Simão Branco‐Neves, Cristiano Soares, Alexandra de Sousa, Viviana Martins, Manuel Azenha, Hernâni Gerós, Fernanda Fidalgo,
Abstract Copper (Cu) is an abundant metal in the environment coming from anthropogenic activities and natural sources that, in excess, easily becomes phytotoxic to most species, being its accumulation in plants considered an environmental threat. This study aimed to compare the physiological and molecular responses of Solanum lycopersicum and its wild counterpart Solanum cheesmaniae to Cu stress. In particular, we wanted to address the hypothesis that S. cheesmaniae is more adapted to Cu stress than ...
Tópico(s): Heavy metals in environment
2017 - Wiley | Food and Energy Security
Produção Nacional
Revisado por pares
Walter de Souza Tavares, Gabriela Ribeiro Pena, Manuel Martín‐Pastor, Francisco Fábio Oliveira de Sousa,
Ellagic acid (EA) has demonstrated remarkable antioxidant and antimicrobial activities. The corn protein zein is a natural biopolymer whose biological and functional properties encourage its use to improve therapeutic nano drug delivery systems. In this study, we aimed to design and characterize EA-loaded zein nanoparticles and to evaluate the impact of nanoencapsulation in the antioxidant and antibacterial properties. The nanoparticles were produced by nanoprecipitation and evaluated in terms of ...
Tópico(s): Bee Products Chemical Analysis
2021 - Elsevier BV | Journal of Molecular Liquids
Produção Nacional
Revisado por pares
Walter S. Tavares, Alberto Gomes Tavares, Francisco J. Otero‐Espinar, Manuel Martín‐Pastor, Francisco Fábio Oliveira de Sousa,
Chitosan/zein films were developed for controlled release of ellagic acid using a central composite design to evaluate the effect of the polymers concentration on the films’ characteristics and its application as a wound bandaging platform. The films’ characteristics were predicted with quadratic models. Responses were found to depend on the composition of the film, with both polymers exerting a significant influence on the resulting thickness and contact angle (p < 0.05). Zein presented a significant ...
Tópico(s): Nanocomposite Films for Food Packaging
2020 - Elsevier BV | Journal of Drug Delivery Science and Technology
Produção Nacional
Revisado por pares
Ramires Alsamir Tibana, Ivo Vieira de Sousa Neto, Nuno Manuel Frade de Sousa, Wellington Martins dos Santos, Jonato Prestes, João Henrique Falk Neto, Fábio Hech Dominski, Michael D. Kennedy, Fabrício Azevedo Voltarelli,
Abstract Background To investigate the time-course effects of a self-regulated training session (performed at an rating perceived exertion of 6/10), all-out session, and a control session on the metabolic, hormonal, and brain derived neurotrophic factor (BDNF) responses in Functional-Fitness (FFT) participants. Methods In a randomized, crossover fashion, eight healthy males (age 28.1 ± 5.4 years old; body mass 77.2 ± 4.4 kg; VO 2max : 52.6 ± 4.6 mL.(kg.min) −1 ; 2000 m rowing test 7.35 ± 0.18 min; 1RM back squat ...
Tópico(s): Cardiovascular and exercise physiology
2022 - BioMed Central | BMC Sports Science Medicine and Rehabilitation
Produção Nacional
Revisado por pares
Michelli Luciana Massolini Laureano, Raúl A. Martins, Nuno Manuel Frade de Sousa, Aristides M. Machado‐Rodrigues, João Valente‐dos‐Santos, Manuel J. Coelho‐e‐Silva,
Objective: to verify if functional fitness (FF) is associated with the annual cost of medication consumption and mood states (MSt) in elderly people. Methods: a cross-sectional study with 229 elderly people aged 65 years or more at Santa Casa de Misericórdia de Coimbra, Portugal. Seniors with physical and psychological limitations were excluded, as well as those using medication that limits performance on the tests. The Senior Fitness Test was used to evaluate FF, and the Profile of Mood States - Short ...
Tópico(s): Balance, Gait, and Falls Prevention
2014 - Brazilian Medical Association | Revista da Associação Médica Brasileira
Produção Nacional
Revisado por pares
Walter de Souza Tavares, Manuel Martín‐Pastor, Alberto Gomes Tavares, Francisco Fábio Oliveira de Sousa,
Ellagic acid (EA) has demonstrated several biological properties, such as antioxidant, antimicrobial, and enzymatic inhibition. Zein and chitosan (CHI) are natural polymers whose biological potential has also gained attention. Therefore, this paper aimed to evaluate the antimicrobial, antioxidant, anticollagenase, and antielastase properties of EA, zein, and chitosan isolated or in combination. The microdilution method was used to assess the minimum inhibitory and bactericide concentrations. The antioxidant ...
Tópico(s): Cynara cardunculus studies
2018 - Wiley | Journal of Food Science
Produção Nacional
Revisado por pares
Francisco Fábio Oliveira de Sousa, Asteria Luzardo‐Álvarez, J. Blanco‐Méndez, Manuel Martín‐Pastor,
Zein is a protein containing a large amount of nonpolar amino acids, which has shown the ability to form aggregates and entrap solutes, such as drugs and amino acids. NMR techniques were used to detect binding interactions and measure affinity between zein and three different drugs: tetracycline, amoxicillin and indomethacin. The release study of zein microparticle formulations containing any of these drugs was confronted with the affinity results, showing a remarkable correlation. The feasible ...
Tópico(s): Force Microscopy Techniques and Applications
2012 - Elsevier BV | International Journal of Pharmaceutics
Produção Nacional
Revisado por pares
Francisco Fábio Oliveira de Sousa, Asteria Luzardo‐Álvarez, J. Blanco‐Méndez, Francisco J. Otero‐Espinar, Manuel Martín‐Pastor, Isabel Sández-Macho,
Zein is a protein based natural biopolymer containing a large amount of nonpolar amino acids, which has shown the ability to form aggregates and entrap solutes, such as drugs and amino acids to form stable protein–drug complexes. In this work, π–A isotherm, NMR, and Dynamic light scattering were used to detect the formation of protein aggregates and the affinity between zein and two different drugs: tetracycline and indomethacin. An effective interaction of zein and the two drugs was evidenced by ...
Tópico(s): Polymer Surface Interaction Studies
2013 - Elsevier BV | European Journal of Pharmaceutics and Biopharmaceutics
Marc de Manuel, Martin Kuhlwilm, Peter Frandsen, Vítor C. Sousa, Tariq Desai, Javier Prado-Martinez, Jessica Hernandez‐Rodriguez, Isabelle Dupanloup, Óscar Lao, Pille Hallast, Joshua M. Schmidt, José María Heredia‐Genestar, Andrea Benazzo, Guido Barbujani, Benjamin M. Peter, Lukas F. K. Kuderna, Ferrán Casals, Samuel Angedakin, Mimi Arandjelovic, Christophe Boesch, Hjalmar S. Kühl, Linda Vigilant, Kevin E. Langergraber, John Novembre, Marta Gut, Marta Gut, Arcadi Navarro, Frands Carlsen, Aida M. Andrés, Hans R. Siegismund, Aylwyn Scally, Laurent Excoffier, Chris Tyler‐Smith, Sergi Castellano, Yali Xue, Christina Hvilsom, Tomás Marquès‐Bonet,
Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that chimpanzee population substructure makes genetic information a good predictor of geographic origin at country and regional scales. Multiple lines of evidence suggest that gene flow occurred from bonobos into the ancestors of central and eastern chimpanzees between 200,000 and 550,000 ...
Tópico(s): Wildlife Ecology and Conservation
2016 - American Association for the Advancement of Science | Science
Produção Nacional
Revisado por pares
Jennifer Thayanne Cavalcante de Araújo, Manuel Martín‐Pastor, Lourdes Pérez, Aurora Pinazo, Francisco Fábio Oliveira de Sousa,
Anacardic acid (AA) has gained interest regarding its extraordinary antimicrobial activity. Nanotechnology based delivery systems are a modern approach to improve both pharmacological and functional properties of therapeutic agents. In this paper we aimed to design and characterize AA loaded-zein nanoparticles and evaluate its antimicrobial efficiency in vitro using microdilution and antibiofilm assays. AA nanoparticles were spherical, stable, with an average size of 381.6 nm and negative ζ potential . ...
Tópico(s): Pickering emulsions and particle stabilization
2021 - Elsevier BV | Journal of Molecular Liquids
Catarina Martins, Ana Amorim‐de‐Sousa, Miguel Faria‐Ribeiro, Jaume Pauné, José Manuel González‐Méijome, António Queirós,
Purpose Contact lenses (CLs) used for myopia control incorporate variable power distribution across the optic zone potentially creating degradation of the high-order aberrations. The present study aims to evaluate the retinal image quality and visual performance in three prototypes of CLs intended to control axial elongation of the eye before they are considered for clinical trials.Methods This is a non-dispensing cross-over, double-blind study where 30 right eyes of myopic subjects worn 3 multifocal ...
Tópico(s): Retinal Diseases and Treatments
2019 - Taylor & Francis | Current Eye Research
Ricardo J. Alves de Sousa, Jorge Ferreira, João Batista Sá de Farias, João Torrão, Daniel Afonso, Manuel A. Martins,
This paper presents the design and project of an innovative concept for a Single Point Incremental Forming (SPIF) Machine. Nowadays, equipment currently available for conducting SPIF result mostly from the adaptation of conventional CNC machine tools that results in a limited range of applications in terms of materials and geometries. There is also a limited market supply of equipment dedicated to Incremental Sheet Forming (ISF), that are costly considering low batches, making it unattractive for ...
Tópico(s): Metallurgy and Material Forming
2014 - Technopress | STRUCTURAL ENGINEERING AND MECHANICS
Produção Nacional
Revisado por pares
Lourdes Pérez, Zakaria Hafidi, Aurora Pinazo, M. Teresa García, Manuel Martín‐Pastor, Francisco Fábio Oliveira de Sousa,
Although cationic surfactants have a remarkable antimicrobial activity, they present an intrinsic toxicity that discourages their usage. In this work novel zein nanoparticles loaded with arginine-phenylalanine-based surfactants are presented. The nanoparticles were loaded with two single polar head (LAM and PNHC12) and two with double amino acid polar head surfactants, arginine-phenylalanine (C12PAM, PANHC12). The formulations were characterized and their stability checked up to 365 days. Furthermore, ...
Tópico(s): Nanocomposite Films for Food Packaging
2023 - Multidisciplinary Digital Publishing Institute | Nanomaterials
Laura Martin, Pablo Pérez‐Merino, Rute J. Macedo-de-Araújo, Ana Amorim‐de‐Sousa, José Manuel González‐Méijome,
Bifocal and multifocal optical devices are intended to get images into focus from objects placed at different distances from the observer. Spectacles, contact lenses, and intraocular lenses can meet the requirements to provide such a solution. Contact lenses provide unique characteristics as a platform for implementing bifocality and multifocality. Compared to spectacles, they are closer to the eye, providing a wider field of view, less distortion, and their use is more consistent as they are not ...
Tópico(s): Ocular Surface and Contact Lens
2020 - Hindawi Publishing Corporation | Journal of Ophthalmology
Benedikt Kersting, Vladimir Ovuka, Vara Prasad Jonnalagadda, Marilyne Sousa, Valeria Bragaglia, Syed Ghazi Sarwat, Manuel Le Gallo, Martin Salinga, Abu Sebastian,
Abstract Phase change memory (PCM) is being actively explored for in-memory computing and neuromorphic systems. The ability of a PCM device to store a continuum of resistance values can be exploited to realize arithmetic operations such as matrix-vector multiplications or to realize the synaptic efficacy in neural networks. However, the resistance variations arising from structural relaxation, 1/f noise, and changes in ambient temperature pose a key challenge. The recently proposed projected PCM ...
Tópico(s): Ferroelectric and Negative Capacitance Devices
2020 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Jéssica Cardoso de Souza, Ramires Alsamir Tibana, Cláudia Regina Cavaglieri, Denis César Leite Vieira, Nuno Manuel Frade de Sousa, Felipe Augusto dos Santos Mendes, Vitor Tajra, Wagner Rodrigues Martins, Darlan Lopes de Farias, Sandor Bálsamo, James W. Navalta, Carmen Sílvia Grubert Campbell, Jonato Prestes,
Abstract Background The aim of the present study was to evaluate the acute effects of resistance exercise (RE) leading to failure and RE that was not to failure on 24 h blood pressure (BP) and heart rate variability (HRV) in sedentary normotensive adult women. Methods Ten women (33.2 ± 5.8 years; 159.3 ± 9.4 cm; 58.0 ±6.4 kg; body fat 28.4 ± 2.8%) randomly underwent three experimental sessions: control (40 minutes of seated rest), RE leading to failure with 3 sets of 10 repetitions maximum (10-RM), and RE not ...
Tópico(s): Sports Performance and Training
2013 - BioMed Central | BMC Cardiovascular Disorders
Produção Nacional
Revisado por pares
Lourena E. Costa, Miguel Á. Chávez‐Fumagalli, Vívian T. Martins, Mariana C. Duarte, Daniela P. Lage, Mayara Ingrid Sousa Lima, Nathália Cristina de Jesus Pereira, Manuel Soto, Carlos Alberto Pereira Tavares, Luíz Ricardo Goulart, Eduardo Antônio Ferraz Coelho,
SUMMARY Two mimotopes of Leishmania infantum identified by phage display were evaluated as vaccine candidates in BALB/c mice against Leishmania amazonensis infection. The epitope-based immunogens, namely B10 and C01, presented as phage-fused peptides; were used without association of a Th1 adjuvant, and they were administered isolated or in combination into animals. Both clones showed a specific production of interferon-gamma (IFN- γ ), interleukin-12 (IL-12) and granulocyte/macrophage colony-stimulating ...
Tópico(s): Trypanosoma species research and implications
2015 - Cambridge University Press | Parasitology
Produção Nacional
Revisado por pares
Jorge Ilha Guimarães, Sérgio Timerman, Germano Emílio Conceição Souza, Ana Paula Qüilici, Maria Margarita Gonzalez, André Guanaes Gomes, Adriana Minor, André Schmidt, Antônio de Pádua Mansur, Caio de Brito Vianna, Dario Magno Batista Ferreira, Edison Ferreira de Paiva, Evandro Tinoco Mesquita, F. Fortea Gil, Flávio Renato Marques, Frederico Carlos de Sousa Arnaud, Hugo Tannus, José Antônio Franchini Ramires, Luis Hargreaves, Marcello Markus Paulista, Manuel F. Canesin, Márcia Regina Fernandes Boaro Martins, Paulo Miranda, Ricardo Tavares de Carvalho, Roberto Kalil Filho, Sílvia Regina Rios Vieira, Tião Viana,
Tópico(s): Intensive Care Unit Cognitive Disorders
2003 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
I Dajti, José Ignacio Valenzuela, L Boccalatte, Nicolas A Gemelli, Dantwan Smith, Nagendra N. Dudi‐Venkata, Hidde M. Kroon, Tarik Sammour, Matthew M. Roberts, D Mitchell, K Lah, A Pearce, Dion Morton, Amanda Dawson, A Drane, Claire Sharpin, Ramesh Nataraja, Maurizio Pacilli, Daniel Cox, Vijayaragavan Muralidharan, Georgina Riddiough, Edmund Clarke, Wael Jamel, Kirby R. Qin, Peter Pockney, Daron Cope, N Egoroff, Natalie Lott, Sven Putnis, S De Robles, Zen Yang Ang, Martin Mitteregger, Stefan Uranitsch, Marjorie Stiegler, Gerald Seitinger, Felix Aigner, D B Lumenta, Sebastian P. Nischwitz, Erika Richtig, Mauro Pau, Petra Srekl-Filzmaier, Nicolas Eibinger, Birgit Michelitsch, Melanie Fediuk, A Papinutti, Geoffrey Seidel, Joseph Kahn, Tina Cohnert, Donna A. Messner, F. Ofner, J Presl, Márta Varga, Michael Weitzendorfer, K. Emmanuel, Alf-Dorian Binder, Marc Zimmermann, S Holawe, Emeka Nkenke, Christoph Grimm, M Kranawetter, Ashrarur Rahman Mitul, Nazmul Islam, Syed S. Karim, Niels Komen, Sven Putnis, S De Robles, Emily Ang, Herbert De Praetere, Tim Tollens, G Schols, C. Smets, Laura Haenen, Jorien Quintens, K Van Belle, Gabriëlle H. van Ramshorst, Piet Pattyn, Liesbeth Desender, Thomas Martens, Dirk Van de Putte, Philip Lerut, Aude Grimonprez, Marcus L.F. Janssen, G. De Smul, P. Wallaert, Jef Van den Eynde, Wouter Oosterlinck, Raf Van den Eynde, An Sermon, A. Boeckxstaens, Anne-Laure Cordonnier, Jeroen De Coster, Joris Jaekers, Constantinus Politis, Marc Miserez, Nicolas Duchateau, Charles de Gheldere, Nicolas Flamey, Piet Pattyn, A Christiano, Benedetta Guidi, A L Minussi, Sílvia Castro, Willy Okoba, F H R Maldonado, Paulo Oliveira, Tiago Antônio Baldasso, Luciano Marques dos Santos, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Laércio Pol Fachin, Tainá Santos Bezerra, Aldo Vieira Barros, A Silva, A L S Leite, Daniela Silvestre, C Carvalho Ferro, M S Araujo, L. M. Lopes, Pâmela dos Santos Bittencourt Damasceno, D H S Araujo, Gustavo Andreazza Laporte, M Salem, Marco Guimarães-Filho, Lucas Souto Nacif, Ronald Luiz Gomes Flumignan, Luís CU Nakano, Danielle Akemi Bergara Kuramoto, A L S Aidar, Mariana Raffo Pereda, R M Correia, Brena Costa Santos, Alzira Alves de Siqueira Carvalho, Jorge Eduardo de Amorim, Henrique Jorge Guedes Neto, Libnah Leal Areias, Álvaro Francisco Lopes de Sousa, Carolina Dutra Queiroz Flumignan, W G Lustre, Doris Hupfeld Moreno, Nathana Prado de Almeida Barros, José Carlos Costa Baptista‐Silva, Leandro Luongo de Matos, L P Kowaski, Marco Aurélio Vamondes Kulcsar, KS Nunes, Marcos F.S. Teixeira, Rafael Leite Nunes, Takeshi Ijichi, N. J. Kim, Ana Beatriz Pontes Marreiro, Bárbara Müller, Joseph Awada, Glauco Baiocchi, Luiz Paulo Kowalski, JG Vartanian, Fabiana B. Makdissi, Samuel Aguiar, Nuno Marques, Genival Barbosa de Carvalho, Tatiana Marques, Emne Ali Abdallah, Charles Edouard Zurstrassen, Jamie Gross, Stênio de Cássio Zéqui, Bruna Tirapelli Gonçalves, Sigrid de Sousa dos Santos, João Pedreira Duprat Neto, Felipe José Fernández Coimbra, Rafael De Cicco, Flávio Roberto Takeda, Ivan Cecconello, Ulysses Ribeiro, A Gatti, R Oliva, C Nardi, Mihail Slavchev, Boyko Atanasov, Nikolay Belev, Angela Dell, David L. Bigam, Khaled Dajani, S Al Riyami, Janet Martin, Davy Cheng, Hua Yang, A Fayad, François Martin Carrier, E. Amzallag, Joannie Desroches, Marie T. Ruel, Natasha Caminsky, Marylise Boutros, J Moon, E. G. C. Wong, Tsafrir Vanounou, Jonathan Pelletier, S Wong, Elie Girsowicz, J Bayne, Daniel I. Obrand, Heather L. Gill, Oren K. Steinmetz, Kenneth MacKenzie, Marie‐Amélie Lukaszewski, Ghader Jamjoum, Philippe Richebé, Olivier Verdonck, S Discepola, Nathalie Godin, M. Idrissi, Vincent Lecluyse, Geneviève Côté, Sebastian Demyttenaere, Richard Garfinkle, Marylise Boutros, A Kouyoumdjian, Marylise Boutros, Sinziana Dumitra, J Moon, E. G. C. Wong, Kosar Khwaja, Lan Luo, Marie‐Amélie Lukaszewski, Heather L. Gill, Gerald J. Berry, Adrienne Liberman, Elie Girsowicz, J Bayne, Daniel I. Obrand, Oren K. Steinmetz, Kenneth MacKenzie, Severin Schmid, Jonathan Spicer, Mehdi Farsi, Jad Abou‐Khalil, Étienne J. Couture, Seyede Momeneh Mohammadi, Hugo Tremblay, Nathalie Gagné, Anne Bergeron, Alexis F. Turgeon, O. Costerousse, David Bellemare, C. Babin, Catherine Blier, M L Wood, Amit Persad, Gary Groot, Hau Pham, Frédérick D’Aragon, Élaine Carbonneau, Maude Bouchard, Marie-Hélène Masse, F Pesant, Jennifer Héroux, Paul J. Karanicolas, Julie Hallet, A Nadler, Avery B. Nathens, M Ko, A Brar, Kelly Mayson, B Kidane, Sadeesh Srinathan, M Escudero, Janette T. Reyes, María Marta Modolo, P Ramirez Nieto, Rodrígo Sepúlveda, A Bolbarán, Andrés Molero‐Chamizo, Isaac Ruiz, Gabriel Reyes, Rafael Salas, Cristóbal Suazo, Rodrigo Muñoz, E Grasset, Martín Inzunza, Nicolás Besser, M J Irarrázaval, Cristián Jarry, Felipe Bellolio, C A Romero Manqui, M Ruiz Esquide, T. Fuentes, José Luis Campos, Carlos J. Pérez-Rivera, Payton Cabrera, Raúl Eduardo Pinilla Morales, Óscar Guevara, LJ Jimenez Ramirez, B G Velasquez Cuasquen, Damián Mora, A Bonilla, Sandra Diaz, E Manrique,
To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the best predictors and used these to create the COVIDsurg Mortality Score (https://covidsurgrisk.app). Our data demonstrates that it is safe to restart a wide ...
Oxford University Press
Tópico(s): Literature, Culture, and Criticism
2003 - | Recherches en anthropologie au Portugal
Laura de Lorenzo, Francisco Merchán, Sandrine Blanchet, Manuel Megı́as, Florian Frugier, Martín Crespi, Carolina Sousa,
Abstract Soil salinity is one of the most significant abiotic stresses for crop plants, including legumes. These plants can establish root symbioses with nitrogen-fixing soil bacteria and are able to grow in nitrogen-poor soils. Medicago truncatula varieties show diverse adaptive responses to environmental conditions, such as saline soils. We have compared the differential root growth of two genotypes of M. truncatula (108-R and Jemalong A17) in response to salt stress. Jemalong A17 is more tolerant ...
Tópico(s): Agronomic Practices and Intercropping Systems
2007 - Oxford University Press | PLANT PHYSIOLOGY
Lourdes Pérez, Adrià Sentís, Zakaria Hafidi, Aurora Pinazo, M. Teresa García, Manuel Martín‐Pastor, Francisco Fábio Oliveira de Sousa,
Cationic surfactants carry antimicrobial activity, based on their interaction and disruption of cell membranes. Nonetheless, their intrinsic toxicity limits their applicability. To overcome this issue, a feasible strategy consists of using solid nanoparticles to improve their delivery. The zein nanoparticles were loaded with four cationic arginine-based surfactants: one single chain Nα-lauroyl-arginine (LAM) and three Gemini surfactants Nα Nω-Bis (Nα-lauroyl-arginine) α, ω-diamide) (C3(LA)2, C6(LA) ...
Tópico(s): Surfactants and Colloidal Systems
2023 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Giacomo Torrisi, João Sousa Luis, Olalla Sànchez‐Sobrado, Rosario Raciti, Manuel J. Mendes, Hugo Águas, Elvira Fortunato, Rodrigo Martins, A. Terrasi,
One of the most promising approaches to produce industrial-compatible Transparent Conducting Materials (TCMs) with excellent characteristics is the fabrication of TCO/metal/TCO multilayers. In this article, we report on the electro-optical properties of a novel high-performing TCO/metal/TCO structure in which the intra-layer is a micro-structured metallic grid instead of a continuous thin film. The grid is obtained by evaporation of Ag through a mask of polystyrene colloidal micro-spheres deposited ...
Tópico(s): ZnO doping and properties
2019 - Elsevier BV | Solar Energy Materials and Solar Cells
Raquel Boia, Paulo A.N. Dias, Joana Martins, Caridad Galindo‐Romero, Inês Aires, Manuel Vidal‐Sanz, Marta Agudo‐Barriuso, Hermínio C. de Sousa, António Francisco Ambrósio, Mara E.M. Braga, Ana Raquel Santiago,
This work reports the development of porous poly (ε-caprolactone) (PCL)-based intraocular implants, prepared by green supercritical carbon dioxide (scCO2) foaming/mixing method (SFM), to produce implants that degrade faster than typical slow-degrading PCL-based implants. The higher porosities and surface areas of these implants led to faster degradation rates at in vitro accelerated alkaline conditions than low porosity/surface area implants prepared by hot melting processing. These porous implants ...
Tópico(s): Neuroscience and Neural Engineering
2019 - Elsevier BV | Journal of Controlled Release
V. Teixeira, Estefane Soares Rodrigues de Sousa, Manuel F. M. Costa, C. Nunes, Lívia Raquel de Oliveira Rosa, Maria João Carvalho, Manuel Collares-Pereira, E. Román, José Á. Martín‐Gago,
Efficient solar photothermal conversion benefits from spectrally selective absorber surfaces. In this paper, a numerical model that allows correlation of the selectivity of the absorbers produced to the collector efficiency is presented. Since magnetron sputtering is a promising method to produce thin, solar selective films, a study of cermet Cr–Cr2O3 and Mo–Al2O3 coatings obtained by this technique in a reactive atmosphere is presented. The multilayered cermets produced have a thickness of approximately ...
Tópico(s): solar cell performance optimization
2001 - Elsevier BV | Thin Solid Films
Marino Vega-Vázquez, Juan Carlos Cobas, Francisco Fábio Oliveira de Sousa, Manuel Martín‐Pastor,
A reverse diffusion filter NMR experiment (Drev) is proposed for the study of small molecules in binding with macromolecules. The filtering efficiency of Drev to eliminate the signals of the macromolecule is shown to be superior to conventional transverse relaxation filters at least for macromolecules containing a significant fraction of flexible residues. The Drev filter was also a useful complement for ligand-based NMR screening in combination with saturation transfer difference experiments.
Tópico(s): Advanced MRI Techniques and Applications
2011 - Wiley | Magnetic Resonance in Chemistry
Produção Nacional
Revisado por pares
Jennifer Thayanne Cavalcante de Araújo, Laís Aragão Lima, Everton Pantoja Vale, Manuel Martín‐Pastor, Ramille Araújo Lima, Paulo Goberlânio de Barros Silva, Francisco Fábio Oliveira de Sousa,
Anacardic acid extracted from cashew nut shells of Anacardium occidentale L has demonstrated important biological activities, such as antibacterial activity against the cariogenic specie Streptococcus mutans. Zein nanoparticles containing anacardic acid (9.375 μg/mL) were evaluated in terms of toxicity and genotoxicity in vivo. The subacute toxicity assay was used to evaluate the cumulative effects of the oral administration of nanoencapsulated anacardic acid at 2.25 and 112.5 μg/kg for 7 days in ...
Tópico(s): Ginkgo biloba and Cashew Applications
2020 - Elsevier BV | Toxicology Reports
Lourdes Vicent, Míriam Juárez, Irene Martín de Miguel, J García, Hugo González‐Saldívar, Vanesa Bruña, Carolina Devesa, Iago Sousa-Casasnovas, Francisco Fernández‐Avilés, Manuel Martínez‐Sellés,
<b><i>Objectives:</i></b> Sacubitril/valsartan was approved recently for the treatment of patients with heart failure and reduced ejection fraction. We present 6 cases of ventricular arrhythmia, that occurred shortly after sacubitril/valsartan initiation, that required drug withdrawal. Other potential triggering factors of electrical storm were ruled out and, from the arrhythmic perspective, all of the patients were stable in the previous year. Our aim is to describe the ...
Tópico(s): Cardiac Arrhythmias and Treatments
2018 - Karger Publishers | Cardiology
Pablo Guisado‐Vasco, María Maravillas Carralón-González, José Aguareles, Eva María Martí-Ballesteros, Mónica Sánchez-Manzano, Daniel Carnevali-Ruiz, Marta García-Coca, Ruth Barrena-Puertas, R. García de Viedma, José Manuel Luque-Pinilla, Gabriel Sotres-Fernández, J.M. Fernández-Sousa, Xavier Erik Luepke-Estefan, José A. López-Martín, José Jimeno,
Abstract Background There is an urgent need for highly efficacious antiviral therapies in immunosuppressed hosts who develop coronavirus disease (COVID-19), with special concern for those affected by hematological malignancies. Case presentation Here, we report the case of a 75-year-old male with chronic lymphocytic leukemia who was deficient in CD19 + CD20 + B-lymphocyte populations due to previous treatment with anti-CD20 monoclonal antibodies. The patient presented with severe COVID-19 pneumonia due ...
Tópico(s): Immune Cell Function and Interaction
2022 - BioMed Central | Journal of Hematology & Oncology
Tiago Pardal, Sofia Messias, Margarida Sousa, Ana S. Reis Machado, C.M. Rangel, Daniela Nunes, Joana V. Pinto, Rodrigo Martins, Manuel Nunes da Ponte,
The electrochemical reduction of carbon dioxide dissolved in a solution of water and ionic liquid as electrolyte, at high-pressure and near room-temperature, is reported. This work describes an electro-deposition strategy for the preparation of copper substrate cathodes, coated with bimetallic zinc–copper films, obtained from deep-eutectic solvents plating baths. The prepared bimetallic cathodes showed electrochemical activity for syngas production in 1-butyl-3-methylimidazolium triflate, with yields ...
Tópico(s): Catalytic Processes in Materials Science
2017 - Elsevier BV | Journal of CO2 Utilization