Cristina de Carvalho Nicacio, Marcelo González Della Valle, Paula Padula, Ewa Björling, Alexander Plyusnin, Åke Lundkvist,
ABSTRACT Hantaviruses are rodent-borne agents that cause hemorrhagic fever with renal syndrome or hantavirus pulmonary syndrome in humans. The nucleocapsid protein (N) is relatively conserved among hantaviruses and highly immunogenic in both laboratory animals and humans, and it has been shown to induce efficient protective immunity in animal models. To investigate the ability of recombinant N (rN) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala ( ...
Tópico(s): Fire effects on ecosystems
2002 - American Society for Microbiology | Journal of Virology

Manoel A. Uchôa-Fernandes, Claudenir Simões Caires, José Nicácio, Marcelo Duarte,
This paper presents a survey of the insects that feed on fruits of Psittacanthus Martius (Santalales: Loranthaceae), a hemiparasitic mistletoe genus that infects trees in Brazil and other neotropical countries. The aim of the study was to identify candidate insects for biological control of Psittacanthus mistletoes. Unripe and mature fruits were collected in several localities of Cerrado, bordering South Pantanal, Southwestern Brazil, from 29 Apr 1998 to 30 Jul 2000. A total of 24,710 fruits (54 samples) ...
Tópico(s): Insect-Plant Interactions and Control
2012 - Florida Entomological Society | Florida Entomologist

Flávia Nicácio Viana, Marcelo Moura Chaves, Samuel Henrique Kamphorst, Antônio Teixeira do Amaral Júnior, Valter Jário de Lima, Jhean Torres Leite, Katia Fabiane Medeiros Schmidt, Uéliton Alves de Oliveira, Danielle Leal Lamêgo, Jacymara Lopes Pereira, Guilherme Ferreira Pena, Henrique Duarte Vieira, Jurandi Gonçalves de Oliveira, Rogério Figueiredo Daher, Eliemar Campostrini, Ricardo Bressan‐Smith,
This study aimed to identify the genetic control of morphological, water status, and root traits in four inbred lines and their pre-selected hybrid combinations of popcorn, and to identify the best parents and hybrids. The plants were grown under greenhouse conditions, and with two water conditions—water-stressed (WS) and well-watered (WW). We evaluated shoot biomass (SB), whole plant leaf area (WPLA), chlorophyll content, carbon isotope discrimination, net CO2 assimilation rate, the stomatal conductance, ...
Tópico(s): Plant Stress Responses and Tolerance
2022 - Multidisciplinary Digital Publishing Institute | Agronomy

Camilla V.N.S. Silva, Jéssica Andréia Pereira Barbosa, Milena Sales Ferraz, Nicácio H. Silva, N Honda, Marcelo Montenegro Rabello, Marcelo Zaldini Hernandes, Beatriz Pinheiro Bezerra, Isabella Macário Ferro Cavalcanti, Alejandro Pedro Ayala, NOEMIA P.S. SANTOS, Nereide Stela Santos-Magalhães,
In this pioneer study, 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) was used to improve the solubility of the diffractaic acid (DA) via inclusion complex (DA:HP-β-CD). Subsequently, DA:HP-β-CD was incorporated into poly-ε-caprolactone (PCL) microspheres (DA:HP-β-CD-MS). Microspheres containing DA (DA-MS) or DA:HP-β-CD (DA:HP-β-CD-MS) were prepared using the multiple W/O/W emulsion-solvent evaporation technique. The phase-solubility diagram of DA in HP-β-CD (10–50 mM) showed an AL type curve with a stability ...
Tópico(s): Nanoparticle-Based Drug Delivery
2016 - Elsevier BV | International Journal of Biological Macromolecules

Igor Santana de Melo, Amanda Larissa Dias Pacheco, Yngrid Mickaelli Oliveira dos Santos, Laura Mello Figueiredo, Dannyele Cynthia Santos Pimentel Nicácio, Léia Cardoso-Sousa, Marcelo Duzzioni, Daniel Leite Góes Gitaí, Cristiane Queixa Tilelli, Robinson Sabino‐Silva, Olagide Wagner de Castro,
Tópico(s): Pharmacological Effects and Toxicity Studies
2020 - Springer Science+Business Media | Molecular Neurobiology

José Maria Soares, José Gomes, Marcelo Rodrigues dos Anjos, Josianne Nicácio Silveira, Flávia Beatriz Custódio, Maria Beatriz Abreu Glória,
The objective of this study was to quantify total mercury in highly popular Amazonian fish pacu, curimatã, jaraqui, and sardinha from the Madeira River and to estimate the exposure to methylmercury from fish consumption. The samples were obtained from two locations - Puruzinho Igarapé and Santa Rosa - near Humaitá, Amazonia, Brazil in two seasons of 2015 (high and low waters). The fish were identified, weighed and measured, and lipids were quantified. Total mercury was determined by gold amalgamation- ...
Tópico(s): Fish biology, ecology, and behavior
2018 - Elsevier BV | Food Research International

Yohan Vianna de Almeida, F. Nicacio, Marcelo F. Santos,
On its own, the invariance properties of Markovian master equations have mostly played a mathematical or computational role in the evaluation of quantum open system dynamics. Because all forms of the equation lead to the same time evolution for the state of the system, the fixation of a particular form has only gained physical meaning when correlated with additional information such as in the evolution of quantum trajectories or the study of decoherence-free subspaces. Here, we show that these symmetry ...
Tópico(s): Quantum many-body systems
2024 - American Physical Society | Physical Review Research

Nadejda de Azevedo Nóbrega, Sheyla Mara de Almeida Ribeiro, Eugênia C. Pereira, Marcelo Pinto Marcelli, Mônica Cristina Barroso Martins, Emerson Peter da Silva Falcão, Norma Buarque de Gusmão, Nicácio Henrique da Silva,
A utilização de metabólitos secundários obtidos de líquens, na indústria farmacêutica, de cosmético, têxtil e de alimentos deve ser criteriosa, visto que a extração e isolamento desses metabólitos requerem uma grande quantidade de biomassa dificilmente renovável, devido ao crescimento lento do líquen. Atualmente, é possível obter substâncias liquênicas tanto por cultivo de tecidos, como por imobilizações celulares e enzimáticas, a partir do talo in natura, utilizando pequena quantidade de material ...
Tópico(s): Mycorrhizal Fungi and Plant Interactions
2012 - Sociedade Botânica do Brasil | Acta Botanica Brasilica

Amanda Larissa Dias Pacheco, Igor Santana de Melo, Fernanda Maria Araújo de Souza, Dannyele Cynthia Santos Pimentel Nicácio, Jucilene Freitas-Santos, Yngrid Mickaelli Oliveira dos Santos, Maisa de Araújo Costa, Cibelle de Melo Bastos Cavalcante, José Gomes dos Santos Neto, Daniel Leite Góes Gitaí, Robinson Sabino‐Silva, Cláudio Torres de Miranda, Alexandre Urban Borbely, Marcelo Duzzioni, Ashok K. Shetty, Olagide Wagner de Castro,
Crack users suffer the effects of cocaine present in the drug and the action of other active compounds from its pyrolysis. An emergent fact is an increase in the number of pregnant crack cocaine users. Studies suggest that crack cocaine and its metabolites cross the placenta, promoting premature birth, fever, irritability, sweating, and seizures in the early months of life. In children, the effects of crack cocaine have been associated with cognitive deficits, difficulty in verbalization, aggressiveness, ...
Tópico(s): Cannabis and Cannabinoid Research
2021 - Elsevier BV | European Neuropsychopharmacology

Amanda Káren Alves Pereira, Eduarda Canedo Nogueira, Emilayne Nicácio Dias Brito, Marcelo Gomes de Almeida, Samila Carla da Silva Nascimento, Sara Claudino dos Santos,
Introdução: A epilepsia é uma alteração crônica com modificações das funções cerebrais, podendo levar à perda da consciência e apresenta crises epilépticas parciais ou focais. Existem diferentes etiologias para a epilepsia, caracterizando um tratamento variado de acordo com a particularidade do indivíduo, o que acentua a polifarmácia. Objetivo: Avaliar a polifarmácia relacionada ao tratamento da epilepsia na rede pública brasileira, reconhecendo o uso exacerbado ou inapropriado de medicações. Metodologia: ...
Tópico(s): Epilepsy research and treatment
2022 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development
Rodolpho Ferreira Lima Vilela, Stefannie Lopes De Freitas, Dannyele Cynthia Santos Pimentel Nicácio, Maria Clara Cavalcanti Campêlo, Marcelo Marotta Araújo, Kayo Costa Alves, André Coelho Lopes,
Dysfunction of the temporomandibular joint (TMJ) can be caused by several factors, including malocclusion, with surgical treatment indicated in specific cases. The orthognathic surgery must be planned correctly, since technical variations, stability in fixation, and incorrect positioning of the condyle may be a pre-disposing factor for bone resorption. Condylar resorption in the TMJ is a pathology that affects female patients with malocclusion, such as Class II skeletal malocclusion, with or without ...
Tópico(s): Facial Trauma and Fracture Management
2018 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology

Marcelo R. de Amorim, Camila de Souza Barbosa, Tiago Antunes Paz, Laura P. Ióca, Karen de Jesus Nicácio, Lucianne Ferreira Paes de Oliveira, Mirian Oliveira Goulart, Julia M. Paulino, Mateus Oliveira da Cruz, Antônio G. Ferreira, Maysa Furlan, Simone Possedente de Lira, Raquel Alves dos Santos, André Rodrigues, Rafael V. C. Guido, Roberto G. S. Berlinck,
Bioassay-guided investigation of the EtOAc-soluble extract of a culture of the marine-derived fungus Peroneutypa sp. M16 led to the isolation of seven new polyketide- and terpenoid-derived metabolites (1, 2, 4–8), along with known polyketides (3, 9–13). Structures of compounds 1, 2, and 4–8 were established by analysis of spectroscopic data. Absolute configurations of compounds 1, 2, 4, 6, 7, and 8 were determined by the comparison of experimental ECD spectra with calculated CD data. Compound 5 exhibited ...
Tópico(s): Plant Pathogens and Fungal Diseases
2023 - American Chemical Society | Journal of Natural Products

Emilayne Nicácio Dias Brito, Bárbara Queiroz de Figueiredo, Diego Nunes Souto, Júlia Fernandes Nogueira, Ana Luísa de Castro Melo, Iorrane Tavares da Silva, Iuri Pimenta Oliveira, Marcelo Gomes de Almeida,
Introdução: Inteligência Artificial (IA) é um ramo da ciência da computação que se propõe a desenvolver sistemas que simulem a capacidade humana de percepção de um problema, identificando seus componentes para, com isso, resolver problemas e propor/tomar decisões. Objetivo: ampliar conhecimentos e categorizar aplicações do uso da IA para o diagnóstico, tratamento e prognóstico de doenças neurodegenerativas, uma vez que, atualmente, seu uso se torna amplamente aplicável e essencial para contornar ...
Tópico(s): Artificial Intelligence in Healthcare
2021 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development
Ivankleison Lima Silva, Stênyo Wanderley Tavares, Emerson Nicácio Medeiros, Edgard Norões Rodrigues da Matta, Sílvia Amélia Scudeler Vedovello, Marcelo de Castro Meneghim,
Tópico(s): Temporomandibular Joint Disorders
2018 - | Orthodontic Science and Practice

Mariana Groke Marques, Flávia Regina Oliveira de Barros, Marcelo Demarchi Goissis, Paulo Varoni Cavalcanti, A. C. Nicacio, Weber Beringui Feitosa, Mayra Elena Ortiz D’Ávila Assumpção, J. A. Visintin,
The aim of this study was to evaluate the efficiency of a low oxygen tension atmosphere (5% CO2, 5% O2, and 90% N2) on swine oocyte maturation in chemically defined media or when supplemented with porcine follicular fluid (PFF). Briefly, oocytes were in vitro matured for 44 h in TCM-199 with 10% PFF or 0.1% PVA added, under a low oxygen tension atmosphere or a normal oxygen tension atmosphere (5% CO2 in air, approximate 20% O2). At 0 and 44 h of maturation, cumulus oophorus cells were removed. To evaluate ...
Tópico(s): Animal Genetics and Reproduction
2008 - CSIRO Publishing | Reproduction Fertility and Development

Ana Paula Ferreira de Lima, Cláudio Roberto Stacheira, Francisco Ramos de Melo, Marcelo Duarte Porto, Pedro Vinícius Barreto Souza, Sônia Bessa da Costa Nicacio Silva,
Esse estudo tem como objetivo promover um diálogo e uma análise referente à educação infantil: a influência da educação 4.0 e consequências de grandes exposições para as crianças de 4 e 5 anos. Esta investigação é produto de pesquisa bibliográfica, exploratória e fundamenta-se em averiguar como a escola tem utilizado as mídias digitais para desenvolver as habilidades cognitivas das crianças, quais as contribuições pedagógicas destas tecnologias na Educação Infantil e principalmente, destacar as ...
Tópico(s): Education during COVID-19 pandemic
2023 - | Peer Review

Antônio Teixeira do Amaral Júnior, Rodrigo Moreira Ribeiro, Adriano dos Santos, Yure Pequeno de Souza, Samuel Henrique Kamphorst, Valter Jário de Lima, Flávia Nicácio Viana, Shahid Khan, Divino Rosa dos Santos, Talles de Oliveira Santos, Rosimeire Barboza Bispo, Marta Simone Mendonça Freitas, Cosme Damião Cruz, Marcelo Vivas,
The hybrids UENF N01, N02 and N03 have enhanced nitrogen-use efficiency, particularly in terms of N responsiveness, which makes them ideal for low-input cultivation. Even under abiotic stress, popping expansion is not reduced, indicating these hybrids for growth in the N and NW of Rio de Janeiro State.
Tópico(s): Crop Yield and Soil Fertility
2023 - Brazilian Society of Plant Breeding | Crop Breeding and Applied Biotechnology

Jandir Mendonça Nicácio, Leonardo Fernandes e Santana, Mateus de Sousa Rodrigues, Manoel Pereira Guimarães, Orlando Vieira Gomes, Stênio Galvão de Freitas, Sindara Nunes Parente, Marcelo Marques de Souza Lima,
A antitrombina é um anticoagulante endógeno responsável por inibir uma série de enzimas envolvidas na cascata de coagulação. Sua deficiência é rara, foi descrita pela primeira vez em 1965, tem caráter autossômico dominante, e está associada à trombose familiar. Este estudo trata-se de uma revisão narrativa de literatura realizada nas bases de dados do PubMed Central (PMC), da MEDLINE e da COCHRANE. Ao todo, 12 artigos foram elegíveis em nossa pesquisa. A análise das publicações indica que a antitrombina ...
Tópico(s): Pregnancy and preeclampsia studies
2021 - | Revista de Ensino Ciência e Inovação em Saúde

Divino Rosa dos Santos, Rodrigo Moreira Ribeiro, Antônio Teixeira do Amaral Júnior, Marcelo Vivas, Julio Cesar Gadice Saluce, Jhean Torres Leite, Rosimeire Barboza Bispo, Valter Jário de Lima, Danielle Leal Lamêgo, Kevelin Barbosa Xavier, Kátia Fabiane Medeiros Schmitt, Samuel Henrique Kamphorst, Flávia Nicácio Viana, Alexandre Pio Viana, Messias Gongaza Pereira,
Popcorn cultivation has been growing in and has positively affected the Brazilian economy. However, these crops are grown with genotypes susceptible to diseases, generating high losses. Thus, studies aimed at obtaining resistant genotypes are particularly interesting, as popcorn is susceptible to several pathogens. The most efficient, environmentally correct, and economical method of disease control is using resistant cultivars. The present study aimed to evaluate the performance of inbred lines ...
Tópico(s): Genetically Modified Organisms Research
2022 - Multidisciplinary Digital Publishing Institute | Agronomy

Álvaro Renan Vieira Nunes, Eder Ferreira Arriel, Marcelo Soares Pimentel, Maria José de Holanda Leite, Samara Paulo dos Santos Fernandes, Erik Alves Bakke, Mellina Nicácio da Luz, Leonardo Castro Arriel,
Azadirachta indica A. Juss. of the Meliácea family originates from India. It is considered important in Brazil due to its multiple uses. The plant is usually propagated by sexual reproduction (seeds), however, after harvest the seeds have to be sown as soon as possible because they lose germination viability very quickly. The use of juvenile propagules for A. indica seedlings propagation is a viable option, since there is a high demand in the semi arid regions due to wide use in urban afforestation. ...
Tópico(s): Seed Germination and Physiology
2020 - Sciencedomain International | Journal of Experimental Agriculture International
Marcelo R. de Amorim, Camila de Souza Barbosa, Tiago Antunes Paz, Laura P. Ióca, Karen de Jesus Nicácio, Lucianne Ferreira Paes de Oliveira, Mirian Oliveira Goulart, Julia M. Paulino, Mateus Oliveira da Cruz, Antônio G. Ferreira, Maysa Furlan, Simone Possedente de Lira, Raquel Alves dos Santos, André Rodrigues, Rafael V. C. Guido, Roberto G. S. Berlinck,
ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Polyketide- and Terpenoid-Derived Metabolites Produced by a Marine-Derived Fungus, Peroneutypa sp."Marcelo R. de Amorim*Marcelo R. de AmorimMore by Marcelo R. de Amorim, Camila de S. BarbosaCamila de S. BarbosaMore by Camila de S. Barbosa, Tiago A. PazTiago A. PazMore by Tiago A. Paz, Laura P. IócaLaura P. IócaMore by Laura P. Ióca, Karen J. NicácioKaren J. NicácioMore by Karen J. Nicáciohttps:// ...
Tópico(s): Fungal Biology and Applications
2023 - American Chemical Society | Journal of Natural Products

Mirella P.S. Vieira, Ozileudiane B. S. Silva, Gabriela F. Souza, Gabriela T. S. Cavalcante, Fernanda Maria Araújo de Souza, Daniel Leite Góes Gitaí, Olagide Wagner de Castro, Dannyele Cynthia Santos Pimentel Nicácio, Axel Helmut Rulf Cofré, Mariana A. Amorós, Artur V. Silva, Geraldo José da Silva Neto, Allysson H. Q. Silva, Walleska B. Z. G. B. Correia, J. Junkes, Filipe Silveira Duarte, Jéssica S. Guedes, Fábio César Sousa Nogueira, Mário R. Meneghetti, Marcelo Duzzioni,
A significant fraction of patients are affected by persistent fear and anxiety. Currently, there are several anxiolytic drug options, however their clinical outcomes do not fully manage the symptoms. Here, we evaluated the effects of a bromazepam‑palladium derivative [2-{(7-bromo-2-oxo-1,3-dihydro-2H-1,4-benzodiazepin-5-il)pyridinyl-κ2-N,N}chloropalladium(II)], [(BMZ)PdCl2], on fear/anxiety and memory-related behavior in mice. For this, female Swiss mice were treated intraperitoneally (i.p.) with saline ( ...
Tópico(s): Coordination Chemistry and Organometallics
2022 - Elsevier BV | Journal of Inorganic Biochemistry

Mirella P.S. Vieira, Ozileudiane B. S. Silva, Gabriela F. Souza, Gabriela T. S. Cavalcante, Fernanda Maria Araújo de Souza, José Renato de Oliveira e Silva Neto, Dannyele Cynthia Santos Pimentel Nicácio, Allysson H. Q. Silva, Artur V. Silva, Axel Helmut Rulf Cofré, Mariana A. Amorós, Walleska B. Z. G. B. Correia, Daniel Leite Góes Gitaí, Olagide Wagner de Castro, J. Junkes, Filipe Silveira Duarte, Jéssica S. Guedes, Fábio César Sousa Nogueira, Mário R. Meneghetti, Marcelo Duzzioni,
A significant fraction of patients is affected by persistent fear and anxiety. There are currently several anxiolytic drug options, although the clinical outcome of these existing drugs is not able to completely control symptoms. Here, we evaluated the effects of a bromazepam-palladium derivative [2-{(7-bromo-2-oxo-1,3-dihydro-2H-1,4-benzodiazepin-5-il)pyridinyl-κ2-N,N}chloropalladium(II)], [(BMZ)PdCl2 ], on fear, anxiety and memory-related behaviors in mice. For this, female Swiss mice were treated intraperitoneally ( ...
Tópico(s): Pharmacological Receptor Mechanisms and Effects
2022 - RELX Group (Netherlands) | SSRN Electronic Journal