Produção Nacional
Revisado por pares
Vania Dos Santos, Karoline Leite, Mariana Da Costa Siqueira, Luís Octávio Regasini, Isabel Martínez, C Ribeiro Nogueira, Mariana K. Galuppo, Beatriz Simonsen Stolf, Ana Maria Soares Pereira, Regina Maria Barretto Cicarelli, Maysa Furlan, Márcia A. S. Graminha,
The present study describes the leishmanicidal and trypanocidal activities of two quinonemethide triterpenes, maytenin (1) and pristimerin (2), isolated from Maytenus ilicifolia root barks (Celastraceae). The compounds were effective against the Trypanosomatidae Leishmania amazonensis and Leishmania chagasi and Trypanosoma cruzi, etiologic agents of leishmaniasis and Chagas’ disease, respectively. The quinonemethide triterpenes 1 and 2 exhibited a marked in vitro leishmanicidal activity against promastigotes ...
Tópico(s): Phytochemical compounds biological activities
2013 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Lívia Greghi Espanha, Flávia Aparecida Resende, José de Sousa Lima Neto, Paula Karina Boldrin, Catarine Haidê Nogueira, Mariana S. de Camargo, Rone Aparecido De Grandis, Lourdes Campaner dos Santos, Wagner Vilegas, Eliana Aparecida Varanda,
In various regions of Brazil, several species of the genus Byrsonima (Malpighiaceae) are widely used to treat gastrointestinal complications. This genus has about 150 species of shrubs and trees distributed over the entire Neotropical region. Various biological activities have been identified in these plants, especially antioxidant, antimicrobial and topical and systemic anti-inflammatory activities. The aim of this study was to investigate the mutagenicity and antimutagenicity of hydroalcoholic ...
Tópico(s): Phytochemistry and biological activity of medicinal plants
2014 - BioMed Central | BMC Complementary and Alternative Medicine
Produção Nacional
Revisado por pares
Mônica Paschoal Nogueira, Mariana Farcetta, Mark Fox, Katy Miller, Tatiana da Silva Pereira, José A. Morcuende,
This study aimed to analyze the perceptions of parents of children with clubfoot regarding the Ponseti method of treatment, and identify aspects of treatment that families found most difficult. Thirty families of children with clubfoot were treated with the Ponseti method over a 4-year period, and questionnaires were distributed at the conclusion of treatment. The most difficult components of treatment were identified. However, these challenges did not impact treatment outcome negatively. We hypothesize ...
Tópico(s): Spinal Dysraphism and Malformations
2013 - Wolters Kluwer | Journal of Pediatric Orthopaedics B
Produção Nacional
Revisado por pares
Thaïs Florence D. Nogueira, Mariana Porto Zambon,
OBJECTIVE To analyze the reasons for non-adherence to follow-up at a specialized outpatient clinic for obese children and adolescents. METHODS Descriptive study of 41 patients, including information from medical records and phone recorded questionnaires which included two open questions and eight closed ones: reason for abandonment, financial and structural difficulties (distance and transport costs), relationship with professionals, obesity evolution, treatment continuity, knowledge of difficulties ...
Tópico(s): Eating Disorders and Behaviors
2013 - Elsevier BV | Revista Paulista de Pediatria
Produção Nacional
Revisado por pares
Daniel Molins-Delgado, Ramón Muñoz, Sylvia Nogueira, Mariana B. Alonso, João Paulo Machado Torres, Olaf Malm, Roberta Lourênço Ziolli, Rachel Ann Hauser‐Davis, Ethel Eljarrat, Damià Barceló, M. Silvia Díaz˗Cruz,
Tópico(s): Antioxidant Activity and Oxidative Stress
2017 - Elsevier BV | The Science of The Total Environment
Juliane Cristina Ciccone-Nogueira, Mariana Cristina Borsatto, Wanessa Christine de Souza-Zaron, Renata Pereira Ramos, Regina Guenka Palma‐Dibb,
The purpose of this study was to assess the microhardness of posterior composite resins at different depths varying the post-irradiation time.For each composite resin [Solitaire 2 (SO) - Heraus Kulzer, P60 (P) - 3M, Prodigy Condesable (PC) - Kerr, Surefil (S) - Dentsply and Alert (A) - Pentron], 6 specimens (3 mm in diameter; 4 mm high) were prepared using a black polyurethane cylindrical matrix. The resins were inserted in a bulk increment and light cured for 40 seconds. Microhardness was analyzed at different ...
Tópico(s): Endodontics and Root Canal Treatments
2007 - UNIVERSIDADE DE SÃO PAULO | Journal of Applied Oral Science
Produção Nacional
Grínia M. Nogueira, Mariana Agostini de Moraes, Andrea C.D. Rodas, Olga Z. Higa, Marisa Masumi Beppu,
Silk fibroin (SF) hydrogels were obtained from the dialysis of a SF metastable solution. Temperature and calcium concentration in SF solution/hydrogel were measured, as critical variables for SF gelation phenomenon. Gelation time of SF solution was increased by decreasing the dialysis temperature, whereas the residual calcium concentration was higher when higher dialysis temperatures were applied. Hydrogels obtained at 20 °C were characterized after freeze-drying. SEM micrographs showed porous structures, ...
Tópico(s): Biochemical and Structural Characterization
2011 - Elsevier BV | Materials Science and Engineering C
Produção Nacional
Revisado por pares
Maira Eiko Ikuma Nogueira, Mariana Henrique Passoni, Fabiana Izilda Biso, Maria do Carmo Longo, Cássia Regina Cardoso, Lourdes Campaner dos Santos, Eliana Aparecida Varanda,
Melampodium divaricatum is a member of the Asteraceae and in Brazil is known as false-calendula, its flowers being used in anti-inflammatory preparations, substituting the true calendula or marigold (Calendula officinalis L.). The flower extract was investigated for mutagenic and antimutagenic effect in the Salmonella/microsome assay. The tested extract was not mutagenic in the strains TA100, TA98, TA97a and TA102 and decreased the mutagenicity of aflatoxin B1, benzo(a)pyrene and daunomycin. Chlorophyll ...
Tópico(s): Genetically Modified Organisms Research
2005 - Elsevier BV | Toxicology in Vitro
Produção Nacional
Revisado por pares
Karoline Maria Vieira Nogueira, Mariana do Nascimento Costa, Renato Graciano de Paula, Flávia Costa Mendonça-Natividade, Rafael Ricci-Azevedo, Roberto Nascimento Silva,
The signaling second messenger cyclic AMP (cAMP) regulates many aspects of cellular function in all organisms. Previous studies have suggested a role for cAMP in the regulation of gene expression of cellulolytic enzymes in Trichoderma reesei (anamorph of Hypocrea jecorina). The effects of cAMP in T. reesei were analyzed through both activity and expression of cellulase, intracellular cAMP level measurement, western blotting, indirect immunofluorescence and confocal microscopy. To elucidate the involvement ...
Tópico(s): Fungal and yeast genetics research
2015 - BioMed Central | BMC Microbiology
Produção Nacional
Revisado por pares
Fernando Shintate Galindo, Marcelo Carvalho Minhoto Teixeira Filho, Salatiér Buzetti, José Mateus Kondo Santini, Cleiton José Alves, Lais Meneghini Nogueira, Mariana Gaioto Ziolkowski Ludkiewicz, Marcelo Andreotti, João Leonardo Miranda Bellotte,
The biological nitrogen fixation (BNF) process in grasses is caused by diazotrophic bacteria, particularly Azospirillum brasilense.However, studies are lacking on BNF efficiency to define how much mineral nitrogen (N) can be applied to achieve more sustainable high yields.Furthermore, there should be an analysis of whether urea with the urease enzyme inhibitor NBPT is less harmful, benefiting BNF in grasses.The objective of this study was to evaluate the effect of N sources and N rates associated ...
Tópico(s): Growth and nutrition in plants
2016 - Sociedade Brasileira de Ciência do Solo | Revista Brasileira de Ciência do Solo
Produção Nacional
Revisado por pares
Letícia E. Sewaybricker, Ellen A. Schur, Susan J. Melhorn, Brunno Machado de Campos, Mary K. Askren, Guilherme Nogueira, Mariana Porto Zambon, Maria Ângela R. G. M. Antônio, Fernando Cendes, Lı́cio A. Velloso, Gil Guerra‐Júnior,
Summary Objective In adults, hypothalamic gliosis has been documented using quantitative T2 neuroimaging, whereas functional magnetic resonance imaging (fMRI) has shown a defective hypothalamic response to nutrients. No studies have yet evaluated these hypothalamic abnormalities in children with obesity. Methods Children with obesity and lean controls underwent quantitative MRI measuring T2 relaxation time, along with continuous hypothalamic fMRI acquisition to evaluate early response to glucose ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2018 - Wiley | Pediatric Obesity
Produção Nacional
Revisado por pares
Lorena Salim Sousa, T. S. Carvalho, Flávia Aparecida Nogueira, Mariana Masseo Saldanha, Diêgo Pereira Vaz, Antônio Gilberto Bertechini, N.C. Baião, L.J.C. Lara,
The objective of this study was to ascertain the influence of different dietary fiber sources and the usage of xylanase on diet of commercial layers and their influence on productive performance, egg quality, and digestive organ biometry. A total of 864 Lohmann® White hens was fed diets with three different fiber sources (wheat bran, soybean hull, or coffee husk) with or without xylanase inclusion (concentration of 160,000 BXU/g) in a 3×2 factorial arrangement, with six replicates of 24 birds each, ...
Tópico(s): Aquaculture Nutrition and Growth
2019 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Produção Nacional
Revisado por pares
Talita Braga de Brito Nogueira, Mariana Simões Larraz Ferreira, Ana Elizabeth Cavalcante Fai,
Fruit and vegetable residues have high levels of nutrients and phytochemicals such as in edible parts. However, they are not exploited and disposed properly. Advanced methodologies used to extract and characterize bioactive compounds, such as chromatography and mass spectrometry have been studied. Obtaining new materials in food and pharmaceutical industries have also been outlined in these works. This review analyzed a number of studies on sustainable applications utilizing fruit and vegetable ...
Tópico(s): Proteins in Food Systems
2020 - Taylor & Francis | Food Reviews International
Francisca Dias, Ana Luísa Teixeira, Inês Nogueira, Mariana Morais, Joana Maia, Cristian Bodo, M. Ferreira, Isabel Vieira, José Silva, João Lobo, José Pedro Sequeira, Joaquina Maurício, Jorge Oliveira, Carlos Palmeira, Gabriela Martins, Klaas Kok, Bruno Costa‐Silva, Rui Medeiros,
The tumor microenvironment has gained a lot of attention from the scientific community since it has a proven impact in the development of tumor progression and metastasis. Extracellular vesicles (EVs) are now considered one of the key players of tumor microenvironment modulation. Clear cell renal cell carcinoma (ccRCC) is the most lethal urological neoplasia and presents a high metastatic potential, which reinforces the need for the development of more effective predictive biomarkers. Our goal was ...
Tópico(s): Cardiovascular Disease and Adiposity
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Francisca Dias, Ana Luísa Teixeira, Inês Nogueira, Mariana Morais, Joana Maia, Cristian Bodo, M. Ferreira, Alexandra Silva, Manuela Vilhena, João Lobo, José Pedro Sequeira, Joaquina Maurício, Jorge Oliveira, Klaas Kok, Bruno Costa‐Silva, Rui Medeiros,
Clear cell renal cell carcinoma (ccRCC) is the most aggressive subtype of kidney cancer and up to 40% of patients submitted to surgery with a curative intent will relapse. Thus, the aim of this study was to analyze the applicability of an Extracellular vesicle (EV) derived miRNA profile as potential prognosis biomarkers in ccRCC patients. We analyzed a nine-miRNA profile in plasma EVs from 32 ccRCC patients with localized disease (before and after surgery) and in 37 patients with metastatic disease. ...
Tópico(s): Renal and related cancers
2020 - Multidisciplinary Digital Publishing Institute | Cancers
Produção Nacional
Revisado por pares
Camila Lorenz, Márcia C. Castro, Patricia Michele Pereira Trindade, Maurício Lacerda Nogueira, Mariana de Oliveira Lage, José Alberto Quintanilha, Maisa Carla Pereira Parra, Margareth Regina Dibo, Eliane Aparecida Fávaro, Marluci Monteiro Guirado, Francisco Chiaravalloti Neto,
Abstract Identifying Aedes aegypti breeding hotspots in urban areas is crucial for the design of effective vector control strategies. Remote sensing techniques offer valuable tools for mapping habitat suitability. In this study, we evaluated the association between urban landscape, thermal features, and mosquito infestations. Entomological surveys were conducted between 2016 and 2019 in Vila Toninho, a neighborhood of São José do Rio Preto, São Paulo, Brazil, in which the numbers of adult female ...
Tópico(s): Climate Change and Health Impacts
2020 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Aroldo dos Santos Aguiar, Helen Cristina Nogueira, Mariana Romano de Lira, Gabriela Zuelli Martins Silva, Thaís Cristina Chaves,
Introduction: Several patient-reported outcome measurements (PROMs) are available in the literature to support the evaluation and diagnosis of temporomandibular disorders and headaches. However, clinicians and researchers usually complain that they had no education on PROMs and low overall knowledge about PROMs. Objective: This study aimed to summarize, describing the measurement properties and clinical applicability of the main condition-specific PROMs available in the literature to the assessment ...
Tópico(s): Trigeminal Neuralgia and Treatments
2021 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Produção Nacional
Revisado por pares
Marjorie Caroline Liberato Cavalcanti Freire, G.D. Noske, Natália Vitória Bitencourt, Paulo R. S. Sanches, Norival A. Santos‐Filho, Victor O. Gawriljuk, Eduardo Pereira de Souza, Victor H. R. Nogueira, Mariana Ortiz de Godoy, A.M. Nakamura, R.S. Fernandes, André S. Godoy, María A. Juliano, Bianca de Miranda Peres, Cecília Gomes Barbosa, Carolina Borsoi Moraes, Lúcio H. Freitas-Júnior, Eduardo Maffud Cilli, Rafael V. C. Guido, Glaucius Oliva,
The COVID-19 outbreak has rapidly spread on a global scale, affecting the economy and public health systems throughout the world. In recent years, peptide-based therapeutics have been widely studied and developed to treat infectious diseases, including viral infections. Herein, the antiviral effects of the lysine linked dimer des-Cys11, Lys12,Lys13-(pBthTX-I)2K ((pBthTX-I)2K)) and derivatives against SARS-CoV-2 are reported. The lead peptide (pBthTX-I)2K and derivatives showed attractive inhibitory ...
Tópico(s): vaccines and immunoinformatics approaches
2021 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Lívia Alves Amaral Santos, Talles Bazeia Lima, Laís Augusti, L. Franzoni, Fábio da Silva Yamashiro, Fernanda Bolfi, Vânia dos Santos Nunes Nogueira, Mariana de Souza Dorna, Cássio Vieira de Oliveira, Carlos Antônio Caramori, Giovanni Faria Silva, Fernando Gomes Romeiro,
Osteoporosis is well recognized as a cirrhosis complication; however, most studies assessing this condition included only patients on liver transplantation lists with an elevated rate of bone diseases. While general population studies show that handgrip strength is clearly associated with bone mineral density, until now this tool has not been applied to patients with cirrhosis in relation to their bone condition. This study aimed to evaluate whether handgrip strength, bone, and liver tests may be ...
Tópico(s): Bone and Joint Diseases
2015 - Wiley | Journal of Gastroenterology and Hepatology
Produção Nacional
Revisado por pares
Francisco de Carvalho Nogueira, Mariana Alves Pagotto, Fidel A. Roig, Cláudio Sérgio Lisi, Adauto de Souza Ribeiro,
This paper aims to provide evidences of the influence of physical atmospheric parameters on the growth of the endemic tree Schinopsis brasiliensis, and their consequent teleconnection with large-scale modes of climate variability affecting rainfall in semi-arid region of the Brazilian Northeast. The Brazilian Northeast is a region of low rainfall and high temperatures and evaporation. The surface temperature of the Atlantic Ocean (STA) modulates the rains in the Northeast in association with El Niño ...
Tópico(s): Plant Diversity and Evolution
2017 - Springer Science+Business Media | Trees
Ana Silva, Paulo Nogueira, Mariana Verdelho Machado,
NAFLD can occur after liver transplantation (LT), as recurrence or de novo hepatic steatosis (HS). We aimed to evaluate the literature on prevalence, risk factors, and prognosis of post-LT HS. Systematic review with meta-analysis through a search on: PUBMED, Scopus, and Web-of-Science, from inception until the September 30, 2021. Forty studies were included, representing 6979 patients. The post-LT HS prevalence was 39.76% (95% CI, 34.06–45.46), with a rising kinetics (11.06% increase per decade, p =0. ...
Tópico(s): Liver Diseases and Immunity
2023 - Lippincott Williams & Wilkins | Liver Transplantation
Produção Nacional
Revisado por pares
Monize Caiado Decarli, Mateus Vidigal de Castro, Júlia A. Nogueira, Mariana Harue Taniguchi Nagahara, Cecília Buzatto Westin, Alexandre Leite Rodrigues de Oliveira, Jorge Vicente L. da Silva, Lorenzo Moroni, Carlos Mota, Ângela Maria Moraes,
Three-dimensional cellular aggregates can mimic the natural microenvironment of tissues and organs and obtaining them through controlled and reproducible processes is mandatory for scaling up and implementing drug cytotoxicity and efficacy tests, as well as tissue engineering protocols. The purpose of this work was to develop and evaluate the performance of a device with two different geometries fabricated by additive manufacturing. The methodology was based on casting a microwell array insert using ...
Tópico(s): Microfluidic and Bio-sensing Technologies
2022 - Elsevier BV | Biomaterials Advances
Produção Nacional
Revisado por pares
Maria Lourdes Barjas‐Castro, Rodrigo Nogueira Angerami, Mariana Sequetin Cunha, Akemi Suzuki, Juliana Silva Nogueira, Iray Maria Rocco, Adriana Yurika Maeda, Fernanda Gisele Silva Vasami, Gizelda Katz, I.F.S.F. Boin, R.S.B. Stucchi, Mariângela Ribeiro Resende, Danillo Lucas Alves Espósito, Renato Pereira de Souza, Benedito Antônio Lopes da Fonseca, Marcelo Addas‐Carvalho,
BACKGROUND Zika virus (ZIKV) is an emerging arthropod‐borne flavivirus transmitted by Aedes mosquitoes. Recent commentaries regarding ZIKV routes of transmission describe a potential transmission by transfusion. Herein, we report a probable case of transfusion‐transmitted ZIKV infection through a platelet transfusion that was detected from postdonation information. CASE REPORT A blood donor made a voluntary telephone report to the blood donor facility 3 days after donation and informed the facility ...
Tópico(s): Malaria Research and Control
2016 - Wiley | Transfusion
Produção Nacional
Revisado por pares
Francisco de Carvalho Nogueira, Mariana Alves Pagotto, José Roberto Vieira Aragão, Fidel A. Roig, Adauto de Souza Ribeiro, Cláudio Sérgio Lisi,
Tópico(s): Forest ecology and management
2019 - Springer Science+Business Media | Biological Invasions
Arthur Galvão Rodrigues Costa, Bianca Dore Soares Guedes, Maria Motta Nogueira, Mariana Pereira Augusto Maciel,
Introdução: A adolescência e juventude é uma época marcada por mudanças físicas, biológicas e psicossociais, as quais implicam na necessidade de vivenciar novas experiências e aprendizados, analisando tópicos a respeito da saúde, sexualidade e questões sociais. As Diretrizes de Atenção Integral de Saúde de Adolescentes e Jovens visam o fortalecimento da prevenção e promoção da saúde para esse grupo prioritário, por meio da reorientação dos serviços de saúde a fim de favorecer a eficácia das respostas ...
Tópico(s): Healthcare Regulation
2021 - Brazilian Journal of Development | Brazilian Journal of Health Review
Produção Nacional
Revisado por pares
Glória M. S. A. Tedrus, Elizardo Nogueira, Mariana Almeida Vidal,
Purpose To assess the clinical-EEG aspects, characterization of subtypes, relationships with prognostic scales and the occurrence of death in elderly patients in the acute phase of nonconvulsive status epilepticus (NCSE). Methodology Clinical variables, EEG data, Status epilepticus severity score (STESS), and the Epidemiology-based mortality score in status epilepticus (EMSE) were related to the death of 96 patients who were over 60 years old, with NCSE. Results NCSE with coma was observed in 31 patients ( ...
Tópico(s): Functional Brain Connectivity Studies
2021 - Elsevier BV | Seizure
Produção Nacional
Revisado por pares
Fábio Alves Teixeira, Mariana Ramos Queiroz, Patrícia M Oba, Rodrigo Fernando Gomes Olivindo, Mariane Ceschin Ernandes, Caio Nogueira Duarte, Mariana Fragoso Rentas, Márcio Antônio Brunetto,
The knowledge of how owners view the body condition of their animals is an important factor for the success of the prevention/treatment of obesity and the engagement/adherence to nutritional interventions, which are fundamental to improve the animal prognosis. For this reason, the objective of this study was to evaluate the perception of the owners regarding the body condition score of their animals, compare the perception between cat vs. dog owners, and owners from the countryside vs. metropolitan ...
Tópico(s): Veterinary Equine Medical Research
2020 - BioMed Central | BMC Veterinary Research
Maria Alice Nogueira, Mariana Gadoni Canaan,
Este trabalho examina o impacto da iniciação científica sobre o percurso acadêmico do estudante. Verificou-se que os bolsistas de iniciação científica tiveram acesso, tanto ao mestrado quanto ao doutorado, em uma proporção bem superior aos não-bolsistas, e que essa discrepância esteve presente em todas as áreas do conhecimento. Diferenças notáveis também foram constatadas na idade de ingresso na pós-graduação stricto sensu e no intervalo de tempo despendido entre a conclusão do nível anterior (graduação ...
Tópico(s): Education and Public Policy
2009 - FUNDAÇÃO UNIVERSIDADE FEDERAL DE SERGIPE | Revista TOMO
Produção Nacional
Revisado por pares
Pedro Thalles Bernardo de Carvalho Nogueira, Mariana Maria Castro Jatobá Remigio, Andreza Maria Correia de Queiroz, Andréia Aparecida da Silva, José Rodrigues Laureano Filho,
Cryosurgery is a treatment modality consisting in the destruction of tissue by the application of extremely low temperatures. This causes irreversible damage to cellular metabolism, leading to tissue destruction within minutes, a mechanism that may be beneficial when used in diseased tissues. Because cryosurgery is effective, simple, and easy to perform, it has been used in the treatment of lesions in both medical and dental fields. This technique provides many advantages, such as easy operation, ...
Tópico(s): Oral and Maxillofacial Pathology
2017 - Hindawi Publishing Corporation | Case Reports in Otolaryngology
Produção Nacional
Revisado por pares
Francisco Humberto Nociti, Getúlio da Rocha Nogueira Filho, Mariana T. Primo, Maria Ângela Naval Machado, Vinícius Augusto Tramontina, Silvana P. Barros, Enílson Antônio Sallum,
The present study investigated the possible influence of nicotine on the bone loss rate in the furcation region due to ligature-induced periodontitis in rats.Twenty adult male Wistar rats were included. After anesthesia, the tooth was randomly assigned to receive the cotton ligature in the sulcular area, while the contralateral tooth was left unligated. The animals were randomly assigned to one of the following treatments, including daily intraperitoneal injections: group A, 2 microl/g body weight ...
Tópico(s): Dental Anxiety and Anesthesia Techniques
2000 - Wiley | Journal of Periodontology