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Tópico(s): Biblical Studies and Interpretation
1962 - Oxford University Press | The Journal of Theological Studies
Bronner P. Gonçalves, Simon R. Procter, Proma Paul, Jaya Chandna, Alex Lewin, Farah Seedat, Artemis Koukounari, Ziyaad Dangor, Shannon Leahy, Sridhar Santhanam, Hima B. John, Justina Bramugy, Azucena Bardají, Amina Abubakar, Carophine Nasambu, Romina Libster, Clara Sánchez Yanotti, Erzsébet Horváth‐Puhó, Henrik Toft Sørensen, Diederik van de Beek, Merijn W. Bijlsma, William M. Gardner, Nicholas J Kassebaum, Caroline Trotter, Quique Bassat, Shabir A. Madhi, Philipp Lambach, Mark Jit, Joy E. Lawn, Kirstine K. Søgaard, Merel N van Kassel, Linde Snoek, Brechje de Gier, Arie van der Ende, Susan Hahné, Lois M. Harden, Azra Ghoor, Sibongile Mbatha, Sarah Lowick, Barbara Laughton, Tamara Jaye, Sanjay G. Lala, Pamela Sithole, Jacqueline Msayi, Ntombifuthi Kumalo, Tshepiso Msibi, Asha Arumugam, Nandhini Murugesan, Nandhini Rajendraprasad, Mohana Priya, Adam Mabrouk, Patrick V. Katana, Eva Mwangome, Charles R. Newton, Humberto Mucasse, Céline Aerts, Sérgio Massora, Valeria Medina, Andrea Rojas, Daniel Miele Amado, Conrado J. Llapur, Ahmed Hossain, Qazi Sadeq-ur Rahman, Margaret Ip, Anna C. Seale, Paul T. Heath, Kirsty Le Doaré, Asma Khalil, Stephanie J. Schrag, Ajoke Sobanjo-ter Meulen, Elizabeth Mason, Dianna M. Blau, Shams El Arifeen, Nega Assefa, Dickens Onyango, Samba O. Sow, Inácio Mandomando, Ikechukwu U. Ogbuanu, Karen L. Kotloff, J. Anthony G. Scott, Emily S. Gurley, Beth A. Tippet Barr, Sana Mahtab,
Group B streptococcus (GBS) colonisation during pregnancy can lead to invasive GBS disease (iGBS) in infants, including meningitis or sepsis, with a high mortality risk. Other outcomes include stillbirths, maternal infections, and prematurity. There are data gaps, notably regarding neurodevelopmental impairment (NDI), especially after iGBS sepsis, which have limited previous global estimates. In this study, we aimed to address this gap using newly available multicountry datasets.
Tópico(s): Maternal and Neonatal Healthcare
2022 - Elsevier BV | The Lancet Global Health
Irnanda Aiko Fifi Djuuna, Saraswati Prabawardani, Maria Massora,
Phosphorus (P) is an essential macronutrient for plant growth and is mainly present in agricultural soil in unavailable forms. Phosphate-solubilizing microorganisms (PSMs) increase soil P availability. The objective of the present study was to assess the population and type of PSMs and their relationships with soil characteristics in the agricultural soil of Manokwari. Twenty-one composite soil samples (0-20 cm) were collected at the rhizospheres of plants in the Prafi and Masni Districts. A dilution ...
Tópico(s): Plant Growth and Agriculture Techniques
2022 - Japanese Society Of Microbial Ecology | Microbes and Environments
Augusto Messa, Pamela C. Köster, Marcelino Garrine, Carol A. Gilchrist, Luther A. Bartelt, Tacilta Nhampossa, Sérgio Massora, Karen L. Kotloff, Myron M. Levine, Pedro L. Alonso, David Carmena, Inácio Mandomando,
Giardia duodenalis is an enteric parasite commonly detected in children. Exposure to this organism may lead to asymptomatic or symptomatic infection. Additionally, early-life infections by this protozoan have been associated with impaired growth and cognitive function in poor resource settings. The Global Enteric Multicenter Study (GEMS) in Mozambique demonstrated that G . duodenalis was more frequent among controls than in diarrhoeal cases (≥3 loosing stools in the previous 24 hours). However, no molecular ...
Tópico(s): Parasites and Host Interactions
2021 - Public Library of Science | PLoS neglected tropical diseases
Inácio Mandomando, Delfino Vubil, Nadia Boisen, Llorenç Quintó, Joaquı́m Ruiz, Betuel Sigaúque, Tacilta Nhampossa, Marcelino Garrine, Sérgio Massora, Pedro Aíde, Ariel Nhacolo, María J. Pons, Quique Bassat, Jordi Vilà, Eusébio Macete, Flemming Scheutz, Myron M. Levine, Fernando Ruı́z-Pérez, James P. Nataro, Pedro L. Alonso,
Multidrug-resistant Escherichia coli ST131 fimH30 responsible for extra-intestinal pathogenic (ExPEC) infections is globally distributed. However, the occurrence of a subclone fimH27 of ST131 harboring both ExPEC and enteroaggregative E. coli (EAEC) related genes and belonging to commonly reported O25:H4 and other serotypes causing bacteremia in African children remain unknown. We characterized 325 E. coli isolates causing bacteremia in Mozambican children between 2001 and 2014 by conventional multiplex ...
Tópico(s): Viral gastroenteritis research and epidemiology
2020 - Public Library of Science | PLoS neglected tropical diseases
Keith P. Klugman, Gail L. Rodgers,
... prevalence of 20·7%.8Sigauque B Moiane B Massora S et al.Early declines in vaccine type ...
Tópico(s): Bacterial Infections and Vaccines
2019 - Elsevier BV | The Lancet
Lola Madrid, Aina Casellas, Charfudin Sacoor, Llorenç Quintó, António Sitoe, Rosauro Varo, Sozinho Acácio, Tacilta Nhampossa, Sérgio Massora, Betuel Sigaúque, Inácio Mandomando, Simon Cousens, Clara Menéndez, Pedro L. Alonso, Eusébio Macete, Quique Bassat,
Although the burden of postdischarge mortality (PDM) in low-income settings appears to be significant, no clear recommendations have been proposed in relation to follow-up care after hospitalization. We aimed to determine the burden of pediatric PDM and develop predictive models to identify children who are at risk for dying after discharge.Deaths after hospital discharge among children aged <15 years in the last 17 years were reviewed in an area under demographic and morbidity surveillance in Southern ...
Tópico(s): Food Security and Health in Diverse Populations
2018 - American Academy of Pediatrics | PEDIATRICS
Tolulope Adebanjo, Fernanda C. Lessa, Hélio Mucavele, Benild Moiane, Alberto Chaúque, Fabiana Cristina Pimenta, Sérgio Massora, María da Gloria Carvalho, Cynthia G. Whitney, Betuel Sigaúque,
Background Pneumococcal colonization is a precursor to pneumonia, and pneumococcal conjugate vaccines (PCV) can decrease vaccine-type (VT) colonization. Pneumococcal colonization studies are traditionally done among healthy children in the community; however, VT colonization prevalence may differ between these children and those with pneumonia. We assessed overall and VT pneumococcal colonization and factors associated with colonization among children with and without pneumonia after Mozambique introduced ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2018 - Public Library of Science | PLoS ONE
Jennifer R. Verani, Sérgio Massora, Sozinho Acácio, R. Santos, Delfino Vubil, Fabiana Cristina Pimenta, Iaci Moura, Cynthia G. Whitney, Maria Helena Costa, Eusébio Macete, Maria Benigna Matsinhe, María da Gloria Carvalho, Betuel Sigaúque,
Nasopharyngeal carriage is a precursor for pneumococcal disease and can be useful for evaluating pneumococcal conjugate vaccine (PCV) impact. We studied pre-PCV pneumococcal carriage among HIV-infected and -uninfected children in Mozambique. Between October 2012 and March 2013, we enrolled HIV-infected children age <5 years presenting for routine care at seven HIV clinics in 3 sites, including Maputo (urban-south), Nampula (urban-north), and Manhiça (rural-south). We also enrolled a random sample of HIV- ...
Tópico(s): Respiratory viral infections research
2018 - Public Library of Science | PLoS ONE
Betuel Sigaúque, Benild Moiane, Sérgio Massora, Fabiana Cristina Pimenta, Jennifer R. Verani, Hélio Mucavele, Alberto Chaúque, Llorenç Quintó, R. Santos, María da Gloria Carvalho, Cynthia G. Whitney, Fernanda C. Lessa,
Background: Pneumococcal carriage is a precursor of invasive pneumococcal disease. Mozambique introduced 10-valent pneumococcal conjugate vaccine (PCV10) in April 2013, using a 3-dose schedule without a booster. We evaluated PCV10 impact on pneumococcal carriage and colonization density by HIV status. Methods: We conducted 2 cross-sectional surveys (pre and post PCV10 introduction) among children 6 weeks to 59 months old. Participants included HIV-infected children presenting for routine care at outpatient ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2018 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Betuel Sigaúque, Miwako Kobayashi, Delfino Vubil, Ariel Nhacolo, Alberto Chaúque, Benild Moaine, Sérgio Massora, Inácio Mandomando, Tacilta Nhampossa, Quique Bassat, Fabiana Cristina Pimenta, Clara Menéndez, María da Gloria Carvalho, Eusébio Macete, Stephanie J. Schrag,
Background Maternal group B streptococcal (GBS) vaccines under development hold promise to prevent GBS disease in young infants. Sub-Saharan Africa has the highest estimated disease burden, although data on incidence and circulating strains are limited. We described invasive bacterial disease (IBD) trends among infants <90 days in rural Mozambique during 2001–2015, with a focus on GBS epidemiology and strain characteristics. Methods Community-level birth and mortality data were obtained from Manhiça' ...
Tópico(s): Pneumonia and Respiratory Infections
2018 - Public Library of Science | PLoS ONE
Emma Sáez-López, Anélsio Cossa, Rachid Benmessaoud, Lola Madrid, Cinta Moraleda, Sonia Villanueva, H. Tligui, Benilde Moiane, Hassan El Alami, Sérgio Massora, Rachid Bezad, Inácio Mandomando, Jordi Bosch, Jordi Vilà, Quique Bassat, Sara M. Soto,
The relevance of vaginal colonization of pregnant women by Escherichia coli is poorly understood, despite these strains sharing a similar virulence profile with other extraintestinal pathogenic E. coli producing severe obstetric and neonatal infections. We characterized the epidemiology, antimicrobial susceptibility and virulence profiles of 84 vaginal E. coli isolates from pregnant women from Rabat (Morocco) and Manhiça (Mozambique), two very distinct epidemiological settings. Low levels of antimicrobial ...
Tópico(s): Escherichia coli research studies
2016 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Miguel J. Martínez, Sérgio Massora, Inácio Mandomando, Esperança Ussene, Dércio Jordão, Lucília Lovane, Carmen Muñoz‐Almagro, Paola Castillo, Alfredo Mayor, Cristina Leal Rodríguez, Miriam Lopez-Villanueva, Mamudo R. Ismail, Carla Carrilho, Cesaltina Lorenzoni, Marcus Lacerda, Quique Bassat, Clara Menéndez, Jaume Ordï, Jordi Vilà,
In developing countries, the knowledge of the microorganisms causing fatal infections is critical and could help designing and implementing more effective preventive interventions and treatment guidelines. We aimed to develop and validate protocols for microbiological analysis in post-mortem samples obtained during minimally invasive autopsy (MIA) procedures and to assess their performance. Thirty MIAs performed in adults at Maputo Central Hospital in Southern Mozambique were included in the analysis. ...
Tópico(s): Data-Driven Disease Surveillance
2015 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Inácio Mandomando, Quique Bassat, Betuel Sigaúque, Sérgio Massora, Llorenç Quintó, Sozinho Acácio, Tacilta Nhampossa, Delfino Vubil, Marcelino Garrine, Eusébio Macete, Pedro Aíde, Charfudin Sacoor, Laura Herrera, Joaquı́m Ruiz, Sharon M. Tennant, Clara Menéndez, Pedro L. Alonso,
Background. Invasive nontyphoidal Salmonella (iNTS) has emerged as a cause of bacteremia in African children and HIV-infected adults, which is associated with high mortality. Epidemiological data and burden of iNTS infections in resource-constrained settings are needed to better define preventive and curative strategies. Methods. Blood and, if appropriate, cerebrospinal fluid, were collected from children <15 years of age with fever or severe disease admitted to the Manhiça District Hospital and cultured ...
Tópico(s): Antibiotic Resistance in Bacteria
2015 - Oxford University Press | Clinical Infectious Diseases
Marcelino Garrine, Glória Matambisso, Nélio Nobela, Delfino Vubil, Sérgio Massora, Sozinho Acácio, Tacilta Nhampossa, Pedro L. Alonso, Inácio Mandomando,
Diarrheagenic Escherichia coli (DEC) are among the leading pathogens associated with endemic diarrhea in low income countries. Yet, few epidemiological studies have focused the contribution of enterohemorrhagic E. coli (EHEC), enteroinvasive E. coli (EIEC) and diffusely adherent E. coli (DAEC).We assessed the contribution of EHEC, EIEC and DAEC isolated from stool samples from a case-control study conducted in children aged < 5 years in Southern Mozambique between December 2007 and November 2012. The ...
Tópico(s): Vibrio bacteria research studies
2020 - BioMed Central | BMC Infectious Diseases
Sandra J Valenciano, Benild Moiane, Fernanda C. Lessa, Alberto Chaúque, Sérgio Massora, Fabiana Cristina Pimenta, Hélio Mucavele, Jennifer R. Verani, María da Gloria Carvalho, Cynthia G. Whitney, Nelson Tembe, Betuel Sigaúque,
Abstract Background Mozambique introduced 10-valent pneumococcal conjugate vaccine (PCV10) in 2013 with doses at ages 2, 3, and 4 months and no catch-up or booster dose. We evaluated PCV10 impact on the carriage of vaccine-type (VT), non-VT, and antimicrobial non-susceptible pneumococci 3 years after introduction. Methods We conducted cross-sectional carriage surveys among HIV-infected and HIV-uninfected children aged 6 weeks to 59 months: 1 pre-PCV10 (2012–2013 [Baseline]) and 2 post-PCV10 introductions ( ...
Tópico(s): Respiratory viral infections research
2020 - Oxford University Press | Journal of the Pediatric Infectious Diseases Society
Betuel Sigaúque, Jennifer R. Verani, Sérgio Massora, Delfino Vubil, Llorenç Quintó, Sozinho Acácio, Inácio Mandomando, Quique Bassat, Tacilta Nhampossa, Fabiana Cristina Pimenta, Charfudin Sacoor, María da Gloria Carvalho, Eusébio Macete, Pedro L. Alonso,
Background Invasive pneumococcal disease (IPD) is a major cause of illness and death among children worldwide. 10-valent pneumococcal conjugate vaccine (PCV10) was introduced as part of the Mozambican routine immunization program in April 2013. We characterized the IPD burden in a rural area of Mozambique before PCV introduction and estimated the potential impact of this intervention. Methods We conducted population-based surveillance for IPD, defined as S. pneumoniae isolated from blood or cerebrospinal ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2018 - Public Library of Science | PLoS ONE
Proma Paul, Jaya Chandna, Simon R. Procter, Ziyaad Dangor, Shannon Leahy, Sridhar Santhanam, Hima B. John, Quique Bassat, Justina Bramugy, Azucena Bardají, Amina Abubakar, Carophine Nasambu, Romina Libster, Clara Sánchez Yanotti, Farah Seedat, Erzsébet Horváth‐Puhó, Ahmed Hossain, Qazi Sadeq-ur Rahman, Mark Jit, Charles R. Newton, Kate Milner, Bronner P. Gonçalves, Joy E. Lawn, Shabir A. Madhi, Ziyaad Dangor, Shannon Leahy, Lois M. Harden, Azra Ghoor, Sibongile Mbatha, Sarah Lowick, Barbara Laughton, Tamara Jaye, Sanjay G. Lala, Pamela Sithole, Jacqueline Msayi, Ntombifuthi Kumalo, Tshepiso Msibi, Sridhar Santhanam, Hima B. John, Asha Arumugam, Nandhini Murugesan, Nandhini Rajendraprasad, Mohana Priya, Amina Abubakar, Carophine Nasambu, Adam Mabrouk Adan, Patrick V. Katana, Eva Mwangome, Charles R. Newton, Quique Bassat, Azucena Bardají, Justina Bramugy, Humberto Mucasse, Céline Aerts, Sérgio Massora, Romina Libster, Clara Sánchez Yanotti, Valeria Medina, Andrea Rojas, Daniel Miele Amado, Conrado J. Llapur, Ahmed Hossain, Qazi Sadeq-ur Rahman,
Data are limited regarding long-term consequences of invasive GBS (iGBS) disease in early infancy, especially from low- and middle-income countries (LMIC) where most cases occur. We aimed to estimate risk of neurodevelopmental impairment (NDI) in children with a history of iGBS disease.
Tópico(s): Bacterial Infections and Vaccines
2022 - Elsevier BV | EClinicalMedicine
Alberto L. García‐Basteiro, Juan Carlos Hurtado, Paola Castillo, Fabiola Fernandes, Mireia Navarro, Lucília Lovane, Isaac Casas, Llorenç Quintó, Dércio Jordão, Mamudo R. Ismail, Cesaltina Lorenzoni, Carla Carrilho, Ariadna Sanz, Natalia Rakislova, Áurea Mira, Míriam J. Álvarez-Martínez, Anélsio Cossa, Frank Cobelens, Inácio Mandomando, Jordi Vilà, Quique Bassat, Clara Menéndez, Jaume Ordï, Miguel J. Martínez,
... 10e01Crossref Scopus (56) Google Scholar,9Martínez M.J. Massora S. Mandomando I. et al.Infectious cause of ...
Tópico(s): Tuberculosis Research and Epidemiology
2020 - Elsevier BV | CHEST Journal
Jaya Chandna, Wan-Hsin Liu, Ziyaad Dangor, Shannon Leahy, Sridhar Santhanam, Hima B. John, Humberto Mucasse, Quique Bassat, Azucena Bardají, Amina Abubakar, Carophine Nasambu, Charles R. Newton, Clara Sánchez Yanotti, Romina Libster, Kate Milner, Proma Paul, Joy E. Lawn, Shabir A. Madhi, Di Zhu, Suk Ling, Lois M. Harden, Azra Ghoor, Sibongile Mbatha, Sarah Lowick, Tamara Jaye, Sanjay G. Lala, Pamela Sithole, Jacqueline Msayi, Ntombifuthi Kumalo, Tshepiso Msibi, S S, Jun Heo, Asha Arumugam, Nandhini Murugesan, Nandhini Rajendraprasad, Mohana Priya, A A, C N, Adam Mabrouk Adan, Patrick V. Katana, Eva Mwangome, Chandini Raj S. N., Q B, Azucena Bardají, Justina Bramugy, H M, Sérgio Massora, Syeda Laila Rubab, Cui Y, Valeria Medina, Andrea Rojas, Daniel Miele Amado, Conrado J. Llapur, Ахметова К.М.,
Survivors of invasive group B Streptococcus (iGBS) disease, notably meningitis, are at increased risk of neurodevelopmental impairment. However, the limited studies to date have a median follow-up to 18 months and have mainly focused on moderate or severe neurodevelopmental impairment, with no previous studies on emotional-behavioral problems among iGBS survivors.In this multicountry, matched cohort study, we included children aged 18 months to 17 years with infant iGBS sepsis and meningitis from ...
Tópico(s): Pneumonia and Respiratory Infections
2021 - Oxford University Press | Clinical Infectious Diseases
Lola Madrid, Sonia Maculuve, Alba Vilajeliu, Emma Sáez-López, Sérgio Massora, Anélsio Cossa, Rosauro Varo, António Sitoe, Noraida Mosqueda, Rui Anselmo, Khátia Munguambe, Sara M. Soto, Cinta Moraleda, Eusébio Macete, Clara Menéndez, Quique Bassat,
In low-income countries, data on prevalence and effects of group B Streptococcus (GBS) and Escherichia coli (E. coli) colonization among pregnant women are scarce, but necessary to formulate prevention strategies. We assessed prevalence of GBS and E. coli colonization and factors associated among pregnant women, its effect in newborns and acceptability regarding the utilized sampling methods in a semirural Mozambican hospital.Pregnant women were recruited from June 2014 to January 2015, during routine ...
Tópico(s): Pneumonia and Respiratory Infections
2018 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Lucía Pastor, Jost Langhorst, Dorit Schröder, Aina Casellas, Andreas Rüffer, Jorge Carrillo, Víctor Urrea, Sérgio Massora, Inácio Mandomando, Julià Blanco, Denise Naniche,
Introduction Primary HIV infection (PHI) is the initial phase after HIV acquisition characterized by high viral replication, massive inflammatory response and irreversible immune-damage, particularly at the gastrointestinal level. In this study we aimed to characterize the dynamics of gastrointestinal damage biomarkers during the different phases of HIV infection and assess their association with HIV-disease markers and their accuracy to differentiate PHI from chronic HIV infection (CHI). Methods ...
Tópico(s): Cytomegalovirus and herpesvirus research
2019 - Public Library of Science | PLoS ONE
Tópico(s): Historical Linguistics and Language Studies
1990 - Société Asiatique | Journal Asiatique
Justina Bramugy, Humberto Mucasse, Sérgio Massora, Pio Vitorino, Céline Aerts, Inácio Mandomando, Proma Paul, Jaya Chandna, Farah Seedat, Joy E. Lawn, Azucena Bardají, Quique Bassat,
Invasive group B Streptococcus disease (iGBS) in infancy, including meningitis or sepsis, carries a high risk of mortality and neurodevelopmental impairment (NDI). We present data on iGBS from 2 decades of surveillance in Manhiça, Mozambique, with a focus on NDI.Morbidity surveillance databases in a rural Mozambican district hospital were screened for iGBS cases. From February 2020 to March 2021, surviving iGBS patients (n = 39) plus age- and sex-matched children without iGBS (n = 119) were assessed for ...
Tópico(s): Maternal and Neonatal Healthcare
2021 - Oxford University Press | Clinical Infectious Diseases
Lucília Lovane, Miguel J. Martínez, Sérgio Massora, Inácio Mandomando, Esperança Ussene, Dércio Jordão, Paola Castillo, Mamudo R. Ismail, Cesaltina Lorenzoni, Carla Carrilho, Quique Bassat, Clara Menéndez, Jaume Ordï, Jordi Vilà, Sara M. Soto,
Introduction: Typhoid fever is an important public health problem in many low-income countries where asymptomatic carriers play an important role in its dissemination. The bacterium causing typhoid fever can live in the gallstones of asymptomatic persons after the infection. These carriers are reservoirs of S. Typhi, are highly contagious, and spread the disease through the secretion of bacteria in feces and urine. The aim of this study was to determine the carrier rate in an area of Mozambique. ...
Tópico(s): Trace Elements in Health
2016 - Open Learning on Enteric Pathogens | The Journal of Infection in Developing Countries
Marcelino Garrine, Sofia Santos Costa, Augusto Messa, Sérgio Massora, Delfino Vubil, Sozinho Acácio, Tacilta Nhampossa, Quique Bassat, Inácio Mandomando, Isabel Couto,
Staphylococcus aureus is one of the main causes of bacteraemia, associated with high mortality, mainly due to the occurrence of multidrug resistant (MDR) strains. Data on antibiotic susceptibility and genetic lineages of bacteraemic S. aureus are still scarce in Mozambique. The study aims to describe the antibiotic susceptibility and clonality of S. aureus isolated from blood cultures of children admitted to the Manhiça District Hospital over two decades (2001-2019).A total of 336 S. aureus isolates ...
Tópico(s): Bacterial biofilms and quorum sensing
2023 - Frontiers Media | Frontiers in Microbiology
Arsénia J. Massinga, Marcelino Garrine, Augusto Messa, Nélio Nobela, Nadia Boisen, Sérgio Massora, Anélsio Cossa, Rosauro Varo, António Sitoe, Juan Carlos Hurtado, Jaume Ordï, Hélio Mucavele, Tacilta Nhampossa, Robert F. Breiman, Cynthia G. Whitney, Dianna M. Blau, Quique Bassat, Inácio Mandomando,
Abstract Background Klebsiella spp. are important pathogens associated with bacteremia among admitted children and is among the leading cause of death in children < 5 years in postmortem studies, supporting a larger role than previously considered in childhood mortality. Herein, we compared the antimicrobial susceptibility, mechanisms of resistance, and the virulence profile of Klebsiella spp. from admitted and postmortem children. Methods Antimicrobial susceptibility and virulence factors of Klebsiella ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2021 - BioMed Central | BMC Infectious Diseases
Filomena Manjate, Llorenç Quintó, Percina Chirinda, Sozinho Acácio, Marcelino Garrine, Delfino Vubil, Tacilta Nhampossa, Eva D. João, Arsénio Nhacolo, Anélsio Cossa, Sérgio Massora, Gizela Bambo, Quique Bassat, Karen L. Kotloff, Myron M. Levine, Pedro L. Alonso, Jacqueline E. Tate, Umesh D. Parashar, Jason M. Mwenda, Inácio Mandomando,
Rotavirus vaccine (Rotarix®) was introduced in Mozambique through its Expanded Program of Immunization in September 2015. We assessed the impact of rotavirus vaccination on childhood gastroenteritis-associated hospitalizations post-vaccine introduction in a high HIV prevalence rural setting of southern Mozambique. We reviewed and compared the trend of hospitalizations (prevalence) and incidence rates of acute gastroenteritis (AGE), and rotavirus associated-diarrhea (laboratory confirmed rotavirus) in ...
Tópico(s): Hepatitis Viruses Studies and Epidemiology
2022 - Elsevier BV | Vaccine
Sérgio Massora, Fernanda C. Lessa, Benild Moiane, Fabiana Cristina Pimenta, Hélio Mucavele, Alberto Chaúque, Anélsio Cossa, Jennifer R. Verani, Nelson Tembe, María da Gloria Carvalho, Carmen Muñoz‐Almagro, Betuel Sigaúque,
Invasive pneumococcal disease (IPD) is a significant cause of morbidity and mortality among children worldwide. In April 2013, Mozambique introduced 10-valent PCV (PCV10) into the National Expanded Program on immunization using a three-dose schedule at 2, 3, and 4 months of age. We aimed to evaluate the invasive disease potential of pneumococcal serotypes among children in our region before and after PCV10 introduction. We used data from ongoing population-based surveillance for IPD and cross-sectional ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2019 - Elsevier BV | Vaccine
Achmad Hussein Sundawa Kartamihardja, Stepanus Massora,
The influence of antithyroid drugs (ATDs) on the therapeutic efficacy of radioactive iodine in hyperthyroidism is still controversial. The aim of this study was to evaluate the effect of ATD discontinuation to the therapeutic efficacy of I-131 in hyperthyroidism patients with long-term ATD treatment. Retrospective study was done to 39 subjects with hyperthyroidism who had been treated with doses of 300 MBq radioactive iodine. The subjects were divided into three groups: Group I (n = 14) had been using ...
Tópico(s): Pituitary Gland Disorders and Treatments
2015 - Thieme Medical Publishers (Germany) | World Journal of Nuclear Medicine