
Maurício Gonçalves da Costa Sousa, Gabriela Conceição de Almeida, Danilo César Martins Mota, Rosiane Andrade da Costa, Simoni Campos Dias, Samuel Nunes Limberger, Frank Ko, Li Ting Lin, Evan F. Haney, Hashem Etayash, Beverlie Baquir, Michael J. Trimble, Ya Shen, Zheng Su, Markus Haapasalo, Daniel Pletzer, Letícia Chaves de Souza, Gláucia Schuindt Teixeira, Renato Silva, Robert E. W. Hancock, Octávio Luiz Franco, Taia Maria Berto Rezende,
Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools for dentistry. Here, different scaffolds were tested for use during the pulp revascularization process, including poly(vinyl alcohol)-PVA hydrogels or resins, collagen hydrogels and poly(vinyl alcohol) PVA/Chitosan (PVA/CS) nanofibers. Based on time to degradation (21 days), nanofibers were chosen to be incorporated with ciprofloxacin and IDR-1002 (each at 50 mg/g). Nanofibers ...
Tópico(s): Oral microbiology and periodontitis research
2022 - Elsevier BV | Bioactive Materials

Letícia Ferreira Lima, Maurício Gonçalves da Costa Sousa, Gisele Regina Rodrigues, Kamila Botelho Sampaio de Oliveira, Ana Margarida Pereira, André da Costa, Raúl Machado, Octávio Luiz Franco, Simoni Campos Dias,
Elastin-like polypeptides (ELPs) are biopolymers formed by amino acid sequences derived from tropoelastin. These biomolecules can be soluble below critical temperatures, forming aggregates at higher temperatures, which makes them an interesting source for the design of different nanobiomaterials. These nanobiomaterials can be obtained from heterologous expression in several organisms such as bacteria, fungi, and plants. Thanks to the many advantages of ELPs, they have been used in the biomedical ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2022 - Frontiers Media | Frontiers in Nanotechnology

Hélder Lopes, Paula Cristina Almeida Remoaldo, Maurício Gonçalves e Silva, Vítor Ribeiro, Javier Martín Vide,
One of the major challenges’ tourism faces today is climate change, which inevitably involves adjusting many destinations and tourists to new scenarios. For that, a literature review about the link between tourism and climate is mandatory. Therefore, the present paper aims to establish the evolution of the relationship between tourism and climate, since relevant studies were published from 1940 to 2020. A bibliometric analysis using qualitative and quantitative methods were used for measuring the ...
Tópico(s): Sport and Mega-Event Impacts
2021 - Asociación Española de Geografía | Boletín de la Asociación de Geógrafos Españoles

Maurício Gonçalves C. Sousa, Taia Maria Berto Rezende, Octávio Luiz Franco,
Microbial infections are a major worldwide public health problem because a number of microorganisms can show drug resistance. Antimicrobial peptides (AMPs) are small biomolecules that present antimicrobial and immunomodulatory activities. Despite their great potential, there are still many barriers to the formulation of these molecules. In this context, nanotechnological approaches such as nanofibers are candidate drug-delivery systems for AMP formulations. These nanomaterials have a large contact ...
Tópico(s): Graphene and Nanomaterials Applications
2021 - Elsevier BV | Drug Discovery Today

Maurício Gonçalves C. Sousa, Patrícia Diniz Xavier, Ana Paula de Castro Cantuária, Rayssa Aragão Porcino, Jeeser Alves de Almeida, Octávio Luiz Franco, Taia Maria Berto Rezende,
Regenerative therapies such as dental pulpal revascularization appear as an option for traumatized immature permanent teeth. However, the triple antibiotic paste - TAP (metronidazole, minocycline, and ciprofloxacin), used for these therapies, can generate cytotoxicity and dentin discoloration. In contrast, host defense peptides (HDPs) are promising antimicrobial and immunomodulatory biomolecules for dentistry. This study aimed to evaluate in vitro the antimicrobial activity (against Staphylococcus aureus ...
Tópico(s): Dental Trauma and Treatments
2020 - Elsevier BV | Microbial Pathogenesis

Maurício Gonçalves C. Sousa, Mariana Rocha Maximiano, Rosiane Andrade da Costa, Taia Maria Berto Rezende, Octávio Luiz Franco,
Introduction Due to the complexity of different oral infections, new anti-infective nanotechnological approaches have been emerging for dentistry in recent years. These strategies may contribute to antimicrobial molecules delivery, tissue regeneration, and oral health maintenance by acting in a more specific site and not being cytotoxic. In this context, nanofibers appear as versatile structures and might act both in the release of antimicrobial molecules and as a scaffold for new tissue formation. ...
Tópico(s): Dental materials and restorations
2020 - Taylor & Francis | Expert Opinion on Drug Delivery

Raphael Lima de Paiva, Rodrigo de Souza Ruzzi, Letícia Raquel de Oliveira, Ênio Pedone Bandarra Filho, Luiz Maurício Gonçalves Neto, Rogério Valentim Gelamo, Rosemar Batista da Silva,
Tópico(s): Lubricants and Their Additives
2020 - Springer Science+Business Media | The International Journal of Advanced Manufacturing Technology

Maurício Gonçalves Bilharva, Carlos Martins, Jonas Janner Hamann, Diniz Fronza, Rudinei De Marco, Marcelo Barbosa Malgarim,
Tópico(s): Nuts composition and effects
2018 - Sciencedomain International | Journal of Experimental Agriculture International
Glauco Adrieno Westphal, Aline Braz Pereira, Silvia Maria Fachin, Geonice Sperotto, Maurício Gonçalves, Lucimeri Albino, Rodolfo Bittencourt, Vanessa de Rossi Franzini, Álvaro Köenig,
To describe the improvements of an early warning system for the identification of septic patients on the time to diagnosis, antibiotic delivery, and mortality.
Tópico(s): Emergency and Acute Care Studies
2018 - Associação de Medicina Intensiva Brasileira | Revista Brasileira de Terapia Intensiva

Lubhandwa Sebastian Biswaro, Maurício Gonçalves da Costa Sousa, Taia Maria Berto Rezende, Simoni Campos Dias, Octávio Luiz Franco,
Antimicrobial peptides are sequences of amino acids, which present activity against microorganisms. These peptides were discovered over 70 years ago, and are abundant in nature from soil bacteria, insects, amphibians to mammals and plants. They vary in amino acids number, the distance between amino acids within individual peptide structure, net charge, solubility and other physical-chemical properties as well as differ in mechanism of action. These peptides may provide an alternative treatment to ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2018 - Frontiers Media | Frontiers in Microbiology

Stella Maris de Freitas Lima, Mirna S. Freire, Ana Luisa O. Gomes, Ana Paula de Castro Cantuária, Flávia Rodrigues P. Dutra, Beatriz Simas Magalhães, Maurício Gonçalves C. Sousa, Ludovico Migliolo, Jeeser Alves de Almeida, Octávio Luiz Franco, Taia Maria Berto Rezende,
Tópico(s): Endodontics and Root Canal Treatments
2017 - Elsevier BV | Peptides

Stella Maris de Freitas Lima, Maurício Gonçalves da Costa Sousa, Mirna de Souza Freire, Jeeser Alves de Almeida, Ana Paula de Castro Cantuária, Thaís Angélica Machado E Silva, Camila Guimarães de Freitas, Simoni Campos Dias, Octávio Luiz Franco, Taia Maria Berto Rezende,
Persistent microorganisms such as Candida albicans and Enterococcus faecalis might be directly related to endodontic treatment failure. The host response to these microorganisms impairs the reestablishment of intraradicular and periradicular health.The present investigation evaluated the expression of inflammatory mediators produced by RAW 264.7 cells in the presence of heat-killed antigens (HK) C. albicans and E. faecalis. Cultures of RAW cells were stimulated with both antigens in the presence ...
Tópico(s): Dental Radiography and Imaging
2015 - Elsevier BV | Journal of Endodontics

Silas Garrido Teixeira de Carvalho Santos, Paulo Mauricio Gonçalves Júnior, Geyson Daniel dos Santos Silva, Roberto Souto Maior de Barros,
The extraction of knowledge from data streams is an activity that has progressively been receiving an increased demand. However, in this type of environment, changes in data distribution, or concept drift, can occur constantly and is a challenge. This paper proposes the Adaptable Diversity-based Online Boosting (ADOB), a modified version of the online boosting, as proposed by Oza and Russell, which is aimed at speeding up the experts recovery after concept drifts. We performed experiments to compare ...
Tópico(s): Advanced Bandit Algorithms Research
2014 - Springer Science+Business Media | Lecture notes in computer science

Stella Maris de Freitas Lima, Gabriela Martins de Pádua, Maurício Gonçalves da Costa Sousa, Mirna de Souza Freire, Octávio Luiz Franco, Taia Maria Berto Rezende,
The presence/persistence of microorganisms in the pulp and periapical area corresponds to the maintenance of an exacerbated immune response that leads to the start of periradicular bone resorption and its perpetuation. In endodontic treatment, the available intracanal medications do not have all the desirable properties in the context of endodontic infection and apical periodontitis; they need to include not only strong antimicrobial performance but also an immunomodulatory and reparative activity, ...
Tópico(s): Antimicrobial Peptides and Activities
2014 - Elsevier BV | Biotechnology Advances

Pedro Giassi, Sérgio Okida, Maurício Gonçalves de Oliveira, Raimes Moraes,
Short-term cardiovascular regulation mediated by the sympathetic and parasympathetic branches of the autonomic nervous system has been investigated by multivariate autoregressive (MVAR) modeling, providing insightful analysis. MVAR models employ, as inputs, heart rate (HR), systolic blood pressure (SBP) and respiratory waveforms. ECG (from which HR series is obtained) and respiratory flow waveform (RFW) can be easily sampled from the patients. Nevertheless, the available methods for acquisition of beat- ...
Tópico(s): ECG Monitoring and Analysis
2013 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Biomedical Engineering

Rafael Scaf de Molon, Juliana Aparecida Najarro Dearo Morais-Camillo, Celso Eduardo Sakakura, Mauricio Goncalves Ferreira, Leonor Castro Monteiro Loffredo, Gulnara Scaf,
This study was performed to compare the inverted digital images and film-based images of dry pig mandibles to measure the periodontal bone defect depth.Forty 2-wall bone defects were made in the proximal region of the premolar in the dry pig mandibles. The digital and conventional radiographs were taken using a Schick sensor and Kodak F-speed intraoral film. Image manipulation (inversion) was performed using Adobe Photoshop 7.0 software. Four trained examiners made all of the radiographic measurements ...
Tópico(s): Periodontal Regeneration and Treatments
2012 - | Imaging Science in Dentistry
Josélia Rita da Silva, Rafael S. Salles, Mauricio Gonçalves Da Silva,
A escola, enquanto parte elementar da sociedade, precisa adequar suas práticas no intuito de acompanhar as novas tecnologias e as transformações sociais oriundas desses novos tempos. O papel dos gestores é fundamental nessa adequação. A Gestão Escolar precisa incentivar e contribuir para uso de novas tecnologias no contexto educacional, bem como considerar as diversas opiniões dos diferentes segmentos envolvidos direta ou indiretamente no processo educativo. Nesse sentido, este trabalho tem por ...
Tópico(s): Education Pedagogy and Practices
2022 - Brazilian Journal of Development | Brazilian Journal of Development

Ricardo Soares, Márcia Cristina Santiago de Mello, Maurício Gonçalves Margalho, Ângela Sanches Rocha, Cleyton Martins da Silva, Graciela Arbilla,
On March 11, 2020, the World Health Organization declared that the epidemic of the new Coronavirus disease (COVID-19) was out of control and had become a global zoonotic pandemic.Consequently, more than 190 countries have implemented measures to contain the outbreak of the disease, including the Lockdown, mainly to avoid the saturation of their health systems.Humanity found itself in an unprecedented disruptive moment, in which basic education was compelled to change, compulsorily, the traditional ...
Tópico(s): COVID-19 impact on air quality
2021 - Brazilian Society of Chemistry | Revista Virtual de Química

Neide Kiyoko Kondo Kamizake, Mauricio M Gonçalves, Cássia Thaïs Bussamra Vieira Zaia, Dimas Augusto Morozin Zaia,
In the present paper, a comparative study between the Kjeldahl method and several spectrophotometric methods was carried out for the determination of total proteins in a range of milk powder samples (skim milk powder, whole milk powder, whey protein powder, buttermilk powder). The most important finding of this paper was that the Bradford method could be used for the determination of total proteins in skim milk powder and whole milk powder samples (without extraction of lipids) instead of the Kjeldahl ...
Tópico(s): Animal Nutrition and Physiology
2003 - Elsevier BV | Journal of Food Composition and Analysis

Renato Veloso da Silva, Luciana Aparecida Rodrigues, Maurício Gonçalves da Silva, Bruna Gandini da Silva, Marco Antônio Martins,
ABSTRACT The association between biochar and green manure in the papaya crop may be a promising management technique, mainly in its first growth stage. This study aimed to evaluate the effects of biochar and green manure (Mucuna aterrina) on the growth and nutrition of Carica papaya seedlings, as well as on soil fertility. The experiment followed a randomized block design (5 blocks), in a 2 x 2 factorial arrangement: with and without mucuna and with and without biochar. The biochar or mucuna application ...
Tópico(s): Plant Micronutrient Interactions and Effects
2019 - UNIVERSIDADE FEDERAL DE GOIÁS | Pesquisa Agropecuária Tropical

Ricardo Antunes Dantas de Oliveira, Diego Ricardo Xavier, Maurício Gonçalves e Silva,
Snakebite accidents are considered category A neglected tropical diseases. Brazil stands out for snakebite accidents, mainly in the Amazon region. The best possible care after snakebite accidents is to obtain antiophidic sera on time. And the maximum ideal time to reach it is about 2 hours after an accident. Based on public health information and using a tool to analyze geographical accessibility, we evaluate the possibility of reaching Brazilian serum-providing health facilities from the relationship ...
Tópico(s): Mosquito-borne diseases and control
2022 - Public Library of Science | PLoS ONE

Taia Maria Berto Rezende, Antônio Paulino Ribeiro Sobrinho, Leda Quércia Vieira, Maurício Gonçalves da Costa Sousa, Toshihisa Kawai,
To evaluate the effect(s) of mineral trioxide aggregate (MTA) on in vitro RANKL-mediated osteoclast-dependent bone resorption events and the influence of Ca2+ and Al3+ on the osteoclastogenesis inhibition by MTA.Two types of osteoclast precursors, RAW 264.7 (RAW) cell line or bone marrow cells (obtained from BALB/c mice and stimulated with recombinant (r) macrophage colony stimulation factor (M-CSF), were stimulated with or without recombinant (r) activator of nuclear kappa B ligand (RANKL), in the presence ...
Tópico(s): Bone Tissue Engineering Materials
2020 - Springer Nature | Clinical Oral Investigations

Gabriel O Ribeiro, A.M. Teixeira, Frederico Osório Velasco, W. G. de Faria, Diogo Gonzaga Jayme, Rogério Martins Maurício, L.C. Gonçalves, Tim A. McAllister,
... O., Faria Jr., W. G., Jayme, D. G., Maurício, R. M., Gonçalves, L. C. and McAllister, T. A. 2015. Methane ...
Tópico(s): Agriculture Sustainability and Environmental Impact
2014 - Canadian Science Publishing | Canadian Journal of Animal Science
... P. Fontes, Josimar Daniel Gomes, Frederico P. R. Gonçalves, Maurício Guerra, Torbjørn Haugaasen, Stefanie Heiduck, Eckhard W. Heymann, ...
Tópico(s): Plant and animal studies
1986 - University of Chicago Press | The American Naturalist

Marcelo Oliveira Gomes, Luiz Maurício Gonçalves Neto, Robson Bruno Dutra Pereira, Carlos Henrique Lauro, Lincoln Cardoso Brandão,
Tópico(s): Advanced Surface Polishing Techniques
2018 - Springer Science+Business Media | The International Journal of Advanced Manufacturing Technology
Ye Yuan, Guy‐Bart Stan, Ling Shi, Mauricio Barahona, Jorge Gonçalves,
We consider the discrete-time dynamics of a network of agents that exchange information according to a nearest-neighbour protocol under which all agents are guaranteed to reach consensus asymptotically. We present a fully decentralised algorithm that allows any agent to compute the final consensus value of the whole network in finite time using the minimum number of successive values of its own state history. We show that the minimum number of steps is related to a Jordan block decomposition of ...
Tópico(s): Neural Networks Stability and Synchronization
2013 - Elsevier BV | Automatica

Luciano Fernandes Sousa, Rogério Martins Maurício, L.C. Gonçalves, E.O.S. Saliba, Guilherme Rocha Moreira,
O experimento foi realizado em sistema silvipastoril (Ssp) localizado no bioma de Cerrado, no município de Lagoa Santa, Minas Gerais, no ano agrícola de 2004-2005. Avaliou-se a influência do Ssp composto pela arbórea bolsa-de-pastor (Zeyheria tuberculosa) sobre os parâmetros produção, atributos morfogênicos, composição bromatológica e valor nutritivo da gramínea Brachiaria brizantha cv. Marandu, e os efeitos sobre as condições microclimáticas. O delineamento experimental foi em blocos ao acaso, com ...
Tópico(s): Soil Management and Crop Yield
2007 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Arquivo Brasileiro de Medicina Veterinária e Zootecnia

Luciano Caseli, D.S. dos Santos, Maurício Foschini, Débora Gonçalves, Osvaldo N. Oliveira,
The molecular engineering capability of the layer-by-layer (LbL) method for fabricating thin films has been exploited in order to immobilize glucose oxidase (GOD) in films with alternating layers of chitosan. Chitosan was proven a good scaffolding material, as GOD molecules preserved their catalytic activity towards glucose oxidation. Using electrochemical measurements, we showed that chitosan/GOD LbL films can be used to detect glucose with a limit of detection of 0.2 mmol l−1 and an activity of ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2006 - Elsevier BV | Journal of Colloid and Interface Science

Ú.T. Nogueira, Rogério Martins Maurício, L.C. Gonçalves,
Estudou-se a diferença entre a produção de gases (PG) e a degradação da matéria seca (DMS) para substratos com diferentes quantidades de carboidratos solúveis avaliados pela técnica in vitro de produção de gases. Foram utilizados cinco substratos (cana-de-açúcar, silagem de milho, capim-colonião, milho em grão e ração comercial para vacas em lactação) antes e após a retirada parcial dos carboidratos solúveis (lavados). A PG foi maior e a DMS menor para o material lavado. A concentração de carboidratos ...
Tópico(s): Ruminant Nutrition and Digestive Physiology
2006 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Arquivo Brasileiro de Medicina Veterinária e Zootecnia

Luciano Caseli, D.S. dos Santos, Maurício Foschini, Débora Gonçalves, Osvaldo N. Oliveira,
The suitability of the layer-by-layer (LbL) technique, based on the alternate adsorption of oppositely charged materials, for immobilization of biomolecules has been well established. Achieving optimized results depends on the experimental conditions for film fabrication, and in most cases on the film architecture. In this paper we exploit the high catalytic activity of glucose oxidase (GOD) immobilized in LbL films with chitosan in oxidation reactions of glucose to gluconic acid. In addition to confirming ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2006 - Elsevier BV | Materials Science and Engineering C