Produção Nacional
Revisado por pares
Paulo Leonardo Ponte Marques, Alexandre Braga Libório, Maria Vieira de Lima Saintrain,
Abstract The saliva is important to maintain the integrity of tissues and teeth, besides having microbial activity. Hemodialysis ( HD ) patients usually have reduced salivary flow rate ( SFR ) and are exposed to all its associated complications. The aim of the present study was to identify HD ‐related factors associated with reduced SFR . A cross‐sectional study was performed with maintenance HD patients. Stimulated whole saliva was collected before and after HD . Xerostomia was assessed through the validated ...
Tópico(s): Dental Health and Care Utilization
2014 - Wiley | Artificial Organs
Produção Nacional
Revisado por pares
Gustavo José Luvizutto, T. A. Monteiro, Gabriel Pereira Braga, Octávio Marques Pontes‐Neto, Luiz Antônio de Lima Resende, Rodrigo Bazán,
The objective of this study was to evaluate the consistency, coherence, and interobserver reliability of the Portuguese version of the Scandinavian Stroke Scale (SSS) in a multicultural population of stroke.The SSS was translated, culturally adapted, and applied by two independent investigators. This was a randomized transverse study involving two groups: group 1 included 20 patients in the acute phase and group 2 included 20 patients in the subacute phase after stroke was confirmed by computed tomography ...
Tópico(s): Facial Nerve Paralysis Treatment and Research
2012 - Karger Publishers | Cerebrovascular Diseases Extra
Produção Nacional
Revisado por pares
Anna Carolina Carvalho da Fonseca, Lucas Nicolau de Queiroz, Jéssica Sales Felisberto, Ygor Jessé Ramos, André Mesquita Marques, Guilherme Freimann Wermelinger, Bruno Pontes, Davyson de Lima Moreira, Bruno Kaufmann Robbs,
The oral squamous cell carcinoma (OSCC) is the eighth more common cancer in men. The development of new and more efficient drugs is needed. Plants of the genus Piper are popularly used in the treatment of many diseases. This study evaluated the antitumor effect of extract, fraction and isolated compounds from leaves of P. rivinoides in oral cancer. The isolated compounds (conocarpan, eupomatenoid-5 and eupomatenoid-6) were effective in inducing cell death in OSCC cell lines (SCC4, SCC9 and SCC25) compared ...
Tópico(s): Ginger and Zingiberaceae research
2020 - Taylor & Francis | Natural Product Research
Produção Nacional
Revisado por pares
Terezinha Souza, Davi Felipe Farias, Bruno Marques Soares, Martônio Ponte Viana, Glauber Pacelli Gomes de Lima, Lyeghyna K.A. Machado, Selene Maia de Morais, Ana Fontenele Urano Carvalho,
Seed ethanolic extracts of 21 Brazilian plants were evaluated for ovicidal, larvicidal, and pupicidal activities against insecticide-susceptible (SS) and field-collected (FC) strains of Aedes aegypti (L.) (Diptera: Culicidae), as well as for their effects on nontarget organisms. Myracrodruon urundeuva Fr. Allemao extract was highly toxic to both mosquito strains. Schinopsis brasiliensis Engler extract showed low toxicity and was 38–68 times less toxic to Ae. aegypti larvae than was M. urundeuva extract. ...
Tópico(s): Insect and Pesticide Research
2011 - Oxford University Press | Journal of Medical Entomology
Produção Nacional
Revisado por pares
Élida Lívia Rafael Dantas, Fernando Henrique de Lima Sá, Sionara Melo de Figueiredo de Carvalho, Anderson Pontes Arruda, Evelane Marques Ribeiro, Erlane Marques Ribeiro,
Atualmente, o câncer é a doença que mais causa mortes no mundo. Devido a isso, ele tem sido alvo de inúmeras pesquisas, entre as quais se descobriu sua relação com a hereditariedade. Sabe-se que o câncer decorre de alterações em oncogenes, em genes pertencentes ao grupo supressor tumoral ou em genes do grupo que repara o DNA. Muitos desses genes já foram descobertos, identificados e relacionados a certos tipos de câncer. Esses achados proporcionaram a utilização de novos métodos de diagnóstico e ...
Tópico(s): Genomic variations and chromosomal abnormalities
2009 - | Revista Brasileira de Cancerologia
Produção Nacional
Revisado por pares
Renata Monteiro Lima, Maria Augusta Drago Ferreira, Teresa Maria de Jesus Ponte, Maria Paula Marques, Osvaldo Massaiti Takayanagui, Hector Hugo Garcia, Eduardo Barbosa Coelho, Pierina Sueli Bonato, Vera Lúcia Lanchote,
A simple enantioselective method for the determination of praziquantel (PZQ) and trans-4-hydroxypraziquantel (4-OHPZQ) in human plasma was developed and validated by high-performance liquid chromatography/mass spectrometry. The plasma samples were prepared by liquid–liquid extraction using a mixture of methyl-tert-butylether/dichloromethane (2:1, v/v) as extraction solvent. The direct resolution of PZQ and 4-OHPZQ enantiomers was performed on a Chiralpak AD column using hexane–isopropanol (75:25, v/ ...
Tópico(s): Microfluidic and Capillary Electrophoresis Applications
2009 - Elsevier BV | Journal of Chromatography B
Produção Nacional
Revisado por pares
Juliana Pires Viana de Jesus, Aline Lima-Matos, Paula Almeida, Valmar Bião Lima, Luane Marques de Mello, Adelmir Souza‐Machado, Eduardo Vieira Ponte, Álvaro A. Cruz,
To evaluate the relationship between obesity and asthma.This was a preliminary cross-sectional analysis involving 925 subjects with mild-to-moderate or severe asthma evaluated between 2013 and 2015. Obesity was defined on the basis of body mass index (BMI) and abdominal circumference. We collected clinical, laboratory, and anthropometric parameters, as well as pulmonary function test results and data regarding comorbidities. The subjects also completed asthma control and quality of life questionnaires. ...
Tópico(s): Respiratory and Cough-Related Research
2018 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Produção Nacional
Revisado por pares
Natália Pontes Lima, Gregório Marques Cardim da Silva, Marcelo Park, Ruy Camargo Pires-Neto,
OBJECTIVE: To determine whether mobility therapy is associated with central or peripheral catheter-related adverse events in critically ill patients in an ICU in Brazil. METHODS: A retrospective analysis of the daily medical records of patients admitted to the Clinical Emergency ICU of the University of São Paulo School of Medicine Hospital das Clínicas Central Institute between December of 2009 and April of 2011. In addition to the demographic and clinical characteristics of the patients, we collected ...
Tópico(s): Healthcare Decision-Making and Restraints
2015 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Produção Nacional
Revisado por pares
Roberto César Pereira Lima‐Júnior, Aline Almeida Figueiredo, H. Freitas, Maria Luísa Pereira de Melo, Deysi Viviana Tenazoa Wong, Caio A. Leite, Rui Medeiros, Raphael Dias Marques-Neto, Mariana Lima Vale, Gerly Anne de Castro Brito, Reinaldo B. Oriá, Marcellus Henrique Loiola Ponte de Souza, Fernando Q. Cunha, Ronaldo A. Ribeiro,
Tópico(s): Head and Neck Surgical Oncology
2011 - Springer Science+Business Media | Cancer Chemotherapy and Pharmacology
Rodrigo Tavares Brisson, Renata da Silva Almeida Santos, Luiz Henrique Soares Santos Stefano, Clara Barreira, Josevânia Fulgêncio de Lima Arruda, Francisco Antunes Dias, Millene Rodrigues Camilo, Octávio Marques Pontes‐Neto,
Transcranial color-coded Doppler (TCCD) is an ultrasonographic technique used to obtain and evaluate images of the cerebral parenchyma and to assess blood flow velocities of the intracranial vessels. One of the major limitations of TCCD is the failure to insonate through the transtemporal window, which occurs in about 5%-44% of patients. Temporal bone thickness has been strongly associated with transtemporal window failure (TWF). The aims of the study were to evaluate the association between TWF on ...
Tópico(s): Acute Ischemic Stroke Management
2020 - Elsevier BV | Ultrasound in Medicine & Biology
Produção Nacional
Revisado por pares
Kellyanne dos Anjos Carvalho, Osvaldo P. de Melo Neto, Franklin Barbalho Magalhães, João Carlos Marques Ponte, Filipe Adriano Borba Felipe, Mariese Conceição Alves dos Santos, Givaneide dos Santos Lima, Álvaro A. Cruz, Carina S. Pinheiro, Lain Carlos Pontes-de-Carvalho, Neuza Maria Alcântara‐Neves,
Abstract Background Blomia tropicalis is a dust mite and an important source of allergens in tropical regions. Up to now, the assays to diagnose atopy to this mite use whole body extract as antigens. However, anti- B. tropicalis IgE antibodies cross-react with Ascaris lumbricoides antigens, hindering the diagnosis of allergy to this mite. In this study, B. tropicalis recombinant allergens were evaluated with the purpose of developing an immunodiagnostic assay for allergy to this mite with greater ...
Tópico(s): Contact Dermatitis and Allergies
2013 - BioMed Central | BMC Immunology
Produção Nacional
Revisado por pares
Maria Vieira de Lima Saintrain, Paulo Leonardo Ponte Marques, Lúcio Hélio Pereira de Almeida, Caroline Barbosa Lourenço, Raimunda Magalhães da Silva, Anya Pimentel Gomes Fernandes Vieira,
Relação entre o gênero no acesso ao serviço odontológico e aos artigos de higiene bucal La
Tópico(s): Dental Education, Practice, Research
2014 - UNIVERSIDADE DE FORTALEZA | Revista Brasileira em Promoção da saúde
Produção Nacional
Revisado por pares
Gustavo José Luvizutto, Maicon Gonçalves Gabriel, Gabriel Pereira Braga, Thiago Dias Fernandes, Luiz Antônio de Lima Resende, Octávio Marques Pontes‐Neto, Rodrigo Bazán,
To investigate the correlation between the Alberta Program Early CT Score (ASPECTS) and the Scandinavian Stroke Scale (SSS) for the evaluation of neurological impairment in patients with acute stroke.59 patients with a first acute ischemic stroke were evaluated. The ASPECTS were evaluated by 2 neurologists at admission and by another neurologist after 48 hours. The NIHSS and SSS was applied to determinate stroke severity. Correlations and agreements were analysed statistically by Spearman and Kappa ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2015 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
Aline Lima-Matos, Eduardo Vieira Ponte, Juliana Pires Viana de Jesus, Paula Almeida, Valmar Bião Lima, Namhee Kwon, John Riley, Luane Marques de Mello, Álvaro A. Cruz,
Asthma is a syndrome with multiple phenotypes. Peripheral blood eosinophil counts might be the ideal biomarker to identify subjects with eosinophilic asthma. It is available, inexpensive, and it is associated with eosinophilia in sputum.The aim of this study was to evaluate whether blood eosinophilia is associated with asthma severity and to evaluate whether blood eosinophilia is associated with lack of control of asthma symptoms and airway obstruction.Case control study. The cases were subjects ...
Tópico(s): Respiratory and Cough-Related Research
2018 - Elsevier BV | Respiratory Medicine
Produção Nacional
Revisado por pares
Rodrigo Bazán, Gustavo José Luvizutto, Gabriel Pereira Braga, Silméia Garcia Zanati Bazan, João Carlos Hueb, Carlos Clayton Macedo de Freitas, Pedro Tadao Hamamoto Filho, Gabriel Pinheiro Módolo, André Petean Trindade, Marcone Lima Sobreira, Hélio Rubens de Carvalho Nunes, João Pereira Leite, Octávio Marques Pontes‐Neto,
Abstract Introduction The presence of microembolic signals (MES) during the acute phase of stroke is poorly understood, and its role and clinical application in relation to risk stratification and prognosis in patients remain uncertain. We assessed the prevalence of spontaneous MES in acute stroke and their relationship with risk stratification, stroke recurrence, morbidity, and mortality. Patients and methods This was a prospective cohort study conducted in the Stroke Unit. The MES presence was ...
Tópico(s): Cardiovascular Health and Disease Prevention
2020 - Springer Nature | The Ultrasound Journal
Produção Nacional
Revisado por pares
Viviane Flumignan Zétola, Marcos Christiano Lange, Valéria Cristina Scavasine, Rodrigo Bazán, Gabriel Pereira Braga, Ana Claúdia Celestino Bezerra Leite, Soraia Ramos Cabette Fábio, Octávio Marques Pontes‐Neto, Carla Heloísa Cabral Moro, Gisele Sampaio, Edson Bor-Seng Shu, Marcelo de Lima Oliveira, Maramélia Miranda, Daniela Laranja Gomes, Pedro Antônio Pereira de Jesus, Jamary Oliveira‐Filho, Wagner Mauad Avelar, Gabriel R. de Freitas, Rafael Borsoi, Corina Puppo, Silvia Cocorullo, Alejandro M. Brunser, Ayrton Roberto Massaro, Natan M. Bornstein, Alexander Y. Razumovsky, Massimo Del Sette,
The role of patent foramen ovale is a field of debate and current publications have increasing controversies about the patients' management in young undetermined stroke. Work up with echocardiography and transcranial Doppler (TCD) can aid the decision with better anatomical and functional characterization of right-to-left shunt (RLS). Medical and interventional strategy may benefit from this information.a group of experts from the Latin American participants of the Neurosonology Research Group (NSRG) ...
Tópico(s): Cardiovascular Health and Disease Prevention
2019 - Karger Publishers | Cerebrovascular Diseases
Produção Nacional
Revisado por pares
Tiago Lima de Albuquerque, Sandy Danielle Luncindo Gomes, José Edvan Marques, Ivanildo José da Silva, Maria Valderez Ponte Rocha,
The production of xylitol, a polyol with high employability in the food and pharmaceutical industry, from cashew apple bagasse hydrolysate (CABH) by a new strain of Kluyveromyces marxianus was studied. Initially, the use of activated charcoal in the detoxification of hydrolysates from CABH was evaluated. Then, the influence of the supplementation of CABH with various nitrogen sources was studied. The activated charcoal reduced the concentration of acid and phenolic compounds. K. marxianus CCA510 ...
Tópico(s): Enzyme Production and Characterization
2014 - Elsevier BV | Catalysis Today
Produção Nacional
Revisado por pares
Tiago Lima de Albuquerque, José Edvan Marques Júnior, Lívia Pinheiro de Queiroz, Anderson Diógenes Souza Ricardo, Maria Valderez Ponte Rocha,
Polylactic acid (PLA) has been highlighted as an important polymer due to its high potential for applicability in various areas, such as in the chemical, medical, pharmaceutical or biotechnology field. Very recently, studies have reported its use as a basic component for the production of personal protective equipment (PPE) required for the prevention of Sars-Cov-2 contamination, responsible for the cause of coronavirus disease, which is currently a major worldwide sanitary and social problem. PLA ...
Tópico(s): Enzyme Catalysis and Immobilization
2021 - Elsevier BV | International Journal of Biological Macromolecules
Produção Nacional
Revisado por pares
Fernando G. Zampieri, Flávia Ribeiro Machado, Rodrigo Biondi, F Freitas, Viviane Cordeiro Veiga, Rodrigo C. Figueiredo, Wilson José Lovato, Cristina Prata Amêndola, Murillo Santucci César de Assunção, Ary Serpa Neto, Jorge L. R. Paranhos, José Andrade, Michele Maria Gonçalves de Godoy, Edson Romano, Felipe Dal‐Pizzol, Emerson Barbosa da Silva, Miquéias M.L. Silva, Miriam Machado, Luíz Marcelo Sá Malbouisson, Airton L. O. Manoel, Marlus M. Thompson, Lanese Medeiros de Figueiredo, Rafael Marques Soares, Tamiris Abait Miranda, Lucas Martins de Lima, Eliana Vieira Santucci, Thiago Domingos Corrêa, Luciano César Pontes Azevedo, John A. Kellum, Lucas Petri Damiani, Nilton B. Silva, Alexandre Biasi Cavalcanti, Rodrigo Biondi, Bruno C. R. Amaral, Edvar Ferreira R., Andrea Z. Abdalla, Flávio Geraldo Rezende Freitas, Nathaly Fonseca Nunes, Rodrigo C. da Cunha, Elijane F. Alves, Rodrigo C. Figueiredo, Rodrigo B. Bortolini, Cintia L. Sartori, Eduardo S. Marques, Maria Auxiliadora de Sousa, Danieri Y. V. Tomotani, Airton L. O. Manoel, Wilson José Lovato, Bruno G. Dantas, Leonardo Carvalho Palma, Fabio Laurindo Silva, Cristina Prata Amêndola, Luciana Coelho Sanches, Fernanda A. M. Scuoteguazza, Ligia Z. de Britto, Ary Serpa, Niklas Söderberg Campos, Fábio Barlem Hohmann, Guilherme Benfatti Olivato, Jorge L. R. Paranhos, Iany G. da Silva, Adilson de C. Meireles, Viviane Cordeiro Veiga, Juliana Chaves Coelho, Maiko Moura Silveira, Agnes C. Lisboa, Marco A.V. Guedes, Luíz Carlos Santana Passos, Daniela C. Dorta, Ramana A. Rangel, Péricles Almeida Delfino Duarte, Eraldo de Azevedo Lúcio, Eduardo B. Tondo, Pablo A.A. Vaz, Paula K. de Oliveira, Lúcio Couto de Oliveira, Paulo H.P. Ferreira, Patrick Harrison Santana Sampaio, Maurício G.S. Serra, Thiago Lisboa, Caroline Fachini, André P. Torelly, Alldren Souza, Fábio Holanda Lacerda, Eliana V. N. Martins, Bruno Adler Maccagnan Pinheiro Besen, Carlos Eduardo Brandão, João Manoel Silva, Flávio W.F. Melo, Flávio A. dos Santos, Israel Silva Maia, Cássio Luis Zandonai, Eduardo Berbigier, Cíntia Magalhães Carvalho Grion, Josiane Festti, Ana Luiza Mezzaroba, José Andrade, Marianne Camargo, Adriano F. Teixeira, José de S. Andrade, Michele Maria Gonçalves de Godoy, Andréia de F. T. de Mendonça, Mara L.F.S. Mendes, Renata C.I.C. Beltrão, Edson Romano, Marcelo Luz Pereira Romano, André Falcão Pedrosa Costa, Jorge Farran, Felipe Dal‐Pizzol, Danusa Damásio, Renata Casagrande Gonçalves, Emerson Boschi, Luiz de F. Ferreira, Rafael Lessa da Costa, Kellen Lopes, Miquéias M.L. Silva, Douglas L.A.B. de Matos, Renata de A. Marques, Glauco Adrieno Westphal, Miriam Machado, Juliano Ramos, Luíz Marcelo Sá Malbouisson, Bruno N. Lucena, Marlus M. Thompson, Lanese Medeiros de Figueiredo, Luana Feitosa Mourão, Thiago Santos Garcês, Israel da S. Maia, Jaqueline F. Rohr, Fernanda Fontanela, Cassia P. B. Martins, Álvaro Réa-Neto, Fernanda Baeumle Reese, Mirella Cristine de Oliveira, André Luiz Nunes Gobatto, Luciana S. de Mattos, Carolaine B. de Oliveira, Meton S. de Alencar, Jussara Alencar Arraes, João G.T. Alves, Thiago C. De Morais, Antônio A. P. Fagundes, Roberta T. Tallarico, Thais Coutinho, Ronald Torres, Fernando J. S. Ramos, Fernanda C. Athalla, Mauricio H.C. dos Santos, Paulo Maurício Garcia Nosé, Cássia Righy Shinotsuka, Pedro Kurtz, Bruno Guimarães, Luciana Guilhermino Pereira, Raquel B. Jupato, Bruno de Arruda Bravim, Marcos Freitas Knibel, Allan S. da Silva, Vinícius G. de Luca, Niklas Soderberg, Roseny dos Reis Rodrigues, Luis E.P. Pfingsten, Cassiano Teixeira, José H.D. Barth, Giselle C. Pratini, Luiz Dalfior, Márcio H. Kai, S Blecher, Hugo C. A. Urbano, Lucas L. Carvalho, Danielle C. A. Moreira, Ana L. S. Bernardes, Vandack Nobre, Paula Frizera Vassallo, Cecilia Gómez Ravetti, Ho Y. Li, Vivian Vieira Tenório Sales, Renata Guazzelli, Rafael David de Oliveira, Leandro Pozzo, Leandro Utino Taniguchi, Pedro Vitale Mendes, Suzana M Lobo, Miriam Machado, Ana B. B. Camacho, Pablo Oscar Tomba, Fred C. T. Lizidatti, Walter C. G. Baptista, Aline R. Moreira, Manoela M. de Sousa, Marcelo de Oliveira Santos, Karla Moretto, Priscilla A. de Martins, Liz M. L. de Souza, Thiago R. Sequeira, Manoel M. S. Pedrinha, Marcone L. S. da Rocha, Francisco R. V. Saleiro, Tatiana M. Clementino, Hélio Penna Guimarães, Marcos Cesar Ramos Mello, Mirella Cristine de Oliveira, Fernanda Baeumle Reese, Denise Milioli Ferreira, Fernanda Alves Ferreira Gonçalves, Roberta Muriel Longo Roepke, Bruno Martins Tomazini, Sidiner Mesquita Vaz, Miria Bonjour Laviola, Thiago Domingos Corrêa, Roger Monteiro Alencar, Denise N. Freitas, Heitor P. Póvoas, Liliane B. S. Passos, Juliane de M. Silva,
Slower intravenous fluid infusion rates could reduce the formation of tissue edema and organ dysfunction in critically ill patients; however, there are no data to support different infusion rates during fluid challenges for important outcomes such as mortality.To determine the effect of a slower infusion rate vs control infusion rate on 90-day survival in patients in the intensive care unit (ICU).Unblinded randomized factorial clinical trial in 75 ICUs in Brazil, involving 11 052 patients requiring ...
Tópico(s): Respiratory Support and Mechanisms
2021 - American Medical Association | JAMA
Produção Nacional
Revisado por pares
F. Mont’alverne, Fabrício Oliveira Lima, Raul G. Nogueira, Carlos Clayton Macedo de Freitas, Octávio Marques Pontes‐Neto, Gisele Sampaio Silva, Maura Salaroli de Oliveira, Michel Eli Frudit, José Guilherme Mendes Pereira Caldas, Daniel Giansante Abud, Adriana Bastos Conforto, Fernanda Carvalho, Francisco Antunes Dias, Rodrigo Bazán, Wagner Mauad Avelar, Carla Heloísa Cabral Moro, Pedro Magalhães, Maramélia Miranda, Leandro de Assis Barbosa, José Antônio Fiorot Júnior, Fabrício Bruno Cardoso, Letícia Costa Rebello, Bruno de Sousa Mendes Parente, Mario Faria, Gabriel R. de Freitas, Viviane Flumignan Zétola, Jamary Oliveira‐Filho, Daniel Bezerra, Jorge Luis Nobre RODRIGUES, Gustavo W. Kuster, Sheila Cristina Ouriques Martins, João José Freitas de Carvalho,
Introduction: Although the 2019 severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2, COVID-19) pandemic poses new challenges to the healthcare system to provide support for thousands of patients, there is special concern about common medical emergencies, such as stroke, that will continue to occur and will require adequate treatment. The allocation of both material and human resources to fight the pandemic cannot overshadow the care for acute stroke, a time-sensitive emergency that ...
Tópico(s): Long-Term Effects of COVID-19
2020 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
Flavia M. N. P. Aslanian, Maria Teresa Queiroz Marques, Haroldo José de Matos, Luciane F. S. Pontes, Luís Cristóvão Pôrto, Lúcia Maria Soares de Azevedo, Absalom Lima Filgueira,
Summary Background: Lichen sclerosus (LS) has been identified with increased frequency in families,often associated with HLA markers, mainly DQ7. A genetic co‐etiology seems likely in this setting. Moreover, there is an association of LS with autoimmune disorders, such as the presence of anti‐thyroid peroxidase autoantibodies (anti‐TPO), a hallmark of autoimmune thyroid diseases. Patients and Methods: In 3 families affected by LS, we verified their HLA markers, and identified previously undiagnosed ...
Tópico(s): American Sports and Literature
2006 - Wiley | JDDG Journal der Deutschen Dermatologischen Gesellschaft
Produção Nacional
Revisado por pares
Álvaro A. Cruz, John Riley, Aruna T. Bansal, Eduardo Vieira Ponte, Adelmir Souza‐Machado, Paula Almeida, Valmar Bião Lima, Maggie Davis, Stewart Bates, Ian M. Adcock, Peter J. Sterk, Kian Fan Chung, Neuza Maria Alcântara‐Neves, Paula Almeida, Leila Denise Alves Ferreira Amorim, Maria Ilma Araújo, Kathleen C. Barnes, Maurício L. Barreto, Emília Maria Medeiros de Andrade Belitardo, Valmar Bião Lima, Luciana Santos Cardoso, Paulo Augusto Moreira Camargos, José Miguel Chatkin, Rosanne Costa, Ana Carla Carvalho Coelho, Philip J. Cooper, Álvaro A. Cruz, Constança Sampaio Cruz, João Pedro Arantes da Cunha, J.V. de Jesus, Jamille Souza Fernandes, Rosana Franco, Isaac Suzart Gomes‐Filho, Aline Lima-Matos, Camila Alexandrina Figueiredo, M.A. Lessa, Liliane Lins-Kusterer, Luane Marques de Mello, P. Moura-Santos, Ila Sobral Muniz, I. Paixao-Araujo, Gabriela Pimentel Pinheiro, Eduardo Vieira Ponte, Liziane Rodrigues, Cínthia Vila Nova Santana, Gustavo Z Dos Santos-Lima, T.M.O. Souza, Adelmir Souza‐Machado, Carolina Souza‐Machado, Rafaël Stelmach, Víctor Vásquez, Ian M. Adcock, Hassan Ahmed, Charles Auffray, Per Bakke, Fred Baribaud, EH Bel, Jeanette Bigler, Hans Bisgaard, Michael Boedigheimer, Klaus Bønnelykke, Joost Brandsma, Paul Brinkman, Enrica Bucchioni, Dominic Burg, Andrew Bush, Massimo Caruso, Amphun Chaiboonchoe, Pascal Chanez, C.H. Compton, Julie Corfield, A. D’Amico, Barbro Dahlén, Sven‐Erik Dahlén, Bertrand De Meulder, Ratko Djukanović, V.J. Erpenbeck, Damijan Eržen, K. Fichtner, Neil Fitch, Louise Fleming, E. Formaggio, Stephen J. Fowler, Urs Frey, Martina Gahlemann, Thomas Geiser, Victoria Goss, Yi Ke Guo, Simone Hashimoto, John Haughney, Gunilla Hedlin, Pieter‐Paul Hekking, T. W. Higenbottam, J.M. Hohlfeld, Cécile Holweg, Ildikó Horváth, Peter Howarth, A.J. James, Richard G. Knowles, Alan J. Knox, N Krug, Diane Lefaudeux, Matthew J. Loza, R. Lutter, Alexander Manta, Sarah Masefield, J.G. Matthews, Alexander Mazein, Andrea Meiser, Roelinde Middelveld, M. Miralpeix, Paolo Montuschi, Nadia Mores, Clare Murray, J. Musial, David Myles, Laurie Pahus, Ioannis Pandis, Stelios Pavlidis, Anthony D. Postle, P. Powel, G. Praticò, M. Puig Valls, Navin Rao, Amanda Roberts, Graham Roberts, Anthony Rowe, Thomas Sandström, James Schofield, Wolfgang Seibold, Anna Selby, Dominick Shaw, Ralf Sigmund, Florian Singer, Paul Skipp, Ana R. Sousa, Peter J. Sterk, Kai Sun, Bob Thornton, W. M. van Aalderen, Marleen van Geest, Jørgen Vestbo, Nadja Hawwa Vissing, Ariane H. Wagener, Scott Wagers, Z. Weiszhart, Craig E. Wheelock, Susan J. Wilson,
BackgroundAsthma prevalence is 339 million globally. 'Severe asthma' (SA) comprises subjects with uncontrolled asthma despite proper management.ObjectivesTo compare asthma from diverse ethnicities and environments.MethodsA cross-sectional analysis of two adult cohorts, a Brazilian (ProAR) and a European (U-BIOPRED). U-BIOPRED comprised of 311 non-smoking with Severe Asthma (SAn), 110 smokers or ex-smokers with SA (SAs) and 88 mild to moderate asthmatics (MMA) while ProAR included 544 SA and 452 MMA. Although ...
Tópico(s): Delphi Technique in Research
2019 - Elsevier BV | Respiratory Medicine
Produção Nacional
Revisado por pares
Fernando G. Zampieri, Flávia Ribeiro Machado, Rodrigo Biondi, Flávio Geraldo Rezende Freitas, Viviane Cordeiro Veiga, Rodrigo C. Figueiredo, Wilson José Lovato, Cristina Prata Amêndola, Ary Serpa Neto, Jorge L. R. Paranhos, Marco A.V. Guedes, Eraldo A. Lúcio, Lúcio C. Oliveira-Júnior, Thiago Lisboa, Fábio Holanda Lacerda, Israel Silva Maia, Cíntia Magalhães Carvalho Grion, Murillo Santucci César de Assunção, Airton L. O. Manoel, João Manoel Silva, Péricles Almeida Delfino Duarte, Rafael Marques Soares, Tamiris Abait Miranda, Lucas Martins de Lima, Rodrigo M. Gurgel, Denise Paisani, Thiago Domingos Corrêa, Luciano César Pontes Azevedo, John A. Kellum, Lucas Petri Damiani, Nilton Brandão da Silva, Alexandre Biasi Cavalcanti, Rodrigo Biondi, Renato Bueno Chaves, Amanda Ribeiro dos Santos, Vitor Salvatore Barzilai, Flávio Geraldo Rezende Freitas, Nathaly Fonseca Nunes, Rodrigo C. da Cunha, Elijane F. Alves, Rodrigo C. Figueiredo, Rodrigo B. Bortolini, Cintia L. Sartori, Eduardo S. Marques, Maria Auxiliadora de Sousa, Danieri Y. V. Tomotani, Airton L. O. Manoel, Wilson José Lovato, Bruno G. Dantas, Leonardo Carvalho Palma, Fabio Laurindo Silva, Cristina Prata Amêndola, Luciana Coelho Sanches, Fernanda A. M. Scuoteguazza, Ligia Z. de Britto, Ary Serpa, Niklas Söderberg Campos, Fábio Barlem Hohmann, Guilherme Benfatti Olivato, Jorge L. R. Paranhos, Iany G. da Silva, Adilson de C. Meireles, Viviane Cordeiro Veiga, Juliana Chaves Coelho, Maiko Moura Silveira, Agnes C. Lisboa, Marco A.V. Guedes, Luíz Carlos Santana Passos, Daniela C. Dorta, Ramana A. Rangel, Péricles Almeida Delfino Duarte, Eraldo de Azevedo Lúcio, Eduardo B. Tondo, Pablo A.A. Vaz, Paula K. de Oliveira, Lúcio Couto de Oliveira, Paulo H.P. Ferreira, Patrick Harrison Santana Sampaio, Maurício G.S. Serra, Thiago Lisboa, Caroline Fachini, André P. Torelly, Alldren Souza, Fábio Holanda Lacerda, Eliana V. N. Martins, Bruno Adler Maccagnan Pinheiro Besen, Carlos Eduardo Brandão, João Manoel Silva, Flávio W.F. Melo, Flávio A. dos Santos, Israel Silva Maia, Cássio Luis Zandonai, Eduardo Berbigier, Cíntia Magalhães Carvalho Grion, Josiane Festti, Ana Luiza Mezzaroba, José Andrade, Marianne Camargo, Adriano F. Teixeira, José de S. Andrade, Michele Maria Gonçalves de Godoy, Andréia de F. T. de Mendonça, Mara L.F.S. Mendes, Renata C.I.C. Beltrão, Edson Romano, Marcelo Luz Pereira Romano, André Falcão Pedrosa Costa, Jorge Farran, Felipe Dal‐Pizzol, Danusa Damásio, Renata C. Gonçalves, Emerson Boschi, Luiz de F. Ferreira, Rafael Lessa da Costa, Kellen Lopes, Miquéias M.L. Silva, Douglas L.A.B. de Matos, Renata de A. Marques, Glauco Adrieno Westphal, Miriam Machado, Juliano Ramos, Luíz Marcelo Sá Malbouisson, Bruno N. Lucena, Marlus M. Thompson, Lanese Medeiros de Figueiredo, Luana Feitosa Mourão, Thiago Santos Garcês, Israel da S. Maia, Jaqueline F. Rohr, Fernanda Fontanela, Cassia P. B. Martins, Álvaro Réa-Neto, Fernanda Baeumle Reese, Mirella Cristine de Oliveira, André Luiz Nunes Gobatto, Luciana S. de Mattos, Carolaine B. de Oliveira, Meton S. de Alencar, Jussara Alencar Arraes, João G.T. Alves, Thiago C. De Morais, Antônio A. P. Fagundes, Roberta T. Tallarico, Thais Coutinho, Ronald Torres, Fernando J. S. Ramos, Fernanda C. Athalla, Mauricio H.C. dos Santos, Paulo Maurício Garcia Nosé, Cássia Righy Shinotsuka, Pedro Kurtz, Bruno Guimarães, Luciana Guilhermino Pereira, Raquel B. Jupato, Bruno de Arruda Bravim, Marcos Freitas Knibel, Allan S. da Silva, Vinícius G. de Luca, Niklas Soderberg, Roseny dos Reis Rodrigues, Luis E.P. Pfingsten, Cassiano Teixeira, José H.D. Barth, Giselle C. Pratini, Luiz Dalfior, Márcio H. Kai, S Blecher, Hugo C. A. Urbano, Lucas L. Carvalho, Danielle C. A. Moreira, Ana L. S. Bernardes, Vandack Nobre, Paula Frizera Vassallo, Cecilia Gómez Ravetti, Ho Y. Li, Vivian Vieira Tenório Sales, Renata Guazzelli, Rafael David de Oliveira, Leandro Pozzo, Leandro Utino Taniguchi, Pedro Vitale Mendes, Suzana M Lobo, Miriam Machado, Ana B. B. Camacho, Pablo Oscar Tomba, Fred C. T. Lizidatti, Walter C. G. Baptista, Aline R. Moreira, Manoela M. de Sousa, Marcelo de Oliveira Santos, Karla Moretto, Priscilla A. de Martins, Liz M. L. de Souza, Thiago R. Sequeira, Manoel M. S. Pedrinha, Marcone L. S. da Rocha, Francisco R. V. Saleiro, Tatiana M. Clementino, Hélio Penna Guimarães, Marcos Cesar Ramos Mello, Mirella Cristine de Oliveira, Fernanda Baeumle Reese, Denise Milioli Ferreira, Fernanda Alves Ferreira Gonçalves, Roberta Muriel Longo Roepke, Bruno Martins Tomazini, Sidiner Mesquita Vaz, Miria Bonjour Laviola, Thiago Domingos Corrêa, Roger Monteiro Alencar, Denise N. Freitas, Heitor P. Póvoas, Liliane B. S. Passos, Juliane de M. Silva,
Importance Intravenous fluids are used for almost all intensive care unit (ICU) patients. Clinical and laboratory studies have questioned whether specific fluid types result in improved outcomes, including mortality and acute kidney injury. Objective To determine the effect of a balanced solution vs saline solution (0.9% sodium chloride) on 90-day survival in critically ill patients. Design, Setting, and Participants Double-blind, factorial, randomized clinical trial conducted at 75 ICUs in Brazil. Patients ...
Tópico(s): Acute Kidney Injury Research
2021 - American Medical Association | JAMA
Produção Nacional
Revisado por pares
João Brainer Clares de Andrade, J.P. Mohr, Fabrício Oliveira Lima, João José Freitas de Carvalho, Victor A. E. Farias, Jamary Oliveira‐Filho, Octávio Marques Pontes‐Neto, Rodrigo Bazán, Kristel Larisa Back Merida, Luisa Franciscato, Matheus Mendes Pires, Gabriel Pinheiro Módolo, Mayara Silva Marques, Renata Carolina Acri Nunes Miranda, Gisele Sampaio Silva,
Well studied in patients with ischemic stroke after reperfusion therapies (RT), hemorrhagic transformation (HT) is also common in patients not treated with RT and can lead to disability even in initially asymptomatic cases. The best predictors of HT in patients not treated with RT are not well established. Therefore, we aimed to identify predictors of HT in patients not submitted to RT and create a user-friendly predictive score (PROpHET).Patients admitted to a Comprehensive Stroke Center from 2015 ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2020 - Elsevier BV | Journal of Stroke and Cerebrovascular Diseases
Produção Nacional
Revisado por pares
Edinilze Souza Coelho Oliveira, Leonard Domingo Rosales Acho, Bárbara Janaína Paula da Silva, Ruben Dario Morales-Gamba, Flávia Sirotheau Corrêa Pontes, Alessandro Silva do Rosário, Jaqueline de Araújo Bezerra, Francinete Ramos Campos, José Fernando Marques Barcellos, Émerson Silva Lima, Marcos B. Machado,
The leaves of Eugenia biflora (Myrtaceae) are traditionally used by Amazonian populations for the control of diabetes. However, their chemical composition has not yet been described and pharmacological evidence has not been reported.This study aimed to identify the chemical constituents and evaluate the hypoglycemic and toxic effect of the dry extract of the E. biflora leaves (DEEB).DEEB, obtained by infusion, was analyzed using LC-HRMS and NMR, whose the catechin flavonoid was quantified using NMR. ...
Tópico(s): Ginkgo biloba and Cashew Applications
2022 - Elsevier BV | Journal of Ethnopharmacology
Produção Nacional
Revisado por pares
José Edvan Marques, Lívia Pinheiro de Queiroz, Tiago Lima de Albuquerque, Dávila Zampieri, Vânia Maria Maciel Melo, Maria Valderez Ponte Rocha,
The use of cashew apple bagasse hemicellulose hydrolysate (CABH) to produce lactic acid by two strains of lactic acid bacteria, Lactobacillus plantarum FJ05311 and L. plantarum FJ05315, was evaluated. The application of cashew apple bagasse (CAB) would enhance the establishment of a biorefinery from this agro-industrial residue since its main compounds, cellulose, hemicellulose, and lignin, can be used to obtain several bioproducts. The influence of essential parameters was studied for the production ...
Tópico(s): Ginkgo biloba and Cashew Applications
2023 - Elsevier BV | Biocatalysis and Agricultural Biotechnology
Produção Nacional
Revisado por pares
Débora Hellen Almeida de Brito, Francisco Wagner Queiroz Almeida-Neto, Lyanna Rodrigues Ribeiro, Emanuel Paula Magalhães, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio, Alice Maria Costa Martins, Paulo Nogueira Bandeira, Márcia Machado Marinho, Emmanuel Silva Marinho, Antônio C.H. Barreto, Pedro de Lima‐Neto, Gilberto D. Saraiva, Kirley Marques Canuto, Hélcio Silva dos Santos, Alexandre Magno Rodrigues Teixeira, Nágila Maria Pontes Silva Ricardo,
There is an urgent need for new inhibitors against T. cruzi, a protozoal infection that affects about 8 million people annually around the world. In this study, we describe the synthesis, characterization, and the inhibitory effects of the chalcone (E)-1-(4-aminophenyl)-3-(benzo[b]thiophen-2-yl)prop‑2-en-1-one (BNZTHP) against T. cruzi Y strain forms. The molecular structure of this compound was characterized by spectroscopic techniques, and its potential against T. cruzi was evaluated by in vitro ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2021 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Márcia Maria Mendes Marques, Selene Maia de Morais, Ana Raquel Araújo da Silva, Naiara Dutra Barroso, Tadeu Rocha Pontes Filho, Fernanda Montenegro de Carvalho Araújo, Ícaro Gusmão Pinto Vieira, Danielle Malta Lima, Maria Izabel Florindo Guedes,
Dengue represents a serious social and economic public health problem; then trying to contribute to improve its control, the objective of this research was to develop phytoterapics for dengue treatment using natural resources from Caatinga biome. Galactomannans isolated from Adenanthera pavonina L., Caesalpinia ferrea Mart., and Dimorphandra gardneriana Tull were chemically sulfated in order to evaluate the antioxidant, and antiviral activities and the role in the inhibition of virus DENV-2 in Vero ...
Tópico(s): Herbal Medicine and Trade Cooperation
2015 - Hindawi Publishing Corporation | Evidence-based Complementary and Alternative Medicine
Produção Nacional
Revisado por pares
Igor Marques Cavalcante, Natália Rodrigues de Castro Rocha, Martin E. Maier, Ana Paula Dantas de Lima, Davino M. Andrade Neto, Débora Hellen Almeida de Brito, César Liberato Petzhold, Maria Telma Gomes Freire Schanz, Nágila Maria Pontes Silva Ricardo,
A series of noncommercial polyols which do not contain β-hydrogen were used to synthesize new oleic acid based esters as potential thermally stable biolubricants. Commercial trimethylolpropane (TMP) was used to synthesize TMP trioleate as a reference polyol ester. The esters were purified by column chromatography and their structures were confirmed by 1H and 13C NMR and HRMS. The evaluated properties were kinematic viscosity, thermo-oxidative stability (by TGA) and melting point (m.p., by DSC). All ...
Tópico(s): Tribology and Wear Analysis
2014 - Elsevier BV | Industrial Crops and Products
Produção Nacional
Revisado por pares
Ana Cláudia de Souza, Sheila Cristina Ouriques Martins, Carísi Anne Polanczyk, Denizar Vianna Araújo, Ana Paula Beck da Silva Etges, Bruna Stella Zanotto, Jeruza Lavanholi Neyeloff, Leonardo Augusto Carbonera, Márcia Lorena Fagundes Chaves, João José Freitas de Carvalho, Letícia Costa Rebello, Daniel Giansante Abud, Lucas Scotta Cabral, Fabrício Oliveira Lima, F. Mont’alverne, Pedro SC Magalhães, Henrique Diegoli, Juliana Safanelli, Thales André Silveira Salvetti, Bruno de Sousa Mendes Parente, Michel Eli Frudit, Gisele Sampaio Silva, Octávio Marques Pontes‐Neto, Raul G. Nogueira,
Background The RESILIENT trial demonstrated the clinical benefit of mechanical thrombectomy in patients presenting acute ischemic stroke secondary to anterior circulation large vessel occlusion in Brazil. Aims This economic evaluation aims to assess the cost-utility of mechanical thrombectomy in the RESILIENT trial from a public healthcare perspective. Methods A cost-utility analysis was applied to compare mechanical thrombectomy plus standard medical care (n = 78) vs. standard medical care alone (n = ...
Tópico(s): Peripheral Artery Disease Management
2021 - SAGE Publishing | International Journal of Stroke