Remedios González-Luque, Marco Garavelli, Fernando Bernardi, Manuela Merchán, Michael A. Robb, Massimo Olivucci,
In this paper we use ab initio multiconfigurational second-order perturbation theory to establish the intrinsic photoisomerization path model of retinal chromophores. This is accomplished by computing the ground state (S(0)) and the first two singlet excited-state (S(1), S(2)) energies along the rigorously determined photoisomerization coordinate of the rhodopsin chromophore model 4-cis-gamma-methylnona-2,4,6,8-tetraeniminium cation and the bacteriorhodopsin chromophore model all-trans-hepta-2,4, ...
Tópico(s): Photosynthetic Processes and Mechanisms
2000 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Antoni Salvà, Marta Roqué i Figuls, Xavier Rojano i Luque, Marco Inzitari, Sandrine Andrieu, Eduardo J. Schiffrin, Y. Guigoz, Bruno Vellas,
To estimate the number of fallers and risk factors for falls in a cohort with dementia, we did a secondary analysis of a cluster-randomized controlled trial (NutriAlz) in 11 outpatient and day care centers in Catalonia (Spain) including 626 community-dwelling patients with dementia, followed for 12 months. Participants' characteristics were assessed at baseline, at 6 and 12 months [fall in the earlier 6 mo, anthropometric data, comorbidities, Mini-Mental State Examination, Clinical Dementia Rating, ...
Tópico(s): Stroke Rehabilitation and Recovery
2011 - Lippincott Williams & Wilkins | Alzheimer Disease & Associated Disorders
Notch signaling is involved in cell differentiation and patterning, as well as in the regulation of growth and cell survival. Notch activation at the dorsal-ventral boundary of the Drosophila eye-head primordium leads to the expression of the secreted protein Unpaired, a ligand of the JAK-STAT pathway that induces cell proliferation in the undifferentiated tissue. The zinc finger proteins encoded by elbow and no ocelli are expressed in the highly proliferative region of the eye-head primordium. ...
Tópico(s): Hippo pathway signaling and YAP/TAZ
2006 - Elsevier BV | Developmental Biology
Anna Vihola, H. Luque, Marco Savarese, S. Penttilä, Mikaela Lindfors, France Leturcq, B. Eymard, Giorgio Tasca, Bernard Brais, Talita C. Conte, Karine Charton, Isabelle Richard, Bjarne Udd,
Previously, detection of ANO5 protein has been complicated by unspecific antibodies, most of which have not identified the correct protein. The aims of the study were to specify ANO5 protein expression in human skeletal muscle, and to investigate if the ANO5 protein levels are affected by different ANO5 mutations in anoctaminopathy patients.Four different antibodies were tested for ANO5 specificity. A sample preparation method compatible with membrane proteins, combined with tissue fractionation ...
Tópico(s): Cardiovascular Effects of Exercise
2017 - Wiley | Neuropathology and Applied Neurobiology
Weiyi Ouyang, Mario J. Muñoz‐Batista, Anna Kubacka, Rafael Luque, Marcos Fernández-Garcı́a,
A series of ruthenium catalysts supported into pure anatase titania were tested in the photo-production of hydrogen from methanol:water mixtures under UV and visible illumination conditions. Catalysts containing 1, 2, 3 and 5 wt.% of ruthenium were subjected to a characterization study with the help of X-ray diffraction, Raman, X-ray photoelectron spectroscopy, photoluminescence, morphology as well as scanning and transmission electron microscopy. Through the measurement of the optical properties ...
Tópico(s): TiO2 Photocatalysis and Solar Cells
2018 - Elsevier BV | Applied Catalysis B Environment and Energy
Mario J. Muñoz‐Batista, Daily Rodríguez‐Padrón, Alain R. Puente Santiago, Anna Kubacka, Rafael Luque, Marcos Fernández-Garcı́a,
Abstract Simple modifications of g‐C 3 N 4 (CN) have been studied to maximize hydrogen production under sunlight irradiation conditions. The relatively low surface area CN obtained was subjected to an exfoliation process which 1) increases available catalytic area and 2) modulates the semiconductor charge photohandling. MnO x and metallic Pt, which can act as co‐catalysts, were subsequently added on the surface of exfoliated or bulk counterparts, producing an active material suitable for sunlight ...
Tópico(s): TiO2 Photocatalysis and Solar Cells
2018 - Wiley | ChemPhotoChem
Laura Remacha, David Pirman, Christopher E. Mahoney, Javier Pardo de Santayana y Coloma, Bruna Calsina, María Currás-Freixes, Rocío Letón, Rafael Torres‐Pérez, Susan Richter, Guillermo Pita, Belén Herráez, Giovanni Cianchetta, Emiliano Honrado, Lorena Maestre, Miguel Urioste, Javier Aller, Óscar García-Uriarte, María A. Gálvez, Raúl M. Luque, Marcos Lahera, Cristina Moreno-Rengel, Graeme Eisenhofer, Cristina Montero‐Conde, Cristina Rodríguez‐Antona, Óscar Llorca, Gromoslaw A. Smolen, Mercedes Robledo, Alberto Cascón,
(The American Journal of Human Genetics 104, 651–664; April 4, 2019) In the original article, Figure 3 was mislabeled. In panels C and D, the substitution p.Gly374Glu was incorrectly labeled as p.Gly374Arg in the bar graphs. The article has now been corrected online. The authors regret this error and apologize for any confusion that may have resulted.Figure 3. Functional Analysis of DLST Variants (Original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) Recurrent Germline DLST Mutations ...
Tópico(s): Cancer, Lipids, and Metabolism
2019 - Elsevier BV | The American Journal of Human Genetics
Laura Remacha, David Pirman, Christopher E. Mahoney, Javier Pardo de Santayana y Coloma, Bruna Calsina, María Currás-Freixes, Rocío Letón, Rafael Torres‐Pérez, Susan Richter, Guillermo Pita, Belén Herráez, Giovanni Cianchetta, Emiliano Honrado, Lorena Maestre, Miguel Urioste, Javier Aller, Óscar García-Uriarte, María A. Gálvez, Raúl M. Luque, Marcos Lahera, Cristina Moreno-Rengel, Graeme Eisenhofer, Cristina Montero‐Conde, Cristina Rodríguez‐Antona, Óscar Llorca, Gromoslaw A. Smolen, Mercedes Robledo, Alberto Cascón,
Pheochromocytomas and paragangliomas (PPGLs) provide some of the clearest genetic evidence for the critical role of metabolism in the tumorigenesis process. Approximately 40% of PPGLs are caused by driver germline mutations in 16 known susceptibility genes, and approximately half of these genes encode members of the tricarboxylic acid (TCA) cycle. Taking as a starting point the involvement of the TCA cycle in PPGL development, we aimed to identify unreported mutations that occurred in genes involved ...
Tópico(s): Glioma Diagnosis and Treatment
2019 - Elsevier BV | The American Journal of Human Genetics
Uriel Caudillo‐Flores, Mario J. Muñoz‐Batista, Rafael Luque, Marcos Fernández-Garcı́a, Anna Kubacka,
Tópico(s): Perovskite Materials and Applications
2019 - Elsevier BV | Chemical Engineering Journal
Uriel Caudillo‐Flores, Daily Rodríguez‐Padrón, Mario J. Muñoz‐Batista, Anna Kubacka, Rafael Luque, Marcos Fernández-Garcı́a,
Metal boron–g-C 3 N 4 composite samples synthesized by mechanochemisty with remarkable selectivity to acetone during the photo-oxidation of 2-propanol.
Tópico(s): Perovskite Materials and Applications
2020 - Royal Society of Chemistry | Green Chemistry
Gianluca Pellino, Rafael Alós, Sebastiano Biondo, Antonio Codina Cazador, José M. Enríquez–Navascués, Eloy Espín, José Vicente Roig‐Vila, Andrés Cervantes, Eduardo García‐Granero, R Adell Carceller, Juan Guillermo Ais Conde, Evelio Alonso Alonso, Antonio Amaya Cortijo, Antonio Arroyo Sebastián, Pedro Barra Baños, Ricard Batlle Solé, Juan Carlos Bernal Sprekelsen, Sebastiano Biondo, Francisco Javier Blanco González, S Vázquez Blanco, Jesús Bollo, Nieves Cáceres Alvarado, Ignasi Camps Ausàs, Ramón Cantero Cid, José Antonio Carmona Saez, Enrique Núñez, Luis-Cristóbal Capitán-Morales, Guillermo Carreño Villarreal, Jesús Cifuentes Tébar, Miguel A. Lozano, Antonio Codina Cazador, Juan de Dios Franco Osorio, María de la Vega Olías, Mario de Miguel Velasco, Sergio Rodrigo del Valle, José G. Díaz Mejías, J. M. Díaz Pavón, Javier Díe Trill, J.L. Domínguez Tristancho, Paula Dujovne Lindenbaum, José Errasti Alustiza, Alejandro Espí Macías, Eloy Espín, Rafael Estevan, Alfredo M. Estevez Diz, Luis Flores-Padilla, Doménico Fraccalvieri, Alessandro Garcea, Mauricio García Alonso, M. Botella, Maria José García Coret, Alfonso García Fadrique, José-María García-García, J. García García, Eduardo García‐Granero, Jesus Alvarez, José Gomez Barbadillo, Fernando Gris, Verónica Gumbau, Javier Gutierrez, Pilar Hernández Casanovas, Daniel Huerga Álvarez, Ana M. Huidobro Piriz, Francisco Javier Jiménez Miramón, Ana Lage Laredo, Alberto Lamiquiz Vallejo, Félix Lluís Casajuana, Manuel López Lara, Juan Mompeán, María Victoría Maestre, Eva Martí Martínez, M. Martinez, Javier Martínez Alegre, Gabriel Martínez Gallego, Roberto Martinez Pardavila, Olga Maseda Díaz, Mónica Millan Schedling, Benito Mirón, Jose M. Abad, José A. Múgica Martinera, Francisco Olivet Pujol, Mónica Orelogio Orozco, Luis Ortiz de Zárate, Rosana Palasí Gimenez, Natividad Palencia García, P. Palma, Alberto Parajó Calvo, Jesús Paredes Cotoré, Carlos Pastor Idoate, Miguel Pera Román, Francisco Pérez Benítez, José A. Pérez García, Marta Piñol Pascual, I. Nieto, Ricardo Rada Morgades, Mónica Reig Pérez, Ángel Reina Duarte, Didac Ribé Serrat, Xavier Rodamilans, María Dolores Carmona-Luque, Marcos Rodriguez Martin, Francisco Romero Aceituno, Jesús Salas Martínez, Ginés Sánchez de la Villa, Inmaculada Segura Jiménez, José Enrique Sierra Grañón, Amparo Solana Bueno, Albert Sueiras Gil, Teresa Torres‐Sánchez, Natalia Uribe Quintana, Javier Valdés-Hernández, Fancesc Vallribera, V. Viciano Pascual,
Preoperative treatment and adequate surgery increase local control in rectal cancer. However, modalities and indications for neoadjuvant treatment may be controversial. Aim of this study was to assess the trends of preoperative treatment and outcomes in patients with rectal cancer included in the Rectal Cancer Registry of the Spanish Associations of Surgeons.This is a STROBE-compliant retrospective analysis of a prospective database. All patients operated on with curative intention included in the ...
Tópico(s): Colorectal Cancer Screening and Detection
2020 - Elsevier BV | European Journal of Surgical Oncology
Esteban J. Palomo, Enrique Domínguez, Rafael Marcos Luque‐Baena, J.T. Entrambasaguas,
The self-organizing map (SOM) have shown to be successful for the analysis of high-dimensional input data as in data mining applications such as network security. However, the static architecture and the lack of representation of hierarchical relations are its main drawbacks. The growing hierarchical SOM (GHSOM) address these limitations of the SOM. The GHSOM is an artificial neural network model with hierarchical architecture composed of independent growing SOMs. One limitation of these neural networks ...
Tópico(s): Network Packet Processing and Optimization
2008 - Springer Science+Business Media | Lecture notes in computer science
Rafael Marcos Luque‐Baena, Enrique Domínguez, Esteban J. Palomo, J.T. Entrambasaguas,
This paper presents a neural background modeling based on subtraction approach for video object segmentation. A competitive neural network is proposed to form a background model for traffic surveillance. The unsupervised neural classifier handles the segmentation in natural traffic sequences with changes in illumination. The segmentation performance of the proposed neural network is qualitatively examined and compared to mixture of Gaussian models. The proposed algorithm is designed to enable efficient ...
Tópico(s): Advanced Vision and Imaging
2008 - Springer Science+Business Media | Lecture notes in computer science
Ezequiel López‐Rubio, Rafael Marcos Luque‐Baena, Enrique Domínguez,
Background modeling and foreground detection are key parts of any computer vision system. These problems have been addressed in literature with several probabilistic approaches based on mixture models. Here we propose a new kind of probabilistic background models which is based on probabilistic self-organising maps. This way, the background pixels are modeled with more flexibility. On the other hand, a statistical correlation measure is used to test the similarity among nearby pixels, so as to enhance ...
Tópico(s): Advanced Image and Video Retrieval Techniques
2011 - World Scientific | International Journal of Neural Systems
Ezequiel López‐Rubio, Rafael Marcos Luque‐Baena,
Many background modelling approaches are based on mixtures of multivariate Gaussians with diagonal covariance matrices. This often yields good results, but complex backgrounds are not adequately captured, and post-processing techniques are needed. Here we propose the use of mixtures of uniform distributions and multivariate Gaussians with full covariance matrices. These mixtures are able to cope with both dynamic backgrounds and complex patterns of foreground objects. A learning algorithm is derived ...
Tópico(s): Human Pose and Action Recognition
2011 - Elsevier BV | Computer Vision and Image Understanding
Rafael Marcos Luque‐Baena, Juan Miguel Ortiz-de-Lazcano-Lobato, Ezequiel López‐Rubio, Enrique Domínguez, Esteban J. Palomo,
Tópico(s): Human Pose and Action Recognition
2012 - Springer Science+Business Media | Neural Processing Letters
Rafael Marcos Luque‐Baena, David Elizondo, Ezequiel López‐Rubio, Esteban J. Palomo, Tim Watson,
This paper studies the reliability of geometric features for the identification of users based on hand biometrics. Our methodology is based on genetic algorithms and mutual information. The aim is to provide a system for user identification rather than a classification. Additionally, a robust hand segmentation method to extract the hand silhouette and a set of geometric features in hard and complex environments is described. This paper focuses on studying how important and discriminating the hand ...
Tópico(s): Hand Gesture Recognition Systems
2012 - Elsevier BV | Expert Systems with Applications
Esteban J. Palomo, Janet M. Wilmshurst, David Elizondo, Rafael Marcos Luque‐Baena, Tim Watson,
Digital investigation methods are becoming more and more important due to the proliferation of digital crimes and crimes involving digital evidence. Network forensics is a research area that gathers evidence by collecting and analysing network traffic data logs. This analysis can be a difficult process, especially because of the high variability of these attacks and large amount of data. Therefore, software tools that can help with these digital investigations are in great demand. In this paper, ...
Tópico(s): Data Visualization and Analytics
2012 - Elsevier BV | Neural Networks
Rafael Marcos Luque‐Baena, Daniel Urda, M. Gonzalo Claros, Leonardo Franco, José M. Jerez,
Genetic algorithms are widely used in the estimation of expression profiles from microarrays data. However, these techniques are unable to produce stable and robust solutions suitable to use in clinical and biomedical studies. This paper presents a novel two-stage evolutionary strategy for gene feature selection combining the genetic algorithm with biological information extracted from the KEGG database. A comparative study is carried out over public data from three different types of cancer (leukemia, ...
Tópico(s): Machine Learning in Bioinformatics
2014 - Elsevier BV | Journal of Biomedical Informatics
Víctor Rosenthal, Dennis G. Maki, Yatin Mehta, Hakan Leblebicioğlu, Ziad A. Memish, Haifaa H. Al-Mousa, Hanan H. Balkhy, Bijie Hu, Carlos Álvarez, Eduardo Alexandrino Medeiros, Anucha Apisarnthanarak, Lul Raka, Luis E. Cuéllar, Altaf Ahmed, Josephine Anne Navoa-Ng, Amani El‐Kholy, Souha S. Kanj, Ider Bat-Erdene, Wiesława Duszyńska, Nguyễn Văn Trường, Leonardo N. Pazmino, Lucy Chai See-Lum, Rosalía Fernández-Hidalgo, Gabriela Di-Silvestre, Farid Zand, Soňa Hlinková, Vladislav Belskiy, Hussain Al-Rahma, Marco Tulio Luque-Torres, Nesil Bayraktar, Zan Mitrev, Vaidotas Gurskis, Dale Fisher, Ilham B. Abu-Khader, Kamal Berechid, Arnaldo Rodríguez-Sánchez, Florin George Horhat, Osiel Requejo-Pino, N Hadjieva, Nejla Ben-Jaballah, Elías García-Mayorca, Luis Kushner-Dávalos, Srdjan Pasic, Luis E. Pedrozo-Ortiz, Eleni Apostolopoulou, Nepomuceno Mejía, May Osman Gamar-Elanbya, Kushlani Jayatilleke, Miriam de Lourdes-Dueñas, Guadalupe Aguirre-Ávalos, Diego Maurizi, Adriana Montanini, María Laura Spadaro, Lorenzo Santiago Marcos, Priscila Botta, Florencia Maria Jerez, Maria Chávez, Lucia Ramasco, Maria Isabel Colqui, Maria Silvia Olivieri, Ana Silvia Rearte, Gladys Edith Correa, P. Juárez, Paola Fabiana Gallardo, Miriam Patricia Brito, Gabriel Horacio Mendez, Julia Rosa Valdez, Lorena Paola Cardena, Jose Maria Harystoy, Gustavo Chaparro, Claudia Gabriela Rodriguez, Rodolfo Toomey, Maria de los Ángeles Caridi, Mônica Pereira Campanha Viegas, Marisa L Bernan, Adriana Romaní, Claudia Beatriz Dominguez, Luis Kushner Davalos, Rosana Richtmann, Camila Almeida Silva, Tatiane Rodrigues, Amaury Mielle Filho, Ernandi Dagoberto Seerig Palme, Aline Besen, Caroline Lazzarini, Caroline Batista Cardoso, Francisco Kennedy Scofoni Faleiros de Azevedo, Ana Paula Pinheiro, Aparecida Camacho, Bráulio Matias de Carvalho, Maria Jose Monteiro De Assis, Ana Paula Vasconcelos Carneiro, Maria Lilian Maciel Canuto, Keyla Harten Pinto Coelho, T.T.S.L. Moreira, Agamenon Alves Oliveira, Marcela Maria Sousa Colares, Marcia Maria De Paula Bessa, Tereza de Jesus Pinheiro Gomes Bandeira, Renata Amaral De Moraes, Danilo Amâncio Campos, Tânia Mara Lima De Barros Araújo, Maria Tereza Freitas Tenório, Simone Cristina de Amorim, Manuela Cristina Gouveia do Amaral, Julianne Da Luz Lima, Lindalva Pino Da Silva Neta, Caphiane Batista, Fabio Jorge De Lima Silva, Maria C. Ferreira De Souza, Katia Arruda Guimaraes, Julia Marcia Maluf Lopes, Karina Martins Nogueira Napoles, Lorena Luiza Silva Neto Avelar, Lilian Aguiar Vieira, Luis Gustavo De Oliveira Cardo, Christianne Fernandes Valente Takeda, Glaydson A. Ponte, Fco Eduardo Aguiar Leitão, Ricardo de Souza Kuchenbecker, Rodrigo Pires dos Santos, Erci Maria Onzi Siliprandi, Luiz Fernando Baqueiro Freitas, Ianick Souto Martins, Daiane Casi, Maria Angela Maretti Da Silva, S Blecher, Margarete Villins, Reinaldo Salomão, Solange Regina Oliveira Castro, Daniela Vieira da Silva Escudero, Mariana Andrade Oliveira Reis, Marcelo Mendonça, Valter Furlan, Antônio Cláudio do Amaral Baruzzi, Tarquino Eristidesg Sanchez, Marina Moreira, Wania Vasconcelos de Freitas, Leonardo Passos de Souza, V. Velinova, N Hadjieva, Michael M. Petrov, Dimitar Georgiev Karadimov, Emil D. Kostadinov, Violeta Jivkova Dicheva, Chaohua Wang, Xiuqin Guo, Xihua Geng, Shufang Wang, Jinzhi Zhang, Ling Zhu, Shufang Zhuo, Chunli Guo, Lili Tao, Ruisheng Li, Kun Liu, Xuesong Yang, LI Yi-min, Pu Mao, Changan Li, Yiang Shumei, Wu Kangxiong, Lin Meiyi, Guxiang Ye, Zi-Qin Xu, Yao Suo, Song Li-qiang, Luis Marino Cañas Giraldo, Elsa Margarita Trujillo Ramirez, Paola Andrea Rios, Juan Carlos Torres Millan, Edwin Giovanny Chapeta Parada, Andres Eduardo Mindiola Rochel, Andres H. Corchuelo Martinez, Ana Marãa Perez Fernandez, Nayide Barahona-Guzmán, Alfredo Lagares Guzman, Marena Rodríguez-Ferrer, Yazmin Leon Vega, Heidi Johanna Munoz, Germán Camacho‐Moreno, Sandra Liliana Romero Torres, Herlidia Taboada Hernandez, Ismael A. Valderrama MarquezClaudia Linares, Monica Espinosa Valencia, Lusayda Sanchez Corrales, Sandra Milena Bonilla, Jorge Ivan Marin Uribe, David Yepes Gomez, Javier Martínez, Luz Dary Burgos Florez, Johanna Osorio, Dagoberto Santofimio, L Cortés, Wilmer E. Villamil‐Gómez, Gabriel Gutierrez, Adela Arguello Ruiz, Carlos Gonzalez Fuentes, Antonio Solano Chinchilla, Ivar Calvo Hernandez, Olber Chavarría Ugalde, Humberto Guanche Garcell, Clara Morales Perez, Selin Bardak, Sec inodot l Ozkan, Nepomuceno Mejía, Adrian M. Puello Guerrero Glenny Mirabal, Margarita Delgado, Ramona Severino, Eliesel Lacerda, Gilda Tolari, María Marcela Bovera, Diego Barahona Pinto, P González, Gasdali Santacruz, Nelly Alquinga, Celso Zaruma, Nelson Remache, Diego Morocho, Mario F Arboleda, M. C. Navarro Zapata, María Fernanda Garcia, Fabricio Picoita, Jorge Luis Vélez Páez, M. Valle, Estuardo Salgado Yepez, Diego Morocho Tutillo, Ricardo Mora, Andrea Peña Padilla, Mayra Chango, Karina Cabezas, Shirley Tenorio López, Ana Lucía Bonilla Escudero, Gladys Tatiana Sánchez, Hugo Alberto Gonzalez Flores, María Fernanda Garcia, Islam Abdullorziz Ghazi, Mohamed Hassan, Ghada Ismail, Reham Hamed, Mona Mohiedden Abdel-Halim, May Abd El-Fattah, Doaa M. Abdelaziz, Zeinab Salah Seliem, Rasha Elsherif, Reham Ali Dewdar, Abeer Ahmed Mohmed, Lamiaa Abdel-Fatteh Ahmed, Lilian de Jesús Machuca, Concepcion Bran De Casares, Prokopis Kithreotis, Maria Daganou, Dimitrios Veldekis, Maria Kartsonaki, Achilleas Gikas, Marco Tulio Luque Torres, Denis Padgett, Doris Maribel Rivera, Namita Jaggi, Camilla Rodrigues, Bhagyesh Shah, Keyur Parikh, Jigar Patel, Riya Thakkar, Murali Chakravarthy, B.N. Gokul, R. Sukanya, Leema Pushparaj, Thejas Vini, Sukanya Rangaswamy, Saroj Kumar Patnaik, V Venkateshwar, Biju John, Shamsher Dalal, Suneeta Sahu, Samir Sahu, Banambar Ray, Sudhiranjan Misra, Nisith Mohanty, Biraj Mohan Mishra, Prafulla Sahoo, Naresh Parmar, Sanghamitra Mishra, Basanta Kumar Pati, Santosh Kumar Singh, Bhabani Shankar Pati, Aparajita Panda, Swarna Banergee, Dipankar Padhihari, Soumya Samal, Samir Sahu, Karthikeya Varma, Velu Pandi Suresh Kumar, Ram Gopalakrishnan, Nagarajan Ramakrishnan, Babu K. Abraham,
We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC' ...
Elsevier BV
Rafael Marcos Luque‐Baena, Daniel Urda, José Luis Subirats, Leonardo Franco, José M. Jerez,
Extracting relevant information from microarray data is a very complex task due to the characteristics of the data sets, as they comprise a large number of features while few samples are generally available. In this sense, feature selection is a very important aspect of the analysis helping in the tasks of identifying relevant genes and also for maximizing predictive information. Due to its simplicity and speed, Stepwise Forward Selection (SFS) is a widely used feature selection technique. In this ...
Tópico(s): Machine Learning in Bioinformatics
2014 - Springer Science+Business Media | Theoretical Biology and Medical Modelling
Ezequiel López‐Rubio, David Elizondo, Martin Grootveld, José M. Jerez, Rafael Marcos Luque‐Baena,
The advent of the information age, also commonly known as the digital age, has made a profound impact on health sciences. Vast amounts of datasets now flow through the different stages of healthcare organizations, and there is a major requirement to extract knowledge and employ it to improve these centres in all respects. Intelligent computer systems provide support to health professionals involved both in the medical and managerial contexts. Amongst these systems, computational intelligence approaches ...
Tópico(s): Artificial Intelligence in Healthcare
2015 - Hindawi Publishing Corporation | Computational and Mathematical Methods in Medicine
Francisco Ortega-Zamorano, José M. Jerez, Daniel Urda, Rafael Marcos Luque‐Baena, Leonardo Franco,
The well-known backpropagation learning algorithm is implemented in a field-programmable gate array (FPGA) board and a microcontroller, focusing in obtaining efficient implementations in terms of a resource usage and computational speed. The algorithm was implemented in both cases using a training/validation/testing scheme in order to avoid overfitting problems. For the case of the FPGA implementation, a new neuron representation that reduces drastically the resource usage was introduced by combining ...
Tópico(s): Analog and Mixed-Signal Circuit Design
2015 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Neural Networks and Learning Systems
Francisco J. Veredas, Rafael Marcos Luque‐Baena, Francisco Javier Martín‐Santos, Juan Carlos Morilla Herrera, Laura Morente,
Tópico(s): Wound Healing and Treatments
2015 - Elsevier BV | Neurocomputing
Rafael Marcos Luque‐Baena, Ezequiel López‐Rubio, Enrique Domínguez, Esteban J. Palomo, José M. Jerez,
Tópico(s): Image Enhancement Techniques
2015 - Springer Science+Business Media | Soft Computing
Ezequiel López‐Rubio, Miguel A. Molina‐Cabello, Rafael Marcos Luque‐Baena, Enrique Domínguez,
One of the most important challenges in computer vision applications is the background modeling, especially when the background is dynamic and the input distribution might not be stationary, i.e. the distribution of the input data could change with time (e.g. changing illuminations, waving trees, water, etc.). In this work, an unsupervised learning neural network is proposed which is able to cope with progressive changes in the input distribution. It is based on a dual learning mechanism which manages ...
Tópico(s): Image Enhancement Techniques
2017 - World Scientific | International Journal of Neural Systems
Francisco J. Rodríguez, A. Macı́as-Garcı́a, Pedro J. Pardo, Francisco Chávez, Rafael Marcos Luque‐Baena,
Tópico(s): Advanced Chemical Sensor Technologies
2017 - Springer Science+Business Media | Progress in Artificial Intelligence
Michelle Giles, Amit C. Achhra, Alison G. Abraham, Andreas D. Haas, M. John Gill, Man Po Lee, Marco Luque, Catherine C. McGowan, Morna Cornell, Paula Braitstein, Nathalie de Rekeneire, Renaud Becquet, Kara Wools‐Kaloustian, Matthew Law,
Abstract Introduction In 2015, the World Health Organization recommended that all HIV ‐infected individuals consider ART initiation as soon as possible after diagnosis. Sex differences in choice of initial ART regimen, indications for switching, time to switching and choice of second‐line regimens have not been well described. The aims of this study were to describe first‐line ART and CD 4 count at ART initiation by sex, calendar year and region, and to analyse time to change or interruption in first‐ ...
Tópico(s): HIV Research and Treatment
2018 - International AIDS Society | Journal of the International AIDS Society
Miguel A. Molina‐Cabello, Rafael Marcos Luque‐Baena, Ezequiel López‐Rubio, Karl Thurnhofer‐Hemsi,
The automatic detection and classification of vehicles in traffic sequences is a typical task which is carried out in many practical video surveillance systems. The advent of deep learning has facilitated the design of these systems. However, limitat
Tópico(s): Anomaly Detection Techniques and Applications
2018 - IOS Press | Integrated Computer-Aided Engineering
Jorge García-González, Juan Miguel Ortiz-de-Lazcano-Lobato, Rafael Marcos Luque‐Baena, Miguel A. Molina‐Cabello, Ezequiel López‐Rubio,
A robust foreground detection system is presented, which is resilient to noise in video sequences. The proposed model divides each video frame in patches that are fed to a stacked denoising autoencoder, which is responsible for the extraction of significant features from each image patch. After that, a probabilistic model that is composed of a mixture of Gaussian distributions decides whether the given feature vector describes a patch belonging to the background or the foreground. In order to test ...
Tópico(s): Advanced Vision and Imaging
2019 - Elsevier BV | Pattern Recognition Letters