Patricia LoRusso, Emiliano Calvo, Noboru Yamamoto, Chia-Chi Lin, Thaddeus Beck, David Sommerhalder, Do‐Youn Oh, John D. Powderly, Talia Golan, Linu Abraham, Joel S. Hayflick, Tamar Uziel, Priya Brunsdon, Wijith Munasinghe, Marcia N. Paddock, Cathleen Brdlik Hartman, Jonathan D. Powell, Bruno C. Medeiros, Martha R. Neagu, Benedito A. Carneiro,
... Marcia Paddock, Cathleen Brdlik Hartman, Jonathan Powell, Bruno Medeiros, Martha R. Neagu, Benedito A. Carneiro. First-in-human ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2023 - American Association for Cancer Research | Cancer Research
Guillermo Garcia‐Manero, Yasmin Abaza, Koichi Takahashi, Bruno C. Medeiros, Martha Arellano, Samer K. Khaled, Mrinal M. Patnaik, Olatoyosi Odenike, Hamid Sayar, Mohan K. Tummala, Prapti A. Patel, Lori Maness-Harris, Robert K. Stuart, Elie Traer, Kasra Karamlou, Abdulraheem Yacoub, Richard Ghalie, R. Giorgino, Ehab Atallah,
Abstract Pracinostat, a potent oral pan-histone deacetylase inhibitor with modest single-agent activity in acute myeloid leukemia (AML), has shown synergistic antitumor activity when combined with azacitidine. This single-group, multicenter phase 2 study assessed the safety and efficacy of pracinostat combined with azacitidine in patients who were at least 65 years old with newly diagnosed AML and who were ineligible for standard induction chemotherapy. Patients received pracinostat 60 mg/d, 3 d/ ...
Tópico(s): Multiple Myeloma Research and Treatments
2019 - Elsevier BV | Blood Advances
Clarissa De Antoni, Fernanda B. de Medeiros, Martha M. W Hoppe, Sílvia Helena Koller,
Tópico(s): Resilience and Mental Health
1999 - Institute for Operations Research and the Management Sciences | INFORMS Journal on Applied Analytics
Produção Nacional
Revisado por pares
Mariana Medeiros Assed, Martha Kortas Hajjar Veiga de Carvalho, Cristiana Castanho de Almeida Rocca, Antônio de Pádua Serafim,
Studies emphasize the training of cognitive functions to decrease losses in the population. Memory training associated with neurotracker was performed by an 80-year-old man with memory complaints. A battery for measuring memory, quality of life and stress was initially applied and showed low scores. The patient underwent a program for stimulating memory and attention comprising 32 sessions (2 weekly sessions of 90 minutes each). The post-test follow-up showed improvements in the process of storage ...
Tópico(s): Cognitive Functions and Memory
2016 - Associação Neurologia Cognitiva e do Comportamento | Dementia & Neuropsychologia
Produção Nacional
Revisado por pares
Márcia Melo Medeiros, Wesley Luzetti Fotoran, Rosimeire Cristina Dalla Martha, Tony Hiroshi Katsuragawa, Luiz Hildebrando Pereira da Silva, Gerhard Wunderlich,
Abstract Background Antibodies have an essential role in the acquired immune response against blood stage P. falciparum infection. Although several antigens have been identified as important antibody targets, it is still elusive which antigens have to be recognized for clinical protection. Herein, we analyzed antibodies from plasmas from symptomatic or asymptomatic individuals living in the same geographic area in the Western Amazon, measuring their recognition of multiple merozoite antigens. Methods ...
Tópico(s): Vector-borne infectious diseases
2013 - BioMed Central | BMC Infectious Diseases
Stéphanie Arrivault, Thiago Alexandre Moraes, Toshihiro Obata, David B. Medeiros, Alisdair R. Fernie, Alix Boulouis, Martha Ludwig, John E. Lunn, Gian Luca Borghi, Armin Schlereth, Manuela Guenther, Mark Stitt,
Low atmospheric CO2 in recent geological time led to the evolution of carbon-concentrating mechanisms (CCMs) such as C4 photosynthesis in >65 terrestrial plant lineages. We know little about the impact of low CO2 on the Calvin–Benson cycle (CBC) in C3 species that did not evolve CCMs, representing >90% of terrestrial plant species. Metabolite profiling provides a top-down strategy to investigate the operational balance in a pathway. We profiled CBC intermediates in a panel of C4 (Zea mays, Setaria viridis, ...
Tópico(s): Lipid metabolism and biosynthesis
2019 - Oxford University Press | Journal of Experimental Botany
Produção Nacional
Revisado por pares
Maria Cecília Mireski, Roberta Sales Guedes, Ivar Wendling, Antônio Carlos de Souza Medeiros, Martha Lucía Peña Peña,
A germinação de erva-mate tem sido apontada como baixa, irregular e lenta, com diferentes graus de dormência, tornando a produção de mudas um grande desafio. Estudos destinados a esclarecer os principais mecanismos de dormência presentes em sementes de erva-mate são de grande importância, porém, escassos. Diante disso, objetivou-se avaliar os efeitos da secagem na viabilidade e no desenvolvimento embrionário de sementes da espécie. A avaliação do efeito da secagem foi realizada mediante determinação ...
Tópico(s): Plant tissue culture and regeneration
2019 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Florestal
Produção Nacional
Revisado por pares
Martha Newson, Victor Kenji Medeiros Shiramizu, Michael D. Buhrmester, Wallisen Tadashi Hattori, Jonathan Jong, Emilia Yamamoto, Harvey Whitehouse,
Why do some sports fans experience intense emotions when watching live matches? Identity fusion is a strong form of group alignment in which personal and group identities are activated synergistically to produce a visceral sense of 'oneness' with one's team. Here we examine the role of fusion (using a three-item state measure with high internal validity) in elevating salivary cortisol levels while watching football (n = 41). Our evidence was gathered at field laboratories during the 2014 sFIFA World ...
Tópico(s): Behavioral Health and Interventions
2020 - Wiley | Stress and Health
... trabalho tem como objeto as escrituras da brasileira Martha Medeiros e da portuguesa Ines Lourenco, ambas autoras da ...
Tópico(s): Gender, Sexuality, and Education
2011 - UNIVERSIDADE ESTADUAL DE MARINGÁ | Revista Diálogos
Produção Nacional
Letícia Oliveira de Lima, Amanda Canterle Bochett, Angela Maria Rossi, Daniela Leite Rodrigues,
... na capa do livro “Doidas e santas”, de Martha Medeiros. O primeiro passo da análise consiste na identificação ...
Tópico(s): Linguistics and Discourse Analysis
2016 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Linguagens & Cidadania
Rosiane Moreira da Silva Swiderski,
... apresenta uma análise retórica da crônica "Ela", de Martha Medeiros, com o objetivo de explorar as estratégias argumentativas ...
Tópico(s): Linguistics and Education Research
2024 - | Temática
Produção Nacional
J. A. Pires, Fani Miranda Tabak,
... propôs-se a analisar a obra “Divã”, de Martha Medeiros, no que tange ao subgênero romance de formação/ ...
Tópico(s): Cultural, Media, and Literary Studies
2021 - | Revista Intertexto
Gian Luca Borghi, Stéphanie Arrivault, Manuela Günther, David B. Medeiros, Emilia Dell’Aversana, Giovanna Marta Fusco, Petronia Carillo, Martha Ludwig, Alisdair R. Fernie, John E. Lunn, Mark Stitt,
C4 photosynthesis concentrates CO2 around Rubisco in the bundle sheath, favouring carboxylation over oxygenation and decreasing photorespiration. This complex trait evolved independently in >60 angiosperm lineages. Its evolution can be investigated in genera such as Flaveria (Asteraceae) that contain species representing intermediate stages between C3 and C4 photosynthesis. Previous studies have indicated that the first major change in metabolism probably involved relocation of glycine decarboxylase ...
Tópico(s): Algal biology and biofuel production
2021 - Oxford University Press | Journal of Experimental Botany
Tópico(s): Literature, Culture, and Criticism
2013 - | Aleph UCLA Undergraduate Research Journal for the Humanities and Social Sciences
Produção Nacional
Revisado por pares
Fernanda Janku Cabral, Luciana G Vianna, Márcia Melo Medeiros, Bianca Cechetto Carlos, Rosimeire D Martha, Nadia Maria Silva, Luiz Hildebrando P da Silva, Rodrigo G. Stábeli, Gerhard Wunderlich,
The surface of infected red blood cells (iRBCs) has been widely investigated because of the molecular complexity and pathogenesis mechanisms involved. Asymptomatic individuals are important in the field because they can perpetuate transmission as natural reservoirs and present a challenge for diagnosing malaria because of their low levels of circulating parasites. Recent studies of iRBC antibody recognition have shown that responses are quantitatively similar in symptomatic and asymptomatic infections, ...
Tópico(s): Vector-borne infectious diseases
2017 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
... da cronica Os Ricos e Pobres, escrita por Martha Medeiros e publicada no caderno Donna, do jornal Zero ... apresentadas por quem realiza a producao, neste caso, Martha Medeiros, e que se tornam elementos linguisticos importantes para quem consome, ou seja, os leitores do caderno Donna, especificamente da coluna produzida por Martha. Assim, acredita-se que tal analise seja de ...
Tópico(s): Discourse Analysis in Language Studies
2007 - | Línguas & letras
Produção Nacional
Revisado por pares
Pedro Augusto Medeiros Barbosa, Roberto Fritsche‐Neto, Marcela Carvalho Andrade, César Daniel Petroli, Juan Burgueño, Giovanni Galli, Martha C. Willcox, Kai Sonder, Víctor A. Vidal-Martínez, Ernesto Sifuentes‐Ibarra, Terence Molnar,
Current climate change models predict an increased frequency and intensity of drought for much of the developing world within the next 30 years. These events will negatively affect maize yields, potentially leading to economic and social instability in many smallholder farming communities. Knowledge about the genetic resources available for traits related to drought tolerance has great importance in developing breeding program strategies. The aim of this research was to study a maize landrace introgression ...
Tópico(s): Genetic and phenotypic traits in livestock
2021 - Frontiers Media | Frontiers in Plant Science
Produção Nacional
Revisado por pares
Martha Schaer-Barbosa, Elisabete Santos, Yvonilde Dantas Pinto Medeiros,
Este artigo tem o objetivo de avaliar a viabilidade de implantação do reúso agrícola de água como elemento mitigador dos efeitos da seca no semiárido baiano, analisando as razões para a implementação de políticas de reúso de água sob o ponto de vista de agricultores e de formuladores de política de recursos hídricos. A pesquisa foi localizada em São Domingos, município da região semiárida da Bahia e a metodologia consistiu na realização de entrevistas semiestruturadas e aplicação de questionários ...
Tópico(s): Environmental Sustainability and Education
2014 - Associação Nacional de Pós-Graduação e Pesquisa em Ambiente e Sociedade (ANPPAS) | Ambiente & sociedade
Gina Casagrande, Jeffery LeJeune, Martha A. Belury, Lydia C. Medeiros,
The Theory of Planned Behavior was used to determine if dietitians personal characteristics and beliefs about fresh vegetable food safety predict whether they currently teach, intend to teach, or neither currently teach nor intend to teach food safety information to their clients. Dietitians who participated in direct client education responded to this web-based survey (n = 327). The survey evaluated three independent belief variables: Subjective Norm, Attitudes, and Perceived Behavioral Control. Spearman ...
Tópico(s): Environmental Education and Sustainability
2011 - Elsevier BV | Appetite
Produção Nacional
Revisado por pares
Martha Traverso-Yépez, Luciana Fernandez de Medeiros,
The expression “suffering from nerves” is a common complaint among lower income women in Brazil. It is used to express a generalized and usually chronic suffering with a variety of physiological, physical, and psychological symptoms. Public health professionals have trouble with this condition, in which mental and physical factors seem to interact in a complex manner. Empirical evidence comes from broader research developed at a public health unit in a lower income district in the city of Natal in ...
Tópico(s): Youth, Drugs, and Violence
2005 - SAGE Publishing | Qualitative Health Research
Koichi Takahashi, Yasmin Abaza, Ehab Atallah, Bruno C. Medeiros, Sam Khal, Martha Arellano, Mrinal M. Patnaik, Richard Ghalie, Guillermo Garcia‐Manero,
7034 Background: In a phase II study in 50 elderly patients (pts) with AML who were not eligible for intensive chemotherapy, treatment with pracinostat + azacitidine (AZA) was well tolerated, led to 42% complete remission (CR) rate and a median overall survival (OS) of 19.1 months (Blood 2016: 128;100). Here we investigate the impact of somatic mutations and their clearance on disease response and patient outcomes. Methods: 88 samples from 41 study pts were sequenced. All 41 pts were analyzed pre-treatment, ...
Tópico(s): Cancer Genomics and Diagnostics
2017 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Produção Nacional
Revisado por pares
Víctor Rosenthal, Dennis G. Maki, Camila Eleutério Rodrigues, Carlos Álvarez, Hakan Leblebicioğlu, Martha Sobreyra-Oropeza, Regina Berba, Naoufel Madani, Eduardo Alexandrino Medeiros, Luis E. Cuéllar, Zan Mitrev, Lourdes Dueñas, Humberto Guanche Garcell, Trudell Mapp, Souha S. Kanj, Rosalía Fernández-Hidalgo,
The International Nosocomial Infection Control Consortium (INICC) was established in 15 developing countries to reduce infection rates in resource-limited hospitals by focusing on education and feedback of outcome surveillance (infection rates) and process surveillance (adherence to infection control measures). We report a time-sequence analysis of the effectiveness of this approach in reducing rates of central line-associated bloodstream infection (CLABSI) and associated deaths in 86 intensive care ...
Tópico(s): Nosocomial Infections in ICU
2010 - Cambridge University Press | Infection Control and Hospital Epidemiology
William D. Hinsberg, Gregory M. Wallraff, Carl E. Larson, Blake Davis, V. R. Deline, Simone Raoux, Dolores C. Miller, Frances A. Houle, John A. Hoffnagle, Martha I. Sanchez, Charles Rettner, Linda K. Sundberg, David R. Medeiros, Ralph R. Dammel, Willard E. Conley,
We address in this report a set of key questions tied to the implementation of liquid immersion lithography, from the perspective of the resist materials. We discuss the broad question of whether chemically amplified resists are capable of achieving the spatial resolution that ultimately will be required for the most advanced immersion scenario. Initial studies undertaken using model 193 nm resist materials provide some insight into how an aqueous liquid immersion process can affect the resist material.
Tópico(s): Advanced Surface Polishing Techniques
2004 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Produção Nacional
Revisado por pares
Isabella Patrícia Lima Silva, Andréa Dória Batista, Edmundo Pessoa Lopes, Norma Arteiro Filgueira, Bernardo Times de Carvalho, Joelma Carvalho Santos, Tibério Batista de Medeiros, Clarissa Ramos Lacerda de Melo, Martha Sá de Lima, Kledoaldo Lima, Cláudio Moura Lacerda, Heloísa Ramos Lacerda,
The efficacy of direct-acting antivirals (DAAs) in the treatment of chronic hepatitis C (CHC) in liver transplant recipients is poorly understood, and several factors, including immunosuppression, drug interactions, elevated viraemia, and intolerance to ribavirin (RBV), can reduce cure rates. We conducted a real-life study on liver transplant recipients with CHC treated with a combination of sofosbuvir (SOF) and daclatasvir (DCV) or simeprevir (SIM), with or without RBV, followed-up for 12 to 24 weeks. ...
Tópico(s): Hepatitis B Virus Studies
2021 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo
James W. Thackeray, Diane L. Canistro, Mark Denison, Joseph J. Ferrari, Richard C. Hemond, David R. Medeiros, George W. Orsula, Edward K. Pavelchek, Martha M. Rajaratnam, Roger F. Sinta,
This paper reports the initial results of an improved chemically amplified, positive-tone photoresist for use in DUV applications. This photoresist is shown to have the following properties: low absorbance at 248 nm (0.22/micrometers ), high resolution (0.35 micrometers lines and spaces in 1.0 micrometers thick resist), and good environmental stability. The resist did not show evidence of `T-tops' nor did any linewidth change occur over a five hour period.
Tópico(s): Advanced Memory and Neural Computing
1992 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
William D. Hinsberg, Frances A. Houle, Martha I. Sanchez, John A. Hoffnagle, Gregory M. Wallraff, David R. Medeiros, Gregg M. Gallatin, Jonathan Cobb,
The chemically amplified resist concept, first described two decades past and originally targeted for the 1000 nm device generation, has proved to have remarkable versatility. The semiconductor industry has come to rely on the properties of CA resists to achieve high resolution, high aspect ratio imaging accompanied by the high throughput that stems from their catalytic imaging mechanism. As the industry maps the evolution of lithographic technology to the 20 nm regime, it is appropriate to review ...
Tópico(s): Integrated Circuits and Semiconductor Failure Analysis
2003 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
... rendeiras salomeenses com sua principal compradora, a empresária Martha Medeiros. Dessa forma, o trabalho traz um panorama da ...
Tópico(s): Social and Economic Solidarity
2023 - UNIVERSIDADE FEDERAL DO CEARÁ | Geosaberes
Guillermo Garcia‐Manero, Ehab Atallah, Samer K. Khaled, Martha Arellano, Mrinal M. Patnaik, Todd Butler, Carla Ashby, Bruno C. Medeiros,
Tópico(s): Protein Degradation and Inhibitors
2015 - Elsevier BV | Blood
Produção Nacional
Revisado por pares
Carlos Alexandre Rodrigues Pereira, Martha Macêdo de Lima Barata, Melania de Paulo Cariello Hoelz, Viviane Nunes Lopes Oliveira Medeiros, Felipe de Carvalho Vommaro Marincola, Cristina Costa Neto, Diana Pinheiro Marinho, Teresa Vieira dos Santos de Oliveira, Aline Guimarães Monteiro Trigo, Thiago Klein de Medeiros,
The prospects outlined in climate scenarios produced for Brazil indicate a probable increase in the number of extreme hydrometeorological events in the coming years. Therefore, a study of the health scourges that may intensify due to these events is important. The scope of this article is to estimate the cost represented by the cases of dengue fever attributed to the 2011 disaster in Nova Friburgo (RJ). There were 1,356 suspected cases of dengue fever, 937 of which were confirmed. The total cost ...
Tópico(s): Vibrio bacteria research studies
2014 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Martha Luísa Machado, Vanessa Rodrigues, Amanda Bagolin do Nascimento, Moira Dean, Giovanna Medeiros Rataichesck Fiates,
Most food industry marketing in products targeted at children is found in packages of foods containing either excessive fat, sugar, or salt. This study audited all 5620 packaged foods available in a store of a large Brazilian supermarket chain and retrieved information from the nutrition facts tables on package labels. Products were photographed for further visual analysis to determine the presence of marketing strategies directed at children. Comparison of nutrient content per 100 g between children' ...
Tópico(s): Nutritional Studies and Diet
2019 - Multidisciplinary Digital Publishing Institute | Nutrients