Andrew Robson, Phil Yates, Lynne Greenwood, Keith Robotham, Andrew Pierce, DJM, Neelam Verjee, Zahid Hussain, Adam Sherwin Media Reporter, Greg Hurst Political Correspondent, Frances Gibb Legal Editor, Gary Duncan, Simon Barnes, Robert Thicknesse, Mark Souster, Caroline Merrell and Abigail Rayner, Richard Hobson, Ivo Tennant, Peter Riddell, Robert Thomson and Philip Webster, Philip Howard, Carol Midgley, David Chater, James Bone, James Ducker, Nic Hopkins, Clive Davis, Lorna Blackwood, Philip Webster, Peter Riddeli and Greg Hurst, Tim Leighton, Richard Irving, Gabrielle Starkey, Catherine Riley Property Editor, Patrick Kidd, Bob Stanley, Louis Le Bailly, Joe Goss, James Hider, Joe Joseph, Andrew Norfolk, Juilan Muscat, Ben Webster Transport Correspondent, Pat Gibson, Leo McKinstry, Peregrine Worsthorne, R. W. Eaton, Anthony Browne, Steve Bird, Dominic Walsh, Rory Watson, Tim Reid, Rosemary Bennett, Dan Sabbagh, Dalya Alberge Arts Correspondent, Richard Ford Home Correspondent, Adam Wild, John Honnor, Michael Tillotson, Scott Murdoch, Pamela Osler, Anthony Jacobs, Susan Emmett, Luke Clancy, Nick Tyler, Russell Kempson, John Price, W. S. Becket, Gary Duncan Economics Editor, Oliver Kay, Gerard Baker, David Vinter, Sarah Vine, John Westerby, Tom Baldwin, Mark Henderson Science Correspondent, Jill Sherman Whitehall Editor, Sam Coates, Ann Treneman, Sophie Kirkham and Stewart Tendler, Simon de Bruxelles, Geoffrey Dean, Sarah Marks, Alan M. Pardoe, Malvern, Marcus Binney, Raymond Keene, Vaughan Freeman, Matthew Pryor, Matt Dickinson, Christine Buckley Industrial Editor, Peter Allen, Sean O'Neill, Kaveh Solhekol, Caroline Merrell, Clifford Coonan, Chris Campling, Patrick Hosking, Damian Whitworth, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, Terry Maher (Author), Peter Dixon, Gabriel Rozenberg Economics Reporter, Nick Hasell, Jack Rowell, David Hands Rugby Correspondent, Paul Simons, John Allison, Nick Szczepanik, John Goodbody, David Charter and Rosemary Bennett, Mary Ann Sieghart, Jonathan Clayton, Tom Cox, Chirs Kilkenny, Brian MacArthur, Jane Shilling, Ian Johns, L. H. Morgan, Matthew Parris, Raymond Berger, George Caulkin, Robert Richardson, Marc Chanfield-Adams, Neil Fisher, Alan Lee, Tim Martin, Peter Riddell, John Batten, Jeremy Hart, Peter Shapiro, Richard Beeston, Joe Haines (Press Secretary), Lucia van der Post, Graham Searjeant, David Sinclair, Simon Jenkins, Richard Irving and Scott Murdoch, Mark Henderson, Martin Waller, Michael Horsnell, Chris Ayres, Gary Duncan and Gabriel Rozenberg, Carl Mortished International Business Editor, Nigel Hawkes Health Editor, Sarah Butler, Ashling O'Connor, Dr Thomas Stuttaford, Stephen Dalton, Richard Morrison, Alice Miles, Abigail Rayner, Martyn Thomas, P. J. Barker, Alexandra Blair Education Correspondent, Owen Slot, Jenny Davey, Peter Klinger, Ross Anderson, Sam Lister Health Correspondent, Patience Wheatcroft, Paul Marsden, Christopher Irvine, Elizabeth Judge Telecoms Correspondent, Damian Barr, Jayne Dowle, Stephen Pollard,
... become mainstays of the British folk music repertoire Maria Schell Austrian-born actress whose preference for playing troubled ...
2005 - Gale Group | TDA
Gastón Delpech, Gisela Pourcel, Celia María Schell, María De Luca, Juan Ángel Basualdo Farjat, Judith Celina Bernstein, Silvia Grenóvero, Mónica Sparo,
Enterococci are part of the indigenous microbiota of human gastrointestinal tract and food of animal origin. Enterococci inhabiting non-human reservoirs play a critical role in the acquisition and dissemination of antimicrobial resistance determinants. The aim of this work was to investigate the antimicrobial resistance in Enterococcus faecalis and Enterococcus faecium strains recovered from artisanal food of animal origin. Samples of goat cheese (n = 42), cow cheese (n = 40), artisanal salami (n = 30), ...
Tópico(s): Oral microbiology and periodontitis research
2012 - Mary Ann Liebert, Inc. | Foodborne Pathogens and Disease
Devon Loch, Waldemar Januszczak, Christine McGourty, David Mills, Sally Brock, Michael Burleigh, Jonathan Cox, Jonathan Miller, Gareth Walsh, Ferdinand Mount, Neil Wormald, Julius Mindel, Martin James, Rosie Millard, Michael Burke, Chris Murray, David Hewson, Hugh Canning, Andrew Stone, Peter Kemp, Alan Sweetman, Sarah Dempster, Paul Colver Dudley, Rob Clarke, Nicky Clarke, Stuart Andrew, Julian Rendell, Nicholas Hellen, Sally Jones, Professor Gideon Gerter, Alicia Wyllie, Dominic Prince, Hugh McLlvanney, Blower, Henry Partridge, Mimi Spencer, Brent Stevens, Sir Derek Higgs, Jim Irvin, Harold Emert, David Collier, Michael Wright, Nick Rennison, Sandra Towers, Bryan Appleyard, Burlington Bertie, John Elliott, Maurice Chittenden, Brian Elkind, Jillian Hogg, Helen Mound, Matthew Campbell, John Carey, Nick Fielding, Philip Pangalos, Louise de Bernières, Joan Bates, Peter Schmeichel, Graham Norwood, Christopher Higgins, David Budworth, William Lewis Business editor, Marcia MacLeod, Mike Hammond, Dr George Cook, Susannah Price, Sarah Baxter, Victoria Stanley, Ed Hughes, Joe Watson, Jason Dawe, Sian Griffiths, Richard Williams, Michael Durack, Jonathan Northcroft, Jim, Matthew Wall, David Ellis, N J, Charles Masters, Jim Munro, Peter Whittle, Tom Costello, Andrew Longmore, Patrick O'Farrell, Aaron, Qamar Ahmed, Caroline Brannigan, Steven Poole, Richard Green, E P, Andrew Sullivan, Clive Davis, Andrew Tweddle, Brian Johnson-Thomas, Geraldine Hackett, Nick Speed, Rex Garton, David Bond, Alasdair Reid, Martin Harrison, Victoria Segal, Edward Porter, Lincoln, Fergus Garrett, Dave Pollard, Yahya Birt, David Eimer, Pam Barren, Adam Nathan, Tony Blair, Shelley von Strunckel, Robin Scott-Elliot, Christopher Silvester, Paul Donovan, Grae Hillary, Steve Boyd, Barry Geraghty, John Follain, Phil Barker, David Leppard, Bane Dugdale, Jesus Antonio, Gareth Huw Davies, Lee Purcell, David Cracknell, Michael Keary, Diana Wright, Peter Koenig, Mike Futter, Stefan Volak, Natalie Graham, David Walsh, Jack Grimston, Stephen Armstrong, Bethan Cole, Richard Woods, Kenneth Smeaton, Scarlet Lancaster, Ray Hutton, David, Margaret Walters, Dileep Premachandran, Mike Wilson, A A Gill, Brian Glanville, Chrissy Iley, Humayun Gauhar, David Foster, Nigel Powell, Sarah Kate-Templeton, Daniel Emery, Roger Dobson, Rebecca Hoar, Brian Doogan, Ben Dowell, John Aizlewood, Clifford Bishop, Jeremy Lazell, Jonathan Futrell, Hugh Pearman, Tony Perrottet, Rhys Lloyd, Ted Tuckerman Chairman, Jason Robinson, John Dugdale, Barbara Hall, Aminatta Forna, Nigel Botherway, Rob Hughes, John Peter, Martin Pipe, Katie Samuel, Jane Mulkerrins, Susan d'Arcy, William Haines, Ghulam Hasnaln, David Gower, David Smith, Tim Richards, Sal Romaguera, John O'Brien, Tom Walker, Tom English, Lawrence Dallaglio, Charles Pasternak, Gareth Edwards, Shannon Porter, Duncan Brown assistant director-general, Stewart Lee, Peter Conradi, Valentina Harris, Michael Portillo, Patricia Nicol, Lawrence Sutton, Jeremy Guscott, Christine Toomey, David Alexander, Vincent Crump, Clarkson Verdict, Chris Woodhead, Goorge Davis, Martin Ellis, A Ginsberg, Mark Edwards, Rachel Bridge, Susan Clark, Raymond Keene, Zoe Brennan, Marie Colvin, Stephen Jones, Louise Armitstead, Nick Cain, Edwina Currie, Tim Moorey, Jonathan Leake Environmen Editor, Trevor Lewis, Max John, Victoria O'brien, Roland White, Richard Rae, Mark Franchetti, Jon Ungoed-Thomas, David Varney, Susan Douglas, Michael Sheridan, Barry Collins, Dipesh Gadher, John Waples, Jeremy Hart, Ann Clwyd, Ros Dodd, Lois Wilson, Stephen Pettitt, Maria McErlane, Terry Willett, Benita Eisler, Mrs Ross Yousouf, Andrew Frankel, Joe Lovejoy, Dan Cairns, David Smith Economics Editor, Patricia Grey, James Luckhurst, Tanni Grey-Thompson, Dominic Rushe, Steven Shukor, Helena Frith Powell, Philip Norman, Helen Davies, Sue Heaney, Jonny, Diego Rincon, Martin Dugdill, Robin Eggar, Frank Whitford, Kathryn Cooper, P D, David Cohen, Andrew Porter, Catherine Moye, Justin Carty, Tony Allen-Mills, Simon Wilde, Robert Sandall, Robert Winnett, Irwin Stelzer, Peter Wilson, David Dougill, Joe Lovejoy football Correspondent, Rob Maul, Steve Davies, Simon Ritter, Margarette Driscoll, Jeremy Clarkson, David Cairns, Lydia Slater, Rose Shepherd, Paula Robinson, Chris Johnston, Paul Ham, Roger Eglin, Stefan Stern, Lucinda Kemeny, Jasper Gerard, Paul Driver, Michael Woodhead, Ian Hawkey, Lisa Grainger, Phil Baker, C L, Rod Liddle, Cosmo Landesman, Gavin Conway, P J O'Rourke, Dominic O'Connell, Brian Doogan Specialist Correspondent of the Year, Caroline Donald, Philip Griffin, Miranda Seymour, Chris Humphrey, Mark Foster, Colin McDowell, Anya Hindmarch, Christopher Goodwin, Steward Lee, Yuba Bessaoud, Judith O'Reilly, Jonathan Leake, Amanda Craig, Clare Francis, John Harlow, Danniella Blonde, Claudia Croft, Sally Kinnes, Naomi Caine, David Wickers, Alessandro Severi, Clifford Hudson, Peter Almond, Minette Marrin, Martin Gurdon, Hugh Bradley, James Willoughby, Michael, Matthew Goodman, Joanna Simon,
... and the Will of the People by Jonathan Schell Allen Lane £20 pp448 The artist's models ...
2004 - Gale Group | Sunday Times HA GDA
Mark A. Schell, Maria Karmirantzou, Berend Snel, David Vilanova, Bernard Berger, Gabriella Pessi, Marie-Camille Zwahlen, Frank Desiere, Peer Bork, Michèle Delley, R. David Pridmore, Fabrizio Arigoni,
Bifidobacteria are Gram-positive prokaryotes that naturally colonize the human gastrointestinal tract (GIT) and vagina. Although not numerically dominant in the complex intestinal microflora, they are considered as key commensals that promote a healthy GIT. We determined the 2.26-Mb genome sequence of an infant-derived strain of Bifidobacterium longum , and identified 1,730 possible coding sequences organized in a 60%–GC circular chromosome. Bioinformatic analysis revealed several physiological traits ...
Tópico(s): Genomics and Phylogenetic Studies
2002 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Gráinne Gilmore, Andrew Robson, Sister Helen Prejean, Janice Turner, Victor Fainberg, Johnny Davis, Bel Mooney, Yepoka Yeebo, Amanda Ursell, Simon Barnes, Simon Hills, John Mulvey, Lyudmila Alekseeva, Bernard-Henri LÉvy, Carol Midgley, Melissa Katsoulis, Lucia Van Der Post, Geoff Brown, Elena Kudimova, Lord Judd, Alexei Simonov, Jack Malvern, Dominic Walsh, Aidan White, Elisabeth Rehn, José María Olazábal, Robert Thomson, Helen Monks, Elizabeth Kostova, Jenny MacArthur, Baroness Kennedy, Ben Machell, Sophie Harris, Andrew Ellson Personal Finance Editor, Tina Gaudoin, Steve Hall, Marie Helvin, Helen Rumbelow, Jonathan Sacks, Lucy Sweeney, Tim Teeman, Oliver Kay, Stephen Anderton, Martin Johnson, Ariel Dorfman, Pete Paphides, Jane Fearnley-Whittingstall, Christina Koning, Nicholas Noe, Suzi Godson, Rupert Penry-Jones, Matthew Pryor, Kate Saunders, John Mayer, Rebecca O'connor, Margaret Reynolds, Lord Rea, Nigel Kendall, Jo Darke, Noam Chomsky, Matthew Parris, Mark Bridge, George Caulkin, Lewis Hyde, Russell Jenkins, Caitlin Moran, Iain Finlayson, Peter Riddell, Ben MacIntyre, Mike Atherton, Ben Webster, David Hutcheon, Meg Wolitzer, Baroness Meacher, Anna Shepard, Rick Broadbent Athletics Correspondent, Martin Amis, John Sweeney, Natasha Kandic, Bill Edgar, Michael Evans, Lisa Tuttle, Wangari Maathai, Asma Jahangir, Amit Chaudhurl, Martiin Samuel Chief Football Correspondent, Charles Saumarez Smith, Patrick Rothfuss, Sarah Urwin Jones, Julia Brookes, Severiano Ballesteros, David Cordingly, Clive Davis, Sergey Kovalyov, Richard Hobson One-Day Cricket Correspondent, Elizabeth Judge, Gabrielle Starkey, Patrick Kidd, Graham Stewart, Polly Beard, Elizabeth Frank, Robin Pagnamenta, Caroline Hendrie, Terry Waite, CBE, Harold Pinter, Mitchell Platts, Nancy Durrant, Lord Giddens, Siobhan Kennedy, Francis Elliott, Dan Sabbagh Media Editor, Eve Ensler, Mike Pattenden, Victoria Segal, Tim Reid, Libby Purves, Chris Riley, Heidi Bradner, Phoebe Greenwood, John D. Panitza, Alan Hamilton, Steve Harries, Anne Corbett, Gloria Steinem, Martin Symington, Will Lawrence, Professor Yakin Erturk, Dan Whitcombe, Ed Potton, Ross Clark, Victor Navasky, Mark Henderson Science Editor, John Westerby, Holly Near, Simon de Bruxelles, Magnus Grimond, Gabriel Rozenberg, Anne Nivat, Jeremy Page, Rick Jones, Erica Wagner, Roger Boyes, Marina Litvinenko, Owen Slot Chief Sports Reporter, David Hands Rugby Correspondent, Paul Simons, Steve Jelbert, Dominic Kennedy, Richard Ehrlich, Mel Webb, Dominic Maxwell, David Madel, Elena Bonner, Philip Webster, Stella Rimington, Mark Henderson, Tom McCarthy, Julian Bell, Jody Williams, Ashling O'Connor, Benedict Nightingale, Dr Thomas Stuttaford, Stephen Dalton, Richard Morrison, Simon Herbert, Henry Malt, Philip Oltermann, Olav Bjortomt, Baroness Williams, Peter Ryde, Christopher Irvine, Marianne Gray, Jane MacQuitty, David Hills, Sandra Smith, Sandra Hebron, Robert Lindsay, Peter Kinsley, Jane Knight, Tony Turnbull, Philip Howard, Ben Hoyle Arts Reporter, Rachel Campbell-Johnston, Martin Aston, Kevin Eason, Michael Young, Edward Fuller, Tatiana Yankelevich, Chris Griggs, Deborah Haynes, Tom Bawden, Ruth Gledhill, Gary Jacob, Dubravka Ugresic, Tom Charity, Virginia Nicholson, Daniel Finkelstein, Rosemary Bennett, Dalya Alberge Arts Correspondent, Jo Morris, Irène Némirovsky, Rhys Blakely, Jonathan Schell, Charles Bremner, Ron Lewis, James Mottram, Sir Alexander Macara Chairman, Bincho Yakitori, Aggie MacKenzie, Philip Perry, President Vaclav Havel, Sarah Vine, Mark Atherton, Jane Wheatley, Rick Broadbent, Sally Baker, Jane Knight Deputy Travel Editor, David Baddiel, Rob Wright, Stuart Miles, Edward Gorman Motor Racing Correspondent, Raymond Keene, Luke Leitch, Rebecca O'Connor, Patrick Hosking, Robert Elms, Marcus Leroux, David Mattin, Kenneth Denby, Nick Hasell, Thomasina Miers, Kevin Maher, Tom Dart, Archbishop Desmond Tutu, Nicholas Clee, Joanna Pitman, Robert Crampton, Steve Hawkes, Lord Ahmed, Sir Sigmund Sternberg Honorary Life President, Alan Franks, Sister Marya Grathwohl, Neil Fisher, Michael Austin, Richard Beeston, John Naish, Martin Waller, Chris Ayres, Louise Cohen, Rigoberta MenchÚ Tum, Ellen Khouri, Judith Heywood Deputy Property Editor, Susan Sarandon, Alan Lee Racing Correspondent, Betty Williams, Mariane Pearl, Will Hide, Miles Costello, Giles Smith, Christina Hardyment, Terry Pratchett, Zahid Hussain, John Chave Secretary, The Hon Zbigniew Brzezinski, Brian Selznick, Mark Souster, Clare Lazaro, Gillian Slovo, Simon Cambers, David Chater, Chris Harding, Vladimir Bukovsky, Matthew Michael Carnahan, Michael Cunningham, Andre Glucksmann, Wendy Ide, John Bungey, Lucy Bannerman, Chris Sullivan, Desmond O'malley, Andrew Norfolk, Giles Coren, Vivienne Parry, Sathnam Sanghera, Ray Price Chairman, Ben Webster Transport Correspondent, Mairead Maguire, John H. Hanson, Vinny Lee, Cathy Shelbourne, Sue Townsend, Debra Craine, G. Cummings, Ian Beck, Allan Simmons, Ruth Gledhill Religion Correspondent, Rodney Legg, Richard Ford Home Correspondent, Nick Wyke, Stuart McGurk, Jonathan Richards, Lisa Armstrong Fashion Editor, Derwent May, Kate Muir, Tom Whitwell, David Kitchen, Lisa Armstrong, Tom Baldwin, John Hopkins, Craig Tregurtha, Mark Stratton, Adam Sage, Felipe Fernández-Armesto, Katrina Vanden Heuvel, Esther Chavez, Gordon Ramsay, Roger Phillips, Fran Yeoman, Meglena Kuneva, Jill Sherman, Paul Bentley, Hattie Garlick, Laura Deeley, Damian Whitworth, Ross Leckie, Vanessa Redgrave, James Charles, Peter Dixon, Marek Edelman, Ruth Scurr, Paul Chesters, Philip Webster Political Editor, Lewis Stuart, Caroline McCormick, Ben Hoyle, James Christopher, Robert Cole Personal Investor, Shirin Ebadi, Mike Mitchell, John Sharpe, Alan Jackson, Alex Bellos,
... in the footsteps of Severiano Ballesteros and José Maria Olazábal Where are the young Spaniards? Seve's ...
2007 - Gale Group | TDA
Paul W. Sperduto, Charles Scott, David W. Andrews, M.C. Schell, Maria Werner‐Wasik, William F. Demas, J. K. Ryu, James Fontanesi, Marvin Rotman, Walter J. Curran,
Tópico(s): Advanced Radiotherapy Techniques
2000 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Dae Won Kim, Elaine Tan, Junmin Zhou, Michael J. Schell, María Carmen Riesco Martínez, James Yu, Estrella M. Carballido, Rutika Mehta, Jonathan Strosberg, Iman Imanirad, Richard D. Kim,
MMR proficient (pMMR) colorectal cancer (CRC) is usually unresponsive to immunotherapy. Recent data suggest that ibrutinib may enhance the anti-tumour activity of anti-PD-1 immunotherapy. In this study, we evaluated the safety and efficacy of ibrutinib plus pembrolizumab in refractory metastatic CRC. This was a phase 1/2 study in patients with refractory metastatic pMMR CRC. The primary endpoints for phases 1 and 2 were maximum tolerated dose (MTD) and disease control rate, respectively. The secondary ...
Tópico(s): Lymphoma Diagnosis and Treatment
2021 - Springer Nature | British Journal of Cancer
Jane O. Schell, Maria Da Silva‐Gane, Michael J. Germain,
Elderly patients comprise the fastest growing population initiating dialysis and also experience the worst outcomes, including increased mortality, loss of functional status, and impaired quality of life. Nephrologists are often challenged with how best to engage in dialysis decision-making discussions within this population. Prognostication tools can assist nephrologists in engaging in these discussions, especially in patients for whom survival benefits may be outweighed by the burdens of treatment. ...
Tópico(s): Renal and Vascular Pathologies
2013 - Lippincott Williams & Wilkins | Current Opinion in Nephrology & Hypertension
Paul W. Sperduto, Meihua Wang, H. Ian Robins, Michael C. Schell, Maria Werner‐Wasik, Ritsuko Komaki, Luís Souhami, Mark K. Buyyounouski, Deepak Khuntia, William F. Demas, Sunjay Shah, Lucien Nedzi, Gad Perry, John H. Suh, Minesh P. Mehta,
Background A phase 3 Radiation Therapy Oncology Group (RTOG) study subset analysis demonstrated improved overall survival (OS) with the addition of stereotactic radiosurgery (SRS) to whole brain radiation therapy (WBRT) in non-small cell lung cancer (NSCLC) patients with 1 to 3 brain metastases. Because temozolomide (TMZ) and erlotinib (ETN) cross the blood-brain barrier and have documented activity in NSCLC, a phase 3 study was designed to test whether these drugs would improve the OS associated with WBRT + SRS. ...
Tópico(s): Glioma Diagnosis and Treatment
2013 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
David W. Andrews, Charles Scott, Paul W. Sperduto, Adam E. Flanders, Laurie E. Gaspar, Michael C. Schell, Maria Werner‐Wasik, William F. Demas, Janice Ryu, Jean-Paul Bahary, Luís Souhami, Marvin Rotman, Minesh P. Mehta, Walter J. Curran,
Background Brain metastases occur in up to 40% of all patients with systemic cancer. We aimed to assess whether stereotactic radiosurgery provided any therapeutic benefit in a randomised multi-institutional trial directed by the Radiation Therapy Oncology Group (RTOG). Methods Patients with one to three newly diagnosed brain metastases were randomly allocated either whole brain radiation therapy (WBRT) or WBRT followed by stereotactic radiosurgery boost. Patients were stratified by number of metastases ...
Tópico(s): Meningioma and schwannoma management
2004 - Elsevier BV | The Lancet
Produção Nacional
Revisado por pares
M. Carmen Molina, Rainer Gross, Bernd Schell, Maria Antonia Cuelho Leão, Ulrike Strack, Brunke Brunken,
During the second half of 1986 the health and nutritional status of 254 children aged up to six years was studied, as well as the socio-economic situation of their parents in two favelas (shantytowns) in Belo Horizonte, Brazil. The nutritional status of the children was characterized by stunting (Z-score: 20.1% less than -2) but not by wasting (Z-score: 3.7% less than -2). Consideration was also given to how far stunting was caused by high morbidity such as acute respiratory infections (point prevalence: ...
Tópico(s): Child Nutrition and Water Access
1989 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Terry L. Schell, Maria Orlando, Andrew R. Morral,
To document the prospective, reciprocal relationships among substance use problems, utilization of drug treatment, and predisposing beliefs thought to increase treatment utilization.Persistent Effects of Treatment Study-Adolescent (PETS-A), conducted by the Center on Substance Abuse Treatment. This was a longitudinal study of youths originally participating in one of two CSAT studies; one sample included 476 youths receiving residential drug treatment, and the other included 519 youths receiving ...
Tópico(s): Advanced Causal Inference Techniques
2005 - Wiley | Health Services Research
Henry Otgaar, Jennifer Maria Schell‐Leugers, Mark L. Howe, Alejandra de la Fuente Vilar, Sanne T. L. Houben, Harald Merckelbach,
Abstract Expert witnesses and scholars sometimes disagree on whether suggestibility and compliance are related to people's tendency to falsely confess. Hence, the principal aim of this review was to amass the available evidence on the link between suggestibility and compliance and false confessions. We reviewed experimental data in which false confessions were experimentally evoked and suggestibility and compliance were measured. Furthermore, we reviewed field data of potential false confessions ...
Tópico(s): Adversarial Robustness in Machine Learning
2021 - Wiley | Applied Cognitive Psychology
Melanie Sauerland, Jennifer Maria Schell‐Leugers, Jorg Collaris, Nils Karl Reimer, Marian Schneider, Harald Merckelbach,
Across two experiments, we studied a phenomenon akin to choice blindness in the context of participants' accounts of their own history of norm‐violating behaviors. In Experiment 1, N = 67 participants filled in an 18‐item questionnaire about their history of norm‐violating behaviors (QHNVB). Subsequently, they were questioned about four of their answers, two of which had covertly been manipulated by the experimenter. Of the 134 manipulations, 20 (14.9%) remained undetected concurrently and 13 were accepted ...
Tópico(s): Social and Intergroup Psychology
2013 - Wiley | Behavioral Sciences & the Law
Jennifer V. Hall, Maria Schell, Sophie Dessus-Babus, Cheryl G. Moore, Judy D. Whittimore, Melanie Sal, Brian D. Dill, Priscilla B. Wyrick,
The oestrogen receptor (ER) α-β+ HEC-1B and the ERα+β+ Ishikawa (IK) cell lines were investigated to dissect the effects of oestrogen exposure on several parameters of Chlamydia trachomatis infection. Antibody blockage of ERα or ERβ alone or simultaneously significantly decreased C. trachomatis infectivity (45-68%). Addition of the ERβ antagonist, tamoxifen, to IK or HEC-1B prior to or after chlamydial infection caused a 30-90% decrease in infectivity, the latter due to disrupted eukaryotic organelles. ...
Tópico(s): Reproductive Physiology in Livestock
2011 - Wiley | Cellular Microbiology
Jeffrey D. Miller, Melanie Sal, Maria Schell, Judy D. Whittimore, Jane E. Raulston,
Chlamydia trachomatis is a Gram-negative obligate intracellular bacterium that is the causative agent of common sexually transmitted diseases and the leading cause of preventable blindness worldwide. It has been observed that YtgA (CT067) is very immunogenic in patients with chlamydial genital infections. Homology analyses suggested that YtgA is a soluble periplasmic protein and a component of an ATP-binding cassette (ABC) transport system for metals such as iron. Since little is known about iron ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2009 - Microbiology Society | Microbiology
Carlos Bantar, Celia María Schell, Graciela Posse, Adriana S. Limansky, Viviana Ballerini, Liliana Mobilia,
To assess potential alternative options for the treatment of infections caused by Acinetobacter baumannii, we performed time-kill studies of doxycycline and tigecycline using several isolates recovered from patients residing in 10 different cities in Argentina. Imipenem and sulbactam were also included for comparison purposes. Eleven isolates representing 5 distinctive clones, or isolates with different susceptibility patterns within the same clone, were selected. Tubes containing cation-supplemented ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2008 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Jane E. Raulston, Jeffrey D. Miller, Caroyn H. Davis, Maria Schell, Amy Baldwin, Kaethe P. Ferguson, Heather Lane,
Chlamydia trachomatis is an important cause of immune-mediated damage to the reproductive tract of infected patients. Certain chlamydial antigens and host genetic factors have been identified as contributing to immunopathological events, but a comprehensive understanding of specific components involved in destructive vs. protective immune responses to chlamydial infections is far from clear. In this study, it is shown that C. trachomatis-infected patients generate antibodies against an iron-responsive ...
Tópico(s): Gut microbiota and health
2007 - Oxford University Press | FEMS Immunology & Medical Microbiology
Jonathan S. Wall, Vibha Gupta, Matthew D. Wilkerson, Maria Schell, Remy Loris, Paul D. Adams, Alan Solomon, Fred J. Stevens, Chris Dealwis,
Abstract Primary (AL) amyloidosis results from the pathologic deposition of monoclonal light chains as amyloid fibrils. Studies of recombinant‐derived variable region (V L ) fragments of these proteins have shown an inverse relationship between thermodynamic stability and fibrillogenic potential. Further, ionic interactions within the V L domain were predicted to influence the kinetics of light chain fibrillogenicity, as evidenced from our analyses of a relatively stable V λ 6 protein (Jto) with a long ...
Tópico(s): Protein Structure and Dynamics
2004 - Wiley | Journal of Molecular Recognition
Rudi Hrncic, Jonathan S. Wall, D Wolfenbarger, Charles L. Murphy, Maria Schell, Deborah Weiss, Alan Solomon,
Primary light-chain-associated (AL) amyloidosis is characterized by the deposition in tissue of monoclonal light chains as fibrils. With rare exception, this process is seemingly irreversible and results in progressive organ dysfunction and eventually death. To determine whether immune factors can effect amyloid removal, we developed an experimental model in which mice were injected with amyloid proteins extracted from the spleens or livers of patients with AL amyloidosis. Notably, the resultant ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2000 - Elsevier BV | American Journal Of Pathology
Kai Tang, S. L. Allman, C. H. Chen, Li-Pin Chang, Maria Schell,
Abstract Matrix‐assisted laser desorption/ionization, by a time‐of‐flight mass spectrometer, has been successfully used for detection of restriction enzyme‐digested DNA. However, the oligonucleotide segments detected correspond to the molecular weights of single strands.
Tópico(s): Analytical Chemistry and Chromatography
1994 - Wiley | Rapid Communications in Mass Spectrometry
Ch'ang Lan-Yang, Yen Chin-Ping, Linda Besl, Maria Schell, Alan Solomon,
We have isolated from a human genomic library a potentially functional and distinctive germline gene, designated IGLV6S1, that encodes for light chains of the V lambda VI subgroup. An identical germline gene was cloned from fibroblasts obtained from a patient with light-chain-associated amyloidosis (AL amyloidosis) whose serum and urine contained, respectively, a monoclonal IgG lambda VI protein and a lambda VI Bence Jones protein. Isolation and characterization of cDNA cloned from the patient's ...
Tópico(s): T-cell and B-cell Immunology
1994 - Elsevier BV | Molecular Immunology
Zsófia Bánfalvi, A J Nieuwkoop, Maria Schell, Linda Besl, Gary Stacey,
Tópico(s): Plant responses to water stress
1988 - Springer Science+Business Media | MGG Molecular & General Genetics
A J Nieuwkoop, Zsófia Bánfalvi, N. Deshmane, David Gerhold, Maria Schell, Karl Sirotkin, Gary Stacey,
By using cloned Rhizobium meliloti, Rhizobium leguminosarum, and Rhizobium sp. strain MPIK3030 nodulation (nod) genes as hybridization probes, homologous regions were detected in the slow-growing soybean symbiont Bradyrhizobium japonicum USDA 110. These regions were found to cluster within a 25-kilobase (kb) region. Specific nod probes from R. meliloti were used to identify nodA-, nodB-, nodC-, and nodD-like sequences clustered on two adjacent HindIII restriction fragments of 3.9 and 5.6 kb. A 785- ...
Tópico(s): Plant nutrient uptake and metabolism
1987 - American Society for Microbiology | Journal of Bacteriology
Paul Russell, Maria Schell, Kristin K. Nelson, Larry J. Halverson, Karl Sirotkin, Gary Stacey,
The DNA region encoding early nodulation functions of Bradyrhizobium japonicum 3I1b110 (I110) was isolated by its homology to the functionally similar region from Rhizobium meliloti. Isolation of a number of overlapping recombinant clones from this region allowed the construction of a restriction map of the region. The identified nodulation region of B. japonicum shows homology exclusively to those regions of R. meliloti and Rhizobium leguminosarum DNA known to encode early nodulation functions. ...
Tópico(s): Legume Nitrogen Fixing Symbiosis
1985 - American Society for Microbiology | Journal of Bacteriology
Jonathan S. Wall, Stephen J. Kennel, Michael J. Paulus, Shaun S. Gleason, Jens Gregor, Justin S. Baba, Maria Schell, Tina Richey, Brian O’Nuallain, Robert L. Donnell, Philip N. Hawkins, Deborah Weiss, Alan Solomon,
The mouse model of experimentally induced systemic AA amyloidosis is long established, well validated, and closely analogous to the human form of this disease. However, the induction of amyloid by experimental inflammation is unpredictable, inconsistent, and difficult to modulate. We have previously shown that murine AA amyloid deposits can be imaged using iodine-123 labeled SAP scintigraphy and report here substantial refinements in both the imaging technology and the mouse model itself. In this ...
Tópico(s): Medical Imaging Techniques and Applications
2005 - Taylor & Francis | Amyloid
Daniel Coriu, Kristal Weaver, Maria Schell, Manfred Eulitz, Charles L. Murphy, Deborah Weiss, Alan Solomon,
Abstract The biosynthesis of aberrant immunoglobulin polypeptides by monoclonal plasma cells has been implicated in the pathogenesis of nonsecretory myeloma. Our studies of a patient with this disorder indeed have demonstrated the presence of abnormal κ light chains that resulted from a frameshift mutation in nucleotides encoding the constant region of the molecule. As a consequence of a 2-base deletion in codon 187 and loss of the normal stop codon, this portion of the κ chain was composed of 128 ...
Tópico(s): Multiple Myeloma Research and Treatments
2004 - Elsevier BV | Blood
Alan Solomon, Deborah Weiss, Maria Schell, Rudi Hrncic, Charles L. Murphy, Jonathan S. Wall, Μ. D. McGavin, Hong Jun Pan, George W. Kabalka, Michael J. Paulus,
AA amyloidosis can be induced in mice experimentally through injection of certain chemical or biological compounds. However, the usefulness of this approach is limited by its dependence on exogenous inflammatory agents that stimulate cytokines to increase the synthesis of precursor serum amyloid A (SAA) protein and the transitory nature of the pathological fibrillar deposits. We now report that transgenic mice carrying the human interleukin 6 gene under the control of the metallothionein-I promoter ...
Tópico(s): Prion Diseases and Protein Misfolding
1999 - Elsevier BV | American Journal Of Pathology
Jonathan S. Wall, Maria Schell, Charles L. Murphy, Rudi Hrncic, Fred J. Stevens, Alan Solomon,
Certain types of human light chains have the propensity to deposit pathologically as amyloid fibrils as evidenced by the preferential association of monoclonal λ6 proteins with AL amyloidosis. However, the molecular features that render such proteins amyloidogenic have not been elucidated. Based upon the demonstrated relationship between the thermodynamic stability of light chains and their propensity to aggregate in vitro, we have initiated studies where the thermodynamic properties and fibrillogenic ...
Tópico(s): Prion Diseases and Protein Misfolding
1999 - American Chemical Society | Biochemistry
Alan Solomon, Deborah Weiss, Charles L. Murphy, Rudi Hrncic, Jonathan S. Wall, Maria Schell,
Light chain-associated amyloidosis is characterized by the deposition as fibrils of monoclonal light chain-related components consisting predominately of the variable domain (VL) or the VL plus up to approximately 60 residues of the constant domain (CL). Here, we describe a patient (designated BIF) with light chain-associated amyloidosis and kappa Bence Jones proteinuria in whom, notably, >80% of the amyloid deposits were comprised of CL-related material. The extracted amyloid protein consisted of 99 ...
Tópico(s): Drug Transport and Resistance Mechanisms
1998 - National Academy of Sciences | Proceedings of the National Academy of Sciences