Marimar Sáez‐de‐Ocariz, Eduardo López‐Corella, Carola Durán‐McKinster, Luz Orozco‐Covarrubias, Ramón Ruiz‐Maldonado,
... PRECEDING THE DEVELOPMENT OF INSULIN-DEPENDENT DIABETES MELLITUS MARIMAR SAEZ-DE-OCARIZ M.D., MARIMAR SAEZ-DE-OCARIZ M.D. Mexico City, MexicoSearch ... City, MexicoSearch for more papers by this author MARIMAR SAEZ-DE-OCARIZ M.D., MARIMAR SAEZ-DE-OCARIZ M.D. Mexico City, MexicoSearch ...
Tópico(s): Pancreatic function and diabetes
2006 - Wiley | Pediatric Dermatology
Marimar Sáez‐de‐Ocariz, Cristina Sosa‐de‐Martínez, Carola Durán‐McKinster, Luz Orozco‐Covarrubias, Carolina Palacios‐López, Ramón Ruiz‐Maldonado,
... in private vs. public practices of Mexican dermatologists Marimar Saez-de-Ocariz MD, Marimar Saez-de-Ocariz MD From the Dermatology and ... Mexico CitySearch for more papers by this author Marimar Saez-de-Ocariz MD, Marimar Saez-de-Ocariz MD From the Dermatology and ...
Tópico(s): Immunotherapy and Immune Responses
2008 - Wiley | International Journal of Dermatology
Maria Teresa García‐Romero, Carola Durán‐McKinster, Marimar Sáez de Ocariz, Daniel Carrasco‐Daza, Carolina Palacios‐López, Luz Orozco‐Covarrubias, Ramón Ruiz‐Maldonado,
... papers by this authorMarimar Sáez de Ocariz MD, Marimar Sáez de Ocariz MD Hospital General Dr Manuel ... papers by this authorMarimar Sáez de Ocariz MD, Marimar Sáez de Ocariz MD Hospital General Dr Manuel ...
Tópico(s): Cutaneous lymphoproliferative disorders research
2012 - Wiley | International Journal of Dermatology
María Vilanova, Josep Vendrell, Marimar LOPEZ, Claudi M. Cuchillo, Francesc Avilés,
A method is reported for the preparative isolation of the two forms of pro-(carboxypeptidase A) from pig pancreas: the monomer and the binary complex with pro-(proteinase E). This method, which is mainly based on chromatography on DEAE-Sepharose at pH 5.7, allows these proenzymes to be prepared more quickly and in safer conditions than with other reported methods. Undegraded and homogeneous carboxypeptidase A1 and A2 species (peptidyl-L-amino acid hydrolase, EC 3.4.17.1), in monomeric forms with ...
Tópico(s): Vitamin K Research Studies
1985 - Portland Press | Biochemical Journal
Sophie Domingues‐Montanari, Israel Fernández‐Cadenas, Alberto del Río-Espínola, Maite Mendióroz, Jessica Fernández‐Morales, Natália Corbeto, Pilar Delgado, Marc Ribó, Marta Rubiera, Vı́ctor Obach, Joan Martí‐Fàbregas, Marimar Freijó, Joaquı́n Serena, Joan Montaner,
Background Genetic factors contribute to the development of ischemic stroke (IS). In order to identify susceptibility variants, we analyzed single nucleotide polymorphisms (SNPs) that had been previously linked to stroke in a genome-wide association study. Methods We analyzed 12 SNPs in a White population comprising IS patients and healthy controls. The analysis was adjusted for confounding variables and stratified by stroke etiology. Functional studies were then performed to elucidate the role of ...
Tópico(s): Genomics and Rare Diseases
2009 - Elsevier BV | Atherosclerosis
Enrique Cases, Luis Seijó, Carlos Disdier, Maria J. Lorenzo, Rosa Cordovilla, Francisca Sanchis, Marimar Lacunza, Gregoria Sevillano, Fátima Benito-Sendín,
Tópico(s): Pneumothorax, Barotrauma, Emphysema
2009 - Elsevier BV | Archivos de Bronconeumología
Enrique Cases, Luis Seijó, Carlos Disdier, Maria J. Lorenzo, Rosa Cordovilla, Francisca Sanchis, Marimar Lacunza, Gregoria Sevillano, Fátima Benito-Sendín,
El objetivo del estudio ha sido analizar la eficacia y seguridad del catéter de drenaje pleural permanente en el manejo de pacientes con diagnóstico de derrame pleural maligno. Se ha realizado un estudio prospectivo y multicéntrico de 63 pacientes consecutivos de 4 hospitales españoles. Se incluyó a 43 varones y 20 mujeres, con una mediana de edad de 67 años, diagnosticados de derrame pleural maligno sintomático. En 7 casos el tratamiento se indicó tras fracaso de pleurodesis, en 5 por encontrarse ...
Tópico(s): Pneumothorax, Barotrauma, Emphysema
2009 - Elsevier BV | Archivos de Bronconeumología
Marimar Sáez‐de‐Ocariz, Carola Durán McKinster, Luz Orozco‐Covarrubias, Lourdes Tamayo‐Sánchez, Ramón Ruiz‐Maldonado,
In addition to onchocerciasis and other filarial diseases, ivermectin has been used for the treatment of scabies, head lice, larva migrans and gnathostomiasis. However, there is concern regarding the safety of its use in children under 5 years of age or weighing less than 15 kg. We present our experience in 18 children (aged 14 months to 17 years), with scabies or cutaneous larva migrans successfully treated with ivermectin. They included four cases of crusted scabies associated with immunosuppression ...
Tópico(s): Insect Utilization and Effects
2002 - Oxford University Press | Clinical and Experimental Dermatology
Yasien Sayed, Judith A. T. Hornby, Marimar LOPEZ, Heini W. Dirr,
In addition to their catalytic functions, cytosolic glutathione S-transferases (GSTs) are a major reserve of high-capacity binding proteins for a large variety of physiological and exogenous non-substrate compounds.This ligandin function has implicated GSTs in numerous ligand-uptake, -transport and -storage processes.The binding of non-substrate ligands to GSTs can inhibit catalysis.In the present study, the energetics of the binding of the non-substrate ligand 8-anilino-1-naphthalene sulphonate (ANS) ...
Tópico(s): Drug Transport and Resistance Mechanisms
2002 - Portland Press | Biochemical Journal
Yasien Sayed, Judith A. T. Hornby, Marimar LOPEZ, Heini W. Dirr,
In addition to their catalytic functions, cytosolic glutathioneS-transferases (GSTs) are a major reserve of high-capacity binding proteins for a large variety of physiological and exogenous non-substrate compounds. This ligandin function has implicated GSTs in numerous ligand-uptake, -transport and -storage processes. The binding of non-substrate ligands to GSTs can inhibit catalysis. In the present study, the energetics of the binding of the non-substrate ligand 8-anilino-1-naphthalene sulphonate ( ...
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2002 - Portland Press | Biochemical Journal
Alberto Capelastegui, Pedro Pablo España, Amaia Bilbao, Marimar Martinez-Vazquez, Inmaculada Gorordo, Mikel Oribe, Isabel Urrutia, José M. Quintana,
A study was undertaken to identify and weigh at the time of hospital discharge simple clinical variables that could predict short-term outcomes in patients with pneumonia.In a prospective observational cohort study of 870 patients discharged alive after hospitalization for pneumonia, we collected oxygenation and vital signs on discharge and assessed mortality and readmission within 30 days. From the beta-parameter obtained in a multivariate Cox proportional hazard regression model, a score was assigned ...
Tópico(s): Respiratory viral infections research
2008 - Elsevier BV | CHEST Journal
Sophie Domingues‐Montanari, Israel Fernández‐Cadenas, Alberto del Río-Espínola, Natália Corbeto, Tiago Krug, Helena Manso, Liliana Gouveia, João Sobral, Maite Mendióroz, Jessica Fernández‐Morales, José Álvarez‐Sabín, Marc Ribó, Marta Rubiera, Vı́ctor Obach, Joan Martí‐Fàbregas, Marimar Freijó, Joaquı́n Serena, José M. Ferro, Astrid M. Vicente, Sofia A. Oliveira, Joan Montaner,
<i>Background:</i> Variants in the 5-lipoxygenase-activating protein <i>(ALOX5AP)</i> and phosphodiesterase 4D <i>(PDE4D)</i> genes have first been associated with ischemic stroke (IS) through whole-genome linkage screens. However, association studies obtained conflicting results. We aimed to investigate the contribution of selected single nucleotide polymorphisms (SNPs) in these genes for the first time in a large Iberian population. <i>Methods:</i> A case-control ...
Tópico(s): Receptor Mechanisms and Signaling
2010 - Karger Publishers | Cerebrovascular Diseases
Marimar Sáez‐de‐Ocariz, Francisco Espinosa‐Rosales, Eduardo López‐Corella, Beatríz de León-Bojorge,
Rarely, systemic lupus erythematosus (SLE) presents with bullous lesions due to severe edema and hydropic degeneration of the basal layer, or as a subepidermal blistering disease. Here, we describe two Mexican teenagers, one with SLE with blisters and another with bullous SLE. We also discuss the mechanisms and clinical implications of lesion formation in patients with SLE and bullae.
Tópico(s): Urticaria and Related Conditions
2010 - BioMed Central | Pediatric Rheumatology
Sophie Domingues‐Montanari, Israel Fernández‐Cadenas, Alberto del Río-Espínola, Maite Mendióroz, Marc Ribó, Vı́ctor Obach, Joan Martí‐Fàbregas, Marimar Freijó, Joaquı́n Serena, Natália Corbeto, Pilar Chacón, José Álvarez‐Sabín, Joan Montaner,
The angiotensin-converting enzyme 1 (ACE1) gene has been extensively studied in stroke, yet generating conflicting results. The goal of our study was thus to clarify the influence of the ACE1 on the risk of suffering an ischaemic stroke (IS).We genotyped the rs4341 (in linkage disequilibrium with the I/D polymorphism) of the ACE1 gene in 531 patients with IS and 549 healthy controls, and the rs1799752 (I/D polymorphism) in a subset of 68 patients with IS and 27 controls. We also performed functional ...
Tópico(s): Receptor Mechanisms and Signaling
2010 - Wiley | European Journal of Neurology
Ramón Ruiz‐Maldonado, Carola Durán‐McKinster, Luz Orozco‐Covarrubias, Marimar Sáez‐de‐Ocariz, Carolina Palacios‐López,
Keratosis lichenoides chronica (KLC) is a rare acquired disease of adulthood, of unknown etiology, characterized by keratotic parallel linear lesions, retiform plaques, and keratotic, often follicular papules, chronicity and lichenoid histopathologic features. KLC of pediatric onset is considered extremely rare. Its features and relationship to adult onset KLC are unknown. We studied 8 cases of pediatric-onset KLC in the literature and 6 personal cases and compared them with 40 reported adult-onset ...
Tópico(s): Genital Health and Disease
2007 - Elsevier BV | Journal of the American Academy of Dermatology
Blanca Fuentes, J. Gállego, Antonio Gil-Núñez, A. Morales, Francisco Purroy, Jaume Roquer, Tomás Segura, J. Tejada, Aída Lago, Exuperio Díez–Tejedor, María Alonso de Leciñana, José Álvarez‐Sabín, Juan F. Arenillas, S. Calleja, I. Casado, Mar Castellanos, José Castillo, A. Dávalos, Fernando Díaz‐Otero, J. Egido, J.C. López-Fernández, Marimar Freijó, Á. García Pastor, F. Gilo, Pablo Irimia, J. Maestre, Jaime Masjuán, Joan Martí‐Fàbregas, Patricia Martínez‐Sánchez, Eduardo Martínez‐Vila, Carlos A. Molina, Florentino Nombela, Marc Ribó, Manuel Rodríguez‐Yáñez, Francisco R. Rubio, Joaquı́n Serena, P. Simal, José Vivancos,
To update the ad hoc Committee of the Cerebrovascular Diseases Study Group of The Spanish Neurological Society guidelines on prevention of ischaemic stroke (IS) and Transient Ischaemic Attack (TIA).We reviewed the available evidence on ischaemic stroke and TIA prevention according to aetiological subtype. Levels of evidence and recommendation levels are based on the classification of the Centre for Evidence-Based Medicine.In atherothrombotic IS, antiplatelet therapy and revascularization procedures ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2011 - Elsevier BV | Neurología
Manuel Rodríguez‐Yáñez, Mar Castellanos, Marimar Freijó, J.C. López Fernández, Joan Martí‐Fàbregas, Florentino Nombela, P. Simal, José Castillo, Exuperio Díez–Tejedor, Blanca Fuentes, María Alonso de Leciñana, José Álvarez‐Sabín, Juan F. Arenillas, S. Calleja, I. González Casado, A. Dávalos, Fernando Díaz‐Otero, J. Egido, J. Gállego, Á. García Pastor, Antonio Gil-Núñez, F. Gilo, Pablo Irimia, Aída Lago, J. Maestre, Jaime Masjuán, Patricia Martínez‐Sánchez, Eduardo Martínez‐Vila, Carlos A. Molina, A. Morales, Francisco Purroy, Marc Ribó, Jaume Roquer, Francisco R. Rubio, Tomás Segura, Joaquı́n Serena, J. Tejada, José Vivancos,
La hemorragia intracerebral sólo representa entre el 10 y el 15% de todos los ictus, sin embargo condiciona un peor pronóstico, con unas tasas más elevadas de morbilidad y mortalidad. Es frecuente que durante las primeras horas tras el inicio de los síntomas se produzca un empeoramiento clínico, lo cual condiciona un peor pronóstico, por lo que la hemorragia intracerebral constituye una emergencia neurológica en la que debe realizarse un diagnóstico y tratamiento adecuado de manera precoz. En esta ...
Tópico(s): Intracranial Aneurysms: Treatment and Complications
2011 - Elsevier BV | Neurología
Blanca Fuentes, J. Gállego, Antonio Gil-Núñez, A. Morales, Francisco Purroy, Jaume Roquer, Tomás Segura, J. Tejada, Aída Lago, Exuperio Díez–Tejedor, María Alonso de Leciñana, José Álvarez‐Sabín, Juan F. Arenillas, S. Calleja, I. Casado, Mar Castellanos, José Castillo, Antoni Dávalos, Fernando Díaz‐Otero, J. Egido, J.C. López-Fernández, Marimar Freijó, Á. García Pastor, F. Gilo, Pablo Irimia, J. Maestre, Jaime Masjuán, Joan Martí‐Fàbregas, Patricia Martínez‐Sánchez, Eduardo Martínez‐Vila, Carlos A. Molina, Florentino Nombela, Marc Ribó, Manuel Rodríguez‐Yáñez, Francisco R. Rubio, Joaquı́n Serena, P. Simal, José Vivancos,
Actualizar las guías terapéuticas del Comité ad hoc del Grupo de Estudio de Enfermedades Cerebrovasculares de la SEN en el tratamiento preventivo de ictus isquémico (II) y ataque isquémico transitorio (AIT). Revisión de evidencias disponibles sobre los factores de riesgo y la oportunidad de su modificación para prevenir el ictus isquémico y AIT. Los niveles de evidencia y grados de recomendación se han basado en la clasificación del Centro de Medicina Basada en la Evidencia. En esta primera parte ...
Tópico(s): Obstructive Sleep Apnea Research
2011 - Elsevier BV | Neurología
Jennifer E. Gagner, Marimar D. Lopez, Jonathan S. Dordick, Richard W. Siegel,
Many biomedical applications of gold nanoparticles (NPs) rely on proteins that are covalently attached or adsorbed on the NP surface. The biological functionality of the protein-NP conjugate depends on the protein’s ability to interact with target molecules, which is affected by NP characteristics such as size, curvature, aspect ratio, morphology, crystal structure, and surface chemistry. In the present study, the effect of gold nanoparticle morphology on the structure and function of adsorbed enzymes, ...
Tópico(s): Nanocluster Synthesis and Applications
2011 - Elsevier BV | Biomaterials
Marco Antonio Yamazaki‐Nakashimada, Samuel Zaltzman-Girshëvich, Silvestre García de la Puente, Beatríz de León-Bojorge, Sara Elva Espinosa‐Padilla, Marimar Sáez‐de‐Ocariz, Daniel Carrasco‐Daza, Víctor Manuel Hernández‐Bautista, L Pérez-Fernández, Francisco Espinosa‐Rosales,
Tópico(s): Platelet Disorders and Treatments
2006 - Springer Science+Business Media | Pediatric Nephrology
Carmen Marcos, Alberto López‐Lera, Susana Varela, Tania Liñares, Marimar G. Alvarez-Eire, Margarita López‐Trascasa,
Background A new variant of hereditary angioedema has been reported during the last decade. Three main characteristics distinguish it from classic hereditary angioedema: normal C1 inhibitor activity, predominance in women, and different genetic alterations. Objective To assess the symptoms, laboratory findings, and treatment of a population with type III hereditary angioedema from Northwest Spain. Methods We studied 29 patients (26 female and 3 male) from 13 different families. Results The 26 female ...
Tópico(s): Autoimmune Bullous Skin Diseases
2012 - Elsevier BV | Annals of Allergy Asthma & Immunology
Blanca Fuentes, J. Gállego, Antonio Gil-Núñez, A. Morales, Francisco Purroy, Jaume Roquer, Tomás Segura, J. Tejada, Aída Lago, Exuperio Díez–Tejedor, María Alonso de Leciñana, José Álvarez‐Sabín, Juan F. Arenillas, S. Calleja, I. González Casado, Mar Castellanos, Juan Enrique Faya Castillo, Antoni Dávalos, Fernando Díaz‐Otero, J. Egido, J.C. López-Fernández, Marimar Freijó, Á. García Pastor, F. Gilo, Pablo Irimia, J. Maestre, Jaime Masjuán, Joan Martí‐Fàbregas, Patricia Martínez‐Sánchez, Eduardo Martínez‐Vila, Carlos A. Molina, Florentino Nombela, Marc Ribó, Manuel Rodríguez‐Yáñez, Francisco R. Rubio, Joaquı́n Serena, P. Simal, José Vivancos,
To update the ad hoc Committee of the Cerebrovascular Diseases Study Group of The Spanish Neurological Society guidelines on prevention of ischaemic stroke (IS) and transient ischaemic attack (TIA). We reviewed available evidence on risk factors and means of modifying them to prevent IS and TIA. Levels of evidence and recommendation grades are based on the classification of the Centre for Evidence-Based Medicine. This first section summarises the recommendations for action on the following factors: ...
Tópico(s): Cardiovascular Health and Disease Prevention
2012 - Elsevier BV | Neurología (English Edition)
Rolando Elias Julián‐Gónzalez, Luz Orozco‐Covarrubias, Carola Durán‐McKinster, Carolina Palacios‐López, Ramón Ruiz‐Maldonado, Marimar Sáez‐de‐Ocariz,
Abstract: The common manifestations of atopic dermatitis (AD) appear sequentially with involvement of the cheeks in infancy, flexural extremities in childhood, and hands in adulthood. Although less common clinical manifestations are well described, they have not been the subject of epidemiologic studies to describe their prevalence in specific age groups. This observational, cross‐sectional, comparative study included 131 children younger than 18 of both sexes with AD who attended the clinics of ...
Tópico(s): Food Allergy and Anaphylaxis Research
2012 - Wiley | Pediatric Dermatology
This study aimed at investigating the perceptions Brazilian pre-service teachers hold concerning the teaching of the four skills in English as a foreign language, with a view to understanding how perceptions relate to pedagogical practice. Data were collected during the pre-service teachers' teaching practicum and the analysis, based on six sets of information, revealed that the pre-service teachers' perceptions stem from two types of knowledge: the theoretical knowledge and the experiential knowledge ...
Tópico(s): Linguistics and Education Research
2005 - | Teaching English as a Second or Foreign Language--TESL-EJ
C. Mauleón-Fernández, Marimar Sáez‐de‐Ocariz, Rodolfo Rodríguez‐Jurado, Carola Durán‐McKinster, Luz Orozco‐Covarrubias, R. Ruiz-Maldonado,
Clinical and Experimental DermatologyVolume 30, Issue 5 p. 595-596 Nodular scabies mimicking urticaria pigmentosa in an infant C. Mauleón-Fernández, C. Mauleón-Fernández Dermatology Department, University Hospital ‘Gregorio Marañón’, Madrid, Spain, *Dermatology Department and †Pathology Department, National Institute of Pediatrics, Mexico City, Mexico E-mail: rrm@servidor.unam.mxSearch for more papers by this authorM. Sáez-de-Ocariz, M. Sáez-de-Ocariz Dermatology Department, University Hospital ‘Gregorio ...
Tópico(s): Bartonella species infections research
2005 - Oxford University Press | Clinical and Experimental Dermatology
Marimar Sáez‐de‐Ocariz, Luz Orozco‐Covarrubias, Ignacio Mora-Magaña, Carola Durán‐McKinster, Lourdes Tamayo‐Sánchez, Pedro Gutiérrez‐Castrellón, Ramón Ruiz‐Maldonado,
Dermatitis artefacta is a factitious disorder in which there is deliberate conscious production of skin lesions. There are only a few reports that evaluate instances of dermatitis artefacta in the pediatric population. The aim of this retrospective study was to assess the characteristics of patients with this disorder who were seen at the National Institute of Pediatrics in Mexico City. The records of all patients diagnosed with dermatitis artefacta from January 1980 to December 1999 were analyzed. ...
Tópico(s): Obsessive-Compulsive Spectrum Disorders
2004 - Wiley | Pediatric Dermatology
Heriberto Vázquez-Flores, Judith Domínguez‐Cherit, María Elisa Vega-Memije, Marimar Sáez‐de‐Ocariz,
Subungual osteochondromas are relatively rare.The objective was to evaluate the clinical, histologic, radiologic, and therapeutic features of subungual osteochondroma.We retrospectively analyzed 27 cases of subungual osteochondroma evaluating the clinical manifestations, the radiologic and histologic features, and the treatment.There were 20 females and 7 males. The first toe was the most commonly involved. Previous trauma was recalled in 40.7% of the cases. Subungual osteochondromas appeared as ...
Tópico(s): Musculoskeletal synovial abnormalities and treatments
2004 - Lippincott Williams & Wilkins | Dermatologic Surgery
Zhengnong Chen, Sampath Chandra Prasad, Filippo Di Lella, Marimar Medina, Enrico Piccirillo, Abdelkader Taibah, Alessandra Russo, Shankai Yin, Mario Sanna,
The authors evaluated the behavior of residual tumors and facial nerve outcomes after incomplete excision of vestibular schwannomas (VSs).The case records of all patients who underwent surgical treatment of VSs were analyzed. All patients in whom an incomplete excision had been performed were analyzed. Incomplete excision was defined as near-total resection (NTR), subtotal resection (STR), and partial resection (PR). Tumors in the NTR and STR categories were followed up with a wait-and-rescan approach, ...
Tópico(s): Neurofibromatosis and Schwannoma Cases
2014 - American Association of Neurological Surgeons | Journal of neurosurgery
Sampath Chandra Prasad, Flavia D’Orazio, Marimar Medina, Andrea Bacciu, Mario Sanna,
Purpose of review To discuss the histological variants, tumor staging, work up and the latest trends in the treatment of malignancies of the temporal bone. Recent findings Because of the rarity of this subset of tumors, there has been no serious attempt to study tumor histologies of the temporal bone other than the squamous cell carcinomas (SCCs). The modified Pittsburgh tumor staging, though popularly used, was primarily developed only for SCC of the external auditory canal. Recent studies have ...
Tópico(s): Ear Surgery and Otitis Media
2014 - Lippincott Williams & Wilkins | Current Opinion in Otolaryngology & Head & Neck Surgery
Sampath Chandra Prasad, Hassen Ait Mimoune, Flavia D’Orazio, Marimar Medina, Andrea Bacciu, Renato Mariani‐Costantini, Paolo Piazza, Mario Sanna,
Objective To define the role of wait-and-scan and radiotherapy (RT) in the treatment of temporal bone paragangliomas and to review the literature on the outcomes of RT as a treatment modality. Materials and Methods This was a retrospective and literature review. The records of 381 patients with 382 tumors between 1988 and 2012 were analyzed. Patients who were subjected to initial wait-and-scan or primary RT were analyzed for tumor response, facial, and lower cranial nerve status on follow-up (FU). ...
Tópico(s): Adrenal and Paraganglionic Tumors
2014 - Lippincott Williams & Wilkins | Otology & Neurotology