Lourdes Vicent, Manuel Martínez‐Sellés,
The heart, like most mammalian organs, is influenced by circadian patterns. The suprachiasmatic nucleus in the hypothalamus has a key role in this influence, via various neurohumoral factors, particularly the autonomic nervous system. In addition, a local cardiac peripheral clock might drive a circadian rhythm related to the expression of ion channels. Several myocardial functions are influenced by these circadian cycles including activity/rest, regeneration, nutrient storage, growth, and myocardial ...
Tópico(s): Heart Rate Variability and Autonomic Control
2021 - IMR Press | Frontiers in Bioscience-Landmark
Ana Ayesta, Gerard Urrútia, Eva Madrid, Robin W.M. Vernooij, Lourdes Vicent, Manuel Martínez‐Sellés,
Abstract Introduction and objectives Heart transplantation (HT) is the treatment for patients with end‐stage heart disease. Despite contradictory reports, survival seems to be worse when donor/recipient sex is mismatched. This systematic review and meta‐analysis aims to synthesize the evidence on the effect of donor/recipient sex mismatch after HT. Methods We searched PubMed and EMBASE until November 2017. Comparative cohort and registry studies were included. Published articles were systematically ...
Tópico(s): Heart Failure Treatment and Management
2019 - Wiley | Clinical Transplantation
Lourdes Vicent, Manuel Martínez‐Sellés,
The electrocardiogram (ECG) presents substantial changes associated with aging. In fact, the likelihood of having a "normal" ECG decreases with age. The most common findings are left ventricular hypertrophy pattern, leftward axis deviation and QRS widening. Interatrial block (IAB) is frequently present, mainly partial IAB. Atrial fibrillation prevalence raises from 6–7% in those aged 65–74 years to 13–17% in those > 75 years.
Tópico(s): Cardiac electrophysiology and arrhythmias
2017 - Elsevier BV | Journal of Electrocardiology
Marta González‐Vicent, Manuel Ramı́rez, Julián Sevilla, Lorea Abad, Miguel Ángel Díaz,
Extracorporeal photopheresis (ECP) has been used for treatment of steroid-refractory graft-versus-host disease (GVHD) with encouraging results. However, only a few pediatric centers have experienced with ECP, mainly by technical difficulties of leukapheresis in children. We retrospectively analyzed 27 patients treated during 5 years with ECP for steroid-refractory acute and chronic GVHD. We performed an "off-line" approach using a continuous flow cell separator (Cobe Spectra) and a Ultraviolet A irradiator ( ...
Tópico(s): T-cell and B-cell Immunology
2010 - Lippincott Williams & Wilkins | Journal of Pediatric Hematology/Oncology
Andrés G. Algarra, M. Feliz, M. Jesús Fernández‐Trujillo, Rosa Llusar, Vicent S. Safont, Cristian Vicent, Manuel G. Basallote,
Opening the cluster core: Substitution of the chloride ligand in the novel cationic cluster [W(3)CuS(4)H(3)Cl(dmpe)(3)](+) (see figure; dmpe=1,2-bis(dimethylphosphino)ethane) by acetonitrile is promoted by water addition. Kinetic and density functional theory studies lead to a mechanistic proposal in which acetonitrile or water attack causes the opening of the cluster core with dissociation of one of the Cu--S bonds to accommodate the entering ligand.Reaction of the incomplete cuboidal cationic cluster [ ...
Tópico(s): Organometallic Complex Synthesis and Catalysis
2009 - Wiley | Chemistry - A European Journal
Marta González‐Vicent, Manuel Ramı́rez, Antonio Pérez‐Martínez, Álvaro Lassaletta, Julián Sevilla, Miguel Ángel Díaz,
donation is considered.
Tópico(s): Photodynamic Therapy Research Studies
2008 - Ferrata Storti Foundation | Haematologica
Marta González‐Vicent, Manuel Ramı́rez, Julián Sevilla, Antonio Pérez‐Martínez, S. Fernández, Luís Madero, Miguel Ángel Díaz,
Tópico(s): Renal Transplantation Outcomes and Treatments
2004 - Springer Nature | Bone Marrow Transplantation
Luís Madero, Marta González‐Vicent, Manuel Ramı́rez, Víctor Quintero, Ana Benito, Miguel Ángel Díaz,
There is limited experience in the use of peripheral blood progenitor cells (PBPC) for allogeneic transplantation in children. In the present study we compared engraftment kinetics, incidence of acute and chronic graft-versus-host disease (GVHD) and the outcome and economic costs of allogeneic PBPCT vs BMT in children with ALL in a single institution. All children were transplanted in complete remission (CR) with a similar conditioning regimen and the same GVHD prophylaxis. Patients undergoing PBPCT ...
Tópico(s): Acute Myeloid Leukemia Research
2000 - Springer Nature | Bone Marrow Transplantation
Cristina Vicent, Manuel Martín‐Lomas, Soledad Penadés,
A simple strategy for the synthesis of highly symmetric macrocycles incorporating carbohydrates is presented. The application of this strategy to the synthesis of optically active tetra-gluco-24-crown-8 (1), bis-gluco-15-crown-5 (3), and bis-gluco-21-crown-8 (5) is described. Preliminary studies showed that macrocycles 1, 3 and 5 complex ammonium salts. These macrocyclic compounds have been used as catalysts in the asymmetric Michael addition of methyl α-phenylacetate to methyl acrylate.
Tópico(s): Molecular Sensors and Ion Detection
1989 - Elsevier BV | Tetrahedron
Moisés Guelrud, Sonia Mendoza, Simon Vicent, Manuel Romero–Gómez, Beatriz Villalta,
To determine the significance of manometric pressure, measurements of the sphincter of Oddi in a control group and in patients with cholelithiasis with common duct stones with and without recurrent pancreatitis were studied. Sphincter of Oddi pressure was recorded continuously and by station pull-through by a triple lumen catheter. The basal sphincter of Oddi pressure, the mean pressure gradient between common duct and duodenum, and the sphincter of Oddi ware amplitude were measured. There was no ...
Tópico(s): Pancreatitis Pathology and Treatment
1983 - Lippincott Williams & Wilkins | Journal of Clinical Gastroenterology
Juan Manuel Bermúdez‐García, José Manuel Vicent‐Luna, S. Yáñez‐Vilar, Said Hamad, Manuel Sánchez‐Andújar, Socorro Castro‐García, Sofı́a Calero, M. A. Señarís‐Rodríguez,
In this work we use molecular dynamics simulations to study the diffusion of N,N-dimethylformamide (DMF) and H2O as a function of temperature within the well-known metal-organic framework Co2(dobdc)·[G] (G = 2DMF·1H2O), also known as Co-MOF-74. The molecular dynamics simulations show that the diffusivity of guest molecules, which is almost negligible at low temperatures (T < 200 K), increases in the range of 200 < T (K) < 400 up to 3 and 4 orders of magnitude for DMF and H2O, respectively. This molecular diffusion ...
Tópico(s): Organic and Molecular Conductors Research
2016 - Royal Society of Chemistry | Physical Chemistry Chemical Physics
Jaime Feliú, P. Escudero, Ferrán Llosa, Matilde Bolaños, Jose-Manuel Vicent, A. Yubero, J. Sanz-Lacalle, Rafael López‐López, Luis López‐Gómez, E. Casado, M. J. Gómez-Reina, Manuel González-Barón,
To determine the tolerability of capecitabine in elderly patients with advanced colorectal cancer (CRC).Fifty-one patients with advanced CRC who were >/= 70 years and considered ineligible for combination chemotherapy received oral capecitabine 1,250 mg/m(2) twice daily on days 1 to 14 every 3 weeks. Patients with a creatinine clearance of 30 to 50 mL/min received a dose of 950 mg/m(2) twice daily.A total of 248 cycles of capecitabine were administered (median, five cycles; range, one to eight cycles). ...
Tópico(s): Chemotherapy-related skin toxicity
2005 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Miguel Ángel Díaz, Marta González‐Vicent, Manuel Ramı́rez, Julián Sevilla, Álvaro Lassaletta, Antonio Pérez‐Martínez, Luís Madero,
Forty-two consecutive pediatric patients with high-risk leukemia who received cord blood (CB) transplantation at the authors’ institution from January 1996 and December 2007 were included in this study. Age ranged from 6 months to 18 years and body weight from 7 to 73 kg. Twenty-nine patients had ALL and 13 AML. Twenty-seven out of 42 patients were transplanted in advanced phase of disease (beyond 2nd CR). For 13 patients the CB transplantation was their second transplant. The median follow-up for ...
Tópico(s): Acute Myeloid Leukemia Research
2009 - Taylor & Francis | Pediatric Hematology and Oncology
Huan Zhang, José Manuel Vicent‐Luna, Shuxia Tao, Sofı́a Calero, R. J. Jiménez Riobóo, M. Luisa Ferrer, Francisco del Monte, Marı́a C. Gutiérrez,
Ionic liquids (ILs) and deep eutectic solvents (DESs) have been lately the solvents of choice in a number of processes because they offer a valid alternative to conventional solvents. Despite main interactions in ILs differ from those in DESs (e.g., electrostatic-type in the former and H-bond-type in the latter), these two neoteric solvents are more closely related that appeared and can be seen as the two sides, the face and the cross, of the same coin. Herein, we hypothesized about a way for transitioning ...
Tópico(s): Electrochemical Analysis and Applications
2022 - American Chemical Society | ACS Sustainable Chemistry & Engineering
Produção Nacional
Revisado por pares
Angela McInerney, Gabriela Tirado‐Conte, Josep Rodés‐Cabau, Francisco Campelo‐Parada, José D. Tafur Soto, Marco Barbanti, Érika Muñoz-García, Mobeena Arif, Diego Lopez, Stefan Toggweiler, Gabriela Veiga, Anna Pyłko, Teresa Sevilla, Miriam Compagnone, Ander Regueiro, Viçent Serra, Manuel Carnero, J. Domínguez, Fernando Rivero, Henrique Barbosa Ribeiro, Leonardo Guimarães, Anthony Matta, Natalia Giraldo Echavarría, Roberto Valvo, Federico Moccetti, Antonio J. Muñoz-García, Javier López‐País, Bruno García del Blanco, Diego Carter Campanha Borges, Éric Dumont, Nieves Gonzalo, Enrico Criscione, Maciej Dąbrowski, Fernándo Alfonso, José M. de la Torre Hernández, Asim N. Cheema, Ignacio J. Amat‐Santos, Francesco Saia, Javier Escaned, Luis Nombela‐Franco,
Background There is a paucity of outcome data on patients who are morbidly obese (MO) undergoing transcatheter aortic valve replacement. We aimed to determine their periprocedural and midterm outcomes and investigate the impact of obesity phenotype. Methods and Results Consecutive patients who are MO (body mass index, ≥40 kg/m2, or ≥35 kg/m2 with obesity-related comorbidities; n=910) with severe aortic stenosis who underwent transcatheter aortic valve replacement in 18 tertiary hospitals were compared ...
Tópico(s): Cardiovascular Function and Risk Factors
2021 - Wiley | Journal of the American Heart Association
Alessandro Caiazzo, Kunal Datta, Junke Jiang, María C. Gélvez‐Rueda, Junyu Li, Riccardo Ollearo, José Manuel Vicent‐Luna, Shuxia Tao, Ferdinand C. Grozema, Martijn M. Wienk, René A. J. Janssen,
Abstract Solution‐processed quasi‐2D perovskites are promising for stable and efficient solar cells because of their superior environmental stability compared to 3D perovskites and tunable optoelectronic properties. Changing the number of inorganic layers ( n ) sandwiched between the organic spacers allows for tuning of the bandgap. However, narrowing the phase distribution around a specific n‐ value is a challenge. In‐situ UV–vis–NIR absorption spectroscopy is used to time‐resolve the crystallization ...
Tópico(s): Conducting polymers and applications
2021 - Wiley | Advanced Energy Materials
Mike Pols, José Manuel Vicent‐Luna, Ivo A. W. Filot, Adri C. T. van Duin, Shuxia Tao,
Halide perovskites make efficient solar cells but suffer from several stability issues. The characterization of these degradation processes is challenging because of the limited spatiotemporal resolution in experiments and the absence of efficient computational methods to study these reactive processes. Here, we present the first reactive force field for molecular dynamics simulations of the phase instability and the defect-induced degradation in CsPbI3. We find that the phase transitions are driven ...
Tópico(s): Solid-state spectroscopy and crystallography
2021 - American Chemical Society | The Journal of Physical Chemistry Letters
José Manuel Vicent‐Luna, Sofia Apergi, Shuxia Tao,
In recent years, metal halide perovskites (MHPs) for optoelectronic applications have attracted the attention of the scientific community due to their outstanding performance. The fundamental understanding of their physicochemical properties is essential for improving their efficiency and stability. Atomistic and molecular simulations have played an essential role in the description of the optoelectronic properties and dynamical behavior of MHPs, respectively. However, the complex interplay of the ...
Tópico(s): Magnetic and transport properties of perovskites and related materials
2021 - American Chemical Society | Journal of Chemical Information and Modeling
Xuan Peng, José Manuel Vicent‐Luna, Qibing Jin,
In view of the increasingly severe global warming and ocean acidification caused by CO2 emissions, we report a new procedure, named "reactive separation", to capture CO2. We used advanced Monte Carlo and molecular dynamics methods to simulate the water–gas shift reaction in single-walled carbon nanotubes. We found that (11,11) carbon nanotubes with a diameter of 0.75 nm have the best ability to capture CO2 generated in the water–gas shift reaction. When the feed water–gas ratio is 1:1, the pressure ...
Tópico(s): Zeolite Catalysis and Synthesis
2021 - American Chemical Society | ACS Applied Materials & Interfaces
Junke Jiang, José Manuel Vicent‐Luna, Shuxia Tao,
Metal halide perovskites (MHPs) are gaining increasing attention as low-cost, high-performance semiconductors for optoelectronics. In particular, their solution processing is compatible with the large-scale manufacturing of thin-film devices, including solar cells and light-emitting diodes. Understanding the coordination chemistry in precursor-solvent solution and atomistic mechanisms of film formation is of great importance for optimizing the optoelectronic properties of the final films. Using the ...
Tópico(s): Quantum Dots Synthesis And Properties
2021 - Elsevier BV | Journal of Energy Chemistry
Xuejun Lu, José Manuel Vicent‐Luna, Sofı́a Calero, Rafael M. Madero‐Castro, Marı́a C. Gutiérrez, M. Luisa Ferrer, Francisco del Monte,
For many years, the performance of Li-ion batteries (LIBs) and supercapacitors (SCs) has relied mainly on two factors, (1) the optimization of electrodes composition and/or structure and (2) the selection of salts or ionic liquids (ILs) matching well with the compositional and/or structural features of electrodes. Solvents included in electrolyte composition have been typically seen as a mere medium where the electrochemically active salts or ILs are dissolved or mixed. More recently, attention has also ...
Tópico(s): Advanced Battery Materials and Technologies
2021 - Elsevier BV | Energy storage materials
Nieves López‐Salas, José Manuel Vicent‐Luna, E. Posada, Silvia Imberti, Rafael M. Madero‐Castro, Sofı́a Calero, Conchi O. Ania, R. J. Jiménez Riobóo, Marı́a C. Gutiérrez, M. Luisa Ferrer, Francisco del Monte,
Aqueous dilutions of deep eutectic solvents (DESs) have lately allowed exploring new and more demanding applications where neat DESs are not able to perform well. However, the use of DES dilutions with nonaqueous hydrogen-bond-forming solvents remains basically unexplored. It is worth noting the obvious interest of using organic solvents in those cases where any reagent or byproduct is nonsoluble, nonmiscible, or unstable in water, the presence of water might alter the reaction kinetics (for instance, ...
Tópico(s): Oxidative Organic Chemistry Reactions
2020 - American Chemical Society | ACS Sustainable Chemistry & Engineering
Xuan Peng, José Manuel Vicent‐Luna, Qibing Jin,
The capture and separation of CF4, C2F6, and SF6 and their mixtures containing nitrogen is a challenging process. To solve this, we propose the use of saccharose coke-based carbons as membranes for the adsorption and separation of these gases. By means of advanced techniques of Monte Carlo and molecular dynamics simulations, we have studied the adsorption and diffusion of CF4, C2F6, and SF6 as well as their mixtures with nitrogen in three HRMC carbon models, namely, CS400, CS1000, and CS1000a. We ...
Tópico(s): Membrane Separation and Gas Transport
2020 - American Chemical Society | ACS Applied Materials & Interfaces
Carmen González-Galán, Azahara Luna‐Triguero, José Manuel Vicent‐Luna, Ana Paula Zaderenko, Andrzej Sławek, Rocío Sánchez‐de‐Armas, Sofı́a Calero,
Tópico(s): Metal-Organic Frameworks: Synthesis and Applications
2020 - Elsevier BV | Chemical Engineering Journal
I. Matito-Martos, Ana Martín-Calvo, Conchi O. Ania, J.B. Parra, José Manuel Vicent‐Luna, Sofı́a Calero,
Ammonia is an important chemical compound used in a wide range of applications. This makes its capture, purification and recovery necessary. We combine experimental and molecular simulation techniques to identify the molecular mechanisms ruling the adsorption of ammonia in pure and high silica zeolites. To reproduce accurately the interaction between ammonia and the zeolites the development of a transferable set of Lennard-Jones parameters was needed. Adsorption isotherms were measured and also ...
Tópico(s): Adsorption and biosorption for pollutant removal
2020 - Elsevier BV | Chemical Engineering Journal
Nieves López‐Salas, José Manuel Vicent‐Luna, Silvia Imberti, E. Posada, María J. Roldán‐Ruiz, Juan A. Anta, Salvador R. G. Balestra, Rafael M. Madero‐Castro, Sofı́a Calero, R. J. Jiménez Riobóo, Marı́a C. Gutiérrez, M. Luisa Ferrer, Francisco del Monte,
Deep eutectic solvents (DESs) are lately expanding their use to more demanding applications upon aqueous dilution thanks to the preservation of the most appealing properties of the original DESs while overcoming some of their most important drawbacks limiting their performance, like viscosity. Both experimental and theoretical works have studied this dilution regime, the so-called "water-in-DES" system, at near-to stoichiometric amounts to the original DES. Herein, we rather studied the high-dilution ...
Tópico(s): Chemical and Physical Properties in Aqueous Solutions
2019 - American Chemical Society | ACS Sustainable Chemistry & Engineering
El trabajo discute algunas implicaciones analíticas de las propuestas de Haldon acerca del «modo tributario de producción» como categoría histórica general, capaz de describir la forma de las relaciones sociales predominantes en las formaciones sociales pre-capitalistas. Desde el momento en que asumimos esta tesis, cada uno de los procesos particulares de emergencia de formaciones tributarias «primarias» debe ser considerado como un caso particular de un evento general: el origen de la sociedad de ...
Tópico(s): Economic and Social Development
2019 - Spanish National Research Council | Hispania
Anqi Liu, Xuan Peng, Qibing Jin, Surendra Jain, José Manuel Vicent‐Luna, Sofı́a Calero, Dongfeng Zhao,
We performed molecular simulations to investigate the adsorption and diffusion of benzene in metal–organic framework Mg-MOF-74. At 300 K and 20 Pa, the saturated loading of benzene reaches 8.2 mmol/g, almost twice of (12,12) single-walled carbon nanotube with a similar pore size, and 93% of the benzene molecules in Mg-MOF-74 can desorb at 390 K. The energy analysis indicates that the van der Waals contribution still dominates 70–80% of the total fluid–wall interaction energy compared with the Coulombic ...
Tópico(s): Industrial Gas Emission Control
2019 - American Chemical Society | ACS Applied Materials & Interfaces
Xuan Peng, José Manuel Vicent‐Luna, Surendra Jain, Qibing Jin, Jayant K. Singh,
The adsorption and diffusion of water in realistic CMK-1, CMK-3, and CMK-5 carbon models at 300 K has been studied via grand canonical Monte Carlo and molecular dynamics simulations. The presence of −COOH and −OH functional groups has been found to be crucial to describe the adsorption process, while the models without functional groups are unable to capture the host–guest interactions. Functional groups were attached in cylindrical shells on the outer walls of CMK models in 2 and 4 cylindrical shells ...
Tópico(s): Zeolite Catalysis and Synthesis
2019 - American Chemical Society | ACS Applied Nano Materials
Azahara Luna‐Triguero, Andrzej Sławek, H.P. Huinink, Thijs J. H. Vlugt, Ali Poursaeidesfahani, José Manuel Vicent‐Luna, Sofı́a Calero,
According to the European Commission, in 2016 the residential sector represented 25.4% of the final energy consumption. Heating and cooling in EU households account for 69.1% of the total energy consumption. The fraction of 84% for heating and cooling is still generated from fossil fuels, and only 16% is generated from renewable energy. To decrease carbon dioxide emissions of fossil fuel consumption, it is crucial to find alternatives to supply the heating and cooling demand. Alternatives such as ...
Tópico(s): Zeolite Catalysis and Synthesis
2019 - American Chemical Society | ACS Applied Nano Materials