Tópico(s): Collaborative Teaching and Inclusion
1998 - | Teacher education quarterly (Claremont, Calif.)
Michaela Scherr, Karin Battmer, Iris Dallmann, Arnold Ganser, Matthias Eder,
RNA interference (RNAi) describes a highly conserved mechanism of sequence-specific posttranscriptional gene silencing triggered by double-stranded RNA (dsRNA). Whereas RNAi is applied to study gene function in different organisms and in variant cell types, little is known about RNAi in human hematopoietic stem and progenitor cells and their myeloid progeny. To address this issue, short hairpin RNAs (shRNA) were designed to target the common β-chain of the human receptors for granulocyte-macrophage ...
Tópico(s): Virus-based gene therapy research
2003 - Mary Ann Liebert, Inc. | Oligonucleotides
Gerasimos Anastassiou, Stefan Duensing, Gustav Steinhoff, Hartmut Kirchner, Arnold Ganser, Jens Atzpodien,
We studied 23 renal cell carcinomas and two normal kidney tissues by immunohistochemistry using monoclonal antibodies against subunits of the VLA integrins (VLA-1 to VLA-6) and CD51. All integrins investigated in our study, except VLA-4 (ubiquitous negative), were distributed in different patterns in tumors assayed. We found a correlation between VLA-2 expression and site of tissue; primary tumor cells expressed no VLA-2 integrin, whereas tumor cells from metastatic tissues exhibited VLA-2 positivity ( ...
Tópico(s): Protease and Inhibitor Mechanisms
1995 - Mary Ann Liebert, Inc. | Cancer Biotherapy
Arne Trummer, János Kádár, Lubomir Arseniev, Detlev Petersen, Arnold Ganser, Ralf Lichtinghagen,
Detection of residual tumor cells in BM and PBPC products has been correlated with worse outcome of breast cancer patients. Still, there is a considerable demand for studies investigating the influence of the actual tumor cell number on prognosis, as quantification routinely has been cumbersome and time consuming and, thus, was evaded. We developed and evaluated a competitive RT-PCR-ELISA assay for cytokeratin 19 (CK19) with standard curve quantification that allows quantification of multiple samples ...
Tópico(s): Cancer Cells and Metastasis
2000 - Mary Ann Liebert, Inc. | Journal of Hematotherapy & Stem Cell Research
R. G. Geißler, Oliver G. Ottmann, G. Kojouharoff, P. Reutzel, M Eder, D. Hoelzer, Arnold Ganser,
As a result of a pathophysiologically unexplainable bone marrow failure, most patients with progressive stages of human immunodeficiency virus (HIV) infection develop anemia, leukopenia, and thrombocytopenia. Besides the possibility of immune-mediated cytolysis or of direct viral infection of hemopoietic progenitor cells, the inhibitory influence of cytokines, for example interferon-α (IFN-α) and IFN-γ, on hemopoiesis of HIV-infected patients might be considered as one parameter that contributes to ...
Tópico(s): Hepatitis B Virus Studies
1992 - Mary Ann Liebert, Inc. | AIDS Research and Human Retroviruses
Sven Becker, Sandra Wasser, Martin Hauses, Johann Peter Hossle, Marion Ott, Mary C. Dinauer, Arnold Ganser, Dieter Hoelzer, Reinhard Seger, Manuel Grez,
Chronic granulomatous disease (CGD) is a disorder of the lymphohematopoietic system, whereby phagocytes of affected patients are unable to kill microorganisms. CGD is caused by a functional defect in the phagocytic nicotinamide adenine dinucleotide phosphatase (NADPH) oxidase (phox) enzyme complex, leading to a lack of microbicidal metabolites. As a therapeutic approach toward the predominant X-linked form of CGD, we have developed a bicistronic retroviral vector containing the coding sequences of ...
Tópico(s): Calcium signaling and nucleotide metabolism
1998 - Mary Ann Liebert, Inc. | Human Gene Therapy
R. G. Geißler, Rita Rossol, Ulrich Mentzel, Oliver G. Ottmann, Andreas Klein, Peter Gute, E. B. Helm, D. Hoelzer, Arnold Ganser,
In severe HIV infection, the majority of patients exhibit signs of hematopoietic deficiency including anemia, leukopenia, and thrombocytopenia. Besides other pathophysiological mechanisms, the disturbed helper/suppressor ratio of T-lymphocytes suggests that alterations within T cell subpopulations may have a suppressive effect on HIV-associated hematopoiesis. Since a δTCS-1- and mostly CD-8-positive subpopulation of cytotoxic T-lymphocytes expressing the γδ-receptor is increased in peripheral blood ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
1996 - Mary Ann Liebert, Inc. | AIDS Research and Human Retroviruses
Anke Franzke, Jan Buer, Michaël Probst-Kepper, Christian Lindig, Marcus Framzle, Andres J. Schrader, Arnold Ganser, Jens Atzpodien,
Background: The natural history of malignancies, the response to cytokine-based therapy and survival of patients may be partly determined by the human leukocyte antigen (HLA) phenotype. Here, we investigated in a retrospective analysis the correlation of the HLA phenotype of 73 prognostic favored patients with advanced renal cell carcinoma to (a) the expected HLA distribution in Caucasians, (b) the susceptibility or resistance to metastatic sites, (c) response to cytokine-based therapy and (d) sustained ...
Tópico(s): Bladder and Urothelial Cancer Treatments
2001 - Mary Ann Liebert, Inc. | Cancer Biotherapy and Radiopharmaceuticals
Jan Buer, Michael Probst, Stefan Duensing, H Köditz, Anke Franzke, Iris Dallmann, Arnold Ganser, Jens Atzpodien,
Retinoids are known to control many important biological processes, including differentiation, morphogenesis, growth and tissue homeostasis. More recently, clinical and pre-clinical results provide evidence for an antiproliferative effect of 13-cis-retinoic acid (13cRA) in interferon-alpha (IFN-alpha) treated renal cell carcinoma patients. The manner in which 13cRA augments antitumor effects and modulates biologic and clinical responses of renal cell carcinoma to IFN-alpha remains elusive. In the ...
Tópico(s): Lymphoma Diagnosis and Treatment
1997 - Mary Ann Liebert, Inc. | Cancer Biotherapy and Radiopharmaceuticals
Bala Sai Sundarasetty, Vijay Kumar Singh, Gustavo Salguero, Robert Geffers, Mareike Rickmann, Laura Macke, Sylvia Borchers, Constança Figueiredo, Axel Schambach, Urban Gullberg, Elena Provasi, Chiara Bonini, Arnold Ganser, Thomas Woelfel, Renata Stripecke,
Wilms' tumor 1 antigen (WT1) is overexpressed in acute myeloid leukemia (AML), a high-risk neoplasm warranting development of novel immunotherapeutic approaches. Unfortunately, clinical immunotherapeutic use of WT1 peptides against AML has been inconclusive. With the rationale of stimulating multiantigenic responses against WT1, we genetically programmed long-lasting dendritic cells capable of producing and processing endogenous WT1 epitopes. A tricistronic lentiviral vector co-expressing a truncated ...
Tópico(s): Immunotherapy and Immune Responses
2013 - Mary Ann Liebert, Inc. | Human Gene Therapy
Sylvia Borchers, Elena Provasi, Anna Silvani, Marina Radrizzani, Claudia Benati, Elke Dammann, Annika Krons, Julia Kontsendorn, Joerg Schmidtke, Wolfgang Kuehnau, Nils von Neuhoff, Michael Stadler, Fabio Ciceri, Chiara Bonini, Arnold Ganser, Bernd Hertenstein, Eva M. Weissinger,
Seven patients with acute myeloid leukemia (AML) and two patients with chronic myelogenous leukemia (CML) were transplanted from HLA-identical sibling donors with CD34(+) cell-enriched stem cells (HSCTs) without further immunosuppression. The myeloablative standard transplantation protocol was adapted to include transfusion of gene-modified donor T cells after HSCT. Donor T cells were transduced with the replication-deficient retrovirus SFCMM-3, which expresses herpes simplex thymidine kinase (HSV-Tk) ...
Tópico(s): CAR-T cell therapy research
2010 - Mary Ann Liebert, Inc. | Human Gene Therapy
Gustavo Salguero, Bala Sai Sundarasetty, Sylvia Borchers, Dirk Wedekind, Britta Eiz‐Vesper, Sarvari Velaga, Adan Chari Jirmo, Georg M. N. Behrens, G. Warnecke, Ann-Kathrin Knöfel, Rainer Blasczyk, Eva M. Weissinger, Arnold Ganser, Renata Stripecke,
Dendritic cell (DC)-based immunization is a potent strategy to direct prompt and durable immune responses against viral reactivations after transplantations. Here, we show that overnight lentiviral vector (LV) gene transfer into human monocytes co-expressing granulocyte-macrophage colony stimulating factor and interleukin (IL)-4 induced self-differentiated DCs (SMART-DCs) with stable DC immunophenotype over weeks in culture and secreted several inflammatory cytokines. SMART-DCs injected subcutaneously ...
Tópico(s): Immune Cell Function and Interaction
2011 - Mary Ann Liebert, Inc. | Human Gene Therapy
Lubomir Arseniev, N. Pickerd, Lilia Goudeva, Bernd Hertenstein, Arnold Ganser,
CD34+ cell enumeration is currently the most appropriate technique for hematopoietic graft quality control. At the same time, numerous CD34 mAb have become commercially available. This study was designed to compare the commonly used clones 8G12 and QBEND-10 with the new clones 581 and BIRMA-K3. All available fluorochrome conjugates were tested: FITC, PE, and PE-Cy5 or PerCP for QBEND, BIRMA, 581, and 8G12 and FITC and PE for 581. Bone marrow from healthy donors (n = 5) and leukapheresis samples (n = 16) ...
Tópico(s): Acute Myeloid Leukemia Research
1999 - Mary Ann Liebert, Inc. | Journal of Hematotherapy & Stem Cell Research
Jürgen Krauter, Michael W Hartl, Lothar Hambach, Anke Kohlenberg, Eberhard Gunsilius, Arnold Ganser, Gerhard Heil,
CD34 most probably acts as a receptor molecule on hematopoietic progenitor cells; however, its precise function remains to be elucidated. To track the intracellular pathway of CD34 after binding of a stimulatory antibody (anti-HPCA-1), immuno-electron microscopical analysis was performed on cells of normal bone marrow (NBMPC), acute leukemias, and the KG1a cell line. Before stimulation, CD34 was evenly distributed over the cell surface. After binding of the anti-HPCA-1, but not the anti-HPCA-2 antibody ...
Tópico(s): Immunotherapy and Immune Responses
2001 - Mary Ann Liebert, Inc. | Journal of Hematotherapy & Stem Cell Research
Stefan Nagel, Lothar Hambach, Jürgen Krauter, Letitia Venturini, Olaf Heidenreich, Arnold Ganser, Gerhard Heil,
The AML1/ETO protein derived from the t(8;21) translocation retains the DNA binding domain of AML1, the runt homology domain (RHD), and nearly the complete ETO protein with its four nervy homology regions (NHR1-4). To analyze which domains of AML1/ETO are responsible for its intranuclear transport and its subnuclear distribution, AML1/ETO deletion constructs tagged with green fluorescence protein were expressed transiently in 293 cells. The subcellular distribution was analyzed by confocal laser scanning ...
Tópico(s): Retinoids in leukemia and cellular processes
2002 - Mary Ann Liebert, Inc. | Journal of Hematotherapy & Stem Cell Research
Anuhar Chaturvedi, Karin Battmer, Daniel Schaefer, Arnold Ganser, Matthias Eder, Michaela Scherr,
Accumulating knowledge about the molecular mechanisms causing human diseases can support the development of targeted therapies such as imatinib, a BCR-ABL-specific tyrosine kinase inhibitor to treat chronic myeloid leukemia (CML). Here, we use lentivirus-mediated RNA interference (RNAi) targeting BCR-ABL and the downstream signaling molecules SHP2, STAT5, and Gab2 to compare the efficacy and specificity of molecularly defined therapeutics with that of conventional cytotoxic drugs (cytarabine, doxorubicin, ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2007 - Mary Ann Liebert, Inc. | Oligonucleotides
Anette Duensing, A. Nasarek, Jens Grosse, Arnold Ganser, Jens Atzpodien,
Plasma IL-1Ra levels and cellular BCL-2 oncoprotein expression were measured in a total of forty blood samples obtained from twenty-eight B-CLL patients and four healthy subjects. High IL-1Ra plasma levels (as defined by mean + three times standard deviation of normal controls) were observed in eleven samples (ten patients) which showed a significantly decreased cellular expression of BCL-2 protein (14.7±16.3%) of cells as determined by immunofluorescence) when compared to B-CLL samples with no elevated ...
Tópico(s): Lymphoma Diagnosis and Treatment
1998 - Mary Ann Liebert, Inc. | Cancer Biotherapy and Radiopharmaceuticals
Ethan Fechter-Leggett, Kathleen B. Fedan, Jean M. Cox‐Ganser, Martin I. Meltzer, Bishwa B. Adhikari, Chad Dowell,
Early in the COVID-19 pandemic, demand for N95 respirators far exceeded the supply, leading to widespread shortages. Initially, the US Centers for Disease Control and Prevention did not recommend N95 respirators in nonhealthcare settings, in order to reserve them for healthcare workers. As N95s became more available, the recommendations were updated in May 2021 to include N95 respirators for nonhealthcare settings. In this study, we estimated the numbers of N95s needed for nonhealthcare essential ...
Tópico(s): COVID-19 epidemiological studies
2022 - Mary Ann Liebert, Inc. | Health Security
R. G. Geißler, Arnold Ganser, Oliver G. Ottmann, G. Kojouharoff, P. Reutzel, Koen Andries, K H Schellekens, D. Hoelzer,
In progressive stages of infection with human immunodeficiency virus type 1 (HIV-1), the majority of patients develop a pathophysiologically not yet completely explainable bone marrow failure with anemia, leukopenia, and thrombocytopenia. The clinically most widely used HIV-inhibiting antiviral drugs azidothymidine (AZT) and dideoxyinosine (ddI) frequently are hematotoxic to the host, resulting in dose reduction or discontinuation of antiviral therapy. In recent studies, a novel series of benzodiazepine ...
Tópico(s): Biochemical and Molecular Research
1991 - Mary Ann Liebert, Inc. | AIDS Research and Human Retroviruses
Stefan Duensing, H Hamm, Arnold Ganser, Jens Atzpodien,
Cancer Biotherapy & RadiopharmaceuticalsVol. 12, No. 3 Safety, Feasibility and Therapeutic Activity of Intrapleural Autologous Lymphocyte Conditioned Medium Followed by Systemic Recombinant Interleukin-2 and Interferon-α in a Patient with Malignant Pleural MesotheliomaStefan Duensing, Hinrich Hamm, Arnold Ganser, and Jens AtzpodienStefan DuensingSearch for more papers by this author, Hinrich HammSearch for more papers by this author, Arnold GanserSearch for more papers by this author, and Jens AtzpodienSearch ...
Tópico(s): Cancer Research and Treatments
1997 - Mary Ann Liebert, Inc. | Cancer Biotherapy and Radiopharmaceuticals
Mudita Pincha, Bala Sai Sundarasetty, Gustavo Salguero, Ralf Gutzmer, Henk Garritsen, Laura Macke, Andreas Schneider, Daniela Lenz, Constança Figueiredo, Rainer Blasczyk, Eliana Ruggiero, Manfred Schmidt, Christof von Kalle, Christina Puff, Ute Modlich, Heiko von der Leyen, Daniel C. Wicke, Arnold Ganser, Renata Stripecke,
SmartDCs (Self-differentiated Myeloid-derived Antigen-presenting-cells Reactive against Tumors) consist of highly viable dendritic cells (DCs) induced to differentiate with lentiviral vectors (LVs) after an overnight ex vivo transduction. Tricistronic vectors co-expressing cytokines (granulocyte-macrophage-colony stimulating factor [GM-CSF], interleukin [IL]-4) and a melanoma antigen (tyrosine related protein 2 [TRP2]) were used to transduce mouse bone marrow cells or human monocytes. Sixteen hours after ...
Tópico(s): Virus-based gene therapy research
2012 - Mary Ann Liebert, Inc. | Human Gene Therapy Methods
Lubomir Arseniev, Bernd Hertenstein, Hartmut Link, Arnold Ganser, Stefan Serke,
Journal of HematotherapyVol. 7, No. 1 Stem Cell Mobilization in Normal DonorsLubomir Arseniev, Bernd Hertenstein, Hartmut Link, Arnold Ganser, and Stefan SerkeLubomir ArsenievSearch for more papers by this author, Bernd HertensteinSearch for more papers by this author, Hartmut LinkSearch for more papers by this author, Arnold GanserSearch for more papers by this author, and Stefan SerkeSearch for more papers by this authorPublished Online:27 Mar 2009https://doi.org/10.1089/scd.1.1998.7.5AboutSectionsPDF/ ...
Tópico(s): Ethics and Legal Issues in Pediatric Healthcare
1998 - Mary Ann Liebert, Inc. | Journal of Hematotherapy
Bradley J. Serpa, Jennifer D. Bullard, Victoria C. Mendiola, Crystal J. Smith, Brandon Stewart, Lisa R. Ganser,
Background: Prescriptive and illicit amphetamine (AMPH) use continues to increase along with the likelihood that during an individual's lifetime, the drug deleteriously influences the growth and connectivity of behavior circuits necessary for survival. Throughout ontogeny, neural circuits underlying these behaviors grow in complexity, gradually integrating many sensory inputs that trigger higher order coordinated motor responses. In the present study, we examine how AMPH disrupts the establishment ...
Tópico(s): Neuroendocrine regulation and behavior
2019 - Mary Ann Liebert, Inc. | Bioelectricity
D. Schmähl, M.v. Bülow, W Bätz, K.H. Pflüger, E. Lötzke, V. Cour, H. Langenbahn, E. Busse, B. Kornhuber, P. Unterburger, A. Sinop, W. Noder, M.R. Berger, M. Fink, L. Edler, H. Ehrhart, B. Mentges, Carsten N. Gutt, K. Pollow, H.‐J. Grill, E. Heidemann, B. Steinke, J. Hartlapp, K. Schumacher, K. Possinger, Sebastian Kunz, E. Neeser, G.v. Ingersleben, D. K. Hossfeld, Robert Waldmann, H. Köppler, I. Eschenbach, Rudolf Pfab, U. Bruntsch, W. Zeller, E.U. Steinhauer, C. Gropp, S. Oehl, H. Kuhn, P. Drings, H. H. Goßmann, K. Lennert, H. Stein, Rolf Holle, K. Havemann, K. Höffken, F. Overkamp, J. Stirbu, A. Grothey, D. Peest, H. Deicher, R. Coldewey, I.-M. von Broen, Ursula Cammerer, R. Hein, Lone Hoffmann, H. Konyar, E.D. Kreuser, J. Selbach, H.J. Weh, M. Flaßhove, D. Hoelzer, A. Ganser, Georg Maschmeyer, Hartmut Link, W. Hiddemann, Peter Meyer, M. Helmerking, D. Adam, H. Ludwig, Emanuel Fritz, H. Kotzmann, H. Gisslinger, S. Verhees, H. Flechtner, W. Queißer, M.E. Heim, Mary Ann Fritz, F.A. Trux, L. Edler, W. Queißer, H. O. Klein, M.E. Heim, R. Herrmann, D.K. Hossfeld, J.P. Obrecht, P. Preusser, Hans‐Joachim Schmoll, B. Steinke, H. Weh, H. Wilke, L. Edler,
Anläßlich der Erstzulassung vonNavclbine®-Ampullen in Frankreich veranstalteten die Laboratories Pierre Fabre Oncologie, Paris, ein Symposium, auf dem vorwiegend Kollegen aus Frankreich über den gegenwärtigen Stand der Phase-Iund -Il-Studien mit Navelbine® berichteten.Navelbine (NVB.Vinorelbine) ist ein semi-synthetisch herge stelltes Vinca-Alkaloid-Zytostatikum mit der chemischen Kurzbezeichnung Nor-5'anhydrovinblastin. Ähnlich wie die bisher bekannten Zytostatika Vincristin, Vindesin und Vinblastin ...
1990 - Karger Publishers | Oncology Research and Treatment
... Henis, MD; Susan Edwards, MS; Steven Zelenkofske, DO; Mary Ann Sellers, MSN; Robert M. Califf, MD; for the ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2003 - Lippincott Williams & Wilkins | Circulation
Eric E. Smith, Ashkan Shoamanesh, Lizhen Xu, Laura Heenan, Feryal Saad, Pablo Colorado, Chih‐Hao Chen, Robin Lemmens, Gian Marco De Marchis, Valeria Caso, Jaime Masjuán, Teruyuki Hirano, Ivan Milanov, Bruce Campbell, Jean‐Louis Mas, Stuart J. Connolly, Hardi Mundl, Robert G. Hart, Peter Bailey, Bruce Campbell, Timothy Kleinig, Dennis Cordato, Philip Choi, Carlos García-Esperón, Andrew Chew, Geoffrey Cloud, Vimal Stanislaus, Maurício Krause, Miriam Priglinger, Rohan Grimley, Darshan Ghia, Ramesh Sahathevan, Henry G. Brown, Chiu‐Yin Kwan, Michael J. Devlin, Stefan Greisenegger, S. Bonelli-Nauer, Jakob Rath, A. Langer, Martha Marko, Jéssica Tonin Ferrari, Alexandra Bernegger, M. Baumgartinger, Matthias Vigl, Stefan Krebs, W. Lang, M. Knoflach, Benjamin Dejakum, Sophia J. Kiechl, Thomas Töll, Lena Domig, Johannes Sebastian Mutzenbach, Bernhard Ganser, Constantin Hecker, Cornelia Rösler, Nele Bubel, Slaven Pikija, Tobias Zellner, Ursula Leitner, Otto Berger, B. Surböck, Sebastian Beirer, Dimitre Staykov, Daniel Schrammel, Altuna Halilović, Michael Frattner, D. Barmherzigen, Christian Lampl, Christopher Hofer, S. Nagl, Christoph Bocksrucker, Robin Lemmens, Jelle Demeestere, P. Desfontaines, C Ciobanu, Adinda De Pauw, Annelies Terwecoren, M.C. Hasenbroekx, Fiona Clement, Nina De Klippel, Peter Soors, Sabine Hermans, Sylvie De Raedt, Fenne Vandervorst, Laura Seynaeve, Niels Fockaert, Sofie de Smet, Matthieu Pierre Rutgers, Nicole Del Gaudio, Perrine Paindeville, Ivan Staikov, A. Simeonova, Irina I. Stoyanova, Maria Cholakova, N. Mihnev, T. Petrova, A. Koralova, D. Dimov, Y. Kuzev, Maya Danovska, Diana L. Marinova, D. Marinova-Trifonova, Emilia Ovcharova, Igor Mladenovski, Magdalina Yanakieva, Павел Стоев, Mariya Dimitrova, S. Todorova-Georgieva, L. Haralanov, B. Milkov, D. Solakov, Neli Petkova, V. Ignatova-Valkova, Vesselin Karabinov, Veselina Goranova‐Marinova, Y. Miteva, V. Andonova, D. Kasabova, E. Kostadinova, Y. Shopova-Vrabcheva, D. Gatev, Dimitrina Jivkova Semova, Eray Halil, Ara Kaprelyan, Borko Ivanov, G. Panov, Маргарита Грудкова, N. Syuleyman, R. Kalpachki, Filip Alexiev, I. Ivanova, K. Kancheva, Teodora Sakelarova, Dimitar Maslarov, Desislava Drenska, Vasil Georgiev, Е. Б. Петрова, N. V. Petrova, I. Ivanova, Ivan Milanov, N. Semerdjieva, P. Zhelyazkov, S. Spasova-Markova, Xiaofeng Dong, Defeng Wang, S. Wang, W. Huang, Hui Zhao, C. Wang, Jie Lu, Y. Xinyang, Ping Zhang, Qiang Dong, Yan‐Jiang Wang, Yan Fu-ling, W. Yue, Rui Liu, Y Yang, Ivana Štětkářová, Petr Mikulenka, Peter Vaško, Tomáš Peisker, Michal Bar, Martin Roubec, Robert Mikulík, M. Cabukova, Jan Vinklárek, Marek Kovář, M. Pansky, Pavel Mencl, Ondřej Škoda, M. Carek, Marek Pernicka, M Skodová, Petr Geier, Jitka Čepková, Jakub Drlík, Tomáš Prax, R H Herzig, Dagmar Krajíčková, Eva Vítková, Simona Halúsková, Daniel Václavík, J Martínková, K. Blejcharova, M. Tkacova, O. Pavlik, Miroslava Nevšímalová, J. Rosol, Miroslava Nevšímalová, Radovan Hrubý, Helle K. Iversen, A.V. Andersen, D. Rahimi, Hanne Christensen, Josefine Grundtvig, Niels Hjort, Gary L. Andersen, Birgitte Forsom Sandal, Morten Stilund, Boris Modrau, A. Strade, Mirko Porobić, Søren Due Andersen, Christina Kruuse, Joakim Ölmestig, Mia Kolmos, Md. Anowar Khasru Parvez, Thomas Christensen, Jakob Stokholm, Henrik Boye Jensen, Jukka Putaala, Daniel Strbian, Gerli Sibolt, Marjaana Tiainen, Nicolas Martinez‐Majander, Sami Curtze, Silja Räty, Yvonn Kraemer, Risto O. Roine, Julia Åivo, Juhani Ruuskanen, Pauli Ylikotila, Susanna Roine, Merja Hallikainen, Pekka Jäkälä, Sudhir Kurl, Valtteri Julkunen, Igor Sibon, Stéphane Olindo, Sébastien Richard, Vincent Larrue, Cédric Gollion, Hélène Catala, Hilde Hénon, D.S. Lucie, D. Nelly, Jean‐Louis Mas, D. Calvet, A. Malbranque, Béatrice Mazé, C. Barbieux-Ghitu, G.H. Pitie Salpetriere, Charlotte Rosso, Yves Samson, Stéphane Vannier, Thierry Moulin, Louise Bonnet, Peggy Reiner, F. Buffon, Christian Denier, K. Amri, Nicolas Legris, O. Chassin, N. Selli, S. Mariana, J. Berrouschot, Anett Stoll, D. Klunk, Janina Keilitz, M. Neustadt, S. Zerrenner, Roland Veltkamp, Karim Hajjar, Allen Heeger, E. Winezki, L. Apel, Mosche Pompsch, Paul S. Mueller, P Rappard, Rebecca C. Auer, Peter A. Ringleb, Anne Berberich, Miriam Heyse, Sibu Mundiyanapurath, Tilman Reiff, Sven Poli, Antonio Gómez‐Expósito, Annerose Mengel, Johannes Tünnerhoff, Kazeem Dauda Adeyemi, Khouloud Poli, V. Kusch, Johann Pelz, Dominik Michalski, Katja E. Wartenberg, Katharina Althaus, Fernando Gomes de Oliveira Tavares, Silvana Mueller, Hassan Soda, A. Rascher, Erich Hiermann, Renate Weinhardt, Karin Weißenborn, Andrei Leotescu, Gerrit M. Große,
Exploratory analysis of the phase 2 PACIFIC-Stroke (Program of Anticoagulation via Inhibition of FXIa by the Oral Compound BAY 2433334-Non-Cardioembolic Stroke) randomized trial suggested that asundexian, an oral factor XIa inhibitor, prevents recurrent stroke and transient ischemic attacks in patients with atherosclerotic stroke. In this post hoc exploratory analysis, we hypothesized that asundexian would be more effective in patients enrolled with large, multiple, or cortical acute infarcts on ...
Lippincott Williams & Wilkins
Paul W. Brandt‐Rauf, Stacieann Yuhasz,
... Liesa Lier Sara Quandt Gregg Stave Jean Cox-Ganser Longtao He Jane Lipscomb Filip Raciborsk Benjamin Steinhilber
Tópico(s): Climate Change and Health Impacts
2022 - Lippincott Williams & Wilkins | Journal of Occupational and Environmental Medicine
Gabriela Alejo, Sidarrth Prasad, Fadar Oliver Otite, Erica Jones, Dileep R. Yavagal, Santiago Ortega‐Gutiérrez, Eric Guemekane Bila Lamou, Shashvat M. Desai, Kaiz Asif, Mehari Gebreyohanns, Peter Bailey, Timothy Kleinig, Dennis Cordato, Philip Choi, Carlos García-Esperón, Andrew Chew, Geoffrey Cloud, Vimal Stanislaus, Maurício Krause, Miriam Priglinger, Rohan Grimley, Darshan Ghia, Ramesh Sahathevan, Henry G. Brown, Chiu‐Yin Kwan, Michael J. Devlin, Stefan Greisenegger, S. Bonelli-Nauer, Jakob Rath, A. Langer, Martha Marko, Jéssica Tonin Ferrari, Alexandra Bernegger, M. Baumgartinger, Matthias Vigl, Stefan Krebs, W. Lang, M. Knoflach, Benjamin Dejakum, Sophia J. Kiechl, Thomas Töll, Lena Domig, Johannes Sebastian Mutzenbach, Bernhard Ganser, Constantin Hecker, Cornelia Rösler, Nele Bubel, Slaven Pikija, Tobias Zellner, Ursula Leitner, Otto Berger, B. Surböck, Sebastian Beirer, Dimitre Staykov, Daniel Schrammel, Altuna Halilović, Michael Frattner, D. Barmherzigen, Christian Lampl, Christopher Hofer, S. Nagl, Christoph Bocksrucker, Jelle Demeestere, P. Desfontaines, C Ciobanu, Adinda De Pauw, Annelies Terwecoren, M.C. Hasenbroekx, C. François, Nina De Klippel, Peter Soors, Sabine Hermans, Sylvie De Raedt, Fenne Vandervorst, Laura Seynaeve, Niels Fockaert, Sofie de Smet, Matthieu Pierre Rutgers, Nicole Del Gaudio, Perrine Paindeville, Ivan Staikov, A. Simeonova, Irina I. Stoyanova, Maria Cholakova, N. Mihnev, T. Petrova, A. Koralova, D. Dimov, Y. Kuzev, Maya Danovska, Diana L. Marinova, D. Marinova-Trifonova, Emilia Ovcharova, Igor Mladenovski, Magdalina Yanakieva, Павел Стоев, Mariya Dimitrova, S. Todorova-Georgieva, L. Haralanov, B. Milkov, D. Solakov, Neli Petkova, V. Ignatova-Valkova, Vesselin Karabinov, Veselina Goranova‐Marinova, Y. Miteva, V. Andonova, D. Kasabova, E. Kostadinova, Y. Shopova-Vrabcheva, D. Gatev, Dimitrina Jivkova Semova, Eray Halil, Ara Kaprelyan, Borko Ivanov, G. Panov, Маргарита Грудкова, N. Syuleyman, R. Kalpachki, Filip Alexiev, I. Ivanova, K. Kancheva, Teodora Sakelarova, Dimitar Maslarov, Desislava Drenska, Vasil Georgiev, Е. Б. Петрова, N. V. Petrova, I. Ivanova, N. Semerdjieva, P. Zhelyazkov, S. Spasova-Markova, Xiaofeng Dong, Daqing Wang, S. Wang, W. Huang, Hui Zhao, C. Wang, Jie Lu, Y. Xinyang, Ping Zhang, Qiang Dong, Yan‐Jiang Wang, Yan Fu-ling, W. Yue, R. Liu, Yanmin Yang, Ivana Štětkářová, Petr Mikulenka, Peter Vaško, Tomáš Peisker, Michal Bar, Martin Roubec, Robert Mikulík, M. Cabukova, Jan Vinklárek, Marek Kovář, M. Pansky, Pavel Mencl, Ondřej Škoda, M. Carek, Marek Pernicka, M Skodová, Petr Geier, Jitka Čepková, Jakub Drlík, Tomáš Prax, R H Herzig, Dagmar Krajíčková, Eva Vítková, Simona Halúsková, Daniel Václavík, J Martínková, K. Blejcharova, M. Tkacova, O. Pavlik, Miroslava Nevšímalová, J. Rosol, Miroslava Nevšímalová, Radovan Hrubý, Helle K. Iversen, A.V. Andersen, D. Rahimi, Hanne Christensen, Josefine Grundtvig, Niels Hjort, Gary L. Andersen, Birgitte Forsom Sandal, Morten Stilund, Boris Modrau, A. Strade, Mirko Porobić, Søren Due Andersen, Christina Kruuse, Joakim Ölmestig, Mia Kolmos, Md. Anowar Khasru Parvez, Thomas M. Christensen, Jakob Stokholm, Henrik Boye Jensen, Jukka Putaala, Daniel Strbian, Gerli Sibolt, Marjaana Tiainen, Nicolas Martinez‐Majander, Sami Curtze, Silja Räty, Yvonn Kraemer, RP Roine, Julia Åivo, Juhani Ruuskanen, Pauli Ylikotila, Susanna Roine, Merja Hallikainen, Pekka Jäkälä, Sudhir Kurl, Valtteri Julkunen, Igor Sibon, Stéphane Olindo, Sébastien Richard, V. Larrue, Cédric Gollion, Hélène Catala, Hilde Hénon, D.S. Lucie, D. Nelly, D. Calvet, A. Malbranque, Béatrice Mazé, C. Barbieux-Ghitu, Charlotte Rosso, Yves Samson, Stéphane Vannier, Thierry Moulin, Louise Bonnet, Peggy Reiner, F. Buffon, Christian Denier, K. Amri, Nicolas Legris, O. Chassin, N. Selli, S. Mariana, J. Berrouschot, Anett Stoll, D. Klunk, Janina Keilitz, M. Neustadt, S. Zerrenner, Roland Veltkamp, Karim Hajjar, Allen Heeger, E. Winezki, L. Apel, Mosche Pompsch, Paul S. Mueller, P Rappard, Rebecca C. Auer, Peter A. Ringleb, Anne Berberich, Miriam Heyse, Sibu Mundiyanapurath, Tilman Reiff, Sven Poli, Antonio Gómez‐Expósito, Annerose Mengel, Johannes Tünnerhoff, Kazeem Dauda Adeyemi, Khouloud Poli, V. Kusch, Johann Pelz, Dominik Michalski, Katja E. Wartenberg, Katharina Althaus, Fernando Gomes de Oliveira Tavares, Silvana Mueller, Hassan Soda, A. Rascher, Erich Hiermann, Renate Weinhardt, Karin Weißenborn, Andrei Leotescu, Gerrit M. Große, Hans Worthmann, Johanna Ernst, Maria M. Gabriel, Ramona Schuppner, Jan Hendrik Schäfer, Daniel Charissé, Kenneth A. Gruber, Natalia Kurka, Sarah C. Reitz, Waltraud Pfeilschifter, J.I. Lee, Michael Gliem, M. Moll,
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