Marco A. Lezama-Reus, Gregorio Moreno-Penagos, Sergio G. Ram rez-Ledesma, Marco A. Lozano-Guti rrez, Francisco Ramos-Valdelamar,
Lezama-Reus, Marco A. M.D.; Moreno-Penagos, Gregorio M.D.; Ramírez-Ledesma, Sergio G. M.D.; Lozano-Gutiérrez, Marco ...
Tópico(s): Cleft Lip and Palate Research
2007 - Lippincott Williams & Wilkins | Plastic & Reconstructive Surgery
Denisa Bojková, Rui Costa, Philipp Reus, Marco Bechtel, Mark-Christian Jaboreck, Ruth Olmer, Ulrich Martin, Sandra Ciesek, Martin Michaelis, Jindřich Činátl,
SARS-CoV-2 is causing the coronavirus disease 2019 (COVID-19) pandemic, for which effective pharmacological therapies are needed. SARS-CoV-2 induces a shift of the host cell metabolism towards glycolysis, and the glycolysis inhibitor 2-deoxy-d-glucose (2DG), which interferes with SARS-CoV-2 infection, is under development for the treatment of COVID-19 patients. The glycolytic pathway generates intermediates that supply the non-oxidative branch of the pentose phosphate pathway (PPP). In this study, ...
Tópico(s): Diabetes and associated disorders
2021 - Multidisciplinary Digital Publishing Institute | Metabolites
Produção Nacional
Gislaine Z. Réus, Marcos Nacif, Helena M. Abelaira, Débora B. Tomaz, M.A. Santos, Anelise S. Carlessi, Beatriz I. Matias, Jaine da Luz, Amanda V. Steckert, Gabriela C. Jeremias, Giselli Scaini, Meline Oliveira dos Santos Morais, Emílio L. Streck, João Quevedo,
Studies have suggested that ketamine, a nonselective NMDA receptor antagonist, could be a new drug in the treatment of major depression, but the way ketamine presents such effects remains to be elucidated. Therefore, the objective of this paper was to evaluate the effects of ketamine treatment on parameters related to depression in the brain of adult rats subjected to an animal model of depression. The animals were divided into: non-deprived + saline; non-deprived + ketamine; deprived + saline; deprived + ...
Tópico(s): Anesthesia and Neurotoxicity Research
2015 - Bentham Science Publishers | Current Neurovascular Research
Produção Nacional
Revisado por pares
Gislaine Z. Réus, Marcos Nacif, Helena M. Abelaira, Débora B. Tomaz, Maria Augusta B. dos Santos, Anelise S. Carlessi, Jaine R. da Luz, Renata Casagrande Gonçalves, Francieli Vuolo, Felipe Dal‐Pizzol, André F. Carvalho, João Quevedo,
A growing body of evidence points toward an association between the glutamatergic system, as well as immune system dysregulation and major depression. So, the present study was aimed at evaluating the behavioral and molecular effects of the ketamine, an antagonist of the N-methyl-d-aspartate (NMDA) receptor of glutamate in maternally deprived adult rats. In deprived rats treated with saline, we observed an increase in the immobility time; however, ketamine treatment reversed this effect, decreasing ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2014 - Elsevier BV | Neuroscience Letters
Ronald Tilson, Peter Maurice Norton,
... org/10.1016/j.yhbeh.2021.105062Koen de Reus, Masayo Soma, Marianna Anichini, Marco Gamba, Marianne de Heer Kloots, Miriam Lense, Julia ...
Tópico(s): Animal Behavior and Reproduction
1981 - University of Chicago Press | The American Naturalist
Denisa Bojková, Philipp Reus, Leona Panosch, Marco Bechtel, Tamara Rothenburger, Joshua D. Kandler, Annika Pfeiffer, Julian U. G. Wagner, Mariana Shumliakivska, Stefanie Dimmeler, Ruth Olmer, Ulrich Martin, Florian W. R. Vondran, Tuna Toptan, Florian Rothweiler, Richard Zehner, Holger F. Rabenau, Karen L. Osman, Steven T. Pullan, Miles W. Carroll, Richard S. Stack, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindřich Činátl,
Reliable, easy-to-handle phenotypic screening platforms are needed for the identification of anti-SARS-CoV-2 compounds. Here, we present caspase 3/7 activity as a readout for monitoring the replication of SARS-CoV-2 isolates from different variants, including a remdesivir-resistant strain, and of other coronaviruses in numerous cell culture models, independently of cytopathogenic effect formation. Compared to other models, the Caco-2 subline Caco-2-F03 displayed superior performance. It possesses ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2023 - Cell Press | iScience
Koen de Reus, Masayo Soma, Marianna Anichini, Marco Gamba, Marianne de Heer Kloots, Miriam D. Lense, Julia Hyland Bruno, Laurel J. Trainor, Andrea Ravignani,
This review paper discusses rhythmic interactions and distinguishes them from non-rhythmic interactions. We report on communicative behaviours in social and sexual contexts, as found in dyads of humans, non-human primates, non-primate mammals, birds, anurans and insects. We discuss observed instances of rhythm in dyadic interactions, identify knowledge gaps and propose suggestions for future research. We find that most studies on rhythmicity in interactive signals mainly focus on one modality (acoustic ...
Tópico(s): Animal Behavior and Reproduction
2021 - Royal Society | Philosophical Transactions of the Royal Society B Biological Sciences
Guusje Collin, Martijn P. van den Heuvel, Lucija Abramovic, Annabel Vreeker, Marcel A. de Reus, Neeltje E.M. van Haren, Marco P. Boks, Roel A. Ophoff, René S. Kahn,
The notion that healthy brain function emerges from coordinated neural activity constrained by the brain's network of anatomical connections--i.e., the connectome--suggests that alterations in the connectome's wiring pattern may underlie brain disorders. Corroborating this hypothesis, studies in schizophrenia are indicative of altered connectome architecture including reduced communication efficiency, disruptions of central brain hubs, and affected "rich club" organization. Whether similar deficits ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2015 - Wiley | Human Brain Mapping
Íñigo López-Azkarreta, Sergio Reus, Pascual Marco, José Sánchez‐Payá, José Murcia, María Isabel Manso, Miguel Pérez‐Mateo,
The incidence and risk factors for the development of post-thrombotic syndrome (PTS) are not well known, so the aim of our study is to evaluate the development of PTS after proximal deep vein thrombosis (DVT) and its relationship with several clinical, laboratory and therapeutic factors.Prospective, observational study.consecutive patients with acute symptomatic proximal DVT in the lower extremities diagnosed between February 2000 and July 2002.life expectancy < 12 months, impossibility for follow-up, ...
Tópico(s): Central Venous Catheters and Hemodialysis
2005 - Elsevier BV | Medicina Clínica
María José Díez, Asunción Díaz, César Garriga, Matias Reus-Pons, Ana Sales Ten, Henar Marcos, Félix Gutiérrez, Santiago Moreno, Juan González‐García, Ana Barrios, Sari Arponen, M T García, María Carmen García Royo, J. Toledo, G González, Rosa Aranguren, Ana Izquierdo, Luis Viloria, L. Elizalde, Eva Martínez, Daniel Castrillejo, Irene López, C. López Redondo, Ariel Cano, collective the Hospital Survey Study Group,
A second-generation surveillance system of people infected with human immunodeficiency virus (HIV) has been implemented in Spain. Behavioural and clinical data were collected between 2002 and 2011 through an annual one-day, cross-sectional survey in public hospitals, including all in- and outpatients receiving HIVrelated care on the survey day. Mean age increased over time (from 38.7 years in 2002 to 43.8 years in 2011) and 68.4% of the 7,205 subjects were male. The proportion of migrants increased ...
Tópico(s): Sex work and related issues
2014 - European Centre for Disease Prevention and Control | Eurosurveillance
Isabela Porto de Toledo, Jéssica Conti Réus, Mariana Fernandes, André Luís Porporatti, Marco Aurélio Peres, Augusto Key Karazawa Takaschima, Marcelo Neves Linhares, Eliete Neves Silva Guerra, Graziela De Luca Canto,
Background The aim of this systematic review was to answer the focused question, “What are the prevalence and the epidemiological characteristics of trigeminal neuralgia in the general population?” Types of Studies Reviewed This systematic review included observational population-based studies reporting the prevalence of trigeminal neuralgia (TN). The authors developed specific search strategies for LILACS, PubMed, ScienceDirect, Scopus, Web of Science, and Google Scholar. The authors evaluated the ...
Tópico(s): Oropharyngeal Anatomy and Pathologies
2016 - Elsevier BV | The Journal of the American Dental Association
Produção Nacional
Revisado por pares
Lígia Figueiredo Valesan, Cecília Doebber Da-Cas, Jéssica Conti Réus, Ana Cristina Scremin Denardin, Roberto Ramos Garanhani, Daniel Marcos Bonotto, Eduardo Januzzi, Beatriz Dulcinéia Mendes de Souza,
Tópico(s): Orthodontics and Dentofacial Orthopedics
2021 - Springer Nature | Clinical Oral Investigations
Katie-May McLaughlin, Denisa Bojková, Joshua D. Kandler, Marco Bechtel, Philipp Reus, Trang T. Le, Florian Rothweiler, Julian U. G. Wagner, Andreas Weigert, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindřich Činátl,
The coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Most SARS-CoV-2 infections are mild or even asymptomatic. However, a small fraction of infected individuals develops severe, life-threatening disease, which is caused by an uncontrolled immune response resulting in hyperinflammation. However, the factors predisposing individuals to severe disease remain poorly understood. Here, we show that levels of CD47, which is known to mediate immune escape in cancer and virus-infected ...
Tópico(s): Phagocytosis and Immune Regulation
2021 - Caister Academic Press | Current Issues in Molecular Biology
Produção Nacional
Revisado por pares
E. Casett, Jéssica Conti Réus, Juliana Stuginski‐Barbosa, André Luís Porporatti, Maria Clotilde Carra, Marco Aurélio Peres, Graziela De Luca Canto, Daniele Manfredini,
Summary This systematic review and meta‐analysis ( MA ) aimed to evaluate the diagnostic validity of questionnaires, clinical assessment and portable diagnostic devices compared to the reference standard method polysomnography ( PSG ) in assessing sleep bruxism ( SB ). Two reviewers searched electronic databases for diagnostic test accuracy studies that compared questionnaires, clinical assessment or portable diagnostic devices for SB , with the reference standard method PSG , comprising previous studies from all ...
Tópico(s): Voice and Speech Disorders
2017 - Wiley | Journal of Oral Rehabilitation
Christian Reus, Marc P. Lechner, Matthias B. Schulze, Dominik Lungerich, Colin Diner, Marco Gruber, Jeffrey M. Stryker, Frank Hampel, Norbert Jux, Rik R. Tykwinski,
The synthesis and properties of a new polycyclic aromatic hydrocarbon containing eight annulated rings and based on the anthanthrene core is described. An unexpected, nucleophile-dependent Michael addition to a dibenzanthanthrene-1,7-dione is found, giving a product with three triisopropylsilylacetylene units and a remarkable solid-state structure (as determined by X-ray crystallography).
Tópico(s): Porphyrin and Phthalocyanine Chemistry
2016 - Wiley | Chemistry - A European Journal
Produção Nacional
Revisado por pares
Thamile Luciane Reus, Anny Waloski Robert, Marise Brenner Affonso da Costa, Alessandra Melo de Aguiar, Marco Augusto Stimamiglio,
In the heart, tissue-derived signals play a central role on recruiting/activating stem cell sources to induce cardiac lineage specification for maintenance of tissue homeostasis and repair. Cardiac resident stromal cells (CRSCs) may play a pivotal role in cardiac repair throughout their secretome. Here, we performed the characterization of CRSCs and their secretome by analyzing the composition of their culture-derived extracellular matrix (ECM) and conditioned medium (CM) and by investigating their ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2016 - Elsevier BV | International Journal of Cardiology
Produção Nacional
Revisado por pares
Renan P. Souza, Eliane Cristina de Souza Soares, Daniela Rosa, Bruno Rezende Souza, Gislaine Z. Réus, Tatiana Barichello, Karin Martins Gomes, Marcus V. Gomez, João Quevedo, Marco Aurélio Romano‐Silva,
Methylphenidate has been used as an effective treatment for attention deficit hyperactivity disorder (ADHD). Methylphenidate (MPH) blocks dopamine and norepinephrine transporters causing an increase in extracellular levels. The use of psychomotor stimulants continues to rise due to both the treatment of ADHD and illicit abuse. Methylphenidate sensitization mechanism has still poor knowledge. Neuronal calcium sensor 1 was identified as a dopaminergic receptor interacting protein. When expressed in ...
Tópico(s): Neural and Behavioral Psychology Studies
2008 - Elsevier BV | Neurochemistry International
Jindřich Činátl, Marco Bechtel, Philipp Reus, Mélanie Ott, Florian Rothweiler, Martin Michaelis, Sandra Ciesek, Denisa Bojková,
Abstract The Mpox virus can cause severe disease in the susceptible population with dermatologic and systemic manifestations. Furthermore, ophthalmic manifestations of mpox infection are well documented. Topical trifluridine (TFT) eye drops have been used for therapy of ophthalmic mpox infection in patients, however, its efficacy against mpox virus infection in this scenario has not been previously shown. In the present study, we have established ophthalmic cell models suitable for the infection ...
Tópico(s): Immunotherapy and Immune Responses
2024 - Wiley | Journal of Medical Virology
Produção Nacional
Revisado por pares
Zuleide Maria Ignácio, Renato S. da Silva, Marcos Eduardo Plissari, João Quevedo, Gislaine Z. Réus,
Tópico(s): Circadian rhythm and melatonin
2019 - Springer Science+Business Media | Molecular Neurobiology
José Alcalde, María del Carmen Marco-Gil, José A. Silva-Reus,
As it is known, there is no rule satisfying additivity in the complete domain of bankruptcy problems. This paper proposes a notion of partial additivity in this context, to be called μ-additivity. We find out that this property, together with two quite compelling axioms, equal treatment of equals and continuity, identify the minimal overlap rule, introduced by O'Neill (Math. Soc. Sci. 2:345–371, 1982).
Tópico(s): Economic theories and models
2012 - Springer Science+Business Media | Top
Produção Nacional
Revisado por pares
Helena M. Abelaira, Gislaine Z. Réus, Karine F. Ribeiro, Amanda V. Steckert, Francielle Mina, Daniela Rosa, Cíntia V. Santana, Marco Aurélio Romano‐Silva, Felipe Dal‐Pizzol, João Quevedo,
The rats were subjected to 40 days of stress protocol, during which the sucrose consumption was assessed in rats chronically treated with lamotrigine (20 mg/kg) or with saline. The signaling cascade and oxidative stress parameters were assessed in the brain rat. Both control and stressed rats treated with lamotrigine showed an increase on malondialdehyde equivalents (MDA) in the prefrontal cortex, and that there was also an increase in the amygdala of the control rats treated with lamotrigine. The ...
Tópico(s): Neuroscience and Neuropharmacology Research
2013 - Elsevier BV | Neuroscience Research
Produção Nacional
Revisado por pares
Marco Bettine Almeida, Alessandro Soares da Silva,
Este ensaio procura discutir algumas questões relacionadas à homofobia no futebol. Para isso analisaram-se, por meio de documentos oficiais e pesquisa bibliográfica, as dificuldades e os desafios para a luta contra a homofobia no Brasil. A partir destas discussões iniciais buscou-se relacionar o mundo do “macho” e a reprodução da discriminação no futebol. Como forma de análise partiu-se de dois autores das ciências sociais, Durkheim com o conceito de anomia, que oferece uma explicação do motivo da ...
Tópico(s): Youth, Politics, and Society
2012 - Associação Sul-Rio-Grandense de Pesquisadores em História da Educação (ASPHE) | Movimento (Porto Alegre)
Mauro Dragoni, Marco Federici, Andi Rexha,
Tópico(s): Topic Modeling
2019 - Springer Science+Business Media | Cognitive Computation
Belén Alejos, Inés Suárez‐García, Marta Rava, Azucena Bautista, Félix Gutiérrez, David Dalmau, Íñigo Sagastagoitia, Antonio Rivero, Santiago Moreno, Inmaculada Jarrín, Santiago Moreno, Inmaculada Jarrín, David Dalmau, Marı́a Luisa Navarro, María Isabel González, Féderico García, Eva Poveda, José Antonio Iribarren, Félix Gutiérrez, Rafael Rubio, Francesc Vidal, Juan Berenguer, Juan González, María Ángeles Muñoz‐Fernández, Inmaculada Jarrín, Belén Alejos, Cristina Moreno, Carlos Iniesta, Luis Miguel Garcia Sousa, Nieves Sanz Perez, Marta Rava, María Ángeles Muñoz‐Fernández, Irene Consuegra Fernández, Esperanza Merino, Gema García, Irene Portilla, Iván Agea, Joaquín Portilla, José Sánchez‐Payá, Juan Carlos Rodrı́guez, L. Gimeno, Livia Giner, Marcos Díez, Melissa Carreres, Sergio Reus, Vicente Boix, Diego Torrús, Ana López Lirola, Dácil García, Felícitas Díaz-Flores, Juan Luís Gómez, M.M. Alonso, Ricardo Pelazas, Jehovana Hernández, María Remedios Alemán Valls, María Inmaculada Hernández, Víctor Asensi, Eulalia Valle-Garay, María Eugenia Rivas Carmenado, Tomás Suárez-Zarracina Secades, Laura Pérez, Rafael Rubio, Federico Pulido, Otilia Bisbal, Asunción Hernando, Lourdes Domínguez, David Rial‐Crestelo, Laura Muñoz Bermejo, Mireia Santacreu, José Antonio Iribarren, Julio Arrizabalaga, María José Aramburu, Xabier Camino, Francisco Rodríguez-Arrondo, Miguel Ángel von Wichmann, Lidia Pascual Tomé, Miguel Ángel Goenaga, Ma Jesús Bustinduy, Harkaitz Azkune, Maialen Ibarguren, Aitziber Lizardi, Xabier Kortajarena, Ma Pilar Carmona Oyaga, Maitane Umérez Igartua, Félix Gutiérrez, Mar Masiá, Sergio Padilla, Catalina Robledano, Joan Gregori Colomé, Araceli Adsuar, Rafael J. Pascual, Marta Fernández, José Alberto García, Xavier Barber, Vanessa Agullo Re, Javier García Abellán, R. Pascual Pérez, María Roca, Roberto Muga, Arantza Sanvisens, Daniel Fuster, Juan Berenguer, Juan Carlos López Bernaldo de Quirós, Isabel Gutiérrez, Margarita Ramírez, Belén Padilla, Paloma Gijón, Teresa Aldámiz‐Echevarría, Francisco Tejerina, FranciscoJosé Parras, Pascual Balsalobre, Cristina Díez, Leire Pérez‐Latorre, Chiara Fanciulli, Francesc Vidal, Joaquín Peraire, Consuelo Viladés, Sergio Veloso, Montserrat Vargas, Montserrat Olona, Anna Rull, Esther Rodríguez‐Gallego, Verónica Alba, Alfonso Javier Castellanos, Miguel López-Dupla, Marta Montero, José López Aldeguer, Marino Blanes Juliá, María Tasias Pitarch, Iván Castro Hernández, Eva Muñoz, Sandra Cuéllar Tovar, Miguel Salavert, Juan Fernández Navarro, Juan González‐García, Francisco Arnalich, José Ramón Arribas, Ignacio de los Santos, Juan Castro, Ana Delgado Hierro, Luis Escosa, Pedro Herranz, Víctor Hontañón, Silvia García‐Bujalance, Milagros García López‐Hortelano, A. M. Maceira Gonzalez, Luz Martín‐Carbonero, Mario Mayoral, María José Mellado, Rafael Micán, Rocío Montejano, MaríaLuisa Montes, Victoria Moreno, Ignacio Valero, Guadalupe Rúa Cebrián, Berta Rodés, Talía Sainz, Elena Sendagorta, Natalia Stella Alcáriz, Eulalia Valencia, José Ramón Blanco, José A. Oteo, Valvanera Ibarra, Luís Metola, Mercedes Sanz, Laura Pérez‐Martínez, Piedad Arazo, Gloria Sampériz, David Dalmau, Ángeles Jaén, Montse Sanmartí, Mireia Cairó, Javier Martínez‐Sanz, Pablo Velli, Roser Font, Marina Martínez, Francesco Aiello, M. Rivero Marcotegui, Jesús Repáraz, María Gracia Ruiz de Alda, María Teresa Cano, Beatriz Pierola Ruiz de Galarreta, María José Amengual, Gemma Navarro, Manel Cervantes Garcia, Sonia Calzado Isbert, Marta Navarro Vilasaró, Ignacio de los Santos, Jesús Sanz, Ana Salas Aparicio, Cristina Sarriá Cepeda, Lucio Garcia-Fraile Fraile, Enrique Martín Gayo, Santiago Moreno, José L. Casado, Fernando Dronda Núñez, Santiago Moreno, Maria Jesús Pérez‐Elías, Carolina Gutiérrez, Nadia Madrid, Santos del Campo, Sergio Serrano‐Villar, María Jesús Vivancos, Javier Martínez‐Sanz, Usua Anxa Urroz, Tamara Velasco, Enrique Bernal, Alfredo Cano Sánchez, Antonia Alcaraz García, Joaquín Bravo Urbieta, Ángeles Muñoz Pérez, María José Alcaraz, Maria del Carmen Villalba, Féderico García, José Hernández‐Quero, Leopoldo Muñoz Medina, Marta Álvarez, Natalia Chueca, David Vinuesa García, Clara Martinez-Montes, Carlos Guerrero Beltrán, Adolfo de SalazarGonzalez, Ana Fuentes, Jorge del Romero, Montserrat Raposo Utrilla, Carmen Rodríguez, Teresa Puerta, Juan Carlos Carrió, Mar Vera, Juan Ballesteros, Oskar Ayerdi, Antonio Antela, Elena Losada, Melchor Riera, María Luz Pintos Peñaranda, Ma Angels Ribas, Antoni A Campins, Carmen Vidal, Francisco Fanjul, Javier Murillas, Francisco Homar, Helem Vílchez, Marisa Martín, Antoni Payeras, Jesús Santos, Cristina Gómez Ayerbe, Isabel Viciana, Rosario Palacios, Carmen López, Carmen Maria Gonzalez-Domenec, Pompeyo Viciana, Núria Espinosa, Luís F. López‐Cortés, Daniel Podzamczer, Arkaitz Imaz, Juan Tiraboschi, Ana Silva, María Saumoy, Paula Prieto, Esteban Ribera, Adrián Curran, Julián Olalla, Javier Pérez Stachowski, Alfonso del Arco, Javier de la Torre, José Luís Prada, José María García de Lomas Guerrero, Onofre Juan Martínez, Francisco Jesús Vera, Lorena Martinez‐Gamboa, Josefina García, Begoña Alcaraz, Amaya Jimeno, Ángeles Castro Iglesias, Berta Pernas, Álvaro Mena de, Josefa Muñoz, Miren Zuriñe Zubero, Josu Mirena Baraia-Etxaburu, Sofía Ibarra Ugarte, Oscar Luis Ferrero Benéitez, Josefina López de Munain, Ma Mar Cámara López, Mireia de la Peña, Miriam Lopez, Iñigo López Azkarreta, Carlos Galera, Helena Albendín, Aurora Rodríguez Pérez, Asunción Iborra, Antonio Moreno, Maria Angustias Merlos, Asunción Vidal, Marisa Meca, Concha Amador, Francisco Pasquau,
Abstract Objectives We compared 48 week effectiveness and safety of first-line antiretroviral regimens. Methods We analysed HIV treatment-naive adults from the Cohort of the Spanish HIV/AIDS Research Network (CoRIS) starting the most commonly used antiretroviral regimens from 2014 to 2018. We used multivariable regression models to assess the impact of initial regimen on: (i) viral suppression (VS) (viral load <50 copies/mL); (ii) change in CD4 cell count; (iii) CD4/CD8 normalization (>0.4 and >1); ( ...
Oxford University Press
J.A.W.A. Reus, Peter Leendertse, Christian Bockstaller, Inge S. Fomsgaard, Volkmar Gutsche, Kathleen Lewis, Christer Nilsson, Luc Pussemier, Marco Trevisan, Hayo van Der Werf, Flávia Alfarroba, Sylvia Blümel, J. Isart, Dianne McGrath, Tiina Seppälä,
Information is required on pesticide risk indicators used in Europe in order to optimise their use to reduce the environmental impact of pesticides. The present study was performed to compare and evaluate eight pesticide risk indicators developed in Europe and to give recommendations for further use and harmonisation of these risk indicators. This paper is based on the results of the CAPER project (concerted action on pesticide risk indicators). First the indicators and their methodologies were characterised. ...
Tópico(s): Insect and Pesticide Research
2002 - Elsevier BV | Agriculture Ecosystems & Environment
Produção Nacional
Revisado por pares
Renan P. Souza, Eliane Cristina de Souza Soares, Daniela Rosa, Bruno Rezende Souza, Karin Martins Gomes, Samira S. Valvassori, Gislaine Z. Réus, Cecília G. Inácio, Márcio R. Martins, Marcus V. Gomez, João Quevedo, Marco Aurélio Romano‐Silva,
Abstract Dopamine may alter the phosphorylation state of DARPP‐32 that plays a central role in the dopaminergic neurons biology. Studies have shown that DARPP‐32/protein phosphatase 1 cascade is a major target for psychostimulants drugs. Methylphenidate is a psychostimulant that acts blocking the dopamine transporter has been used as an effective treatment for Attention Deficit Hyperactivity Disorder. We investigated if methylphenidate could alter DARPP‐32 expression in five brain regions (striatum, ...
Tópico(s): Bipolar Disorder and Treatment
2008 - Wiley | International Journal of Developmental Neuroscience
Produção Nacional
Revisado por pares
Amanda Gollo Bertollo, Roberta Eduarda Grolli, Marcos Eduardo Plissari, Vanessa Aparecida Gasparin, João Quevedo, Gislaine Z. Réus, Margarete Dulce Bagatini, Zuleide Maria Ignácio,
Major depressive disorder (MDD) is one of the disorders that most causes disability and affects about 265 million people worldwide, according to the World Health Organization (WHO). Chronic stress is one of the most prevalent factors that trigger MDD. Among the most relevant biological mechanisms that mediate stress and MDD are changes in the hypothalamic-pituitary-adrenal (HPA) axis function. Hypercortisolism is one of the relevant mechanisms involved in response to stress and is present in many people ...
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2020 - AIMS Press | AIMS neuroscience
Inés Suárez‐García, Marta Ruiz‐Algueró, Cristina García Yubero, Cristina Moreno, María José Belza, Miriam Estébanez, Ignacio de los Santos, Mar Masiá, G. Abad, Josefa Muñoz Sánchez, Mohamed Omar, Inmaculada Jarrín, Santiago Moreno, Inmaculada Jarrín, David Dalmau, María Luisa Navarro, Maria Gonzalez, Féderico García, Eva Poveda, José Antonio Iribarren, Félix Gutiérrez, Rafael Rubio, Francesc Vidal, Juan Berenguer, Juan González, María Ángeles Muñoz‐Fernández, Inmaculada Jarrín, Belén Alejos, Cristina Moreno, Carlos Iniesta, Luis Miguel Garcia Sousa, Nieves Sanz Perez, Marta Rava, María Ángeles Muñoz‐Fernández, Irene Consuegra Fernández, Esperanza Merino, Gema García, Irene Portilla, Iván Agea, Joaquín Portilla, José Sánchez-Pay aacute, Juan Carlos Rodrı́guez, L. Gimeno, Livia Giner, Marcos Díez, Melissa Carreres, Sergio Reus, Vicente Boix, Diego Torrús, Ana López Lirola, Dácil García, Felícitas Díaz-Flores, Juan Luís Gómez, María del Mar Alonso, Ricardo Pelazas, Jehovana Hernández, María Remedios Alemán Valls, María Inmaculada Hernández, Víctor Asensi, Eulalia Valle-Garay, María Eugenia Rivas Carmenado, Tomás Suárez-Zarracina Secades, Laura Pérez‐Martínez, Rafael Rubio, Federico Pulido, Otilia Bisbal, Asunción Hernando, Lourdes Domínguez, David Rial‐Crestelo, Laura Muñoz Bermejo, Mireia Santacreu, José Antonio Iribarren, Julio Arrizabalaga, María José Aramburu, Xabier Camino, Francisco Rodríguez-Arrondo, Miguel Ángel von Wichmann, Lidia Pascual Tomé, Miguel Ángel Goenaga, Ma Jesús Bustinduy, Harkaitz Azkune, Maialen Ibarguren, Aitziber Lizardi, Xabier Kortajarena, Ma PilarCarmona Oyaga, Maitane Umérez Igartua, Félix Gutiérrez, Mar Masiá, Sergio Padilla, Catalina Robledano, Joan Gregori Colomé, Araceli Adsuar, Rafael J. Pascual, Marta Fernández, José Alberto García, Xavier Barber, Vanessa Agullo Re, Javier García Abellán, R. Pascual Pérez, María Roca, Roberto Muga, Arantza Sanvisens, Daniel Fuster, Juan Berenguer, Juan Carlos López Bernaldo de Quirós, Isabel Gutiérrez, Margarita Ramírez, Belén Padilla, Paloma Gijón, Teresa Aldámiz‐Echevarría, Francisco Tejerina, F Parras, Pascual Balsalobre, Cristina Díez, Leire Pérez‐Latorre, Chiara Fanciulli, Francesc Vidal, Joaquín Peraire, Consuelo Viladés, Sergio Veloso, Montserrat Vargas, Montserrat Olona, Anna Rull, Esther Rodríguez‐Gallego, Verónica Alba, Alfonso Javier Castellanos, Miguel López-Dupla, MartaMontero Alonso, José López Aldeguer, Marino Blanes Juliá, María Tasias P itarch, Iván Castro Hernández, Eva Muñoz, Sandra Cuéllar Tovar, Miguel Salavert, JuanFernández Navarro, Juan González‐García, Francisco Arnalich, José Ramón Arribas, Ignacio de los Santos, Juan Castro, Ana Delgado Hierro, Luis Escosa, Pedro Herranz, Víctor Hontañón, Silvia García‐Bujalance, Milagros García López‐Hortelano, A. M. Maceira Gonzalez, Luz Martín‐Carbonero, Mario Mayoral, María José Mellado, Rafael Micán, Rocío Montejano, Marisa Montes, V. Moreno, Ignacio Valero, Guadalupe Rúa Cebrián, Berta Rodés, Talía Sainz, Elena Sendagorta, Natalia Stella Alcáriz, Eulalia Valencia, José Ramón Blanco, JoséAntonio Oteo, Valvanera Ibarra, Luís Metola, Mercedes Sanz, Laura Pérez‐Martínez, Piedad Arazo, Gloria Sampériz, David Dalmau, Ángeles Jaén, Montse Sanmartí, Mireia Cairó, Javier Martínez‐Sanz, Pablo Velli, Roser Font, Marina Martínez, Francesco Aiello, M. Rivero Marcotegui, Jesús Repáraz, María Gracia Ruiz de Alda, María Teresa Cano, Beatriz Pierola Ruiz de Galarreta, María José Amengual, Gemma Navarro, ManelCervantes Garcia, SoniaCalzado Isbert, MartaNavarro Vilasaro, Ignacio de los Santos, Jesús Sanz, Ana Salas Aparicio, Cristina Sarriá Cepeda, Lucio Garcia-Fraile Fraile, Enrique Martín Gayo, Santiago Moreno, José L. Casado, Fernando Dronda Núñez, Santiago Moreno, Maria Jesús Pérez‐Elías, Carolina Gutiérrez, Nadia Madrid, Santos del Campo, Sergio Serrano‐Villar, María Jesús Vivancos, Javier Martínez‐Sanz, Usua Anxa Urroz, Tamara Velasco, Enrique Bernal, Alfredo Cano Sánchez, Antonia Alcaraz García, Joaquín Bravo Urbieta, Ángeles Muñoz Pérez, María José Alcaraz, Maria del CarmenVillalba, Féderico García, JoséHernández Quero, Leopoldo Muñoz Medina, Marta Álvarez, Natalia Chueca, David Vinuesa García, Clara Martinez-Montes, Carlos Guerrero Beltrán, Adolfo de Salazar González, A Lázaro López, Jorge del Romero, Montserrat Raposo Utrilla, Carmen Rodríguez, Teresa Puerta, Juan Carlos Carri oacute, Mar Vera, Juan Ballesteros, Oskar Ayerdi, Antonio Antela, Elena Losada, Melchor Riera, María Luz Pintos Peñaranda, Ma Angels Ribas, Antoni A Campins, Carmen Vidal, Francisco Fanjul, Javier Murillas, Francisco Homar, Helem Vílchez, Marisa Martín, Antoni Payeras, Jesús Santos, Cristina Gómez Ayerbe, Isabel Viciana, Rosario Palacios, CarmenPérez López, Carmen Maria Gonzalez-Domenec, Pompeyo Viciana, Núria Espinosa, Luís F. López‐Cortés, Daniel Podzamczer, Arkaitz Imaz, Juan Tiraboschi, Ana Silva, María Saumoy, Paula Prieto, Esteban Ribera, Adrián Curran, Julián Olalla, JavierPérez Stachowski, Alfonso del Arco, Javier de la Torre, JoséLuis Prada, José María García de Lomas Guerrero, O.P. Martinez, Francisco Jesús Vera, Lorena Martinez‐Gamboa, Josefina García, Begoña Alcaraz, Amaya Jimeno, Ángeles Castro Iglesias, Berta Pernas, A.C. Micheletti Gomide Nogueira de, Josefa Muñoz, MirenZuriñe Zubero, Josu Mirena Baraia-Etxaburu, Sofía Ibarra Ugarte, Oscar LuisFerrero Beneitez, Josefina López de Munain, Ma Mar Cámara López, Mireia de la Peña, Miriam Lopez, Iñigo López Azkarreta, Carlos Galera, Helena Albendín, Aurora Rodríguez Pérez, Asunción Iborra, Antonio Moreno, MariaAngustias Merlos, Asunción Vidal, Marisa Meca,
To assess the attitudes and opinions about generic antiretroviral drugs (ARVs) and single-tablet regimen (STR) de-simplification among physicians prescribing HIV treatment in the cohort of the Spanish HIV/AIDS Research Network (CoRIS).An online questionnaire with 27 structured questions was sent to all physicians (n=199) who prescribed ARVs among the 45 centres participating in the cohort.A total of 169 (84.9%) physicians answered the questionnaire. Only 4.1% of the physicians would never prescribe generic ...
Oxford University Press
Marqueta, Bárbara, López-Cortés, Natalia y Ariño-Bizarro, Andrea (eds) (2022). Avances de la Lingüística y su aplicación didáctica. AKAL. 256 páginas. ISBN: 978-84-460-5186-2.
Tópico(s): Educational Technology in Learning
2025 - | ELUA Estudios de Lingüística Universidad de Alicante
Produção Nacional
Revisado por pares
Gislaine Z. Réus, Samira S. Valvassori, Hellen Nuernberg, Clarissa M. Comim, Roberto B. Stringari, Peterson Teodoro Padilha, Daniela Dimer Leffa, Priscila Tavares, Gracilene Dagostim, Marcos Marques da Silva Paula, Vanessa Moraes de Andrade, João Quevedo,
Malathion is an insecticide widely used in agriculture and in public health programs that when used indiscriminately in large amounts can cause environmental pollution and risk to human health. However, it is possible that during the metabolism of malathion, reactive oxygen species can be generated, and malathion may produce oxidative stress in intoxicated rats that can be responsible for alterations in DNA molecules related in some studies. As a result, the present study aimed to investigate the ...
Tópico(s): Pesticide and Herbicide Environmental Studies
2008 - American Chemical Society | Journal of Agricultural and Food Chemistry