Angelo Armandi, Chiara Rosso, Aurora Nicolosi, Gian Paolo Caviglia, Maria Lorena Abate, Antonella Olivero, Daphne D’Amato, Marta Vernero, Melania Gaggini, Giorgio Maria Saracco, Davide Giuseppe Ribaldone, Jenny Lee, Amalia Gastaldelli, Elisabetta Bugianesi,
Insulin resistance plays a relevant role in the onset of non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH) and fibrosis. Irisin is an exercise-induced myokine involved in the regulation of energy homeostasis and glucose metabolism. Additionally, pre-clinical models have shown a potential role of irisin in the pathogenesis of NAFLD. The aim of this study is to explore the association between irisin, histological features and biomarkers of liver fibrogenesis ...
Tópico(s): Diet and metabolism studies
2022 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Produção Nacional
Revisado por pares
Ricardo E. da Silva, Angélica Amorim Amato, Dirce Guilhem, Marta Rodrigues de Carvalho, María Rita Carvalho Garbi Novaes,
Introduction: Although international health research involves some benefits for the host countries, such as access to innovative treatments, the research itself may not be aligned with their communities' actual health needs. Objective: To map the global landscape of clinical trials run in Latin American and Caribbean countries and discuss the addressing of local health needs in the agenda of international clinical trials. Methods: The present study is a cross-sectional overview and used data referent ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2018 - Frontiers Media | Frontiers in Pharmacology
Marten in ‘t Veld, Andrés Alástuey, Marco Pandolfi, Fúlvio Amato, Noemí Pérez, Cristina Reche, Marta Via, María Cruz Minguillón, Miguel Escudero, Xavier Querol,
In this work, time-series analyses of the chemical composition and source contributions of PM2.5 from an urban background station in Barcelona (BCN) and a rural background station in Montseny (MSY) in northeastern Spain from 2009 to 2018 were investigated and compared. A multisite positive matrix factorization analysis was used to compare the source contributions between the two stations, while the trends for both the chemical species and source contributions were studied using the Theil–Sen trend ...
Tópico(s): Air Quality Monitoring and Forecasting
2021 - Elsevier BV | The Science of The Total Environment
Teresa Moreno, Frank J. Kelly, Chrissi Dunster, Ana Oliete Dominguez, Vânia Martins, Cristina Reche, María Cruz Minguillón, Fúlvio Amato, Marta Capdevila, Eladio de Miguel, Xavier Querol,
Air quality in subway systems is of interest not only because particulate matter (PM) concentrations can be high, but also because of the peculiarly metalliferous chemical character of the particles, most of which differ radically from those of outdoor ambient air. We report on the oxidative potential (OP) of PM2.5 samples collected in the Barcelona subway system in different types of stations. The PM chemical composition of these samples showed typically high concentrations of Fe, Total Carbon, Ba, ...
Tópico(s): Air Quality Monitoring and Forecasting
2016 - Elsevier BV | Atmospheric Environment
Teresa Moreno, Vânia Martins, Xavier Querol, Timothy Peter Jones, Kelly BéruBé, María Cruz Minguillón, Fúlvio Amato, Marta Capdevila, Eladio de Miguel, Sonia Centelles, Wes Gibbons,
Most particles breathed on rail subway platforms are highly ferruginous (FePM) and extremely small (nanometric to a few microns in size). High magnification observations of particle texture and chemistry on airborne PM₁₀ samples collected from the Barcelona Metro, combined with published experimental work on particle generation by frictional sliding, allow us to propose a general model to explain the origin of most subway FePM. Particle generation occurs by mechanical wear at the brake-wheel and wheel- ...
Tópico(s): Aerosol Filtration and Electrostatic Precipitation
2014 - Elsevier BV | The Science of The Total Environment
Emilio Portaccio, Pietro Annovazzi, Angelo Ghezzi, Mauro Zaffaroni, Lucia Moiola, Vittorio Martinelli, Roberta Lanzillo, Vincenzo Brescia Morra, Francesca Rinaldi, Paolo Gallo, Carla Tortorella, Damiano Paolicelli, Carlo Pozzilli, Laura De Giglio, Paola Cavalla, Eleonora Cocco, Maria Giovanna Marrosu, Francesco Patti, Claudio Solaro, Paolo Bellantonio, Antonio Uccelli, Alice Laroni, Luisa Pastò, Marta Giannini, Maria Trojano, Gıancarlo Comı, Maria Pia Amato, Maria Pia Amato, Emilio Portaccio, Bahia Hakiki, Luisa Pastò, Marta Giannini, Lorenzo Razzolini, Isabella Righini, G. Siracusa, Angelo Ghezzi, Pietro Annovazzi, Mauro Zaffaroni, V. Martinelli, Marta Radaelli, Lucia Moiola, Gıancarlo Comı, Alessandra Protti, Emanuela Susani, R. Marazzi, Paolo Confalonieri, Valentina Torri Clerici, Paola Cavalla, Carlotta Chiavazza, Roberto Bergamaschi, Gianluigi Mancardi, Antonio Uccelli, Elisabetta Capello, Alice Laroni, Claudio Solaro, MR Tola, Luisa Caniatti, Franco Granella, Pasquale Annunziata, Katrin Plewnia, Leonello Guidi, ML Bartolozzi, Maria Rosa Mazzoni, Carlo Pozzilli, Laura De Giglio, Rocco Totaro, A Carolei, Maria Rita Rossi, Alessandra Lugaresi, Giovanna De Luca, V. Di Tommaso, Carla Tortorella, Damiano Paolicelli, Martina D’Onghia, Maria Trojano, Maria Giovanna Marrosu, Eleonora Cocco, Maurizio Melis, Francesco Patti, Cláudio Leone, Salvatore Lo Fermo, P. Bellantonio, Roberta Fantozzi, Claudio Gasperini, Alfonso Iudice, Antonio Bosco, Arianna Sartori, Roberta Lanzillo, Vincenzo Brescia Morra,
To assess fetal risk after pregnancy exposure to natalizumab in women with multiple sclerosis (MS), with a specific focus on spontaneous abortion (SA) and congenital anomalies (CA).Data of all pregnancies occurring between 2009 and 2015 in patients with MS treated with natalizumab and referring to 19 participating sites were collected and compared with those of pregnancies in untreated patients and patients treated with injectable immunomodulatory agents. Rates of SA and CA were also compared with ...
Tópico(s): Polyomavirus and related diseases
2018 - Lippincott Williams & Wilkins | Neurology
Emilio Portaccio, Lucia Moiola, Vittorio Martinelli, Pietro Annovazzi, Angelo Ghezzi, Mauro Zaffaroni, Roberta Lanzillo, Vincenzo Brescia Morra, Francesca Rinaldi, Paolo Gallo, Carla Tortorella, Damiano Paolicelli, Carlo Pozzilli, Laura De Giglio, Paola Cavalla, Eleonora Cocco, Maria Giovanna Marrosu, Claudio Solaro, Antonio Uccelli, Alice Laroni, Luisa Pastò, Marta Giannini, Maria Trojano, Giancarlo Comi, Maria Pia Amato, Maria Pia Amato, Emilio Portaccio, Bahia Hakiki, Luisa Pastò, Marta Giannini, Lorenzo Razzolini, Isabella Righini, G. Siracusa, Angelo Ghezzi, Pietro Annovazzi, Mauro Zaffaroni, V. Martinelli, Marta Radaelli, Lucia Moiola, Giancarlo Comi, Alessandra Protti, Emanuela Susani, R. Marazzi, Paolo Confalonieri, Valentina Torri Clerici, Paola Cavalla, Carlotta Chiavazza, Roberto Bergamaschi, Gianluigi Mancardi, Antonio Uccelli, Elisabetta Capello, Alice Laroni, Claudio Solaro, MR Tola, Luisa Caniatti, Franco Granella, Pasquale Annunziata, Katrin Plewnia, Leonello Guidi, ML Bartolozzi, Maria Rosa Mazzoni, Carlo Pozzilli, Laura De Giglio, Rocco Totaro, A Carolei, Maria Rita Rossi, Alessandra Lugaresi, Giovanna De Luca, V. Di Tommaso, Carla Tortorella, Damiano Paolicelli, Martina D’Onghia, Maria Trojano, Maria Giovanna Marrosu, Eleonora Cocco, Maurizio Melis, Francesco Patti, Cláudio Leone, Salvatore Lo Fermo, P. Bellantonio, Roberta Fantozzi, Claudio Gasperini, Alfonso Iudice, Antonio Bosco, Arianna Sartori, Roberta Lanzillo, Vincenzo Brescia Morra,
Objective To assess the risk of disease reactivation during pregnancy after natalizumab suspension in women with multiple sclerosis (MS). Methods Data of all pregnancies occurring between 2009 and 2015 in patients with MS treated with natalizumab and referring to 19 participating sites were collected and compared with those of pregnancies in untreated patients and patients treated with injectable immunomodulatory agents through a 2-factor repeated measures analysis. Predictors of disease activity were assessed ...
Tópico(s): Pregnancy and Medication Impact
2018 - Lippincott Williams & Wilkins | Neurology
Claudio Solaro, C. Rezzani, E. Trabucco, Maria Pia Amato, Valentina Zipoli, Emilio Portaccio, Marta Giannini, Francesco Patti, Emanuele D’Amico, Jessica Frau, Lorena Lorefice, Simona Bonavita, Michele Della Corte, Maria Grazia Grasso, L. Finamore, Angelo Ghezzi, Pietro Annovazzi, Mariarosa Rottoli, Claudio Gasperini, Domenico A. Restivo, Davide Maimone, Paolo Rossi, ML Stromillo, Roberto Bergamaschi,
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) with a chronic course. Dysphagia represents one of the current challenges in clinical practice for the management of MS patients. Dysphagia starts to appear in mildly impaired MS subjects (EDSS 2-3) and becomes increasingly common in the most severely disabled subjects (EDSS 8-9). The aim of the present study was to evaluate the frequency and characteristics of patient-reported dysphagia in MS patients with a multicenter ...
Tópico(s): Polyomavirus and related diseases
2013 - Elsevier BV | Journal of the Neurological Sciences
Ermelinda De Meo, Massimo Filippi, Maria Trojano, Gıancarlo Comı, Francesco Patti, Vincenzo Brescia Morra, Giuseppe Salemi, Marco Onofrj, Giacomo Lus, Eleonora Cocco, Mattia Fonderico, Valentina Torri Clerici, Giorgia Teresa Maniscalco, Paola Valentino, Antonio Bertolotto, Alessandra Lugaresi, Roberto Bergamaschi, Marco Rovaris, Patrizia Sola, Gioacchino Tedeschi, Ilaria Pesci, Umberto Aguglia, Paola Cavalla, Davide Maimone, Franco Granella, Marika Vianello, Marta Simone, Emilio Portaccio, Maria Pia Amato,
This study was undertaken to describe and compare disease course and prognosis of early (ie, disease onset before age 11 years) and late (ie, disease onset after age 11 years) onset pediatric multiple sclerosis.Prospectively collected clinical information from Italian Multiple Sclerosis Register of 1993 pediatric multiple sclerosis patients, of whom 172 had early onset, was analyzed. Cox models adjusted for sex, baseline Expanded Disability Status Scale score, and disease-modifying treatments and ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2022 - Wiley | Annals of Neurology
Mariana Branco, Luís Ruano, Emilio Portaccio, Benedetta Goretti, Claudia Niccolai, Francesco Patti, Clara Grazia Chisari, Paolo Gallo, Paola Grossi, Angelo Ghezzi, Marco Roscio, Flavia Mattioli, Fabio Bellomi, Marta Simone, Rosa Gemma Viterbo, Maria Pia Amato,
Tópico(s): Neurological Disease Mechanisms and Treatments
2019 - Springer Science+Business Media | Neurological Sciences
Luís Ruano, Mariana Branco, Emilio Portaccio, Benedetta Goretti, Claudia Niccolai, Francesco Patti, Clara Grazia Chisari, Paolo Gallo, Paola Grossi, Angelo Ghezzi, Marco Roscio, Flavia Mattioli, Chiara Stampatori, Marta Simone, Rosa Gemma Viterbo, Maria Pia Amato,
Background: Patients with paediatric-onset multiple sclerosis (POMS) could be at an increased risk for cognitive impairment (CI), given the potential harmful effects of disease activity in neurodevelopment. However, there is scarce information on their long-term cognitive outcomes. Objective: To compare the prevalence and profile of CI between adults with a history of POMS and those with classic, adult-onset multiple sclerosis (AOMS). Methods: Cognitive performance was assessed through the Brief Repeatable ...
Tópico(s): Multiple Sclerosis Research Studies
2017 - SAGE Publishing | Multiple Sclerosis Journal
Produção Nacional
Revisado por pares
Ana Marli Christovam Sartori, Maria Aparecida Shikanai‐Yasuda, Vicente Amato Neto, Marta Heloísa Lopes,
A series of 18 patients with chronic Chagas' disease and human immunodeficiency virus infection were followed up for 2 to 66 months (median, 15.5 months). Artificial xenodiagnosis was positive for 81.3% and natural xenodiagnosis was positive for 81.8% of patients for whom they were performed; 81.8% of 11 patients had medium- or high-level parasitemia. Reactivation of Chagas' disease--direct microscopic examination of blood revealing parasites and, clinically, patients presenting with cardiac disease-- ...
Tópico(s): Viral Infections and Immunology Research
1998 - Oxford University Press | Clinical Infectious Diseases
Maria Pia Amato, Valentina Saia, Bahia Hakiki, Marta Giannini, Luisa Pastò, S Zecchino, S. Lori, Emilio Portaccio, Marinella Marinoni,
Objective: Chronic cerebrospinal venous insufficiency (CCSVI) was hypothesized to play a causative role in multiple sclerosis (MS). The assessment of pediatric-onset MS (POMS) may provide a unique window of opportunity to study hypothesized risk factors in close temporal association with the onset of the disease. Methods: Internal jugular veins, vertebral veins and intracranial veins were evaluated with extracranial and intracranial ultrasound in 15 POMS and 16 healthy controls. Assessor’s blinding ...
Tópico(s): Vestibular and auditory disorders
2012 - SAGE Publishing | Multiple Sclerosis Journal
Fulvio Braido, Giovanni Melioli, Mario Cazzola, Leonardo M. Fabbri, Francesco Blasi, Lorenzo Moretta, Giorgio Walter Canonica, Valentina Garelli, Diego Bagnasco, Barbara Maria Colombo, Chiara Lagasio, Andrea Segreti, Marcello Basili, Meridiana Dodaj, Arnaldo Alessandrini, Sara Maggi, Marinella Rossi, Marco Bighiani, Sabrina Rocca, Vittorio Cardaci, Ilaria Pedicelli, Francesca Mattei, Marta Censori, Valentina Dall'Armi, Massimiliano Appodia, Luisa Maria Lapenna, Michela Bisceglia, Stefano Centanni, Roberta Barlassina, Massimo Verga, Angelo Guido Corsico, Amelia Grosso, Erica Gini, Federica Albicini, Eti Maria Giulia Di Vincenzo, Marta Agnesi, Gennaro D’Amato, Antonello Salzillo, Amedeo Piccolo, Claudio Damonte, Barbara Miragoli, Alberto Passera, Paolo Roveda, Giuseppe La Vecchia, Maria Mercuri, Alberto Scala, Mauro Ferliga, Giovanni Gardini Gardenghi, Luigi Taranto, A. Meriggi, E Gatto, Paolo Noschese, Gaetano Magro, Alberto Pesci, Francesco Tana, Valentina Paolini, Italo Stefani, Marco Trigiani, Milena Maffini, P Contini,
Polyvalent mechanical bacterial lysates (PMBLs) have been shown to reduce the number of infectious episodes in patients with recurrent infections of the respiratory tract. Some previous investigations have also shown the effectiveness of PMBLs in reducing exacerbations of chronic obstructive pulmonary disease (COPD). The AIACE study, which was developed according to criteria of evidence-based medicine, evaluated whether the administration of PMBLs to COPD patients, in addition to the recommended treatment, ...
Tópico(s): Respiratory and Cough-Related Research
2015 - Elsevier BV | Pulmonary Pharmacology & Therapeutics
Produção Nacional
Revisado por pares
Claudio A. Belis, Federico Karagulian, Fúlvio Amato, Susana Marta Almeida, Paulo Artaxo, David C. S. Beddows, Vera Bernardoni, Maria Chiara Bove, Samara Carbone, Daniela Cesari, Daniele Contini, E. Cuccia, Evangelia Diapouli, Konstantinos Eleftheriadis, Olivier Favez, Imad El Haddad, Roy M. Harrison, Stig Hellebust, Jan Hovorka, Eunhwa Jang, Héctor Jorquera, T. Kammermeier, Matthias Karl, F. Lucarelli, Dennis Mooibroek, S. Nava, Jacob Klenø Nøjgaard, Pentti Paatero, Marco Pandolfi, Maria Grazia Perrone, Jean‐Eudes Petit, Adriana Pietrodangelo, Petra Pokorná, P. Prati, Andrê S. H. Prévôt, Ulrich Quaß, Xavier Querol, Dikaia Saraga, Jean Sciare, Athanasios Sfetsos, G. Valli, R. Vecchi, Mika Vestenius, Eduardo Yubero, Philip K. Hopke,
The performance and the uncertainty of receptor models (RMs) were assessed in intercomparison exercises employing real-world and synthetic input datasets. To that end, the results obtained by different practitioners using ten different RMs were compared with a reference. In order to explain the differences in the performances and uncertainties of the different approaches, the apportioned mass, the number of sources, the chemical profiles, the contribution-to-species and the time trends of the sources ...
Tópico(s): Air Quality and Health Impacts
2015 - Elsevier BV | Atmospheric Environment
Anna Zolin, Ettore Amato, Marta D’Auria, María Gori, Pol Huedo, Anna Bossi, M. Pontello,
SUMMARY The annual incidence of listeriosis in Italy is lower (0·19–0·27 per 100 000 inhabitants per year) than in Europe (0·34–0·52 per 100 000 inhabitants per year). Since the observed incidence of listeriosis may be biased downward for underdiagnosis or under-reporting, this work aims to estimate the real incidence of listeriosis during a 9-year period in the Lombardy region, Italy. Data on listeriosis cases were collected from national mandatory notification system (MAINF) and Laboratory-based ...
Tópico(s): Listeria monocytogenes in Food Safety
2017 - Cambridge University Press | Epidemiology and Infection
Fulvio Braido, Ilaria Baiardini, Pietro Alleri, Elena Bacci, Carlo Barbetta, Michela Bellocchia, Alida Benfante, Francesco Blasi, Caterina Bucca, Maria Teresa Busceti, Stefano Centanni, Maria Cristina Colanardi, Marco Contoli, Angelo Guido Corsico, Maria D’Amato, Fabiano Di Marco, Dottorini Marco, Marta Ferrari, Giovanni Florio, Alessandro G. Fois, Maria Pia Foschino Barbaro, Silvia Garuti, Giuseppe Girbino, Amelia Grosso, Manuela Latorre, Sara Maniscalco, Francesco Mazza, Carlo Mereu, Giorgia Molinengo, Josuel Ora, Pierluigi Paggiaro, Vincenzo Patella, Girolamo Pelaia, Pietro Pirina, Alfio Proietto, Paola Rogliani, Pierachille Santus, Nicola Scichilone, Francesca Simioli, Paolo Solidoro, Silvia Terraneo, Umberto Zuccon, Giorgio Walter Canonica,
Asthma considerably impairs patients' quality of life and increases healthcare costs. Severity, morbidity, and degree of disease control are the major drivers of its clinical and economic impact. National scientific societies are required to monitor the application of international guidelines and to adopt strategies to improve disease control and better allocate resources.to provide a detailed picture of the characteristics of asthma patients and modalities of asthma management by specialists in ...
Tópico(s): Inhalation and Respiratory Drug Delivery
2017 - Elsevier BV | Pulmonary Pharmacology & Therapeutics
Produção Nacional
Revisado por pares
Vicente Amato Neto, Marta Heloísa Lopes, Cláudia Regina De Marchi, Maria de Fátima dos Santos Silva,
Valorizando a sensibilidade do sistema Quantitative Buffy Coat (QBC), documentada em modelo experimental murino, estando os animais com infecção aguda pelo Trypanosoma cruzi houve tentativa de evidenciar esse parasita no sangue periférico de 100 pacientes com doença de Chagas, em fase crônica. Com o emprego desse método, nenhuma positividade ocorreu, evidentemente em virtude das pequenas parasitemias, não reveláveis pela técnica, pelo menos conforme o verificado através da casuística considerada.
Tópico(s): Science and Education Research
1998 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Vânia Martins, Teresa Moreno, María Cruz Minguillón, Fúlvio Amato, Eladio de Miguel, Marta Capdevila, Xavier Querol,
The Barcelona subway system comprises eight subway lines, at different depths, with different tunnel dimensions, station designs and train frequencies. An extensive measurement campaign was performed in this subway system in order to characterise the airborne particulate matter (PM) measuring its concentration and investigating its variability, both inside trains and on platforms, in two different seasonal periods (warmer and colder), to better understand the main factors controlling it, and therefore ...
Tópico(s): Air Quality Monitoring and Forecasting
2015 - Elsevier BV | The Science of The Total Environment
Teresa Moreno, Noemí Pérez, Cristina Reche, Vânia Martins, Eladio de Miguel, Marta Capdevila, Sonia Centelles, María Cruz Minguillón, Fúlvio Amato, Andrés Alástuey, Xavier Querol, W. Gibbons,
A high resolution air quality monitoring campaign (PM, CO2 and CO) was conducted on differently designed station platforms in the Barcelona subway system under: (a) normal forced tunnel ventilation, and (b) with daytime tunnel ventilation systems shut down. PM concentrations are highly variable (6–128 μgPM1 m−3, 16–314 μgPM3 m−3, and 33–332 μgPM10 m−3, 15-min averages) depending on ventilation conditions and station design. Narrow platforms served by single-track tunnels are heavily dependent on forced ...
Tópico(s): Air Quality Monitoring and Forecasting
2014 - Elsevier BV | Atmospheric Environment
Bahia Hakiki, Emilio Portaccio, Marta Giannini, Lorenzo Razzolini, Luisa Pastò, Maria Pia Amato,
The objective of this article is to report our experience on fingolimod suspension in multiple sclerosis patients. We evaluated clinical and magnetic resonance (MR) outcomes in six patients after fingolimod discontinuation. Within three months from fingolimod suspension, five subjects returned to pre-treatment disease activity; one patient, however, exhibited a clear rebound of clinical and MR activity. Our findings suggest that clinical and MR outcomes after fingolimod suspension can vary among ...
Tópico(s): Peripheral Neuropathies and Disorders
2012 - SAGE Publishing | Multiple Sclerosis Journal
Emilio Portaccio, Benedetta Goretti, Valentina Zipoli, Bahia Hakiki, Marta Giannini, Luisa Pastò, Lorenzo Razzolini, Maria Pia Amato,
Tópico(s): Long-Term Effects of COVID-19
2010 - Springer Science+Business Media | Neurological Sciences
S. Lori, Emilio Portaccio, Valentina Zipoli, Marta Giannini, Serena Scarpelli, Benedetta Goretti, Maria Pia Amato,
Tópico(s): Hearing, Cochlea, Tinnitus, Genetics
2011 - Springer Science+Business Media | Neurological Sciences
Roberto Ferrarese, Raffaella Alessia Zuppardo, Marta Puzzono, Alessandro Mannucci, Virginia Amato, Ilaria Ditonno, Maria Grazia Patricelli, Annalisa Russo Raucci, Massimo Clementi, Ugo Elmore, Riccardo Rosati, Pier Alberto Testoni, Nicasio Mancini, Giulia Martina Cavestro,
The role of microbiota in Lynch syndrome (LS) is still under debate. We compared oral and fecal microbiota of LS saliva and stool samples with normal healthy controls (NHC).Total DNA was purified from feces and saliva to amplify the V3-V4 region of the 16s rRNA gene. Sequences with a high-quality score and length >250 bp were used for taxonomic analysis with QIIME software.Compared to NHC, LS fecal samples demonstrated a statistically significant increase of Bacteroidetes and Proteobacteria and a significant ...
Tópico(s): Cancer-related molecular mechanisms research
2020 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Valentina Zipoli, Bahia Hakiki, Emilio Portaccio, Francesco Lolli, G. Siracusa, Marta Giannini, Leonardo Pantoni, Francesca Pescini, Sandro Sorbi, Maria Pia Amato,
Background McDonald Criteria (MDC) have been validated in selected patients at high risk for multiple sclerosis (MS). However, possible overdiagnosis of MS can represent critical issues in less controlled clinical settings. Objective To assess the contribution of oligoclonal bands (OB) to MS diagnosis in current clinical practice. Methods We included all the patients admitted to our Department since 2001 who had undergone diagnostic workup for a possible MS diagnosis, followed up for at least 1 year. ...
Tópico(s): Polyomavirus and related diseases
2009 - SAGE Publishing | Multiple Sclerosis Journal
Isabel Portillo, Eunate Arana‐Arri, Iñaki Gutiérrez‐Ibarluzea, Isabel Bilbao, José Luis Hurtado, Cristina Sarasqueta, Isabel Idígoras, Luís Bujanda, José Luis Hurtado, Carmen de No, Carlos Enciso, Maite Escalante, Luis Francisco Eraña, Begoña Atarés, José Javier Aguirre, Esther Pereda, Edurne Marañón, Pedro Otazua, María Fernández-Abad, Jose Francisco Egido, Eva Zapata, Leire Zubiaurre‐Elorza, Juana Mari Rodriguez, Pedro Esteban Sampedro, Marisa Goyeneche, J. M. Arrinda, M. Gomez, Management Mari Luz Jauregui, Marta Gómez, Marta Sáiz, Rafael Rotaeche del Campo, María A. Gutiérrez-Stampa, Vanessa Aguilar‐Gama, Luís Bujanda, Inês Gil, Jesús M. Bañales, María J. Perugorria, Mauro D’Amato, Cristina Sarasqueta, Marta Herreros‐Villanueva, Marian Gutiérrez-Stampa, Vanessa Aguilar‐Gama, Isabel Montalvo, Jose Miguel Larzabal, Maddi Garmendia, Fernando Izquierdo, Javier Fernández, Iago Rodriguez, Alaín Huerta, Eduardo de Miguel, Inmaculada Barredo, Fidencio Bao, Anaiansi Hernández, Isabel Rodríguez, J.J. Martínez Fernández, Maria Imaz, Ángel Calderón, Francisco Polo, Nagore Arbide, Gaspar Lantarón, Cristina Quesada, C. A. Vidurrizaga-De Amezaga, Itziar Marzana, E Ojembarrena, Haritz Cortés, Iñaki Casado, Mar Ramirez, Amaia Aperribay, Ignacio López, Lorea Martínez‐Indart, Marta Estalella, Ignacio Pijoan, Marta de la Cruz, J. Bidaurrazaga, Nerea Muniozguren, Nerea Larrañaga, Covadonga Audicana, Isabel Bilbao, J. L. Bilbao, Eduardo Millán, S. Unanue-Arza, Nere Mendizabal,
The overall aim of this study was to describe trends in participation rates and detection of lesions in a colorectal cancer (CRC) screening programme, during three rounds, using faecal immunochemical test (FIT). National registers were used to collect data on invitations for CRC screening in the Basque Country (Spain) from 2009 to 2014. Information about participation, age, gender and lesions in each round were collected. A total of 961.533 individuals were included in the analysis; respectively, 584. ...
Tópico(s): Gastric Cancer Management and Outcomes
2018 - Oxford University Press | European Journal of Public Health
Maria Grazia Zizzo, Michelangelo Auteri, Antonella Amato, G Caldara, Domenico Nuzzo, Marta Di Carlo, Rosa Serio,
Abstract Background Angiotensin II (Ang II), the main peptide of the renin‐angiotensin system ( RAS ), has been suggested to be involved in inflammatory bowel diseases. Since RAS has emerged as gut motility regulator, and dysmotility is associated with intestinal inflammation, our objective was to investigate in rat 2,4‐dinitrobenzenesulfonic acid ( DNBS )‐induced colitis the functionality of RAS and its contribution to colonic motor alterations. Methods The effects of Ang II on the longitudinal colonic muscular ...
Tópico(s): Receptor Mechanisms and Signaling
2017 - Wiley | Neurogastroenterology & Motility
Emilio Portaccio, Angelo Ghezzi, Bahia Hakiki, Andrea Sturchio, Vittorio Martinelli, Lucia Moiola, Francesco Patti, Gianluigi Mancardi, Claudio Solaro, M. R. Tola, Carlo Pozzilli, Laura De Giglio, Rocco Totaro, Alessandra Lugaresi, Giovanna De Luca, Damiano Paolicelli, Maria Giovanna Marrosu, Gıancarlo Comı, Maria Trojano, Maria Pia Amato, Maria Pia Amato, Emilio Portaccio, Bahia Hakiki, Andrea Sturchio, Luisa Pastò, Marta Giannini, Lorenzo Razzolini, E. Piscolla, G. Siracusa, Angelo Ghezzi, A. Rizzo, Mauro Zaffaroni, Vittorio Martinelli, Marta Radaelli, Lucia Moiola, Gıancarlo Comı, Alessandra Protti, C. Spreafico, R. Marazzi, Paola Cavalla, Silvia Masera, Roberto Bergamaschi, Gianluigi Mancardi, Elisabetta Capello, Claudio Solaro, M. R. Tola, Luisa Caniatti, Franco Granella, Paolo Immovilli, Pasquale Annunziata, Lorenzo De Santi, Katrin Plewnia, Leonello Guidi, M. Bartolozzi, Maria Rosa Mazzoni, Carlo Pozzilli, Laura De Giglio, Rocco Totaro, A Carolei, Mariateresa Rossi, Alessandra Lugaresi, Giovanna De Luca, V. Di Tommaso, Maria Trojano, Damiano Paolicelli, Alessandro Carrozzo, Martina D’Onghia, Maria Giovanna Marrosu, Luigina Musu, Francesco Patti, L. Carmela, Salvatore Lo Fermo,
Objective To assess relapses, disability progression and the role of disease modifying drugs (DMDs) in the year after delivery in women with multiple sclerosis (MS). Methods We prospectively followed-up pregnancies occurring between 2002 and 2008 in women with MS, recruited from 21 Italian MS centres. The risk of relapses and disability progression in the year after delivery was assessed using time-dependent Cox regression analysis. Results 350 out of 423 pregnancies were assessed (pregnancies not resulting ...
Tópico(s): Pregnancy and Medication Impact
2014 - BMJ | Journal of Neurology Neurosurgery & Psychiatry
Maria Pia Amato, Emilio Portaccio, Benedetta Goretti, Valentina Zipoli, Bahia Hakiki, Marta Giannini, Luisa Pastò, Lorenzo Razzolini,
Tópico(s): Rheumatoid Arthritis Research and Therapies
2010 - Springer Science+Business Media | Neurological Sciences
Luca Negri, Sabina Cilia, Monica Falautano, Monica Grobberio, Claudia Niccolai, Marianna Pattini, Erika Pietrolongo, Maria Esmeralda Quartuccio, Rosa Gemma Viterbo, Beatrice Allegri, Maria Pia Amato, Miriam Benin, Giovanna De Luca, Claudio Gasperini, Eleonora Minacapelli, Francesco Patti, Maria Trojano, Marta Bassi,
Health professionals caring for persons with multiple sclerosis (MS) are faced with increasingly complex working conditions that can undermine their job satisfaction and the quality of their healthcare services. The aim of this study was to delve into health professionals' job satisfaction by assessing the predictive role of happiness and meaning at work. Specifically, it was hypothesized that job meaning would moderate the relationship between job happiness and satisfaction.The study hypothesis ...
Tópico(s): Workaholism, burnout, and well-being
2021 - Springer Science+Business Media | Neurological Sciences