN, BERRY RITCHIE, DAVID MILLHAM, GILLIAN GRAHAM,

News: Hogg's immigration guidelines, Moscow ban on play, Russians keeping up long border vigil, Underground men given new offer, The Times Diary Move ...

1970 - Gale Group | TDA

Artigo

Thomas M Drake, Cameron J Fairfield, Riinu Pius, Stephen R Knight, Lisa Norman, Michelle Girvan, Hayley E Hardwick, Annemarie B Docherty, Ryan S. Thwaites, Peter Openshaw, J. Kenneth Baillie, Ewen M. Harrison, Malcolm G. Semple, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Ana da Silva Filipe, Thushan I. de Silva, Annemarie B Docherty, Jake Dunning, Tom Fletcher, Christopher Green, Ewen M. Harrison, Julian A. Hiscox, Antonia YW Ho, Peter Horby, Samreen Ijaz, Say Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Shona C. Moore, Mahdad Noursadeghi, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, AA Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Chloe Donohue, Fiona Griffiths, Hayley Hardwick, Ronan A Lyons, Wilna Oosthuyzen, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Lisa Norman, Riinu Pius, Catherine A. Shaw, Marie Connor, Jo Ann Dalton, Carrol Gamble, Michelle Girvan, Sophie Halpin, Ewen M. Harrison, Clare Jackson, Laura Marsh, Stephanie Roberts, Egle Saviciute, Sara Clohisey, Ross Hendry, Andrew Law, Gary Leeming, James Scott-Brown, Murray Wham, William Greenhalf, Sara McDonald, Victoria Shaw, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Nicola Carlucci, Emily Cass, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Alejandra Doce Carracedo, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Lisa Flaherty, Terry Foster, Isabel García-Dorival, William Greenhalf, Philip Gunning, Catherine Hartley, Anthony Holmes, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Hannah Massey, Nicole Maziere, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Jihui Zhang, Alan Maclean, Sarah McCafferty, Kirstie Morrice, Lee Murphy, Nicola Wrobel, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary L. Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Thapas Nagarajan, Megan Nagel, Mark Nelson, Matthew K. O’Shea, Marlies Ostermann, Igor Otahal, Mark Pais, Selva Panchatsharam, Danai Papakonstantinou,

Early in the pandemic it was suggested that pre-existing use of non-steroidal anti-inflammatory drugs (NSAIDs) could lead to increased disease severity in patients with COVID-19. NSAIDs are an important analgesic, particularly in those with rheumatological disease, and are widely available to the general public without prescription. Evidence from community studies, administrative data, and small studies of hospitalised patients suggest NSAIDs are not associated with poorer COVID-19 outcomes. We aimed ...

Elsevier BV

Artigo

Thomas M Drake, Annemarie B Docherty, Ewen M. Harrison, Jennifer K Quint, Huzaifa Adamali, Sarah Agnew, Suresh Babu, Christopher Barber, Shaney Barratt, Elisabeth Bendstrup, Stephen Bianchi, Diego Castillo, Nazia Chaudhuri, Felix Chua, Robina Coker, William Chang, Anjali Crawshaw, Louise Crowley, Davinder Dosanjh, Christine Fiddler, Ian Forrest, Peter M. George, Michael Gibbons, Katherine Groom, Sarah Haney, Simon P. Hart, Emily Heiden, Michael T. Henry, Ling‐Pei Ho, Rachel K. Hoyles, John Hutchinson, Killian Hurley, Mark G. Jones, Steve Jones, Maria Kokosi, Michael Kreuter, Laura Mackay, Siva Mahendran, George Margaritopoulos, María Molina‐Molina, Philip L. Molyneaux, Aiden O’Brien, Katherine Ma O’Reilly, Alice Packham, Helen Parfrey, Venerino Poletti, Joanna C. Porter, Elisabetta Renzoni, Pilar Rivera‐Ortega, Anne‐Marie Russell, Gauri Saini, Lisa Spencer, Giulia Maria Stella, Helen Stone, Sharon Sturney, David Thickett, Muhunthan Thillai, Tim Wallis, Katie Ward, Athol U. Wells, Alex West, Melissa Wickremasinghe, Felix Woodhead, Glenn Hearson, Lucy Howard, J. Kenneth Baillie, Peter Openshaw, Malcolm G. Semple, Iain Stewart, Gisli Jenkins, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, A. A. Roger Thompson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Tom Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sarah E. McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, Willliam Greenhalf, Philip Gunning, Catherine Hartley, Antonia Ho, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah E. McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J. Eunice Zhang, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Brealey, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anita Holme, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall,

Rationale: The impact of coronavirus disease (COVID-19) on patients with interstitial lung disease (ILD) has not been established.Objectives: To assess outcomes in patients with ILD hospitalized for COVID-19 versus those without ILD in a contemporaneous age-, sex-, and comorbidity-matched population.Methods: An international multicenter audit of patients with a prior diagnosis of ILD admitted to the hospital with COVID-19 between March 1 and May 1, 2020, was undertaken and compared with patients without ...

American Thoracic Society

Artigo

Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Muhannad Alruwaili, Ghada T. Shawli, Tessa Prince, Maia Kavanagh Williamson, Jayna Raghwani, Nadine Randle, Benjamin Jones, I’ah Donovan-Banfield, Francisco J. Salguero, Julia A. Tree, Yper Hall, Catherine Hartley, Maximilian Erdmann, James Bazire, Tuksin Jearanaiwitayakul, Malcolm G. Semple, Peter Openshaw, J. Kenneth Baillie, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, Kanta Chechi, G Cooke, Ana da Silva Filipe, Thushan I. de Silva, Annemarie B Docherty, Gonçalo dos Santos Correia, Marc‐Emmanuel Dumas, Jake Dunning, Tom Fletcher, Chris Green, William Greenhalf, Julian L. Griffin, Rishi K. Gupta, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter W Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Matthew R. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Shona C. Moore, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L. Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, Caroline Sands, J T Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Olivia Swann, Zoltán Takáts, Panteleimon G. Takis, Richard S. Tedder, A. A. Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Fiona Griffiths, Wilna Oosthuyzen, Cara Donegan, Rebecca G. Spencer, Lisa Norman, Riinu Pius, Thomas M Drake, Cameron J. Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Daniel Plotkin, James Lee, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, Victoria Shaw, S. E. McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan J. Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, Philip J. Gunning, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, S. E. McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Jack Pilgrim, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Jihui Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Sarah McCafferty, Richard Clark, Angie Fawkes, Kirstie Morrice, Alan Maclean, Nicola Wrobel, Lorna Donnelly, Audrey Coutts, Katarzyna Hafezi, Louise MacGillivray, Tammy Gilchrist, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Colin Berry, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Christopher Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanandan Dushianthan, Tristan A. Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, D.J. Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael E. Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett,

Abstract Background The mutational landscape of SARS-CoV-2 varies at the dominant viral genome sequence and minor genomic variant population. During the COVID-19 pandemic, an early substitution in the genome was the D614G change in the spike protein, associated with an increase in transmissibility. Genomes with D614G are accompanied by a P323L substitution in the viral polymerase (NSP12). However, P323L is not thought to be under strong selective pressure. Results Investigation of P323L/D614G substitutions ...

BioMed Central

Artigo

Wanwisa Dejnirattisai, Jiandong Huo, Daming Zhou, Jiří Zahradník, Piyada Supasa, Chang Liu, Helen M. E. Duyvesteyn, Helen M. Ginn, Alexander J. Mentzer, Aekkachai Tuekprakhon, Rungtiwa Nutalai, Beibei Wang, Aiste Dijokaite-Guraliuc, Suman Khan, Ori Avinoam, Mohammad W. Bahar, Donal Skelly, Sandra Adele, Síle A. Johnson, Ali Amini, Thomas Ritter, Chris Mason, Christina Dold, Daniel Pan, Sara Assadi, Adam Bellass, Nicola Omo-Dare, David Koeckerling, Amy Flaxman, Daniel Jenkin, Parvinder K. Aley, Merryn Voysey, Sue Ann Costa Clemens, Felipe Gomes Naveca, Valdinete Alves do Nascimento, Fernanda Nascimento, Cristiano Fernandes da Costa, Paola Cristina Resende, Alex Pauvolid‐Corrêa, Marilda Mendonça Siqueira, Vicky L. Baillie, Natali Serafin, Gaurav Kwatra, Kelly da Silva, Shabir A. Madhi, Marta C. Nunes, Tariq Malik, Peter Openshaw, J. Kenneth Baillie, Malcolm G. Semple, Alain Townsend, Kuan-Ying A. Huang, Tiong Kit Tan, Miles W. Carroll, Paul Klenerman, Eleanor Barnes, Susanna Dunachie, Bede Constantinides, Hermione J. Webster, Derrick W. Crook, Andrew J. Pollard, Teresa Lambe, Neil G. Paterson, Mark A. Williams, David R. Hall, Elizabeth E. Fry, Juthathip Mongkolsapaya, Jingshan Ren, Gideon Schreiber, David I. Stuart, Gavin Screaton, Christopher P. Conlon, Alexandra Deeks, John Frater, Lisa Frending, Siobhan Gardiner, Anni Jämsén, Katie Jeffery, Tom Malone, Eloise Phillips, Lucy Rothwell, Lizzie Stafford, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, Kanta Chechi, G Cooke, Ana da Silva Filipe, Thushan I. de Silva, Annemarie B Docherty, Gonçalo dos Santos Correia, Marc‐Emmanuel Dumas, Jake Dunning, Tom Fletcher, Chris Green, William Greenhalf, Julian L. Griffin, Rishi K. Gupta, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Matthew R. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Shona C. Moore, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L. Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, Caroline Sands, J T Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Olivia Swann, Zoltán Takáts, Panteleimon G. Takis, Richard S. Tedder, AA Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Fiona Griffiths, Wilna Oosthuyzen, Cara Donegan, Rebecca G. Spencer, Lisa Norman, Riinu Pius, Thomas M. Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Daniel Plotkin, James Lee, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, Victoria Shaw, Sarah E. McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah E. McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Jinyan Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Sarah McCafferty, Richard Clark, Angie Fawkes, Kirstie Morrice, Alan Maclean, Nicola Wrobel, Lorna Donnelly, Audrey Coutts, Katarzyna Hafezi, Louise MacGillivray, Tammy Gilchrist, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Colin Berry, Nicola Best, Pieter Bothma, David Chadwick,

On 24th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B.1.1.529 was announced, containing far more mutations in Spike (S) than previously reported variants. Neutralization titers of Omicron by sera from vaccinees and convalescent subjects infected with early pandemic Alpha, Beta, Gamma, or Delta are substantially reduced, or the sera failed to neutralize. Titers against Omicron are boosted by third vaccine doses and are high in both vaccinated individuals and those infected ...

Cell Press

Artigo

Fiina Närhi, Ramani Moonesinghe, Susan D. Shenkin, Thomas M Drake, Rachel Mulholland, Cara Donegan, Jake Dunning, Cameron J Fairfield, Michelle Girvan, Hayley E Hardwick, Antonia Ho, Gary Leeming, Jonathan S Nguyen-Van-Tam, Riinu Pius, Clark D Russell, Catherine A. Shaw, Rebecca G Spencer, Lance Turtle, Peter Openshaw, J. Kenneth Baillie, Ewen M. Harrison, Malcolm G. Semple, Annemarie B Docherty, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, Kanta Chechi, G Cooke, Ana da Silva Filipe, Thushan I. de Silva, Annemarie B Docherty, Gon ̧alo dos Santos Correia, Marc‐Emmanuel Dumas, Jake Dunning, Tom Fletcher, Christopher Green, William Greenhalf, Julian L. Griffin, Rishi K Gupta, Ewen M. Harrison, Julian A Hiscox, Antonia YW Ho, Peter Horby, Samreen Ijaz, Say Khoo, Paul Klenerman, Andrew Law, Matthew R. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Shona C Moore, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L. Robertson, Clark D Russell, Vanessa Sancho-Shimizu, Caroline Sands, Janet T Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David Stuart, Charlotte Summers, Olivia Swann, Zoltan Takats, Panteleimon G. Takis, Richard S Tedder, AA Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Fiona Griffiths, Wilna Oosthuyzen, Cara Donegan, Rebecca G Spencer, Lisa Norman, Riinu Pius, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Daniel Plotkin, James Lee, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, Victoria Shaw, Sarah E McDonald, Seán Keating, Katie A. Ahmed, Jane A Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan J Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, A.G. Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, Philip Gunning, Catherine Hartley, Rebecca L Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J. Eunice Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Sarah McCafferty, Richard Clark, Angie Fawkes, Kirstie Morrice, Alan Maclean, Nicola Wrobel, Lorna Donelly, Audrey Coutts, Katarzyna Hafezi, Louise MacGillivray, Tammy Gilchrist, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Colin Berry, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird,

BackgroundDexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY trial publication on June 16, 2020, and to identify discrepancies in care.MethodsWe did an audit of clinical implementation of corticosteroids in a prospective, observational, cohort study in 237 UK acute care hospitals between March 16, 2020, and April 14, ...

Elsevier BV

Artigo

Rishi K. Gupta, Ewen M. Harrison, Antonia Ho, Annemarie B Docherty, Stephen R Knight, Maarten van Smeden, Ibrahim Abubakar, Marc Lipman, Matteo Quartagno, Riinu Pius, Iain Buchan, Gail Carson, Thomas M Drake, Jake Dunning, Cameron J Fairfield, Carrol Gamble, Christopher Green, Sophie Halpin, Hayley Hardwick, Karl Holden, Peter Horby, Clare Jackson, Kenneth A McLean, Laura Merson, Jonathan S. Nguyen‐Van‐Tam, Lisa Norman, Piero Olliaro, Mark G. Pritchard, Clark D Russell, James Scott-Brown, Catherine A. Shaw, Aziz Sheikh, Tom Solomon, Cathie Sudlow, Olivia Swann, Lance Turtle, Peter Openshaw, J. Kenneth Baillie, Malcolm G. Semple, Mahdad Noursadeghi, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, AA Roger Thompson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Tom Drake, Cameron J. Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, James Lee, Daniel Plotkin, Michelle Girvan, Scott Mullaney, Claire Petersen, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sarah McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, Willliam Greenhalf, Philip Gunning, Catherine Hartley, Antonia Ho, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Jihui Zhang, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Brealey, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary L. Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon,

BackgroundPrognostic models to predict the risk of clinical deterioration in acute COVID-19 cases are urgently required to inform clinical management decisions.MethodsWe developed and validated a multivariable logistic regression model for in-hospital clinical deterioration (defined as any requirement of ventilatory support or critical care, or death) among consecutively hospitalised adults with highly suspected or confirmed COVID-19 who were prospectively recruited to the International Severe Acute ...

Elsevier BV

Artigo

Annemarie B Docherty, Rachel Mulholland, Nazir Lone, Christopher P. Cheyne, Daniela De Angelis, Karla Díaz-Ordaz, Cara Donegan, Thomas M Drake, Jake Dunning, Sebastian Funk, Marta García‐Fiñana, Michelle Girvan, Hayley E Hardwick, Ewen M. Harrison, Antonia Ho, David M. Hughes, Ruth H. Keogh, Peter Kirwan, Gary Leeming, Jonathan S. Nguyen‐Van‐Tam, Riinu Pius, Clark D Russell, Rebecca G. Spencer, Brian D. M. Tom, Lance Turtle, Peter Openshaw, J. Kenneth Baillie, Ewen M. Harrison, Malcolm G. Semple, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Ewen M. Harrison, Julian A. Hiscox, Antonia YW Ho, Peter Horby, Samreen Ijaz, Say Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, AA Roger Thompson, Ryan S. Thwaites, Lance Turtle, Rishi K. Gupta, Carlo Palmieri, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Thomas M Drake, Cameron J. Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sarah E. McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan J. Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, William Greenhalf, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah E. McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, Jihui Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Kirstie Morrice, Alan Maclean, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul B. Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok,

Mortality rates in hospitalised patients with COVID-19 in the UK appeared to decline during the first wave of the pandemic. We aimed to quantify potential drivers of this change and identify groups of patients who remain at high risk of dying in hospital.

Elsevier BV

Artigo

Felicity Liew, Claudia Efstathiou, Sara Fontanella, Matthew Richardson, Ruth Saunders, Dawid Swieboda, Jasmin Sidhu, Stephanie Ascough, Shona C. Moore, Noura Mohamed, J Nunag, Clara King, Olivia C. Leavy, Omer Elneima, Hamish McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Victoria Harris, Linzy Houchen-Wolloff, Neil Greening, Nazir Lone, Matthew Thorpe, A. A. Roger Thompson, Sarah Rowland‐Jones, Annemarie B Docherty, James D. Chalmers, Ling‐Pei Ho, Alex Horsley, Betty Raman, Krisnah Poinasamy, Michael Marks, Onn Min Kon, Luke Howard, Dan Wootton, Jennifer K Quint, Thushan I. de Silva, Antonia Ho, Christopher Chiu, Ewen M. Harrison, William Greenhalf, J. Kenneth Baillie, Malcolm G. Semple, Lance Turtle, Rachael A. Evans, Louise V. Wain, Christopher E. Brightling, Ryan S. Thwaites, Peter Openshaw, Kathryn M. Abel, Huzaifa Adamali, Davies Adeloye, Oluwaseun Adeyemi, Rita Adrego, L A Aguilar Jimenez, Shanaz Ahmad, Nafees Haider, Rubina Ahmed, Nyarko Ahwireng, Mark Ainsworth, Asma Alamoudi, Mariam Ali, M Aljaroof, Louise Allan, Richard J. Allen, L. Allerton, Lynne Allsop, Ann Marie Allt, Paula Almeida, Bashar Al‐Sheklly, Daniel M. Altmann, Maria Alvarez Corral, Shannon Amoils, David Anderson, Charalambos Antoniades, Gill Arbane, Ava Maria Arias, Chérie Armour, Lisa Armstrong, Natalie Armstrong, David Arnold, H Arnold, Abdul Ashish, Andrew Ashworth, Milton Ashworth, Shahab Aslani, H Assefa-Kebede, Paul Atkin, Catherine Atkin, Raminder Aul, Hnin Aung, Liam Austin, Cristina Avram, Nikos Avramidis, A Ayoub, Marta Babores, Rhiannon R Baggott, J. Bagshaw, David Baguley, Elisabeth Bailey, J. Kenneth Baillie, Stephen C. Bain, Majda Bakali, M Bakau, Eileen Baldry, M Baldwin, David S. Baldwin, Clive Ballard, Amita Banerjee, Dongchun Bang, Ruth E Barker, L Barman, Perdita E. Barran, Shaney Barratt, Fiona Barrett, Donna Basire, Neil Basu, Michelle Bates, Andrew Bates, Rachel L. Batterham, Helen Baxendale, Gabrielle Baxter, Hannah Bayes, Michael Beadsworth, Paul Beckett, M. Beggs, M Begum, Paul Beirne, Murdina Bell, Robert M. Bell, Kaytie Bennett, Eva Beranová, Areti Bermperi, Anthony Berridge, Colin Berry, Sarah Betts, Emily Bevan, Kamaldeep Bhui, Michelle Bingham, K Birchall, Lettie Bishop, Karen Bisnauthsing, John Blaikely, Angela Bloss, Annette Bolger, Charlotte E. Bolton, James Bonnington, A Botkai, Charlotte Bourne, Michelle Bourne, Kate Bramham, Lucy Brear, Gerome Breen, Jonathon Breeze, K Breeze, Andrew Briggs, E Bright, Simon Brill, Khara Croswaite Brindle, Lauren Broad, A Broadley, Claire Brookes, Mattew Broome, Vanessa Brown, Mike Brown, Jo Brown, Jeremy Brown, Ammani Brown, Angela Brown, Mike Brown, Jeremy Brown, Traolach Brugha, Nigel J. Brunskill, Mamta Buch, Phil Buckley, Anda Bularga, Edward T. Bullmore, J Bunker, L. Burden, Tracy Burdett, David J. Burn, Graham Burns, A Burns, John Busby, Robyn Butcher, Al-Tahoor Butt, Suzanne Byrne, Paula Cairns, Philip C. Calder, E Calvelo, H Carborn, Bethany Card, Caitlin Carr, Liesel Carr, Gail Carson, Penny Carter, Anna Casey, Mark Philip Cassar, J. Cavanagh, Manish Chablani, Trudie Chalder, James D. Chalmers, Rachel C. Chambers, Flora Chan, Keith M. Channon, Kerry L. Chapman, Amanda Charalambou, Nazia Chaudhuri, Anna M. Checkley, Chen Jin, Yutung Cheng, L Chetham, Caroline E. Childs, Edwin R. Chilvers, Hector Chinoy, Amedeo Chiribiri, K Chong-James, Noura J. Choudhury, Gaunab Choudhury, Phil Chowienczyk, C D C Christie, M Chrystal, Cameron Clark, David Clark, Jude Clarke, Sara Clohisey, G Coakley, Zach Coburn, S Coetzee, Joby Cole, Chris Coleman, F Conneh, David Connell, Bronwen Connolly, Lynda Connor, Amanda Cook, Shirley Cooper, Brendan Cooper, Josh Cooper, Donna R. Copeland, Tracey Cosier, Eamon Coughlan, Martina Coulding, C Coupland, Eleanor Cox, Thelma Craig, Philippe Crisp, Daniele Cristiano, Michael G. Crooks, Andy Cross, Isabel Cf da Cruz, Paul Cullinan, Daniel J. Cuthbertson, Luke Daines, Matthhew Dalton, Patrick Daly, Alison Daniels, Paul Dark, Joanne Dasgin, David E. Cowley, Anthony S. David, Ffyon Davies, Ellie Davies, Kim Davies, Gareth Davies, Gwyneth A. Davies, Melanie J. Davies, Joy Dawson, Camilla Dawson, Enya Daynes, Anthony De Soyza, J.F.W. Deakin, Andrew Deans, C Deas, Joanne Deery, Sylviane Defres, Amanda Dell, K Dempsey, Emma Denneny, John Dennis, A Dewar, R Dharmagunawardena, N. Diar-Bakerly, Caroline Dickens, A Dipper, Sarah Diver, S N Diwanji, Myles Dixon, Ratko Djukanović, Hannah Dobson, Stephen L. Dobson, Annemarie B Docherty, A Donaldson, Tao Dong, Natalie Dormand, Andrew Dougherty,

One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood

Nature Portfolio

Artigo

Katharine A Relph, Clark D Russell, Cameron J Fairfield, Lance Turtle, Thushan I. de Silva, Matthew K. Siggins, Thomas M Drake, Ryan S. Thwaites, Simon T. Abrams, Shona C. Moore, Hayley Hardwick, Wilna Oosthuyzen, Ewen M. Harrison, Annemarie B Docherty, Peter Openshaw, J. Kenneth Baillie, Malcolm G. Semple, Antonia Ho, J. Kenneth Baillie, Malcolm G. Semple, Peter Openshaw, Gail Carson, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Annemarie B Docherty, Jake Dunning, Ana da Silva Filipe, Tom Fletcher, Christopher Green, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, A. A. Roger Thompson, Ryan S. Thwaites, Lance Turtle, Rishi K. Gupta, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sara McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, William Greenhalf, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J Eunice Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Kirstie Morrice, Alan Maclean, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chris Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Megan Nagel, Thapas Nagarajan, Mark Nelson,

Abstract Admission procalcitonin measurements and microbiology results were available for 1040 hospitalized adults with coronavirus disease 2019 (from 48 902 included in the International Severe Acute Respiratory and Emerging Infections Consortium World Health Organization Clinical Characterisation Protocol UK study). Although procalcitonin was higher in bacterial coinfection, this was neither clinically significant (median [IQR], 0.33 [0.11–1.70] ng/mL vs 0.24 [0.10–0.90] ng/mL) nor diagnostically useful ( ...

Oxford University Press

Artigo

Julie Bernhardt, Leonid Churilov, Fiona Ellery, Janice Collier, Jan Chamberlain, Peter Langhorne, Richard I. Lindley, Marj Moodie, Helen M. Dewey, Amanda G. Thrift, Geoffrey A. Donnan, Julie Bernhardt, Leonid Churilov, Janice Collier, Helen M. Dewey, Geoffrey A. Donnan, Fiona Ellery, Peter Langhorne, Richard I. Lindley, Marj Moodie, Brooke Parsons, Amanda G. Thrift, Geoffrey A. Donnan, Helen M. Dewey, Julie Bernhardt, Peter Langhorne, Marj Moodie, Brooke Parsons, Main Investigators MIs, Bent Indredavik, Torunn Askim, Phillip Bath, Christopher Bladin, Christopher M. Reid, Stephen Read, Catherine M. Said, Sandy Middleton, Judith Frayne, Velandai Srikanth, Julie Bernhardt, Helen M. Dewey, Julie Bernhardt, Geoffrey A. Donnan, Amanda G. Thrift, Rob Carter, Richard I. Lindley, Julie Bernhardt, Geoffrey A. Donnan, Richard I. Lindley, Amanda G. Thrift, Peter Langhorne, Marj Moodie, Helen M. Dewey, Leonid Churilov, Peter Langhorne, Peter Langhorne, Olívia Wu, Julie Bernhardt, Matthew Walters Claire Ritchie, L. D. Smith, Peter Langhorne, Olívia Wu, A. Ashburn, Helen Rodgers, Julie Bernhardt, Peter Langhorne, A. Ashburn, Julie Bernhardt, Helen Rogers, Olívia Wu, Sheila Lennon, Sheila Lennon, Michael Power, Julie Bernhardt, Shahul Hameed, Shahul Hameed, Pavanni Ratnagopal, Peter A.C. Lim, Julie Bernhardt, Dawn Tan, Leonid Churilov, Tim Brewer, Janice Collier, Nick Haritos, E Leong, Cecilia Li, Caesar NayWin, Marcus Nicol, Liudmyla Olenka, Li Chun Quang, Marj Moodie, Rob Carter, Silvia Hope, Lauren Sheppard, Kiusiang Tay- Teo, Olívia Wu, Toby Cumming, Thomas Lindén, Karen Borschmann, Jan Chamberlain, Janice Collier, Toby Cumming, Fiona Ellery, Teresa Occhiodoro, Helen Palfreeman, Tara Purvis, Bernadette Sirgo, Nick Tiliacos, John Van Holsteyn, Henry Zhao, Beverly Armstrong, Louise Craig, Fiona Graham, Lynn Legg, Rosemary Morrison, Heather Moorhead, Lorraine O’Donohue, Susan Rogers, Myra Smith, Denise Forshaw, Jane Fitzgerald, Evelyn Hibbert, R Melling, S. Petrolo, Tara Purvis, H Williamson MIs, Phillip S. Adams, L Augoustakis, S Batcheler, Sue Berney, Vera Cobani, Bernard A. Cohen, Helen M. Dewey, Stefania Di Gangi, N Giofre, Christopher J. Gordon, L Hegarty, M Hindson, F Horváth, Scott E. Kalinowski, Appie H. Kleine, Sharon Kramer, Jean M. Lawrence, S Lindquist, Nicola S. Logan, A. A. Macdonell, J Matlioski, N McDonough, Susan V. McLennan, Mike McNamee, Laura Miller, C. Nall, Elizabeth A. Nelson, Kimmie Ng, Z Nicholas, Caitlin Nunn, Katharine R. Owen, E Plant, Louise A Proud, Denise Desiree Bi Si Quah, K Rodway, S Sertori, V Sheldon, Lance Sherry, Sally Speare, K Stansfeld, N Studden, Zheyi Teoh, Lucy E. TWIST, G Velupillai, Laura Walker, Kylie Wall, Anne B. Warwick, R Wharrie, John Wilson, Hannah Worboys, David Young, Jiarun Mi, Maria Bryant, Bethany Doran, Michael J. Field, P Fogliani, A Háber, Graeme J. Hankey, Delia Hendrie, V Jackaman, A. S. Jacobsen, S Jose, R. Lim, Renée M. St. Louis, S. Nanthakumar, Scott Pain, Anne Power, B Rappeport, John Reynolds, L. D. Smith, S Tombe, Andrew Wesseldine, Tiffany West, Kristie E.N. Clarke, H Maccanti, Linsey C. Marr, Sandra Plumb, J Quiney, L Werner MIs, E Abeykoon, W Apirutvorrachod, Luciano Attard, S Behanan, David Brown, K. D. Buchanan, Donna Butler, M Camac, Stephen M. Davis, D Diocera, N Y Gan, C Gendre, Jacqueline Germaine, Peter J. Hand, L Maurenbrecher, J McCulloch, S Mcritchie, Michelle Ong, R Pachett, Lauren Pesavento, H.M. Power, Richard B. Reilly, M Sawers, G Silva, Christine Stevens, Lee Taylor, Tracy Timms, Melissa Ugalde, Audrey Vardy, Jana Wallace, S Walsh, E. Whatley, Edward Winter, Mark Baxter, Michelle Davis, Leyla Mıs, Ernest Butler, Kristin Caspers, Elizabeth J. Coulter, Stephen Shaw, Fiona Kent, H. Lambert Lack, F Leavold, Janet M. Lord, J Martin-Francisco, Rajiv Mohanraj, Randy Nelson, T O'Neill, R. M. Otto, Jane Parker, Vaughan W. Rees, Bonnie Stevens, Ru-Rong Mi, Richard I. Lindley, Jessica Bindra, Rohit Dongre, N Downey, Michael J. Ferris, Linda Gibson‐Young, Robert Gonzalez, M Kinniburgh, M. Lazaridou, D McCormack, Rajesh Kumar Singh, A Stepney, Y Tria, Kathleen E. Bainbridge, B Killey, R Sheedy MIs, O Aitchison, Lucy Bray, K Clatworthy, Sarah Coghill, Marissa Collins, L. Cornwall, Julian A. T. Dow, Peter Gates, Sarah Gillett, Niall Johnson, Sonia Joseph, K Kopelke, Ray Lam, Ronald Levy, N Lloyd, Stuart Logan, Gary E. McPherson, M Newth, Carl Parsons, K Powles, M Rebis, T Samakowidic,

Objective: Our prespecified dose-response analyses of A Very Early Rehabilitation Trial (AVERT) aim to provide practical guidance for clinicians on the timing, frequency, and amount of mobilization following acute stroke. Methods: Eligible patients were aged ≥18 years, had confirmed first (or recurrent) stroke, and were admitted to a stroke unit within 24 hours of stroke onset. Patients were randomized to receive very early and frequent mobilization, commencing within 24 hours, or usual care. We used regression ...

Lippincott Williams & Wilkins

Artigo

Chloë I. Bloom, Thomas M Drake, Annemarie B Docherty, Brian J. Lipworth, Sebastian L. Johnston, Jonathan S. Nguyen‐Van‐Tam, Gail Carson, Jake Dunning, Ewen M. Harrison, J. Kenneth Baillie, Malcolm G. Semple, Paul Cullinan, Peter Openshaw, Beatrice Alex, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, G Cooke, Ana da Silva Filipe, Tom Fletcher, Chris Green, Ewen M. Harrison, Julian A. Hiscox, Antonia Ho, Peter Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Wei Shen Lim, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Mahdad Noursadeghi, Shona C. Moore, Massimo Palmarini, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, J T Scott, Thushan I. de Silva, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Richard S. Tedder, Emma C. Thomson, AA Roger Thompson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Ronan A Lyons, Fiona Griffiths, Wilna Oosthuyzen, Lisa Norman, Riinu Pius, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Catherine A. Shaw, Jo Ann Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Ewen M. Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Gary Leeming, Andrew Law, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, William Greenhalf, Victoria Shaw, Sara McDonald, Seán Keating, Katie A. Ahmed, J. A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA Catterall, Jordan Clark, Emily A Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS Fisher, Terry Foster, Isabel García-Dorival, William Greenhalf, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A Livoti, Maria Vittoria Mancini, Sarah E. McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S Miah, Joanna Middleton, Joyce Mitchell, Shona C. Moore, E. Gordon Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J. Eunice Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Ana Alegria, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Nicola Best, Pieter Bothma, David Brealey, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary L. Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Megan Nagel, Thapas Nagarajan, Mark Nelson, Igor Otahal, Mark Pais, Selva Panchatsharam, Hassan Paraiso, Brij Patel, Natalie Pattison, Justin Pepperell, Mark Peters, Mandeep Phull, Stefania Pintus, Jagtur Singh Pooni, Frank A. Post, Ashley Price, Rachel Prout, Nikolas Rae, Henrik Reschreiter, Tim Reynolds, Neil Richardson, Mark Roberts, Devender Roberts, Alistair Rose,

Studies of patients admitted to hospital with COVID-19 have found varying mortality outcomes associated with underlying respiratory conditions and inhaled corticosteroid use. Using data from a national, multicentre, prospective cohort, we aimed to characterise people with COVID-19 admitted to hospital with underlying respiratory disease, assess the level of care received, measure in-hospital mortality, and examine the effect of inhaled corticosteroid use.We analysed data from the International Severe ...

Elsevier BV

Artigo

Thushan I. de Silva, Guihai Liu, Benjamin B. Lindsey, Danning Dong, Shona C. Moore, Sharon Hsu, Dhruv R. Shah, Dannielle Wellington, Alexander J. Mentzer, Adrienn Angyal, Rebecca Brown, Matthew Parker, Zixi Ying, Xuan Yao, Lance Turtle, Susanna Dunachie, Mala K. Maini, Graham S. Ogg, Julian C. Knight, Yanchun Peng, Sarah L. Rowland-Jones, Tao Dong, David M. Aanensen, Khalil Abudahab, Helen Adams, Alexander Adams, Safiah Afifi, Dinesh Aggarwal, Shazaad S.Y. Ahmad, Louise Aigrain, Adela Alcolea-Medina, Nabil-Fareed Alikhan, Elias Allara, Roberto Amato, Tara Annett, Stephen Aplin, Cristina V. Ariani, Hibo Asad, Amy Ash, Paula Ashfield, Fiona Ashford, Laura Atkinson, Stephen W. Attwood, Cressida Auckland, Alp Aydin, David Baker, Paul Baker, Carlos E. Balcazar, Jonathan Ball, Jeffrey C. Barrett, Magdalena Barrow, Edward Barton, Matthew Bashton, Andrew R. Bassett, Rahul Batra, Chris Baxter, Nadua Bayzid, Charlotte Beaver, Angela H. Beckett, Shaun M. Beckwith, Luke Bedford, Robert Beer, Andrew D. Beggs, Katherine L. Bellis, Louise Berry, Beatrice Bertolusso, Angus Best, Emma Betteridge, David C. Bibby, Kelly Bicknell, Debbie Binns, Alec Birchley, Paul Bird, Chloe Bishop, Rachel Blacow, Victoria Blakey, Beth Blane, Frances Bolt, James Bonfield, Stephen Bonner, David Bonsall, Tim Boswell, Andrew Bosworth, Yann Bourgeois, Olivia Boyd, Declan T. Bradley, Cassie Breen, Catherine Bresner, Judith Breuer, Stephen Bridgett, Iraad F. Bronner, Ellena Brooks, Alice Broos, Julianne R. Brown, Giselda Bucca, Sarah L. Buchan, David Buck, Matthew Bull, Phillipa Burns, Shirelle Burton-Fanning, Timothy Byaruhanga, Matthew Byott, Stephen Campbell, Alessandro M. Carabelli, James S. Cargill, Matthew Carlile, Silvia Carvalho, Anna Casey, Anibolina Castigador, Jana Catalan, Vicki Chalker, Nicola J. Chaloner, Meera Chand, Joseph Chappell, Themoula Charalampous, Wendy Chatterton, Yasmin Chaudhry, Carol Churcher, Gemma Clark, Philip Clarke, Benjamin J. Cogger, Kevin D. Cole, Jennifer Collins, Rachel Colquhoun, Thomas R. Connor, Kate F. Cook, Jason D. Coombes, Sally Corden, Claire Cormie, Nicholas Cortes, Marius Cotic, Seb Cotton, Simon Cottrell, Lindsay Coupland, MacGregor Cox, Alison Cox, Noel Craine, Liam Crawford, Aidan Cross, Matthew Crown, Dorian Crudgington, Nicola Cumley, Tanya Curran, Martin D. Curran, Ana da Silva Filipe, Gavin Dabrera, Alistair C. Darby, Rose K. Davidson, Alisha Davies, Robert M. Davies, Thomas P. Davis, Daniela De Angelis, Elen De Lacy, Leonardo de Oliveira Martins, Johnny Debebe, Rebecca Denton-Smith, Samir Dervisevic, Rebecca Dewar, Jayasree Dey, Joana Dias, Donald Dobie, Matthew J. Dorman, Fatima Downing, Megan Driscoll, Louis du Plessis, Nichola Duckworth, Jillian Durham, Kirstine Eastick, Lisa J. Easton, Richard Eccles, Jonathan Edgeworth, Sue Edwards, Kate El Bouzidi, Sahar Eldirdiri, Nicholas Ellaby, Scott Elliott, Gary Eltringham, Leah Ensell, Michelle J. Erkiert, Marina Escalera Zamudio, Sarah Essex, Johnathan M. Evans, Cariad Evans, William V. Everson, Derek Fairley, Karlie Fallon, Arezou Fanaie, Ben W. Farr, Christopher Fearn, Theresa Feltwell, Lynne Ferguson, Laia Fina, Flavia Flaviani, Vicki M. Fleming, Stephen R. Forrest, Ebenezer Foster-Nyarko, Benjamin H. Foulkes, Luke Foulser, Mireille Fragakis, Dan Frampton, Sarah François, Christophe Fraser, Timothy M. Freeman, Helen Fryer, Marc Fuchs, William Fuller, Kavitha Gajee, Katerina Galai, Abbie Gallagher, Eileen Gallagher, Eileen Gallagher, Marta Gallis, Amy Gaskin, Bree Gatica-Wilcox, Lily Geidelberg, Matthew Gemmell, Iliana Georgana, Ryan P. George, Laura Gifford, Lauren Gilbert, Sophia T. Girgis, Sharon Glaysher, Emily J. Goldstein, Tanya Golubchik, Andrea N. Gomes, Sónia Gonçalves, Ian Goodfellow, Scott Goodwin, Salman Goudarzi, Marina Gourtovaia, Clive Graham, Lee Graham, Paul R. Grant, Luke R. Green, Angie Green, Jane Greenaway, Richard D. Gregory, Martyn F. Guest, Rory Gunson, Ravi Kumar Gupta, Bernardo Gutiérrez, Sam Haldenby, William L. Hamilton, Samantha E. Hansford, Tanzina Haque, Kathryn Harris, Ian Harrison, Ewan M. Harrison, Jennifer Hart, John A. Hartley, William T. Harvey, M J Harvey, Mohammed O. Hassan-Ibrahim, Judith Heaney, Thomas Helmer, John Henderson, Andrew R. Hesketh, Jessica Hey, David Heyburn, Ellen E. Higginson, Verity Hill, Jack D. Hill, Rachel A. Hilson, Ember Hilvers, Matthew T. G. Holden, Amy Hollis, Christopher W. Holmes, Nadine Holmes, Alison Holmes, Richard Hopes, Hailey Hornsby, Myra Hosmillo, Catherine Houlihan, Hannah C. Howson‐Wells, Jonathan Hubb, Hannah Huckson, Warwick Hughes, Joseph Hughes, Margaret Hughes, Stephanie Hutchings, Giles Idle, Chris J. Illingworth, Robert Impey, Dianne Irish-Tavares, Miren Iturriza-Gomara, Rhys Izuagbe, Christopher Jackson, Ben Jackson, Leigh Jackson, Kathryn Jackson, David K. Jackson, Aminu S. Jahun, Victoria James, Keith James, Christopher Jeanes, Aaron R. Jeffries,

We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of recognition by epitope-specific T cells assessed by IFN-γ and cytotoxic killing assays. Complete loss of T cell responsiveness was seen due to Q213K in the A∗01:01-restricted CD8+ ORF3a epitope FTSDYYQLY207-215; due to P13L, P13S, and P13T in the B∗27:05-restricted ...

Cell Press

Artigo

Yanshan Zhu, Flávia Jacqueline Almeida, J. Kenneth Baillie, Asha C Bowen, Philip N Britton, Martín Brizuela, Danilo Buonsenso, David Burgner, Keng Yih Chew, Kulkanya Chokephaibulkit, Cheryl Cohen, Stephania A. Cormier, Nigel Crawford, Nigel Curtis, Camila Giuliana Almeida Farias, Charles F. Gilks, Anne von Gottberg, Diana Hamer, Daniel Jarovsky, Waasila Jassat, Ana Rita Jesus, Lisa S. Kemp, Benjawan Khumcha, Georgina McCallum, Jessica E. Miller, Rosa Morello, Alasdair Munro, Peter Openshaw, Srivatsan Padmanabhan, Wanatpreeya Phongsamart, Gary Reubenson, Nicole Ritz, Fernanda Rodrigues, Supattra Rungmaitree, Fiona M. Russell, Marco Aurélio Palazzi Safádi, Christoph Saner, Malcolm G. Semple, Daniella Gregória Bomfim Prado da Silva, Laíse Marine Moura de Sousa, Marília Diogo Moço Souza, Kirsten Spann, Sibongile Walaza, Nicole Wolter, Yao Xia, Daniel K. Yeoh, Heather J. Zar, Petra Zimmermann, Kirsty R. Short, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, William Barclay, Debby Bogaert, Meera Chand, Kanta Chechi, G Cooke, Ana da Silva Filipe, Thushan I. de Silva, Annemarie B Docherty, Gonçalo dos Santos Correia, Marc‐Emmanuel Dumas, Jake Dunning, Tom Fletcher, Christopher Green, William Greenhalf, Julian L. Griffin, Rishi K. Gupta, Ewen M. Harrison, Antonia YW Ho, Karl Holden, Peter W Horby, Samreen Ijaz, Say Khoo, Paul Klenerman, Andrew Law, Matthew R. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Alexander J. Mentzer, Laura Merson, Alison M Meynert, Shona C. Moore, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L. Robertson, Clark D Russell, Vanessa Sancho‐Shimizu, Caroline Sands, J T Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David I. Stuart, Charlotte Summers, Olivia Swann, Zoltán Takáts, Panteleimon G. Takis, Richard S. Tedder, A. A. Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance Turtle, Maria Zambon, Thomas M Drake, Cameron J Fairfield, Stephen R Knight, Kenneth A McLean, Derek Murphy, Lisa Norman, Riinu Pius, Catherine A. Shaw, Marie Connor, Jo Ann Dalton, Carrol Gamble, Michelle Girvan, Sophie Halpin, Ewen M. Harrison, Clare Jackson, James Lee, Laura Marsh, Daniel Plotkin, Stephanie Roberts, Egle Saviciute, Sara Clohisey, Ross Hendry, Susan Knight, Eva Lahnsteiner, Gary Leeming, Lucy Norris, James Scott-Brown, Sarah Tait, Murray Wham, Richard E. Clark, Audrey Coutts, Lorna Donelly, Angie Fawkes, Tammy Gilchrist, Katarzyna Hafezi, Louise MacGillivray, Alan Maclean, Sarah McCafferty, Kirstie Morrice, Lee Murphy, Nicola Wrobel, Gail Carson, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John C. Berridge, Colin Berry, Nicola Best, Pieter Bothma, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, David Chadwick, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanandan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Atul Garg, Effrossyni Gkrania–Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Tassos Grammatikopoulos, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Joanne Howard, Michael Jacobs, Susan Jain, Paul B. Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamás Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark D Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Enock Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Kavya Mohandas, Quen Mok, James Moon, Shona C. Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Thapas Nagarajan, Megan Nagel, Mark Nelson, Lillian Norris, Matthew K. O’Shea, Marlies Ostermann, Igor Otahal, Mark Pais, Selva Panchatsharam, Danai Papakonstantinou, Padmasayee Papineni, Hassan Paraiso, Brij Patel, Natalie Pattison, Justin Pepperell, Mark Peters, Mandeep Phull, Stefania Pintus, Tim Planche, Frank A. Post, Ashley Price, Rachel Prout, Nikolas Rae, Henrik Reschreiter, Tim Reynolds, Neil Richardson, Mark Roberts, Devender Roberts, Alistair Rose, Guy Rousseau, Bobby Ruge,

Importance Multiple SARS-CoV-2 variants have emerged over the COVID-19 pandemic. The implications for COVID-19 severity in children worldwide are unclear. Objective To determine whether the dominant circulating SARS-CoV-2 variants of concern (VOCs) were associated with differences in COVID-19 severity among hospitalized children. Design, Setting, and Participants Clinical data from hospitalized children and adolescents (younger than 18 years) who were SARS-CoV-2 positive were obtained from 9 countries ( ...

American Medical Association