Produção Nacional
Revisado por pares
Malu Siqueira Borges, Larissa Rodrigues Souto, Ariel F. Martinez, Fábio Viadanna Serrão, Marcos de Noronha,
This systematic review investigated whether people with patellofemoral osteoarthritis (PFOA) have muscle strength, volume, and activation around the hip and knee that is different from asymptomatic controls.Searches were carried out in five electronic databases, with terms related to PFOA, including muscle strength, volume and activation. Only studies with at least one group with symptomatic PFOA and one asymptomatic group were included. The methodological quality of the studies was assessed using ...
Tópico(s): Total Knee Arthroplasty Outcomes
2022 - Elsevier BV | Osteoarthritis and Cartilage
Produção Nacional
Revisado por pares
Anna Glória Fonseca Teodoro, Wellington Francisco Rodrigues, Thaís Soares Farnesi-de-Assunção, Anna Victória Bernardes e Borges, Malú Mateus Santos Obata, José Rodrigues do Carmo Neto, Djalma A. Alves da Silva, Leonardo Eurípedes Andrade-Silva, Chamberttan Souza Desidério, Juliana Cristina Costa-Madeira, Rafaela Miranda Barbosa, Andrezza Cristina Cancian Hortolani, Loren Queli Pereira, Fernanda Bernadelli De Vito, Sarah Cristina Sato Vaz Tanaka, Fernanda Rodrígues Helmo, Marcela Rezende Lemes, Laís Milagres Barbosa, Rafael Obata Trevisan, Fabiano Vilela Mundim, Ana Carolina de Morais Oliveira-Scussel, Paulo Roberto Resende, Ivan Borges Monteiro, Yulsef M. Ferreira, Guilherme H. Machado, Kennio Ferreira‐Paim, Hélio Moraes‐Souza, Carlo José Freire Oliveira, Virmondes Rodrigues, Marcos Silva,
SARS-CoV-2 (COVID-19) infection is responsible for causing a disease with a wide spectrum of clinical presentations. Predisposition to thromboembolic disease due to excessive inflammation is also attributed to the disease. The objective of this study was to characterize the clinical and laboratory aspects of hospitalized patients, in addition to studying the pattern of serum cytokines, and associate them with the occurrence of thromboembolic events. Methodology: A retrospective cohort study with ...
Tópico(s): Long-Term Effects of COVID-19
2023 - Multidisciplinary Digital Publishing Institute | Viruses
Produção Nacional
Revisado por pares
Rafaela Miranda Barbosa, Malú Mateus Santos Obata, José Rodrigues do Carmo Neto, Rhanoica Oliveira Guerra, Anna Victória Bernardes e Borges, Rafael Obata Trevisan, Letícia Cirelli Ruiz, Júlia de Moura Bernardi, Ana Carolina de Morais Oliveira-Scussel, Sarah Cristina Sato Vaz Tanaka, Fernanda Bernadelli De Vito, Fernanda Rodrígues Helmo, Thaís Soares Farnesi-de-Assunção, Juliana Reis Machado, Carlo José Freire Oliveira, Virmondes Rodrigues, Anielle Christine Almeida Silva, Marcos Silva,
Tegumentary leishmaniasis (TL) is caused by parasites of the genus Leishmania. Leishmania braziliensis (L.b) is one of the most clinically relevant pathogens that affects the skin and mucosa, causing single or multiple disfiguring and life-threatening injuries. Even so, the few treatment options for patients have significant toxicity, high dropout rates, high cost, and the emergence of resistant strains, which implies the need for studies to promote new and better treatments to combat the disease. ...
Tópico(s): Nanoparticles: synthesis and applications
2022 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Produção Nacional
Lucas Ciucio Giovanazzi, Maria Elisa Philippsen Missner, Isadora Bertini Martins Francisco, Núbia Malú Medeiros Rodrigues, Afonso Henrique da Silva Júnior, Leandro Pellenz, Cátia Rosana Lange de Aguiar, Carlos Rafael Silva de Oliveira,
The photocatalytic degradation of textile dyes using metallic oxides has been extensively studied due to the remarkable results. This promising approach offers a more sustainable alternative for treating textile effluents contaminated with dyes and other chemicals, intending to mitigate the environmental impact caused by the textile industry. In this context, this study aimed to investigate the degradation of different classes of synthetic dyes used in industry through the heterogeneous photocatalysis ...
Tópico(s): Water and Wastewater Treatment
2024 - Brazilian Journal of Development | Brazilian Journal of Animal and Environmental Research
Produção Nacional
Revisado por pares
Nathália Carolina Fernandes Fagundes, Miquéias André Gomes Cardoso, Mayara Sabrina Luz Miranda, Raíra de Brito Silva, Francisco Bruno Teixeira, Bárbara Catarina Lima Nogueira, Brenna Magdalena Lima Nogueira, Sara Elisama Silva de Melo, Natacha Malu Miranda da Costa, Rafael Rodrigues Lima,
This study aims to describe and analyze morphological and physical properties of deciduous teeth of Sus domesticus. Ultrastructural analysis, mineral composition and microhardness of enamel and dentine tissues were performed on 10 skulls of S. domesticus. External anatomic characteristics and the internal anatomy of the teeth were also described. Data regarding microhardness and ultrastructural analysis were subjected to statistical tests. For ultrastructural analysis, we used the analysis of variance ( ...
Tópico(s): Dental materials and restorations
2015 - Elsevier BV | Annals of Anatomy - Anatomischer Anzeiger
Produção Nacional
Revisado por pares
Gabriela B. da Silva, Lucas S da Faria, Camila de Almeida Lopes, Daniela Nunes, Vanessa da Silva Ribeiro, José Eduardo Neto de Sousa, Guilherme Carrara Moreira Paiva, M. R. F. Gonçalves-Pires, Isabela Pacheco Borges, Malú Mateus Santos Obata, Veridiana de Melo Rodrigues, Álvaro Ferreira Júnior, Julia Maria Costa‐Cruz,
Neurocysticercosis (NCC) is a neglected tropical disease and its diagnosis is still a challenge due to non-specific manifestations. Neuroimaging techniques are used in the diagnosis of NCC, however, due to the high cost of these methods and the advantages presented in the use of immunological tests, such as ease of performance and satisfactory results, immunoassays are commonly used to detect antibodies against Taenia sp. antigens. The aim of the present study was to produce, characterize and apply ...
Tópico(s): Food Allergy and Anaphylaxis Research
2020 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Produção Nacional
Revisado por pares
Guilherme Carrara Moreira Paiva, Gabriela B. Silva, Lucas Silva de Faria, Daniela Nunes, Vanessa da Silva Ribeiro, Camila de Almeida Lopes, Maria do Rosário F. Gonçalves-Pires, Malú Mateus Santos Obata, Isabela Pacheco Borges, Álvaro Ferreira Júnior, Veridiana de Melo Rodrigues, Julia Maria Costa‐Cruz,
Abstract Human neurocysticercosis (NCC) is a worldwide neglected disease caused by Taenia solium metacestode and responsible for various complications and neurological disorders. This study aimed to evaluate the use of specific immunoglobulin Y (IgY) produced by laying hens immunized with a hydrophobic fraction of Taenia crassiceps metacestodes (hF Tc ) in NCC diagnosis. Egg yolk IgY antibodies were fractionated, purified and characterized. Enzyme-linked immunosorbent assay (ELISA) was carried out to ...
Tópico(s): Parasites and Host Interactions
2019 - Cambridge University Press | Parasitology
Produção Nacional
Revisado por pares
Francisco Bruno Teixeira, Rafael M. Fernandes, Paulo Mecenas, Natacha Malu Miranda da Costa, Luanna Melo Pereira Fernandes, Luana Santana, Ademir Ferreira da Silva-Júnior, Marcia Silva, Cristiane do Socorro Ferraz Maia, Rafael Rodrigues Lima,
The aims of this study were to evaluate whether chronic intoxication with mercury chloride (HgCl2), in a low concentration over a long time, can be deposited in the central nervous tissue and to determine if this exposure induces motor and cognitive impairments. Twenty animals were intoxicated for 45 days at a dose of 0.375 mg/kg/day. After this period, the animals underwent a battery of behavioral tests, in a sequence of open field, social recognition, elevated T maze and rotarod tests. They were ...
Tópico(s): Heavy Metal Exposure and Toxicity
2014 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Produção Nacional
Revisado por pares
Thaís Amanda de Lima Nunes, Malú Mateus Santos Obata, Mariana Silva Oliveira, Julyanne Maria Saraiva de Sousa, Raiza Raianne Luz Rodrigues, Paulo Sérgio de Araújo Sousa, Alyne Rodrigues de Araújo, Anna Carolina Toledo da Cunha Pereira, Gustavo Portela Ferreira, Jefferson Almeida Rocha, Virmondes Rodrigues, Marcos Silva, Klinger Antônio da França Rodrigues,
Leishmaniasis is a set of infectious diseases with high rates of morbidity and mortality, it affects millions of people around the world. Treatment, mainly with pentavalent antimonials, presents significant toxicity and many cases of resistance. In previous works we have demonstrated the effective and selective antileishmanial activity of Eugenia uniflora L. essential oil, being constituted (47.3%) by the sesquiterpene curzerene. Considering the high rate of parasite inhibition demonstrated for E. ...
Tópico(s): Cynara cardunculus studies
2021 - Elsevier BV | International Immunopharmacology
Produção Nacional
Revisado por pares
Cecília Gomes Barbosa, Tamires Marielem Carvalho Costa, Chamberttan Souza Desidério, Paula Tatiana Mutão Ferreira, Mariana de Oliveira Silva, César Gómez‐Hernández, Malú Mateus Santos Obata, Rafael Obata Trevisan, Weslley Guimarães Bovi, Virmondes Rodrigues, Juliana Reis Machado, Luiz Eduardo Ramirez, Carlo José Freire Oliveira, Marcos Silva,
Dendritic cells (DCs) are a type of antigen-presenting cells that play an important role in the immune response against Trypanosoma cruzi, the causative agent of Chagas disease. In vitro and in vivo studies have shown that the modulation of these cells by this parasite can directly affect the innate and acquired immune response of the host in order to facilitate its biological cycle and the spreading of the species. Many studies show the mechanisms by which T. cruzi modulates DCs, but the interaction ...
Tópico(s): Parasitic Infections and Diagnostics
2019 - Hindawi Publishing Corporation | Mediators of Inflammation
Produção Nacional
Revisado por pares
Priscila Cristina Bartolomeu Halicki, Júlia Silveira Vianna, Nilo Zanatta, Valquiria P. Andrade, Mariana de Oliveira, Malú Mateus Santos Obata, Marcos Silva, Virmondes Rodrigues, Daniela Fernandes Ramos, Pedro Eduardo Almeida da Silva,
Although the administration of combined therapy is efficient to tuberculosis (TB) treatment caused by susceptible Mycobacterium tuberculosis strains, to overcome the multidrug resistance is still a challenge. Some studies have reported evidence about tetrahydropyridines as a putative efflux pump inhibitor, including in mycobacteria, being a promising strategy against M. tuberculosis. Thus, we investigated the biological potential of 2,2,2-trifluoro-1-(1,4,5,6-tetrahydropyridin-3-yl)ethanone derivative ( ...
Tópico(s): Quinazolinone synthesis and applications
2021 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Produção Nacional
Revisado por pares
Lukas F. K. Kuderna, Jacob C. Ulirsch, Sabrina Mohd Rashid, Mohamed Ameen, Laksshman Sundaram, Glenn Hickey, Anthony J. Cox, Hong Gao, Arvind Kumar, François Aguet, Matthew J. Christmas, Hiram Clawson, Maximilian Haeussler, Mareike C. Janiak, Martin Kuhlwilm, Joseph D. Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rouselle, Felipe Ennes Silva, Lídia Águeda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R. Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S. Chuma, Julie E. Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G. Schraiber, Fabiano Rodrigues de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Pires Farias, João Valsecchi, Malu Messias, Maria Nazareth Ferreira da Silva, Mihir Trivedi, Rogério Vieira Rossi, Tomas Hrbek, Nicole Andriaholinirina, C. Rabarivola, Alphonse Zaramody, Clifford J. Jolly, Jane E. Phillips‐Conroy, Gregory K. Wilkerson, Christian R. Abee, Joe H. Simmons, Eduardo Fernández‐Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dong‐Dong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D. Keyyu, Sascha Knauf, Minh Đức Lê, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C. Kitchener, Dietmar Zinner, Marta Gut, Amanda Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M. D. Beck, Ioannis Karakikes, Ke Wang, Govindhaswamy Umapathy, Christian Roos, Jean P. Boubli, Adam Siepel, Anshul Kundaje, Benedict Paten, Kerstin Lindblad‐Toh, Jeffrey Rogers, Tomás Marquès‐Bonet, Kyle Kai‐How Farh,
Abstract Noncoding DNA is central to our understanding of human gene regulation and complex diseases 1,2 , and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome 3–9 . Identifying the genomic elements that have become constrained specifically in primates has been hampered by the faster evolution of noncoding DNA compared to protein-coding DNA 10 , the relatively short timescales separating primate species 11 , and the ...
Tópico(s): RNA Research and Splicing
2023 - Nature Portfolio | Nature
Produção Nacional
Revisado por pares
Lukas F. K. Kuderna, Hong Gao, Mareike C. Janiak, Martin Kuhlwilm, Joseph D. Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lídia Águeda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R. Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idrissa S. Chuma, Julie E. Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G. Schraiber, Fabiano Rodrigues de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Pires Farias, João Valsecchi, Malu Messias, Maria Nazareth Ferreira da Silva, Mihir Trivedi, Rogério Vieira Rossi, Tomas Hrbek, Nicole Andriaholinirina, C. Rabarivola, Alphonse Zaramody, Clifford J. Jolly, Jane E. Phillips‐Conroy, Gregory K. Wilkerson, Christian R. Abee, Joe H. Simmons, Eduardo Fernández‐Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dong‐Dong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D. Keyyu, Sascha Knauf, Minh Đức Lê, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C. Kitchener, Dietmar Zinner, Marta Gut, Amanda Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M. D. Beck, Govindhaswamy Umapathy, Christian Roos, Jean P. Boubli, Jeffrey Rogers, Kyle Kai‐How Farh, Tomás Marquès‐Bonet,
The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into long-standing questions in evolutionary and conservation biology and is urgent given severe threats these species are facing. Here, we present high-coverage whole-genome data from 233 primate species representing 86% of genera and all 16 families. This ...
Tópico(s): Chromosomal and Genetic Variations
2023 - American Association for the Advancement of Science | Science
Produção Nacional
Revisado por pares
Larissa Rodrigues Souto, Malu Siqueira Borges, Alexandre Márcio Marcolino, Fábio Viadanna Serrão, Roberta de Fátima Carreira Moreira,
Introduction Patellofemoral pain (PFP) is a chronic condition that affects up to 25% of the general population and has a negative impact on functionality and quality of life due to the high levels of pain experienced by these patients. In order to improve pain and function, rehabilitation programmes that combine adjunctive treatments with exercise therapy are often used in research and clinical settings. However, despite the variety of adjunctive treatments available, their effectiveness when compared ...
Tópico(s): Sports Performance and Training
2022 - BMJ | BMJ Open
Produção Nacional
Revisado por pares
Walessa Alana Bragança Aragão, Natacha Malu Miranda da Costa, Nathália Carolina Fernandes Fagundes, M. C. F. Silva, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro, Lílian Lund Amado, Maria Elena Crespo‐López, Cristiane do Socorro Ferraz Maia, Rafael Rodrigues Lima,
Mercury exposure is considered to be a public health problem due to the generation of toxic effects on human health as a result of environmental and occupational conditions.
Tópico(s): Selenium in Biological Systems
2017 - Oxford University Press | Metallomics
Maria Elizabeth de Sousa Rodrigues, Madelyn C. Houser, Douglas I. Walker, Dean P. Jones, Jianjun Chang, Christopher J. Barnum, Malú G. Tansey,
Abstract Background Insulin impairment and inflammation are two features common to type 2 diabetes and Alzheimer’s disease; however, the molecular and signaling interactions underlying this relationship are not well understood. Mounting evidence point to the associations between the disruption of metabolite processing in insulin impairment and neurodegenerative conditions such as Alzheimer’s. Although the brain depends partially on metabolites processed in the periphery, to date, little is known ...
Tópico(s): Regulation of Appetite and Obesity
2019 - BioMed Central | Alzheimer s Research & Therapy
Leandro Pellenz, Afonso Henrique da Silva Júnior, Carlos Rafael Silva de Oliveira, Luciana Prazeres Mazur, Lucía Helena Innocentini Mei, Núbia Malú Medeiros Rodrigues, Antônio Augusto Ulson de Souza, Adriano da Silva,
Tópico(s): Adsorption and biosorption for pollutant removal
2025 - Springer Science+Business Media | International Journal of Environmental Science and Technology
Produção Nacional
Revisado por pares
Bruna Raphaela Oliveira Silva, Wellington Francisco Rodrigues, Daniela Gomes Pires Abadia, Djalma A. Alves da Silva, Leonardo E. Andrade e Silva, Chamberttan Souza Desidério, Thaís Soares Farnesi-de-Assunção, Juliana Cristina Costa-Madeira, Rafaela Miranda Barbosa, Anna Victória Bernardes e Borges, Andrezza Cristina Cancian Hortolani, Loren Queli Pereira, Fernanda Rodrígues Helmo, Marcela Rezende Lemes, Laís Milagres Barbosa, Rafael Obata Trevisan, Malú Mateus Santos Obata, Giovanna F. Bueno, Fabiano Vilela Mundim, Ana Carolina de Morais Oliveira-Scussel, Ivan Borges Monteiro, Yulsef M. Ferreira, Guilherme H. Machado, Kennio Ferreira‐Paim, Hélio Moraes‐Souza, Marcos Silva, Virmondes Rodrigues, Carlo José Freire Oliveira,
COVID-19, also known as coronavirus disease 2019, is an infectious viral disease caused by SARS-CoV-2, a novel coronavirus. Since its emergence, its epidemiology has been explored; however, for some regions of the world, COVID-19’s behavior, incidence, and impact remain unclear. In continental nations like Brazil, this lack of knowledge results in nonuniform control, prevention, and treatment measures, which can be controversial in some locations. This study aimed to describe the epidemiological ...
Tópico(s): Long-Term Effects of COVID-19
2022 - Frontiers Media | Frontiers in Cellular and Infection Microbiology
Produção Nacional
Revisado por pares
Emília de Freitas Beirigo, Pablo Igor Ribeiro Franco, José Rodrigues do Carmo Neto, Rhanoica Oliveira Guerra, Thaís Farnesi Soares de Assunção, Isabella de Oliveira Ferrato de Sousa, Malú Mateus Santos Obata, Wellington Francisco Rodrigues, Juliana Reis Machado, Marcos Silva,
Infectious diseases are a major health concern worldwide, especially as they are one of the main causes of mortality in underdeveloped and developing countries. Those that are considered emerging and re-emerging are characterized by unpredictability, high morbidity and mortality, exponential spread, and substantial social impact. These characteristics highlight the need to create an "on demand" control method, with rapid development, large-scale production, and wide distribution. In view of this, ...
Tópico(s): Viral gastroenteritis research and epidemiology
2023 - Elsevier BV | Microbial Pathogenesis
Laura M. Butkovich, Madelyn C. Houser, Termpanit Chalermpalanupap, Kirsten A. Porter‐Stransky, Alexa F. Iannitelli, Jake Boles, Grace M. Lloyd, Alexandra S. Coomes, Lori N. Eidson, Maria Elizabeth de Sousa Rodrigues, Danielle Oliver, Sean D. Kelly, Jianjun Chang, Nora Bengoa‐Vergniory, Richard Wade‐Martins, Benoit I. Giasson, Valerie Joers, David Weinshenker, Malú G. Tansey,
Degeneration of locus Coeruleus (LC) neurons and dysregulation of noradrenergic signaling are ubiquitous features of Parkinson9s disease (PD). The LC is among the first brain regions affected by α-synuclein (asyn) pathology, yet how asyn affects these neurons remains unclear. LC-derived norepinephrine (NE) can stimulate neuroprotective mechanisms and modulate immune cells, while dysregulation of NE neurotransmission may exacerbate disease progression, particularly nonmotor symptoms, and contribute to ...
Tópico(s): Nerve injury and regeneration
2020 - Society for Neuroscience | Journal of Neuroscience
Produção Nacional
Revisado por pares
Bruna Lorena Meneses Marques, Thaís Souza Passos, Adrian Vinícius de Carvalho Dantas, Malu Andrade Alves de Lima, Susana Moreira, Victor M. Rodrigues, Marina Rocha do Nascimento Dantas, Patrícia Santos Lopes, A. Gomes, Rafael da Silva Fernandes, Francisco Humberto Xavier Júnior, Francisco Canindé de Sousa Júnior, Cristiane Fernandes de Assis,
Tópico(s): Fatty Acid Research and Health
2024 - Elsevier BV | Food Research International
Produção Nacional
Revisado por pares
Maria Elizabeth de Sousa Rodrigues, Mandakh Bekhbat, Madelyn C. Houser, Jianjun Chang, Douglas I. Walker, Dean P. Jones, Claudia Maria Penha Oller do Nascimento, Christopher J. Barnum, Malú G. Tansey,
The mechanisms underlying the association between chronic psychological stress, development of metabolic syndrome (MetS), and behavioral impairment in obesity are poorly understood. The aim of the present study was to assess the effects of mild chronic psychological stress on metabolic, inflammatory, and behavioral profiles in a mouse model of diet-induced obesity. We hypothesized that (1) high-fat high-fructose diet (HFHF) and psychological stress would synergize to mediate the impact of inflammation ...
Tópico(s): Diet, Metabolism, and Disease
2016 - Elsevier BV | Brain Behavior and Immunity
Lori N. Eidson, Maria Elizabeth deSousa Rodrigues, Michelle A. Johnson, Christopher J. Barnum, Billie Jeanne Duke, Yuan Yang, Jianjun Chang, Sean D. Kelly, M. Wildner, Raymond J. Tesi, Malú G. Tansey,
Physical and psychosocial maltreatment experienced before the age of 18, termed early life adversity (ELA), affects an estimated 39% of the world’s population, and has long-term detrimental health and psychological outcomes. While adult phenotypes vary following ELA, inflammation and altered stress responsivity are pervasive. Cytokines, most notably tumor necrosis factor (TNF), are elevated in adults with a history of ELA. While soluble TNF (solTNF) drives chronic inflammatory disease, transmembrane ...
Tópico(s): Neuroendocrine regulation and behavior
2019 - Elsevier BV | Brain Behavior and Immunity
Produção Nacional
Revisado por pares
Malu Barbosa, Artur Rodrigues Ferreira, Ricardo Lima Coelho, Pamela Carvalho Muniz, Camila Brambilla Souza, José Ap. Tristão Neto, Fanny Cascelli, Matheus Costa e Silva, Renata D’Alpino Peixoto,
e18638 Background: The American Society of Clinical Oncology (ASCO) and the European Society of Medical Oncology (ESMO) annual meetings as well as their GI dedicated meetings (ASCO GI and ESMO GI) have the premise to accept abstracts for oral presentations that have not been previously presented. Methods: We conducted a review of all 220 abstracts involving phase II or III trials of systemic therapies that have been presented orally from June 2019 to January 2023 at ASCO, ASCO GI, ESMO and ESMO GI ...
Tópico(s): Cancer Genomics and Diagnostics
2023 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Fernando do Amaral Nogueira, Malu Villela, Elisa Rodrigues Alves Larroudé,
A ComBio Energia – certificada como Empresa B – vende serviços de geração de vapor para indústrias. Para tanto, usa como combustível resíduos de biomassa, gerando economia e diminuindo impacto ambiental. Sua operação no Pará contempla expandir o uso de caroço de açaí como fonte de biomassa, com duas possibilidades de fornecedores: indústrias de médio porte ou batedores de açaí – pequenos comerciantes que fazem descarte incorreto desse resíduo. Para decidir, a ComBio precisa equilibrar desafios logísticos, ...
Tópico(s): Agricultural and Food Sciences
2021 - | Revista Brasileira de Casos de Ensino em Administração
Fernando do Amaral Nogueira, Malu Villela, Elisa Rodrigues Alves Larroudé,
Tópico(s): Social and Economic Solidarity
2021 - | Revista Brasileira de Casos de Ensino em Administração
Produção Nacional
Revisado por pares
Juciano Gasparotto, Paloma Rodrigues Chaves, Kátia da Boit Martinello, Helen Taís da Rosa, Rafael Calixto Bortolin, Luís F.O. Silva, Thallita Kelly Rabelo, Juliana da Silva, Fernanda Rabaioli da Silva, Adriane Perachi Nordin, Karina Biaggio Soares, Malu Siqueira Borges, Daniel Pens Gelain, José Cláudio Fonseca Moreira,
Obesity is an important nutritional disorder worldwide. Its association with environmental pollution may trigger an increase in oxidative stress and inflammatory parameters. Coal is a resource used throughout the world as an important fuel source for generating electricity. The ashes released by the coal combustion cause serious problems for human health due to their high toxicity and their capacity to bioaccumulate. The aim of this work was to investigate the effects of coal dust inhalation in ...
Tópico(s): Heavy Metal Exposure and Toxicity
2018 - Elsevier BV | Ecotoxicology and Environmental Safety
Produção Nacional
Revisado por pares
Natacha Malu Miranda da Costa, Russell Santiago Correa, Ismael Júnior, Adilson Figueiredo, Kelly Vilhena, Paulo Mecenas, Francisco Bruno Teixeira, Nayana Ferreira, João B. Pereira, Kelly das Graças Fernandes Dantas, Marcia Silva, Ademir Ferreira da Silva-Júnior, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro, Rafael Rodrigues Lima,
Aluminum absorption leads to deposits in several tissues. In this study, we have investigated, to our knowledge for the first time, aluminum deposition in the salivary glands in addition to the resultant cellular changes in the parotid and submandibular salivary glands in a model of chronic intoxication with aluminum citrate in rats. Aluminum deposits were observed in the parotid and submandibular glands. Immunohistochemical evaluation of cytokeratin-18 revealed a decreased expression in the parotid ...
Tópico(s): Heavy Metal Exposure and Toxicity
2014 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Kathryn P. MacPherson, Lori N. Eidson, Madelyn C. Houser, Blaine E. Weiss, Jenna L. Gollihue, Mary K. Herrick, Maria Elizabeth de Sousa Rodrigues, Lindsey Sniffen, Erica M. Weekman, Adam M. Hamilton, Sean D. Kelly, Danielle Oliver, Yuan Yang, Jianjun Chang, Timothy R. Sampson, Christopher M. Norris, Malú G. Tansey,
Introduction: Increasing evidence indicates that neurodegenerative diseases, including Alzheimer’s disease (AD), are a product of gene-by-environment interplay. The immune system is a major contributor mediating these interactions. Signaling between peripheral immune cells and those within the microvasculature and meninges of the central nervous system (CNS), at the blood-brain barrier, and in the gut likely plays an important role in AD. The cytokine tumor necrosis factor (TNF) is elevated in AD patients, ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2023 - Frontiers Media | Frontiers in Cellular Neuroscience
Produção Nacional
Revisado por pares
Gabriela de Oliveira Carvalho, Jaqueline Santos Silva, Franciele Marques Vanderlei, Jéssica Kirsch Michelleti, Aryane Flauzino Machado, Aline Castilho de Almeida, Ítalo Ribeiro Lemes, Malu Siqueira Borges, Larissa Rodrigues Souto, Jayme Netto, Carlos Marcelo Pastre,
Introdução: A Imersão em água fria (IAF) ganha destaque no cenário da recuperação pós-esforço.Nesse contexto, o efeito placebo deve ser estudado para melhor entendimento da técnica.Objetivos: Analisar e comparar os efeitos da IAF quando aplicada de forma sistemática, com a condição placebo na variável creatina quinase (CK).Métodos: A amostra foi de 10 atletas de alto rendimento do sexo masculino, alocados de forma randomizada: grupo placebo (GP) e grupo intervenção recuperativa (GE).Quatro vezes na ...
Tópico(s): Agricultural and Food Sciences
2016 - UNIVERSIDADE DO OESTE PAULISTA | Colloquium Vitae