Produção Nacional
Revisado por pares
Christian M. Becker, Neil P. Johnson, Sawsan As‐Sanie, Juan Camilo Arjona Ferreira, Maurício Simões Abrão, Krzysztof Wilk, So Jung Imm, Vandana Mathur, Julie Stein Perry, Rachel B. Wagman, Linda C. Giudice,
Abstract STUDY QUESTION What is the efficacy and safety of long-term treatment (up to 2 years) with relugolix combination therapy (CT) in women with moderate to severe endometriosis-associated pain? SUMMARY ANSWER For up to 2 years, treatment with relugolix CT improved menstrual and non-menstrual pain, dyspareunia, and function in women with endometriosis; after an initial decline of <1%, the mean bone mineral density (BMD) remained stable with continued treatment. WHAT IS KNOWN ALREADY Endometriosis ...
Tópico(s): Pregnancy-related medical research
2024 - Oxford University Press | Human Reproduction
José Augusto Simões, Kathleen Alberto, Pedro Augusto Simões, Katia Maurício, Inês Rosendo, Luiz Miguel Santiago,
... Manager, RefWorks, Zotero AMA Simões JA, Alberto KP, Simões PA, Maurício K, Rosendo I, Santiago L. Communication and health: ... Simões, José A, Kathleen P Alberto, Pedro A Simões, Katia Maurício, Inês Rosendo, and Luiz Miguel Santiago. 2019. "Communication ... fmpcr.2019.90169. Harvard Simões, J., Alberto, K., Simões, P., Maurício, K., Rosendo, I., and Santiago, L. (2019). Communication ... fmpcr.2019.90169. Vancouver Simões J, Alberto K, Simões P, Maurício K, Rosendo I, Santiago L. Communication and health: ...
Tópico(s): Healthcare cost, quality, practices
2019 - Continuo | Family Medicine & Primary Care Review
Produção Nacional
Revisado por pares
М. Canis, Jason Abbott, Maurício Simões Abrão, Moamar Al‐Jefout, Mohamed A. Bedaiwy, Giuseppe Benagiano, Katherine A. Burns, М. Canis, Francisco Carmona, Charles Chapron, Hilary Critchley, Dominique de Ziegler, Tommaso Falcone, Asgerally T. Fazleabas, Simone Ferrero, Juan A. García-Velasco, Caroline E. Gargett, Erin Greaves, Linda G. Griffith, Sun-Wei Guo, Marwan Habiba, Tasuku Harada, M. Louise Hull, Neil P. Johnson, Yuval Kaufman, Keith B Issacson, Khaleque Newaz Khan, Mee‐Ran Kim, Philippe A. Koninckx, Bruce A. Lessey, Dan C. Martin, Sachiko Matsuzaki, Gita D. Mishra, Yutaka Osuga, Felice Petraglia, А А Попов, Horace Roman, Andrea Romano, Philippa T. K. Saunders, Tamer Seckin, Edgardo Somigliana, Hugh S. Taylor, Robert N. Taylor, Paolo Vercellini, Paola Viganò,
This group was formed out of the conviction that endometriosis research has not progressed at a pace in proportion to disease severity and the negative impact on women's quality of life. Furthermore, advancement in our understanding of this condition requires a quantum shift based on new theories of disease pathogenesis. With this conviction, this international group calls for new theories that may improve the understanding of this condition, leading to optimized management or even prevention. To ...
Tópico(s): Gynecological conditions and treatments
2024 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
G. Condous, B. Gerges, Isabelle Thomassin‐Naggara, Christian M. Becker, Carla Tomassetti, Harald Krentel, Bruno J. van Herendael, Mario Malzoni, Maurício Simões Abrão, Ertan Sarıdoğan, J. Keckstein, Gernot Hudelist,
The International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) and International Deep Endometriosis Analysis (IDEA) group, the European Endometriosis League (EEL), the European Society for Gynaecological Endoscopy (ESGE), the European Society of Human Reproduction and Embryology (ESHRE), the International Society for Gynecologic Endoscopy (ISGE), the American Association of Gynecologic Laparoscopists (AAGL) and the European Society of Urogenital Radiology (ESUR) elected an international, multidisciplinary ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2024 - Wiley | Ultrasound in Obstetrics and Gynecology
Produção Nacional
Revisado por pares
S. Guerriero, G. Condous, Martino Rolla, Gernot Hudelist, Simone Ferrero, Juan Luis Alcázar, S. Ajossa, Céline Bafort, Dominique Van Schoubroeck, T. Bourne, T. Van den Bosch, S.S. Singh, Maurício Simões Abrão, Gábor Szabó, A. C. Testa, A. Di Giovanni, D. Fischerová, Carla Tomassetti, D. Timmerman,
ABSTRACT Preoperative sonographic staging in patients with suspected parametrial endometriosis is essential to plan surgical intervention and anticipate the need for a multidisciplinary approach, and thus optimize surgical outcome. The results of a recent meta‐analysis suggest that there is a need to define more accurately the ultrasonographic criteria for parametrial involvement in endometriosis. This addendum to the International Deep Endometriosis Analysis (IDEA) consensus highlights the sonographic ...
Tópico(s): Gynecological conditions and treatments
2023 - Wiley | Ultrasound in Obstetrics and Gynecology
Produção Nacional
Revisado por pares
Sheila M. A. Matos, Sandra Rêgo de Jesus, Silvia RDM Saldiva, Matildes S. Prado, Silvana D’Innocenzo, Ana MO Assis, Laura C. Rodrigues, Neuza Maria Alcântara‐Neves, Álvaro A. Cruz, Sílvia de Magalhães Simões, Maurício L. Barreto,
To evaluate the association between overweight and the occurrence of asthma and atopy in a cohort of children of 4-12 years of age living in the city of Salvador in 2005.Cross-sectional study nested in a cohort.The metropolitan region of Salvador, Bahia, Brazil.The study included 1129 children of 4-12 years age who presented complete information on the variables used here. Skin tests for allergy, spirometry, faecal parasitology, serum IgE and anthropometric surveys were conducted. Poisson's multivariate ...
Tópico(s): Obesity, Physical Activity, Diet
2011 - Cambridge University Press | Public Health Nutrition
Produção Nacional
Revisado por pares
Samuel Ângelo Diógenes da Costa, João Carlos Ker, Diana Ferreira de Freitas Simões, Maurício Paulo Ferreira Fontes, José Domingos Fabris, Felipe Vaz Andrade,
Localizado na porção centro-oeste do Estado de Minas Gerais, o Quadrilátero Ferrífero abrange uma área de aproximadamente 7.000 km². Desde o século XVII, a região é conhecida como uma província aurífera e ferrífera, sendo por essa razão uma das regiões mais bem estudadas do Brasil no contexto geológico. A região é de topografia muito acidentada, onde predominam solos pouco evoluídos pedogeneticamente, com destaque para Cambissolos Háplicos, Neossolos Litólicos e Neossolos Regolíticos. Em menor proporção ...
Tópico(s): Soil Management and Crop Yield
2014 - Sociedade Brasileira de Ciência do Solo | Revista Brasileira de Ciência do Solo
Produção Nacional
Revisado por pares
Maurício Simões Abrão, Marina Paula Andres, Julian A. Gingold, Mariona Rius, João Siufi Neto, Manoel Orlando Gonçalves, A. Di Giovanni, Mario Malzoni, Francisco Carmona,
ABSTRACT Study Objective To compare the accuracy of preoperative ultrasound (US) in predicting the laparoscopically defined 2021 American Association of Gynecologic Laparoscopists (AAGL) Endometriosis Staging. Design Retrospective multicenter study of patients treated at 3 specialized endometriosis centers. Setting Three specialized endometriosis surgical centers in São Paulo (Brazil), Barcelona (Spain), and Avellino (Italy) participated. Patients A total of 878 patients aged 15 to 45 years with no history of ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2022 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Edgar A. Silveira, Maurício Simões Santanna, Normando Perazzo Barbosa Souto, Giulia Cruz Lamas, Luiz Gustavo Oliveira Galvão, Sandra M. Luz, Armando Caldeira-Pires,
Tópico(s): Natural Fiber Reinforced Composites
2022 - Springer Science+Business Media | Journal of Thermal Analysis and Calorimetry
Produção Nacional
Revisado por pares
Linda C. Giudice, Sawsan As‐Sanie, Juan Camilo Arjona Ferreira, Christian M. Becker, Maurício Simões Abrão, Bruce A. Lessey, Eric J. Brown, Krzysztof Dynowski, Krzysztof Wilk, Yulan Li, Vandana Mathur, Qurratul Ann Warsi, Rachel B. Wagman, Neil Johnson,
BackgroundEndometriosis is a common cause of pelvic pain in women, for which current treatment options are suboptimal. Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, combined with estradiol and a progestin, was evaluated for treatment of endometriosis-associated pain.MethodsIn these two replicate, phase 3, multicentre, randomised, double-blind, placebo-controlled trials at 219 community and hospital research centres in Africa, Australasia, Europe, North America, and South ...
Tópico(s): Gynecological conditions and treatments
2022 - Elsevier BV | The Lancet
Produção Nacional
Revisado por pares
Erica Pascoal, Jocelyn M. Wessels, M. K. Aas‐Eng, Maurício Simões Abrão, G. Condous, D. Jurkovic, Mercedes Espada, C. Exacoustòs, Simone Ferrero, S. Guerriero, Gernot Hudelist, Mario Malzoni, S. Reid, S. Tang, Carla Tomassetti, Sukhbir S. Singh, T. Van den Bosch, Mathew Leonardi,
Abstract Endometriosis is a chronic systemic disease that can cause pain, infertility and reduced quality of life. Diagnosing endometriosis remains challenging, which yields diagnostic delays for patients. Research on diagnostic test accuracy in endometriosis can be difficult due to verification bias, as not all patients with endometriosis undergo definitive diagnostic testing. The purpose of this State‐of‐the‐Art Review is to provide a comprehensive update on the strengths and limitations of the ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2022 - Wiley | Ultrasound in Obstetrics and Gynecology
Produção Nacional
Revisado por pares
Manoel Orlando Gonçalves, João Siufi Neto, Marina Paula Andres, Daniela Siufi, Leandro Accardo de Mattos, Maurício Simões Abrão,
Abstract STUDY QUESTION What is the sensitivity and the specificity of preoperative transvaginal ultrasound with bowel preparation (TVUS-BP) compared to diagnostic laparoscopy (DL) for the identification of ovarian and deep sites of endometriosis? SUMMARY ANSWER DL was able to detect retrocervical, ovarian, and bladder endometriosis with similar sensitivity and specificity as TVUS-BP, whereas for vaginal and rectosigmoid endometriosis, DL had lower sensitivity and specificity than TVUS-BP. WHAT IS ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2021 - Oxford University Press | Human Reproduction
Produção Nacional
Revisado por pares
F. Okita, Maurício Simões Abrão, Lúcia Alves da Silva Lara, Marina Paula Andres, Camila Tomé da Cunha, L.G. Oliviera Brito,
Study Objective To assess the prevalence of endometriosis in transgender men during surgery and clinical treatment for the reported symptoms. Design Systematic review. Setting N/A. Patients or Participants Transgender men that were being treated at their institutions with or without presenting pelvic pain at the time of their investigation. Interventions A literature search was performed using the PubMed, Embase, Web of Science (WOS) and AAGL JMIG Abstracts since inception to April 4th, 2021, with ...
Tópico(s): Uterine Myomas and Treatments
2021 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Paulo Arantes Laginha, Fernanda Vieira Lins Arcoverde, Luiza Gama Coelho Riccio, Marina Paula Andres, Maurício Simões Abrão,
Endometriosis (EDT), a common estrogen-dependent inflammatory disorder, is characterized by endometrial-like tissue outside the uterus. While its pathogenesis is poorly understood, it is supposed that the immune system plays a role in its pathophysiology, and increased number of immune cells and changes in both cell-mediated and humoral immunity have been described. Dendritic cells (DCs) are antigen-presenting cells (APC) of the immune system that recognize, capture, and process complex antigens and ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2021 - Elsevier BV | Journal of Reproductive Immunology
Produção Nacional
Revisado por pares
Carla Tomassetti, Neil Johnson, John C. Petrozza, Maurício Simões Abrão, Jon I. Einarsson, Andrew W. Horne, Ted T.M. Lee, Stacey A. Missmer, Nathalie Vermeulen, Krina T. Zondervan, Grigoris Grimbizis, Rudy Leon De Wilde,
Can a set of terms and definitions be prepared on endometriosis that would be the basis for standardization in disease description, classification and research?The current paper outlines a list of 49 terms and definitions in the field of endometriosis.Different classification systems have been developed for endometriosis, using different definitions for the disease, the different subtypes, symptoms and treatments. In addition, an International Glossary on Infertility and Fertility Care was published ...
Tópico(s): Gynecological conditions and treatments
2021 - Oxford University Press | Human Reproduction Open
Produção Nacional
Revisado por pares
Maurício Simões Abrão, Marina Paula Andres, Charles E. Miller, Julian A. Gingold, Mariona Rius, João Siufi Neto, Francisco Carmona,
ABSTRACT Study Objective To develop a new endometriosis classification system for scoring intraoperative surgical complexity and to examine its correlation with patient-reported pain and infertility. Design Multicenter study of patients treated at 3 recognized endometriosis centers. Setting Three specialized endometriosis surgical centers in São Paulo, Brazil and Barcelona, Spain. Patients Patients aged 15 to 45 years with histologically proven endometriosis and no history of pelvic malignancy underwent ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2021 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Gemma Casals, María Carrera, José Domínguez, Maurício Simões Abrão, Francisco Carmona,
ObjectiveThe aims of this systematic review and meta-analysis were to compare reproductive outcomes in patients who underwent surgery for deep infiltrative endometriosis (DIE) before in vitro fertilization (IVF) with those in patients who underwent IVF without a previous surgery for DIE, to analyze data according to different types of surgery (complete or incomplete) or subgroups of patients (DIE with or without bowel involvement), and to assess surgical and IVF complications and data regarding safety ...
Tópico(s): Gynecological conditions and treatments
2021 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Carla Tomassetti, Neil Johnson, John C. Petrozza, Maurício Simões Abrão, Jon I. Einarsson, Andrew W. Horne, Ted T.M. Lee, Stacey A. Missmer, Nathalie Vermeulen, Krina T. Zondervan, Grigoris Grimbizis, Rudy Leon De Wilde,
Different classification systems have been developed for endometriosis, using different definitions for the disease, the different subtypes, symptoms and treatments. In addition, an International Glossary on Infertility and Fertility Care has been published in 2017 by the International Committee for Monitoring Assisted Reproductive Technologies (ICMART) in collaboration with other organisations. An international working group convened over the development of a classification or descriptive system ...
Tópico(s): Gynecological conditions and treatments
2021 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Nathalie Vermeulen, Maurício Simões Abrão, Jon I. Einarsson, Andrew W. Horne, Neil Johnson, Ted T.M. Lee, Stacey A. Missmer, John C. Petrozza, Carla Tomassetti, Krina T. Zondervan, Grigoris Grimbizis, Rudy Leon De Wilde,
Which endometriosis classification, staging and reporting systems have been published and validated for use in clinical practice?Of the 22 endometriosis classification, staging and reporting systems identified in this historical overview, only a few have been evaluated, in 46 studies, for the purpose for which they were developed.In the field of endometriosis, several classification, staging and reporting systems have been developed.A systematic PUBMED literature search was performed. Data were ...
Tópico(s): Gynecological conditions and treatments
2021 - Oxford University Press | Human Reproduction Open
Produção Nacional
Revisado por pares
Nathalie Vermeulen, Maurício Simões Abrão, Jon I. Einarsson, Andrew W. Horne, Neil Johnson, Ted T.M. Lee, Stacey A. Missmer, John C. Petrozza, Carla Tomassetti, Krina T. Zondervan, Grigoris Grimbizis, Rudy Leon De Wilde,
ObjectiveIn the field of endometriosis, several classification, staging and reporting systems have been developed. Which endometriosis classification, staging and reporting systems have been published and validated for use in clinical practice?Data sourcesA systematic PUBMED literature search was performed. Data were extracted and summarized.Methods of study selectionnaTabulation, integration and resultsTwenty-two endometriosis classification, staging and reporting systems have been published between ...
Tópico(s): Uterine Myomas and Treatments
2021 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Carla Tomassetti, Neil Johnson, John C. Petrozza, Maurício Simões Abrão, Jon I. Einarsson, Andrew W. Horne, T.T.M. Lee, Stacey A. Missmer, Nathalie Vermeulen, Krina T. Zondervan, Grigoris Grimbizis, Rudy Leon De Wilde,
Different classification systems have been developed for endometriosis, using different definitions for the disease, the different subtypes, symptoms and treatments. In addition, an International Glossary on Infertility and Fertility Care was published in 2017 by the International Committee for Monitoring Assisted Reproductive Technologies (ICMART) in collaboration with other organisations. An international working group convened over the development of a classification or descriptive system for ...
Tópico(s): Gynecological conditions and treatments
2021 - | Facts Views and Vision in ObGyn
Produção Nacional
Revisado por pares
Allison Perrotta, Giuliano Moysés Borrelli, Carlo Martins, Esper G. Kallás, Sabri Saeed Sanabani, Linda G. Griffith, Eric J. Alm, Maurício Simões Abrão,
Endometriosis remains a challenge to understand and to diagnose. This is an observational cross-sectional pilot study to characterize the gut and vaginal microbiome profiles among endometriosis patients and control subjects without the disease and to explore their potential use as a less-invasive diagnostic tool for endometriosis. Overall, 59 women were included, n = 35 with endometriosis and n = 24 controls. Rectal and vaginal samples were collected in two different periods of the menstrual cycle from ...
Tópico(s): Gynecological conditions and treatments
2020 - Springer Nature | Reproductive Sciences
Produção Nacional
Revisado por pares
Maurício Simões Abrão, Marina Paula Andres, Mariana da Cunha Vieira, Giuliano Moysés Borrelli, João Siufi Neto,
Tópico(s): Intestinal and Peritoneal Adhesions
2020 - Springer Nature | Reproductive Sciences
Produção Nacional
Revisado por pares
Fernando Lorenzetti da Cunha, Fernanda Vieira Lins Arcoverde, Marina Paula Andres, Daniel Coser Gomes, Carlos Ricardo Doi Bautzer, Maurício Simões Abrão, Marcos Tobias‐Machado,
To review the literature for the preoperative clinical characteristics, surgical findings, and outcomes of patients who underwent laparoscopic surgical treatment of ureteral endometriosis (UE).A systematic search was performed in the PubMed and Scopus databases.Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, studies in English language that assessed UE treated surgically by laparoscopy published between 2008 and 2020 were selected.In an initial search, 1313 ...
Tópico(s): Maternal and fetal healthcare
2020 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Charles Chapron, Silvia Vannuccini, Piétro Santulli, Maurício Simões Abrão, Francisco Carmona, Ian S. Fraser, Stephan Gordts, Sun‐Wei Guo, Pierre‐Alexandre Just, Jean‐Christophe Noël, George Pistofidis, T. Van den Bosch, Felice Petraglia,
Adenomyosis is a benign uterine disorder where endometrial glands and stroma are pathologically demonstrated within the uterine myometrium. The pathogenesis involves sex steroid hormone abnormalities, inflammation, fibrosis and neuroangiogenesis, even though the proposed mechanisms are not fully understood. For many years, adenomyosis has been considered a histopathological diagnosis made after hysterectomy, classically performed in perimenopausal women with abnormal uterine bleeding (AUB) or pelvic ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2020 - Oxford University Press | Human Reproduction Update
Produção Nacional
Revisado por pares
Mohamed Jeljeli, Luiza Gama Coelho Riccio, Sandrine Chouzenoux, Fabiana Moresi, Laurie Toullec, Ludivine Doridot, Carole Nicco, Mathilde Bourdon, Louis Marcellin, Piétro Santulli, Maurício Simões Abrão, Charles Chapron, Frédéric Batteux,
Endometriosis is a frequent, chronic, inflammatory gynecological disease characterized by the presence of ectopic endometrial tissue causing pain and infertility. Macrophages have a central role in lesion establishment and maintenance by driving chronic inflammation and tissue remodeling. Macrophages can be reprogrammed to acquire memory-like characteristics after antigenic challenge to reinforce or inhibit a subsequent immune response, a phenomenon termed "trained immunity." Here, whereas bacille ...
Tópico(s): Pregnancy and Medication Impact
2020 - Cell Press | Cell Reports
Produção Nacional
Revisado por pares
Sarah L. Cohen, Grace Liu, Maurício Simões Abrão, Neil Smart, Todd B. Heniford,
Primum non nocere: First, do no harm. This is a professional and ethical imperative with which we as physicians are very familiar. Can we expand this principle to include the patient and the healthcare team? As minimally invasive surgeons and ambassadors, the authors could never have imagined penning a document that argues the merits of traditional open surgery. We are all ardent supporters of minimally invasive techniques and the myriad benefits they afford. However, we now find ourselves in the ...
Tópico(s): Climate Change and Health Impacts
2020 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Jéssica Vilarinho Cardoso, Daniel Escorsim Machado, Mayara Calixto da Silva, Plínio Tostes Berardo, Renato Ferrari, Maurício Simões Abrão, Jamila Alessandra Perini,
Abstract Objectives: to describe the epidemiological and clinical profile of women with endometriosis and to determine the association with the prognostic characteristics of the disease. Methods: retrospective descriptive study involving 237 women attended at two referral hospitals for endometriosis, between 2011 and 2017. Associations between groups were estimated using logistic regression models. Results: most women (65.4%) were of reproductive age (29-39 years), with a body mass index in the range ...
Tópico(s): Gynecological conditions and treatments
2020 - Instituto Materno Infantil de Pernambuco | Revista Brasileira de Saúde Materno Infantil
Produção Nacional
Revisado por pares
Marina Paula Andres, Fernanda Vieira Lins Arcoverde, Carolina C.C. Souza, Luiz Flávio Cordeiro Fernandes, Maurício Simões Abrão, Rosanne M. Kho,
To conduct a systematic review of the literature on patients with extrapelvic deep endometriosis.A thorough search of the PubMed/Medline, Embase, and Cochrane databases was performed.Studies in the last 20 years that reported on primary extrapelvic endometriosis were included (PROSPERO registration number CRD42019125370).The initial search identified 5465 articles, and 179 articles, mostly case reports and series, were included. A total of 230 parietal (PE), 43 visceral (VE), 628 thoracic (TE), 6 central ...
Tópico(s): Gynecological conditions and treatments
2019 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Maurício Simões Abrão, Marina Paula Andres, Rodrigo Nobrega Barbosa, Marco Bassi, Rosanne M. Kho,
To validate the algorithm for selective bowel surgery based on preoperative imaging by comparing the perioperative outcomes of patients who undergo each type of bowel surgery for deep bowel disease, and secondarily to evaluate the incidence, factors, and subsequent outcomes when the actual procedure performed deviated from the preoperative surgical plan.Retrospective study comparing 3 surgical interventions in an intention-to-treat analysis.Tertiary care hospital.Women with significant pain (visual ...
Tópico(s): Uterine Myomas and Treatments
2019 - Elsevier BV | Journal of Minimally Invasive Gynecology