Produção Nacional
Revisado por pares
Marcelo Cordeiro‐Santos, Bernardino Cláudio de Albuquerque, Rosemary Costa Pinto, Giralcina Pessoa Reis Aguiar, Andrés G. Lescano, João Hugo Abdalla Santos, Maria das Graças Costa Alecrim,
... paper is part of the doctoral thesis of Marcelo Cordeiro dos Santos of Amazonas State University, Amazonas State ...
Tópico(s): Forensic Toxicology and Drug Analysis
2009 - Pan American Health Organization | Revista Panamericana de Salud Pública
Produção Nacional
Revisado por pares
Maria das Graças Gomes Saraiva, Eyde Cristianne Saraiva dos Santos, Valéria Saraceni, Lívia Laura dos Santos Rocha, Rossicléia Lins Monte, Bernardino Cláudio de Albuquerque, Michele de Souza Bastos, Marcelo Cordeiro‐Santos, Wuelton Marcelo Monteiro, Maria Paula Gomes Mourão, Marcus Vinítius de Farias Guerra, Marcus Lacerda,
In the State of Amazonas, particularly in the capital Manaus, meningitis has affected populations of different cultures and social strata over the years. Bacterial meningitis is caused by several different species and represents a major issue of public health importance. The present study reports the meningitis case numbers with different etiologies in Amazonas from January 1976 to December 2012.Since the 1970s, the (currently named) Tropical Medicine Foundation of Doutor Heitor Vieira Dourado [Fundação ...
Tópico(s): Syphilis Diagnosis and Treatment
2015 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
José L. Luque, A. S. Cordeiro, Marcelo E. Oliva,
Examination of 248 adult specimens of whitemouth croaker Micropogonias furnieri from five localities along the Brazilian coast revealed 8735 parasites belonging to 41 metazoan species. Samples from Ceará to Bahia and Rio de Janeiro to Santa Catarina showed a high level of correct assignation (92 and 87%, respectively) and cross assignation ( i.e. almost all specimens misidentified in Ceará were assigned to Bahia and almost all specimens misidentified in Bahia were classified as Ceará), so samples were ...
Tópico(s): Marine and fisheries research
2010 - Wiley | Journal of Fish Biology
Produção Nacional
Revisado por pares
Mateus Saquetti, Ronaldo Canofre, Arthur F. Lorenzon, Fábio Diniz Rossi, José Rodrigo Azambuja, Weverton Cordeiro, Marcelo Caggiani Luizelli,
In this letter, we make a case for in-network intelligence in programmable data planes (PDPs) by taking the first steps toward running distributed Artificial Neural Networks (ANNs) in programmable switches. The main novelty of our research lies in distributing the neurons of an ANN into multiple switches instead of running an entire ANN in a single device. The many advantages of this approach include wider network flow visibility and better resource usage across switches and links. We discuss the ...
Tópico(s): Ferroelectric and Negative Capacitance Devices
2021 - IEEE Communications Society | IEEE Communications Letters
Produção Nacional
Revisado por pares
M S Marques, Marcos Freitas Cordeiro, Marcelo Augusto Germani Marinho, C.O. Vian, Gustavo Richter Vaz, Brunna Suélli de Souza Alves, Rodrigo Desessards Jardim, Mariana Appel Hort, Cristiana Lima Dora, Ana Paula Horn,
Cerebrovascular diseases are currently a major global health problem. Considering the limitations of current therapy, the search for new alternatives for the treatment of these diseases is necessary and, in this context, curcumin, a molecule that has neuroprotective properties already described in the literature. A limiting factor when considering therapies for the nervous tissue is the presence of the blood-brain barrier which stimulates the search for new drug delivery strategies. In this context, ...
Tópico(s): Neurological Disease Mechanisms and Treatments
2020 - Elsevier BV | Brain Research
Produção Nacional
Revisado por pares
Mateus Goulart Alves, Denise Ferreira Gomide Batista, Aldenôra Laísa Paiva de Carvalho Cordeiro, Marcelo Donizeti Silva, Jocilene de Carvalho Miraveti Canova, Maria Célia Barcellos Dalrí,
To elaborate and validate a teaching virtual contemporary object, video-lesson, about resuscitation cardiopulmonary with adult in life support care using automatic external defibrillator in the hospital environment.This is an applied research of techonlogical productions in witch the video-lesson elaboration was according to the methodological trajectory proposed by Fleming, Reynolds and Wallace. The research was accomplished in the Minas Gerais University State and in the Ribeirão Preto Nursing ...
Tópico(s): Healthcare Regulation
2019 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | Revista gaúcha de enfermagem
Produção Nacional
Revisado por pares
Márcia Helena Borges, Suely G. Figueiredo, Felipe da Veiga Leprevost, Maria Elena de Lima, Marta do Nascimento Cordeiro, Marcelo Ribeiro Vasconcelos Diniz, James J. Moresco, Paulo C. Carvalho, John R. Yates,
Tópico(s): Healthcare and Venom Research
2016 - Elsevier BV | Journal of Proteomics
Produção Nacional
Revisado por pares
Renato S. Carreira, Lívia G.M.S. Cordeiro, Marcelo Bernardes, Vanessa Hatje,
Lipid biomarkers (sterols, alcohols and taraxerol) were quantified in 30 surface sediments from the Camamu Bay (CB), NE Brazil, with the aim of evaluating the sources and distribution of organic matter (OM) in a tropical, well-preserved coastal system. The total organic carbon varied in a wide range (0.8–38.3 mg g−1), reflecting distinct patterns of sediment grain size and hydrodynamics at CB. A mean C/N molar ratio of 22.2 ± 5.2 suggests an important allochthonous source of OM. This is confirmed by the ...
Tópico(s): Marine Bivalve and Aquaculture Studies
2015 - Elsevier BV | Estuarine Coastal and Shelf Science
Produção Nacional
Revisado por pares
Hernane Borges de Barros Pereira, Inácio de Sousa Fadigas, Roberto Luiz Souza Monteiro, Adrian Cordeiro, Marcelo A. Moret,
In this paper, we studied density effects in semantic networks constructed from a database of titles of papers published in scientific journals as a parameter to indicate the diversity of concepts in a journal. The proposed method essentially consists of fixing the number of titles for all of the studied scientific journals and analyzing the behavior of the density variation curves with regard to the inclusion of cliques (that is, complete networks associated with the titles). We observed that density ...
Tópico(s): Advanced Text Analysis Techniques
2015 - Elsevier BV | Physica A Statistical Mechanics and its Applications
Produção Nacional
Revisado por pares
Natal Santos da Silva, Mônica da Silva‐Nunes, Rosely S. Malafronte, Maria José Menezes, Rosane R. D’Arcadia, Natália T. Komatsu, Kézia Katiani Gorza Scopel, Érika Martins Braga, Carlos Eugênio Cavasini, José Antônio Cordeiro, Marcelo U. Ferreira,
We describe the epidemiology of malaria in a frontier agricultural settlement in Brazilian Amazonia. We analysed the incidence of slide-confirmed symptomatic infections diagnosed between 2001 and 2006 in a cohort of 531 individuals (2281.53 person-years of follow-up) and parasite prevalence data derived from four cross-sectional surveys. Overall, the incidence rates of Plasmodium vivax and P. falciparum were 20.6/100 and 6.8/100 person-years at risk, respectively, with a marked decline in the incidence ...
Tópico(s): Global Maternal and Child Health
2010 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Produção Nacional
Leninha Valério do Nascimento, Fabiola Stollar, L. B. Tavares, C. E. Cavasini, Irineu Luiz Maia, José Antônio Cordeiro, Marcelo U. Ferreira,
A case-control study to identify the risk factors for toxoplasmic encephalitis (TE) among HIV-infected patients with latent Toxoplasma gondii infection was performed in a teaching hospital in south-eastern Brazil. Although the subjects were all positive for serum IgG antibodies to Toxoplasma, some (the cases) developed TE during routine follow-up at the hospital whereas others (the controls) did not. Adjusted odds ratios (aOR) were estimated by multiple logistic regression after controlling for potential ...
Tópico(s): Mosquito-borne diseases and control
2001 - Maney Publishing | Annals of Tropical Medicine and Parasitology
Lorus J. Milne, Margery J. Milne,
... the following articles citing this article:Diego Garcia Cordeiro Souza, Marcelo Petracco, Ana Paula Ferreira Danin, Maíra Pombo Population ...
Tópico(s): Fish biology, ecology, and behavior
1946 - University of Chicago Press | The American Naturalist
Produção Nacional
Revisado por pares
Eduardo P. Amaral, Sivaranjani Namasivayam, Artur T. L. Queiroz, Eduardo R. Fukutani, Kerry L. Hilligan, Kate Aberman, Logan Fisher, Caio César Barbosa Bomfim, Keith D. Kauffman, J. Arthur Buchanan, Leslie Santuo, Pedro Henrique Gazzinelli-Guimarães, Diego L. Costa, Mariane Araujo Teixeira, Beatriz Barreto‐Duarte, Clarissa Araújo Gurgel Rocha, Monique Freire Santana, Marcelo Cordeiro‐Santos, Daniel L. Barber, Robert J. Wilkinson, Igor Kramnik, Kazuhiko Igarashi, Thomas J. Scriba, Katrin D. Mayer-Barber, Bruno B. Andrade, Alan Sher,
Abstract Oxidative stress triggers ferroptosis, a form of cellular necrosis characterized by iron-dependent lipid peroxidation, and has been implicated in Mycobacterium tuberculosis (Mtb) pathogenesis. We investigated whether Bach1, a transcription factor that represses multiple antioxidant genes, regulates host resistance to Mtb. We found that BACH1 expression is associated clinically with active pulmonary tuberculosis. Bach1 deletion in Mtb-infected mice increased glutathione levels and Gpx4 expression ...
Tópico(s): Tuberculosis Research and Epidemiology
2023 - Nature Portfolio | Nature Microbiology
Produção Nacional
Revisado por pares
Acácio Gonçalves Netto, Erick M. G. Cordeiro, Marcelo Nicolai, Saul Jorge Pinto de Carvalho, R. F. Lopez Ovejero, Caio A. C. G. Brunharo, Maria Imaculada Zucchi, Pedro Jacob Christoffoleti,
Abstract BACKGROUND Digitaria insularis is a weed species that has gained considerable importance in Brazil's soybean production areas that rely on glyphosate‐resistant cultivars. Herbicide‐resistant weed populations of this species have been reported in many regions in Brazil, first in the south, followed by later reports in the north. We hypothesized that the spread of herbicide‐resistant D. insularis is facilitated by movement of agricultural machinery from the southern regions of Brazil. RESULTS ...
Tópico(s): Agronomic Practices and Intercropping Systems
2021 - Wiley | Pest Management Science
Produção Nacional
Revisado por pares
Aline Fusco Fares, Jorge A Fares, Gislaine Fusco Fares, José Antônio Cordeiro, Marcelo Arruda Nakazone, Patrı́cia Maluf Cury,
Discrepancies between clinical and autopsy diagnoses persists worldwide.We evaluated autopsies in a university hospital in order to assess the accuracy of clinical cardiovascular diagnosis compared to postmortem findings.Four hundred nine consecutive autopsies between 2003 and 2006 were analyzed in a tertiary-care hospital in São José do Rio Preto, SP, Brazil. The comparison of clinic-pathological cardiovascular findings was performed using Goldman's discrepancies classification.Autopsy rate at ...
Tópico(s): Forensic Entomology and Diptera Studies
2011 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Jacqueline de Almeida Gonçalves Sachett, Iran Mendonça da Silva, Eliane Campos Alves, Sâmella Silva de Oliveira, Vanderson de Souza Sampaio, Fábio Francesconi Vale, Gustavo Adolfo Sierra Romero, Marcelo Cordeiro‐Santos, Hedylamar Oliveira Marques, Mônica Colombini, Ana Maria Moura‐da‐Silva, Fan Hui Wen, Marcus Lacerda, Wuelton Marcelo Monteiro, Luiz C. L. Ferreira,
Background Secondary bacterial infections from snakebites contribute to the high complication rates that can lead to permanent function loss and disabilities. Although common in endemic areas, routine empirical prophylactic use of antibiotics aiming to prevent secondary infection lacks a clearly defined policy. The aim of this work was to estimate the efficacy of amoxicillin clavulanate for reducing the secondary infection incidence in patients bitten by Bothrops snakes, and, secondarily, identify ...
Tópico(s): Streptococcal Infections and Treatments
2017 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Mariana Araújo‐Pereira, Betânia M. F. Nogueira, Renata Spener-Gomes, Anna Cristina Calçada Carvalho, Flávia Marinho Sant’Anna, Marina C. Figueiredo, Megan Turner, Afrânio Lineu Kritski, Marcelo Cordeiro‐Santos, Valéria C. Rolla, Timothy R. Sterling, Bruno B. Andrade, Alice M S Andrade, Vanessa Nascimento, Juan M. Cubillos-Angulo, Hayna Malta‐Santos, Jéssica Rebouças-Silva, Saulo R N Santos, André Ramos, Pedro Brito, Carolina AranaStanis Schmaltz, Allyson Guimarães Costa, Leandro Sousa Garcia, Brenda K. de Sousa Carvalho, Bruna P. de Loiola, Adriano Gomes-Silva, Francine P Ignácio, Maria Cristina S. Lourenço, Elisângela Silva, Mayla Mello, Alexandra B. Souza, Beatriz Barreto‐Duarte, Michael S. Rocha, Aline Benjamin, Adriana S. R. Moreira, Jamile G. de Oliveira, Solange Cavalcante, Betina Durovni, José Roberto Lapa e Silva,
Tuberculosis (TB) remains a major plague of humanity. People with TB (PWTB) are commonly anemic. Here, we assessed whether the severity of anemia in PWTB prior to anti-TB treatment (ATT) was a risk factor for an unfavorable outcome.
Tópico(s): Clostridium difficile and Clostridium perfringens research
2023 - Elsevier BV | Journal of Infection and Public Health
... Osteoarthritis: A Randomized Double-Blind Pilot Study Nathali Cordeiro Pinto, Marcelo Victor Pires de, Nathalia Lopes Ferreira, Natalia Almeida ...
Tópico(s): Medical and Biological Ozone Research
2017 - Mary Ann Liebert, Inc. | Photomedicine and Laser Surgery
Produção Nacional
Revisado por pares
Hugo C. Castro‐Faria‐Neto, Marco A. Martins, Patrı́cia T. Bozza, Sandra A.C. Perez, A.C.V. Corrêa-da-Silva, M.C.R. Lima, Hermenegildo N. Cruz, Renato S.B. Cordeiro, Marcelo Valle de Sousa, Lauro Morhy,
The pro-inflammatory activity of enterolobin, a haemolytic protein from Enterolobium contortisiliquum seeds, was investigated. In doses ranging from 1 to 20 micrograms/site, enterolobin induced a dose-dependent paw oedema and pleurisy in rats. The effect was apparent after 15 min, peaked at 6 hr and decreased 24 hr after enterolobin was administered. One hour after the intrathoracic injection of enterolobin, the total leukocyte content of the pleural cavity increased significantly, mainly due to ...
Tópico(s): Phytochemicals and Medicinal Plants
1991 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Eduardo P. Amaral, Taylor W. Foreman, Sivaranjani Namasivayam, Kerry L. Hilligan, Keith D. Kauffman, Caio César Barbosa Bomfim, Diego L. Costa, Beatriz Barreto‐Duarte, Clarissa Araújo Gurgel Rocha, Monique Freire Santana, Marcelo Cordeiro‐Santos, Elsa Du Bruyn, Catherine Riou, Kate Aberman, Robert J. Wilkinson, Daniel L. Barber, Katrin D. Mayer-Barber, Bruno B. Andrade, Alan Sher,
Cellular necrosis during Mycobacterium tuberculosis (Mtb) infection promotes both immunopathology and bacterial dissemination. Glutathione peroxidase-4 (Gpx4) is an enzyme that plays a critical role in preventing iron-dependent lipid peroxidation-mediated cell death (ferroptosis), a process previously implicated in the necrotic pathology seen in Mtb-infected mice. Here, we document altered GPX4 expression, glutathione levels, and lipid peroxidation in patients with active tuberculosis and assess the ...
Tópico(s): RNA modifications and cancer
2022 - Rockefeller University Press | The Journal of Experimental Medicine
Produção Nacional
Revisado por pares
Izabella Picinin Safe, Eduardo P. Amaral, Mariana Araújo‐Pereira, Marcus Lacerda, Vitoria Silva Printes, Alexandra B. Souza, Francisco Beraldi‐Magalhães, Wuelton Marcelo Monteiro, Vanderson de Souza Sampaio, Beatriz Barreto‐Duarte, Alice M S Andrade, Renata Spener-Gomes, Allyson Guimarães Costa, Marcelo Cordeiro‐Santos, Bruno B. Andrade,
Tuberculosis (TB) still causes significant morbidity and mortality worldwide, especially in persons living with human immunodeficiency virus (HIV). This disease is hallmarked by persistent oxidative stress and systemic inflammation. N-acetylcysteine (NAC), a glutathione (GSH) precursor, has been shown in experimental models to limit Mycobacterium tuberculosis infection and disease both by suppression of the host oxidative response and through direct antimicrobial activity. In a recent phase II randomized ...
Tópico(s): Vitamin D Research Studies
2021 - Frontiers Media | Frontiers in Immunology
Produção Nacional
Revisado por pares
María B. Arriaga, Michael S. Rocha, Betânia M. F. Nogueira, Vanessa Nascimento, Mariana Araújo‐Pereira, Alexandra B. Souza, Alice M S Andrade, Allyson Guimarães Costa, Adriano Gomes-Silva, Elisângela Silva, Marina C. Figueiredo, Megan Turner, Betina Durovni, José Roberto Lapa e Silva, Afrânio Lineu Kritski, Solange Cavalcante, Valéria C. Rolla, Marcelo Cordeiro‐Santos, Timothy R. Sterling, Bruno B. Andrade,
It is unknown whether dysglycemia is associated with Mycobacterium tuberculosis transmission.We assessed epidemiological and clinical characteristics of patients with culture-confirmed pulmonary tuberculosis and their close contacts, enrolled in a multicenter prospective cohort in Brazil. Contacts were investigated at baseline and 6 months after enrollment. QuantiFERON positivity at baseline and conversion (from negative to positive at month 6) were compared between subgroups of contacts according ...
Tópico(s): Pneumonia and Respiratory Infections
2021 - Oxford University Press | The Journal of Infectious Diseases
Produção Nacional
Revisado por pares
Beatriz Barreto‐Duarte, Mariana Araújo‐Pereira, Betânia M. F. Nogueira, Luciana Fonseca Sobral, Moreno S. Rodrigues, Artur T. L. Queiroz, Michael S. Rocha, Vanessa Nascimento, Alexandra B. Souza, Marcelo Cordeiro‐Santos, Afrânio Lineu Kritski, Timothy R. Sterling, María B. Arriaga, Bruno B. Andrade,
Approximately 1.4 million people die annually worldwide from tuberculosis. Large epidemiologic studies can identify determinants of unfavorable clinical outcomes according to age, which can guide public health policy implementation and clinical management to improve outcomes. We obtained data from the national tuberculosis case registry; data were reported to the Brazilian National Program (SINAN) between 2010 and 2019. Clinical and epidemiologic variables were compared between age groups (child: < ...
Tópico(s): Chronic Disease Management Strategies
2021 - Frontiers Media | Frontiers in Medicine
Produção Nacional
Revisado por pares
Lauren Peetluk, Peter F. Rebeiro, Felipe Ridolfi, Bruno B. Andrade, Marcelo Cordeiro‐Santos, Afrânio Lineu Kritski, Betina Durovni, Solange Calvacante, Marina C. Figueiredo, David W. Haas, Dandan Liu, Valéria C. Rolla, Timothy R. Sterling, Renata Spener-Gomes, Alexandra B. Souza, Jaquelane Silva Jesus, Aline Benjamin, Flávia Marinho Sant’Anna, Francine P Ignácio, Maria Cristina S. Lourenço, Adriano Gomes-Silva, Jamile G. de Oliveira, Adriana S. R. Moreira, Anna Cristina Calçada Carvalho, Elisângela Silva, Mayla Mello, Michael S. Rocha, Betânia M. F. Nogueira, Vanessa Nascimento, Saulo Nery, Alice M S Andrade, Hayna Malta‐Santos, Jéssica Rebouças-Silva, André Ramos, Sayonara Melo, Juan M. Cubillos-Angulo, Laíse de Moraes,
Abstract Background Despite widespread availability of curative therapy, tuberculosis (TB) treatment outcomes remain suboptimal. Clinical prediction models can inform treatment strategies to improve outcomes. Using baseline clinical data, we developed a prediction model for unsuccessful TB treatment outcome and evaluated the incremental value of human immunodeficiency virus (HIV)–related severity and isoniazid acetylator status. Methods Data originated from the Regional Prospective Observational Research ...
Tópico(s): Machine Learning in Healthcare
2021 - Oxford University Press | Clinical Infectious Diseases
Produção Nacional
Revisado por pares
María B. Arriaga, Mariana Araújo‐Pereira, Beatriz Barreto‐Duarte, Betânia M. F. Nogueira, Maria Vitória C.N.S. Freire, Artur T. L. Queiroz, Moreno S. Rodrigues, Michael S. Rocha, Alexandra B. Souza, Renata Spener-Gomes, Anna Cristina Calçada Carvalho, Marina C. Figueiredo, Megan Turner, Betina Durovni, José Roberto Lapa e Silva, Afrânio Lineu Kritski, Solange Cavalcante, Valéria C. Rolla, Marcelo Cordeiro‐Santos, Timothy R. Sterling, Bruno B. Andrade, Alice M S Andrade, Vanessa Nascimento, Hayna Malta‐Santos, Jéssica Rebouças-Silva, Allyson Guimarães Costa, Jaquelane Silva, Jamile G. de Oliveira, Aline Benjamin, Adriano Gomes-Silva, Flávia Marinho Sant’Anna, Francine P Ignácio, Maria Cristina S. Lourenço, Elisângela Silva, Adriana S. R. Moreira, Mayla Mello,
It is unclear whether diabetes or prediabetes affects unfavorable treatment outcomes and death in people with tuberculosis (PWTB).
Tópico(s): Diagnosis and treatment of tuberculosis
2021 - Oxford University Press | The Journal of Infectious Diseases
Produção Nacional
Revisado por pares
Izabella Picinin Safe, Marcus Lacerda, Vitoria Silva Printes, Adriana Ferreira Praia Marins, Amanda Lia Rebelo Rabelo, Amanda Araújo Costa, Michel Araújo Tavares, Jaquelane Silva Jesus, Alexandra B. Souza, Francisco Beraldi‐Magalhães, Cynthia Pessoa Neves, Wuelton Marcelo Monteiro, Vanderson de Souza Sampaio, Eduardo P. Amaral, Renata Spener Gomes, Bruno B. Andrade, Marcelo Cordeiro‐Santos,
Despite the availability of effective antimicrobials, tuberculosis (TB) is still a serious health threat. Mortality is even higher in people living with HIV who are diagnosed with TB. New therapies are needed to shorten the time required to cure TB and decrease fatality rates in this population. N-acetylcysteine (NAC) is a glutathione precursor and has shown recently in experimental setting to present in vitro and in vivo anti-mycobacterial activity. We test the hypothesis that NAC is safe, well tolerated ...
Tópico(s): Pregnancy and Medication Impact
2020 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Adam Penn‐Nicholson, Stanley Kimbung Mbandi, Ethan Thompson, Simon C. Mendelsohn, Sara Suliman, Novel N. Chegou, Stephanus T. Malherbe, Fatoumatta Darboe, Mzwandile Erasmus, Willem A. Hanekom, Nicole Bilek, Michelle Fisher, Stefan H. E. Kaufmann, Jill Winter, Melissa Murphy, Robin Wood, Carl Morrow, Ildiko Van Rhijn, Branch Moody, Megan Murray, Bruno B. Andrade, Timothy R. Sterling, Jayne S. Sutherland, Kogieleum Naidoo, Nesri Padayatchi, Gerhard Walzl, Mark Hatherill, Daniel E. Zak, Thomas J. Scriba, Fazlin Kafaar, Leslie Workman, Humphrey Mulenga, E. Jane Hughes, Onke Xasa, Ashley Veldsman, Yolundi Cloete, Deborah Abrahams, Sizulu Moyo, Sebastian Gelderbloem, Michèle Tameris, Hennie Geldenhuys, Rodney Ehrlich, Suzanne Verver, Larry Geiter, Gillian F. Black, Gian van der Spuy, Kim Stanley, Magdalena Kriel, Nelita du Plessis, Nonhlanhla Nene, Teri Roberts, Léanie Kleynhans, Andrea Gutschmidt, Bronwyn Smith, André G. Loxton, Gerard Tromp, David L. Tabb, Tom H. M. Ottenhoff, Michèl R. Klein, Mariëlle C. Haks, Kees L. M. C. Franken, Annemieke Geluk, Krista E. van Meijgaarden, Simone A. Joosten, W. Henry Boom, Bonnie Thiel, Harriet Mayanja‐Kizza, Moses Joloba, Sarah Zalwango, Mary Nsereko, Brenda Okwera, Hussein Kisingo, Shreemanta K. Parida, Robert Golinski, Jeroen Maertzdorf, January Weiner, Mark Z. Jacobson, Hazel M. Dockrell, Steven G. Smith, Patricia Gorak‐Stolinska, Yun‐Gyoung Hur, Maeve K. Lalor, Ji‐Sook Lee, Amelia C. Crampin, Neil French, Bagrey Ngwira, Anne Ben‐Smith, Kate E. Watkins, Lyn Ambrose, Felanji Simukonda, Hazzie Mvula, Femia Chilongo, Jacky Saul, Keith Branson, Hassan Mahomed, E. Jane Hughes, Onke Xasa, Ashley Veldsman, Katrina Downing, Humphrey Mulenga, Bernd Abel, Mark Bowmaker, Benjamin M. Kagina, William Kwong Chung, Jerry Sadoff, Donata Sizemore, Srinivasan Ramachandran, Lew Barker, Michael J. Brennan, Frank Weichold, Stefanie Müller, Larry Geiter, Desta Kassa, Almaz Abebe, Tsehayenesh Mesele, Belete Tegbaru, Debbie van Baarle, Frank Miedema, Rawleigh Howe, Adane Mihret, Abraham Aseffa, Yonas Bekele, Rachel Iwnetu, Mesfin Tafesse, Lawrence Yamuah, Martin O. C. Ota, Philip C. Hill, Richard A. Adegbola, Tumani Corrah, Martín Antonio, Toyin Togun, Ifedayo Adetifa, Simon Donkor, Peter Andersen, Ida Rosenkrands, Mark Doherty, Karin Weldingh, Gary K. Schoolnik, Gregory Dolganov, Trần Thị Thanh Vân, Denis Arendsen, Hadn Africa, Veronica Baartman, Elizabeth Filander, Cynthia Gwintsa, Simbarashe Mabwe, Lebohang Makhethe, Miriam Moses, Raida Onrust, Michele van Rooyen, Marcia Steyn, Habibullah Valley, Petri Ahlers, Gian van der Spuy, Ilana van Rensburg, Hygon Mutavhatsindi, Portia M. Manngo, Kim Stanley, Andriëtte Hiemstra, Shirley McAnda, Joseph Mendy, Awa Gindeh, Georgetta Mbayo, Ebrima Trawally, Olumuyiwa Owolabi, Harriet Mayanja‐Kizza, Mary Nsereko, Anna-Rita Namuganga, Saudah Nambiru Kizito, Adane Mihret, Sosina Ayalew, Rawleigh Howe, Azab Tarekegne, Bamlak Tessema, Emmanuel Nepolo, Joseph Sheehama, Gunar Günther, Azaria Diergaardt, Uapa Pazvakavambwa, Hazel M. Dockrell, Tom H. M. Ottenhoff, Elisa M. Tjon Kon Fat, Shannon Herdigein, Paul L. A. M. Corstjens, Annemieke Geluk, Magdalena Kriel, Gian van der Spuy, André G. Loxton, Kim Stanley, Belinda Kriel, Leigh A. Kotzé, Dolapo Olaitan Awoniyi, Elizna Maasdorp, Olumuyiwa Owolabi, Abdou K. Sillah, Joseph Mendy, Awa Gindeh, Simon Donkor, Toyin Togun, Martin O. C. Ota, Harriet Mayanja‐Kizza, Anna Ritah Namuganga, Grace Muzanye, Mary Nsereko, Pierre Peters, Marieta van der Vyver, Faustina N. Amutenya, Josefina N. Nelongo, Lidia Monye, Jacob Sheehama, Scholastica Iipinge, Amelia C. Crampin, Felanji Simukonda, Alemayehu Amberbir, Femia Chilongo, Rein M. G. J. Houben, Desta Kassa, Atsbeha Gebrezgeabher, Getnet Mesfin, Yohannes Belay, Gebremedhin Gebremichael, Yodit Alemayehu, Rawleigh Howe, Adane Mihret, Yonas Bekele, Bamlak Tessema, Lawrence Yamuah, Tom H. M. Ottenhoff, Annemieke Geluk, Kees L. M. C. Franken, Paul L. A. M. Corstjens, Elisa M. Tjon Kon Fat, Claudia J. de Dood, Jolien J. van der Ploeg-van Schip, Ida Rosenkrands, Claus Aagaard, Maria M. Esterhuyse, Jacqueline M. Cliff, Hazel M. Dockrell, Juan M. Cubillos-Angulo, Kiyoshi F. Fukutani, L. Paixão, Ricardo Khouri, Sayonara Melo, Alice Oliveira Andrade, Jéssica Rebouças-Silva, Hayna Malta, Artur T. L. Queiroz, Valeria C. Rolla, Solange Cavalcante, Betina Durovni, Marcelo Cordeiro‐Santos, Afrânio Lineu Kritski, José Roberto Lapa e Silva, Marina C. Figueiredo, Kattya López Tamara, Kattya López Tamara, Segundo R. León, Leonid Lecca, Dhineshree Govender, Razia Hassan-Moosa, Anushka Naidoo, Rochelle Adams, Natasha Samsunder, Lara Lewis,
Abstract Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature, RISK6, for multiple applications: identifying individuals at risk of incident disease, as a screening test for subclinical or clinical tuberculosis, and for monitoring tuberculosis treatment. RISK6 utility was validated by blind prediction using quantitative real-time (qRT) PCR in seven independent cohorts. Prognostic ...
Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
María B. Arriaga, Gustavo Amorim, Artur T. L. Queiroz, Moreno S. Rodrigues, Mariana Araújo‐Pereira, Betânia M. F. Nogueira, Alexandra B. Souza, Michael S. Rocha, Aline Benjamin, Adriana S. R. Moreira, Jamile G. de Oliveira, Marina C. Figueiredo, Megan Turner, Kleydson Alves, Betina Durovni, José Roberto Lapa e Silva, Afrânio Lineu Kritski, Solange Cavalcante, Valéria C. Rolla, Marcelo Cordeiro‐Santos, Timothy R. Sterling, Bruno B. Andrade,
BackgroundA major goal of tuberculosis (TB) epidemiological studies is to obtain results that can be generalized to the larger population with TB. The ability to extrapolate findings on the determinants of TB treatment outcomes is also important.MethodsWe compared baseline clinical and demographic characteristics and determinants of anti-TB treatment outcomes between persons enrolled in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort between June 2015 and June ...
Tópico(s): Mycobacterium research and diagnosis
2020 - Elsevier BV | International Journal of Infectious Diseases
Produção Nacional
Revisado por pares
Anete Trajman, Maria F. Wakoff-Pereira, Jonas Ramos-Silva, Marcelo Cordeiro‐Santos, Maria de Fátima Pessoa Militão de Albuquerque, Philip C. Hill, Dick Menzies,
Tuberculosis elimination requires treatment of latently infected high-risk persons, such as contacts of index cases. Identification and referral of tuberculosis contacts for investigation are major barriers in the contact cascade-of-care. These tasks rely heavily on auxiliary primary healthcare workers in many low- and middle-income countries. We aimed to understand their knowledge, attitudes and practices (KAP) regarding contact investigation in Brazil.We conducted a cross-sectional KAP survey on ...
Tópico(s): Pneumonia and Respiratory Infections
2019 - BioMed Central | BMC Health Services Research
Produção Nacional
Revisado por pares
Márcia M. C. Ferreira, Cynthia Pessoa Neves, Alexandra B. Souza, Francisco Beraldi‐Magalhães, Giovanni Battista Migliori, Afrânio Lineu Kritski, Marcelo Cordeiro‐Santos,
To identify factors predictive of mortality in patients admitted to the ICU with tuberculosis (TB)/HIV coinfection in the Manaus, Amazon Region.This was a retrospective cohort study of TB/HIV coinfected patients over 18 years of age who were admitted to an ICU in the city of Manaus, Brazil, between January of 2011 and December of 2014. Sociodemographic, clinical, and laboratory variables were assessed. To identify factors predictive of mortality, we employed a Cox proportional hazards model.During ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2018 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia