Uwe Zeymer, Peter Ludman, Nicolas Danchin, Petr Kala, Cécile Laroche, Masoumeh Sadeghi, Roberto Caporale, Sameh Mohamed Shaheen, Jacek Legutko, Zaza Iakobsishvili, Khalid F. AlHabib, Zuzana Moťovská, Martin Studenčan, Jorge Mimoso, Dávid Becker, Dimitrios Alexopoulos, Zviad Kereseselidze, Siniša Stojković, Parounak Zelveian, A Goda, Erkin М Мirrakhimov, Gani Bajraktari, Hasan Ali Farhan, Pranas Šerpytis, Bent Raungaard, Toomas Marandi, Alice Moore, Martin Quinn, Pasi P. Karjalainen, Gabriel Tatu-Chitolu, Chris P Gale, Aldo P. Maggioni, Franz Weidinger, Franz Weidinger, Uwe Zeymer, Nicolas Danchin, Peter Ludman, Peter Sinnaeve, Petr Kala, Roberto Ferrari, Aldo P. Maggioni, A Goda, Parounak Zelveian, Franz Weidinger, Kiril Karamfilov, Zuzana Moťovská, Uwe Zeymer, Bent Raungaard, Toomas Marandi, Sameh Mohamed Shaheen, Rosa-María Lidón, Pasi P. Karjalainen, Zviad Kereselidze, Dimitrios Alexopoulos, Dávid Becker, Martin Quinn, Zaza Iakobishvili, Hasan Ali Farhan, Masoumeh Sadeghi, Roberto Caporale, Erkin М Мirrakhimov, Pranas Šerpytis, Andrejs Ērglis, Saško Kedev, Alice Moore, Dariusz Dudek, Jacek Legutko, Jorge Mimoso, Gabriel Tatu-Chiţoiu, Siniša Stojković, Е. V. Shlyakhto, Khalid F. AlHabib, Matjaž Bunc, Martin Studenčan, Mohamed Sami Mourali, Gani Bajraktari, Marème Konté, Florian Larras, Elin Folkesson Lefrancq, Souad Mekhaldi, Cécile Laroche, Aldo P. Maggioni, A Goda, Naltin Shuka, E Pavli, E Tafaj, Taulant Gishto, Alban Dibra, Arvi Duka, A Gjana, Aleksandra S. Kristo, G Knuti, Aurel Demiraj, E Dado, Endri Hasimi, Leonard Simoni, M Siqeca, Hamayak Sisakian, Hamlet Hayrapetyan, S. A. Markos’yan, L Galustyan, N Arustamyan, H Kzhdryan, Sergey Pepoyan, A Zirkik, Dirk von Lewinski, S Paetzold, I Kienzl, K Mátyás, Thomas Neunteufl, Mariam Nikfardjam, U Neuhold, A Mihalcz, F Glaser, Clemens Steinwender, Christian Reiter, Michael Grund, Dragan Hrnčić, Uta C. Hoppe, Matthias Hammerer, Lynne Hinterbuchner, Christian Hengstenberg, Georg Delle Karth, Iréne Lang, Franz Weidinger, W. Winkler, Matthias Hasun, Johannes Kästner, C. Havel, Michael Derntl, G Oberegger, Johannes Hajos, Christopher Adlbrecht, T. Publig, M-C Leitgeb, R Wilfing, Peter Jirak, Carolyn Y. Ho, L Puskas, Lore Schrutka, Jindřich Špinar, Jiří Pařenica, Ota Hlinomaz, V Fendrychova, Jiří Seménka, J Sikora, Jan Sitar, Ladislav Groch, M Rezek, M Novák, P Kramarikova, Josef Šťásek, J Dušek, Petr Zdráhal, Rostislav Polášek, Jiří Karásek, Jiří Seiner, N Sukova, Ivo Varvařovský, Tomáš Lazarák, Vojtěch Novotný, Jan Matějka, Richard Rokyta, Štefan Volovár, Jan Bělohlávek, Zuzana Moťovská, Michal Širanec, M Kamenik, R Kralik, Bent Raungaard, Jan Ravkilde, Svend Eggert Jensen, Anton Boel Villadsen, K Villefrance, Charlotte Schmidt Skov, Michael Mæng, K Moeller, Hosam Hasan‐Ali, Tarek Ahmed, M Hassan, Ahmed ElGuindy, M Farouk Ismail, A Ibrahim Abd El-Aal, Ahmed Gaafar, Hasnita Hassan, Mohammad Shafie, M Elkhouly, Ahmed Bendary, M Darwish, Yesuf Ahmed, Osama Ahmed Amin, A AbdElHakim, K Abosaif, Hossam Kandil, M A G Galal, E E El Hefny, Mazen El Sayed, K Aly, Moustafa Mokarrab, Mohammed Osman, Magdy Abdelhamid, S Mantawy, Mohammad Ridhuan Mohd Ali, S D Kaky, Viviane Khalil, Mahmoud Saraya, Ahmed Talaat, M Nabil, W M Mounir, Karim D. Mahmoud, A Aransa, Ghada Kazamel, S Anwar, Ahmed Al‐Habbaa, M Abd el Monem, A Ismael, M Amin Abu-Sheaishaa, M M Abd Rabou, T M A Hammouda, M Moaaz, Khaled Elkhashab, Tamer Mosaad Ragab, A Rashwan, A Rmdan, Gomaa Abdelrazek, Hassan Ebeid, Haytham Soliman Ghareeb, Nabil Farag, Mohamed Ahmed Zaki, M Seleem, A Torki, Mahmoud Youssef, N A AlLah Nasser, A Rafaat, H Selim, M M Makram, M. A. Khayyal, K Malasi, Ashraf Madkour, M Kolib, H Alkady, H Nagah, M Yossef, A Wafa, E Mahfouz, G Faheem, M Magdy Moris, Ahmed Ragab, Mohammed Ghazal, A Mabrouk, M Hassan, Magdy Mohamed Elmasry, Mohamed Naseem, Sameh Samir, Toomas Marandi, J Reinmets, M Allvee, Aet Saar, Tiia Ainla, A Vaide, M Kisseljova, U Pakosta, Jaan Eha, K Lotamois, Jussi Sia, Juhani Myllymäki, T Pinola, Pasi P. Karjalainen, Tuomas Paana, Jussi Mikkelsson, M Ampio, J Tsivilasvili, P Zurab, Zviad Kereselidze, Rusudan Agladze, A Melia, D Gogoberidze, N Khubua, L Totladze, I Metreveli, A Chikovani, Ingo Eitel, Janine Pöss, M. Werner, A Constantz, C Ahrens, Uwe Zeymer, H Tolksdorf, S Klinger, S. Sack, Tobias Heer, J. Lekakis, John Kanakakis, Iosif Xenogiannis, K Ermidou, Nikolaos Makris,
Abstract Aims The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). Methods and results Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset <24 h in 196 centres across 29 countries. A total of 11 462 patients were enrolled, ...
Oxford University Press
Peter Ludman, Uwe Zeymer, Nicolas Danchin, Petr Kala, Cécile Laroche, Masoumeh Sadeghi, Roberto Caporale, Sameh Mohamed Shaheen, Jacek Legutko, Zaza Iakobishvili, Khalid F. AlHabib, Zuzana Moťovská, Martin Studenčan, Jorge Mimoso, Dávid Becker, Dimitrios Alexopoulos, Zviad Kereseselidze, Siniša Stojković, Parounak Zelveian, A Goda, Erkin М Мirrakhimov, Gani Bajraktari, Hasan Ali Farhan, Pranas Šerpytis, Bent Raungaard, Toomas Marandi, Alice Moore, Martin Quinn, Pasi P. Karjalainen, Gabriel Tatu-Chitoiu, Chris P Gale, Aldo P. Maggioni, Franz Weidinger, A Goda, Naltin Shuka, E Pavli, E Tafaj, Taulant Gishto, Alban Dibra, Arvi Duka, A Gjana, Aleksandra S. Kristo, G Knuti, Aurel Demiraj, E Dado, Endri Hasimi, Leonard Simoni, M Siqeca, Hamayak Sisakian, Hamlet Hayrapetyan, S. A. Markos’yan, L Galustyan, N Arustamyan, H Kzhdryan, Sergey Pepoyan, A Zirkik, Dirk von Lewinski, S Paetzold, I Kienzl, K Mátyás, Thomas Neunteufl, Mariam Nikfardjam, U Neuhold, A Mihalcz, F Glaser, Clemens Steinwender, Christian Reiter, Michael Grund, Dragan Hrnčić, Uta C. Hoppe, Matthias Hammerer, Lynne Hinterbuchner, Christian Hengstenberg, Georg Delle Karth, Iréne Lang, Franz Weidinger, W. Winkler, Matthias Hasun, Johannes Kästner, C. Havel, Michael Derntl, G Oberegger, Johannes Hajos, Christopher Adlbrecht, T. Publig, M-C Leitgeb, R Wilfing, Peter Jirak, Carolyn Y. Ho, L Puskas, Lore Schrutka, Jindřich Špinar, Jiří Pařenica, Ota Hlinomaz, V Fendrychova, Jiří Seménka, J Sikora, Jan Sitar, Ladislav Groch, M Rezek, M Novák, P Kramarikova, Josef Šťásek, J Dušek, Petr Zdráhal, Rostislav Polášek, Jiří Karásek, Jiří Seiner, N Sukova, Ivo Varvařovský, Tomáš Lazarák, Vojtěch Novotný, Jan Matějka, Richard Rokyta, Štefan Volovár, Jan Bělohlávek, Zuzana Moťovská, Michal Širanec, M Kamenik, R Kralik, Bent Raungaard, Jan Ravkilde, Svend Eggert Jensen, Anton Boel Villadsen, K Villefrance, Charlotte Schmidt Skov, Michael Mæng, K Moeller, Hosam Hasan‐Ali, Tarek Ahmed, M Hassan, Ahmed ElGuindy, M Farouk Ismail, A Ibrahim Abd El-Aal, Ahmed Gaafar, Hasnita Hassan, Mohammad Shafie, M Elkhouly, Ahmed Bendary, M Darwish, Yesuf Ahmed, Osama Ahmed Amin, A AbdElHakim, K Abosaif, Hossam Kandil, M A G Galal, E E El Hefny, Mohamed A. Zayed, K Aly, Moustafa Mokarrab, Mohammed Osman, Magdy Abdelhamid, S Mantawy, Mohammad Ridhuan Mohd Ali, S D Kaky, Viviane Khalil, Mahmoud Saraya, Ahmed Talaat, M Nabil, W M Mounir, K Mahmoud A Aransa, Ghada Kazamel, S Anwar, Ahmed Al‐Habbaa, M Abd el Monem, A Ismael, M Amin Abu-Sheaishaa, M M Abd Rabou, T M A Hammouda, M Moaaz, Khaled Elkhashab, Tamer Mosaad Ragab, A Rashwan, A Rmdan, Gomaa Abdelrazek, Hassan Ebeid, Haytham Soliman Ghareeb, Nabil Farag, Mohamed Ahmed Zaki, M Seleem, A Torki, Mahmoud Youssef, N A AlLah Nasser, A Rafaat, H Selim, M M Makram, M. A. Khayyal, K Malasi, Ashraf Madkour, M Kolib, H Alkady, H Nagah, M Yossef, A Wafa, E Mahfouz, G Faheem, M Magdy Moris, Ahmed Ragab, Mohammed Ghazal, A Mabrouk, M Hassan, Magdy Mohamed Elmasry, Mohamed Naseem, Sameh Samir, Toomas Marandi, J Reinmets, M Allvee, Aet Saar, Tiia Ainla, A Vaide, M Kisseljova, U Pakosta, Jaan Eha, K Lotamois, Jussi Sia, Juhani Myllymäki, T Pinola, Pasi P. Karjalainen, Tuomas Paana, Jussi Mikkelsson, M Ampio, J Tsivilasvili, P Zurab, Zviad Kereselidze, Rusudan Agladze, A Melia, D Gogoberidze, N Khubua, L Totladze, I Metreveli, A Chikovani, Ingo Eitel, Janine Pöss, M. Werner, A Constantz, C Ahrens, Uwe Zeymer, H Tolksdorf, S Klinger, S. Sack, Tobias Heer, J. Lekakis, John Kanakakis, Iosif Xenogiannis, K Ermidou, Nikolaos Makris, Argyrios Ntalianis, Fotios K. Katsaros, E Revi, K Kafkala, E Mihelakis, George F. Diakakis, K Grammatikopoulos, D Voutsinos, D. Alexopoulos, Ioanna Xanthopoulou, Virginia Mplani, Stefanos Foussas, Nikolaos A. Papakonstantinou, Nikolaos Patsourakos, A Dimopoulos, A Derventzis, Kyriacos A. Athanasiou, Vasileios Vassilikos, Christodoulos Papadopoulos, Stergios Tzikas, Ioannis Vogiatzis, A Datsios, I Galitsianos, Konstantinos Koutsampasopoulos, Savvas Grigoriadis, A Douras, Nour-Eddine Baka, S Spathis, T Kyrlidis, H. Hatzinikolaou, Róbert Gábor Kiss, Dávid Becker, Fanni Nowotta, Kálmán Tóth, Sofia Szabo, C Lakatos, Zoltán Jambrik, J Ruzsa, Zoltán Ruzsa, Szilárd Róna, Jean C. Toth, A Vargane Kosik, Kálmán Tóth, Gergely Nagy, Z Ondrejkó, Z Körömi, Balázs Botos, M Pourmoghadas, Amir Mohammad Salehi, Gholamreza Massoumi,
To use quality indicators to study the management of ST-segment elevation myocardial infarction (STEMI) in different regions.Prospective cohort study of STEMI within 24 h of symptom onset (11 462 patients, 196 centres, 26 European Society of Cardiology members, and 3 affiliated countries). The median delay between arrival at a percutaneous cardiovascular intervention (PCI) centre and primary PCI was 40 min (interquartile range 20-74) with 65.8% receiving PCI within guideline recommendation of 60 min. ...
Oxford University Press
Uwe Zeymer, Peter Ludman, Nicolas Danchin, Petr Kala, Aldo P. Maggioni, Franz Weidinger, Chris P Gale, B Beleslin, Andrzej Budaj, Ovidiu Chioncel, N Dagres, Nicolas Danchin, Jonathan Emberson, David Erlinge, Michael Glikson, A Gray, Meral Kayıkçıoğlu, Aldo P. Maggioni, V K Nagy, А. О. Недошивин, A-S Petronio, Jolien W. Roos‐Hesselink, L Wallentin, Uwe Zeymer, Franz Weidinger, Uwe Zeymer, Nicolas Danchin, Peter Ludman, Peter Sinnaeve, Petr Kala, Roberto Ferrari, Aldo P. Maggioni, A Goda, Parounak Zelveian, Franz Weidinger, Kiril Karamfilov, Zuzana Moťovská, Uwe Zeymer, Bent Raungaard, Toomas Marandi, Sameh Mohamed Shaheen, Rosa-María Lidón, Pasi P. Karjalainen, Zviad Kereselidze, Dimitrios Alexopoulos, Dávid Becker, Martin Quinn, Zaza Iakobishvili, Hasan Ali Farhan, Masoumeh Sadeghi, Roberto Caporale, Francesco Romeo, Erkin М Мirrakhimov, Pranas Šerpytis, Andrejs Ērglis, Saško Kedev, Matthew Mercieca Balbi, Alice Moore, Dariusz Dudek, Jacek Legutko, Jorge Mimoso, Gabriel Tatu-Chiţoiu, Siniša Stojković, Е. V. Shlyakhto, Khalid F. AlHabib, Matjaž Bunc, Martin Studenčan, Mohamed Sami Mourali, Gani Bajraktari, Marème Konté, Florian Larras, Elin Folkesson Lefrancq, Souad Mekhaldi, Cécile Laroche, Aldo P. Maggioni, A Goda, Naltin Shuka, E Pavli, E Tafaj, Taulant Gishto, Alban Dibra, Arvi Duka, A Gjana, Aleksandra S. Kristo, G Knuti, Aurel Demiraj, E Dado, Endri Hasimi, Leonard Simoni, M Siqeca, Hamayak Sisakian, Hamlet Hayrapetyan, S. A. Markos’yan, L Galustyan, N Arustamyan, H Kzhdryan, Sergey Pepoyan, A Zirkik, Dirk von Lewinski, S Paetzold, I Kienzl, K Mátyás, Thomas Neunteufl, Mariam Nikfardjam, U Neuhold, A Mihalcz, F Glaser, Clemens Steinwender, Christian Reiter, Michael Grund, Dragan Hrnčić, Uta C. Hoppe, Matthias Hammerer, Lynne Hinterbuchner, Christian Hengstenberg, Georg Delle Karth, Iréne Lang, Franz Weidinger, W. Winkler, Matthias Hasun, Johannes Kästner, C. Havel, Michael Derntl, G Oberegger, Johannes Hajos, Christopher Adlbrecht, T. Publig, M-C Leitgeb, R Wilfing, Peter Jirak, Carolyn Y. Ho, L Puskas, Lore Schrutka, Jindřich Špinar, Jiří Pařenica, Ota Hlinomaz, V Fendrychova, Jiří Seménka, J Sikora, Jan Sitar, Ladislav Groch, M Rezek, M Novák, P Kramarikova, Josef Šťásek, J Dušek, Petr Zdráhal, Rostislav Polášek, Jiří Karásek, Jiří Seiner, N Sukova, Ivo Varvařovský, Tomáš Lazarák, Vojtěch Novotný, Jan Matějka, Richard Rokyta, Štefan Volovár, Jan Bělohlávek, Zuzana Moťovská, Michal Širanec, M Kamenik, R Kralik, Bent Raungaard, Jan Ravkilde, Svend Eggert Jensen, Anton Boel Villadsen, K Villefrance, Charlotte Schmidt Skov, Michael Mæng, K Moeller, Hosam Hasan‐Ali, Tarek Ahmed, M Hassan, Ahmed ElGuindy, M Farouk Ismail, A Ibrahim Abd El-Aal, Ahmed Gaafar, Hasnita Hassan, Mohammad Shafie, M Elkhouly, Ahmed Bendary, M Darwish, Yesuf Ahmed, Oreekha Amin, A AbdElHakim, K Abosaif, Hossam Kandil, M A G Galal, E E El Hefny, Mazen El Sayed, K Aly, Moustafa Mokarrab, Mohammed Osman, Magdy Abdelhamid, S Mantawy, Mohammad Ridhuan Mohd Ali, S D Kaky, Viviane Khalil, Mahmoud Saraya, Ahmed Talaat, M Nabil, W M Mounir, Karim D. Mahmoud, A Aransa, Ghada Kazamel, S Anwar, Ahmed Al‐Habbaa, M Abd el Monem, A Ismael, M Amin Abu-Sheaishaa, M M Abd Rabou, T M A Hammouda, M Moaaz, Khaled Elkhashab, Tamer Mosaad Ragab, A Rashwan, A Rmdan, Gomaa Abdelrazek, Hassan Ebeid, Haytham Soliman Ghareeb, Nabil Farag, Mohamed Ahmed Zaki, M Seleem, A Torki, Mahmoud Youssef, N A AlLah Nasser, A Rafaat, H Selim, M M Makram, M. A. Khayyal, K Malasi, Ashraf Madkour, M Kolib, H Alkady, H Nagah, M Yossef, A Wafa, E Mahfouz, G Faheem, M Magdy Moris, Ahmed Ragab, Mohammed Ghazal, A Mabrouk, M Hassan, Magdy Mohamed Elmasry, Mohamed Naseem, Sameh Samir, Toomas Marandi, J Reinmets, M Allvee, Aet Saar, Tiia Ainla, A Vaide, M Kisseljova, U Pakosta, Jaan Eha, K Lotamois, Jussi Sia, Juhani Myllymäki, T Pinola, Pasi P. Karjalainen, Tuomas Paana, Jussi Mikkelsson, M Ampio, J Tsivilasvili, P Zurab, Zviad Kereselidze, Rusudan Agladze, A Melia, D Gogoberidze, N Khubua, L Totladze, I Metreveli, A Chikovani, Ingo Eitel, Janine Pöss, M. Werner, A Constantz, C Ahrens, Uwe Zeymer, H Tolksdorf, S Klinger, S. Sack, Tobias Heer, J. Lekakis, John Kanakakis, Iosif Xenogiannis, K Ermidou, Nikolaos Makris, Argyrios Ntalianis, Fotios K. Katsaros, E Revi, K Kafkala, E Mihelakis, George F. Diakakis, K Grammatikopoulos,
The Acute Cardiac Care Association (ACCA)-European Association of Percutaneous Coronary Intervention (EAPCI) Registry on ST-elevation myocardial infarction (STEMI) of the EurObservational programme (EORP) of the European Society of Cardiology (ESC) registry aimed to determine the current state of the use of reperfusion therapy in ESC member and ESC affiliated countries and the adherence to ESC STEMI guidelines in patients with STEMI.Between 1 January 2015 and 31 March 2018, a total of 11 462 patients ...
Oxford University Press
Zdeněk Farka, Tomáš Juřík, Matěj Pastucha, David Kovář, Karel Lacina, Petr Skládal,
Abstract A label‐free immunosensor for rapid detection of Salmonella Typhimurium based on electrochemical impedance spectroscopy was developed. Specific antibody was immobilized to a screen‐printed electrode via cysteamine monolayer activated with glutaraldehyde and the impedance was measured between two gold electrodes. Different procedures for sample treatment (combinations of heat and sonication) were tested and their impact on the assay performance was compared. Atomic force microscopy was used ...
Tópico(s): Salmonella and Campylobacter epidemiology
2016 - Wiley | Electroanalysis
Barbora Korpallová, Matej Samoš, Tomáš Bolek, Ingrid Škorňová, František Kovář, Peter Kubisz, Ján Staško, Marián Mokáň,
The monitoring of coagulation by viscoelastometric methods—thromboelastography and rotational thromboelastometry—may detect the contributions of cellular and plasma components of hemostasis. These methods might overcome some of the serious limitations of conventional laboratory tests. Viscoelastic testing can be repeatedly performed during and after surgery and thus provides a dynamic picture of the coagulation process during these periods. Several experiences with the use of these methods in cardiovascular ...
Tópico(s): Blood properties and coagulation
2018 - SAGE Publishing | Clinical and Applied Thrombosis/Hemostasis
Matej Samoš, Radoslava Šimonová, František Kovář, Lukáš Duraj, Jana Fedorová, Péter Galajda, Ján Staško, Marián Fedor, Peter Kubisz, Marián Mokáň,
Stent thrombosis is a morbid complication after percutaneous coronary intervention. Dual antiplatelet therapy significantly reduces stent thrombosis risk and forms currently the basis in acute ST elevation myocardial infarction pharmacologic treatment. The introduction of clopidogrel has made a major advance in the acute coronary syndrome treatment. However, there is growing evidence about failure in antiplatelet response after clopidogrel, which may lead to subsequent risk of future thrombotic ...
Tópico(s): Acute Myocardial Infarction Research
2014 - Elsevier BV | The American Journal of Emergency Medicine
Matej Samoš, Marián Fedor, František Kovář, Lukáš Duraj, Lucia Stančiaková, Péter Galajda, Ján Staško, Peter Kubisz, Marián Mokáň,
Stent thrombosis is a morbid complication following percutaneous coronary intervention (PCI). Dual antiplatelet therapy significantly reduces stent thrombosis risk. However, the antiplatelet response to clopidogrel – the most frequently used ADP receptor antagonist in post-PCI patients – varies among individuals. High on-treatment platelet reactivity was repeatedly associated with the risk of stent thrombosis. Ticagrelor is a novel ADP receptor blocker that has shown greater, more rapid and more consistent ...
Tópico(s): Lipoproteins and Cardiovascular Health
2015 - Lippincott Williams & Wilkins | Blood Coagulation & Fibrinolysis
Matej Samoš, Lucia Stančiaková, Jela Ivanková, Ján Staško, František Kovář, Miroslava Dobrotová, Péter Galajda, Peter Kubisz, Marián Mokáň,
Tópico(s): Heparin-Induced Thrombocytopenia and Thrombosis
2014 - Springer Science+Business Media | Journal of Thrombosis and Thrombolysis
Tomáš Bolek, Matej Samoš, Ingrid Škorňová, František Kovář, Péter Galajda, Ján Staško, Peter Kubisz, Marián Mokáň,
Proton pump inhibition (PPI) administered together with antiplatelet and anticoagulant agents reduces the risk of gastrointestinal hemorrhage. Several novel antithrombotic agents have been recently introduced for patients with acute coronary syndrome (prasugrel and ticagrelor) or for patients requiring long-term anticoagulation (dabigatran, rivaroxaban, apixaban, edoxaban, and betrixaban). In fact, these agents might offer even stronger inhibition of platelets or coagulation compared with older agents; ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2018 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology
Petr Kovář, Michal Kravčenko, Matěj Krbeček, Adam Silber,
Let G be a simple graph, let f : V (G) → {1, 2, . . ., |V (G)|} be a bijective mapping.The weight of v ∈ V (G) is the sum of labels of all vertices adjacent to v. We say that f is a distance magic labeling of G if the weight of every vertex is the same constant k and we say that f is a handicap magic labeling of G if the weight of every vertex v is + f (v) for some constant .Graphs that allow such labelings are called distance magic or handicap, respectively.Distance magic and handicap labelings of regular graphs are ...
Tópico(s): Advanced Graph Theory Research
2017 - VSB – Technical University of Ostrava | Advances in Electrical and Electronic Engineering
Matej Samoš, Marián Fedor, František Kovář, Michal Mokáň, Tomáš Bolek, Péter Galajda, Peter Kubisz, Marián Mokáň,
Type 2 diabetes (T2D) is associated with several abnormalities in haemostasis predisposing to thrombosis. Moreover, T2D was recently connected with a failure in antiplatelet response to clopidogrel, the most commonly used ADP receptor blocker in clinical practice. Clopidogrel high on-treatment platelet reactivity (HTPR) was repeatedly associated with the risk of ischemic adverse events. Patients with T2D show significantly higher residual platelet reactivity on ADP receptor blocker therapy and are ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2015 - Hindawi Publishing Corporation | Journal of Diabetes Research
Matej Samoš, Tomáš Bolek, Jela Ivanková, Lucia Stančiaková, František Kovář, Péter Galajda, Peter Kubisz, Ján Staško, Marián Mokáň,
Heparin-induced thrombocytopenia (HIT) is a life or limb-threatening thrombotic thrombocytopenia. HIT is traditionally treated with factor-IIa inhibitors such as bivalirudin, lepirudin, or argatroban. However, these agents usually require parenteral administration and are not generally available in all countries. Recently, several experiences with novel oral anticoagulants (NOACs) administration to treat HIT had been reported. NOACs generally offer advantages such as consistent and predictable anticoagulation, ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2016 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology
Peter Bánovčin, Ingrid Škorňová, Matej Samoš, Martin Schnierer, Tomáš Bolek, František Kovář, Ján Staško, Peter Kubisz, Marián Mokáň,
Activated factor X (factor Xa) plays an important role in regulation of platelets. The aim of this study was to test the effect of direct oral factor Xa inhibitors-rivaroxaban and apixaban-on platelet aggregation in patients with nonvalvular atrial fibrillation.This single-center pilot study enrolled 21 factor Xa inhibitors-treated (9 rivaroxaban-treated and 12 apixaban-treated) patients with nonvalvular atrial fibrillation. The trough and peak samples of these patients were tested for adenosine diphosphate ( ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2017 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology
João Pedro Marto, Davide Strambo, George Ntaios, Thanh N. Nguyen, Roman Herzig, Anna Członkowska, Jelle Demeestere, Malek Mansour, Alexander Salerno, Susanne Wegener, Philipp Baumgartner, Carlo W. Cereda, Giovanni Bianco, Morin Beyeler, Marcel Arnold, Emmanuel Carrera, Paolo Machi, Valerian Altersberger, Leo H. Bonati, Henrik Gensicke, Manuel Bolognese, Nils Peters, Stephan G. Wetzel, Marta Magriço, João Nuno Ramos, João Sargento‐Freitas, Rita Sà Machado, Carolina Maia, Egídio Machado, Ana Paiva Nunes, Patrícia Ferreira, Teresa Pinho e Melo, Mariana Carvalho Dias, André Paula, Manuel Alberto Correia, Pedro Castro, Elsa Azevedo, Luís Albuquerque, José Matías Alves, Joana Ferreira-Pinto, Torcato Meira, Liliana Pereira, Miguel Rodrigues, André Araújo, Marta Rodrigues, Mariana Rocha, Ângelo Fonseca, Luís Ribeiro, Ricardo Varela, Sofia Malheiro, Manuel Cappellari, Cecilia Zivelonghi, Giulia Sajeva, Andrea Zini, Mauro Gentile, Stefano Forlivesi, Ludovica Migliaccio, Maria Sessa, Sara La Gioia, Alessandro Pezzini, Davide Sangalli, Marialuisa Zedde, Rosario Pascarella, Carlo Ferrarese, Simone Beretta, Susanna Diamanti, Ghil Schwarz, Giovanni Frisullo, Simona Marcheselli, Pierre Seners, Candice Sabben, Simon Escalard, Michel Piotin, Benjamin Maïer, Guillaume Charbonnier, Fabrice Vuillier, Loïc Legris, Pauline Cuisenier, Francesca R. Vodret, Gaultier Marnat, Jean-Sébastien Liegey, Igor Sibon, Fabian Flottmann, Gabriel Broocks, Nils-Ole Gloyer, Ferdinand O. Bohmann, Jan Hendrik Schaefer, Christian H. Nolte, Heinrich J. Audebert, Eberhard Siebert, M. Sýkora, Wilfried Lang, Julia Ferrari, Lukas Mayer‐Suess, Michael Knoflach, Elke R. Gizewski, Jeffrey Stolp, Lotte J. Stolze, Jonathan M. Coutinho, Paul J. Nederkoorn, Ido R. van den Wijngaard, Joke De Meris, Robin Lemmens, Sylvie De Raedt, Fenne Vandervorst, Matthieu Pierre Rutgers, Antoine Guilmot, Anne Dusart, Flavio Bellante, Patricia Calleja‐Castaño, Fernando Ostos, Guillermo González‐Ortega, Paloma Martín‐Jiménez, Sebastián García‐Madrona, Antonio Culebras, Rocío Vera, María Consuelo Matute, Blanca Fuentes, María Alonso de Leciñana, Ricardo Rigual, Exuperio Díez–Tejedor, Soledad Pérez-Sánchez, Joan Montaner, Fernando Díaz‐Otero, Natalia Pérez-de-la-Ossa, Belén Flores-Pina, Lucía Muñoz-Narbona, Ángel Chamorro, Alejandro Rodríguez-Vázquez, Arturo Renú, Óscar Ayo‐Martín, Francisco Hernández‐Fernández, Tomás Segura, H. Tejada Meza, Daniel Sagarra-Mur, M Serrano-Ponz, Thant Hlaing, Isaiah See, Robert Simister, David J. Werring, Espen Saxhaug Kristoffersen, Annika Nordanstig, Katarina Jood, Alexandros Rentzos, Libor Šimůnek, Dagmar Krajíčková, Antonı́n Krajina, Robert Mikulík, Martina Cviková, Jan Vinklárek, David Školoudík, Martin Roubec, Eva Hurtíková, Rostislav Hrubý, Svatopluk Ostrý, Ondřej Škoda, Marek Pernicka, Lubomír Jurák, Zuzana Eichlová, Martin Jíra, Martin Kovář, Michal Panský, Pavel Mencl, Hana Paloušková, Aleš Tomek, Petr Janský, Anna Olšerová, Martin Šrámek, Roman Havlíček, Petr Malý, Lukáš Trakal, Jan Fiksa, Matěj Slovák, Michał Karliński, Maciej Nowak, Halina Sienkiewicz‐Jarosz, Anna Bochyńska, Paweł Wrona, Tomasz Homa, Katarzyna Sawczyńska, Agnieszka Słowik, Ewa Włodarczyk, Marcin Wiącek, Izabella Tomaszewska-Lampart, Bartosz Sieczkowski, Halina Bartosik-Psujek, Marta Bilik, Anna Bandzarewicz, Małgorzata Dorobek, Justyna Zielińska-Turek, Marta Nowakowska‐Kotas, Krystian Obara, Paweł Urbanowski, Sławomir Budrewićz, Maciej Guziński, Milena Świtońska, Iwona A. Rutkowska, Paulina Sobieszak-Skura, Beata Łabuz-Roszak, Aleksander Dȩbiec, Jacek Staszewski, Adam Stȩpień, Jacek Zwiernik, Grzegorz Wasilewski, Cristina Tiu, Elena Terecoasă, Răzvan Alexandru Radu, Anca Negrilă, Bogdan Dorobăț, Cristina Panea, Vlad Eugen Tiu, Simona Petrescu, Atilla Ozdemir, Mostafa Mahmoud, Hussam El-Samahy, Hazem Abdelkhalek, Jasem Al–Hashel, Ismail Ibrahim Ismail, Athari Salmeen, Abdoreza Ghoreishi, Sergiu Sabetay, Hana Gross, Piers Klein, Mohamad Abdalkader, Pascal Jabbour, Kareem El Naamani, Stavropoula Tjoumakaris, Rawad Abbas, Ghada Mohamed, Alex Chebl, Jiangyong Min, Majesta Hovingh, Jenney P. Tsai, Muhib Khan, Krishna Nalleballe, Sanjeeva Onteddu, Hesham Masoud, Mina Michael, Navreet Kaur, Laith Maali, Michael Abraham, Priyank Khandelwal, Ivo Bach, Melody Ong, Denis Babici, Ayaz Khawaja, Maryam Hakemi, Kumar Rajamani, Vanessa Cano-Nigenda, Antonio Araúz, Pablo Amaya, Natalia Llanos, Akemi Arango, Miguel A. Vences, Jose Dominguo Barrientos Guerra, Rayllene Caetano, Rodrigo Targa Martins, Sergio Scollo, Patrick Yalung, Shashank Nagendra, Abhijit Gaikwad, Kwon‐Duk Seo, Georgios Georgiopoulos, Raul G. Nogueira, Patrik Michel,
Background and Objectives COVID-19–related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19. Methods This was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between ...
Tópico(s): COVID-19 and healthcare impacts
2022 - Lippincott Williams & Wilkins | Neurology
Stanislava Darulová, Matej Samoš, Juraj Sokol, Radoslava Šimonová, František Kovář, Péter Galajda, Ján Staško, Peter Kubisz, Marián Mokáň,
Female, 51.Sticky platelets syndrome.Pulmonary embolism.-Thrombolysis.Hematology.Disease of unknown ethiology.Sticky platelets syndrome (SPS) is an inherited thrombophilia characterized by platelet hyperaggregability, which can lead to the higher risk of thrombosis. The etiology of SPS remains unclear, but several gene polymorphisms have been recently studied and autosomal dominant heredity is suspected. Although SPS is traditionally connected with arterial thrombosis, several cases of SPS as a cause ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2013 - International Scientific Information Inc. | American Journal of Case Reports
Tomáš Bolek, Matej Samoš, Radoslava Šimonová, František Kovář, Marián Fedor, Péter Galajda, Ján Staško, Peter Kubisz, Marián Mokáň,
Proton pump inhibition (PPI) administrated together with adenosine diphosphate (ADP) receptor blockers (ADPRB) significantly reduces the risk of gastrointestinal bleeding. Nevertheless, there is a heated discussion about an interaction between PPI and ADPRB that leads to high on-treatment platelet reactivity (HTPR).Is there a relationship between pantoprazole PPI and HTPR on ADPRB therapy in patients with acute ST-elevation myocardial infarction (STEMI).Single center pilot study in patients with acute ...
Tópico(s): Acute Myocardial Infarction Research
2016 - Lippincott Williams & Wilkins | American Journal of Therapeutics
Vojtěch Kovář, Matěj Šilinger, Oldřich Fatka, Rainer Brocke,
... of the Czech Republic.Notes on contributorsVojtěch KovářVOJTĚCH KOVÁŘ is a PhD student at the Institute of Geology and Palaeontology, Faculty of Science, Charles University, Czech Republic. His research is focused on the Lower Paleozoic palynology, mainly acritarchs and small carbonaceous fossils.Matěj ŠilingerMATĚJ ŠILINGER is a PhD student at the ...
Tópico(s): Isotope Analysis in Ecology
2023 - Taylor & Francis | Palynology
Tópico(s): Graph Labeling and Dimension Problems
2024 - Indonesian Combinatorial Society (InaCombS); Graph Theory and Applications (GTA) Research Centre; University of Newcastle, Austr | Electronic Journal of Graph Theory and Applications
Matej Samoš, Tomáš Bolek, Lucia Stančiaková, Ingrid Škorňová, Jela Ivanková, František Kovář, Péter Galajda, Peter Kubisz, Ján Staško, Marián Mokáň,
Type 2 diabetes (T2D) is connected with several abnormalities in haemostasis; and with higher risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NV-AF). However, it is recently unknown whether T2D affects the activity of direct oral anticoagulants (DOACs). The aim of this study was to determine the impact of T2D on DOACs activity in patients with NV-AF.This pilot prospective study enrolled totally 65 patients with NV-AF (20 dabigatran-treated, 110 mg/twice daily; ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2017 - Elsevier BV | Diabetes Research and Clinical Practice
Matej Samoš, Tomáš Bolek, Lucia Stančiaková, Ingrid Škorňová, Peter Bánovčin, František Kovář, Ján Staško, Péter Galajda, Peter Kubisz, Marián Mokáň,
: The number of patients with nonvalvular atrial fibrillation (NV-AF) who require long-term anticoagulation and also have a higher risk of bleeding is increasing. Recently, there is no information regarding real on-treatment anti-Xa activity in patients with NV-AF and a higher risk of bleeding who receive oral factor Xa inhibitors. The aim of this study was to determine trough and peak anti-Xa activity in these patients. This single-centre pilot study enrolled 41 patients with NV-AF and a higher risk ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2018 - Lippincott Williams & Wilkins | Blood Coagulation & Fibrinolysis
Matej Samoš, Lucia Stančiaková, Lukáš Duraj, František Kovář, Marián Fedor, Radoslava Šimonová, Tomáš Bolek, Péter Galajda, Ján Staško, Peter Kubisz, Marián Mokáň,
Rotation thromboelastometry (ROTEM) is a viscoelastometric point-of-care-test for the complex evaluation of changes in hemostasis, performed in whole blood. However, no prospective study evaluating the efficacy of the antiplatelet therapy using ROTEM was performed.Fifty-six patients (34 men, 22 women, mean age 67.75 years, and age range 34-88 years) with acute ST-elevation myocardial infarction (STEMI), treated with dual antiplatelet therapy, undergoing urgent coronary angiography and percutaneous ...
Tópico(s): Acute Myocardial Infarction Research
2017 - Wolters Kluwer | Medicine
Marián Fedor, Radoslava Šimonová, Jana Fedorová, Ingrid Škorňová, Lukáš Duraj, Matej Samoš, Ján Staško, František Kovář, Marián Mokáň, Peter Kubisz,
Abstract Dual antiplatelet treatment with clopidogrel and aspirin represents standard regimen in prevention of thromboembolic events in patients with ischemic heart disease undergoing percutaneous coronary intervention (PCI). One of the greatest pitfalls of clopidogrel treatment is large inter-individual variability in response. Large amount of patients does not respond adequately and therefore are not „protected“ even in spite of receiving the therapy. Poor responders are exposed to three-fold increased ...
Tópico(s): Coronary Interventions and Diagnostics
2013 - De Gruyter Open | Acta Medica Martiniana
Marián Fedor, Matej Samoš, Radoslava Šimonová, Jana Fedorová, Ingrid Škorňová, Lukáš Duraj, Ján Staško, František Kovář, Marián Mokáň, Peter Kubisz,
Introduction: Dual antiplatelet treatment (DAPT) with clopidogrel and aspirin represents common approach in prevention of thromboembolic events in patients with acute coronary syndrome undergoing percutaneous coronary intervention (PCI). The drawback of clopidogrel treatment is large interindividual variability in response. Aim: Our article aims to suggesting the most convenient method in monitoring the DAPT of post-PCI patients. Methods: We analyzed the on-treatment platelet reactivity by light transmission ...
Tópico(s): Acute Myocardial Infarction Research
2014 - SAGE Publishing | Clinical and Applied Thrombosis/Hemostasis
Davide Strambo, João Pedro Marto, George Ntaios, Thanh N. Nguyen, Patrik Michel, Roman Herzig, Anna Członkowksa, Jelle Demeestere, Malek Mansour, Georgios Georgiopoulos, Raul G. Nogueira, Alexander Salerno, Susanne Wegener, Philipp Baumgartner, Carlo W. Cereda, Giovanni Bianco, Morin Beyeler, Marcel Arnold, Emmanuel Carrera, Paolo Machi, Valerian Altersberger, Leo H. Bonati, Henrik Gensicke, Manuel Bolognese, Nils Peters, Stephan G. Wetzel, Marta Magriço, João Nuno Ramos, João Sargento‐Freitas, Rita Sà Machado, Carolina Maia, Egídio Machado, Ana Paiva-Nunes, Patrícia Ferreira, Teresa Pinho‐e‐Melo, Mariana Carvalho-Dias, André Paula, Manuel Alberto Correia, Pedro Castro, Elsa Azevedo, Luís Albuquerque, José Nuno-Alves, Joana Ferreira-Pinto, Torcato Meira, Liliana Pereira, Miguel Rodrigues, André Araújo, Marta Rodrigues, Mariana Rocha, Ângelo Fonseca, Luís Ribeiro, Ricardo Varela, Manuel Cappellari, Cecilia Zivelonghi, Giulia Sajeva, Andrea Zini, Mauro Gentile, Stefano Forlivesi, Ludovica Migliaccio, Maria Sessa, Alessandro Pezzini, Davide Sangalli, Marialuisa Zedde, Rosario Pascarella, Susanna Diamanti, Simone Beretta, Ghil Schwarz, Giovanni Frisullo, Simona Marcheselli, Pierre Seners, Candice Sabben, Simon Escalard, Michel Piotin, Benjamin Maïer, Guillaume Charbonnier, Fabrice Vuillier, Loïc Legris, Pauline Cuisenier, Francesca R. Vodret, Gaultier Marnat, Jean-Sébastien Liegey, Igor Sibon, Fabian Flottmann, Gabriel Broocks, Nils-Ole Gloyer, Ferdinand O. Bohmann, Jan Hendrik Schaefer, Christian H. Nolte, Heinrich J. Audebert, Eberhard Siebert, M. Sýkora, Wilfried Lang, Julia Ferrari, Lukas Mayer‐Suess, Michael Knoflach, Elke R. Gizewski, Jeffrey Stolp, Lotte J. Stolze, Jonathan M. Coutinho, Paul J. Nederkoorn, Ido van-den-Wijngaard, Joke de Meris, Robin Lemmens, Sylvie De Raedt, Fenne Vandervorst, Matthieu Pierre Rutgers, Antoine Guilmot, Anne Dusart, Flavio Bellante, Patricia Calleja‐Castaño, Fernando Ostos, Guillermo González‐Ortega, Paloma Martín‐Jiménez, Sebastián García‐Madrona, Antonio Culebras, Rocío Vera, María-Consuelo Matute, Blanca Fuentes, María Alonso de Leciñana, Ricardo Rigual, Exuperio Díez–Tejedor, Soledad Pérez-Sánchez, Joan Montaner, Fernando Díaz‐Otero, Natàlia Pérez de la Ossa, Belén Flores-Pina, Lucía Muñoz-Narbona, Ángel Chamorro, Alejandro Rodríguez-Vázquez, Arturo Renú, Óscar Ayo‐Martín, Francisco Hernández‐Fernández, Tomás Segura, H. Tejada Meza, Thant Hlaing, Isaiah See, Robert Simister, David J. Werring, Espen Saxhaug Kristoffersen, Annika Nordanstig, Katarina Jood, Alexandros Rentzos, Libor Šimůnek, Dagmar Krajíčková, Antonı́n Krajina, Robert Mikulík, Martina Cviková, Jan Vinklárek, David Školoudík, Martin Roubec, Eva Hurtíková, Rostislav Hrubý, Svatopluk Ostrý, Ondřej Škoda, Marek Pernicka, Lubomír Kočí, Zuzana Eichlová, Martin Jíra, Martin Kovář, Michal Panský, Pavel Mencl, Hana Paloušková, Aleš Tomek, Petr Janský, Anna Olšerová, Martin Šrámek, Roman Havlíček, Petr Malý, Lukáš Trakal, Jan Fiksa, Matěj Slovák, Michał Karliński, Maciej Nowak, Halina Sienkiewicz‐Jarosz, Anna Bochyńska, Paweł Wrona, Tomasz Homa, Katarzyna Sawczyńska, Agnieszka Słowik, Ewa Włodarczyk, Marcin Wiącek, Izabella Tomaszewska-Lampart, Bartosz Sieczkowski, Halina Bartosik-Psujek, Marta Bilik, Anna Bandzarewicz, Małgorzata Dorobek, Justyna Zielińska-Turek, Marta Nowakowska‐Kotas, Krystian Obara, Paweł Urbanowski, Sławomir Budrewićz, Maciej Guziński, Milena Świtońska, Iwona A. Rutkowska, Paulina Sobieszak-Skura, Beata Łabuz-Roszak, Aleksander Dȩbiec, Jacek Staszewski, Adam Stȩpień, Jacek Zwiernik, Grzegorz Wasilewski, Cristina Tiu, Elena-Oana Terecoasă, Razvan-Alexandru Radu, Anca Negrilă, Bogdan Dorobăț, Cristina Panea, Vlad Eugen Tiu, Simona Petrescu, Atilla Özcan-Özdemir, Mostafa Mahmoud, Hussam El-Samahy, Hazem Abdelkhalek, Jasem Al–Hashel, Ismail Ibrahim Ismail, Athari Salmeen, Abdoreza Ghoreishi, Sergiu Sabetay, Hana Gross, Piers Klein, Mohamad Abdalkader, Pascal Jabbour, Kareem El Naamani, Stavropoula Tjoumakaris, Rawad Abbas, Ghada-A. Mohamed, Alex Chebl, Jiangyong Min, Majesta Hovingh, Jenny P. Tsai, Muhib-A. Khan, Krishna Nalleballe, Sanjeeva Onteddu, Hesham Masoud, Mina Michael, Navreet Kaur, Laith Maali, Michael Abraham, Priyank Khandelwal, Ivo Bach, Melody Ong, Denis Babici, Ayaz-M. Khawaja, Maryam Hakemi, Kumar Rajamani, Vanessa Cano-Nigenda, Antonio Araúz, Pablo Amaya, Natalia Llanos, Akemi Arango, Miguel A. Vences, José-Domingo Barrientos, Rayllene Caetano, Rodrigo Targa, Sergio Scollo, Patrick Yalung, Shashank Nagendra, Abhijit Gaikwad, Kwon‐Duk Seo,
The association of COVID-19 with higher bleeding risk and worse outcomes in acute ischemic stroke (AIS) undergoing revascularization may be related to the presence of infection symptoms. We aimed to assess the safety and outcomes of revascularization treatments in patients with AIS with asymptomatic COVID-19 (AS-COVID) or symptomatic COVID-19 (S-COVID).
Tópico(s): COVID-19 and healthcare impacts
2023 - Lippincott Williams & Wilkins | Stroke
Matej Samoš, Lucia Stančiaková, Ingrid Škorňová, Tomáš Bolek, František Kovář, Ján Staško, Péter Galajda, Marián Mokáň, Peter Kubisz,
Direct oral anticoagulants (DOACs) offer consistent and predictable anticoagulation, oral administration with good patient compliance and a good safety profile. Dabigatran - a direct thrombin inhibitor, apixaban and rivaroxaban - direct factor Xa inhibitors are now largely used for anticoagulation in patients with nonvalvular atrial fibrillation and in patients with venous thromboembolism. These agents have emerged as an expediential clinical choice in long-term anticoagulation for an increasing number ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2017 - Bentham Science Publishers | Current Drug Metabolism
Farka Zdenek, Jurik Tomas, Pastucha Matej, Kovar David, Lacina Karel, Skladal Petr,
Tópico(s): Healthcare and Venom Research
2016 - Wiley | Electroanalysis
Martin Kovar, Lucas Almeida Cypriano, Matej Kučera, Pavel Ptáček,
Abstract Due to lack of advanced navigation systems, secondary airports are normally unable to support instrument approaches in low visibility conditions (LVC) more adverse than Category (CAT) I, making them inaccessible during such conditions. Incoming flights are then delayed, diverted to adjacent airports, or cancelled before take-off. This paper presents an onboard navigation solution, under development in scope of SESAR 2020 Solution PJ02-W2- 17.2, which focuses on technology development to mitigate ...
Tópico(s): Aviation Industry Analysis and Trends
2023 - IOP Publishing | Journal of Physics Conference Series
Matej Samoš, Marián Fedor, František Kovář, Lukáš Duraj, Jana Fedorová, Péter Galajda, Ján Staško, Tomáš Bolek, Peter Kubisz, Marián Mokáň,
Aktivácia a následná agregácia trombocytov hrá kľúčovú úlohu pri vzniku arteriálnej trombózy, a je teda hlavným terapeutickým cieľom v liečbe akútnych koronárnych syndrómov. Duálna antiagregačná liečba kyselinou acetylsalicylovou a antagonistom receptorov P2Y12 pre ADP tvorí v súčasnosti základ farmakologickej liečby akútneho infarktu myokardu s eleváciami segmentu ST (STEMI). Existuje však široká variabilita vo farmakodynamickej odpovedi na klopidogrel, ktorý je najpoužívanejším antagonistom receptorov ...
Tópico(s): Diabetes Treatment and Management
2014 - Česká kardiologická společnost | Cor et Vasa
Matej Samoš, Marián Fedor, František Kovář, Péter Galajda, Tomáš Bolek, Lucia Stančiaková, Jana Fedorová, Ján Staško, Peter Kubisz, Marián Mokáň,
Background . The aim of this study was to validate the impact of type 2 diabetes (T2D) on the platelet reactivity in patients with acute ST elevation myocardial infarction (STEMI) treated with adenosine diphosphate (ADP) receptor blockers. Methods . A pilot prospective study was performed. Totally 67 patients were enrolled. 21 patients had T2D. Among all study population, 33 patients received clopidogrel and 34 patients received prasugrel. The efficacy of ADP receptor blocker therapy had been tested in ...
Tópico(s): Coronary Interventions and Diagnostics
2016 - Hindawi Publishing Corporation | Journal of Diabetes Research
Peter Kubisz, Lukáš Duraj, Marián Fedor, Matej Samoš, František Kovář, Jana Fedorová, Ján Staško,
Tópico(s): Neurological and metabolic disorders
2014 - Elsevier BV | Thrombosis Research