... there anything wrong with the Systeme Nouveau? (by Mendonca, Marta) 12. 9. Quantification of natural and positive laws: ...
Tópico(s): Classical Philosophy and Thought
2010 - John Benjamins Publishing Company | Controversies
Gaëlle Marteil, Adán Guerrero, André Filipe Vieira, Bernardo P. de Almeida, Pedro Machado, Susana Mendonça, Marta Mesquita, Beth Villarreal, Irina Fonseca, María E. Francia, Katharina Dores, Nuno Pimpão Martins, Swadhin Chandra Jana, Erin M. Tranfield, Nuno L. Barbosa‐Morais, Joana Paredes, David Pellman, Susana A. Godinho, Mónica Bettencourt‐Dias,
Abstract Centrosomes are the major microtubule organising centres of animal cells. Deregulation in their number occurs in cancer and was shown to trigger tumorigenesis in mice. However, the incidence, consequence and origins of this abnormality are poorly understood. Here, we screened the NCI-60 panel of human cancer cell lines to systematically analyse centriole number and structure. Our screen shows that centriole amplification is widespread in cancer cell lines and highly prevalent in aggressive ...
Tópico(s): Cancer-related Molecular Pathways
2018 - Nature Portfolio | Nature Communications
Sı́lvia Chaves, Ratomir Jelić, Catarina Mendonça, Marta P. Carrasco, Yutaka Yoshikawa, Hiromu Sakurai, M. Amélia Santos,
The development of metal-containing pharmaceuticals as insulin-mimetics has been the object of recent worldwide research. We have examined a series of zinc(ii) and molybdenum(vi) complexes with model O,S-donor ligands (thiomaltol and 1,2-dimethyl-3-hydroxypyridine-4-thione (DMHTP)) and the corresponding O,O-analogues (maltol and DMHP) for their insulin-mimetic activity. Aimed at getting structure-activity relationships, some physical-chemical properties were also studied, such as metal-complex formation, ...
Tópico(s): Free Radicals and Antioxidants
2009 - Oxford University Press | Metallomics
Constança Pomba, Nuno Mendonça, Marta Costa, Deolinda Louro, Bruno Baptista, Mónica S. Ventura Ferreira, José Duarte Correia, Manuela Caniça,
We developed 2 variants, A and B, of a multiplex polymerase chain reaction method for detecting the beta-lactam resistance genes bla(TEM), bla(SHV), and bla(OXA) in 122 uropathogenic Escherichia coli animal strains. Method B yielded 98% specificity and 100% sensitivity, and method A yielded 100% and 89%, respectively. Variant B was more accurate (99%) than A (94%).
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2006 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Catarina Mendonça, Marta Oliveira, Liliana Fontes, Jorge A. Santos,
Walking to a pacing stimulus has proven useful in motor rehabilitation, and it has been suggested that spontaneous synchronization could be preferable to intentional synchronization. But it is still unclear if the paced walking effect can occur spontaneously, or if intentionality plays a role. The aim of this work is to analyze the effect of sound pacing on gait with and without instruction to synchronize, and with different rhythmic auditory cues, while walking on a treadmill. Firstly, the baseline ...
Tópico(s): Action Observation and Synchronization
2014 - Elsevier BV | Human Movement Science
Catarina Vinagre, Diana Madeira, Vanessa Mendonça, Marta Dias, Joana Roma, Mário Diniz,
Tópico(s): Aquaculture Nutrition and Growth
2014 - Elsevier BV | Marine Environmental Research
Catarina Vinagre, Diana Madeira, Vanessa Mendonça, Marta Dias, Joana Roma, Mário Diniz,
Various studies in captivity and in the wild have pointed to the effect of season, and temperature in particular, in the levels of the oxidative stress biomarkers currently used for environmental quality assessment. However, knowledge on how temperature affects the oxidative stress response is unavailable for most species. This study investigated the effect of increasing temperature on lipid peroxidation, catalase activity, superoxide dismutase and glutathione-S-transferase in the shrimps, Palaemon ...
Tópico(s): Aquaculture Nutrition and Growth
2014 - Elsevier BV | Journal of Thermal Biology
Rute Mendonça, Marta C. Soares, Redouan Bshary, Rui F. Oliveira,
The nonapeptide arginine vasotocin (AVT) and its mammalian homologue arginine vasopressin are well known for their role in the modulation of several intraspecific social behaviours, such as social approach/withdrawal and aggression. Recently, we suggested that AVT might also be important in the regulation of interspecific social behaviours as it modulates interspecific cooperative behaviours in the Indo-Pacific bluestreak cleaner wrasse <i>Labroides dimidiatus.</i> AVT injections decreased ...
Tópico(s): Animal Behavior and Reproduction
2013 - Karger Publishers | Brain Behavior and Evolution
Joana Sousa Ribeiro, Cláudia Conceição, Joel Pereira, Cláudia Leone, Pedro Mendonça, Marta Temido, Carlota Pacheco Vieira, Gilles Dussault,
The mobility of health professionals in the European Union is a phenomenon which policy-makers must take into account to provide the conditions to adjust for demand and supply of health services. This paper presents the case of Portugal, a country which at the same time imports and exports health workers. Since the early 1990s Portugal became a destination country receiving foreign health care professionals. This situation is now changing with the current economic situation as fewer immigrants come ...
Tópico(s): Employment and Welfare Studies
2013 - Elsevier BV | Health Policy
Diana Madeira, Vanessa Mendonça, Marta Dias, Joana Roma, Pedro M. Costa, Miguel Larguinho, Catarina Vinagre, Mário Diniz,
The ability to cope with high temperature variations is a critical factor in intertidal communities. Two species of intertidal rocky shore shrimps (Palaemon sp.) with different vertical distributions were collected from the Portuguese coast in order to test if they were differentially sensitive to thermal stress. Three distinct levels of biological organization (organismal, biochemical, and cellular) were surveyed. The shrimp were exposed to a constant rate of temperature increase of 1 °C.h− 1, starting ...
Tópico(s): Invertebrate Immune Response Mechanisms
2015 - Elsevier BV | Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
Produção Nacional
Revisado por pares
Dilton Rodrigues Mendonça, Marta Silva Menezes, Marcos Almeida Matos, Daniel Santos Rebouças, Jucelino Nery da Conceição Filho, Reginara Souza de Assis, Leila Carneiro,
Acute poisoning is a frequent accident in childhood, particularly in children under 4 years of age. This was a descriptive study with data collected from standardized forms of the Poison Control Center and patient record charts. All the cases of acute poisoning in children aged 0 to 14 years during the period 2008 to 2012 were selected. The variables studied comprised characteristics of the events and toxic agents, clinical development, and outcome. A total of 657 cases of acute poisoning, with ...
Tópico(s): Restraint-Related Deaths
2016 - SAGE Publishing | Global Pediatric Health
Amanda Justino, Duarte Vieira Henrique, Simone Mendonça Freitas Marta,
The objective of this work was to study combinations of high doses of boron (B) and zinc (Zn) in the recoating of perennial soybean seeds, in order to provide these nutrients to the future plants. The physical, physiological and nutritional characteristics of the coated seeds and initial development of plants in a greenhouse were evaluated. Tests carried out in the laboratory were conducted in a completely randomized design, and the experiments completed in a greenhouse were a randomized block design. ...
Tópico(s): Agricultural Science and Fertilization
2016 - Academic Journals | AFRICAN JOURNAL OF BIOTECHNOLOGY
Produção Nacional
Revisado por pares
Gabrielle Ribeiro de Andrade, Roger New, Osvaldo A. Sant’Anna, Neil Williams, Rosely Cabette Barbosa Alves, Daniel C. Pimenta, Hugo Vigerelli, Bruna Melo, Letícia B. Rocha, Roxane Maria Fontes Piazza, Lúcia Mendonça‐Previato, Marta de Oliveira Domingos,
E. coli O111 strains are responsible for outbreaks of blood diarrhea and hemolytic uremic syndrome throughout the world. Because of their phenotypic variability, the development of a vaccine against these strains which targets an antigen that is common to all of them is quite a challenge. Previous results have indicated, however, that O111 LPS is such a candidate, but its toxicity makes LPS forbidden for human use. To overcome this problem, O111 polysaccharides were conjugated either to cytochrome ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2014 - Taylor & Francis | Human Vaccines & Immunotherapeutics
Rui Cereja, Vanessa Mendonça, Marta Dias, Catarina Vinagre, Fátima Gil, Mário Diniz,
Currently, the effects of global warming on marine organisms are widely recognized by the scientific community. However, studies that relate the increase in ocean temperature with other stress factors are still scarce. The main aim of this study was to evaluate the effects of water temperature increase on the parasite Anilocra frontalis, the parasite's effects over its host Pomatoschistus microps. Therefore, P. microps were subjected to A. frontalis parasitization and both species were then exposed ...
Tópico(s): Physiological and biochemical adaptations
2018 - Elsevier BV | Ecological Indicators
Produção Nacional
Revisado por pares
Carla Verônica Corrêa, Aline Mendes de Sousa Gouveia, Bruno Novaes Menezes Martins, Letícia Galhardo Jorge, Natália de Brito Lima Lanna, Ana Emília Barbosa Tavares, Veridiana Zocoler de Mendonça, Regina Marta Evangelista,
The current study aimed to evaluate the influence of six ripening stages on physicochemical characteristics of acerola fruits from cultivar Olivier. The fruits were obtained at Experimental Orchard of the Sao Paulo State University. The experimental design was completely randomized, with six ripening staged and four replications. The physicochemical characteristics evaluated were pH, soluble solids, titratable acidity, ratio, ascorbic acid (vitamin C), reducing sugars, total sugars, sucrose and colour. ...
Tópico(s): Healthcare Regulation
2017 - Sociedade de Ciências Agrárias de Portugal | Revista de Ciências Agrárias
Diana Madeira, Vanessa Mendonça, Marta Dias, Joana Roma, Pedro M. Costa, Mário Diniz, Catarina Vinagre,
The intertidal habitat is characterized by environmental conditions with steep gradients. Thus, inhabiting communities have long served as models in stress research. Moreover, several studies have reported their vulnerability to climate change and consequent distribution shifts (up to 50 km per decade) and abundance changes. The aims of this study were to test the effects of temperature on the rock goby Gobius paganellus in order to understand its resistance to environmental fluctuations (e.g. low ...
Tópico(s): Neurobiology and Insect Physiology Research
2014 - Elsevier BV | Ecological Indicators
Produção Nacional
Revisado por pares
Ana Paula Hvenegaard, Angélica de Mendonça Vaz Safatle, Marta Guimarães, Antônio José Piantino Ferreira, Paulo S.M. Barros,
A retrospective study was conducted to identify the occurrence and types of ocular disorders in 57 Amazon parrots admitted to the Ophthalmology Service, Veterinary Teaching Hospital, School of Veterinary Medicine, University of São Paulo, Brazil from 1997 to 2006. The most frequent observed disorder was cataracts, present in 24 of the 114 examined eyes (57 parrots). Uveitis, ulcerative keratitis and keratoconjunctivitis were frequently diagnosed as well. The cornea was the most affected ocular structure, ...
Tópico(s): Venomous Animal Envenomation and Studies
2009 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira
Produção Nacional
Revisado por pares
Alex Lopes da Silva, Edênio Detmann, Luciana Navajás Rennó, Alexandre Mendonça Pedroso, Marta M.S. Fontes, Valber C. L. Morais, Anna Luiza Lacerda Sguizzato, Marcelo B. Abreu, Polyana Pizzi Rotta, Marcos Inácio Marcondes,
The aim of this work was to evaluate the influence of increasing amounts of rumen undegradable protein (RUP) on intake, nutrient digestibility, rumen kinetics and fermentation characteristics and N use efficiency of dairy Holstein heifers. Eight rumen-cannulated Holstein heifers (initial body weight 276 ± 8.3 kg) were used in a replicate 4 × 4 Latin square design with four dietary RUP amounts in the total dietary protein, as follows: 38% of RUP (38RUP), 44% of RUP (44RUP), 51% of RUP (51RUP) and 57% of RUP ( ...
Tópico(s): Animal health and immunology
2018 - Elsevier BV | Animal Feed Science and Technology
Produção Nacional
Revisado por pares
Edílson Martins Rodrigues Neto, Lídia Audrey Rocha Valadas, Patrícia Leal Dantas Lobo, Said Gonçalves da Cruz Fonseca, Francisco Vagnaldo Fechine, Mara Assef Leitão Lotif, Mary Anne Medeiros Bandeira, Julia Fontinele Mendonça, Karianne Marques de Mendonça, Marta Maria de França Fonteles,
Dental caries is a sugar-dependent condition common in childhood, which causes microbiological imbalance in dental biofilm. The present study evaluated the antimicrobial efficacy of a 2.5% Brazilian Red Propolis (BRP) dental varnish to prevent caries in children. Seventy-five children with high caries risk, aged between 36 and 71 months and with no caries, were assigned to three groups to receive varnish treatment containing 2.5% BRP, 1% chlorhexidine, or 5% fluoride. The varnish was applied to the ...
Tópico(s): Heavy Metals in Plants
2021 - Hindawi Publishing Corporation | Evidence-based Complementary and Alternative Medicine
Produção Nacional
Revisado por pares
Thayná Mendonça Avelino, Marta García‐Arévalo, Felipe Rafael Torres, Marieli M. G. Dias, Romênia R. Domingues, Murilo de Carvalho, Matheus de Castro Fonseca, Vanessa Kiraly Thomaz Rodrigues, Adriana Franco Paes Leme, Ana Carolina Migliorini Figueira,
Worldwide obesity, defined as abnormal or excessive fat accumulation that may result in different comorbidities, is considered a pandemic condition that has nearly tripled in the last 45 years. Most studies on obesity use animal models or adipocyte monolayer cell culture to investigate adipose tissue. However, besides monolayer cell culture approaches do not fully recapitulate the physiology of living organisms, there is a growing need to reduce or replace animals in research. In this context, the ...
Tópico(s): Genetics, Aging, and Longevity in Model Organisms
2022 - Elsevier BV | SLAS DISCOVERY
Produção Nacional
Revisado por pares
Natasha Mendonça Quintino, Marta Helena Souza De Conti, Roger Palma, Márcia Aparecida Nuevo Gatti, Sandra Fiorelli Almeida Penteado Simeão, Alberto De Vitta,
Abstract Introduction: Low back pain has varied etiology and complex discussed and can be triggered by various factors. Objective: Was to assess the prevalence of low back pain in individuals 60 years or more of the areas of the Family Health Strategy “Vila Sao Paulo” in the city of Bauru, São Paulo, and its association with demographic and socioeconomic variables, relating to work, lifestyle and morbidity. Methods: We conducted a cross-sectional study with 363 elderly sampled by the technique of ...
Tópico(s): Health, Nursing, Elderly Care
2017 - PONTIFÍCIA UNIVERSIDADE CATÓLICA DO PARANÁ | Fisioterapia em Movimento
Produção Nacional
Revisado por pares
Vanessa Mendonça, Carolina Madeira, Marta Dias, Fanny Vermandele, Philippe Archambault, Awantha Dissanayake, João Canning‐Clode, Augusto A. V. Flores, Ana Silva, Catarina Vinagre,
Understanding the fundamental laws that govern complex food web networks over large ecosystems presents high costs and oftentimes unsurmountable logistical challenges. This way, it is crucial to find smaller systems that can be used as proxy food webs. Intertidal rock pool environments harbour particularly high biodiversity over small areas. This study aimed to analyse their food web networks to investigate their potential as proxies of larger ecosystems for food web networks research. Highly resolved ...
Tópico(s): Evolutionary Game Theory and Cooperation
2018 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Riccardo Pofi, Alessandro Prete, Vivien Thornton-Jones, Jillian Bryce, Salma Ali, S. Faisal Ahmed, Antonio Balsamo, Federico Baronio, Amalia Cannuccia, Ayla Güven, Tülay Güran, Feyza Darendelıler, Claire Higham, Walter Bonfig, Liat de Vries, Tânia A.S.S. Bachega, Mirela Costa de Miranda, Berenice B. Mendonça, Violeta Iotova, Márta Korbonits, Nils Krone, Ruth Krone, Andrea Lenzi, Wiebke Arlt, Richard Ross, Andrea M. Isidori, Jeremy Tomlinson,
Abstract Context No consensus exists for optimization of mineralocorticoid therapy in patients with primary adrenal insufficiency. Objective To explore the relationship between mineralocorticoid (MC) replacement dose, plasma renin concentration (PRC), and clinically important variables to determine which are most helpful in guiding MC dose titration in primary adrenal insufficiency. Design Observational, retrospective, longitudinal analysis. Patients A total of 280 patients (with 984 clinical visits ...
Tópico(s): Hormonal Regulation and Hypertension
2019 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Produção Nacional
Revisado por pares
Vilma Bragas de Oliveira, Marta Simone Mendonça Freitas, Lêda Mathias, Raimundo Braz‐Filho, Ivo José Curcino Vieira,
Embora sejam conhecidas principalmente como fonte de madeira nobre para aplicação na construção de móveis, as espécies do gênero Aspidosperma apresentam muitos estudos na área da fitoquímica e poucos estudos na área da farmacologia. As espécies do gênero Aspidosperma são largamente aplicadas por populares como potenciais agentes antimaláricos, no tratamento da leishmaniose, de inflamações do útero e ovário, como anticonceptiva, em diabetes e em problemas estomacais, contra câncer, febre e reumatismo. ...
Tópico(s): Chemical synthesis and alkaloids
2009 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | Revista Brasileira de Plantas Medicinais
Produção Nacional
Revisado por pares
Marta Simone Mendonça Freitas, Pedro Henrique Monnerat, Ivo José Curcino Vieira,
ABSTRACT A greenhouse experiment was performed to evaluate macronutrients and boron deficiencies on vitexin bioproduction by sweet passion fruit leaves. Sand irrigated with nutrient solution was used as substrate in a complete randomized design, with eight treatments: 1) complete, 2) nitrogen-deficient(-N), 3) phosphorus-deficient(-P), 4) potassium-deficient(-K), 5) calcium-deficient(-Ca), 6) magnesium-deficient(-Mg), 7) sulfur-deficient(-S), and 8) boron-deficient(-B). After thirty days, the fourth ...
Tópico(s): Growth and nutrition in plants
2008 - Taylor & Francis | Journal of Plant Nutrition
Produção Nacional
Marta Simone Mendonça Freitas, Pedro Henrique Monnerat, Almy Júnior Cordeiro de Carvalho, Marco Antônio da Silva Vasconcellos,
Conduziu-se experimento em casa de vegetação com objetivo de caracterizar sintomas visuais de deficiências de macronutrientes e de B em folhas e frutos de maracujazeiro-doce cultivados em caixas com areia lavada e irrigados com solução nutritiva. Utilizou-se delineamento experimental em blocos casualizados, com oito tratamentos (solução completa, -N, -P, -K, -Ca, -Mg, -S e -B), com quatro repetições. Os sintomas de deficiência observados, entre 85 e 240 dias após a aplicação dos tratamentos, foram: -N: clorose ...
Tópico(s): Plant Physiology and Cultivation Studies
2011 - Sociedade Brasileira de Fruticultura | Revista Brasileira de Fruticultura
Produção Nacional
Marta Simone Mendonça Freitas, Pedro Henrique Monnerat, Leandro Glaydson da Rocha Pinho, Almy Júnior Cordeiro de Carvalho,
Conduziu-se um experimento em casa de vegetação com o objetivo de avaliar a qualidade dos frutos de maracujazeiro doce cultivado sob deficiência de macronutrientes e B. O delineamento experimental foi em blocos casualizados, com o oito tratamentos (solução completa, -N, -P, -K, -Ca, -Mg, -S e B), com quatro repetições. Utilizaram-se, como unidade experimental, caixas com 46 kg de areia lavada, contendo duas plantas/caixa, irrigadas com solução nutritiva. Todas as deficiências reduziram o número de frutos/ ...
Tópico(s): Soil Management and Crop Yield
2006 - Sociedade Brasileira de Fruticultura | Revista Brasileira de Fruticultura
Produção Nacional
Revisado por pares
Ana Cristina Fermino Soares, Marco Antônio Martins, Lêda Mathias, Marta Simone Mendonça Freitas,
Composition and the role of root flavonoids in the regulation of mycorrhizal symbiosis are still poorly understood. Several flavonoids stimulate spore germination, mycelia growth and root colonization by arbuscular mycorrhizal fungi (AMF), and both root colonization and flavonoid composition are affected by plant nutritional status. Effects of AMF on the occurrence and content of aromatic secondary metabolites in the roots of passion fruit seedlings grown under two levels of phosphorus (P) fertilization ( ...
Tópico(s): Fungal Biology and Applications
2005 - UNIVERSIDADE DE SÃO PAULO | Scientia Agricola
Produção Nacional
Revisado por pares
Marta Simone Mendonça Freitas, Marco Antônio Martins, Ivo José Curcino Vieira,
O objetivo deste trabalho foi avaliar os efeitos de diferentes espécies de fungos micorrízicos arbusculares (FMA) na produção e qualidade de óleos essenciais de Mentha arvensis L., cultivada com diferentes doses de fósforo. O trabalho foi realizado em casa de vegetação e o delineamento estatístico utilizado foi de blocos ao acaso com 20 tratamentos, constituídos pela combinação de cinco tratamentos microbiológicos (Glomus clarum Nicolson & Schenck, Glomus etunicatum Becker & Gerdemann, Gigaspora margarita ...
Tópico(s): Plant Diversity and Evolution
2004 - Embrapa Informação Tecnológica | Pesquisa Agropecuária Brasileira
Produção Nacional
Revisado por pares
Sérgio Mendonça, Christina Ecclissato, Marta Sartori, Anita Paula Ortiz de Godoy, Rosângela Aparecida Guerzoni, Maristela Degger, José Pedrazzoli,
Background. Helicobacter pylori infection is associated with a wide range of digestive diseases and is very prevalent in developing countries, although few data exist on the susceptibility of H. pylori to antimicrobials commonly used in eradication schedules in these countries. The aim of this study was to evaluate the resistance of H. pylori to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone in dyspeptic Brazilian patients. Material and Methods. Ninety consecutive H. ...
Tópico(s): Gastrointestinal disorders and treatments
2000 - Wiley | Helicobacter