Manuel J. Antunes, Manuel Pedro Magalhães, Peter R. Colsen, Robin H. Kinsley,
January 1981 through February 1985, 241 patients with rheumatic mitral valve disease (mean age 21.5 ± 11.8 years) were subjected to comprehensive mitral valvuloplasty. One hundred seven patients (44.4%) were 15 years or younger and 63 (26.1%) were 12 years or younger. One hundred seventy five patients had pure or predominant regurgitation (mean age 19.3 ± 10.7 years) and 40 (16.6%) had active rheumatic carditis at the time of the operation. Almost all patients (229) were in New York Heart Association Functional ...
Tópico(s): Cardiac Structural Anomalies and Repair
1987 - Elsevier BV | Journal of Thoracic and Cardiovascular Surgery
Manuel J. Antunes, Manuel Pedro Magalhães,
The operative results of 249 mitral valvular reoperations performed in 215 patients from 1974 through 1986 were reviewed to identify groups at greater risk. Two to 4 reoperations were performed in 28 patients. The mean interval between the first and second valve procedures was 47 ± 40 months. The most common indications for reoperation were degeneration of bioprostheses (44%) and thrombosis of mechanical prostheses (26%). Thirty patients (12%) died. This rate was significantly higher (p < 0.02) than that ...
Tópico(s): Cardiac pacing and defibrillation studies
1987 - Elsevier BV | The American Journal of Cardiology
David Prieto‐Merino, Pedro E. Antunes, Manuel J. Antunes,
For many patients suffering from end-stage heart failure, heart transplantation remains the only hope for survival, but the shortage of donor organ is increasing. The growing number of patients awaiting heart transplantation has led many centers to expand the donor pool by liberalizing donor criteria, including advances in surgical techniques on the donor heart, such as valve repair. We subjected 4 donor hearts to bench repair of the mitral valve. The first heart was from a 35-year-old woman whose ...
Tópico(s): Cardiac Structural Anomalies and Repair
2009 - Elsevier BV | Transplantation Proceedings
Gonçalo F. Coutinho, V. Bihun, Pedro Correia, Pedro E. Antunes, Manuel J. Antunes,
The importance of preservation of the subvalvular apparatus (PSVA) during mitral valve replacement (MVR) in non-rheumatic mitral valves is well recognized. Our aim was to analyse the impact of PSVA in MVR for rheumatic valves on long-term survival. From January 1992 to December 2012, 605 consecutive patients with rheumatic mitral valve disease were submitted to MVR. PSVA (limited to the posterior leaflet) was achieved in 224 (37.7%) patients. Follow-up was 4259 patient-years, and complete for 97% of ...
Tópico(s): Cardiac Structural Anomalies and Repair
2015 - Oxford University Press | European Journal of Cardio-Thoracic Surgery
Marco Baptista, Fernando Antunes, Manuel Souteiro Gonçalves, Bernard Morvan, Ana Silveira,
This study focuses on the investigation of the kinetics of municipal solid waste composting in three full-scale mechanical-biological treatment (MBT) plants. The aims were to test a kinetic model based on volatile solids (VS) content change for describing the composting process in MBT plants, and to identify the model parameters that affected the estimation of the reaction rate constant most. To achieve this, VS content and several environmental conditions, namely temperature, moisture content, oxygen ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2010 - Elsevier BV | Waste Management
Flora M. Antunes, Manuel S. Malmierca,
An animal's survival may depend on detecting new events or objects in its environment, and it is likely that the brain has evolved specific mechanisms to detect such changes. In sensory systems, neurons often exhibit stimulus-specific adaptation (SSA) whereby they adapt to frequently occurring stimuli, but resume firing when “surprised” by rare or new ones. In the auditory system, SSA has been identified in the midbrain, thalamus, and auditory cortex (AC). It has been proposed that the SSA observed ...
Tópico(s): Neuroscience and Neuropharmacology Research
2011 - Society for Neuroscience | Journal of Neuroscience
Adeniyi S. Ogunlaja, Wadzanai Chidawanyika, Edith Antunes, Manuel A. Fernandes, Tebello Nyokong, Nelson Torto, Zenixole R. Tshentu,
The reaction between [VIVOSO4] and the tetradentate N2O2-donor Schiff base ligand, N,N-bis(o-hydroxybenzaldehyde)phenylenediamine (sal-HBPD), obtained by the condensation of salicylaldehyde and o-phenylenediamine in a molar ratio of 2 : 1 respectively, resulted in the formation of [VIVO(sal-HBPD)]. The molecular structure of [VIVO(sal-HBPD)] was determined by single crystal X-ray diffraction, and confirmed the distorted square pyramidal geometry of the complex with the N2O2 binding mode of the tetradentate ...
Tópico(s): Polyoxometalates: Synthesis and Applications
2012 - Royal Society of Chemistry | Dalton Transactions
Jorge Ambrósio, J. Pombo, Pedro Antunes, Manuel Pereira,
The pantograph–catenary dynamic interaction analysis program (PantoCat) addresses the need for a dynamic analysis code able to analyse models of the complete overhead energy collecting systems that include all mechanical details of the pantographs and the complete topology and structural details of the catenary. PantoCat is a code based on the finite element method, for the catenary, and multibody dynamics methods, for the pantograph, integrated via a co-simulation procedure. A contact model based ...
Tópico(s): Vibration and Dynamic Analysis
2014 - Taylor & Francis | Vehicle System Dynamics
Flora M. Antunes, Manuel S. Malmierca,
Tópico(s): Hearing Loss and Rehabilitation
2013 - Springer Science+Business Media | Brain Topography
Paulo Vitória, José Cunha Machado, Ana Carolina Araújo, Sofía Ravara, Catarina Samorinha, Henedina Antunes, Manuel Rosas, Elisardo Becoña, José Precioso,
Second-hand tobacco smoke (SHS) is a major indoor pollutant that causes serious health problems for all exposed, especially children. Children are often exposed to SHS at home, due to parental or other households' or guests' smoking. This study describes Portuguese children's exposure to SHS at home (total and by Portuguese main regions). In 2010/2011, a questionnaire was applied to a sample of Portuguese children in the 4th grade (N = 3187, mean age 9.05 ± 0.7 years, 51.1% male). Descriptive analysis, ...
Tópico(s): Air Quality and Health Impacts
2015 - Elsevier BV | Revista Portuguesa de Pneumologia
L. Ferreira, A.C. Moniz, Ana Carneiro, Ana Miranda, C. Fangueiro, D. Fernandes, Isabel Silva, I. Palhinhas, Jane de Lemos, José Leopoldo Ferreira Antunes, Manuel M. Cardoso Leal, Neuza Maria Vilar Sampaio, Sara Faria,
To investigate the influence of glycemic variability (GV) on length of stay and in-hospital mortality in non-critical diabetic patients. A observation retrospective study was performed. Diabetic patients admitted between January and June 2016 with the diagnosis of community-acquire pneumonia (CAP) and/or acute exacerbation of chronic obstructive pulmonary disease (COPD) were enrolled and glycemic control (persistent hyperglycemia, hypoglycemia, mean glucose level (MGL) and respective standard deviation ( ...
Tópico(s): Diabetes and associated disorders
2018 - Elsevier BV | Diabetes & Metabolic Syndrome Clinical Research & Reviews
Mafalda Correia, Vânia Constâncio, Joana Cruz Silva, Pedro Lima, Mario E. Moreira, Luís Antunes, Manuel Fonseca,
BackgroundOn March 2020, the World Health Organization declared the coronavirus disease 2019 outbreak a pandemic. During this period, surgical activity and admission to the Emergency Department (ED) decreased globally. The aim of this article is to understand how the admission of a patient to the ED for vascular surgery changed in our center in Portugal and if this situation prevented urgent surgical procedures.MethodsThrough a retrospective study, we compared the volume of patients admitted to the ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2020 - Elsevier BV | Annals of Vascular Surgery
Sara Ferreira, Mário Antunes, Manuel E. Correia,
Tampered multimedia content is being increasingly used in a broad range of cybercrime activities. The spread of fake news, misinformation, digital kidnapping, and ransomware-related crimes are amongst the most recurrent crimes in which manipulated digital photos and videos are the perpetrating and disseminating medium. Criminal investigation has been challenged in applying machine learning techniques to automatically distinguish between fake and genuine seized photos and videos. Despite the pertinent ...
Tópico(s): Anomaly Detection Techniques and Applications
2021 - Multidisciplinary Digital Publishing Institute | Journal of Imaging
Flora M. Antunes, Manuel S. Malmierca,
The corticothalamic (CT) pathways emanate from either Layer 5 (L5) or 6 (L6) of the neocortex and largely outnumber the ascending, thalamocortical pathways. The CT pathways provide the anatomical foundations for an intricate, bidirectional communication between thalamus and cortex. They act as dynamic circuits of information transfer with the ability to modulate or even drive the response properties of target neurons at each synaptic node of the circuit. L6 CT feedback pathways enable the cortex to ...
Tópico(s): Functional Brain Connectivity Studies
2021 - Frontiers Media | Frontiers in Neural Circuits
Maria João Correia, António B. Pimpão, D. Fernandes, Judit Morelló, Catarina O. Sequeira, Joaquim Calado, Alexandra M. M. Antunes, Manuel Almeida, Patrícia Branco, Emília C. Monteiro, João B. Vicente, Jacinta Serpa, Sofia A. Pereira,
In this review encouraged by original data, we first provided in vivo evidence that the kidney, comparative to the liver or brain, is an organ particularly rich in cysteine. In the kidney, the total availability of cysteine was higher in cortex tissue than in the medulla and distributed in free reduced, free oxidized and protein-bound fractions (in descending order). Next, we provided a comprehensive integrated review on the evidence that supports the reliance on cysteine of the kidney beyond cysteine ...
Tópico(s): Biomedical Research and Pathophysiology
2022 - Multidisciplinary Digital Publishing Institute | Molecules
José Barateiro, Gonçalo Antunes, Manuel Cabral, José Borbinha, Rodrigo Rodrigues,
Digital preservation aims at maintaining digital objects and data accessible over long periods of time. Data grids provide several functionalities required by digital preservation systems, especially when massive amounts of data must be preserved, as in e-Science domains. We propose the use of existing data grid solutions to build frameworks for digital preservation. In this paper we survey the main threats to digital preservation, which are used to identify a central point of failure in the metadata ...
Tópico(s): Scientific Computing and Data Management
2008 - Springer Science+Business Media | Lecture notes in computer science
Joana Saraiva, Pedro E. Antunes, Manuel J. Antunes,
OBJECTIVES: To analyse perioperative results, long-term survival and freedom from complications after coronary artery bypass grafting (CABG) in young adults. METHODS: A total of 163 patients, 40 years old or younger, had isolated CABG from January 1989 to December 2010. Pre- and perioperative demographic and clinical data were retrieved from a prospectively organised database. Follow-up data were obtained by letter or telephone interviews. The mean age of the patients was 37.6 ± 2.9 years and 146 were ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2017 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery
Sara Ferreira, Mário Antunes, Manuel E. Correia,
Deepfake and manipulated digital photos and videos are being increasingly used in a myriad of cybercrimes. Ransomware, the dissemination of fake news, and digital kidnapping-related crimes are the most recurrent, in which tampered multimedia content has been the primordial disseminating vehicle. Digital forensic analysis tools are being widely used by criminal investigations to automate the identification of digital evidence in seized electronic equipment. The number of files to be processed and ...
Tópico(s): Advanced Steganography and Watermarking Techniques
2021 - Multidisciplinary Digital Publishing Institute | Data
Paulo Vitória, José Cunha Machado, Sofía Ravara, Ana Carolina Araújo, Catarina Samorinha, Henedina Antunes, Manuel Rosas, Elisardo Becoña, José Precioso,
To assess the prevalence of children's exposure to second-hand smoke in the family car; to compare exposure among children with smoking and non-smoking parents.In 2011, a self-administered questionnaire was applied to a 4th grade Portuguese children national sample (N=3187, mean age 9.5 ± 0.7, 51.1% boys). Prevalence rates and chi-square tests were computed.Of the participants, 52.0% reported having, at least, one smoking parent. Overall exposure in the car was 28.9% (95% CI 27.3-30.5). Children's exposure ...
Tópico(s): School Health and Nursing Education
2014 - Elsevier BV | Gaceta Sanitaria
Maria Leonor Neto, Marília Antunes, Manuel Lopes, Duarte M. S. Ferreira, James K. Rilling, Diana Prata,
Background: The neuropeptides oxytocin and vasopressin have been repeatedly implicated in social decision making by enhancing social salience and, generally, cooperation. The iterated and sequential version of the prisoner’s dilemma (PD) game is a social dilemma paradigm eliciting strategies of cooperation versus competition. Aims: We aimed to characterise the role of PD players’ sex, game partner type (computer vs. human) and oxytocin or vasopressin inhalation on the player’s strategy preference. ...
Tópico(s): Attachment and Relationship Dynamics
2020 - SAGE Publishing | Journal of Psychopharmacology
Gonçalo F. Coutinho, Rita Pancas, Pedro E. Antunes, Manuel J. Antunes,
We propose to analyse the long-term follow-up in patients older than 65 years of age who received a mechanical valve in the aortic position, using death and prosthetic-related complications as endpoints. From April 1988 to December 1995, 144 consecutive patients 65-75 years of age (mean 67.7+/-2.5) were enrolled. Total duration of follow-up was 1663 patient-years (median 13.0 years) and was complete for 99% of the patients. Thirty-day mortality was 1.4% (n=2). At the end of the study, 77 patients (53. ...
Tópico(s): Aortic Disease and Treatment Approaches
2009 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery
Helena Cristina Serrano, Cristina Antunes, Manuel J. Pinto, Cristina Máguas, Maria Amélia Martins‐Loução, Cristina Branquinho,
AimsThe Inclusive Niche Hypothesis has not been validated for plants using ecophysiological performance. The few experiments have measured growth and competition but not the physiological response of plants. A metallophyte plant that hyperaccumulates aluminium (Al), Plantago almogravensis, showed a defined spatial distribution by occurring mostly on vegetation gaps associated with metalliferous areas (geochemical islands). This case was used to determine, in situ, whether the Inclusive Niche Hypothesis ...
Tópico(s): Pasture and Agricultural Systems
2014 - Oxford University Press | Journal of Plant Ecology
Submitral left ventricular aneurysm is a widely recognized but relatively unknown entity that occurs almost exclusively in African patients and is often associated with mitral regurgitation. In the past 2 1/2 years, nine patients with submitral aneurysm were operated on by a new transatrial approach that exposes the neck of the aneurysm through an incision in the floor of the left atrium (roof of the aneurysm). There were four female and five male patients and the mean age was 28 +/- 3 years (range 23 ...
Tópico(s): Cardiac Valve Diseases and Treatments
1987 - Elsevier BV | Journal of Thoracic and Cardiovascular Surgery
Lars G. Svensson, Robert W. Stewart, Delos M. Cosgrove, Bruce W. Lytle, Manuel Antunes, Edwin G. Beven, Anthony J. Furlan, Alexandru Gottlieb, Daniel F. Grum, Ronald A. Hinder, Peter K. Schoenwald, Brenda S. Lewis, António J. Salgado, Floyd D. Loop,
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
1988 - Elsevier BV | Journal of Thoracic and Cardiovascular Surgery
Gilbert Habib, Bruno Hoen, Pilar Tornos, Franck Thuny, Bernard Prendergast, Isidre Vilacosta, Philippe Moreillon, Manuel Antunes, Ulf Thilén, John Lekakis, M Lengyel, Ludwig Müller, Christoph Naber, Petros Nihoyannopoulos, Anton Moritz, José Luis Zamorano,
El contenido de las Guías de Práctica Clínica de la Sociedad Europea de Cardiología (ESC) ha sido publicado para uso exclusivamente personal y educacional. No está autorizado su uso comercial. No se autoriza la traducción o reproducción en ningún formato de las Guías de la ESC ni de ninguna de sus partes sin un permiso escrito de la ESC. El permiso puede obtenerse enviando una solicitud por escrito a Oxford University Press, la empresa editorial del European Heart Journal y representante autorizada ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2009 - Elsevier BV | Revista Española de Cardiología
Gilbert Habib, Bruno Hoen, Pilar Tornos, Franck Thuny, Bernard Prendergast, Isidre Vilacosta, Philippe Moreillon, Manuel Antunes, Ulf Thilén, John Lekakis, M Lengyel, Ludwig Müller, Christoph Naber, Petros Nihoyannopoulos, Anton Moritz, José Luis Zamorano, M. O. Evseev,
Рациональная Фармакотерапия в
Tópico(s): Infective Endocarditis Diagnosis and Management
2010 - Stolichnaya Izdatelskaya Kompaniya | Rational Pharmacotherapy in Cardiology
Gilbert Habib, Bruno Hoen, Pilar Tornos, Franck Thuny, Bernard Prendergast, Isidre Vilacosta, Philippe Moreillon, Manuel Antunes, Ulf Thilén, John Lekakis, M Lengyel, Ludwig Müller, Christoph Naber, Petros Nihoyannopoulos, Anton Moritz, José Luis Zamorano, M. O. Evseev,
Рациональная Фармакотерапия в Кардиологии 2010;6(6) (Окончание.Начало в предыдущем номере) Оценка прогноза при поступлении в стационарГоспитальная летальность больных ИЭ варьируется от 9,6% до 26% [14,68,[96][97][98][99][100][101][102].Быстрое выделение пациентов, у которых имеется самый высокий риск смерти, позволяет изменить течение болезни и улучшить прогноз.Если ближайший прогноз крайне неблагоприятен, необходимы более тщательное наблюдение и более агрессивная стратегия лечения (например, неотложное ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2010 - Stolichnaya Izdatelskaya Kompaniya | Rational Pharmacotherapy in Cardiology
Sónia M. L. J. Rosa, Maria do Carmo Antunes-Madeira, Manuel Matos, Amália S. Jurado, Vı́tor M.C. Madeira,
Bacillus stearothermophilus, a useful model to evaluate membrane interactions of lipophilic drugs, adapts to the presence of amiodarone in the growth medium. Drug concentrations in the range of 1–2 μM depress growth and 3 μM completely suppresses growth. Adaptation to the presence of amiodarone is reflected in lipid composition changes either in the phospholipid classes or in the acyl chain moieties. Significant changes are observed at 2 μM and expressed by a decrease of phosphatidylethanolamine ( ...
Tópico(s): thermodynamics and calorimetric analyses
2000 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
João Manuel Antunes Bras, Chrystel Becker, S. Bourgoin, M. C. Lombard, F. Cesselin, M. Hamon, Michel Pohl,
The demonstration of preproenkephalin A gene expression in rat dorsal root ganglia has raised the question of the physiological role of met-enkephalin-containing primary afferent fibres. Recently, we showed that systemic infection with a recombinant Herpes simplex virus encoding preproenkephalin A (HSVLatEnk1) yielded a marked increase in the density of met-enkephalin-like material synthesising neurons in rat dorsal root ganglia. This study further investigated the synthesis, transport and release ...
Tópico(s): Adenosine and Purinergic Signaling
2001 - Elsevier BV | Neuroscience
Produção Nacional
Antônio Martinez Fandiño, Catarina Marques, Rui Menezes, Sónia R. Bentes,
... and Validation Antonio Martinez Fandiño, Catarina Maria Valente Antunes Marques, Rui Manuel Pereira de Menezes, Sónia Margarida Ricardo Bentes Abstract ...
Tópico(s): Job Satisfaction and Organizational Behavior
2015 - | Review of Contemporary Business Research