Limpar
937 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Primary Document Acesso aberto

Manuel De Jesus Troncoso De La Concha Presidente Del Senado,

Book.

1951 - Gale Group | World Scholar Latin America

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luciana Lamarão Damous, Juliana Sanajotti Nakamuta, Ana ET Saturi de Carvalho, Kátia Cândido Carvalho, José Maria Soares, Manuel de Jesus Simões, José Eduardo Krieger, Edmund Chada Baracat,

A major concern in ovarian transplants is substantial follicle loss during the initial period of hypoxia. Adipose tissue-derived stem cells (ASCs) have been employed to improve angiogenesis when injected into ischemic tissue. This study evaluated the safety and efficacy of adipose tissue-derived stem cells (ASCs) therapy in the freshly grafted ovaries 30 days after injection. Rat ASCs (rASCs) obtained from transgenic rats expressing green fluorescent protein (GFP)-(5 × 104 cells/ovary) were injected in ...

Tópico(s): Pluripotent Stem Cells Research

2015 - BioMed Central | Reproductive Biology and Endocrinology

Jornais Acesso aberto

From Peter Hazelhurst, By Michael Horsnell, , John Witherow, Richard Ford, By Clifford Webb Midlands Industrial Correspondent, By Frances Gibb, By George Clark Political Correspondent, From Robert Fisk, From Paul Routledge Labour Editor, By Fred Emery Political Editor, By a Staff Reporter, By Michael Baily Transport Correspondent, From Annabel Ferriman Health Services Correspondent, By Ian Bradley, By Edward Townsend, By Our Political Editor, From Our Correspondent, By John Roper, From Christopher Warman, By Hugh Clayton Agriculture Correspondent, By Nicholas Timmins, From Arthur Osman, By Henry Stanhope Defence Correspondent, By John Young Planning Reporter, From Our Education Correspondent, By Kenneth Gosling Arts Reporter, By Harry Golombek Chess Correspondent, By Pat Healy Social Services Correspondent, By Diana Geddes Education Correspondent, By Lucy Hodges, By Arthur Reed Air Correspondent, By Stanley Baldwin, From Patricia Clough, From David Wood, From Charles Hargrove, From Robert Schuil, From Patrick Brogan, By Hugh Noyes Parliamentary Correspondent, From Patrick Knight, by Arrigo Levi, From Christopher Walker, From Tewfik Mishlawi, From Michael Leapman, From Ivor Davis, From Hasan Akhtar, From Denis Reinhardt, Dessa Trevisan, From Richard Hughes, Michael Ratcliffe, Jacky Gillott, H. R. F. Keating, Michael Church, Ned Chaillet, Brian Martin, Nikolai Tolstoy, John Hackett, Jenny Woolf, Shona Crawford Poole, Hugh Clayton, John Higgins, John Percival, Joan Bakewell, Stanley Sadie, Barry Millington, Ronald Butt, Bernard Levin, Alan Hamilton, CARLOS BRAGA, , JOAOUIM JOSE, , BARBOSA ROMERO, , JULIO BARREIROS, MARTINS, , JOSE MANUEL VAZ, , CARLOS AUGUSTO, , G. MOURA BRANCO, , HERNANI LOPES, , da SILVA MALA, , L. CHAINHO, , PEREIRA, , L. de JESUS, SANTOS SOARES, , S. SANTOS, , JOAO PINHEIRO, , C. A. A. BERNARDO, , JOAO FERREIRA, , MARIA ISABEL, CALADO FERREIRA, , VIRGINIA M. GERGORIO, , EDITE M. G. P. FERNANDES, , JOSE MANUEL E. VALENCA, , MARIA RAQUEL VALENCA, , RAUL VIDAL, MARIO de ARAUJO, , REX DAVIS, , T. A. BIRRELL, , HUGH PESKETT, , W. E. BAUGH, , IAIN MONCREIFFE OF THAT ILK, , W. H. HANKIN, , ANTONY WHITAKER, , A. L. S. CORNER, , RICHARD RITGHIE, , TITO BENADY, , KENNET, , NOEL ANNAN, , MICHAEL HOLROYD, , DAVID GARNETT, , VICTOR PRITCHETT, , EVAN LUARD, , D. R. MIDGLEY, , ADRIAN C. BOULT, , GERTRUDE M. BANNISTER, , By the Staff of Nature, From Our Own Correspondent, By Geraldine Norman Sale Room Correspondent, By Clifford Longley Religious Affairs Correspondent, Cyril Bainbridge, By our Arts Reporter, W. W. W. and J. B. write:, Baroness Airey of Abingdon writes:, By Mitchell Platts, By Keith Macklin, By John Nicholls, John Young, From Richard Streeton, By John Woodcock Cricket Correspondent, By Michael Seely, By Norman Fox Football Correspondent, By Our Rifle Shooting Correspondent, By Pamela Macgregor-Morris, By John Watson, By Peter Hill Industrial Editor, By David Felton Labour Reporter, By Roman Eisenstein Banking Correspondent, By John Whitmore Financial Correspondent, By Tim Jones, From Michael Hornsby, By Peter Wilson-Smith, From Frank Vogl, William Olsen, By Kenneth Owen Technology Editor, By Bill Johnstone, By Margaret Stone, By Nicholas Hirst Energy Correspondent, MELVILLE BERNSTEIN, , MRS M. D. LOVEDAY, , JOHN GADD, , A. C. PARSONS, , J. B. DANEL, , HUGH CAWDRON, , BY THE FINANCIAL EDITOR, Ross Davies, David Blake, Derek Harris, Michael Prest Mining correspondent, By Our Financial Staff, By Rosemary Unsworth, Peter Davalle,

News: EEC budget is approved seven months late, Latest pamphlets Religious beliefs of Elgar, The Times Cook Separate ways with eggs, Kidnap victim is ...

1980 - Gale Group | TDA

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luciana Lamarão Damous, Juliana Sanajotti Nakamuta, Ana Elisa Teófilo Saturi de Carvalho, José Maria Soares, Manuel de Jesus Simões, José Eduardo Krieger, Edmund Chada Baracat,

The preliminary results of ovarian transplantation in clinical practice are encouraging. However, the follicular depletion caused by ischemic injury is a main concern and is directly related to short-term graft survival. Cell therapy with adipose tissue-derived stem cells (ASCs) could be an alternative to induce early angiogenesis in the graft. This study aimed to evaluate ASCs therapy in rat cryopreserved ovarian grafts. A single dose of rat ASC (rASCs) or vehicle was injected into the bilateral ...

Tópico(s): Pluripotent Stem Cells Research

2015 - BioMed Central | Stem Cell Research & Therapy

Jornais Acesso aberto

Roger Bannister, Gráinne Gilmore, Giles Smith, Matt Dickinson Chief Sports Correspondent, kylie Minogue, Janice Turner, Andrew Robson, John McNamara, Matthew Syed, Barry Forshaw, David Brown, David Canter, Alexandra Frean, Val McDermid, Alice Bowe, Sarah Kent, Carol Anne Davis, Frances Gibb Legal Editor, Roy Procter, Simon Barnes, Amanda Ursell, Jane MacQuitty, Fred R. Shapiro Editor, Ashling O'Connor Olympics Correspondent, Peter Lansley, Jenny Agutter, Simon Hills, Robert Lindsay, Paul Hoggart, Mark Souster, Catherine Boyle, Richard Hobson, John Mulvey, Jane Knight, Ivo Tennant, Sarah Urwin Jones, Alexandra Frean Education Editor, Tony Turnbull, Emma Cook, Philip Howard, Julia Brookes, Carol Midgley, David Lister Scotland Correspondent, Christine Seib, Michael O'connell, David Chater, Kate Wighton, James Bone, James Ducker, Melissa Katsoulis, Rachel Campbell-Johnston, Clive Davis, Annie Gatti, Richard Hobson One-Day Cricket Correspondent, Kate Reardon, S. Bell, Gabrielle Starkey, Kevin Crowley, Gráinne Gilmore Economics Correspondent, Will Pavia, Graham Stewart, Bob Stanley, Wendy Ide, James Hider, John Bungey, Kevin Eason, Andrew Norfolk, Giles Coren, Vivienne Parry, Caroline Hendrie, Martin Fletcher, Sathnam Sanghera, Dr Copperfield, Cecilia Hatt, Pat Gibson, Valerie Elliott Countryside Editor, Nancy Durrant, Hilary Rose, Vinny Lee, Siobhan Kennedy, Francis Elliott, Barry Norman, Richard Hollis, Kim Lavely Chief Executive, Jack Malvern, Dominic Walsh, Steve Bird, Tom Bawden, Guy Clapperton, Ruth Corbett, Debra Craine, Nigel Williams, Joe Cushnan, Margie Ambrose, John Sutherland, Allan Simmons, Peter Stiff, Tom Charity, Jill Dupleix, Daniel Finkelstein, Laura Lovett, Lyn Thomas, Simon Collins, Dr Naomi Mansfield, Jo Morris, Alan Hamilton, Emma Lunn, Stuart McGurk, Ronald Knox, Sophie Harris, Ian Belcher, Ed McBain, Mo Hayder, Charlie Higson, Tina Gaudoin, Robin Pagnamenta Environment Editor, David Hands, Charles Bremner, Josephine Tey, Jamie Walker, Ron Lewis, Ben MacHell, Lucy Sweeney, David Charter, Susan Thompson, Mary Branscombe, Derwent May, William Drew, Tim Teeman, Kate Muir, Louise Welsh, Aggie MacKenzie, Russell Kempson, Tom Whitwell, Simon Midgley, Emma Klein, Gary Duncan Economics Editor, Edward Fennell, Jonathan Burge, Stephen Anderton, Ed Potton, Sarah Vine, Mark Atherton, Lisa Armstrong, John Westerby, Patrick Hosking Banking and Finance Editor, Ryan Phillippe, Jane Wheatley, Tom Baldwin, James Rossiter, Sam Coates, Pete Paphides, Sally Baker, David Robertson Business Correspondent, Rob Wright, Geoffrey Dean, Denise Van Outen, Naomi Shragai, John Cook Chairman, Raymond Keene, Ian Evans, Suzi Godson, Matthew Pryor, Matt Hughes, Gordon Ramsay, Kate Gray, Albert Kahn, Christine Buckley Industrial Editor, Sean O'Neill, Chris Partridge, Simon Barnes Chief sports writer, Francis Gilbert, Marcus Binney Architecture Correspondent, Christopher MacLehose, Roger Phillips, Rick Jones, Patricia Cornwell, Chris Campling, Jo Carlowe, Hilly Janes, Jill Sherman, Patrick Hosking, Richard Owen, Helen Nugent, Andrew Collins, Christopher Martin-Jenkins Chief Cricket Correspondent, Rebecca O'connor, Damian Whitworth, Professor David Thomas, Roger Boyes, Marcel Berlins, James Charles, Thomasina Miers, James Naughtie, David Hands Rugby Correspondent, Owen Slot Chief Sports Reporter, James Collard, Julian Muscat, Paul Simons, Kevin Maher, Nicholas Clee, Fiona Sims, Nigel Kendall, Gerard Baker US Editor, Ian Rankin, Dominic Kennedy, Joanna Pitman, Philip Webster Political Editor, Jonathan Clayton, Ronnie O'Sullivan, Michel Odent, Robert Crampton, Steve Hawkes, Keith Hopcroft, Richard Ehrlich, Harriet Addison, Dominic Maxwell, Sophie Heawood, Roderick Strange, Matthew Parris, Mark Bridge, Alicia Douvall, William Boyd, George Caulkin, Tim Wapshott, Caitlin Moran, Sheila Keating, Alan Lee, Celia Dodd, Kevin Dowling, George Cowie, Neil Fisher, Maurice Lawson, Ben MacIntyre, Jeremy Page South Asia Correspondent, Oliver Dowding, Ben Webster, Antonia Fraser, David Hutcheon, John Naish, Steven Berkoff, Mark Henderson, Chris Ayres, James Jackson, Patrick Foster, Alan Woodward, Nigel Hawkes Health Editor, George W. Bush, Anna Shepard, Louise Cohen, Bryce Elder Personal Investor, Benedict Nightingale, Dr Thomas Stuttaford, Derek Arthur, Stephen Dalton, Leo Lewis, Karin Slaughter, Russell Celyn Jones, Simon Kernick, Tom Chesshyre, Tony Halpin, Richard Morrison, James Christopher, David Budworth, Michael Evans, Alan Jackson, Jim Kelly, Kim Newman, Will Hide, Fiona Hamilton, David Robertson, Helen Mathers, Trevor Trotman, Richard Beeston Foreign Editor,

... Luxx Freezing eggs Alastair Campbell Riches of Russia José Mourinho The Workout Magazine Travel LeKnowledge Body&Soul ... 2008, aged 76 Lives online The resurrection of Jesus was real and physical Faith Unbearable lightness of ...

2008 - Gale Group | TDA

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luciana Lamarão Damous, Juliana Sanajotti Nakamuta, Ana Elisa Teófilo Saturi de Carvalho, Kátia Cândido Carvalho, José Maria Soares, Manuel de Jesus Simões, José Eduardo Krieger, Edmund Chada Baracat,

This study aimed to evaluate whether a gelatin-based Gelfoam sponge is feasible as a scaffold for adipose tissue-derived stem cell (ASC) therapy in rat frozen-thawed ovarian autografts.Two sets of studies were performed. The in vitro set evaluated ASCs' viability in the Gelfoam scaffold at different times of co-culturing (after 24, 48, 72, 96, and 120 h). The in vivo set used 20 12-week-old adult female Wistar rats. Frozen-thawed ovarian grafts were treated with ASCs delivered in Gelfoam scaffolds ...

Tópico(s): Tendon Structure and Treatment

2015 - Springer Science+Business Media | Journal of Assisted Reproduction and Genetics

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

I.C. Nogueira, L.S. Cavalcante, Paula F. S. Pereira, Mariana Marcielo de Jesus, José Manuel Rivas Mercury, Nouga Cardoso Batista, Máximo Siu Li, E. Longo,

In this article, the structural refinement, morphology and optical properties of barium strontium molybdate [(Ba 1− x Sr x )MoO 4 with x = 0, 0.25, 0.50, 0.75 and 1] crystals, synthesized by the co-precipitation (drop-by-drop) method, are reported. The crystals obtained were structurally characterized by X-ray diffraction (XRD), Rietveld refinement, and Fourier transform–Raman (FT–Raman) and Fourier transform–infrared (FT–IR) spectroscopies. The shapes of the crystals were observed by means of field-emission ...

Tópico(s): Advanced Condensed Matter Physics

2013 - Wiley | Journal of Applied Crystallography

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Edilson Silva Machado, Renata Leite, Cíntia Cichowski dos Santos, Geórgia Lazzari Artuso, Fernando Gluszczak, Leonardo Giovani de Jesus, José Manuel Peixoto Caldas, Markus Bredemeier,

To describe and analyze a new protocol for the extraction of platelet-rich plasma (PRP) for use in clinical practice and compare this technique with methods that have been previously described in the medical literature.We extracted PRP from 20 volunteers using four different protocols (single spin at 1600 ×g, single spin at 600 ×g, double spin at 300 and 700 ×g, and double spin at 600 and 900 ×g). In another group of 12 individuals, we extracted PRP with our new technique (named 'turn down-turn up') consisting ...

Tópico(s): Genital Health and Disease

2019 - Elsevier BV | Clinics

Artigo Acesso aberto Revisado por pares

Jean François Uhl, Albert Sufianov, Camillo Ruiz, Yuri Iakimov, Huerta Jose Mogorron, Manuel De Jesus Encarnación Ramírez, Guillermo Daniel Prat, Bárbara Lorea, Matías Baldoncini, Evgeniy Goncharov, Issael Ramírez, José R. Cerda, Renat Nurmukhametov, Nicola Montemurro,

The advance in imaging techniques is useful for 3D models and printing leading to a real revolution in many surgical specialties, in particular, neurosurgery.We report on a clinical study on the use of 3D printed models to perform cranioplasty in patients with craniosynostosis. The participants were recruited from various medical institutions and were divided into two groups: Group A (n = 5) received traditional surgical education (including cadaveric specimens) but without using 3D printed models, ...

Tópico(s): Facial Trauma and Fracture Management

2023 - Multidisciplinary Digital Publishing Institute | Brain Sciences

Artigo Revisado por pares

Manuel Martinez-Albarran, Jose de Jesus Perez-Molina, Sergio Gallegos‐Castorena, Fernando Sánchez‐Zubieta, Susana del Toro‐Arreola, Rogelio Troyo‐Sanromán, Óscar González-Ramella,

Procalcitonin and C-reactive-protein are inflammatory markers for sepsis. The authors evaluated their sensitivity and specificity in pediatric patients with cancer and febrile neutropenia.Serum procalcitonin and C-reactive-protein were evaluated. Patients (n = 54) were divided into 2 groups, with severe infection (n = 18) or without documented infection (n = 36).Procalcitonin and C-reactive protein were significantly higher in the high-risk group. Procalcitonin displayed 72.2% sensitivity and 80.5% specificity. ...

Tópico(s): Bacterial Identification and Susceptibility Testing

2009 - Taylor & Francis | Pediatric Hematology and Oncology

Artigo Revisado por pares

Paulo M. De Oliveira‐De Jesus, Manuel Alvarez, José M. Yusta,

This paper presents a new load flow formulation to solve active and passive electric distribution networks. The fundamental idea discussed here is how to obtain the power flow solution by using the elements of a unique quasi-symmetric matrix called TRX in the iterative process. The method is formulated for single-phase balanced and three-phase unbalanced radially operated networks. It works with real variables as opposed to complex variables used in previous backward/forward sweep algorithms discussed ...

Tópico(s): Islanding Detection in Power Systems

2012 - Elsevier BV | Electric Power Systems Research

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Alfeu Accorsi-Neto, Mauro Abi Haidar, Ricardo Santos Simões, Manuel de Jesus Simões, José Maria Soares, Edmund Chada Baracat,

The aim of this study was to evaluate the effects of isoflavones on the skin of postmenopausal women.A prospective study was performed with 30 postmenopausal women before and immediately after the end of treatment with 100 mg/day of an isoflavones-rich, concentrated soy extract for six months. A skin punch was performed in the gluteal region for sample collection before and immediately after the treatment program. Morphometric determination of epidermal thickness, the papillary index (wrinkling), ...

Tópico(s): Phytochemicals and Antioxidant Activities

2009 - Elsevier BV | Clinics

Artigo Brasil Produção Nacional Revisado por pares

José Carlos Chaves, Djalma José Fagundes, Manuel de Jesus Simões, Paulo Roberto Bertoletto, Celina T. F. Oshima, Murched Omar Taha, Ricardo Santos Simões, Anna Luiza Negrini Fagundes,

Abstract Purpose: The present paper aimed to investigate the role of hyperbaric oxygen treatment (HBO) and the apoptosis in rat liver ischemia‐reperfusion injury (IRI). Methods: Thirty‐seven male Wistar rats were subjected to 30 minutes of hepatic ischemia and 30 minutes of reperfusion and randomly distributed into six groups: G‐I/R ( n = 8), control without HBO; G‐HBO/I ( n = 8), HBO only during the ischemia period; G‐HBO/R ( n = 8), HBO only during the reperfusion period; G‐HBO‐I/R ( n = 8), HBO during both the ...

Tópico(s): Mesenchymal stem cell research

2009 - Wiley | Microsurgery

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Regina Célia Teixeira Gomes, Carina Verna, Helena B. Nader, Ricardo Santos Simões, Juliana L. Dreyfuss, João Roberto Maciel Martins, Edmund Chada Baracat, Manuel de Jesus Simões, José Maria Soares,

Objective To quantify and study the immunoexpression of hyaluronic acid (HA) in the uterine horns of the mouse throughout the estrous cycle phases. Design Experimental study using an ELISA-like fluorometric assay to quantify HA and an avidin-biotin immunoperoxidase method using biotinylated hyaluronan-binding protein for histochemical studies. Setting University-based laboratory. Animal(s) Forty regularly cycling adult female mice were divided into four groups according to the diagnosed phase of the cycle: ...

Tópico(s): Reproductive System and Pregnancy

2008 - Elsevier BV | Fertility and Sterility

Artigo Brasil Produção Nacional Revisado por pares

Marcio Moreira, Djalma José Fagundes, Manuel de Jesus Simões, Murched Omar Taha, Luciene Meri Neves Perez, Roberto Barbosa Bazotte,

ABSTRACT Capsular contracture is a potential adverse effect of breast implants. An inflammatory reaction is most likely the origin of fibrosis around the implant. It is possible that some substances may act to prevent this inflammatory reaction. Thus, our goal was to evaluate the effectiveness of local depot prednisolone phosphate‐liposomes (PPL) on fibrous capsule formation around textured silicone breast implants. Shell prostheses (2 mL) were implanted in the right (plus PPL group) and left (plus ...

Tópico(s): Tissue Engineering and Regenerative Medicine

2010 - Wiley | Wound Repair and Regeneration

Artigo Brasil Produção Nacional Revisado por pares

João Vidigal, Djalma José Fagundes, Manuel de Jesus Simões, Celina T. F. Oshima, Alexandre Nakao Odashiro, Ricardo Santos Simões, Anna Tereza Negrini Fagundes, Murched Omar Taha, Edna Frasson de Souza Montero,

Abstract The effect of hyperbaric oxygen (HBO) on ischemia‐reperfusion injury of skeletal muscle, applied during different periods, was studied in 56 male rats. Animals were subjected to 6‐h ischemia by a tourniquet over the major femoral trocanter and 4 (A) or 24 (B) h of reperfusion. HBO was carried out during 1 h in an acrylic chamber at a pressure of 2.0 ATA (100% oxygen): in the last 60 min of ischemia (II), after ischemia, during 1‐h reperfusion time (III), and during the last hour of ischemia plus ...

Tópico(s): Transplantation: Methods and Outcomes

2007 - Wiley | Microsurgery

Artigo Brasil Produção Nacional Revisado por pares

Maria Aparecida Galhardo, C. Quireze, Pedro Gabriel Riboli Navarro, Ricardo José Morello, Manuel de Jesus Simões, Edna Frasson de Souza Montero,

Abstract This study aimed the effect of n ‐acetylcysteine or ischemic preconditioning in hepatic and pulmonary damage after liver ischemia‐reperfusion injury. Twenty‐four male Wistar‐EPM rats were assigned into four groups: (IR) Hepatic ischemia‐reperfusion; (IPC) IPC achieved before hepatic ischemia; (NAC) Animals received NAC pretreatment; and Sham operated group. After 24 h of hepatic reperfusion, blood, liver, and pulmonary samples were evaluated. Nonparametric tests were used ( P ≤ 0.05). Aspartate ...

Tópico(s): Anesthesia and Neurotoxicity Research

2007 - Wiley | Microsurgery

Artigo Brasil Produção Nacional Revisado por pares

Adriana Aparecida Ferraz Carbonel, Michele Longoni Calió, Miriam Aparecida dos Santos, Clélia Rejane Antônio Bertoncini, G. da Silva Sasso, Ricardo Santos Simões, Manuel de Jesus Simões, José Maria Soares,

We evaluated whether genistein or estrogen treatment has the same effect when administered immediately or late to rats induced with menopause using ovariectomy.Sixty adult female rats were divided into six treatment groups: GI = vehicle immediately after ovariectomy; GII = vehicle 30 days after ovariectomy; GIII = genistein immediately after ovariectomy; GIV = genistein 30 days after ovariectomy; GV = estrogen immediately after ovariectomy; and GVI = estrogen 30 days after ovariectomy. All animals were treated ...

Tópico(s): Estrogen and related hormone effects

2014 - Taylor & Francis | Climacteric

Artigo Brasil Produção Nacional Revisado por pares

Murched Omar Taha, H.S Souza, César Alexandre Fabrega Carvalho, Djalma José Fagundes, Manuel de Jesus Simões, Neil Ferreira Novo, Afonso Caricati‐Neto,

Fibroblast growth factor receptor 1 (Fgfr1) gene knockout impairs cardiomyocyte differentiation in murine embryonic stem cells (mESC). Here, various chemical compounds able to enhance cardiomyocyte differentiation in mESC [including dimethylsulfoxide, ascorbic acid (vitC), free radicals and reactive oxygen species] were tested for their ability to rescue the cardiomyogenic potential of Fgfr1−/− mESC. Among them, only the reduced form of vitC, l-ascorbic acid, was able to recover beating cell differentiation ...

Tópico(s): Mitochondrial Function and Pathology

2004 - Elsevier BV | Transplantation Proceedings

Artigo Acesso aberto Revisado por pares

Pedro B. Água, Armindo Frias, Manuel de Jesus Carrasqueira, José Manuel Modas Daniel,

The 21st century endeavour bring new challenges for the maritime industry. The challenges facing the professionals within the industry are multifaceted and complex due to globalization, cross-cultural interrelationships, and technological change that are permeating the maritime industry. The aim of this article is to contribute to better understanding the problem of developing the future maritime industry professional, filling the existing gap between education and training programmes, while integrating ...

Tópico(s): Competency Development and Evaluation

2020 - University of Rijeka, Faculty of maritime studies | Pomorstvo

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Danilo José Fiorindo Faria, Manuel de Jesus Simões, José Luiz Martins,

PURPOSE: To investigate the effect of folic acid (FA) in an experimental model of anorectal malformations (ARMs) ethylenethiourea (ETU) induced. METHODS: Eight female Wistar rats were divided randomly in two groups. Group A - ETU; Group B - FA+ETU; Dams from group B received daily, since two weeks before pregnancy to the end of pregnancy, FA (50mg/kg) by gavage. Dams from groups A and B, received 1% ETU (125mk/kg) by gavage on gestational day (GD) 11. Their fetuses were harvested by cesarean section on GD21 ...

Tópico(s): Gastrointestinal disorders and treatments

2015 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira

Artigo Brasil Produção Nacional Revisado por pares

Paulo Roberto Bertoletto, Djalma José Fagundes, Manuel de Jesus Simões, Celina T. F. Oshima, Edna Frasson de Souza Montero, Ricardo Santos Simões, Anna Tereza Negrini Fagundes,

Abstract To examine the apoptosis expression in the intestinal mucosa in accordance of different periods of hyperbaric oxygen (HBO) treatment, rats were submitted to 60 min of mesenteric artery and vein ischemia and 60 min of reperfusion occlusion. A group (G‐IR) was the control and HBO was applied in the ischemia (GHBO‐I), reperfusion (GHBO‐R), and ischemia and reperfusion time (GHBO‐IR). After 60 min of reperfusion, samples of small bowel were prepared for immunohistochemical expression of caspase‐ ...

Tópico(s): Cardiac Ischemia and Reperfusion

2007 - Wiley | Microsurgery

Artigo Brasil Produção Nacional Revisado por pares

Andrea B. Moraes, Mauro Abi Haidar, José Maria Soares, Manuel de Jesus Simões, Edmund Chada Baracat, Marisa Teresinha Patriarca,

The aim of this study was to evaluate the effects of estrogen and isoflavones on postmenopausal skin morphological parameters.A randomized, double-blind, estrogen-controlled trial was performed on postmenopausal women treated in the Gynecology Department of the Federal University of São Paulo. This study was designed to analyze the effects of topical administration of estradiol and isoflavones on facial skin for 24 weeks. The participants were divided into two groups: G1-17-betaestradiol 0.01% (n= ...

Tópico(s): Skin Protection and Aging

2009 - Elsevier BV | European Journal of Obstetrics & Gynecology and Reproductive Biology

Artigo Brasil Produção Nacional Revisado por pares

F.A.G. Guimarães, Murched Omar Taha, Manuel de Jesus Simões, Djalma José Fagundes,

The aim of this work was to study the effects of hyperbaric oxygenation as a preservation technique for small bowel transplantation.Twenty 2-month-old male Wistar rats weighting 250 g were divided into two groups: group A (n = 10) in which the small bowel was preserved for 12 hours, and group B (n = 10) in which the small bowel was preserved for 24 hours. After vascular and intraluminal perfusion, 3-cm segments were maintained in Ringer's solution at temperatures between 2°C to 4°C and in normobaric O2 ...

Tópico(s): Transplantation: Methods and Outcomes

2002 - Elsevier BV | Transplantation Proceedings

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Angela Pötter de Castro, Miguel Angelo Martins de Castro, Susi Lauz, Emílio Facin, Manuel de Jesus Simões, Djalma José Fagundes,

To study the lesions in the lung of rabbits caused by ischemia/reperfusion hepatic (I/R) after the use of N-acetyl-cysteine (NAC).Twenty-four rabbits distributed in two groups: control group GI (n = 12) 5% glucose solution and experiment group GII (n = 12) NAC. The animals were pre-anesthetized with 1% acepromazine maleate and anesthetized with ketamine 10% and 2% xylazine intramuscularly. The GI and GII were given glucose solution intravenously or NAC 15 min before occlusion of the hepatic pedicle (30 min). ...

Tópico(s): Boron Compounds in Chemistry

2011 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira

Artigo Brasil Produção Nacional Revisado por pares

Cristiane Paula Teixeira, Ricardo Santos Simões, Maria Augusta B. dos Santos, Michele Longoni Calió, José Miguel Soares, Manuel de Jesus Simões, Clélia Rejane Antônio Bertoncini, Elisa Mieko Suemitsu Higa, Adriana Aparecida Ferraz Carbonel,

Objective To evaluate the effects of soy isoflavone extract in the pro-oxidant/antioxidant balance in the uterus of ovariectomized rats.Methods Twenty 3-month-old adult female Wistar rats were divided into four equal groups: GI: sham-operated (estrous phase); GII: control ovariectomized rats; GIII: ovariectomized rats treated with genistein (50 μg/kg/day) by gavage; GIV: ovariectomized rats subcutaneously treated with estrogen (10 μg/kg/day). After 30 consecutive days of treatment, the rats were euthanized ...

Tópico(s): Estrogen and related hormone effects

2013 - Taylor & Francis | Climacteric

Artigo Brasil Produção Nacional Revisado por pares

José Maria Soares, Manuel de Jesus Simões, Celina T. F. Oshima, Oswaldo Alves Mora, Gepatrik Rodrigues Lima, Edmund Chada Baracat,

The aim of this study was to evaluate the rat ovarian morphological and function changes after pinealectomy (px). Two months after px ,young female Wistar rats were sacrificed and the right ovaries were analysed morphologically and the left ovaries were used for steroid receptor binding experiments. Blood was collected and steroid hormone and melatonin levels were measured using radioimmunoassay kits. Results revealed that in the px group the rat ovaries had an increase in the number of atretic follicles ...

Tópico(s): Ovarian function and disorders

2003 - Informa | Gynecological Endocrinology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Paulo Roberto Bertoletto, José Carlos Chaves, Anna Tereza Negrini Fagundes, Ricardo Santos Simões, Celina Tizuko Fujiyama Oshima, Manuel de Jesus Simões, Djalma José Fagundes,

PURPOSE: To determine whether hyperbaric oxygen (HBO) could effectively protect the small intestine mucosa against an ischemic insult, according to different periods of application. METHODS: The gut of 32 male rats was subjected to 60-min ischemia (clamping the mesenteric artery and vein); After they were further reperfused upon clamp opening during 60 min. Animal groups were as follows. GII = placed on HBO during the ischemia period; GIII = placed on HBO during reperfusion; GIV = treated with HBO throughout ...

Tópico(s): Hydrogen's biological and therapeutic effects

2008 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira