Keishiro Tahara, Yuya Ashihara, Toshiki Higashino, Yoshiki Ozawa, Tomofumi Kadoya, Kunihisa Sugimoto, Akira Ueda, Hatsumi Mori, Masaaki Abe,
Benzothienobenzothiophene (BTBT) and derivatives have received increasing attention as organic field-effect transistor materials and molecular conductors. This report presents the first synthesis of metal complexes involving a BTBT moiety, which was achieved by complexation of 2,2'-bipyridyl complexes of Pt(ii) and Pd(ii) with dihydroxy-substituted BTBT (1) as a new π-extended catecholato ligand (tBu2Bpy = 4,4'-di-tert-butyl-2,2'-dipyridyl). The resulting complexes M(tBu2Bpy)(O2BTBT) (M = Pt (3Pt) and Pd ( ...
Tópico(s): Conducting polymers and applications
2019 - Royal Society of Chemistry | Dalton Transactions
Tomonori Akiyama, Hiroshi Miyamoto, Kazumasa Fukuda, Naoto Sano, Nanako Katagiri, Takeo Shobuike, Akiko Kukita, Yoshio Yamashita, Hatsumi Taniguchi, Masaaki Goto,
The objective of this study was to develop a novel polymerase chain reaction (PCR) method to comprehensively analyze salivary bacterial flora.The bacterial flora in the saliva of 10 healthy persons and 11 patients with odontogenic infections were examined using a DNA extraction method with a high level of cell destruction efficiency and a novel universal primer set to amplify approximately 580 bp of the 16S rDNA sequence.Streptococcus (54.5%), Neisseria (14.7%), Actinomyces (8.4%), Gemella (4.1%), Granulicatella ( ...
Tópico(s): Streptococcal Infections and Treatments
2010 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
Masae Mizoguchi, Hatsumi Naito, Yasushi Kurata, Masaaki Shibata, Hiroyuki Tsuda, Christopher P. Wild, Ruggero Montesano, Shoji Fukushima,
The effects of aging on the multi‐organ Carcinogenesis induced in rats by N‐methyl‐N‐nitrosourea (MNU), a direct carcinogen which does not need metabolic activation to exert carcinogenicity, were examined in male F344 rats. In the first experiment, rats at 6, 52, and 98 weeks of age were treated with MNU (20 mg/kg body weight, i.p.) twice weekly for 6 weeks and then maintained without any further treatment for 24 weeks in the case of young and middle‐aged rats and for 18 weeks in the case of the old ...
Tópico(s): Carcinogens and Genotoxicity Assessment
1993 - Oxford University Press | Japanese Journal of Cancer Research
Hideyo Ugai, Haiou Li, Masaaki Komatsu, Hatsumi Tsutsui, Jun Song, Takashi Shiga, Eric R. Fearon, Takehide Murata, Kazunari K. Yokoyama,
Expression of the DCC (deleted in colorectal cancer) protein is strongly induced during the neural differentiation of mouse P19 embryonal carcinoma (EC) cells that occurs when these cells are treated with retinoic acid (RA). Myc-associated zinc finger protein (MAZ) is a DNA-binding protein that is widely expressed and functions in human, mouse and hamster cells as an activator, an initiator or a terminator of transcription. However, the biological functions of MAZ remain elusive. We report here that ...
Tópico(s): Hippo pathway signaling and YAP/TAZ
2001 - Elsevier BV | Biochemical and Biophysical Research Communications
Mai Sakai, Zhiqian Yu, Ryo Hirayama, Masa Nakasato, Yoshie Kikuchi, Chiaki Ono, Hiroshi Komatsu, Miharu Nakanishi, Hatsumi Yoshii, David Stellwagen, Tomoyuki Furuyashiki, Masaaki Komatsu, Hiroaki Tomita,
Major depressive disorder (MDD) is associated with repeated exposure to environmental stress. Autophagy is activated under various stress conditions that are associated with several diseases in the brain. This study was aimed at elucidating the autophagy signaling changes in the prefrontal cortex (PFC) under repeated social defeat (RSD) to investigate the involvement of microglial autophagy in RSD-induced behavioral changes. We found that RSD stress, an animal model of MDD, significantly induced initial ...
Tópico(s): Autophagy in Disease and Therapy
2022 - Hindawi Publishing Corporation | Neural Plasticity
Kazuyoshi Yoshimi, Masaaki Nakamura, Hatsumi Mori,
We study theoretically competition between the charge ordering and the superconductivity in two-dimensional organic conductor beta-(meso-DMBEDT-TTF)_2PF_6. We analyze the extended Hubbard model on a weakly-dimerized lattice based on the random phase approximation and Eliashberg equations. We found reentrant behavior of the checkerbord-type charge-ordered phase in the phase diagram, and the triplet superconductivity due to the charge fluctuation in the neighboring region. In the low temperature and ...
Tópico(s): Physics of Superconductivity and Magnetism
2007 - Physical Society of Japan | Journal of the Physical Society of Japan
Naoto Sano, Yoshio Yamashita, Kazumasa Fukuda, Hatsumi Taniguchi, Masaaki Goto, Hiroshi Miyamoto,
Intracystic fluid was aseptically collected from 11 patients with postoperative maxillary cyst (POMC), and DNA was extracted from the POMC fluid. Bacterial species were identified by sequencing after cloning of approximately 580 bp of the 16S rRNA gene. Identification of pathogenic bacteria was also performed by culture methods. The phylogenetic identity was determined by sequencing 517-596 bp in each of the 1139 16S rRNA gene clones. A total of 1114 clones were classified while the remaining 25 ...
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2012 - Hindawi Publishing Corporation | ISRN Dentistry
Hatsumi Aki, Masaaki Ohta, Kanji Fukusumi, Yasuhiro Okamoto,
Compatibility between risperidone and soft drinks was examined by means of isothermal titration microcalorimetry, and the interaction of risperidone with tea tannin- (-)-epigallocatechin, (-)-epicatechin, theaflavin and their gallates-was investigated thermodynamically. Risperidone exothermically bound to tea tannin monomers with a binding affinity of 103-104 M-1 in aqueous solution to form an insoluble complex at a 1:1 molar ratio. The binding reaction was characterized by small enthalpy and entropy changes, ...
Tópico(s): Phytochemicals and Antioxidant Activities
2006 - Japanese Society of Pharmaceutical Health Care and Sciences | Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
Masaaki Komatsu, Haiou Li, Hatsumi Tsutsui, Keiichi Itakura, Masatoshi Matsumura, Kazunari K. Yokoyama,
To investigate whether MAZ (Myc-associated zinc finger protein) affects the expression of the c-myc gene during the retinoic acid-induced (RA-induced) neuroectodermal differentiation of P19 embryonal carcinoma (EC) cells, we introduced a CAT reporter construct, human c-myc promoter/CAT (pMyc2CAT), and a mutant CAT derivative that lacked an ME1a1 site (pMyc1CAT) into P19EC cells to monitor the promoter activity of the c-myc gene. The expression of CAT in pMyc2CAT-transformed cells declined fivefold after ...
Tópico(s): RNA Research and Splicing
1997 - Springer Nature | Oncogene
Hiroaki Kawasaki, M. Machida, Masaaki Komatsu, Hai‐Ou Li, Takehide Murata, Hatsumi Tsutsui, Akiko Fujita, Masatoshi Matsumura, Yoshiro Kobayashi, Kazunari Taira, Kazunari K. Yokoyama,
Abstract: Gene therapy based on gene‐specific nucleic acids has moved from theory to a practical possibility in a very short time. The new DNA and RNA therapeutic reagents are intended to stop the growth of cancerous cells or the production of viruses. At the practical level, the efficacy of antisense oligomers as therapeutic reagents has been carefully examined in various clinical contexts. For the efficient use of antisense nucleic acids as pharmaceutical agents, a complete analysis of their mechanisms ...
Tópico(s): Virus-based gene therapy research
1996 - Wiley | Artificial Organs
Masaaki Hatsumi. Telde: Seigan Ediciones, 2005. 191 paginas. 21x14 cm. I.S.B.N.: 84-88738-30-7.
Tópico(s): Cultural and Mythological Studies
2012 - University of León | Revista de artes marciales asiáticas
Masaaki Hatsumi. Telde: Seigan Ediciones, 2000. 164 paginas. 15x24 cm. I.S.B.N.: 84-88738-29-3.
Tópico(s): Ethics and bioethics in healthcare
2012 - University of León | Revista de artes marciales asiáticas
Hirohito Ikeda, Yuri Fukushige, Tomonori Matsubara, Masaaki Inenaga, Mitsunobu Kawahara, Miho Yukawa, Michiko Fujisawa, Eiji Yukawa, Hatsumi Aki,
Tópico(s): Analytical Methods in Pharmaceuticals
2015 - Springer Science+Business Media | Journal of Thermal Analysis and Calorimetry
Hatsumi Inaba, Kyosuke Takeshita, Yasuhiro Uchida, Motoharu Hayashi, Takahiro Okumura, Akihiro Hirashiki, Daiji Yoshikawa, Hideki Ishii, Koji Yamamoto, Takayuki Nakayama, Masaaki Hirayama, Hiroyuki Matsumoto, Tadashi Matsushita, Toyoaki Murohara,
In repetitive measurements of flow-mediated dilatation (FMD), the duration of the interval between measurements remains controversial. In this pilot study, we conducted three sequential measurements of low–flow-mediated constriction (L-FMC), FMD and flow-mediated total dilation (FMTD; L-FMC+ FMD) at baseline and intervals of 15 and 60 min in 30 healthy males. FMD15, L-FMC15, and FMTD15 were significantly lower than the respective first measurements, but all indices showed full recovery at 60 min in ...
Tópico(s): Thermoregulation and physiological responses
2014 - Public Library of Science | PLoS ONE
Tomonori Ohata, Hirohito Ikeda, Masaaki Inenaga, Takeshi Mizobe, Miho Yukawa, Michiko Fujisawa, Hatsumi Aki,
Complex formation between piperazine derivatives (PD) and green tea polyphenols (GTP) in an aqueous solutions and the mechanism were studied by isothermal titration microcalorimetry and molecular modeling study. Lomerizine dihydrochloride (LMZ), cetirizine dihydrochloride (CTZ) and hydroxyzine dihydrochloride (HXZ) were used as PD, and (−)-epigallocatechin gallate (EGCg) and (−)-epigallocatechin (EGC) were used as GTP. The mixed solutions of PD (except HXZ) and EGCg were cloudy because an insoluble complex was ...
Tópico(s): Analytical Chemistry and Chromatography
2017 - Elsevier BV | Thermochimica Acta
Masaaki Shimozawa, K. Hashimoto, Akira Ueda, Yoshitaka Suzuki, K. Sugii, Shota Yamada, Y. Imai, Ryota Kobayashi, K. Itoh, Satoshi Iguchi, M. Naka, Sumio Ishihara, Hatsumi Mori, T. Sasaki, Minoru Yamashita,
Abstract Strongly enhanced quantum fluctuations often lead to a rich variety of quantum-disordered states. Developing approaches to enhance quantum fluctuations may open paths to realize even more fascinating quantum states. Here, we demonstrate that a coupling of localized spins with the zero-point motion of hydrogen atoms, that is, proton fluctuations in a hydrogen-bonded organic Mott insulator provides a different class of quantum spin liquids (QSLs). We find that divergent dielectric behavior ...
Tópico(s): Perovskite Materials and Applications
2017 - Nature Portfolio | Nature Communications
Masaaki Nakamura, Kazuyoshi Yoshimi, Hatsumi Mori,
We study superconductivity mediated by the charge fluctuation in two-dimensional organic conductor β-(meso-DMBEDT-TTF)2PF6. We consider the extended Hubbard model on a weakly dimerized lattice, and solve the Eliashberg equations based on the random phase approximation. We found reentrant behavior of the checkerboard-type charge-ordered phase in the phase diagram, and the triplet superconductivity due to the charge fluctuation in the neighboring region. This results well agree with the experimental ...
Tópico(s): N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
2006 - Elsevier BV | Journal of Magnetism and Magnetic Materials
Kazuyoshi Yoshimi, Masaaki Nakamura, Hatsumi Mori,
Tópico(s): Organometallic Compounds Synthesis and Characterization
2007 - Physical Society of Japan | Journal of the Physical Society of Japan
... 4403(87)80008-0Hiroshi MORIWAKI, Michio NOGAMI, Yuichi HATSUMI, Yoshiro INOUE CHANGE IN GRAIN SIZE DISTRIBUTION IN ...
Tópico(s): Tunneling and Rock Mechanics
1919 - University of Chicago Press | The Journal of Geology
Shinji Oe, Michihiko Shibata, Masaaki Hiura, Hiroshi Mitsuoka, Toru Matsuhashi, Ryoichi Narita, Shintaro Abe, Akinari Tabaru, Kazuhiro Hayashida, Hatsumi Taniguchi, Masaru Harada,
An 80-year-old man was admitted to our hospital with a diagnosis of primary hepatic actinomycosis determined based on a percutaneous aspiration biopsy. The abscesses and state of liquefaction were easily and effectively visualized on contrast-enhanced ultrasonography. Ampicillin/sulbactam was administered; however, lesions of hepatic actinomycosis suddenly infiltrated the diaphragm and right thorax six months later. A drainage tube was inserted into the right thoracic space, and the pleural effusion ...
Tópico(s): Medical Imaging and Pathology Studies
2014 - The Japanese Society of Internal Medicine | Internal Medicine
K. Hashimoto, Masaaki Shimozawa, Minoru Yamashita, Akira Ueda, Hatsumi Mori, T. Sasaki,
Tópico(s): Advanced Condensed Matter Physics
2021 - Cambridge University Press | Bulletin of the American Physical Society
M. Sugawara, Masahiro Fukuda, Ichiro Sakuma, Yutaka Wakasa, Hideaki Funayama, Akira Kondo, Naoki Itabashi, Yasuyuki Maruyama, Takashi Kamiyama, Yasunori Utsunomiya, Akira Yamauchi, Hidenori Yoshii, Hirokazu Yamada, Koichi Mochizuki, Hiroaki Seino, Murata Kaori, Shigeo Yatagai, Hiroshi Koyama, Hareaki Yamamoto, Miho Shimizu, Toshio Kawada, Setsuya Sakagashira, S Ozeki, Tomoo Takeda, Tomohiro Katsuya, Mariko Oishi, K Doniwa, Nobuyuki Ueda, Makiko Sasamoto, Hatsumi Masaki, Takashi Kamiyama, Woon-Joo Lee, Hiroko Chimori, Hiroshi Takeda, Kazuo Ikeda, Hiroaki Nishioka, Kyoko Mitsuhashi, Toru Kinugawa, Motoko Miki, Toshiyuki Horiuchi, Kunihiro Doi, Y. Shinagawa, Isato Shimozono, Jinro Ishizuka, Shun-ichiro Sakurai, Shigeki Moritani, Norio Kase, Shigeru Watanabe, Shinsuke Nakata, Keiko Tsunoda, Tadashi Sawanishi, Yuji Ogawa, Tomokazu Matsuda, Tomohiro Tsuji, Shinichiro Shirabe, Satoshi Ashitomi, H. Ogata, Kaneyuki Matsuo, T Sugie, Ken Takenaka, Asami Tanaka, Yoshiro Suzuki, Masahiro Inoue, Hiroshi Hasegawa, Haruyoshi Nakao, Tetsuo Nishikawa, Mikio Uematsu, Daigaku Uchida, Masaaki Miyakawa, Masahiro Takihata, Hirotaka Ishii, Kenji Mizuno, Masahiko Inomata, K Minamisawa, Soichi Honda, Mitsuo Shirakawa, Katsuya Fuse, Takuji Yamao, Akihiko Nakazima, Masahiro Nagano, Masahiko Nakamura, Suzuko Iwami, Hisakazu Degawa, Naoko Katayanagi, Yoshiharu Okada, Hideaki Sawaki, H. Ogata, Motoshige Miyano, Yuki Matsuda,
Evidence of a direct comparison between dipeptidyl-peptidase 4 inhibitors (DPP-4is) and sodium-glucose cotransporter 2 inhibitors (SGLT2is) remains lacking, and no clear treatment strategy or rationale has been established using these drugs. This study aimed to compare the overall efficacy and safety of DPP-4is and the SGLT2i luseogliflozin in patients with type 2 diabetes mellitus (T2DM).Patients with T2DM who had not used antidiabetic agents or who had used antidiabetic agents other than SGLT2is ...
Tópico(s): Potassium and Related Disorders
2023 - Adis, Springer Healthcare | Diabetes Therapy
Masaaki Shimozawa, Yoshitaka Suzuki, Kaori Sugii, Akira Ueda, Shogo Yamada, Yusuke Imai, Kiyoshi Torizuka, Yoshiya Uwatoko, Hatsumi Mori, Minoru Yamashita,
Tópico(s): Physics of Superconductivity and Magnetism
2016 - Cambridge University Press | Bulletin of the American Physical Society
... 224, 245, 305Kasai, Reo, 6Kassis, Sebouh Z., 150Kato, Hatsumi Yano, 270Kawachi, Shigeyuki, 17, 356Kawamura, Hideki, 345Kawano, Tatsuyuki, ... Ahmet, 288Uchino, Motoi, 210Uchiyama, Shuichiro, 120Ueno, Akihisa, 17Urade, Masaaki, 296Valladares, Héctor, 189Vargas, Gabriela, 363Vicente, Vicente, 203Viehl, Carsten ...
Tópico(s): Esophageal and GI Pathology
2013 - The International College of Surgeons | International Surgery