Bart J. F. Keijser, Tim J. van den Broek, Dagmar Else Slot, Lodewic van Twillert, Jolanda Kool, Clémentine Thabuis, Michel Ossendrijver, G.A. van der Weijden, R.C. Montijn,
... of salivary flow and impacting oral pathogenic bacteria. Maltitol is often used as sweetener in food products. ... the in vivo effects of frequent consumption of maltitol sweetened chewing gum on the of dental plaque ... nl; NTR4165). One group was requested to use maltitol gum five times daily, one group used gum- ... abundance of several bacterial phylotypes was found in maltitol gum group compared to the gum base group, ... inhibition of A. massiliensis and A. johnsonii by maltitol at levels of 1% and higher. Transcriptome analysis ...
Tópico(s): Probiotics and Fermented Foods
2018 - Frontiers Media | Frontiers in Microbiology
Marko Petković, Biljana Pajin, Jelena Tomić,
Abstract Sucrose‐free spreads containing different share of maltitol (100, 70 and 30% as a bulking agents) ... with the aim to improve energy. Spreads with maltitol were produced in ball mill. The quality of ... The lowest energy values have spreads containing 100% maltitol. Spreads with maltitol do not have hygroscopic nature (moisture parameters are ... lowest size of largest particle. Spreads containing 100% maltitol have greater plastic viscosity and significant viscous properties. Dynamic oscillatory measurements showed the spreads with different maltitol share are the viscoelastic solids, with dominate elastic ...
Tópico(s): Proteins in Food Systems
2013 - Wiley | Journal of Food Process Engineering
AIJA‐MAARIA HIETALA LENKKERI, Kaisu Pienihäkkinen, Saija Hurme, Pentti Alanen,
... investigate the additional caries-preventive effect of xylitol/maltitol and erythritol/maltitol lozenges delivered at school, relative to controls receiving ... 4.7 g/4.6 g for xylitol/maltitol and 4.5 g/4.2 g for erythritol/maltitol. The groups received free examinations and care in ... to adjust for potential clustering.Use of xylitol/maltitol or erythritol/maltitol lozenges did not result in caries reduction. A ... caries conditions the school-based use of xylitol/maltitol or erythritol/maltitol lozenges would not have additional ...
Tópico(s): Endodontics and Root Canal Treatments
2011 - Wiley | International Journal of Paediatric Dentistry
Tsuneyuki Oku, Ryoko Hongo, S. Nakamura,
... design, we determined that osmotic diarrhea caused by maltitol ingestion was suppressed by the addition of not ... emptying in rats. Twenty-seven healthy volunteers ingested maltitol step-wise at doses of 15, 20, 25, ... out of 27 subjects experienced osmotic diarrhea from maltitol ingestion, and the minimal dose level of maltitol that induced osmotic diarrhea (MMD) was established for ... 0%). When a mixed solution of cellulose and maltitol was administered to rats, the gastric emptying of maltitol was significantly delayed at 30 and 60 min ...
Tópico(s): Polysaccharides Composition and Applications
2008 - Center for Academic Publications Japan | Journal of Nutritional Science and Vitaminology
S. Nakamura, Ryoko Hongo, Kazuhiko Moji, Tsuneyuki Oku,
... induced by ingestion of a sufficient amount of maltitol or lactitol in female subjects. The first, the minimal dose level of maltitol and lactitol that would induce transitory diarrhea was ... of PHGG and the minimal dose level of maltitol or lactitol. Laboratory of Public Health Nutrition, Department ... Incidence of diarrhea caused by the ingestion of maltitol or lactitol and the ratio of suppression achieved ... ingestion of amounts up to 45 g of maltitol, diarrhea caused in 29 of 34 subjects (85. ... caused diarrhea in 100%. The diarrhea owing to maltitol was improved in 10 of 28 subjects by ...
Tópico(s): Gastrointestinal motility and disorders
2007 - Springer Nature | European Journal of Clinical Nutrition
A. Ruskoné-Fourmestraux, A. Attar, D Chassard, Benoît Coffin, Francis Bornet, Yoram Bouhnik,
... usual pattern of consumption, 12 healthy volunteers ingested maltitol or sucrose throughout the day, either occasionally (once ... the mean TD was 92±6 g with maltitol and 106±4 g with sucrose (P=0. ... the mean TD was 93±9 g with maltitol and 113±7 g with sucrose (P=0. ... eight and three subjects, respectively (P=0.04). Maltitol and sucrose TDs between the two periods were ... to sucrose: (a) occasional or regular consumption of maltitol is not associated with severe digestive symptoms; (b) in both patterns of maltitol consumption, diarrhea frequency is higher, but it appeared ...
Tópico(s): Alcohol Consumption and Health Effects
2003 - Springer Nature | European Journal of Clinical Nutrition
Toshinao Goda, Kazuhiro Kishi, Ikuko Ezawa, Sachiko Takase,
Maltitol is a disaccharide alcohol that is produced by hydrogenation of maltose and exhibits resistance to intestinal disaccharidases. We demonstrated previously that maltitol stimulated transepithelial diffusional calcium transfer in the ileum, ... body. In this study we examined whether the maltitol-induced increase in the diffusional transfer of intestinal ... fed the diets containing either maltose (control) or maltitol and a requisite amount of calcium (0.52%) ... during the final 5-d period showed that maltitol-fed rats had greater calcium retention and calcium ...
Tópico(s): Digestive system and related health
1998 - Elsevier BV | Journal of Nutrition
Midoriko Tsukamura, Hidemi Goto, Tomiyasu Arisawa, Tetsuo Hayakawa, Naoya Nakai, Taro Murakami, Noriaki Fujitsuka, Yoshiharu Shimomura,
Maltitol is fermented in the colon due to only partial hydrolysis in the small intestine. In the present study, we examined effects of dietary maltitol on dimethylhydrazine-induced intestinal tumor in rats. In ... supplemented with 1 or 5 g/100 g maltitol for 27 wk. Each group of rats was ... the first 14 wk of the experimental period. Maltitol supplementation at 1 g/100 g of the ... the effect of the 1 g/100 g maltitol diet on the short chain fatty acid concentrations ... rats. Intake of the 1 g/100 g maltitol diet doubled (P < 0.05) the concentration of ...
Tópico(s): Biochemical Analysis and Sensing Techniques
1998 - Elsevier BV | Journal of Nutrition
D. M. Storey, G A Koutsou, A Lee, Albert Zumbé, Patrick Olivier, Y. Le Bot, Bernard Flourié,
... is known about the gastrointestinal effects of ingesting maltitol in chocolate. This study was designed to determine ... discover whether breath hydrogen excretion in response to maltitol is dose related. In a double-blind, crossover ... g sucrose, 10 g sucrose plus 30 g maltitol or 40 g maltitol after fasting (abstinence from food and liquids from ... symptomatology. Relative to ingestion of sucrose, 30 g maltitol caused no significant difference in symptoms, but 40 ... or severe symptoms. Neither 30 nor 40 g maltitol caused significantly greater laxation than sucrose ingestion (P > ...
Tópico(s): Nutritional Studies and Diet
1998 - Elsevier BV | Journal of Nutrition
Toshinao Goda, Kazuhito Suruga, Sachiko Takase, Ikuko Ezawa, Norimasa HOSOYA,
Maltitol is a disaccharide alcohol generated by hydrogenation of maltose and exhibiting resistance to intestinal disaccharidases. We demonstrated previously that maltitol stimulates transepithelial transport of calcium in the ileum, ... body. In this study, we examined whether the maltitol-induced increase in intestinal calcium absorption leads to ... diets containing either 10% maltose (control) or 10% maltitol, together with increased amounts of calcium (0.3% ... Experiment 2) period of the experiments showed that maltitol increased intestinal calcium absorption and retention. The breaking ...
Tópico(s): Muscle metabolism and nutrition
1995 - Elsevier BV | Journal of Nutrition
Toshinao Goda, Sachiko Takase, Norimasa HOSOYA,
To gain an insight into a mechanism whereby maltitol increases intestinal absorption of calcium, we evaluated transepithelial ... by comparing the values in the presence of maltitol with the values in the presence of maltose. ... the incubations in the medium containing 100 mM maltitol and in the medium containing 100 mM maltose, ... everted ileal segments incubated in the presence of maltitol exhibited two-fold greater transepithelial calcium transport than ... a low (0.5 mM) concentration of calcium, maltitol did not produce a significant effect. With the ...
Tópico(s): Drug Transport and Resistance Mechanisms
1993 - Center for Academic Publications Japan | Journal of Nutritional Science and Vitaminology
R. H. P. Lian‐Loh, G. G. Birch, Marie E. Coates,
... single oral dose of 1 or 2 g maltitol. Urine and faeces were collected during the following 24 h and their contents of maltitol and sorbitol were measured. 2. Very little of ... sorbitol found in the urine indicated that the maltitol had been hydrolysed. 3. Excretion of maltitol and sorbitol was compared in germ-free and ... rats given an oral dose of 2 g maltitol. Significantly less of both substances was recovered in ... urinary excretion was similar in both environments. 4. Maltitol injected intravenously gave rise to only traces of ...
Tópico(s): Alkaloids: synthesis and pharmacology
1982 - Cambridge University Press | British Journal Of Nutrition
Tsuneyuki Oku, Soon Hi HIM, Norimasa HOSOYA,
The activity and localization of hydrolysis enzyme of maltitol and the effect of maltose on maltitol hydrolysis were studied using the rat intestinal mucosa. The utilization of maltitol was, further, observed in the fasted and in ... were as follows:1. The hydrolysis activity to maltitol was highest in the jejunum and was about one-twentieth of that to maltose.2. The maltitol hydrolysis by jejunal enzyme was strongly inhibited in ... presence of maltose.3. It was suggested that maltitol was slowly hydrolyzed by maltase.4. When the ...
Tópico(s): Protein Hydrolysis and Bioactive Peptides
1981 - Japan Society of Nutrition and Food Science | Eiyo to shokuryo/Eiyo To Shokuryo
Setsuko YOSHIZAWA, Sachiko MORIUCHI, Norimasa HOSOYA,
... The highest disaccharidase activity for sucrose, maltose and maltitol was found in the jejunum, followed by the ileum and duodenum. However, the disaccharidase activity for maltitol was extremely low compared with that for sucrose and maltose. 2. For maltitol, the Km value was very large and the ... velocity (v) in the presence of sucrose and maltitol, was equal to the sum of the rates for individual substrates sucrose and maltitol (v1, v2) respectively (v=v1+v2). Thus, no ... was observed. In the case of maltose and maltitol, the initial velocity (v) in the presence of ...
Tópico(s): Pancreatic function and diabetes
1975 - Center for Academic Publications Japan | Journal of Nutritional Science and Vitaminology
P. Würsch, B Koellreutter, F. Gétaz, Maurice J. Arnaud,
The metabolism of maltitol (4-α-D-glucosylsorbitol) was assessed in fasting conventional (C) rats, C mice and germ-free (GF) mice, using [U- 14 C]maltitol. The radiorespirometric patterns of 14 CO 2 collected for 48 h after the administration of labelled maltitol were characterized by a constant rate of 14 ... 39% in the GF mice. The digestibility of maltitol and the absorption of sorbitol in GF mice ... 3 h after administration of equimolar quantities of maltitol (140 mg/kg body-weight) or sorbitol (70 ... of mice and rats are sufficient to hydrolyse maltitol extensively. Consequently, the slow absorption of sorbitol seems ...
Tópico(s): Microbial Metabolites in Food Biotechnology
1990 - Cambridge University Press | British Journal Of Nutrition
Semir Canimoĝlu, Eyyüp Rencüzoğulları,
... cytotoxic effects of the low-caloric artificial sweetener maltitol, which is a sugar alcohol (polyol), were investigated ... test. In addition, the teratogenicity and embryotoxicity of maltitol was also investigated in rats. To reveal the genotoxicity and cytotoxicity of maltitol, rats were intraperitoneally administered 2.5, 5 and 10 g/kg body weight (bw) concentrations of maltitol for 6, 12 and 24 h treatment period. ... and 4 g/kg bw/day concentrations of maltitol during the first 7 days of gestation (first ...
Tópico(s): GABA and Rice Research
2012 - SAGE Publishing | Toxicology and Industrial Health
... the synthesized ZIF-8 nanoparticles embedded into a maltitol-modified Pebax®1657. Maltitol (as an inexpensive low molecular weight additive) provides ... were added (0–10 wt%) into the Pebax/maltitol (20 wt%) matrix to prepare the Pebax/maltitol/ZIF-8 MMMs. Field Emission Scanning electron microscopy ( ... 30 °C and 10 bar revealed that Pebax/maltitol (20 wt%)/ZIF-8 (10 wt%) membrane showed ... and CO2/CH4 separation, respectively; obtained by Pebax/maltitol (20 wt%)/ZIF-8 (5 wt%) at 30 ° ... and 10 bar. Finally, the performance of Pebax/maltitol (20 wt%)/ZIF-8 (5 wt%) membrane was ...
Tópico(s): Synthesis and properties of polymers
2022 - Elsevier BV | Process Safety and Environmental Protection
Shiyong Ding, Bo Peng, Youqian Li, Jun Yang,
The influence of maltitol on the physicochemical properties of wheat flour dough and bread were evaluated in terms of texture, thermal features, water mobility, and retrogradation kinetics. The presence of maltitol could slow down the fermentation rate of dough. Breads with 6% of maltitol exhibited lower hardness and chewiness, with a significant ... 31%, respectively (p < 0.05). The use of maltitol could remarkably enhance the gelatinization temperature (p < 0. ... the approach of LF-NMR, the addition of maltitol could increase the mobility of immobilized water, further ...
Tópico(s): Food Quality and Safety Studies
2019 - Elsevier BV | Food Chemistry
Mingyang Chen, Songgu Wu, Weiwei Tang, Junbo Gong,
Caking is a common phenomenon of maltitol that causes problems of separation, processing and transportation. To study the mechanism of caking, method of capillary rise was used to measure the contact angles between maltitol particles and relevant liquids. Based on the calculation of adhesion free energy of maltitol particles in different liquids by Lifshitz–van der ... the relationship between adhesion free energy and the maltitol particles size has been established. It is concluded that the adhesion free energy of maltitol with rinsing liquid plays a key role in ...
Tópico(s): Chemical and Environmental Engineering Research
2014 - Elsevier BV | Powder Technology
M. Siniti, S. Jabrane, J.M. Letoffé,
... to investigate the thermal behaviour of sorbitol, mannitol, maltitol and to establish the following phase diagrams: sorbitol/mannitol, sorbitol/maltitol, sorbitol/water and maltitol/water. Pure sorbitol and maltitol (4-Oα-glucopyranosyl-D-glucitol) vitrified uniquely upon ... the two states. For sorbitol/mannitol and sorbitol/maltitol mixtures, the equilibrium phases could not be obtained ( ... in our conditions (synthetic preparation of samples). The maltitol/water phase diagram presented simpler behavior than sorbitol/ ...
Tópico(s): Analytical Chemistry and Chromatography
1999 - Elsevier BV | Thermochimica Acta
Masahiro Fukahori, Hidetomo Sakurai, Sakae Akatsu, Munehiro Negishi, Hiroshi Sato, Toshinao Goda, Sachiko Takase,
The enhancing effects of maltitol (alpha-D-glucopyranosyl-1,4-sorbitol) on absorption of calcium by the rat intestine have been studied by use of [ ... After intragastric administration of [45Ca]CaCl2 solution with maltitol, plasma 45Ca concentration remained at the maximum level ... whereas for animals given [45Ca]CaCl2 solution without maltitol, plasma 45Ca concentration declined sharply after the peak. ... of the gastrointestinal tract revealed that administration of maltitol elicited slower gastric emptying and slower intestinal transit, ...
Tópico(s): Gastrointestinal motility and disorders
1998 - Oxford University Press | Journal of Pharmacy and Pharmacology
Toshinao GODA, M Yamada, Sachiko Takase, Norimasa HOSOYA,
... 66% starch) or the diets containing either 10% maltitol, 10% sorbitol or 10% lactose. At 2 and ... to 5-day-period calcium balance study. Feeding maltitol diets as well as sorbitol diet led to ... used in the present study. To explore whether maltitol can exert its effect in a short period ... containing 0.44% calcium together with either 10% maltitol or 10% glucose. The total calcium remaining in ... feeding was significantly decreased in the rats given maltitol diet as compared to the rats given glucose ... 45CaCl2 was given orally with the diets containing maltitol or glucose, the amount of 45Ca remaining in ...
Tópico(s): Biochemical Analysis and Sensing Techniques
1992 - Center for Academic Publications Japan | Journal of Nutritional Science and Vitaminology
J. P. Felber, Luc Tappy, Dominique Vouillamoz, J. P. Randin, E Jéquier,
The metabolism of the hydrogenated disaccharide maltitol was compared to that of sucrose in a group of eight normal subjects. On two separate days, with an interval of at ... the delta glucose concentration was significantly smaller after maltitol than after sucrose (21 ± 4 us 38 ± 4 ... 9.3 ± 2.7 μ U/ml after maltitol vs 25.5 ± 5.0 μU/ml after ... sucrose and 90 min after the load of maltitol. The delta glucose oxidation was significantly lower with maltitol than with sucrose during the first 90 min ... It was slightly higher (although not significantly) with maltitol than with sucrose starting from the 210th min. ...
Tópico(s): Metabolism and Genetic Disorders
1987 - Wiley | Journal of Parenteral and Enteral Nutrition
Clémentine Thabuis, Murielle Cazaubiel, Matthieu Pichelin, Daniel Wils, Laetitia Guérin‐Deremaux,
... industries because of their technological and nutritional properties. Maltitol is known for its non-acidogenic and low- ... objective was to evaluate the digestive tolerance of maltitol in children. The secondary objective was to compare the organoleptic properties of maltitol and sucrose in chocolate.Method Healthy children were ... placebo. The subjects received one dose of either maltitol or sucrose chocolate per week. Increasing doses were tested from 5 to 15 g maltitol in chocolate. Abdominal pain, rumbling, bloating and flatulence ...
Tópico(s): Food composition and properties
2010 - Taylor & Francis | International Journal of Food Sciences and Nutrition
Min Huang, Yihan Mao, Yuzhu Mao, Hongshun Yang,
... ingredients is critical. The effects of xylitol and maltitol (up to 30 wt %) on the rheological and ... from 44.1 to 61.4 °C in maltitol systems. With the increasing concentration of both xylitol and maltitol, the values of fractal dimension df and complex ... xylitol and 0.87 to 0.78 of maltitol, respectively. These indicated that the gel networks of ... were improved by the addition of xylitol and maltitol. The FTIR results showed that the interaction between ... the increase of hydrogen bonds. The effects of maltitol on κ-C were stronger than those of ...
Tópico(s): Proteins in Food Systems
2021 - Multidisciplinary Digital Publishing Institute | Foods
Semir Canimoĝlu, Eyyüp Rencüzoğulları,
The effects of the low-calorie artifical sweetener maltitol (E965), a sugar alcohol (Polyol), on sister chromatid ... formation (MN) were investigated in human peripheral lymphocytes. Maltitol did not induce SCE at all concentrations (1. ... mL) and treatment periods (24 and 48 h). Maltitol induced CA, although not statistically significantly. Maltitol induced the frequency of MN at 24 and ... in a non-dose-dependent manner. In addition, maltitol did not decrease the replication index (RI) and ... index (MI) at all concentrations and treatment periods. Maltitol did not alter the pH and osmolality of ...
Tópico(s): GABA and Rice Research
2006 - Taylor & Francis | Drug and Chemical Toxicology
Sonali Shirke, Pavlo Takhistov, Richard D. Ludescher,
... dispersed in amorphous thin films of maltose and maltitol at mole ratios of 0.8:10(4) ... C below T(g) in both maltose and maltitol; the relaxation rate, however, while 3-4 orders ... and increased dramatically at the T(g); in maltitol k(TS0) increased moderately at T(g) = -50 ... C. The value of k(TS0) in maltose:maltitol mixtures was significantly smaller than that seen in pure maltose and maltitol, suggesting that specific interactions decreased the mobility of ... increased dramatically in maltose and more gradually in maltitol at the glass transition.
Tópico(s): Material Dynamics and Properties
2005 - American Chemical Society | The Journal of Physical Chemistry B
Tsuneyuki Oku, Masanori AKIBA, Myung Hee LEE, Soo Jae MOON, Norimasa HOSOYA,
... a single oral dose of 0.4g of maltitol per kg body weight containing [U-14C]-maltitol (50μCi) and their breath, urine, feces and blood ... hydrogen, 15 healthy male subjects ingested 30g of maltitol and samples of their breath were collected for ... breath hydrogen was detected at 1 h after maltitol ingestion and then a big peak at 3. ... results demonstrate that a greater part of ingested maltitol is fermented by intestinal microbes than is hydrolyzed by diges-tive enzymes. Although maltitol is catabolized to carbon dioxide via intestinal microbes, ...
Tópico(s): Muscle metabolism and nutrition
1991 - Center for Academic Publications Japan | Journal of Nutritional Science and Vitaminology
M. W. Kearsley, G. G. Birch, R. H. P. Lian‐Loh,
... years in diabetic foods. Some metabolic effects of maltitol (hydrogenated maltose), which is a major component in ... concerns physiological studies of hydrogenated glucose syrups and maltitol in animals and human subjects. In rats it has been shown that maltitol is utilized in some quantity by the gut ... between conventional and germ‐free animals. Intravenously injected maltitol is excreted almost quantitatively in the urine producing ... studies indicate that although after an oral dose maltitol and hydrogenated glucose syrup induce lowered blood glucose ...
Tópico(s): Metabolism, Diabetes, and Cancer
1982 - Wiley | Starch - Stärke
A. Rérat, P. Vaissade, P. Vaugelade,
... 6% maltose, 5.2% free glucose) or a maltitol-rich hydrogenated glucose syrup (54.2% maltitol, 6% free sorbitol). For 8 h after the ... for the analysis of aminonitrogen, glucose and sorbitol. Maltitol was hydrolyzed substantially in the small gut. The ... was the same 8 h after infusion of maltitol (78.1%) and maltose (78.8%). Sorbitol was ... during the first 4 h after infusion of maltitol than after that of maltose. This was probably ... amount of glucose in the digestive lumen after maltitol hydrolysis.
Tópico(s): Diet and metabolism studies
1991 - Elsevier BV | Journal of Nutrition