Toshio Ohhashi, Takahiro Azuma, Masao Sakaguchi,
Pressure-volume and pressure-radius relationships in lymphangions isolated from bovine mesenteric lymphatics were similar in pattern with those in the vein. Circumferential modulus of elasticity of the lymphatics ranged from 4.2 x 10(4) tatic walls. The contractile force increased in early stages of distension and decreased after an optimal intraluminal pressure was attained. The spontaneous activity was also affected by the rate of wall deformation. The pacemaker site of spontaneous activity seemed ...
Tópico(s): Lymphatic Disorders and Treatments
1980 - American Physical Society | AJP Heart and Circulatory Physiology
Toshio Ohhashi, Takahiro Azuma, Masao Sakaguchi,
Spontaneous contractions were elicited by microvibrations (1--80 Hz, 50--400 micron) imposed upon quiescent ureter and portal venous smooth muscles of dogs. The microvibrations increased the rate of spontaneous contractions. A microvibration of larger amplitude gave rise to a more profound increase at each frequency. The acceleration was often accompanied by a reduction in contractile force. The positive chronotropic effect was enhanced by increases in frequency from 20 to 40 Hz and not affected ...
Tópico(s): Nitric Oxide and Endothelin Effects
1979 - American Physical Society | AJP Cell Physiology
Hirofumi Usui, Miki Imazu, Kazuhiro Maeta, Hisao Tsukamoto, K Azuma, Masao Takeda,
Two type 2A protein phosphatases, phosphatases I (Mr = 180,000) and III (Mr = 177,000), were purified to near homogeneity from human erythrocyte cytosol. Phosphatase I was composed of alpha (34 kDa), beta (63 kDa), and delta (74 kDa) subunits in a ratio of 1:1:1. Phosphatase III comprised alpha, beta, and gamma (53 kDa) subunits in the same ratio. Heparin-Sepharose column chromatography converted most of phosphatase I and 20% of phosphatase III into alpha 1 beta 1 which were indistinguishable from phosphatase ...
Tópico(s): Cellular transport and secretion
1988 - Elsevier BV | Journal of Biological Chemistry
Keitaro Kubo, Hiroaki Kanehisa, KASUMI AZUMA, MASAO ISHIZU, Shinya Kuno, Morihiro Okada, Tetsuo Fukunaga,
KUBO, K., H. KANEHISA, K. AZUMA, M. ISHIZU, S.-Y. KUNO, M. OKADA, and T. FUKUNAGA. Muscle Architectural Characteristics in Women Aged 20–79 Years. Med. Sci. Sports Exerc., Vol. 35, No. 1, pp. 39–44, 2003. Purpose The purpose of this study was to investigate the muscle architectural characteristics, i.e., muscle thickness, pennation angle, and fascicle length, in women aged 20–79 yr. Methods A total of 224 sedentary healthy women participated in this study. Muscle thickness and pennation angle of ...
Tópico(s): Ergonomics and Musculoskeletal Disorders
2003 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Jun Shiraishi, Tetsuya Tatsumi, Kazutoshi Shimoo, Asako Katsume, Hiroki Mani, Miyuki Kobara, Takeshi Shirayama, Akihiro Azuma, Masao Nakagawa,
A 59-year-old woman with skin sarcoidosis was admitted to hospital for assessment of complete atrioventricular block. Cross-sectional echocardiography showed that the apical free wall of the right ventricle was thin and dyskinetic with dilation of the right ventricle. Thallium-201 myocardial imaging revealed a normal distribution. Both gallium-67 and technetium-99m pyrophosphate scintigraphy revealed no abnormal uptake in the myocardium. Right ventriculography showed chamber dilation and dyskinesis ...
Tópico(s): Viral Infections and Immunology Research
2003 - Japanese Circulation Society | Circulation Journal
Jun Shiraishi, Tetsuya Tatsumi, Masaki Kimata, Daisuke Kambayashi, Akiko Mano, Satoshi Yamanaka, Miyuki Kobara, Akihiro Azuma, Masao Nakagawa,
Pulmonary vein varix is a rare abnormality, often resembling a pulmonary or mediastinal mass on chest radiographs, and pulmonary angiography has been the mainstay of diagnosis. An unusual case of pulmonary vein varix was clearly defined by echocardiography performed in a 47-year-old woman with chest discomfort who had been found to have an abnormal structure behind the cardiac silhouette on a chest radiograph. The diagnosis of left lower pulmonary vein varix was noninvasively confirmed by transthoracic ...
Tópico(s): Vascular anomalies and interventions
2003 - Japanese Circulation Society | Circulation Journal
Kazuki Ito, Hiroki Sugihara, Shuji Katoh, Akihiro Azuma, Masao Nakagawa,
Tópico(s): Cardiac Imaging and Diagnostics
2003 - Springer Nature | Annals of Nuclear Medicine
Kanae Kubo, Hiroaki Kanehisa, K. Azuma, MASAO ISHIZU, Shinya Kuno, Mitsuhiro Okada, T. Fukunaga,
The purpose of this study was to compare the muscle architectural characteristics, i. e., muscle thickness, pennation angle, fascicle length, of four different groups comprising a total of 121 men and 190 women, divided according to sex and age (i. e., 20 - 39 yrs and 60 - 85 yrs). Muscle thickness and pennation angles of the vastus lateralis (VL), medial gastrocnemius (MG), long head of triceps brachii (TB) muscles were measured by B-mode ultrasonography, and fascicle length was estimated. Men had significantly ...
Tópico(s): Sports Performance and Training
2003 - Thieme Medical Publishers (Germany) | International Journal of Sports Medicine
Kinya Matsubara, Takashi Nakamura, Toshiro Kuribayashi, Akihiro Azuma, Masao Nakagawa,
In patients with apical hypertrophic cardiomyopathy (ApHCM), we estimated the severity of cavity obliteration (CO) in the apical potion of the left ventricle and correlated it with various clinical findings including apical aneurysm. Apical hypertrophic cardiomyopathy sometimes develops apical aneurysm. The apical CO is often exhibited in ApHCM along with apical hypertrophy and ischemia. It remains unclear, however, how the CO and others are related to aneurysm. In 46 patients with ApHCM, we measured ...
Tópico(s): Cardiovascular Function and Risk Factors
2003 - Elsevier BV | Journal of the American College of Cardiology
Arihiko Kanaji, Motomichi Kosuga, Xiao‐Kang Li, Yasuyuki Fukuhara, Akiko Tanabe, Yuko Kamata, Noriyuki Azuma, Masao Yamada, Toyonori Sakamaki, Yoshiaki Toyama, Torayuki Okuyama,
Neonatal gene transfer using adenovirus vectors expressing human beta-glucuronidase (AxCAhGUS) resulted in pathological improvement in multiple visceral organs of mice with mucopolysaccharidosis type VII (MPSVII). However, the therapeutic effect on skeletal deformities and growth retardation, the major clinical symptoms in MPSVII, was not fully investigated by biochemical and histopathological analyses. In this study, we injected AxCAhGUS into a murine model of MPSVII (B6/MPSVII) within 24 h of birth ...
Tópico(s): Virus-based gene therapy research
2003 - Elsevier BV | Molecular Therapy
Kazutoshi Takahashi, Junpei Azuma, Masao Kamada,
We studied the image-potential state (IPS) on a highly oriented pyrolitic graphite surface by means of angle-resolved multiphoton photoemission spectroscopy. The free-electron--like dispersion of IPSs with $n$ = 1, 2, and 3 is observed for the first time with high energy and momentum resolution. From the dependence of the spectral intensity on the excitation density and comparisons with the energy diagram, it is suggested that IPSs are populated by the ${k}_{/\phantom{\rule{-0.16em}{0ex}}/}$-conserved ...
Tópico(s): Electron and X-Ray Spectroscopy Techniques
2012 - American Physical Society | Physical Review B
Kazutoshi Takahashi, Yuji Kondo, Junpei Azuma, Masao Kamada,
A new beamline for high-resolution angle-resolved photoemission study on solids and surfaces has been constructed at BL13 of Saga Light Source. In order to realize high-resolution in a wide energy range, the monochromator system is composed of the grazing-incidence mount with two varied line spacing plane gratings (VLSPG) and the normal incidence mount with a multilayer-coated plane grating. Relatively, high photon flux and low higher-order light can be obtained using the multilayer-coated plane ...
Tópico(s): Advanced Optical Sensing Technologies
2005 - Elsevier BV | Journal of Electron Spectroscopy and Related Phenomena
Hiroshi Azuma, Masao Toyota, Yoshinori Asakawa, Shoichi Kawano,
Ether extracts of petals, gynoecia and leaves of nine Magnolia taxa were analysed using GC-mass spectrometry. The extracts of flowers and gynoecia of five taxa (M. denudata, M. liliiflora, M. tomentosa, M. p. var. praecocissima and var. borealis) contained naphthalene as their main component. The extracts of M. salicifolia characteristically contained several phenylpropanoids including eugenol methyl ether. Two well known sesquiterpene lactones, dehydrocostuslactone and porthenolide, were found in ...
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
1996 - Elsevier BV | Phytochemistry
Tetsuhiro Yamano, Takahisa Sawada, Kenzo Sakamoto, Takeshi Nakamura, Akihiro Azuma, Masao Nakagawa,
A 44-year-old man was referred to hospital for the evaluation of atypical chest pain. His chest X-ray showed leftward displacement of the heart. During echocardiography, the apical window displaced laterally in the usual left lateral position and characteristic motions of the interventricular septum and left ventricular posterior wall were recognized with postural alterations. We presumed a complete absence of the left pericardium. Magnetic resonance imaging (MRI), however, demonstrated a partial ...
Tópico(s): Cardiovascular Effects of Exercise
2004 - Japanese Circulation Society | Circulation Journal
Shin‐ichi Kashiwabara, Sayuri AZUMA, Masao Tsuduki, Yuzuru Suzuki,
The gene that coded for the subunit of an molecular weight (Mr) 540,000 homohexameric alpha-glucosidase II (alpha-D-glucoside glucohydrolase, EC 3.2.1.20) produced by Bacillus thermoamyloliquefaciens KP1071 (FERM-P8477) growing at 30 to 66 degrees C was expressed in Escherichia coli HB101. The resulting homohexameric enzyme had a half-life of 10 min at 80 degrees C. Its purification and characterization showed that the enzyme was identical with the native one except for the latter deleting 7 N-terminal ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2000 - Oxford University Press | Bioscience Biotechnology and Biochemistry
Tomoki Nakamura, Hiroki Sugihara, Noriyuki Kinoshita, Satoshi Yoneyama, Akihiro Azuma, Masao Nakagawa,
Abstract —Although echocardiography is a useful diagnostic tool in hypertrophic cardiomyopathy (HCM), it is sometimes difficult to differentiate it from hypertensive heart disease (HHD): some patients with HCM show symmetrical hypertrophy, whereas patients with HHD sometimes show asymmetrical septal hypertrophy. We used a radioiodinated long-chain fatty acid tracer to visualize the altered myocardial fatty acid metabolism of HCM and HHD. Carnitine is the essential substance for the β-oxidation of long- ...
Tópico(s): Metabolism and Genetic Disorders
2000 - Lippincott Williams & Wilkins | Hypertension
Kazutoshi Takahashi, Masaki Imamura, Isamu Yamamoto, Junpei Azuma, Masao Kamada,
Image potential states (IPSs) on monolayer, bilayer, and trilayer graphene epitaxially grown on SiC(0001) have been studied by time- and angle-resolved two-photon photoemission (2PPE) spectroscopy. The free-electron-like dispersions of even and odd symmetry IPSs with a quantum number of $n$ = 1${}^{+}$, 1${}^{\ensuremath{-}}$, 2, 3 were observed. All observed IPSs showed the dispersions with effective masses of ${m}^{*}=1.0\ifmmode\pm\else\textpm\fi{}0.1{m}_{e}$. The 2PPE intensity of the lowest IPS ($n$ = ...
Tópico(s): Quantum and electron transport phenomena
2014 - American Physical Society | Physical Review B
Heon‐Jung Kim, Ki‐Seok Kim, J.-F. Wang, V.A. Kulbachinskii, K. Ogawa, Minoru Sasaki, Akira Ohnishi, Mamoru Kitaura, Yue Wu, Li Li, Isamu Yamamoto, Junpei Azuma, Masao Kamada, V. Dobrosavljević,
We propose a phase diagram for FexBi2Te3 (0 < x < 0.1) single crystals, which belong to a class of magnetically bulk-doped topological insulators. The evolution of magnetic correlations from ferromagnetic- to antiferromagnetic- gives rise to topological phase transitions, where the paramagnetic topological insulator of Bi2Te3 turns into a band insulator with ferromagnetic-cluster glassy behaviours around x ~ 0.025, and it further evolves to a topological insulator with valence-bond glassy behaviours, which ...
Tópico(s): Magnetic and transport properties of perovskites and related materials
2013 - American Physical Society | Physical Review Letters
Hiroshi Azuma, Masao Toyota, Yoshinori Asakawa,
Tópico(s): Horticultural and Viticultural Research
2001 - Springer Science+Business Media | Journal of Plant Research
Kazuki Ito, Hiroki Sugihara, Tatsuya Kawasaki, Tatsuya Yuba, Tomoki Doue, Takuji Tanabe, Yoshihiko Adachi, Shuji Katoh, Akihiro Azuma, Masao Nakagawa,
Tópico(s): Pericarditis and Cardiac Tamponade
2001 - Springer Nature | Annals of Nuclear Medicine
Hiroshi Azuma, Masao Toyota, Yoshinori Asakawa, Ryohei Yamaoka, José G. García‐Franco, Gregg Dieringer, Leonard B. Thien, Shoichi Kawano,
Abstract Floral scents emitted from Magnolia, Michelia and Liriodendron taxa native to or cultivated in North America, Mexico and Japan were collected by the headspace method and analyzed using gas chromatography – mass spectrometry (GC‐MS). Volatile compounds are widespread in the flowers of angiosperms and the chemical property of the scents can be distinguished in taxa. For example, the primary chemical in the scent of Magnolia virginiana growing in Louisiana (U.S.A.) is linalool, whereas in Maryland ( ...
Tópico(s): Plant biochemistry and biosynthesis
1997 - Wiley | Plant Species Biology
Tomoki Nakamura, Hiroki Sugihara, Tohru Inaba, Noriyuki Kinoshita, Yoshihiko Adachi, Satoshi Hirasaki, Akiko Matsuo, Akihiro Azuma, Masao Nakagawa,
Abstract CD36 is homologous with myocardial long-chain fatty acid (LCFA) binding protein and has been suggested to relate to myocardial fatty acid metabolism. Myocardial scintigraphy with iodine-123 15- ( p -iodophenyl)-3-(R, S)-methylpentadecanoic acid (BMIPP) revealed an impairment in LCFA metabolism chiefly in the hypertrophic myocardium in hypertrophic cardiomyopathy (HCM). Recently, the incidence of CD36 deficiency has been reported to be high in HCM patients, and CD36 deficiency was proposed as an etiology ...
Tópico(s): Cardiac tumors and thrombi
1999 - Elsevier BV | Journal of Molecular and Cellular Cardiology
Shouhei Mine, Takumi Koshiba, Eijiro Honjo, Tomoyuki Okamoto, Taro Tamada, Yoshitake Maeda, Yasuko Matsukura, Akane Horie, Matsujiro Ishibashi, Miharu Sato, Mizue Azuma, Masao Tokunaga, Katsutoshi Nitta, Ryota Kuroki,
The granulocyte colony-stimulating factor receptor (GCSFR), containing the Ig-like domain (Ig) and cytokine receptor homologous region (CRH), was prepared as a preformed dimer (Ig-CRH-Fc)(2) after fusion to the mouse Fc region via an eight-residue linker (approximately 55 A). Monomer Ig-CRH was also prepared after the Fc region was removed from (Ig-CRH-Fc)(2). GCSF binding to Ig-CRH and (Ig-CRH-Fc)(2) was investigated using light scattering and isothermal titration calorimetry. The average molecular mass ...
Tópico(s): T-cell and B-cell Immunology
2004 - American Chemical Society | Biochemistry
Kazuki Ito, Hiroki Sugihara, Tatsuya Kawasaki, Shuji Katoh, Akihiro Azuma, Masao Nakagawa,
Tópico(s): Cardiovascular Function and Risk Factors
2001 - Springer Nature | Annals of Nuclear Medicine
Jun Shiraishi, Yoshiaki Harada, Sumio Komatsu, Yoko Suzaki, Yasuo Hosomi, Shinji Hirano, Takahisa Sawada, Tetsuya Tatsumi, Akihiro Azuma, Masao Nakagawa, Hiroaki Matsubara,
Transthoracic echocardiography is useful for evaluation of the coronary arteries in infants and children with Kawasaki disease. In adults, however, transthoracic echocardiography often cannot detect or accurately estimate coronary artery lesions. We describe two young adults admitted for a diagnosis of acute myocardial infarction ascribed to Kawasaki disease and treated by angioplasty. Coronary aneurysms were not evident in either patient at the time of angioplasty. However, follow‐up transthoracic ...
Tópico(s): Cardiac Structural Anomalies and Repair
2004 - Wiley | Echocardiography
We trained monkeys to make rapid key-release when a tiny light spot dimmed, so that they gazed at the spot until it dimmed. While the animal was performing the gaze task, we recorded unit activity in the prefrontal cortex and found that many neurons increased in discharge rate during the gaze trial (G neuron) with a variety of discharge patterns: many units were activated continuously during the gaze period; others were activated phasically only in an earlier portion of the gaze period. The activation ...
Tópico(s): Retinal Development and Disorders
1977 - Elsevier BV | Brain Research
A glass-coated microelectrode made of a stiff cobalt-nickel alloy is described. The thickness of the glass coating and the length of the uninsulated tip can be varied as desired. The electrode is stiff enough to insert through the relatively tough dura of the monkey in chronic experiments. Further, the recording site can be marked by electrolytic deposition of iron and the Prussian blue reaction. Nous décrivons une microélectrode faite d'un fil d'alliage rigide (Elgiloy) couvert de verre. L'épaisseur ...
Tópico(s): Neural dynamics and brain function
1976 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
Hisao Suzuki, Masao Azuma, H. Yumiya,
Many neurons in the inferior dorsolateral area of the monkey prefrontal cortex showed sustained increases in discharge rates during continuous gazing at a tiny light spot that had a reward significance. These increases might depend upon stimulus factors (light target), behavioral factors (gazing) or both. In this report, we tried to separate these factors and to test the extent to which each factor might contribute to the neuronal reaction.Monkeys were trained to exhibit two kinds of behavior: 1) ...
Tópico(s): Retinal Development and Disorders
1979 - Physiological Society of Japan | The Japanese Journal of Physiology
A continuum approximation is proposed for problems of flows in large and dense networks, where each point of the continuum is characterized by ‘capacity’ and/or ‘distance/cost’ which are convex sets in the tangent space. The problems of flows in continua corresponding to various problems of flows in networks are formulated in variational forms, of which mathematical properties are investigated and for which numerical algorithms are derived by means of the finite-element discretization technique. A ...
Tópico(s): Evacuation and Crowd Dynamics
1982 - Springer Nature | Mathematical programming studies
Tópico(s): Retinal Development and Disorders
1983 - Springer Science+Business Media | Experimental Brain Research