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Artigo Revisado por pares

Mercedes Fernández-Cabana, Alejandro García-Caballero, Maria Perez, Manuel García‐García, Raimundo Mateos,

Linguistic inquiry and word count (LIWC), a computerized method for text analysis, is often used to examine suicide writings in order to characterize the quantitative linguistic features of suicidal texts.To analyze texts compiled in Marilyn Monroe's Fragments using LIWC, in order to explore the use of different linguistic categories in her narrative over the years.Selected texts were grouped into four periods of similar word count and processed with LIWC. Spearman's rank correlation was used to ...

Tópico(s): Grief, Bereavement, and Mental Health

2012 - Hogrefe Verlag | Crisis

Artigo Acesso aberto Revisado por pares

German Hernández Escarcega, Esteban Sánchez, Sandra Pérez Álvarez, Mayra Cristina Soto‐Caballero, Juan Manuel Soto Parra, María Antonia Flores‐Córdova, Nora A. SALAS-SALAZAR, Dámaris Leopoldina Ojeda‐Barrios,

Pomegranate is known for high concentration of antioxidant phenolics contained in its seeds, and peel, and is considered "healthy" due to its nutritional content and biological actions. The aim of this study was to determine the nutritional quality, volatile and phenolic antioxidants in the juice, peel and seeds of pomegranate from two different regions of Mexico. The pomegranate variety Wonderful of the 2016 cycle, obtained from the Coyame and Cuauhtémoc regions of the state of Chihuahua, Mexico, ...

Tópico(s): Plant Physiology and Cultivation Studies

2020 - Marcel Dekker | International Journal of Food Properties

Artigo Revisado por pares

Douglas W. Allen,

... org/10.1016/j.retrec.2010.07.008Gonzalo Caballero Miguez, María Dolores Garza Gil, Manuel M. Varela Lafuente The institutional foundations of economic ...

Tópico(s): Economic theories and models

1991 - University of Chicago Press | The Journal of Law and Economics

Artigo Acesso aberto Revisado por pares

Mi Kwon, Gloria Iacoboni, Juan Luís Reguera, Lucía López‐Corral, Rafael Hernani, Valentín Ortiz‐Maldonado, Manuel Guerreiro, A Caballero, María Luisa Guerra-Domínguez, José María Sánchez Pina, Alberto Mussetti, Juan‐Manuel Sancho, Mariana Bastos‐Oreiro, Eva Catalá, Javier Delgado, Hugo Luzardo, Jaime Sanz, María Calbacho, Rebeca Bailén, Cecilia Carpio, Jose Maria Ribera, Anna Sureda, Javier Briones, Juan Carlos Hernández‐Boluda, Nuria Martínez Cebrián, José L. Díez‐Martín, Alejandro Martı́n, Pere Barba,

Axicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) are CD19-targeted chimeric antigen receptor (CAR) T cells approved for relapsed/refractory (R/R) large B-cell lymphoma (LBCL). We performed a retrospective study to evaluate safety and efficacy of axi-cel and tisa-cel outside the setting of a clinical trial. Data from consecutive patients with R/R LBCL who underwent apheresis for axi-cel or tisa-cel were retrospectively collected from 12 Spanish centers. A total of 307 patients underwent ...

Tópico(s): Virus-based gene therapy research

2022 - Ferrata Storti Foundation | Haematologica

Artigo Revisado por pares

David de Gonzalo‐Calvo, Kim Neitzert, María Fernández Fernández, Ignacio Vega‐Naredo, Beatriz Caballero, Marina García‐Macia, Francisco Manuel Suárez, María Josefa Rodríguez‐Colunga, Juan J. Pérez-Solano, Ana Coto‐Montes,

Oxidative stress has been reported to increase during aging and conditions of hypoxia. Although low oxygen saturation has a key role in the development of several age-related diseases, the underlying mechanisms are still unknown. We analyzed the relationship between aging and hypoxia by examining oxidative stress and inflammation-related cytokines. We collected blood samples from three volunteer experimental groups, consisting of one group of normoxic middle-aged people and two groups of individuals ...

Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms

2010 - Elsevier BV | Free Radical Biology and Medicine

Artigo Revisado por pares

Arturo San Feliciano, José M. Miguel del Corral, Esther Caballero, Ana Maria Ardila Alvarez, Manuel Medarde,

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCantabric Acids. Triquinane Sesquiterpenoids from Artemisia cantabricaArturo San Feliciano, José M. Miguel Del Corral, Esther Caballero, Ana Alvarez, and Manuel MedardeCite this: J. Nat. Prod. 1986, 49, 5, 845–853Publication Date (Print):September 1, 1986Publication History Published online1 July 2004Published inissue 1 September 1986https://pubs.acs.org/doi/10.1021/np50047a014https://doi.org/10.1021/np50047a014research-articleACS PublicationsRequest reuse ...

Tópico(s): Plant Toxicity and Pharmacological Properties

1986 - American Chemical Society | Journal of Natural Products

Artigo Revisado por pares

Juana Ciudad, Jesús F. San Miguel, M C López-Berges, María‐Belén Vidriales, Berta Valverde, Mauricio Ocqueteau, G. Ares Mateos, Marı́a Dolores Caballero, Jesús María Hernández‐Rivas, Manuel Moro, MV Mateos, Alberto Órfão,

PURPOSE The identification of immunophenotypic aberrancies through multiparametric flow cytometry makes the differentiation between normal and leukemic cells relatively simple and quick, and is therefore an attractive method for the investigation of minimal residual disease (MRD). In this report, we have analyzed the impact on relapse and relapse-free survival (RFS) of detecting immunophenotypical aberrant cells in acute lymphoblastic leukemia (ALL) patients in cytomorphologic complete remission (CR). ...

Tópico(s): Retinoids in leukemia and cellular processes

1998 - Lippincott Williams & Wilkins | Journal of Clinical Oncology

Artigo Revisado por pares

Marc Sorigué, Santiago Mercadal, Sara Alonso, Rubén Fernández-Álvarez, Olga García, Miriam Moreno, Helena Pomares, Miguel Alcoceba, Esther González‐García, Cristina Motlló, Eva González‐Barca, Alejandro Martı́n, Anna Sureda, Dolores Caballero, Josep‐María Ribera, Juan‐Manuel Sancho,

Follicular lymphoma is characterized by a good response to immunochemotherapy (ICT). However, a small percentage of patients responds poorly to treatment and seems to have a worse outcome. This study attempted to identify the predictive factors and outcome of refractoriness to first-line ICT. All patients diagnosed with stage II to IV follicular lymphoma between 2002 and 2014 and treated with first-line ICT in 4 Spanish institutions were analyzed. Those with no response or progression or relapse ...

Tópico(s): Ovarian cancer diagnosis and treatment

2017 - Wiley | Hematological Oncology

Artigo Acesso aberto Revisado por pares

David de Gonzalo‐Calvo, Kim Neitzert, María Fernández Fernández, Ignacio Vega‐Naredo, Beatriz Caballero, Marina García‐Macia, Francisco Manuel Suárez, María Josefa Rodríguez‐Colunga, Juan J. Pérez-Solano, Ana Coto‐Montes,

The present study investigated the changes in several erythrocyte oxidative stress biomarkers in hypoxic elderly individuals to analyze the deleterious effects of low oxyhemoglobin saturation in an elderly population. We collected blood samples from one normoxic middle-aged group and two groups composed of individuals older than 75 years of age: one normoxic group and one hypoxic group. Aging appeared to provoke a defective erythrocyte antioxidant defense associated with increased oxidative damage ...

Tópico(s): Adipose Tissue and Metabolism

2010 - Oxford University Press | The Journals of Gerontology Series A

Artigo Acesso aberto Revisado por pares

Gonzalo Caballero Míguez, María Dolores Garza Gil, Manuel María Varela Lafuente,

This paper analyses the institutional foundations of the mussel production sector in Galicia, which is one of the leading producers in the world. After demonstrating the importance of the sector and presenting the theoretical framework and an historical introduction, the paper formulates an agenda of institutional analysis topics from a positive perspective. This agenda includes the problem of the common pool, the role of the State, the legal norms, the property rights system, the organisation of ...

Tópico(s): Cooperative Studies and Economics

2008 - Elsevier BV | Marine Policy

Artigo Revisado por pares

Gonzalo Caballero Míguez, María Dolores Garza Gil, Manuel María Varela Lafuente,

Institutional analysis is among the most significant research programs in the economics of fisheries management, and it increases our understanding of the relationships between the institutional framework and the fishing sector. Galicia is one of the most important fishing regions in the European Union, and this paper analyses the Galician fishing sector from a new institutional economics approach. The paper studies several topics that characterise the relationship between institutional rules and ...

Tópico(s): Local Government Finance and Decentralization

2008 - Elsevier BV | Ocean & Coastal Management

Artigo Acesso aberto Revisado por pares

Ignacio Constanso-Conde, Manuel Hermida‐Prieto, Eduardo Barge‐Caballero, Lucía Núñez, Jorge Pombo-Otero, Natalia Suárez-Fuentetaja, María J. Paniagua‐Martín, Gonzalo Barge‐Caballero, David Couto‐Mallón, Ricardo Pan-Lizcano, José Manuel Vázquez‐Rodríguez, María G. Crespo‐Leiro,

Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is needed. Tentative candidates could be circulating microRNAs. This study aimed to discover and validate microRNAs in serum for ACR detection after HTx.This prospective, observational, single-center study included 121 HTx patients. ACR was graded according to International Society of Heart and Lung Transplantation ...

Tópico(s): RNA Interference and Gene Delivery

2020 - Elsevier BV | The Journal of Heart and Lung Transplantation

Artigo

A. Mart�nez, Jesús F. San Miguel, María‐Belén Vidriales, Juana Ciudad, M. D. Caballero, M. C. L�pez-Berges, Manuel Moro, María José Calmuntia, Fernando Ortega, Alberto Órfão,

During conventional follow-up of patients with acute myeloid leukemia (AML), the emergence of cytopenias is considered to be a sign of impending relapse, and it represents an example of how leukemic hematopoiesis affects normal hemopoietic differentiation. In the present study, we have explored the possible value of the analysis of the distribution of CD34+ myeloid and CD34+ lymphoid progenitor cells in follow-up complete remission bone marrow samples from de novo AML patients as a prognostic parameter ...

Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment

1999 - Wiley | Cytometry

Artigo Acesso aberto Revisado por pares

Javier Monleón, María Luisa Cañete, Virginia Caballero, Manuel del Campo, Alejandro Doménech, Miguel Á. Losada, Joaquím Calaf,

Characterization of the clinical features of symptomatic uterine myomas in Spanish women visiting the gynaecologist, including impact on quality of life and possible risk factors, description of main therapeutic approaches, and evaluation of symptom and quality of life progression 6 months after inclusion in the study.This was an observational, epidemiological, non-interventional, multicentre study performed between June 2015 and March 2016. Data were collected at baseline and follow-up visits 6 ...

Tópico(s): Gynecological conditions and treatments

2018 - Elsevier BV | European Journal of Obstetrics & Gynecology and Reproductive Biology

Artigo Revisado por pares

Mari Cruz Almaraz, Stella González‐Romero, Manuel Bravo, Félix Francisco Caballero, María José Berlanga Palomo, Rosario Vallejo, Isabel Esteva, Fernando Calleja, Federico Soriguer,

Aims We studied the changes in the incidence of lower limb amputation (LLA) in Andalusia from 1998 to 2006 in the population with and without diabetes. Methods We undertook a retrospective study of all LLA performed in Andalusia in people aged 30 years old, with or without diabetes, between 1 January 1998 and 31 December 2006. We obtained the crude and standardized incidence rates by year, and sex for three periods: 1998–2000, 2001–2003 and 2004–2006 and calculated the RR of requiring LLA in patients ...

Tópico(s): Wound Healing and Treatments

2011 - Elsevier BV | Diabetes Research and Clinical Practice

Artigo Revisado por pares

Esther de la Hera, María Talegón, Pedro A. Caballero, Manuel Gómez,

Abstract BACKGROUND: Maize, one of the suitable grains for coeliac consumption, is, together with rice, the most cultivated cereal in the world. However, the inclusion of maize flour in gluten‐free bread is a minority and studies are scarce. This paper analyses the influence of different maize flour types and their particle sizes on the quality of two types of bread without gluten (80% and 110% water in the formulation) obtained from them. We also analysed the microstructure of the dough and its ...

Tópico(s): Microbial Metabolites in Food Biotechnology

2012 - Wiley | Journal of the Science of Food and Agriculture

Artigo Revisado por pares

Manuel Almendro‐Delia, María José Valle-Caballero, Juan C. Garcı́a-Rubira, Blanca Muñoz-Calero, Ángel García-Alcántara, Antonio Reina-Toral, José Benítez-Parejo, Rafael Hidalgo-Urbano,

The prognostic ability of atrial fibrillation (AF) in acute coronary syndromes (ACS) is unclear. Studies regarding patient outcomes with respect to the timing of AF are scarce and conflicting. The present study aimed to determine the frequency, predictors and impact on clinical outcome of AF in patients with ACS. We analysed 39,237 consecutive patients with ACS included in the ARIAM registry between January /2001 and December 2011. Patients with AF were compared with patients in sinus rhythm. We differentiate ...

Tópico(s): Cardiac Imaging and Diagnostics

2013 - Oxford University Press | European Heart Journal Acute Cardiovascular Care

Artigo Acesso aberto Revisado por pares

Isabel García‐Cao, Angeles Durán, Manuel Collado, Maria J Carrascosa, Juan Martín‐Caballero, Juana M. Flores, Marı́a T. Diaz-Meco, Jorge Moscat, Manuel Serrano,

The proapoptotic protein encoded by Par4 (prostate apoptosis response 4) has been implicated in tumour suppression, particularly in the prostate. We report here that Par4-null mice are prone to develop tumours, both spontaneously and on carcinogenic treatment. The endometrium and prostate of Par4-null mice were particularly sensitive to the development of proliferative lesions. Most (80%) Par4-null females presented endometrial hyperplasia by 9 months of age, and a significant proportion (36%) developed ...

Tópico(s): Mechanisms of cancer metastasis

2005 - Springer Nature | EMBO Reports

Artigo Acesso aberto Revisado por pares

Alicia Aurora Rodríguez, Óscar Martínez, Imanol Amayra, Juan Francisco López Paz, Mohammad Al‐Rashaida, Esther Lázaro, Patricia Caballero, Manuel Pérez, Sarah Berrocoso, Maitane García, Paula María Luna, Paula Pérez-Núñez, Nicole Passi,

This study aims to evaluate the costs of informal care for children with neuromuscular disease and evaluate how physical and psychological health is associated with socio-demographic variables. A cross sectional design was used with a convenience sample of 110 carers that participated in this study. Participants were recruited from Spanish hospitals and rare diseases organizations. Economic costs and sociodemographic aspects were assessed using the economic costs questionnaire and the sociodemographic ...

Tópico(s): Family Support in Illness

2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health

Revisão Acesso aberto Revisado por pares

Federico Martinón‐Torres, Eileen Png, Chiea Chuen Khor, Sonia Dávila, Victoria Wright, Kar Seng Sim, Ana Vega, Laura Fachal, David Inwald, Simon Nadel, Enitan D. Carrol, Federico Martinón‐Torres, Sonia Marcos Alonso, Ángel Carracedo, Elvira Morteruel, J. López Bayón, Andrés Concha, Cristina Calvo Monge, Pilar Azcón González de Aguilar, Elisabeth Esteban, María del Carmen Martínez‐Padilla, José María Martinón‐Sánchez, Michael Levin, Martin L. Hibberd, Antonio Salas, Alberto Gómez‐Carballa, Miriam Cebey‐López, Natalia García Sánchez, Irene Rivero‐Calle, Antonio Justicia Grande, Jacobo Pardo‐Seco, Ruth Barral‐Arca, Sara Pischedda, María José Currás-Tuala, Carmen Rodrı́guez-Tenreiro, Lorenzo Redondo-Collazo, Fernanda Pardo Sánchez, Jesús de la Cruz Moreno, Ma. Leticia Millán Miralles, José Luis García García, Susana Rey García, Ana Hurtado Doce, Armando Bautista Barba, Manuel Ortiz Pallares, Alfredo Reparaz Romero, J.I. Muñoz Bonet, Manuel Silveira Cancela, Eider Oñate Bergara, A. Bustinza Arriortúa, María Luisa Navarro Gómez, Mario Sánchez Fernández, Xavier Allué Martínez, Álvaro Castellanos-Ortega, S Rosso, C. Pérez Caballero Macarrón, N. Molini Menchón, F. Giménez Sánchez, Manuel González-Ripoll Garzón, María del Mar Ballesteros García, José Manuel Sánchez Granados, Olga Serrano Ayestarán, Roman Payo, Sonia Cañadas, Maria Cruz León León, Susana Reyes, David Arjona Villanueba, J. Antonio Alonso Martín, Concepción Goñi Orayen, E. Bernaola Iturbe, María Teresa Alonso Salas, Isabel Quintela Fernández, Robert Booy, Lachlan Coin, Hariklia Eleftherohorinou, Saul N. Faust, Rachel Galassini, Parviz Habibi, Elene Haralambous, Simon Kroll, Paul R. Langford, Nazima Pathan, Andrew J. Pollard, Farhana Abdulla, Paul‐Michael Agapow, Evangelos Bellos, Shea Hamilton, Jethro Herberg, Clive Hoggart, Myrsini Kaforou, Meg Mashbat, Sobia Mustafa, Vanessa Sancho‐Shimizu,

Abstract Meningococcal disease (MD) remains an important infectious cause of life threatening infection in both industrialized and resource poor countries. Genetic factors influence both occurrence and severity of presentation, but the genes responsible are largely unknown. We performed a genome-wide association study (GWAS) examining 5,440,063 SNPs in 422 Spanish MD patients and 910 controls. We then performed a meta-analysis of the Spanish GWAS with GWAS data from the United Kingdom (combined cohorts: ...

Tópico(s): Genetics and Neurodevelopmental Disorders

2016 - Nature Portfolio | Scientific Reports

Artigo Revisado por pares

Cécile A. J. Girardin, William Farfán-Ríos, Karina García, Kenneth J. Feeley, Peter M. Jørgensen, Alejandro Araujo Murakami, Leslie Cayola Pérez, Renate Seidel, Narel Paniagua, A C., Carla Maldonado, Miles R. Silman, Norma Salinas, Carlos Reynel, David Neill, Martha Serrano, Carlos J. Caballero, María de los Ángeles La Torre‐Cuadros, Manuel J. Macía, Timothy J. Killeen, Yadvinder Malhi,

Background: The Amazon to Andes transition zone provides large expanses of relatively pristine forest wilderness across environmental gradients. Such elevational gradients are an excellent natural laboratory for establishing long-term interactions between forest ecosystems and environmental parameters, which is valuable for understanding ecosystem responses to environmental change. Aims: This study presents data on elevational trends of forest structure (biomass, basal area, height, stem density), ...

Tópico(s): Fire effects on ecosystems

2013 - Taylor & Francis | Plant Ecology & Diversity

Artigo Revisado por pares

G. Rodríguez-Caballero, F. Caravaca, María del Mar Alguacil, Manuel Fernández‐López, Antonio J. Fernández‐González, A. Roldán,

The objective of this study was to determine whether native and invasive plants harbor different bacterial communities in their rhizospheres and whether there are bacterial indicator species associated with the invasive rhizosphere. Additionally, physico-chemical, biochemical, and biological properties have been determined in the native and invasive rhizospheres in order to ascertain the relationships between these soil properties and the rhizosphere bacterial communities. We carried out a study ...

Tópico(s): Genomics and Phylogenetic Studies

2017 - Elsevier BV | Soil Biology and Biochemistry

Artigo Acesso aberto Revisado por pares

Najlae El Kertaoui, C.M Hernández-Cruz, Daniel Montero, María José Caballero, Reda Saleh, Juan Manuel Afonso, Marisol Izquierdo,

Despite the interest of meagre (Argyrosomus regius) as a fast-growing candidate for Mediterranean aquaculture diversification, there is a lack of information on nutrition along larval development. Importance of highly unsaturated fatty acids (HUFA) and the antioxidant vitamins E and vitamin C has not been investigated yet in this species. Six diets with two levels of HUFA (0.4% and 3% dw), two of vitamin E (1500 and 3000 mg kg−1) and two of vitamin C (1800 and 3600 mg kg−1) were fed to 15 dah meagre ...

Tópico(s): Aquaculture disease management and microbiota

2015 - Wiley | Aquaculture Research

Artigo Acesso aberto Revisado por pares

Vanessa Benítez-Dorta, María José Caballero, Mónica B. Betancor, Manuel Manchado, Lluís Tort, Silvia Torrecillas, M. J. Zamorano, Marisol Izquierdo, Daniel Montero,

The present study examined the short and mid-term effects of a rise in temperature from 18 °C to 24 °C on the expression of genes related to the stress response regulation in juveniles of Senegalese sole, Solea senegalensis. The animals were exposed to a temperature increase of 6 °C, after 1 month of acclimation at 18 °C. After this process, samples of different tissues were collected from a total of 96 fish at four sampling points: 1 h, 24 h, 3 days and 1 week. The transcript levels of a set of genes ...

Tópico(s): Aquaculture Nutrition and Growth

2017 - Elsevier BV | General and Comparative Endocrinology

Artigo Revisado por pares

Armando López‐Guillermo, Miguel Canales, Iván Dlouhy, Javier Briones, Dolores Caballero, Juan‐Manuel Sancho, Santiago Mercadal Vilchez, José M. Moraleda, María José Terol, Antonio Salar, Luis Palomera, Santiago Gardella, Isidro Jarque, Secundino Ferrer, Joan Bargay, Andrés López, Carlos Panizo, A. Muntañola, Carlos Montalbán, Eulogio Conde, Miguel‐Teodoro Hernández, A. Soler, Julián Marín, Jose García Marco, Guillermo Debén, José Francisco Tomás,

Abstract Patients with FL can have long time of survival, but disease progression typically occurs 3-5 years after initial treatment. Consolidation with Z after initial therapy has shown to improve progression-free survival (PFS) mainly in the pre-R era, whereas maintenance with R also has demonstrated a substantial benefit in terms of PFS in patients treated with immunochemotherapy. In this setting, the Spanish intergroup PETHEMA/GELTAMO/GELCAB started a randomized phase 2 trial in order to compare ...

Tópico(s): Chronic Lymphocytic Leukemia Research

2013 - Elsevier BV | Blood

Artigo Revisado por pares

Juan Diego Maya, Antonio Morello, Yolanda Repetto, Andrés Rodrı́guez, Pilar Puebla, Esther Caballero, Manuel Medarde, Luis J. Núñez‐Vergara, J.A. Squella, María Eugenia Ortiz, Jorge Fuentealba, Arturo San Feliciano,

Maya, J. D., Morello, A., Repetto, Y., Rodrı́guez, A., Puebla, P., Caballero, E., Medarde, M., Núñez-Vergara, L. J., Squella, J. A., Ortiz, M. E., Fuentealba, J., and San Feliciano, A. 2001. Trypanosoma cruzi: Inhibition of parasite growth and respiration by oxazolo(thiazolo)pyridine derivatives and its relationship to redox potential and lipophilicity. Experimental Parasitology99, 1–6. Chagas' disease constitutes a therapeutic challenge because presently available drugs have wide toxicity to the ...

Tópico(s): Synthesis and Biological Evaluation

2001 - Elsevier BV | Experimental Parasitology

Artigo Brasil Produção Nacional Revisado por pares

Beatriz de Luxán‐Delgado, Yaiza Potes, Adrian Rubio‐González, Beatriz Caballero, Juan J. Pérez-Solano, María Fernández Fernández, Manuel Bermúdez, Marcela Rodrigues Moreira Guimarães, Ignacio Vega‐Naredo, José Antonio Boga, Ana Coto‐Montes,

Abstract The sedentary lifestyle of modern society along with the high intake of energetic food has made obesity a current worldwide health problem. Despite great efforts to study the obesity and its related diseases, the mechanisms underlying the development of these diseases are not well understood. Therefore, identifying novel strategies to slow the progression of these diseases is urgently needed. Experimental observations indicate that melatonin has an important role in energy metabolism and ...

Tópico(s): Adipose Tissue and Metabolism

2016 - Wiley | Journal of Pineal Research