Ana Coelho, Anabela Paula, Marta Mota, Mafalda Laranjo, Ana Margarida Abrantes, Francisco Carrilho, Manuel Marques Ferreira, Mário Silva, Maria Filomena Botelho, Eunice Carrilho,
Objectives Since most of the studies evaluates diabetics on multiple daily injections therapy and continuous subcutaneous insulin infusion may help gain better metabolic control and prevent complications, the objective of this study was to evaluate the prevalence of dental caries, the unstimulated salivary flow rate and the total bacteria load, Streptococcus spp. levels and Lactobacillus spp. levels in saliva and supragingival dental biofilm of type 1 diabetics on insulin pump. Material and Methods ...
Tópico(s): Salivary Gland Disorders and Functions
2018 - UNIVERSIDADE DE SÃO PAULO | Journal of Applied Oral Science
João Caraça, Manuel Maria Carrilho,
Abstract The contemporary situation of knowledge points to a change in paradigm, if looked at from the perspective of a confluence of its essential elements, instead of as a dispersion of its often incongruous developments. The novelty comes from the emergence of the non-material order in the area of the material paradigm, for which it substitutes—only in this sense can one speak of substitution here—as an ordering paradigm of knowledge and of its transmission and circulation. Since the main models ...
Tópico(s): Italian Literature and Culture
1994 - Elsevier BV | Futures
Siri Paulo, Mafalda Laranjo, Ana Margarida Abrantes, João Casalta‐Lopes, Kathleen Santos, Ana Cristina Gonçalves, Anabela Paula, Carlos Miguel Marto, Ana Bela Sarmento‐Ribeiro, Eunice Carrilho, Arménio C. Serra, Maria Filomena Botelho, Manuel Marques Ferreira,
(1) Background: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is one of the most often seen side effects in patients treated with nitrogen-containing bisphosphonates (BPs), a post-surgical non-healing wound condition. Since calcium phosphate (CP) compounds are able to adsorb zoledronate (ZOL) when used as a drug delivery vehicle, we aimed to verify if these ceramics might have a potential protective effect for soft tissues surrounding surgical osseous wounds. (2) Methods: The chemical reaction ...
Tópico(s): Bone and Joint Diseases
2019 - Multidisciplinary Digital Publishing Institute | Materials
Inês Raquel Pereira, Catarina Carvalho, Siri Paulo, José Pedro Martinho, Ana Coelho, Anabela Paula, Carlos Miguel Marto, Eunice Carrilho, Maria Filomena Botelho, Ana Margarida Abrantes, Manuel Marques Ferreira,
The aim of this study was to evaluate and compare the sealing ability of two calcium silicate-based sealers (TotalFill BC RRM Fast Set Putty and White ProRoot MTA) when used as apical plugs in immature teeth through nuclear medicine. Single-rooted extracted teeth (n = 34) had their crowns and root tip sectioned to obtain 14 mm long root segments to simulate an in vitro apexification model. Were created two experimental groups, namely MTA (n = 12) and BC (n = 12), and two control groups, PG (positive group, ...
Tópico(s): Dental materials and restorations
2021 - Multidisciplinary Digital Publishing Institute | Materials
Miguel Melo, Gracinda Costa, Cristina Ribeiro, Francisco Carrilho, Maria João Martins, Adriana Gaspar da Rocha, Manuel Sobrinho‐Simões, Manuela Carvalheiro, Paula Soares,
Thyroglobulin (Tg) levels measured at the time of remnant ablation after thyroid hormone withdrawal (THW) were shown to have prognostic value in predicting disease-free status.Our objectives were to determine whether stimulated Tg levels, measured at the time of remnant ablation performed under recombinant human TSH (rhTSH) stimulation, has value in predicting absence of detectable disease 1 year after radioiodine therapy and to compare the results obtained with this approach with a cohort of patients ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2013 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
... problematique de La Rhetorique, l’ouvrage dirige par Manuel Maria Carrilho est compose de six textes et d’un ...
Tópico(s): Linguistics and Discourse Analysis
2012 - OpenEdition Journals | Lectures
Anabela Paula, Mafalda Laranjo, Carlos Miguel Marto, Siri Paulo, Ana Margarida Abrantes, João Casalta‐Lopes, Manuel Marques Ferreira, Maria Filomena Botelho, Eunice Carrilho,
Direct pulp capping therapies use biomaterials to protect exposed tissues, inducing repair through the production of a mineralized barrier. The purpose of this study was to compare the effectiveness of biomaterials and techniques by means of a systematic review and meta-analysis. The PubMed, Cochrane, and Embase databases were used to search the literature published from January 1, 1980 until August 31, 2017. Studies that met inclusion criteria were screened by 2 authors individually. The meta-analysis ...
Tópico(s): Surgical Sutures and Adhesives
2018 - Elsevier BV | Journal of Evidence Based Dental Practice
Anabela Paula, Mafalda Laranjo, Carlos Miguel Marto, Siri Paulo, Ana Margarida Abrantes, Bruno Fernandes, João Casalta‐Lopes, Manuel Marques Ferreira, Maria Filomena Botelho, Eunice Carrilho,
When exposure of the pulp to external environment occurs, reparative dentinogenesis can be induced by direct pulp capping to maintain pulp tissue vitality and function. These clinical situations require the use of materials that induce dentin repair and, subsequently, formation of a mineralized tissue.This work aims to assess the effect of tricalcium silicate cements and mineral trioxide aggregate cements, including repairing dentin formation and inflammatory reactions over time after pulp exposure ...
Tópico(s): Oral and Maxillofacial Pathology
2019 - UNIVERSIDADE DE SÃO PAULO | Journal of Applied Oral Science
Anabela Paula, Mafalda Laranjo, Carlos Miguel Marto, Ana Margarida Abrantes, João Casalta‐Lopes, Ana Cristina Gonçalves, Ana Bela Sarmento‐Ribeiro, Manuel Marques Ferreira, Maria Filomena Botelho, Eunice Carrilho,
(1) Background: When pulp exposure occurs, reparative dentinogenesis can be induced by direct pulp capping to maintain the vitality and function of the tissue. The aim of this work was to assess the cytotoxicity and bioactivity of three different direct pulp capping materials, calcium hydroxide (Life®), mineral trioxide aggregate (WhiteProRoot®MTA) and calcium silicate (Biodentine™), in an odontoblast-like mouse cell line (MDPC-23). (2) Methods: Metabolic activity was assessed by the 3-(4,5-dimethylthiazol- ...
Tópico(s): Bone and Dental Protein Studies
2019 - Multidisciplinary Digital Publishing Institute | Materials
Ana Coelho, Inês Amaro, Francisco Caramelo, Anabela Paula, Carlos Miguel Marto, Manuel Marques Ferreira, Maria Filomena Botelho, Eunice Carrilho,
Abstract Objective To analyze articles aimed at evaluating the association between diabetes, metabolic control, diabetes duration, and dental caries. Overview A systematic search in PubMed, Cochrane Library, Embase, and Web of Science was conducted to retrieve papers in English, Portuguese, and Spanish, up to April 2019. The research strategy was constructed considering the “PECO” strategy. Only quantitative observational studies were analyzed. The risk of bias was assessed using the Newcastle‐Ottawa ...
Tópico(s): Hyperglycemia and glycemic control in critically ill and hospitalized patients
2020 - Wiley | Journal of Esthetic and Restorative Dentistry
Joana B. Infante, Maria Inês Alvelos, Margarida Bastos, Francisco Carrilho, Manuel C. Lemos,
The androgen insensitivity syndrome is an X-linked recessive genetic disorder characterized by resistance to the actions of androgens in an individual with a male karyotype. We evaluated a 34-year-old female with primary amenorrhea and a 46,XY karyotype, with normal secondary sex characteristics, absence of uterus and ovaries, intra-abdominal testis, and elevated testosterone levels. Sequence analysis of the androgen receptor (AR) gene revealed a novel splice donor site mutation in intron 4 (c.2173 + ...
Tópico(s): Urological Disorders and Treatments
2015 - Elsevier BV | The Journal of Steroid Biochemistry and Molecular Biology
Tópico(s): French Urban and Social Studies
1989 - Editions Rationalistes | Raison présente
João Caraça, Manuel Maria Carrilho,
One of the points stressed in ‘A new paradigm in the organization of knowledge’, Futures, 26, 1994, pages 781–786, was the determinant role of sharing in the emergence and configuration of the paradigm of the immaterial. We resume the elements suggested then and develop their analysis in three stages: first, by characterizing the operational singularity of sharing; second, by considering its cognitive and disciplinary incidence; and finally, by pointing out its theoretical consequences, namely in ...
Tópico(s): Historical and Literary Studies
1996 - Elsevier BV | Futures
Notre epoque vit « pour le meilleur et pour le pire » l’heure de la rhetorique. Il suffit d’ouvrir la television, de regarder les messages publicitaires ou d’ecouter les hommes politiques. Le discours et l’image doivent interesser (docere), seduire (delectare) et convaincre (movere). La nouvelle rhetorique (retorica rediviva) n’est plus l’art du beau parler, mais la theorie de la communication efficace ; l’argumentation devient une composante essentielle de l’activite discursive en general, d...
Tópico(s): Linguistics and Discourse Analysis
2015 - Laval University | Communication
Ana Coelho, Mafalda Laranjo, Ana Cristina Gonçalves, Anabela Paula, Siri Paulo, Ana Margarida Abrantes, Francisco Caramelo, Manuel Marques Ferreira, Mário Jorge Silva, Eunice Carrilho, Maria Filomena Botelho,
Tópico(s): Photodynamic Therapy Research Studies
2019 - Springer Science+Business Media | Odontology
Edward Limbert, Susana Prazeres, Márcia São Pedro, Deolinda Madureira, Ana Miranda, Manuel Ribeiro, João Jácome de Castro, Francisco Carrilho, Maria João Oliveira, Henrique Reguengo, F. Borges, Lorie A. Kloda,
Iodine is the key element for thyroid hormone synthesis, and its deficiency, even moderate, is harmful in pregnancy, when needs are increased, because of its potential deleterious effects on fetal brain development. In Portugal, no recent data on iodine intake exists. The objective of this countrywide study was to analyze iodine status in pregnant Portuguese women in order to propose adequate measures to the health authorities.Using a fast colorimetric method, urine iodine concentration (UIC) was ...
Tópico(s): Neonatal Health and Biochemistry
2010 - Oxford University Press | European Journal of Endocrinology
Carlos Miguel Marto, Anabela Paula, Tiago Nunes, M. C. Pimenta, Ana Margarida Abrantes, Ana Salomé Pires, Mafalda Laranjo, Ana Coelho, Helena Donato, Maria Filomena Botelho, Manuel Marques Ferreira, Eunice Carrilho,
Abstract Objectives To compare the treatments used to treat dentin hypersensitivity (DH), based on its efficacy and effect duration. Methods Medline/PubMed, Cochrane Library, EMBASE and ClinicalTrials were searched for articles published between 1 January 2008 and 14 November 2018, in English, Portuguese or Spanish, reporting clinical trials, completed and with results. This systematic review protocol was registered in PROSPERO, number CRD42019121986. Results Seventy‐four randomised clinical trials ...
Tópico(s): Dental materials and restorations
2019 - Wiley | Journal of Oral Rehabilitation
Siri Paulo, Mafalda Laranjo, Anabela Paula, Ana Margarida Abrantes, João Filipe Brochado Martins, Carlos Miguel Marto, Ana Coelho, João Casalta‐Lopes, Lina Carvalho, Eunice Carrilho, Arménio C. Serra, Maria Filomena Botelho, Manuel Marques Ferreira,
Bisphosphonate-associated osteonecrosis of the jaw (BRONJ), a post-surgical non-healing wound condition, is one of the most common side effects in patients treated with nitrogen-containing bisphosphonates. Its physiopathology has been related with suppression of bone turnover, of soft tissue healing and infection. Biphasic calcium phosphates (BCP) are used as a drug delivery vehicle and as a bone substitute in surgical wounds. Due to their capacity to adsorb zoledronate, it was hypothesized these ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2020 - Multidisciplinary Digital Publishing Institute | Materials
Inês S. Ferreira, Mafalda Laranjo, Carlos Miguel Marto, João Casalta‐Lopes, Beatriz Serambeque, Ana Cristina Gonçalves, Ana Bela Sarmento‐Ribeiro, Eunice Carrilho, Maria Filomena Botelho, Anabela Paula, Manuel Marques Ferreira,
The sealers used for root canal treatment should be biocompatible for the peri-radicular tissues, to evaluate the cytotoxic effects of GuttaFlow
Tópico(s): Animal testing and alternatives
2020 - Multidisciplinary Digital Publishing Institute | Molecules
Manuel Marques Ferreira, Maria Filomena Botelho, Lina Carvalho, Bárbara Oliveiros, Eunice Carrilho,
Objective: The aim of this study was to assess the pulp survival that occur in transplants of autologous teeth, by comparing two surgical techniques: the conventional technique (autotransplantation for newly formed alveoli), and an alternative technique, (autotransplants for alveoli in the initial phase of healing).In each surgical techniques were applied, randomly, either saline solution or Emdogain ® .Study Design:The study group comprised 26 patents, in which 28 teeth were transplanted to recipient ...
Tópico(s): dental development and anomalies
2011 - Medicina Oral S.L. | Medicina oral, patología oral y cirugía bucal
Anabela Paula, Eunice Carrilho, Mafalda Laranjo, Ana Margarida Abrantes, João Casalta‐Lopes, Maria Filomena Botelho, Carlos Miguel Marto, Manuel Marques Ferreira,
(1) Background: Recently, tricalcium silicate cements, such as Biodentine™, have emerged. This biomaterial has a calcium hydroxide base and characteristics like mineral aggregate trioxide cements, but has tightening times that are substantially more suitable for their application and other clinical advantages. (2) Methods: A retrospective clinical study was conducted with 20 patients, which included a clinical evaluation of the presence or absence of pulp inflammation compatible symptoms, radiographic ...
Tópico(s): Dental Radiography and Imaging
2019 - Multidisciplinary Digital Publishing Institute | Materials
José Pedro Martinho, Sara Amorim França, Siri Paulo, Anabela Paula, Ana Coelho, Ana Margarida Abrantes, Francisco Caramelo, Eunice Carrilho, Carlos Miguel Marto, Maria Filomena Botelho, Henrique Girão, Manuel Marques Ferreira,
(1) Aim: This study aims to analyze the in vitro infiltration of a silicate root canal sealer into dentinal tubules after using different endodontic irrigating solutions. (2) Methods: Twenty-nine teeth with single roots were separated into three groups according to the final irrigation protocol: G1 n = 10) = 17% EDTA (ethylenediaminetetraacetic acid) + 3.0% sodium hypochlorite (NaOCl), G2 (n = 10) = 17% EDTA + 2.0% chlorhexidine and G3 (Control group, n = 9) = 17% EDTA + saline solution. Root canals were filled using ...
Tópico(s): Dental materials and restorations
2020 - Multidisciplinary Digital Publishing Institute | Materials
Manuel Marques Ferreira, Maria Filomena Botelho, Lina Carvalho, Oliveiros Barbara, Eunice Carrilho,
Abstract – Objective: To compare the periodontal regeneration, associated with autogenous tooth transplantation in dogs, using either one‐ or two‐stage surgical techniques. Methods: The study group consisted of three Beagles, older than 5 months, in which six incisors and six premolars were transplanted to mechanically prepared recipient sockets. One group was transplanted using a one‐stage method to recipient beds prepared immediately before transplantation. The second group of teeth were transplanted ...
Tópico(s): Cleft Lip and Palate Research
2010 - Wiley | Dental Traumatology
Pedro Carrilho‐Ferreira, Doroteia Silva, Maria de Jesus Silva, Rui André, Manuel Varela, António Nunes Diogo,
Adult-onset Still's disease is a rare disorder with potentially severe clinical features, including cardiac involvement. This systemic inflammatory disease of unknown origin should be considered in the differential diagnosis of pericarditis, with or without pericardial effusion. Cardiac tamponade is a very rare sequela that requires an invasive approach, such as percutaneous or surgical pericardial drainage, in addition to the usual conservative therapy. The authors describe a case of adult-onset ...
Tópico(s): Kawasaki Disease and Coronary Complications
2015 - Texas Heart Institute | Texas Heart Institute Journal
Anabela Paula, Mafalda Laranjo, Ana Coelho, Ana Margarida Abrantes, Ana Cristina Gonçalves, Ana Bela Sarmento‐Ribeiro, Manuel Marques Ferreira, Maria Filomena Botelho, Carlos Miguel Marto, Eunice Carrilho,
Biomaterials contact directly or indirectly with the human tissues, making it important to evaluate its cytotoxicity. This evaluation can be performed by several methods, but a high discrepancy exists between the approaches used, compromising the reproducibility and the comparison among the obtained results. In this paper, we propose a protocol to evaluate biomaterials cytotoxicity using soluble extracts, which we use for dental biomaterials. The extracts preparation is detailed, from pellets production ...
Tópico(s): 3D Printing in Biomedical Research
2021 - MyJOVE | Journal of Visualized Experiments

Carla Sakuma de Oliveira, Arnaldo Lopes Colombo, Elaine Cristina Francisco, Bernardo de Lima, Rinaldo Ferreira Gandra, Mariza Cristina Preifz de Carvalho, Cláudia Maria Dantas de Maia Carrilho, Renan Pontes Petinelli, Marsilene Pelison, César Helbel, Gerson Czelusniak, Hugo Manuel Paz Morales, Jamile Sardi Perozin, Rosângela Lameira Pinheiro, Regielly Caroline Raimundo Cognialli, Giovanni Luís Breda, Flávio Queiroz‐Telles,
Candida spp. has been reported as one of the common agents of nosocomial bloodstream infections and is associated with a high mortality. Therefore, this study evaluated the clinical findings, local epidemiology, and microbiological aspects of candidemia in eight tertiary medical centers in the state of Parana, South of Brazil. In this study, we reported 100 episodes of candidemia in patients admitted to eight different hospitals in five cities of the state of Parana, Brazil, using data collected ...
Tópico(s): Cystic Fibrosis Research Advances
2020 - Elsevier BV | The Brazilian Journal of Infectious Diseases
Manuel Marques Ferreira, Hugo Ferreira, Maria Filomena Botelho, Eunice Carrilho,
Autotransplantation combined with orthodontic treatment: a case involving the maxillary central incisors with root resorption after traumatic injuryTraumatic dental injury can result in avulsion of anterior teeth.In young patients, it is a challenge to the dental professional because after replantation, late complications such as ankylosis require tooth extraction.Although prosthetic and orthodontic treatment, and implant placement have been described as the options for intervention, autogenous ...
Tópico(s): dental development and anomalies
2015 - Korean Academy of Conservative Dentistry | Restorative Dentistry & Endodontics
Catherine M. Hastings, James Todd Hayes, M. Jimmie Killingsworth, Glen McClish, Brian Nerney, Marie Secor, Joyce Sutphen,
Rhétoriques de la modernité by Manuel Maria Carrilho. Paris: Presses Universitaires de France, 1992; pp. 170. The Place of Emotion in Argument by Douglas Walton. University Park, PA: The ...
Tópico(s): Media, Communication, and Education
1993 - Taylor & Francis | Rhetoric Society Quarterly
Manuel Marques Ferreira, José Pedro Martinho, Inês Duarte, Diogo Mendonça, Ana Catarina Craveiro, Maria Filomena Botelho, Eunice Carrilho, Carlos Miguel Marto, Ana Coelho, Anabela Paula, Siri Paulo, Nuno Chichorro, Ana Margarida Abrantes,
Obturation represents a critical step in endodontic treatment, which relies on a core material and a sealer. This study aims to evaluate the sealing ability and bond strength to the root canal walls of an epoxy resin-based sealer (AH-Plus®, Dentsply Sirona, Johnson City, TN, USA) and a bioceramic sealer (GuttaFlow Bioseal®, Coltène/Whaledent, GmbH + Co. KG, Langenau, Germany).Thirty-eight maxillary anterior teeth with single roots and identical round sections were separated into two experimental groups ...
Tópico(s): Dental materials and restorations
2022 - Multidisciplinary Digital Publishing Institute | Dentistry Journal
Manuel Marques Ferreira, Maria Filomena Botelho, Ana Margarida Abrantes, Bárbara Oliveiros, Eunice Carrilho,
The purpose of this study was to evaluate the pulpal changes associated with autogenous single-rooted immature tooth transplantation in dogs, using either one, or two-stage surgical techniques.Teeth from 3 beagle dogs, 5 months old, were extracted and transplanted to mechanically prepared recipient sockets. Group (A), where the teeth were transplanted using a one-stage method to recipient beds prepared immediately before transplantation. Group (B), where the teeth were transplanted using a two-stage ...
Tópico(s): Oral and Maxillofacial Pathology
2010 - Elsevier BV | Archives of Oral Biology