Cátia Gonçalves, Marta Martins, Mário Diniz, Maria Helena Costa, Sandra Caeiro, Pedro M. Costa,
Within an environmental risk assessment framework of a moderately contaminated estuary (the Sado, SW Portugal), the present work intended to detect endocrine disruption in a flatfish, Solea senegalensis Kaup, 1858, and its potential relationship to organic toxicants. Animals were collected from two distinct areas in the estuary (industrial and rural) and from an external reference area. Hepatic vitellogenin (VTG) levels, cytochrome P450 (CYP1A) induction, ethoxyresorufin-O-deethylase (EROD) activity ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2014 - Elsevier BV | Marine Environmental Research
Osvaldo Marinotti, Gustavo Cerqueira, Luiz Gonzaga Paula de Almeida, Maria Inês Tiraboschi Ferro, Élgion L. S. Loreto, Arnaldo Zaha, Santuza Maria Ribeiro Teixeira, Adam R. Wespiser, Alexandre de Almeida e Silva, Aline Daiane Schlindwein, Ana Carolina Landim Pacheco, Artur Silva, Brenton R. Graveley, Brian P. Walenz, Bruna de Araújo Lima, Carlos Ribeiro, Carlos Gustavo Nunes-Silva, Carlos Roberto Carvalho, Célia Maria de Almeida Soares, Cláudia Beatriz Afonso de Menezes, Cleverson C. Matiolli, Daniel R. Caffrey, Demétrius A. M. Araújo, Diana Oliveira, Douglas T. Golenbock, Edmundo C. Grisard, Fabiana Fantinatti‐Garboggini, Filomena Marino Carvalho, Fernando Gomes Barcellos, Francisco Prosdocimi, Gemma E. May, Gilson Martins de Azevedo, Giselle Moura Guimarães-Marques, Gustavo H. Goldman, Itácio Queiroz de Mello Padilha, Jacqueline da Silva Batista, Jesus Aparecido Ferro, José M. C. Ribeiro, Juliana Lopes Rangel Fietto, Karina Maia Dabbas, Louise Cerdeira, Lucymara Fassarella Agnez‐Lima, Marcelo Brocchi, Marcos Oliveira de Carvalho, Marcus de Melo Teixeira, Maria de Mascena Diniz Maia, Maria Helena S. Goldman, Maria Paula Cruz Schneider, Maria Sueli Soares Felipe, Mariangela Hungría, Marisa Nicolás, Maristela Pereira, Martín Alejandro Montes, Maurício Egídio Cantão, Michel Vincentz, Míriam Silva Rafael, Neal Silverman, Patrícia Hermes Stoco, Rangel Celso Souza, Renato Vicentini, Ricardo T. Gazzinelli, Rogério de Oliveira Neves, Rosane Silva, Spartaco Astolfi‐Filho, Talles Eduardo Ferreira Maciel, Turán P. Ürményi, Wanderli Pedro Tadei, Erney P. Camargo, Ana Tereza Ribeiro de Vasconcelos,
Anopheles darlingi is the principal neotropical malaria vector, responsible for more than a million cases of malaria per year on the American continent. Anopheles darlingi diverged from the African and Asian malaria vectors ∼100 million years ago (mya) and successfully adapted to the New World environment. Here we present an annotated reference A. darlingi genome, sequenced from a wild population of males and females collected in the Brazilian Amazon. A total of 10 481 predicted protein-coding genes ...
Tópico(s): Insect Resistance and Genetics
2013 - Oxford University Press | Nucleic Acids Research
Produção Nacional
Revisado por pares
Rosimeire Aparecida Mendes Lopes, Denise Diniz Macedo, María Helena Baena de Moraes Lopes,
Este trabalho levanta diagnósticos de enfermagem mais freqüentes, a partir do histórico de enfermagem e procedimento médico, com o objetivo de subsidiar a assistência no Serviço de Enfermagem em Oncologia do Centro de Atenção Integral à Saúde da Mulher (CAISM). Os cinco diagnósticos mais freqüentes foram: potencial para infecção, potencial para temperatura corporal alterada, potencial para aspiração e constipação colônica do padrão trocar, e potencial para intolerância à atividade do padrão mover. ...
Tópico(s): Women's cancer prevention and management
1997 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem
Produção Nacional
Revisado por pares
Bruno Tardelli Diniz Nunes, Maria Helena Rodrigues de Mendonça, Darlene de Brito Simith, Adriana Freitas Moraes, Carla Conceição Cardoso, Ivy Tsuya Essashika Prazeres, Ana Alice de Aquino, Alessandra da Conceição Miranda Santos, Alice Louize Nunes Queiroz, Daniela Sueli Guerreiro Rodrigues, Régis B Andriolo, Elizabeth Salbé Travassos da Rosa, Livia Carício Martins, Pedro Fernando da Costa Vasconcelos, Daniele Barbosa de Almeida Medeiros,
Hantavirus Pulmonary Syndrome is an, often fatal, emerging zoonotic disease in the Americas caused by hantaviruses (family: Hantaviridae). In Brazil, hantavirus routine diagnosis is based on serology (IgM-ELISA) while RT-PCR is often used to confirm acute infection. A Semi-nested RT-PCR and an internally controlled RT-qPCR assays were developed for detection and quantification of four hantaviruses strains circulating in the Brazilian Amazon: Anajatuba (ANAJV) and Castelo dos Sonhos (CASV) strains of ...
Tópico(s): Viral Infections and Outbreaks Research
2019 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Pedro Z. de Moraes, Pedro Diniz, Maria Helena Constantino Spyrides, Daniel Marques Almeida Pessoa,
Abstract Primates' predators, such as carnivore mammals, usually rely on camouflage to increase proximity to prey and start a predatory attempt. Camouflage depends not only on the color pattern presented by a predator's pelage but also on the background scene in which the hunting takes place. Another factor that influences camouflage effectiveness is prey's color vision since a given camouflage strategy might not work for all visual phenotypes. Still, little research has been made on the effect ...
Tópico(s): Olfactory and Sensory Function Studies
2021 - Wiley | American Journal of Primatology
Pedro M. Costa, Tiago Repolho, Sandra Caeiro, Mário Diniz, Isabel Moura, Maria Helena Costa,
Metallothionein (MT) in the liver of gilthead seabreams (Sparus aurata L., 1758) exposed to Sado estuary (Portugal) sediments was quantified to assess the MT induction potential as a biomarker of sediment-based contamination by copper (Cu), cadmium (Cd), lead (Pb) and arsenic (As). Sediments were collected from two control sites and four sites with different levels of contamination. Sediment Cu, Cd, Pb, As, total organic matter (TOM) and fine fraction (FF) levels were determined. Generalized linear models ( ...
Tópico(s): Heavy metals in environment
2007 - Elsevier BV | Ecotoxicology and Environmental Safety
Produção Nacional
Revisado por pares
Simone Grilo Diniz, Debra Bick, Maria Helena Bastos, María Luiza Gonzalez Riesco,
Brazil is a middle-income country, with a fertility rate of 2·1 children per woman, and a health-care system that guarantees universal free access—the Sistema Único de Saúde (SUS). It has vibrant social organisations, in which activists from the feminist movement have influenced the development and implementation of progressive national women's health policies. Hospital births account for 96% of all births (and more than 99% in urban areas). Despite increases in investment in health-care provision, ...
Tópico(s): Global Health and Epidemiology
2007 - Elsevier BV | The Lancet
Marta Martins, José M. Santos, Mário Diniz, Ana Ferreira, Maria Helena Costa, Pedro M. Costa,
Polycyclic aromatic hydrocarbons (PAHs) are priority environmental mutagens and carcinogens that occur in the aquatic environment as mixtures rather than the individual compounds for which guidelines are issued. The present work aimed at understanding the interaction effects between carcinogenic and non-carcinogenic PAHs in a model marine fish (Dicentrarchus labrax) in realistic scenarios. Laboratory assays under ecologically-relevant parameters were conducted for 28 days with sediments spiked with ...
Tópico(s): Sulfur Compounds in Biology
2015 - Elsevier BV | Environmental Research
Produção Nacional
Revisado por pares
Ismelinda Maria Diniz Mendes Souza, Helena Borges Martins da Silva Paro, Rogério Rizo Morales, Rogério de Melo Costa Pinto, Carlos Henrique Martins da Silva,
This is a descriptive, cross-sectional study aimed at investigating the health-related quality of life (HRQoL) of nursing students and its relationship with year of training, sociodemographic variables and the intensity of depressive symptoms. A convenience sample of 256 students, out of 353 eligible (72%), responded to the Medical Outcomes Study - The 36 Item Short-Form Health Survey (SF-36) and the Beck Depression Inventory (BDI) (self-administered). Final-year students, females and students with a higher ...
Tópico(s): Health, psychology, and well-being
2012 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem
Produção Nacional
Revisado por pares
Jociani Ascari, Sérgio Dracz, Flávio Alves Santos, Josefa Abucáter Lima, Maria Helena Glicério Marcelina Diniz, Eugênia Azevedo Vargas,
A quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous analyses of malachite green (MG), crystal violet (CV) and its major metabolites, leucomalachite green (LMG) and leucocrystal violet (LCV) residues in fish and shrimp samples has been validated. Fish and shrimp samples were extracted with citrate buffer/acetonitrile, and the extracts were purified on strong cation-exchange (SCX) solid-phase extraction (SPE) cartridge. After conversion of LMG into MG using ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2012 - Taylor & Francis | Food Additives & Contaminants Part A
Produção Nacional
Revisado por pares
Olga Moraes Toledo, Delly Oliveira Filho, Antônia Sônia Alves Cardoso Diniz, José Helvecio Martins, María Helena Murta Vale,
The availability of reliable energy sources for all people, especially electricity, indicates an imbalance in the living conditions of a society. Therefore, new systems must be implemented to couple energy storage and renewable energy generation for the grid reliability improvement and increase access to electricity. This paper proposes a methodology to establish a general index focused on the insertion of distributed photovoltaic generation and energy storage using batteries. This methodology was ...
Tópico(s): Power System Optimization and Stability
2012 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Power Systems
Produção Nacional
Revisado por pares
Lílian Martins Oliveira Diniz, Helena Duani, Camila Rodrigues Freitas, Rosângela Maria de Figueiredo, Christovão Castro Xavier,
Visceral leishmaniasis is a severe and potentially fatal vector-borne disease. The most typical symptoms are fever, hepatosplenomegaly, weight loss, bleeding and bacterial infections. Neurological changes are rarely reported. This paper describes a child who presented with neurological signs as the first symptoms of leishmaniasis; tone was diminished and tremors in the extremities were observed. A diagnosis of visceral leishmaniasis was confirmed by parasite detection in the bone marrow. Symptoms ...
Tópico(s): Trypanosoma species research and implications
2010 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Rafael Loch Batista, Elisa Verduguez, Marlene Inácio, Flávia Siqueira Cunha, Mateus Diniz Marques, Natália Lisboa Rosa Almeida Gomes, José Antônio Diniz Faria, Maria Helena Palma Sircili, Berenice B. Mendonça, Elaine Maria Frade Costa, Sorahia Domenice,
Objective Discrimination and bullying are common conditions among LGBT people. During schooling, these practices compromising education. The aim of this study is to evaluate educational attainment among Brazilian transgender women (TW) and how their education level affects the risk of HIV infection. Study design a cross-sectional population-based study. Subjects and methods 95 adult TW were selected. Information concerning verbal and physical aggression, school dropout, school years (SY), and educational ...
Tópico(s): Sex work and related issues
2020 - Brazilian Society of Endocrinology and Metabolism | Archives of Endocrinology and Metabolism
Tânia S.C.R. Rebelo, João Paulo Noronha, M. Galésio, Hugo M. Santos, Mário Diniz, M. Goreti F. Sales, Maria Helena Fernandes, João Costa‐Rodrigues,
Prostate Specific Antigen (PSA) is widely used as a biomarker for prostate cancer. Recently, an electrochemical biosensor for PSA detection by means of molecularly imprinted polymers (MIPs) was developed. This work evaluated the performance and the effectiveness of that PSA biosensor in screening the biomarker PSA in biological media with complex composition, collected from different human prostate cell line cultures. For that, the prostate cancer LNCaP and PC3 cells, and the non-cancerous prostate ...
Tópico(s): Mass Spectrometry Techniques and Applications
2015 - Elsevier BV | Materials Science and Engineering C
Miguel Larguinho, Pedro M. Costa, Gonçalo Sousa, Maria Helena Costa, Mário Diniz, Pedro V. Baptista,
ABSTRACT Acrylamide is an amide used in several industrial applications making it easily discharged to aquatic ecosystems. The toxicity of acrylamide to aquatic organisms is scarcely known, although previous studies with murine models provided evidence for deleterious effects. To assess the effects of acrylamide to freshwater fish, goldfish ( Carassius auratus L.) were exposed to several concentrations of waterborne acrylamide and analysed for genotoxic damage, alterations to detoxifying enzymes and ...
Tópico(s): Carcinogens and Genotoxicity Assessment
2013 - Wiley | Journal of Applied Toxicology
Produção Nacional
Revisado por pares
Otávio Augusto Soares Machado, Vinícius Leonardo Sousa Diniz, Maria Elizabeth Pereira Passos, Heloisa Helena de Oliveira, Laiane Cristina dos Santos-Oliveira, Amanda Lins Alecrim, Tiago Bertola Lobato, Richelieau Manoel, Ilana Souza Correa, Eliane B. Silva, Sarah de Oliveira Poma, Mariana Mendes de Almeida, Tânia Cristina Pithon‐Curi, Susana Nogueira Diniz, Adriana Cristina Levada‐Pires, Rui Curi, Laureane Nunes Masi, Sandro Massao Hirabara, Renata Gorjão,
What is the central question of this study? Is lymphocyte DNA methylation differentially modulated by resistance training and aerobic exercise in older women? What is the main finding and its importance? The practice of resistance training led to an increased global DNA methylation in lymphocytes. The exercise-induced increase of inflammatory genes methylation may be associated with immune function impairment during ageing.Ageing-induced increase in inflammatory gene expression through a reduction ...
Tópico(s): IL-33, ST2, and ILC Pathways
2021 - Wiley | Experimental Physiology
Produção Nacional
Revisado por pares
Ana Francisca Vaz, Denise Diniz Macedo, Édina Tavares de Lima Montagnoli, María Helena Baena de Moraes Lopes, Regina Célia Grion,
É meta de nosso serviço sistematizar a assistência de enfermagem a clientes portadoras de câncer genital e mamário, submetidas a tratamento ambulatorial em radioterapia, através do processo de enfermagem, utilizando-se, na fase diagnóstica, a taxionomia da North American Nursing Diagnosis Association (NANDA) e os problemas colaborativos. Foram elaboradas fichas que permitissem o registro de forma sucinta e completa dos dados mais relevantes para a assistência de enfermagem, contendo: anamnese, orientações ...
Tópico(s): Nursing Diagnosis and Documentation
2002 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem
Hugo M. Santos, Mário Diniz, Pedro M. Costa, I. Peres, Maria Helena Costa, Sheila Alves, José Luís Capelo,
Contamination of aquatic environments by arsenic is a serious worldwide problem. The main objective of this work was to evaluate the response of a freshwater clam (Corbicula fluminea) to arsenic (As III) exposure and infer its potential as a biological indicator of contamination. Metallothioneins (MTs) were used as indicators of metalloid toxicity in combination with an histological and histochemical evaluation. After a period of acclimatization in the laboratory, 50 C. fluminea (0.4 g +/- 0.1) were exposed ...
Tópico(s): Arsenic contamination and mitigation
2007 - Wiley | Environmental Toxicology
Produção Nacional
Revisado por pares
Marina Gonçalves Diniz, G.A. Soares, Maria João Coelho, Maria Helena Fernandes,
Tópico(s): Dental Implant Techniques and Outcomes
2002 - Springer Science+Business Media | Journal of Materials Science Materials in Medicine
Produção Nacional
Revisado por pares
Mayra Manoella Perez, Juliana Souza Pessoa, Ana Lídia Ciamponi, Michèle Baffi Diniz, Maria Teresa Botti Rodrigues Santos, Heloisa Helena de Oliveira, Renata Gorjão, Renata de Oliveira Guaré,
Obesity is considered a risk factor for periodontal health due to the low- grade inflammation promoted by the increased adipose tissue. Objective: This study aimed to determine correlations and associations between gingival inflammation (Simplified Oral Hygiene Index, and Gingival Index), salivary immunoglobulin A (s-IgA), and salivary parameters (salivary flow and osmolality) in normal-weight and overweight/obese children. Material and Methods: Ninety-one children, aged 6 to 12 years old (8.6±1.9 years), ...
Tópico(s): Diabetes and associated disorders
2018 - UNIVERSIDADE DE SÃO PAULO | Journal of Applied Oral Science
Produção Nacional
Revisado por pares
Isaura Isabelle Fonseca Gomes da Silva, Hildson Dornelas Angelo, Eliézer Rushansky, Maria Helena Queiroz de Araújo Mariano, Maria de Mascena Diniz Maia, Paulo Roberto Eleutério de Souza,
Tópico(s): Rheumatoid Arthritis Research and Therapies
2017 - Springer Science+Business Media | Archivum Immunologiae et Therapiae Experimentalis
Produção Nacional
Revisado por pares
Marcela Silva Lima, Carolina Maria Fontes Ferreira Nader, Letícia Paiva Franco, Zilda Maria Alves Meira, Flávio Diniz Capanema, Roberto Eustáquio Santos Guimarães, Helena Maria Gonçalves Becker,
Adenotonsillar hyperplasia (ATH) and allergic rhinitis (AR) are the most common causes of upper airway obstruction in children. Such diseases, by affecting the upper airways, can cause chronic alveolar hypoventilation, pulmonary vasoconstriction and pulmonary hypertension, which in some cases, are irreversible.
Tópico(s): Tracheal and airway disorders
2016 - Elsevier BV | Brazilian Journal of Otorhinolaryngology
António Morais, Bruno Lima, Maria Gabriela Campolina Diniz Peixoto, Natália Melo, Helena Alves, J Marqués, Luís Delgado,
A recent genome-wide association study detected a protective effect for the annexin A11 rs1049550*T allele (R230Cvariant) in susceptibility to sarcoidosis. We evaluated the association between rs1049550 C/T and sarcoidosis susceptibility, distinct disease phenotypes and evolution in a Portuguese population. We performed a case-control study of 208 patients and 197 healthy controls. Samples were genotyped for rs1049550 C/T using real-time polymerase chain reaction. The frequency of the annexin A11 ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2013 - Wiley | Tissue Antigens
Produção Nacional
Revisado por pares
M. L. Chizzotti, Sebastião de Campos Valadares Filho, Maria Ignês Leão, Rilene Ferreira Diniz Valadares, Fernanda Helena Martins Chizzotti, Karla Alves Magalhães, Marcos Inácio Marcondes,
Quatro novilhos holandeses fistulados no rúmen, com peso médio de 259 kg, foram distribuídos em um quadrado latino 4 x 4 para se avaliar o efeito dos níveis de casca de algodão na dieta de novilhos sobre o consumo e as digestibilidades totais, ruminais e intestinais de matéria seca (MS), matéria orgânica (MO), extrato etéreo (EE), proteína bruta (PB), fibra em detergente neutro corrigida para cinzas e proteína (FDNcp) e carboidratos não-fibrosos corrigidos (CNFcp) e o consumo de nutrientes digestíveis ...
Tópico(s): Soil Management and Crop Yield
2005 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Produção Nacional
Revisado por pares
Ana Virgínia Matos Sá Barreto, Vinícius Martins ALECRIM, Tibério Batista de Medeiros, Ana Lúcia Coutinho Domingues, Edmundo Pessoa Lopes, João Roberto Maciel Martins, Helena B. Nader, George Tadeu Nunes Diniz, Sílvia Maria Lucena Montenegro, Clarice Neuenschwander Lins de Morais,
- Periportal fibrosis is the major pathological consequence of the Schistosoma mansoni infection.- To evaluate the accuracy of serum markers and to construct an index to assess fibrosis.- Patients (n=116) with schistosomiasis were evaluated by ultrasound scan and measurements of serum levels of aminotransferases, γ-glutamyl transferase, alkaline phosphatase, hyaluronic acid, cytokines and platelets. Ultrasound images were used to evaluate the fibrosis using Niamey's classification and identified 19 patients ...
Tópico(s): Liver Diseases and Immunity
2017 - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) | Arquivos de Gastroenterologia
Mário Diniz, Hugo M. Santos, Pedro M. Costa, I. Peres, Maria Helena Costa, José Luís Capelo,
The main objective of this work was to evaluate arsenic effects on metallothionein (MT) induction by exposing a freshwater Asiatic clam (Corbicula fluminea) to different concentrations of this metalloid. The presence of MT-like proteins was detected by sodium dodecyl sulfate polyacrylamide gel electrophoresis and compared with a standard rabbit MT. In addition, the polarographic response showed good correspondence between standard MT and MT-like curves from C. fluminea, allowing MT quantification. ...
Tópico(s): Heavy Metal Exposure and Toxicity
2007 - Taylor & Francis | Biomarkers
Produção Nacional
Revisado por pares
Adrislaine S. Mansano, Raquel Aparecida Moreira, Hugo Carlos Dornfeld, Lia Gracy Rocha Diniz, Eny María Vieira, Michiel A. Daam, Odete Rocha, Mirna Helena Regali Seleghim,
Tópico(s): Pesticide Exposure and Toxicity
2016 - Springer Science+Business Media | Environmental Science and Pollution Research
Produção Nacional
Revisado por pares
Este estudo procura analisar o impacto causado no direito brasileiro pela Lei n. 13.146/2015 no que atina à tormentosa questão da capacidade do portador de deficiência e das medidas protetivas extraordinárias, que são a curatela e a tomada de decisão apoiada, procurando ressaltar o respeito à dignidade do deficiente como ser humano e à sua autonomia da vontade, em busca de sua inclusão social, provocando, para tanto, uma revolucionária reconstrução da teoria das incapacidades.
Tópico(s): Social and Political Issues
2016 - UNIVERSIDADE NOVE DE JULHO | Revista Thesis Juris
Produção Nacional
Revisado por pares
Maria Helena Bastos, Simone Grilo Diniz, María Luiza Gonzalez Riesco, Sônia Maria Junqueira Vasconcellos de Oliveira,
there is a consensus that the adoption of evidence-based practice contributes to the improvement of maternity care. Iranian National Guidelines for Normal Childbirth included evidence-based practice and were disseminated to hospitals in 2006 but little is known about the success of implementation. This study investigates the provision of care during labour and childbirth in comparison with national guidelines in four public hospitals in Tehran.this was a descriptive evaluation study and investigated ...
Tópico(s): Maternal and Perinatal Health Interventions
2007 - Elsevier BV | Midwifery
Produção Nacional
Revisado por pares
Luciana Diniz Nagem Janot de Matos, Giulliano Gardenghi, Maria Urbana Pinto Brandão Rondon, Helena Nogueira Soufen, A Tirone, Antônio Carlos Pereira Barretto, Patrı́cia C. Brum, Holly R. Middlekauff, Carlos Eduardo Negrão,
The long-term effects of carvedilol on muscle sympathetic nerve activity (MSNA) and muscle blood flow at rest and exercise in patients with chronic heart failure (CHF) remain unknown.Twenty-six patients (New York Heart Association class II-III) were randomized to carvedilol or placebo. Blood pressure, heart rate, MSNA, and forearm vascular resistance (FVR) at rest and during isometric forearm exercise (10% and 30% maximal voluntary contraction) were assessed before and after 6 months. Seven patients ...
Tópico(s): Cardiac Health and Mental Health
2004 - Elsevier BV | Journal of Cardiac Failure